diethylstilbestrol and ketoconazole

diethylstilbestrol has been researched along with ketoconazole in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19908 (40.00)18.7374
1990's2 (10.00)18.2507
2000's2 (10.00)29.6817
2010's5 (25.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Huben, RP1
Balin, C; Fleyfel, M; Leroy, B; Marecaux, O; Plouvier, F; Scherpereel, P1
Cummings, KB; Havlin, KH; Jordan, VC; Lange, PH; Messing, EM; Trump, DL1
Hogan, T; Jubelirer, SJ1
Waxman, J1
Dunzendorfer, U; Oelschläger, H; Rothley, D1
Babaian, RJ; Johnson, DE; Tenney, D; von Eschenbach, AC; Wishnow, KI1
Albert, J; Geller, J1
Bloom, SR; Williams, G1
Ahn, B; Baek, IJ; Choo, YK; Hong, JT; Jin, Y; Kim, MR; Lee, BJ; Lee, SR; Nam, SY; Yon, JM; Yun, YW1
Colleoni, S; Crotti, G; Franciosi, F; Galli, C; Lazzari, G; Lodde, V; Luciano, AM; Modina, SC; Tessaro, I1
Boberg, J; Christiansen, S; Draskau, MK; Johansson, HKL; Svingen, T1
Dong, Y; Ge, RS; Li, H; Shi, L; Tang, L; Tang, Y; Ying, Y1
Boberg, J; Chalmel, F; Chan Sock Peng, E; Darde, TA; Draskau, MK; Evrard, B; Johansson, HKL; Kugathas, I; Mazaud-Guittot, S; Rolland, AD; Svingen, T; Toupin, M1
Bloomer, WD; Papadopoulou, MV; Rosenzweig, HS1

Reviews

3 review(s) available for diethylstilbestrol and ketoconazole

ArticleYear
[Favorable outcome of neoplastic disseminated intravascular coagulation treated with ketoconazole and estrogen derivative].
    Annales francaises d'anesthesie et de reanimation, 1991, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Biopsy, Needle; Blood Coagulation Tests; Diethylstilbestrol; Disseminated Intravascular Coagulation; Humans; Ketoconazole; Male; Middle Aged; Prostatic Neoplasms

1991
High dose ketoconazole for the treatment of hormone refractory metastatic prostate carcinoma: 16 cases and review of the literature.
    The Journal of urology, 1989, Volume: 142, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Diethylstilbestrol; Humans; Ketoconazole; Male; Middle Aged; Orchiectomy; Prognosis; Prostatic Neoplasms

1989
Hormonal aspects of prostatic cancer: a review.
    Journal of the Royal Society of Medicine, 1985, Volume: 78, Issue:2

    Topics: Adrenalectomy; Castration; Cyproterone; Diethylstilbestrol; Hormones; Humans; Hypophysectomy; Ketoconazole; Male; Middle Aged; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Receptors, Cell Surface; Tamoxifen; Testosterone

1985

Trials

1 trial(s) available for diethylstilbestrol and ketoconazole

ArticleYear
Hormone therapy of prostatic bone metastases.
    Advances in experimental medicine and biology, 1992, Volume: 324

    Topics: Actuarial Analysis; Androgen Antagonists; Bone Neoplasms; Combined Modality Therapy; Diethylstilbestrol; Estrogens; Flutamide; Gonadotropin-Releasing Hormone; Goserelin; Humans; Ketoconazole; Leuprolide; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Remission Induction; Spironolactone; Survival Rate

1992

Other Studies

16 other study(ies) available for diethylstilbestrol and ketoconazole

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Management of metastatic prostatic carcinoma.
    Drug and therapeutics bulletin, 1986, Nov-03, Volume: 24, Issue:22

    Topics: Adrenalectomy; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Diethylstilbestrol; Gonadotropin-Releasing Hormone; Humans; Hypophysectomy; Ketoconazole; Male; Orchiectomy; Palliative Care; Prostatic Neoplasms

1986
High-dose ketoconazole in advanced hormone-refractory prostate cancer: endocrinologic and clinical effects.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:8

    Topics: Acid Phosphatase; Aged; Aged, 80 and over; Androstenedione; Antigens, Neoplasm; Biomarkers, Tumor; Diethylstilbestrol; Drug Evaluation; Humans; Hydrocortisone; Ketoconazole; Male; Middle Aged; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Testicular Hormones; Testosterone

1989
[Drug therapy of metastasizing prostate carcinoma with special reference to the bioavailability of fosfestrol after oral administration].
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:10

