diflunisal and acetaminophen

diflunisal has been researched along with acetaminophen in 48 studies

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199024 (50.00)18.7374
1990's6 (12.50)18.2507
2000's10 (20.83)29.6817
2010's8 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Chang, TK; Ensom, MH; Kiang, TK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Grad, HA; Haas, DA1
Chau, M; Rodrigo, C; Rosenquist, J1
Chandramouli, V; Kumaran, K; Landau, BR; Magnusson, I; Schumann, WC; Wahren, J2
DeForge, B; King, DE; Muncie, HL1
Bodison, S; Brown, FL; Davis, W; Dixon, J; Nowoslawski, J1
Gustafsson, I; Nyström, E; Quiding, H1
Aghababian, RV1
Chapman, PJ1
Cheung, LK; Rodrigo, MR; Rosenquist, JB1
Indelicato, PA2
Folcik, MA; Fulkerson, JP1
Seymour, RA1
Hickey, RF1
Altman, RD1
Standnes, B; Weber, H1
Cronberg, S; Söderberg, I; Wallmark, E1
Amadio, P1
Deuben, RR1
Beaver, WT; Forbes, JA; Neilson, GB; Shackleford, RW; White, EH; White, RW1
Humes, JL; Kuehl, FA; Sadowski, SJ; Winter, CA1
Bowerman, JE; Irvine, GH; Lutterloch, MJ1
Strunin, L; White, P1
Bellibas, SE; Gomel, M; Köse, T; Selçuk, E; Tuğlular, I1
Kir, S; Sençift, K; Tuncer, M1
Meunier, CJ; Verbeeck, RK1
Bebawy, LI; El-Kousy, NM1
Comfort, MB; McGrath, C; Tsang, AC; Tse, AS1
Price, SL1
Davey, J1
Biles, CL; Broge, M; Cluck, T; Dahal, S; Dalmont, K; Gurung, T; Howard, A; Konsure, H; Poudyal, S; Rowsey, T; Shrestha, S1

Reviews

6 review(s) available for diflunisal and acetaminophen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug therapy for the elderly: what are our concerns in dentistry?
    University of Toronto dental journal, 1991,Fall, Volume: 5, Issue:1

    Topics: Acetaminophen; Aged; Aging; Anesthetics, Local; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Dental Care for Aged; Diflunisal; Drug Interactions; Drug Therapy; Humans; Naproxen; Narcotics

1991
Review of ibuprofen for osteoarthritis.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin

1984
The computational prediction of pharmaceutical crystal structures and polymorphism.
    Advanced drug delivery reviews, 2004, Feb-23, Volume: 56, Issue:3

    Topics: Acetaminophen; Allopurinol; Aspirin; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Computer Simulation; Crystallography; Databases, Factual; Diflunisal; Hormones; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Conformation; Molecular Structure; Pharmaceutical Preparations; Phase Transition; Software; Static Electricity; Technology, Pharmaceutical; Thermodynamics

2004

Trials

16 trial(s) available for diflunisal and acetaminophen

ArticleYear
A comparison of paracetamol and diflunisal for pain control following 3rd molar surgery.
    International journal of oral and maxillofacial surgery, 1989, Volume: 18, Issue:3

    Topics: Acetaminophen; Adult; Diflunisal; Double-Blind Method; Female; Humans; Male; Molar, Third; Pain, Postoperative; Premedication; Random Allocation; Salicylates; Time Factors; Tooth Extraction

1989
Treatment of mild to moderate pain of acute soft tissue injury: diflunisal vs acetaminophen with codeine.
    The Journal of family practice, 1986, Volume: 23, Issue:2

    Topics: Acetaminophen; Acute Disease; Adult; Back Pain; Clinical Trials as Topic; Codeine; Diflunisal; Drug Combinations; Drug Tolerance; Female; Humans; Male; Pain; Prospective Studies; Random Allocation; Salicylates; Sprains and Strains

1986
Comparison of diflunisal and acetaminophen with codeine in the treatment of initial or recurrent acute low back strain.
    Clinical therapeutics, 1986, Volume: 9 Suppl C

    Topics: Acetaminophen; Adult; Back Pain; Clinical Trials as Topic; Codeine; Diflunisal; Drug Combinations; Drug Tolerance; Humans; Middle Aged; Random Allocation; Recurrence; Salicylates; Sprains and Strains

1986
The pain intensity at analgesic intake, and the efficacy of diflunisal in single doses and effervescent acetaminophen in single and repeated doses.
    Pharmacotherapy, 1988, Volume: 8, Issue:3

    Topics: Acetaminophen; Adult; Clinical Trials as Topic; Diflunisal; Female; Humans; Male; Pain; Salicylates; Tooth, Impacted

