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diethylnitrosamine and deoxyguanosine

diethylnitrosamine has been researched along with deoxyguanosine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.89)18.7374
1990's8 (21.05)18.2507
2000's17 (44.74)29.6817
2010's10 (26.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Floyd, RA; Hinrichsen, LI; Sudilovsky, O1
Den Engelse, L; Hermsen, T; Kriek, E; Menkveld, GJ; Scherer, E; Van der Laken, CJ1
Chung, FL; Hecht, SS1
Bedell, MA; Dyroff, MC; Huh, N; Kirstein, U; Popp, JA; Rajewsky, MF; Swenberg, JA1
Appel, KE; Dahlhaus, M1
Asamoto, M; Iwase, T; Kato, T; Matsumoto, K; Montesano, R; Nagao, S; Ozaki, K; Tsuda, H; Wild, CP1
Bell, D; Groopman, JD; Lucier, GW; Miller, BD; Seacat, AM; Sutter, TR; Tritscher, AM; Yager, JD1
Arimoto-Kobayashi, S; Hayatsu, H; Kaji, K; Sweetman, GM1
Cho, M; Hiasa, Y; Kitahori, Y; Konishi, N; Nakagawa, Y; Sato, M1
Ando, J; Kudoh, K; Maekawa, A; Miyajima, K; Nakae, D; Shiraki, K; Takahashi, M; Yoshida, M1
Cui, W; Goelzer, P; Loeppky, RN; Park, M; Ye, Q1
Kim, AH; Lucier, GW; Walker, NJ; Wong, VA; Wyde, ME1
Chen, Y; Goelzer, P; Loeppky, RN; Ye, Q1
Fukushima, S; Funae, Y; Imaoka, S; Kinoshita, A; Morimura, K; Shen, J; Wanibuchi, H; Wei, M1
Christensen, MJ; Moak, MA; Wycherly, BJ1
Kaneko, S; Kurata, T; Matsuda, M; Nakamoto, Y; Suzuki, S1
Dennehy, MK; Loeppky, RN1
Fukushima, S; Kinoshita, A; Kushida, M; Morimura, K; Okuno, Y; Ozaki, K; Sukata, T; Uwagawa, S; Wanibuchi, H1
Fukushima, S; Hagihara, A; Iwai, S; Makino, S; Min, W; Mori, S; Morimura, K; Murai, T; Seki, S1
Chakraborty, T; Chatterjee, A; Chatterjee, M; Saralaya, MG1
Chakraborty, T; Chatterjee, A; Chatterjee, M; Ghosh, B; Pandey, N; Rana, B1
Chakraborty, T; Chatterjee, A; Chatterjee, M; Dhachinamoorthi, D; Kumar P, A; Rana, A1
Hashimoto, K; Sato, I; Takasaki, W; Tsuda, S1
Dewa, Y; Jin, M; Mitsumori, K; Muguruma, M; Nishimura, J; Okamura, T; Saegusa, Y; Tasaki, M; Umemura, T1
Dewa, Y; Jin, M; Mitsumori, K; Muguruma, M; Nishimura, J; Okamura, T; Saegusa, Y; Umemura, T1
Doi, K; Inoue, M; Kitano, M; Uematsu, N; Wanibuchi, H; Wei, M1
de la Monte, SM; Tong, M1
Doi, K; Fukushima, S; Hamoud, AS; Kakehashi, A; Kitano, M; Kushida, M; Morimura, K; Wanibuchi, H; Wei, M; Yamaguchi, T1
Dewa, Y; Hayashi, H; Imaoka, M; Ishii, Y; Kemmochi, S; Kuwata, K; Mitsumori, K; Morita, R; Shibutani, M; Shimamoto, K; Suzuki, K; Taniai, E1
Hayashi, H; Imaoka, M; Ishii, Y; Mitsumori, K; Morita, R; Shibutani, M; Shimamoto, K; Suzuki, K; Taniai, E1
Maeda, M; Sakaida, I; Takami, T; Terai, S1
Xie, KQ; Yu, LH; Zeng, T; Zhang, CL; Zhao, XL; Zhu, ZP1
Hojo, Y; Ishii, Y; Mitsumori, K; Shibutani, M; Shimamoto, K; Shiraki, A; Suzuki, K; Tsuchiya, T1
Hayashi, H; Ishii, Y; Mitsumori, K; Morita, R; Shibutani, M; Shimamoto, K; Suzuki, K; Taniai, E1
Fujii, Y; Hayashi, SM; Ishii, Y; Kimura, M; Morita, R; Shibutani, M; Suzuki, K; Yamamoto, R1
Fujii, Y; Ishii, Y; Kimura, M; Mitsumori, K; Morita, R; Segawa, R; Shibutani, M; Wang, L; Yamamoto, R1
Arima, S; Fujita, H; Ibusuki, R; Ido, A; Kumagai, K; Kumamoto, R; Mawatari, S; Moriuchi, A; Numata, M; Oda, K; Oketani, M; Tamai, T; Tanoue, S; Tsubouchi, H; Uto, H1
Akazawa, Y; Fujii, H; Furuya, S; Hara, M; Hirayama, K; Kono, H; Nakata, Y; Sun, C1

