diethylnitrosamine has been researched along with transforming growth factor beta in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (23.08) | 18.2507 |
| 2000's | 8 (30.77) | 29.6817 |
| 2010's | 10 (38.46) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Jirtle, RL; Meyer, SA | 1 |
| Stenius, U | 1 |
| Goldsworthy, TL; Harden, R; Jirtle, RL; Mills, J; Moser, GJ; Standeven, AM; Wolf, DC | 1 |
| Factor, VM; Jensen, MR; Kao, CY; Santoni-Rugiu, E; Thorgeirsson, SS; Woitach, JT | 1 |
| Fukushima, S; Funae, Y; Hagiwara, A; Ichihara, T; Imaoka, S; Kitano, M; Matsuda, T; Shirai, T; Tamano, S; Wanibuchi, H | 1 |
| Hyun, BH; Kim, SJ; Lee, MS; Lim, IK; Park, SC; Park, TJ; Song, KY | 1 |
| Konishi, Y; Murata, N; Sasaki, Y; Tsujiuchi, T; Tsutsumi, M | 1 |
| Ruan, Y; Wu, Z; Zheng, M | 1 |
| Anzano, M; Factor, VM; Flanders, K; Hahm, KB; Haines, DC; Im, YH; Jang, JJ; Kim, HT; Kim, IY; Kim, SJ; Sizeland, A; Thorgeirsson, SS | 1 |
| Biju, MP; Paulose, CS; Pyroja, S; Rajeshkumar, NV | 1 |
| Lim, IK | 1 |
| Bollito, E; Tessitore, L | 1 |
| Knudsen, ES; Mayhew, CN; Peng, L; Puga, A; Schnekenburger, M | 1 |
| Chen, BH; Huang, KW; Huang, YC; Hwang, LH; Lee, PH; Tai, KF | 1 |
| Kakehashi, A; Tajiri, M; Wanibuchi, H; Wei, M; Xie, XL; Yamano, S | 1 |
| Chen, C; Ding, J; Feng, GS; Han, T; Huang, L; Li, Z; Ning, BF; Sun, W; Wang, C; Wang, HY; Wen, W; Wu, K; Wu, MC; Xie, WF; Yang, W | 1 |
| Chang, Z; Chu, ES; Go, MY; Heuchel, R; Lan, HY; Man, K; Mok, MT; Sung, JJ; Wang, J; Yu, J; Zhao, J | 1 |
| He, S; Hu, X; Jiang, J; Rui, W; Wu, C; Yang, Y; Zhang, X | 1 |
| Abd El-Aziz, EA; Abd El-Aziz, HO; Abd El-Ghany, AA; Abdel Aziz, MA; Abouzied, MM; Ahmed, NS; Eltahir, HM | 1 |
| Boye, A; He, S; Jiang, Y; Kan, H; Wu, C; Yang, X; Yang, Y | 1 |
| He, H; Jing, Y; Li, R; Lu, J; Shen, Y; Wang, Z; Wei, L; Wei, Y; Yang, T; Yuan, J; Zhao, Q | 1 |
| Fouad, H; Hussein, RE; Mahfouz, S; Rashed, LA; Saad El-Din, S | 1 |
| Daujat-Chavanieu, M; Kot, M | 1 |
| El-Sonbaty, SM; Mansour, SZ; Moawed, FS | 1 |
| Ji, SD; Kim, EH; Lee, DY; Son, JG; Song, MY; Yun, SM | 1 |
| Feng, J; Fu, Q; Guo, J; Ling, B; Ning, K; Wang, J; Wu, B; Xiu, G; Xu, J | 1 |
26 other study(ies) available for diethylnitrosamine and transforming growth factor beta
| Article | Year |
|---|---|
Liver tumor promotion: effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-beta 1 expression.
Topics: Animals; Binding, Competitive; Cell Transformation, Neoplastic; Diethylnitrosamine; Epidermal Growth Factor; Liver; Liver Neoplasms, Experimental; Phenobarbital; Protein Kinase C; Rats; Signal Transduction; Transforming Growth Factor beta; Tumor Cells, Cultured | 1991 |
Different inhibition of DNA synthesis by transforming growth factor beta and phenobarbital on GST-P-positive and GST-P-negative hepatocytes.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Diethylnitrosamine; DNA; Female; Glutathione Transferase; Liver; Phenobarbital; Rats; Transforming Growth Factor beta | 1993 |
Cell proliferation and regulation of negative growth factors in mouse liver foci.
Topics: Air Pollutants; Animals; Biomarkers, Tumor; Carcinogens; Cell Division; Diet; Diethylnitrosamine; Ethinyl Estradiol; Female; Gasoline; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred Strains; Mitotic Index; Models, Biological; Mutagens; Precancerous Conditions; Receptor, IGF Type 2; Transforming Growth Factor beta | 1996 |
Constitutive expression of mature transforming growth factor beta1 in the liver accelerates hepatocarcinogenesis in transgenic mice.