1988
Comparison of diflunisal and acetaminophen with codeine in the management of grade 2 ankle sprain.
    Clinical therapeutics, 1986, Volume: 8, Issue:5

    Topics: Acetaminophen; Adult; Ankle Injuries; Codeine; Diflunisal; Drug Combinations; Edema; Female; Humans; Male; Middle Aged; Pain; Prospective Studies; Random Allocation; Salicylates; Sprains and Strains

1986
Postoperative pain control for outpatient oral surgery.
    International journal of oral and maxillofacial surgery, 1987, Volume: 16, Issue:3

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Codeine; Diflunisal; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Random Allocation; Salicylates; Tooth Extraction; Tooth, Impacted

1987
Paracetamol and diflunisal for pain relief following third molar surgery in Hong Kong Chinese.
    International journal of oral and maxillofacial surgery, 1987, Volume: 16, Issue:5

    Topics: Acetaminophen; Adult; China; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Hong Kong; Humans; Male; Molar, Third; Pain, Postoperative; Placebos; Random Allocation; Salicylates; Tooth Extraction

1987
Comparison of diflunisal and acetaminophen with codeine in the treatment of mild to moderate pain due to strains and sprains.
    Clinical therapeutics, 1986, Volume: 8, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Athletic Injuries; Clinical Trials as Topic; Codeine; Diflunisal; Drug Combinations; Humans; Male; Pain; Random Allocation; Salicylates; Sprains and Strains

1986
Efficacy of diflunisal versus acetaminophen with codeine in controlling mild to moderate pain after arthroscopy.
    Clinical therapeutics, 1986, Volume: 8, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Arthroscopy; Codeine; Diflunisal; Drug Combinations; Drug Evaluation; Female; Humans; Knee Injuries; Male; Middle Aged; Pain; Random Allocation; Salicylates

1986
Chronic low back pain: a comparison of diflunisal with paracetamol.
    The New Zealand medical journal, 1982, May-12, Volume: 95, Issue:707

    Topics: Acetaminophen; Adult; Aged; Back Pain; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Humans; Middle Aged; Random Allocation; Salicylates

1982
Review of ibuprofen for osteoarthritis.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin

1984
Evaluation of the analgetic effect of diflunisal in patients with severe radicular pain.
    Journal of the Oslo city hospitals, 1981, Volume: 31, Issue:11

    Topics: Acetaminophen; Back Pain; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Humans; Male; Middle Aged; Salicylates

1981
Diflunisal. A new oral analgesic with an unusually long duration of action.
    JAMA, 1982, Nov-05, Volume: 248, Issue:17

    Topics: Acetaminophen; Administration, Oral; Clinical Trials as Topic; Codeine; Delayed-Action Preparations; Diflunisal; Double-Blind Method; Drug Therapy, Combination; Humans; Pain; Salicylates; Surgery, Oral; Time Factors

1982
Comparison of the analgesic effects of diflunisal and paracetamol in the treatment of postoperative dental pain.
    International journal of clinical pharmacology research, 1996, Volume: 16, Issue:2-3

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diflunisal; Double-Blind Method; Female; Humans; Male; Pain, Postoperative; Tooth Extraction

1996
Clinical effects of diflunisal and paracetamol in impacted mandibular third molar surgery.
    Journal of Marmara University Dental Faculty, 1997, Volume: 2, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diflunisal; Double-Blind Method; Female; Humans; Male; Mandible; Molar, Third; Pain, Postoperative; Preoperative Care; Tooth, Impacted

1997
A study of the comparative efficacy of three common analgesics in the control of pain after third molar surgery under local anaesthesia.
    Australian dental journal, 2002, Volume: 47, Issue:4

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Dental; Anesthesia, Local; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chi-Square Distribution; Codeine; Cyclooxygenase Inhibitors; Diflunisal; Drug Combinations; Etodolac; Follow-Up Studies; Humans; Molar, Third; Pain Measurement; Pain, Postoperative; Statistics, Nonparametric; Tooth Extraction; Tooth, Impacted; Treatment Outcome

2002

Other Studies

27 other study(ies) available for diflunisal and acetaminophen

ArticleYear
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
    Molecular pharmacology, 1999, Volume: 55, Issue:5

    Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Pathways of hepatic glycogen formation in humans following ingestion of a glucose load in the fed state.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:6

    Topics: Acetaminophen; Adult; Blood Glucose; Carbon Radioisotopes; Diflunisal; Female; Food; Glucose; Glucuronates; Glycogen; Humans; Liver; Male