Other Studies

38 other study(ies) available for diethylnitrosamine and deoxyguanosine

ArticleYear
Is 8-hydroxydeoxyguanosine a mediator of carcinogenesis by a choline-devoid diet in the rat liver?
    Carcinogenesis, 1990, Volume: 11, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Choline Deficiency; Deoxyguanosine; Diethylnitrosamine; DNA; DNA Damage; DNA, Neoplasm; Hepatectomy; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344

1990
Immunohistochemical localization of O6-ethyldeoxyguanosine and deoxyguanosin-8-yl-(acetyl)aminofluorene in liver sections of rats treated with diethylnitrosamine, ethylnitrosourea or N-acetylaminofluorene.
    Carcinogenesis, 1985, Volume: 6, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Deoxyguanosine; Diethylnitrosamine; DNA; Ethylnitrosourea; Female; Histocytochemistry; Immunoenzyme Techniques; Liver; Nitrosamines; Nitrosourea Compounds; Rats; Rats, Inbred Strains

1985
Formation of the cyclic 1,N2-glyoxal-deoxyguanosine adduct upon reaction of N-nitroso-2-hydroxymorpholine with deoxyguanosine.
    Carcinogenesis, 1985, Volume: 6, Issue:11

    Topics: Chemical Phenomena; Chemistry; Deoxyguanosine; Diethylnitrosamine; Nitrosamines

1985
O4-ethyldeoxythymidine, but not O6-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamine.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:6

    Topics: Alkylation; Deoxyguanosine; Diethylnitrosamine; DNA; DNA Repair; Liver; Nitrosamines; Radioimmunoassay; Thymidine

1984
N-nitrosodimethylamine, N-nitrosodiethylamine, and N-nitrosomorpholine fail to generate 8-hydroxy-2'-deoxyguanosine in liver DNA of male F344 rats.
    Mutation research, 1993, Volume: 285, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; Diethylnitrosamine; Dimethylnitrosamine; DNA; DNA Damage; Liver; Male; Nitrosamines; Oxidation-Reduction; Rats; Rats, Inbred F344

1993
Decreased dimethylnitrosamine-induced O6- and N7-methyldeoxyguanosine levels correlate with development and progression of lesions in rat hepatocarcinogenesis.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:12

    Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Deoxyguanosine; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Glutathione Transferase; Immunohistochemistry; Liver Neoplasms; Male; Neoplasm Transplantation; Rats; Rats, Inbred F344

1993
Increased oxidative DNA damage in livers of 2,3,7,8-tetrachlorodibenzo-p-dioxin treated intact but not ovariectomized rats.
    Cancer letters, 1996, Jan-02, Volume: 98, Issue:2

