diflomotecan has been researched along with n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide in 1 studies
| Studies (diflomotecan) | Trials (diflomotecan) | Recent Studies (post-2010) (diflomotecan) | Studies (n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide) | Trials (n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide) | Recent Studies (post-2010) (n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide) |
|---|---|---|---|---|---|
| 17 | 4 | 3 | 149 | 13 | 63 |
| Protein | Taxonomy | diflomotecan (IC50) | n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide (IC50) |
|---|---|---|---|
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | 0.007 | |
| Carbonic anhydrase 1 | Homo sapiens (human) | 0.031 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 0.011 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 0.007 | |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | 0.007 | |
| Carbonic anhydrase 4 | Bos taurus (cattle) | 0.065 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beijnen, JH; Cendrós, JM; Friberg, LE; Huitema, AD; Karlsson, MO; Keizer, RJ; Obach, R; Peraire, C; Schellens, JH; Soto, E; Trocóniz, IF; Wanders, J | 1 |
1 trial(s) available for diflomotecan and n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide
| Article | Year |
|---|---|
Predictive ability of a semi-mechanistic model for neutropenia in the development of novel anti-cancer agents: two case studies.
Topics: Adult; Aged; Antineoplastic Agents; Camptothecin; Drug Discovery; Female; Humans; Leukocyte Count; Male; Middle Aged; Models, Biological; Neutropenia; Predictive Value of Tests; Sulfonamides; Treatment Outcome | 2011 |