Page last updated: 2024-08-17

diethylnitrosamine and guanine

diethylnitrosamine has been researched along with guanine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199024 (68.57)18.7374
1990's8 (22.86)18.2507
2000's2 (5.71)29.6817
2010's1 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adamson, RH; Borek, E; Gehrke, CW; Lakings, DB; Longmore, J; Mrochek, JE; Waalkes, TP1
Kerler, R; Rabes, HM; Riess, H; Rode, G; Wilhelm, R1
Balog, B; Pegg, AE1
Craig, AW; Curtin, NJ; Margison, GP; Snell, K1
Pegg, AE2
Emmelot, P; Scherer, E; Steward, AP1
Butler, WH; Fan, CY; O'Connor, PJ1
Den Engelse, L; Scherer, E; Van Den Berg, T; Vermeulen, E; Winterwerp, HH1
Boucheron, JA; Dyroff, MC; Popp, JA; Richardson, FC; Swenberg, JA1
Bailey, GS; Dashwood, RH; Fong, AT; Hendricks, JD; Lee, BC; Van Winkle, S1
Bailey, GS; Dashwood, RH; Fong, AT; Hendricks, JD; Van Winkle, S1
den Engelse, L; Jenner, AA; Scherer, E1
Barbason, H; Brumioul, D; LemaƮtre, M; Verly, WG1
Boucheron, J; Deal, F; Richardson, FC; Swenberg, JA; Tyeryar, L1
Bresil, H; Lu, LY; Lu, SX; Montesano, R; Xiao, GL1
Fong, AT; Rasmussen, RE2
Kleihues, P; von Hofe, E1
Becker, RA; Shank, RC1
Margison, GP1
Renard, A; Verly, WG1
Bedell, MA; Billings, KC; Pegg, AE; Swenberg, JA; Umbenhauer, DR1
Craddock, VM; Gash, S; Henderson, AR1
Dragan, YP; Hully, JR; Mass, MJ; Nakamura, J; Pitot, HC; Swenberg, JA1
Emura, M; Kamino, K; Mohr, U; Rajewsky, MF; Seiler, F; Thomale, J1
Ali, N; Gebhardt, R; Iatropoulos, MJ; Peterson, LA; Rivenson, A; Schulz, C; Wang, CX; Williams, GM1
Akai, H; Andoh, N; Kobayashi, Y; Konishi, Y; Nakae, D; Ohashi, K; Satoh, H; Tsutsumi, M1
Akai, H; Denda, A; Horiguchi, K; Kobayashi, Y; Konishi, Y; Nakae, D; Satoh, H; Tamura, K; Tsujiuchi, T1
Arimoto-Kobayashi, S; Hayatsu, H; Kaji, K; Sweetman, GM1
Baan, RA; Berends, F; Bergmans, A; Borsboom, Y; Lohman, PH; Luiten-Schuite, A; Mientjes, EJ; van Delft, JH; van der Wolf, E1
Emura, M; Kamino, K; Mohr, U; Seiler, F; Thomale, J1
Loeppky, RN; Park, M1
Fukushima, S; Funae, Y; Kinoshita, A; Mitsuru, F; Morimura, K; Oka, M; Puatanachokchai, R; Wanibuchi, H; Yamaguchi, S1
Chariyakornkul, A; Chewonarin, T; Jarukamjorn, K; Punvittayagul, C; Wongpoomchai, R1

Other Studies

35 other study(ies) available for diethylnitrosamine and guanine

ArticleYear
Composition, associated tissue methyltransferase activity, and catabolic end products of transfer RNA from carcinogen-induced hepatoma and normal monkey livers.
    Cancer research, 1977, Volume: 37, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Female; Guanine; Guanosine; Haplorhini; Hypoxanthines; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Pseudouridine; RNA, Neoplasm; RNA, Transfer; Thymine; tRNA Methyltransferases

1977
Alkylation of DNA and RNA by [14C]dimethylnitrosamine in hydroxyurea-synchronized regenerating rat liver.
    Cancer research, 1979, Volume: 39, Issue:10

    Topics: Alkylation; Animals; Cell Cycle; Diethylnitrosamine; DNA; Guanine; Hydroxyurea; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Nitrosamines; Rats; RNA