    Topics: Animals; Carcinogens; Cocarcinogenesis; Deoxyguanosine; Diethylnitrosamine; DNA; DNA Damage; Estradiol; Female; Liver; Liver Neoplasms, Experimental; Ovariectomy; Ovary; Oxidation-Reduction; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley

1996
Mutation and formation of methyl- and hydroxylguanine adducts in DNA caused by N-nitrosodimethylamine and N-nitrosodiethylamine with UVA irradiation.
    Carcinogenesis, 1997, Volume: 18, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Bacterial Proteins; Deoxyguanosine; Diethylnitrosamine; Dimethylnitrosamine; DNA; DNA Adducts; DNA Repair; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Guanine; Methyltransferases; Mutagenesis; Mutagenicity Tests; Oxidation-Reduction; Plasmids; Salmonella typhimurium; Ultraviolet Rays

1997
Formation of 8-hydroxydeoxyguanosine in rat kidney DNA after administration of N-ethyl-N-hydroxyethylnitrosamine.
    Cancer letters, 1998, Feb-13, Volume: 124, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Deoxyguanosine; Diethylnitrosamine; DNA; DNA Damage; Dose-Response Relationship, Drug; Glutathione; Kidney; Kinetics; Liver; Lung; Male; Maleates; Oxidation-Reduction; Rats; Rats, Wistar

1998
Hepatotoxicity and consequently increased cell proliferation are associated with flumequine hepatocarcinogenesis in mice.
    Cancer letters, 1999, Jul-01, Volume: 141, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenoma; Animals; Anti-Infective Agents; Carcinogenicity Tests; Cell Division; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Deoxyguanosine; Diethylnitrosamine; Fluoroquinolones; Immunohistochemistry; Liver; Liver Neoplasms; Male; Mice; Phenobarbital; Proliferating Cell Nuclear Antigen; Quinolizines; Steroid Hydroxylases

1999
Glyoxal-guanine DNA adducts: detection, stability and formation in vivo from nitrosamines.
    IARC scientific publications, 1999, Issue:150

    Topics: Animals; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; Diethylnitrosamine; DNA Adducts; Isomerism; Kinetics; Liver; Magnetic Resonance Spectroscopy; Male; Models, Chemical; Models, Molecular; Nitrosamines; Rats; Rats, Wistar

1999
Induction of hepatic 8-oxo-deoxyguanosine adducts by 2,3,7,8-tetrachlorodibenzo-p-dioxin in Sprague-Dawley rats is female-specific and estrogen-dependent.
    Chemical research in toxicology, 2001, Volume: 14, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Cocarcinogenesis; Deoxyguanosine; Diethylnitrosamine; DNA; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Estradiol; Female; Liver; Liver Neoplasms, Experimental; Male; Ovariectomy; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Sex Characteristics

2001
DNA adducts from N-nitrosodiethanolamine and related beta-oxidized nitrosamines in vivo: (32)P-postlabeling methods for glyoxal- and O(6)-hydroxyethyldeoxyguanosine adducts.
    Chemical research in toxicology, 2002, Volume: 15, Issue:4

    Topics: Animals; Autoradiography; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Deoxyguanosine; Diethylnitrosamine; DNA Adducts; Dose-Response Relationship, Drug; Glyoxal; Nitrosamines; Oxidation-Reduction; Phosphorus Radioisotopes; Rats

2002
Phenobarbital at low dose exerts hormesis in rat hepatocarcinogenesis by reducing oxidative DNA damage, altering cell proliferation, apoptosis and gene expression.
    Carcinogenesis, 2003, Volume: 24, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Alkylating Agents; Animals; Apoptosis; Cell Division; Cytochrome P-450 Enzyme System; Deoxyguanosine; Diethylnitrosamine; DNA Damage; DNA-Formamidopyrimidine Glycosylase; DNA, Neoplasm; Electron Spin Resonance Spectroscopy; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Neoplastic; Glutamate Decarboxylase; Glutathione Transferase; Liver Neoplasms, Experimental; Male; N-Glycosyl Hydrolases; Oxidative Stress; Phenobarbital; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2003
High dietary intake of sodium selenite induces oxidative DNA damage in rat liver.
    Nutrition and cancer, 2004, Volume: 48, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Animals; Carcinogens; Deoxyguanosine; Dietary Supplements; Diethylnitrosamine; DNA; DNA Damage; DNA Glycosylases; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione Peroxidase; Liver; Male; Neoplasms, Experimental; Oxidation-Reduction; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium Selenite

