difloxacin has been researched along with norfloxacin in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (65.38) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koga, H; Ohta, M | 1 |
| Domagala, JM; Heifetz, CL; Hutt, MP; Mich, TF; Nichols, JB; Solomon, M; Worth, DF | 1 |
| Chu, DT; Fernandes, PB; Maleczka, RE; Nordeen, CW; Pernet, AG | 1 |
| Chu, DT; Claiborne, AK; Fernandes, PB; Maleczka, RE; Nordeen, CW; Pernet, AG; Pihuleac, E | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Antón-Fos, GM; Duart, MJ; Mut-Ronda, S; Salabert-Salvador, MT | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Ayers, LW; Barry, AL; Gavan, TL; Gerlach, EH; Jones, RN; Thornsberry, C | 1 |
| Smith, SM | 1 |
| Barry, AL; Jones, RN; Thornsberry, C | 1 |
| Bellin, EY; Chow, RT; Dougherty, TJ; Fraimow, HS; Miller, MH | 1 |
| Bailer, R; Chu, DT; Fernandes, PB; Hanson, CW; Stamm, JM; Vojtko, C | 1 |
| Liu, S; Meyer, RD | 1 |
| Ballard, RC; Fehler, G; Koornhof, HJ; Liebowitz, LD; Saunders, J | 1 |
| Habiyaremye, I; Vandepitte, J; Verbist, L | 1 |
| Verbist, L | 1 |
| Fernandes, PB; Swanson, RN | 1 |
| Deforges, L; Duval, J; Le Van Thoi, J; Soussy, CJ | 1 |
| King, A; Phillips, I | 1 |
| Bower, RR; Chu, DT; Fernandes, PB; Jarvis, KP; Ramer, NR; Shipkowitz, N | 1 |
| Donato, JB; Joseph, WS; LeFrock, JL; Smith, BR; Weber, SJ | 1 |
| Phillips, I; Power, EG | 1 |
| Barbosa, J; Barrón, D; Jiménez-Lozano, E | 1 |
| Chen, X; Hua, H; Ji, C; Lin, X; Liu, Y; Tang, S; Yue, Z | 1 |
| Dube, S; Moema, D; Nindi, MM | 1 |
| Companyó, R; Guiteras, J; Jiménez, V | 1 |
26 other study(ies) available for difloxacin and norfloxacin
| Article | Year |
|---|---|
Three-dimensional structure-activity relationships and receptor mapping of N1-substituents of quinolone antibacterials.
Topics: 4-Quinolones; Anti-Infective Agents; Computer Simulation; Escherichia coli; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Molecular Structure; Receptors, Drug; Software; Structure-Activity Relationship | 1991 |
1-Substituted 7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8- difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. New quantitative structure-activity relationships at N1 for the quinolone antibacterials.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Carboxylic Acids; Chemical Phenomena; Chemistry; Mice; Microbial Sensitivity Tests; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1988 |
Synthesis and structure-activity relationship of 1-aryl-6,8-difluoroquinolone antibacterial agents.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Female; Fluorine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Microbial Sensitivity Tests; Quinolines; Spectrophotometry, Infrared; Structure-Activity Relationship | 1987 |
Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents.
Topics: Acinetobacter; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Ciprofloxacin; Enterobacter; Escherichia coli; Female; Fluorine; Fluoroquinolones; Klebsiella pneumoniae; Mice; Norfloxacin; Pefloxacin; Piperazines; Pseudomonas aeruginosa; Quinolines; Staphylococcus; Streptococcus; Structure-Activity Relationship | 1985 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Search compounds with antimicrobial activity by applying molecular topology to selected quinolones.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Discriminant Analysis; Drug Design; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones | 2003 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
In vitro activity of the aryl-fluoroquinolones A-56619 and A-56620 and evaluation of disk susceptibility tests.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Microbial Sensitivity Tests; Norfloxacin; Piperazines; Quinolines; Staphylococcus; Streptococcus | 1986 |
In vitro comparison of A-56619, A-56620, amifloxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Methicillin; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Penicillin Resistance; Piperazines; Quinolines; Staphylococcus aureus | 1986 |
In vitro evaluation of A-56619 and A-56620, two new quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Bacteria, Anaerobic; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Piperazines; Quinolines | 1986 |
Association between early inhibition of DNA synthesis and the MICs and MBCs of carboxyquinolone antimicrobial agents for wild-type and mutant [gyrA nfxB(ompF) acrA] Escherichia coli K-12.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Mutation; Norfloxacin | 1988 |
In vitro evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones.