1979
Formation and subsequent excision of O6-ethylguanine from DNA of rat liver following administration of diethylnitrosamine.
    Cancer research, 1979, Volume: 39, Issue:12

    Topics: Alkylation; Animals; Diethylnitrosamine; DNA; Female; Guanine; In Vitro Techniques; Liver; Nitrosamines; Rats; Time Factors

1979
Effect of chronic N,N-diethylnitrosamine on the excision of O6-ethylguanine from rat liver DNA.
    British journal of cancer, 1979, Volume: 40, Issue:5

    Topics: Adenine; Alkylation; Animals; Diethylnitrosamine; DNA; DNA Repair; Guanine; Liver; Male; Nitrosamines; Rats

1979
Effect of pretreatment with other dialkylnitrosamines on excision from hepatic DNA of O6-methylguanine produced by dimethylnitrosamine.
    Chemico-biological interactions, 1978, Volume: 22, Issue:1

    Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; DNA; Guanine; Liver; Methylation; Nitrosamines; Rats; Time Factors

1978
Kinetics of formation of O6-ethylguanine in, and its removal from liver DNA of rats receiving diethylnitrosamine.
    Chemico-biological interactions, 1977, Volume: 19, Issue:1

    Topics: Animals; Diethylnitrosamine; DNA; Dose-Response Relationship, Drug; Female; Guanine; Kinetics; Liver; Nitrosamines; Rats; Time Factors

1977
Cell and tissue specific localization of O6-methylguanine in the DNA of rats given N-nitrosodimethylamine: effects of protein deficient and normal diets.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: Alkylation; Animals; Cell Nucleus; Diethylnitrosamine; DNA; Guanine; Immunohistochemistry; Kidney; Liver; Male; Protein-Energy Malnutrition; Rats; Rats, Inbred Strains; Reference Values

1989
Immunocytochemical analysis of O6-alkylguanine shows tissue specific formation in and removal from esophageal and liver DNA in rats treated with methylbenzylnitrosamine, dimethylnitrosamine, diethylnitrosamine and ethylnitrosourea.
    Cancer letters, 1989, Jul-01, Volume: 46, Issue:1

    Topics: Animals; Carcinogens; Cell Nucleus; Diethylnitrosamine; Dimethylnitrosamine; DNA Damage; DNA Repair; Esophagus; Ethylnitrosourea; Female; Guanine; Immunoenzyme Techniques; Liver; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred Strains; Substrate Specificity

1989
Biochemical and morphologic studies of heterogeneous lobe responses in hepatocarcinogenesis.
    Carcinogenesis, 1986, Volume: 7, Issue:2

    Topics: Alkylation; Animals; Carbon Radioisotopes; Carbon Tetrachloride; Cell Division; Diethylnitrosamine; gamma-Glutamyltransferase; Guanine; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Thymidine

1986
Modulation of diethylnitrosamine-induced hepatocarcinogenesis and O6-ethylguanine formation in rainbow trout by indole-3-carbinol, beta-naphthoflavone, and Aroclor 1254.
    Toxicology and applied pharmacology, 1988, Volume: 96, Issue:1

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Diethylnitrosamine; DNA; Flavonoids; Guanine; Indoles; Liver; Liver Neoplasms; Polychlorinated Biphenyls; Salmonidae; Trout

1988
Formation and persistence of ethylguanines in liver DNA of rainbow trout (Salmo gairdneri) treated with diethylnitrosamine by water exposure.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1988, Volume: 26, Issue:8

    Topics: Animals; Chromatography, High Pressure Liquid; Diethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Liver; Trout; Water

1988
Immunocytochemical studies on the formation and repair of O6-alkylguanine in rat tissues.
    IARC scientific publications, 1987, Issue:84

    Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Ethylnitrosourea; Guanine; Immunohistochemistry; Islets of Langerhans; Kidney Glomerulus; Liver; Male; Muscle, Smooth; Precancerous Conditions; Rats; Spermatogonia; Tissue Distribution

1987
Action of phenobarbital given to rats together with diethylnitrosamine on the O6-ethylguanine content of liver DNA.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:7

    Topics: Animals; Diethylnitrosamine; DNA; DNA Repair; Guanine; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains

1988
The molecular dosimetry of DNA adducts formed by continuous exposure of rats to alkylating hepatocarcinogens.
    Progress in experimental tumor research, 1987, Volume: 31