2004
Interferon-gamma-mediated hepatocarcinogenesis in mice treated with diethylnitrosamine.
    Laboratory investigation; a journal of technical methods and pathology, 2005, Volume: 85, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Hepatocellular; Cytochrome P-450 CYP2E1; Deoxyguanosine; Diethylnitrosamine; DNA Damage; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Interferon-gamma; Liver; Liver Neoplasms, Experimental; Male; Membrane Proteins; Mice; Mice, Knockout; Receptor, Interferon alpha-beta; Receptors, Interferon; RNA, Messenger; RNA, Neoplasm; Water Supply

2005
Mass spectrometric methodology for the determination of glyoxaldeoxyguanosine and O6-hydroxyethyldeoxyguanosine DNA adducts produced by nitrosamine bident carcinogens.
    Chemical research in toxicology, 2005, Volume: 18, Issue:3

    Topics: Animals; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Deoxyguanosine; Diethylnitrosamine; DNA Adducts; Dose-Response Relationship, Drug; Glyoxal; Rats; Spectrometry, Mass, Electrospray Ionization

2005
Low dose DDT inhibition of hepatocarcinogenesis initiated by diethylnitrosamine in male rats: possible mechanisms.
    Toxicology and applied pharmacology, 2005, Nov-01, Volume: 208, Issue:3

    Topics: Administration, Oral; Animals; Apoptosis; Cell Proliferation; Connexins; Cytochrome P-450 Enzyme System; DDT; Deoxyguanosine; Diethylnitrosamine; Disease Models, Animal; DNA Damage; DNA Glycosylases; DNA, Single-Stranded; Dose-Response Relationship, Drug; Drug Administration Schedule; Gap Junction beta-1 Protein; Gene Expression; Glutathione S-Transferase pi; Glutathione Transferase; Hepatocyte Nuclear Factor 1-alpha; Immunochemistry; Injections, Intraperitoneal; Liver Neoplasms, Experimental; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; RNA, Messenger; Time Factors; Up-Regulation

2005
High sensitivity of fatty liver Shionogi (FLS) mice to diethylnitrosamine hepatocarcinogenesis: comparison to C3H and C57 mice.
    Cancer letters, 2007, Feb-08, Volume: 246, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Alkylating Agents; Animals; Deoxyguanosine; Diethylnitrosamine; Disease Progression; DNA; Fatty Liver; Humans; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred Strains; Proliferating Cell Nuclear Antigen; Species Specificity

2007
Chemopreventive effect of vanadium in a rodent model of chemical hepatocarcinogenesis: reflections in oxidative DNA damage, energy-dispersive X-ray fluorescence profile and metallothionein expression.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2006, Volume: 11, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cell Transformation, Neoplastic; Chemoprevention; Deoxyguanosine; Diethylnitrosamine; Disease Models, Animal; DNA Damage; Elements; Liver; Liver Neoplasms, Experimental; Male; Metallothionein; Phenobarbital; Rats; Rats, Sprague-Dawley; Spectrometry, X-Ray Emission; Vanadium

2006
Molecular basis of anticlastogenic potential of vanadium in vivo during the early stages of diethylnitrosamine-induced hepatocarcinogenesis in rats.
    Mutation research, 2006, Oct-30, Volume: 609, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antimutagenic Agents; Chromosome Aberrations; Deoxyguanosine; Diethylnitrosamine; DNA Damage; Liver Neoplasms, Experimental; Male; Rats; Rats, Sprague-Dawley; Time Factors; Vanadates; Vanadium

