diethylstilbestrol-monoglucuronide has been researched along with fosfestrol* in 2 studies
2 other study(ies) available for diethylstilbestrol-monoglucuronide and fosfestrol
| Article | Year |
|---|---|
[Direct approximation of plasma concentration time curves of 3-diethylstilbestrol monoglucuronide following oral and intravenous administration of fosfestrol].
Drugs undergoing presystemic elimination, enterohepatic recycling and multiple biotransformation show atypical plasma level curves with considerable deviations. The data are approximated by modified exponential functions, whose "intrinsic" properties anticipate the overall behaviour of the experimental data, even in complicated cases. The initial parameter estimates can be calculated directly from the experimental data. Topics: Administration, Oral; Antineoplastic Agents; Diethylstilbestrol; Humans; Injections, Intravenous; Kinetics | 1986 |
[Plasma levels of fosfestrol and its monophosphate, of diethylstilbestrol and its monoglucuronide following intravenous administration in patients with metastatic prostatic carcinoma].
A homogeneous ion pair extraction technique enables the nearly quantitative isolation of fosfestrol (1) (Honvan) and up till now of three of its metabolites from the plasma of patients suffering from metastatic prostata cancer. The detection occurs by HPLC with UV-detector. The range of detection is in the lower microgram range. It is the first time that plasma levels of 1 and its monophosphate (2) can be measured. Topics: Aged; Antineoplastic Agents; Chromatography, High Pressure Liquid; Diethylstilbestrol; Humans; Injections, Intravenous; Male; Neoplasm Metastasis; Prostatic Neoplasms; Stereoisomerism | 1984 |