    Topics: 1,2-Dimethylhydrazine; Alkylating Agents; Animals; Carcinogens; Diethylnitrosamine; Dimethylhydrazines; DNA Damage; Guanine; Liver; Rats; Thymine

1987
[Effect of molybdenum Mo on the alkylation of DNA in the liver of rats treated with 14C-diethylnitrosamine].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1987, Volume: 9, Issue:1

    Topics: Alkylation; Animals; Carbon Radioisotopes; Diethylnitrosamine; DNA; Guanine; Liver; Male; Molybdenum; Rats

1987
DNA ethylation in hamster tissues during subchronic diethylnitrosamine administration and in the hamster trachea after acute diethylnitrosamine administration.
    Carcinogenesis, 1986, Volume: 7, Issue:9

    Topics: Alkylation; Animals; Cricetinae; Diethylnitrosamine; DNA; Guanine; Liver; Lung; Male; Mesocricetus; Trachea; Tracheal Neoplasms

1986
Comparative studies on hepatic DNA alkylation in rats by N-nitrosomethylethylamine and N-nitrosodimethylamine plus N-nitrosodiethylamine.
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:3

    Topics: Alkylation; Animals; Diethylnitrosamine; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Liver; Male; Mathematics; Rats; Rats, Inbred F344

1986
Formation and accumulation of O6-ethylguanine in DNA of enriched populations of Clara cells, alveolar type II cells, and macrophages of hamsters exposed to diethylnitrosamine.
    Toxicology, 1987, Volume: 43, Issue:3

    Topics: Alkylation; Animals; Cricetinae; Diethylnitrosamine; DNA; Guanine; Macrophages; Male; Mesocricetus; Pulmonary Alveoli

1987
Kinetics of formation and persistence of ethylguanines in DNA of rats and hamsters treated with diethylnitrosamine.
    Cancer research, 1985, Volume: 45, Issue:5

    Topics: Alkylation; Animals; Cricetinae; Diethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Kinetics; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mesocricetus; Nitrosamines; Rats; Rats, Inbred Strains; Species Specificity

1985
Chronic or acute administration of various dialkylnitrosamines enhances the removal of O6-methylguanine from rat liver DNA in vivo.
    Chemico-biological interactions, 1982, Volume: 38, Issue:2

    Topics: Animals; Chromatography, Gel; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Guanine; Liver; Male; Nitrosamines; Purines; Rats; RNA

1982
Properties of the O6-alkylguanine-DNA repair system of mammalian cells.
    IARC scientific publications, 1984, Issue:57

    Topics: Adenine; Animals; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Guanine; In Vitro Techniques; Liver; Nitroso Compounds; Rats

1984
Repair of O6-ethylguanine DNA lesions in isolated cell nuclei. Presence of the activity in the chromatin proteins.
    European journal of biochemistry, 1983, Nov-15, Volume: 136, Issue:3

    Topics: Animals; Cell Nucleus; Chemical Phenomena; Chemistry; Chromatin; Chromatography, Paper; Diethylnitrosamine; DNA Repair; Ethylnitrosourea; Guanine; Liver; Male; Rats; Rats, Inbred Strains

1983
Cell-specific differences in O6-alkylguanine DNA repair activity during continuous exposure to carcinogen.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:18

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Separation; Diethylnitrosamine; Dimethylhydrazines; DNA Repair; Guanine; Kinetics; Liver; Male; Methylhydrazines; Nitrosamines; Proteins; Rats; Rats, Inbred Strains

1982
Nature of the constitutive and induced mammalian O6-methylguanine DNA repair enzyme.
    Biochemical and biophysical research communications, 1982, Jul-30, Volume: 107, Issue:2

    Topics: Animals; Cysteine; Diethylnitrosamine; DNA Repair; Guanine; Liver; Rats; Time Factors

1982
Biochemical events during initiation of rat hepatocarcinogenesis.
    Carcinogenesis, 1994, Volume: 15, Issue:7

    Topics: Animals; Cell Division; Diethylnitrosamine; DNA; Glutathione Transferase; Guanine; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344

1994
Formation of O6-ethylguanine in spermatogonial DNA of adult Syrian golden hamster by intraperitoneal injection of diethylnitrosamine.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1995, Volume: 47, Issue:6