Topics: Animals; Blotting, Northern; Diethylnitrosamine; Gene Expression Regulation, Neoplastic; Genes, myc; Immunohistochemistry; Liver Neoplasms, Experimental; Mice; Mice, Transgenic; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Up-Regulation | 1997 |
Presence of a threshold for promoting effects of phenobarbital on diethylnitrosamine-induced hepatic foci in the rat.
Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dose-Response Relationship, Drug; Glutathione Transferase; Hepatectomy; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Phenobarbital; Rats; Rats, Inbred F344; Transforming Growth Factor alpha; Transforming Growth Factor beta | 1998 |
Regulation of selection of liver nodules initiated with N-nitrosodiethylamine and promoted with nodularin injections in fischer 344 male rats by reciprocal expression of transforming growth factor-beta1 and its receptors.
Topics: Alkylating Agents; Animals; Blotting, Northern; Diethylnitrosamine; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Hyperplasia; Immunohistochemistry; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Peptides, Cyclic; Precancerous Conditions; Rats; Rats, Inbred F344; Receptors, Transforming Growth Factor beta; Time Factors; Transforming Growth Factor beta | 1999 |
Alterations of the transforming growth factor-beta signaling pathway in hepatocellular carcinomas induced endogenously and exogenously in rats.
Topics: Alkylating Agents; Animals; Carcinoma, Hepatocellular; Choline; Diethylnitrosamine; DNA-Binding Proteins; Liver Neoplasms; Male; Polymorphism, Single-Stranded Conformational; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad2 Protein; Smad4 Protein; Trans-Activators; Transforming Growth Factor beta | 2001 |
[Correlation study of TGF beta expression in diethylnitrosamine-induced rat liver cancer and mast cells in its vicinity].
Topics: Animals; Cell Division; Diethylnitrosamine; Dose-Response Relationship, Drug; Liver Neoplasms, Experimental; Male; Mast Cells; Rats; Transforming Growth Factor beta | 2000 |
Heterozygous mice for the transforming growth factor-beta type II receptor gene have increased susceptibility to hepatocellular carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Female; Gene Dosage; Genes, cdc; Genetic Predisposition to Disease; Heterozygote; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Pregnancy; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Enhanced GABA(B) receptor in neoplastic rat liver: induction of DNA synthesis by baclofen in hepatocyte cultures.
Topics: Alkylating Agents; Animals; Baclofen; Cell Division; Cells, Cultured; Diethylnitrosamine; DNA; Dose-Response Relationship, Drug; GABA Agonists; Hepatocytes; Kinetics; Lead; Liver; Male; Mitogens; Nitrates; Protein Binding; Rats; Rats, Wistar; Receptors, GABA-B; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Up-Regulation | 2002 |
Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fisher 344 male rats [Mechanisms of Ageing and Development 123 (2002) 1665-1680].
Topics: Aging; Alkylating Agents; Animals; Carcinoma, Hepatocellular; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p16; Diethylnitrosamine; Disease Models, Animal; DNA Damage; Liver Cirrhosis; Liver Neoplasms; Male; Peptides, Cyclic; Rats; Rats, Inbred F344; Retinoblastoma Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Suppressor Protein p53 | 2003 |
Early induction of TGF-beta1 through a fasting-re-feeding regimen promotes liver carcinogenesis by a sub-initiating dose of diethylnitrosamine.
Topics: 2-Acetylaminofluorene; Animals; Apoptosis; bcl-2-Associated X Protein; Carbon Tetrachloride; Carcinogens; Diethylnitrosamine; Eating; Fasting; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2006 |
Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors.
Topics: Animals; Base Sequence; Carcinogens; CpG Islands; Diethylnitrosamine; Disease Models, Animal; Disease Progression; DNA Methylation; DNA, Complementary; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Liver Neoplasms; Mice; Mice, Knockout; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Retinoblastoma Protein; Transforming Growth Factor beta | 2008 |
Dual therapeutic effects of interferon-alpha gene therapy in a rat hepatocellular carcinoma model with liver cirrhosis.
Topics: Animals; Apoptosis; Carcinogens; Cell Proliferation; Diethylnitrosamine; Genetic Therapy; Interferon-alpha; Liver Cirrhosis; Liver Neoplasms, Experimental; Rats; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta | 2008 |
2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) promotes mouse hepatocarcinogenesis by activating transforming growth factor-β and Wnt/β-catenin signaling pathways.
Topics: Animals; beta Catenin; Blotting, Western; Body Weight; Carcinoma, Hepatocellular; Cell Adhesion; Cell Transformation, Neoplastic; Diethylnitrosamine; Dose-Response Relationship, Drug; Drinking; Eating; Hepatectomy; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Mice; Organ Size; Quinolines; Time Factors; Transforming Growth Factor beta; Wnt Proteins; Wnt Signaling Pathway | 2012 |
Hepatic transforming growth factor beta gives rise to tumor-initiating cells and promotes liver cancer development.