2006
Carcinogen-induced early molecular events and its implication in the initiation of chemical hepatocarcinogenesis in rats: chemopreventive role of vanadium on this process.
    Biochimica et biophysica acta, 2007, Volume: 1772, Issue:1

    Topics: Alkylating Agents; Animals; Carcinogens; Cell Transformation, Neoplastic; Chemoprevention; Deoxyguanosine; Diethylnitrosamine; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Liver Neoplasms, Experimental; Male; Rats; Rats, Sprague-Dawley; Vanadates

2007
DNA damage measured by comet assay and 8-OH-dG formation related to blood chemical analyses in aged rats.
    The Journal of toxicological sciences, 2007, Volume: 32, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Blood Chemical Analysis; Comet Assay; Deoxyguanosine; Diethylnitrosamine; DNA Adducts; DNA Damage; DNA Repair; Hydrogen-Ion Concentration; Kidney; Liver; Male; Methyl Methanesulfonate; Mutagens; Rats; Rats, Inbred F344; Reactive Oxygen Species; Time Factors

2007
beta-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats.
    Toxicology, 2008, Feb-28, Volume: 244, Issue:2-3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; beta-Naphthoflavone; Blotting, Western; Cell Proliferation; Deoxyguanosine; Diethylnitrosamine; Enzyme Inhibitors; Glutathione Transferase; Hepatectomy; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Precancerous Conditions; Rats; Rats, Inbred F344; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; Thiobarbituric Acid Reactive Substances

2008
Possible involvement of oxidative stress in fenofibrate-induced hepatocarcinogenesis in rats.
    Archives of toxicology, 2008, Volume: 82, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Alkylating Agents; Animals; Body Weight; Carcinogens; Deoxyguanosine; Diethylnitrosamine; DNA; Eating; Fenofibrate; Gene Expression Regulation; Hepatectomy; Hypolipidemic Agents; Ki-67 Antigen; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Oxidative Stress; PPAR alpha; Precancerous Conditions; Rats; Rats, Inbred F344; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm

2008
Enhancement of preneoplastic lesion yield by Chios Mastic Gum in a rat liver medium-term carcinogenesis bioassay.
    Toxicology and applied pharmacology, 2009, Jan-01, Volume: 234, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogenicity Tests; Deoxyguanosine; Diethylnitrosamine; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutathione S-Transferase pi; Immunohistochemistry; Liver; Male; Mastic Resin; Mediterranean Region; Organ Size; Pistacia; Polymerase Chain Reaction; Precancerous Conditions; Rats; Rats, Inbred F344; Resins, Plant

2009
Mechanisms of nitrosamine-mediated neurodegeneration: potential relevance to sporadic Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2009, Volume: 17, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosine Triphosphate; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Cells, Cultured; Cerebellar Cortex; Choline O-Acetyltransferase; Deoxyguanosine; Diethylnitrosamine; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme-Linked Immunosorbent Assay; Insulin; Insulin-Like Growth Factor I; Mitochondria; Nerve Degeneration; Neurons; Oxidative Stress; Rats; Rats, Long-Evans; Receptor, IGF Type 2; Streptozocin; Ubiquitin

2009
Potassium bromate enhances N-ethyl-N-hydroxyethylnitrosamine-induced kidney carcinogenesis only at high doses in Wistar rats: indication of the existence of an enhancement threshold.
    Toxicologic pathology, 2009, Volume: 37, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Body Weight; Bromates; Carcinogens; Deoxyguanosine; Diethylnitrosamine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Gene Expression; Kidney; Kidney Neoplasms; Male; Organ Size; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger

2009
Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine.
    Toxicology, 2011, May-10, Volume: 283, Issue:2-3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Body Weight; Carcinogens; Deoxyguanosine; Diethylnitrosamine; DNA Damage; DNA, Complementary; Enzyme Induction; Free Radical Scavengers; Hepatectomy; Immunohistochemistry; Indoles; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Microarray Analysis; Microsomes, Liver; Organ Size; Oxidative Stress; Precancerous Conditions; Rats; Rats, Inbred F344; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Thiobarbituric Acid Reactive Substances

