diflunisal has been researched along with iododiflunisal in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Arsequell, G; Blasi, D; Bosch, L; Centeno, NB; Cotrina, EY; Pinto, M; Planas, A; Quintana, J; Valencia, G; Vilà, M | 1 |
| Arsequell, G; Damas, AM; Gales, L; Macedo-Ribeiro, S; Saraiva, MJ; Valencia, G | 1 |
| Cardoso, I; Ribeiro, CA; Saraiva, MJ | 1 |
| Arsequell, G; Cardoso, I; Guido, LF; Magalhães, A; Oliveira, SM; Ribeiro, CA; Saraiva, MJ; Valencia, G | 1 |
| Almeida, MR; Arsequell, G; Ballesteros, A; La Parra, JR; Nieto, J; Planas, A; Valencia, G; Vilaró, M | 1 |
| Alemi, M; Cardoso, I; Santana, I; Silva, SC | 1 |
| Alemi, M; Arsequell, G; Blasi, D; Cardoso, I; Cotrina, EY; Gimeno, A; Jiménez-Barbero, J; Llop, J; Quintana, J; Rivas, J; Santos, LM; Valencia, G | 1 |
| Alemi, M; Arsequell, G; Cardoso, I; Cossío, U; Cotrina, EY; Gómez-Vallejo, V; Jiménez-Barbero, J; Llop, J; Martín, A; Morcillo, MÁ; Quintana, J; Rios, X; Valencia, G | 1 |
| Arsequell, G; Baz, Z; Cardoso, I; Cossío, U; Cotrina, EY; Gião, T; Gómez-Vallejo, V; Jiménez-Barbero, J; Llop, J; Mujica, E; Quintana, J; Rejc, L; Rios, X | 1 |
| Arsequell, G; Cardoso, I; Cotrina, EY; Gales, L; Leite, JP; Llop, J; Oliveira, Â; Quintana, J | 1 |
| Abad-Zapatero, C; Arsequell, G; Blasi, D; Centeno, NB; Cotrina, EY; Planas, A; Quintana, J; Vilà, M | 1 |
11 other study(ies) available for diflunisal and iododiflunisal
| Article | Year |
|---|---|
Modulation of the fibrillogenesis inhibition properties of two transthyretin ligands by halogenation.
Topics: Diflunisal; Flufenamic Acid; Halogenation; Humans; Kinetics; Ligands; Models, Molecular; Prealbumin; Protein Multimerization; Protein Structure, Secondary; Structure-Activity Relationship | 2013 |
Human transthyretin in complex with iododiflunisal: structural features associated with a potent amyloid inhibitor.
Topics: Amyloid; Binding Sites; Diflunisal; Humans; Models, Molecular; Molecular Structure; Prealbumin; Protein Binding | 2005 |
Stability of the transthyretin molecule as a key factor in the interaction with a-beta peptide--relevance in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Cell Line, Tumor; Diflunisal; Dinitrophenols; Humans; Mutation; Phthalic Acids; Prealbumin; Protein Binding; Resveratrol; Stilbenes | 2012 |
Transthyretin stabilization by iododiflunisal promotes amyloid-β peptide clearance, decreases its deposition, and ameliorates cognitive deficits in an Alzheimer's disease mouse model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cognition Disorders; Diflunisal; Humans; Maze Learning; Mice; Mice, Transgenic; Nootropic Agents; Peptide Fragments; Plaque, Amyloid; Prealbumin; Presenilin-1 | 2014 |
Tuning transthyretin amyloidosis inhibition properties of iododiflunisal by combinatorial engineering of the nonsalicylic ring substitutions.
Topics: Amyloid Neuropathies, Familial; Combinatorial Chemistry Techniques; Diflunisal; Humans; Structure-Activity Relationship | 2015 |
Transthyretin stability is critical in assisting beta amyloid clearance- Relevance of transthyretin stabilization in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blood-Brain Barrier; Cell Line; Diflunisal; Escherichia coli; Humans; Liver; Low Density Lipoprotein Receptor-Related Protein-1; Lysosomes; Mice, Transgenic; Prealbumin; Presenilin-1; Protein Denaturation; Protein Multimerization; Protein Stability; Receptors, LDL; Recombinant Proteins; Tumor Suppressor Proteins; Urea | 2017 |
Insights on the Interaction between Transthyretin and Aβ in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Crystallography, X-Ray; Diflunisal; Humans; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Prealbumin; Protein Interaction Maps | 2017 |
Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD.
Topics: Administration, Intravenous; Amyloid beta-Peptides; Animals; Autoradiography; Blood-Brain Barrier; Brain; Diflunisal; Iodine Radioisotopes; Mice; Positron-Emission Tomography; Prealbumin; Tissue Distribution | 2019 |
Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in vivo Molecular Imaging Study1.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Diflunisal; Female; Hippocampus; Longitudinal Studies; Mice; Mice, 129 Strain; Mice, Inbred C3H; Mice, Transgenic; Molecular Imaging; Positron Emission Tomography Computed Tomography | 2020 |
Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer.
Topics: Amyloid; Benzbromarone; Benzoxazoles; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Diflunisal; Drug Repositioning; Gene Expression; Humans; Hydrogen Bonding; Kinetics; Molecular Docking Simulation; Neuroprotective Agents; Prealbumin; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Stability; Recombinant Proteins; Thermodynamics; Thyroxine; Tolcapone | 2020 |
Optimization of kinetic stabilizers of tetrameric transthyretin: A prospective ligand efficiency-guided approach.
Topics: Diflunisal; Humans; Kinetics; Ligands; Mutagenesis, Site-Directed; Prealbumin; Protein Binding; Protein Multimerization; Structure-Activity Relationship | 2020 |