Topics: AC133 Antigen; Animals; Antigens, CD; Antigens, Differentiation; Antigens, Neoplasm; Biomarkers, Tumor; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Diethylnitrosamine; Epithelial Cell Adhesion Molecule; Glycoproteins; Humans; Liver; Liver Cirrhosis; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Neoplastic Stem Cells; Peptides; Pluripotent Stem Cells; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Wistar; STAT3 Transcription Factor; Thy-1 Antigens; TOR Serine-Threonine Kinases; Transforming Growth Factor beta | 2012 |
Inhibitory role of Smad7 in hepatocarcinogenesis in mice and in vitro.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Proliferation; Diethylnitrosamine; G1 Phase; Genes, Reporter; Genetic Predisposition to Disease; Hep G2 Cells; Hepatocytes; Humans; Immunoprecipitation; Liver Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Phenotype; Primary Cell Culture; S Phase; Signal Transduction; Smad7 Protein; Time Factors; Transfection; Transforming Growth Factor beta | 2013 |
Compound Astragalus and Salvia miltiorrhiza extracts suppress hepatocarcinogenesis by modulating transforming growth factor-β/Smad signaling.
Topics: Animals; Astragalus Plant; Carcinoma, Hepatocellular; Diethylnitrosamine; Dose-Response Relationship, Drug; Gene Expression; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Neoplasm Invasiveness; Phosphorylation; Plant Extracts; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Up-Regulation | 2014 |
Curcumin ameliorate DENA-induced HCC via modulating TGF-β, AKT, and caspase-3 expression in experimental rat model.
Topics: Alanine Transaminase; Animals; Apoptosis; Caspase 3; Curcumin; Diethylnitrosamine; Disease Models, Animal; Drug Interactions; Glutamyl Aminopeptidase; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; Proto-Oncogene Proteins c-akt; Rats; Transforming Growth Factor beta | 2015 |
MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells.
Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; Diethylnitrosamine; Flavonoids; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinase Kinases; Neoplasm Invasiveness; Plasminogen Activator Inhibitor 1; Rats; Smad Proteins; Transforming Growth Factor beta | 2015 |
TGF-β regulates hepatocellular carcinoma progression by inducing Treg cell polarization.
Topics: Animals; Azabicyclo Compounds; Carcinoma, Hepatocellular; Cell Differentiation; Cell Polarity; Cell Proliferation; Diethylnitrosamine; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Forkhead Transcription Factors; Interleukin-10; Liver Neoplasms; Male; Membrane Proteins; Mice; Phosphoproteins; Receptors, Transforming Growth Factor beta; T-Lymphocytes, Regulatory; Transforming Growth Factor beta; Up-Regulation | 2015 |
Impact of Mesenchymal Stem Cells and Vitamin D on Transforming Growth Factor Beta Signaling Pathway in Hepatocellular Carcinoma in Rats
Topics: Alkylating Agents; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Diethylnitrosamine; Female; Gene Expression Regulation, Neoplastic; Liver Neoplasms, Experimental; Mesenchymal Stem Cells; Rats; Signal Transduction; Transforming Growth Factor beta; Vitamin D; Vitamins | 2018 |
Altered cytokine profile under control of the serotonergic system determines the regulation of CYP2C11 and CYP3A isoforms.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Body Weight; Cytochrome P-450 CYP3A; Cytochrome P450 Family 2; Cytokines; Diethylnitrosamine; Disease Models, Animal; Hepatic Insufficiency; Inflammation Mediators; Interleukin-1beta; Interleukin-4; Liver; Male; Organ Size; Protein Processing, Post-Translational; Rats, Wistar; RNA Processing, Post-Transcriptional; Serotonin; Signal Transduction; Steroid 16-alpha-Hydroxylase; Testosterone; Transforming Growth Factor beta | 2018 |
Gallium nanoparticles along with low-dose gamma radiation modulate TGF-β/MMP-9 expression in hepatocellular carcinogenesis in rats.
Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Caspase 3; Diethylnitrosamine; Disease Models, Animal; DNA Fragmentation; Gallium; Gamma Rays; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Matrix Metalloproteinase 9; Metal Nanoparticles; Radiation Dosage; Rats; Transforming Growth Factor beta | 2019 |
Administration of Steamed and Freeze-Dried Mature Silkworm Larval Powder Prevents Hepatic Fibrosis and Hepatocellular Carcinogenesis by Blocking TGF-β/STAT3 Signaling Cascades in Rats.
Topics: Animals; Bombyx; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; Diethylnitrosamine; Freeze Drying; Inflammation; Liver Cirrhosis; Liver Neoplasms; Male; Phosphorylation; Powders; Rats, Wistar; Signal Transduction; STAT3 Transcription Factor; Transforming Growth Factor beta | 2020 |
ADSCs-derived exosomes ameliorate hepatic fibrosis by suppressing stellate cell activation and remodeling hepatocellular glutamine synthetase-mediated glutamine and ammonia homeostasis.
Topics: Ammonia; Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Diethylnitrosamine; Exosomes; Fibrosis; Glutamate-Ammonia Ligase; Glutamine; Hepatic Stellate Cells; Homeostasis; Liver Cirrhosis; Liver Neoplasms; Mice; Stromal Cells; Transforming Growth Factor beta | 2022 |