    Topics: Animals; Biotransformation; Cricetinae; Diethylnitrosamine; DNA; DNA Adducts; Guanine; Injections, Intraperitoneal; Male; Mesocricetus; Spermatogonia

1995
Diethylnitrosamine exposure-responses for DNA damage, centrilobular cytotoxicity, cell proliferation and carcinogenesis in rat liver exhibit some non-linearities.
    Carcinogenesis, 1996, Volume: 17, Issue:10

    Topics: Alkylating Agents; Alkylation; Animals; Cell Division; Diethylnitrosamine; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Guanine; Liver Neoplasms; Male; Rats; Rats, Inbred F344

1996
Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine.
    Cancer research, 1997, Apr-01, Volume: 57, Issue:7

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Colchicine; Diethylnitrosamine; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Guanine; Kidney; Linear Models; Liver Neoplasms; Lung; Male; Myocardium; Pancreas; Rats; Rats, Inbred F344; Risk Assessment; Time Factors

1997
Inhibition by green tea extract of diethylnitrosamine-initiated but not choline-deficient, L-amino acid-defined diet-associated development of putative preneoplastic, glutathione S-transferase placental form-positive lesions in rat liver.
    Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:4

    Topics: Alanine Transaminase; Animals; Choline Deficiency; Diet; Diethylnitrosamine; DNA; Glutathione Transferase; Guanine; Liver Neoplasms; Male; Plant Extracts; Precancerous Conditions; Rats; Rats, Inbred F344; Tea

1997
Mutation and formation of methyl- and hydroxylguanine adducts in DNA caused by N-nitrosodimethylamine and N-nitrosodiethylamine with UVA irradiation.
    Carcinogenesis, 1997, Volume: 18, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Bacterial Proteins; Deoxyguanosine; Diethylnitrosamine; Dimethylnitrosamine; DNA; DNA Adducts; DNA Repair; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Guanine; Methyltransferases; Mutagenesis; Mutagenicity Tests; Oxidation-Reduction; Plasmids; Salmonella typhimurium; Ultraviolet Rays

1997
DNA adducts, mutant frequencies, and mutation spectra in various organs of lambda lacZ mice exposed to ethylating agents.
    Environmental and molecular mutagenesis, 1998, Volume: 31, Issue:1

    Topics: Animals; Bone Marrow; Brain; Diethylnitrosamine; DNA Adducts; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Guanine; Lac Operon; Liver; Mice; Mice, Transgenic; Mutagens

1998
Formation and persistence of the miscoding DNA alkylation product O6-ethylguanine in male germ cells of the hamster.
    Mutation research, 1997, Volume: 385, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Carcinogens; Cricetinae; Diethylnitrosamine; DNA; DNA Adducts; DNA Damage; DNA Repair; Ethylnitrosourea; Fluorescent Antibody Technique, Indirect; Guanine; Male; Mesocricetus; Spermatogonia

1997
In vitro DNA deamination by alpha-nitrosaminoaldehydes determined by GC/MS-SIM quantitation.
    Chemical research in toxicology, 2000, Volume: 13, Issue:2

    Topics: Adenine; Aldehydes; Animals; Cattle; Cytosine; Deamination; Diethylnitrosamine; DNA; Gas Chromatography-Mass Spectrometry; Guanine; Nitrosamines

2000
Alpha-benzene hexachloride exerts hormesis in preneoplastic lesion formation of rat hepatocarcinogenesis with the possible role for hepatic detoxifying enzymes.
    Cancer letters, 2006, Aug-18, Volume: 240, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Aryl Hydrocarbon Hydroxylases; Cell Proliferation; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Diethylnitrosamine; DNA Damage; Dose-Response Relationship, Drug; Glutathione S-Transferase pi; Guanine; Hexachlorocyclohexane; Insecticides; Liver; Liver Neoplasms, Experimental; Male; Membrane Proteins; NADPH-Ferrihemoprotein Reductase; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; RNA, Messenger; Testosterone

2006
Augmentation of diethylnitrosamine-induced early stages of rat hepatocarcinogenesis by 1,2-dimethylhydrazine.
    Drug and chemical toxicology, 2019, Volume: 42, Issue:6

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Colon; Diethylnitrosamine; DNA Adducts; Drug Synergism; Guanine; Liver Neoplasms, Experimental; Male; Mutation; Rats; Rats, Wistar

2019