    Topics: Administration, Oral; Aged; Androgen Antagonists; Antineoplastic Agents; Biological Availability; Biotransformation; Carcinoma; Chemical Phenomena; Chemistry; Diethylstilbestrol; Estramustine; Estrogens; Humans; Ketoconazole; Male; Middle Aged; Neoplasm Metastasis; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Protein Binding

1988
Ketoconazole therapy for hormonally refractive metastatic prostate cancer.
    Urology, 1988, Volume: 31, Issue:2

    Topics: Aged; Aged, 80 and over; Androgens; Bone Neoplasms; Carcinoma; Combined Modality Therapy; Diethylstilbestrol; Humans; Ketoconazole; Male; Middle Aged; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms

1988
Effects of castration compared with total androgen blockade on tissue dihydrotestosterone (DHT) concentration in benign prostatic hyperplasia (BPH).
    Urological research, 1987, Volume: 15, Issue:3

    Topics: Androgen Antagonists; Castration; Combined Modality Therapy; Diethylstilbestrol; Dihydrotestosterone; Drug Combinations; Humans; Hyperplasia; Ketoconazole; Male; Megestrol; Megestrol Acetate; Orchiectomy; Prostate; Tissue Distribution

1987
Treatment of advanced carcinoma of the prostate.
    British medical journal (Clinical research ed.), 1984, Sep-08, Volume: 289, Issue:6445

    Topics: Castration; Combined Modality Therapy; Diethylstilbestrol; Humans; Ketoconazole; Male; Prostatic Neoplasms

1984
Effects of endocrine disrupting chemicals on expression of phospholipid hydroperoxide glutathione peroxidase mRNA in rat testes.
    Journal of veterinary science, 2007, Volume: 8, Issue:3

    Topics: Androgen Antagonists; Animals; Diethylhexyl Phthalate; Diethylstilbestrol; Endocrine Disruptors; Estrogens, Non-Steroidal; Flutamide; Glutathione Peroxidase; Histocytochemistry; Ketoconazole; Male; Phenols; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spermatogenesis; Testis; Testosterone

2007
Transferability and inter-laboratory variability assessment of the in vitro bovine oocyte fertilization test.
    Reproductive toxicology (Elmsford, N.Y.), 2015, Volume: 51

    Topics: Acetoacetates; Animals; Benzo(a)pyrene; Busulfan; Cadmium Chloride; Cattle; Cycloheximide; Diethylstilbestrol; Fertilization in Vitro; In Vitro Oocyte Maturation Techniques; Ketoconazole; Laboratories; Mifepristone; Oocytes; Reproducibility of Results

2015
Classical toxicity endpoints in female rats are insensitive to the human endocrine disruptors diethylstilbestrol and ketoconazole.
    Reproductive toxicology (Elmsford, N.Y.), 2021, Volume: 101

    Topics: Anal Canal; Animals; Diethylstilbestrol; Endocrine Disruptors; Female; Genitalia; Humans; Ketoconazole; Male; Maternal-Fetal Exchange; Nipples; Pregnancy; Rats, Sprague-Dawley; Sexual Maturation; Toxicity Tests

2021
Chemicals of environmental concern as inhibitors of human placental 3β-hydroxysteroid dehydrogenase 1 and aromatase: Screening and docking analysis.
    Chemico-biological interactions, 2022, Dec-01, Volume: 368

    Topics: Aromatase; Aromatase Inhibitors; Cell Line, Tumor; Diethylstilbestrol; Environmental Pollutants; Estradiol; Female; Humans; Ketoconazole; Multienzyme Complexes; Phenols; Pregnancy; Progesterone Reductase; Steroid Isomerases; Zearalenone

2022
Transcriptional profiling of the developing rat ovary following intrauterine exposure to the endocrine disruptors diethylstilbestrol and ketoconazole.
    Archives of toxicology, 2023, Volume: 97, Issue:3

    Topics: Animals; Diethylstilbestrol; Endocrine Disruptors; Female; Humans; Ketoconazole; Mice; Ovary; Potassium Channels, Voltage-Gated; Pregnancy; Rats; Reproduction

2023
The antitubercular activity of various nitro(triazole/imidazole)-based compounds.
    Bioorganic & medicinal chemistry, 2017, 11-01, Volume: 25, Issue:21

    Topics: Animals; Antitubercular Agents; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Humans; Imidazoles; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Structure-Activity Relationship; Triazoles

2017