Page last updated: 2024-09-05

diflomotecan and sn 38

diflomotecan has been researched along with sn 38 in 1 studies

Compound Research Comparison

Studies
(diflomotecan)
Trials
(diflomotecan)
Recent Studies (post-2010)
(diflomotecan)
Studies
(sn 38)
Trials
(sn 38)
Recent Studies (post-2010) (sn 38)
174385143

Protein Interaction Comparison

ProteinTaxonomydiflomotecan (IC50)sn 38 (IC50)
DNA topoisomerase 1Homo sapiens (human)3.25
DNA topoisomerase 1Mus musculus (house mouse)4
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.176

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, Q; Lu, W; Wang, L1

Reviews

1 review(s) available for diflomotecan and sn 38

ArticleYear
Evolution in medicinal chemistry of E-ring-modified Camptothecin analogs as anticancer agents.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Topoisomerase I Inhibitors

2013