Topics: Anti-Infective Agents; Aztreonam; Bacteria; Cefotaxime; Ciprofloxacin; Drug Combinations; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Gentamicins; Haemophilus influenzae; Half-Life; Humans; Imipenem; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Penicillins; Piperacillin; Piperazines; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus; Streptococcus; Thienamycins | 1986 |
In vitro activity of aryl fluoroquinolones, Abbott 56619 and Abbott 56620, compared to ciprofloxacin, norfloxacin and beta-lactams versus multidrug-resistant Enterobacteriaceae and Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Pseudomonas aeruginosa | 1986 |
In vitro activity of A-56619 (difloxacin), A-56620, and other new quinolone antimicrobial agents against genital pathogens.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Ciprofloxacin; Female; Fluoroquinolones; Gardnerella vaginalis; Genitalia; Haemophilus; Haemophilus ducreyi; Humans; Male; Microbial Sensitivity Tests; Mycoplasma; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Oxazines; Ureaplasma | 1986 |
[Comparative in vitro activity of 10 new 4-quinolones against enteropathogenic bacteria].
Topics: Anti-Bacterial Agents; Campylobacter fetus; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Salmonella; Shigella; Vibrio cholerae; Yersinia enterocolitica | 1987 |
Comparative in-vitro activity of Ro 23-6240, a new trifluorinated quinolone.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines | 1987 |
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones | 1988 |
[In vitro antibacterial activity of 2 new quinolones: A 56619 (difloxacin) and A 56620. Comparison with pefloxacin, ofloxacin and ciprofloxacin].
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
The comparative in-vitro activity of eight newer quinolones and nalidixic acid.
Topics: Acinetobacter; Aeromonas; Anti-Bacterial Agents; Bacteria; Bacteria, Anaerobic; Ciprofloxacin; Enoxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Pefloxacin; Quinolines | 1986 |
In vivo evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Enterobacteriaceae Infections; Escherichia coli Infections; Female; Fluoroquinolones; Half-Life; Immunosuppression Therapy; Klebsiella Infections; Mice; Norfloxacin; Piperazines; Proteus Infections; Pseudomonas Infections; Pyelonephritis; Quinolines; Salmonella Infections, Animal; Staphylococcal Infections; Streptococcal Infections | 1986 |
In vitro activity of A-56619 and A56620, two new aryl-fluoroquinolone antimicrobial agents.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Norfloxacin; Piperazines; Quinolines | 1986 |
Correlation between umuC induction and Salmonella mutagenicity assay for quinolone antimicrobial agents.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA-Directed DNA Polymerase; Enoxacin; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Gene Expression Regulation, Bacterial; Mutagenicity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Quinolones; Salmonella typhimurium; SOS Response, Genetics; Species Specificity | 1993 |
Electrophoretic behaviour of quinolones in capillary electrophoresis. Effect of pH and evaluation of ionization constants.
Topics: Anti-Infective Agents; Chemical Phenomena; Chemistry, Physical; Ciprofloxacin; Electrophoresis, Capillary; Fluoroquinolones; Hydrogen-Ion Concentration; Ions; Mathematics; Models, Chemical; Molecular Structure; Norfloxacin; Quinolones; Solutions; Water | 1999 |
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
Development of a dispersive liquid-liquid microextraction method for the determination of fluoroquinolones in chicken liver by high performance liquid chromatography.
Topics: Animals; Anti-Bacterial Agents; Chickens; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Limit of Detection; Liquid Phase Microextraction; Liver; Norfloxacin; Regression Analysis; South Africa | 2012 |
Analysis of quinolone antibiotics in eggs: preparation and characterization of a raw material for method validation and quality control.
Topics: Anti-Bacterial Agents; Chromatography, Liquid; Ciprofloxacin; Eggs; Enrofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Oxolinic Acid; Quality Control; Quinolones; Reproducibility of Results | 2012 |