difebarbamate, febarbamate, phenobarbital drug combination has been researched along with mephenytoin in 1 studies
| Studies (difebarbamate, febarbamate, phenobarbital drug combination) | Trials (difebarbamate, febarbamate, phenobarbital drug combination) | Recent Studies (post-2010) (difebarbamate, febarbamate, phenobarbital drug combination) | Studies (mephenytoin) | Trials (mephenytoin) | Recent Studies (post-2010) (mephenytoin) |
|---|---|---|---|---|---|
| 26 | 6 | 1 | 580 | 35 | 32 |
| Protein | Taxonomy | difebarbamate, febarbamate, phenobarbital drug combination (IC50) | mephenytoin (IC50) |
|---|---|---|---|
| Cytochrome P450 2C19 | Homo sapiens (human) | 1.185 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horsmans, Y; Lannes, D; Larrey, D; Pessayre, D | 1 |
1 other study(ies) available for difebarbamate, febarbamate, phenobarbital drug combination and mephenytoin
| Article | Year |
|---|---|
Possible association between poor metabolism of mephenytoin and hepatotoxicity caused by Atrium, a fixed combination preparation containing phenobarbital, febarbamate and difebarbamate.
Topics: Adult; Aged; Aged, 80 and over; Barbiturates; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Humans; Hydroxylation; Liver; Male; Mephenytoin; Middle Aged; Oxidation-Reduction; Phenobarbital; Prospective Studies | 1994 |