1989
Pentose pathway in human liver.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:13

    Topics: Acetaminophen; Adult; Diflunisal; Female; Glucose; Glucose-6-Phosphate; Glucosephosphates; Humans; Inactivation, Metabolic; Liver; Male; Pentose Phosphate Pathway; Ribose

1988
Analgesia following arthroscopic surgery: comparison of diflunisal and acetaminophen with codeine.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 1986, Volume: 2, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Analgesia; Codeine; Diflunisal; Drug Combinations; Female; Humans; Knee Joint; Male; Pain, Postoperative; Salicylates

1986
Prescribing analgesics.
    British dental journal, 1985, Sep-21, Volume: 159, Issue:6

    Topics: Acetaminophen; Aged; Analgesics; Anticoagulants; Aspirin; Child; Codeine; Diflunisal; Drug Hypersensitivity; Female; Humans; Ibuprofen; Mefenamic Acid; Meperidine; Pain, Postoperative; Pentazocine; Pregnancy; Tooth

1985
Effect on platelet aggregation of oral administration of 10 non-steroidal analgesics to humans.
    Scandinavian journal of haematology, 1984, Volume: 33, Issue:2

    Topics: Acetaminophen; Adult; Analgesics; Aspirin; Diclofenac; Diflunisal; Epinephrine; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Oxyphenbutazone; Piroxicam; Platelet Aggregation; Thiazines; Time Factors

1984
Peripherally acting analgesics.
    The American journal of medicine, 1984, Sep-10, Volume: 77, Issue:3A

    Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Aspirin; Diflunisal; Fenoprofen; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Pain; Primary Health Care

1984
Nonopioid analgesics for patients with dental pain.
    Dental clinics of North America, 1984, Volume: 28, Issue:3

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Kinetics; Mefenamic Acid

1984
Multiple sites on prostaglandin cyclooxygenase are determinants in the action of nonsteroidal antiinflammatory agents.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:4

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Diflunisal; Indomethacin; Ketoprofen; Male; Rats; Salicylates; Stomach Ulcer; Structure-Activity Relationship

1981
Comparison of diflunisal and paracetamol in the management of pain following wisdom teeth removal.
    British dental journal, 1982, Jan-05, Volume: 152, Issue:1

    Topics: Acetaminophen; Adult; Aged; Diflunisal; Double-Blind Method; Female; Humans; Male; Middle Aged; Molar, Third; Pain, Postoperative; Salicylates; Time Factors; Tooth Extraction; Tooth, Impacted

1982
Post-anaesthetic dental extraction analgesia: a comparison of paracetamol, codeine, caffeine (Solpadeine) and diflunisal (Dolobid).
    The British journal of oral surgery, 1982, Volume: 20, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, General; Caffeine; Codeine; Diflunisal; Drug Combinations; Female; Humans; Male; Middle Aged; Pain, Postoperative; Salicylates; Tooth Extraction

1982
Diflunisal (Dolobid).
    The Medical letter on drugs and therapeutics, 1982, Aug-20, Volume: 24, Issue:616

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dextropropoxyphene; Diflunisal; Humans; Salicylates

1982
Glucuronidation of R- and S-ketoprofen, acetaminophen, and diflunisal by liver microsomes of adjuvant-induced arthritic rats.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:1

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chromatography, High Pressure Liquid; Diflunisal; Glucuronates; Ketoprofen; Male; Microsomes, Liver; Rats; Rats, Wistar

1999
Simultaneous determination of some multicomponent dosage forms by quantitative thin layer chromatography densitometric method.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 20, Issue:4

    Topics: Acetaminophen; Caffeine; Chlorzoxazone; Chromatography, Thin Layer; Densitometry; Diflunisal; Dosage Forms; Naproxen; Pharmaceutical Preparations; Solvents; Theophylline

1999
The advantages and limitations of the analgesics available for control of postoperative pain after a dental procedure.
    SAAD digest, 2013, Volume: 29

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Codeine; Cyclooxygenase 2 Inhibitors; Dental Care; Diclofenac; Diflunisal; Drug Combinations; Humans; Ibuprofen; Narcotics; Oral Surgical Procedures; Pain, Postoperative; Tramadol

2013
Nonsteroidal Anti-inflammatory Drugs (NSAIDS) Inhibit the Growth and Reproduction of Chaetomium globosum and Other Fungi Associated with Water-Damaged Buildings.
    Mycopathologia, 2017, Volume: 182, Issue:11-12

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Aspergillus; Aspirin; Cell Proliferation; Chaetomium; Diclofenac; Diflunisal; Fusarium; Germination; Humans; Ibuprofen; Lung Diseases, Fungal; Microbial Sensitivity Tests; Mycoses; Stachybotrys

2017