2011
Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats.
    The Journal of toxicological sciences, 2011, Volume: 36, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Alkylating Agents; Animals; Antioxidants; Carcinogens; Deoxyguanosine; Diethylnitrosamine; DNA Damage; Gene Expression Profiling; Hepatectomy; Indoles; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Oligonucleotide Array Sequence Analysis; Organ Size; Oxidative Stress; Rats; Rats, Inbred F344; Reactive Oxygen Species; Weight Gain

2011
Autologous bone marrow cell infusions suppress tumor initiation in hepatocarcinogenic mice with liver cirrhosis.
    Journal of gastroenterology and hepatology, 2012, Volume: 27 Suppl 2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Bone Marrow Transplantation; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Deoxyguanosine; Diethylnitrosamine; Green Fluorescent Proteins; Homeostasis; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Superoxide Dismutase; Time Factors; Transplantation, Autologous

2012
Protective effects of garlic oil on hepatocarcinoma induced by N-nitrosodiethylamine in rats.
    International journal of biological sciences, 2012, Volume: 8, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Allyl Compounds; Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis Regulatory Proteins; Biomarkers; Body Weight; Corn Oil; Deoxyguanosine; Diethylnitrosamine; DNA Damage; Drug Screening Assays, Antitumor; Gene Expression Profiling; Lipid Peroxidation; Liver; Liver Function Tests; Liver Neoplasms, Experimental; Male; Organ Size; Oxidative Stress; Oxidoreductases; Random Allocation; Rats; Rats, Wistar; Sulfides

2012
Liver tumor promoting effect of etofenprox in rats and its possible mechanism of action.
    The Journal of toxicological sciences, 2012, Volume: 37, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Constitutive Androstane Receptor; Deoxyguanosine; Diethylnitrosamine; Gene Expression; Glutathione Transferase; Insecticides; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Pyrethrins; Rats; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiobarbituric Acid Reactive Substances

2012
Liver tumor promoting effect of omeprazole in rats and its possible mechanism of action.
    The Journal of toxicological sciences, 2012, Volume: 37, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Aldehyde Dehydrogenase 1 Family; Animals; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochromes; Deoxyguanosine; Diethylnitrosamine; Glucuronosyltransferase; Glutathione Peroxidase; Glutathione Transferase; Hepatectomy; Injections, Intraperitoneal; Liver; Liver Neoplasms, Experimental; Male; NAD(P)H Dehydrogenase (Quinone); Omeprazole; Oxidative Stress; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; Retinal Dehydrogenase; Up-Regulation

2012
Effect of enzymatically modified isoquercitrin on preneoplastic liver cell lesions induced by thioacetamide promotion in a two-stage hepatocarcinogenesis model using rats.
    Toxicology, 2013, Mar-08, Volume: 305

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Carcinogens; Cell Line, Tumor; Deoxyguanosine; Diethylnitrosamine; Glutathione; Immunohistochemistry; In Situ Nick-End Labeling; Liver Neoplasms, Experimental; Lymphocytes; Macrophages; Male; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Quercetin; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; Receptors, TNF-Related Apoptosis-Inducing Ligand; Thioacetamide; Thiobarbituric Acid Reactive Substances

2013
Inhibitory effect of α-lipoic acid on thioacetamide-induced tumor promotion through suppression of inflammatory cell responses in a two-stage hepatocarcinogenesis model in rats.
    Chemico-biological interactions, 2013, Sep-25, Volume: 205, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Apoptosis; Carcinogens; Cocarcinogenesis; Deoxyguanosine; Diethylnitrosamine; Glutathione S-Transferase pi; Inflammation Mediators; Liver; Liver Neoplasms, Experimental; Macrophages; Male; Rats; Rats, Inbred F344; Thioacetamide; Thiobarbituric Acid Reactive Substances; Thioctic Acid

2013
Dietary fructose enhances the incidence of precancerous hepatocytes induced by administration of diethylnitrosamine in rat.
    European journal of medical research, 2013, Dec-09, Volume: 18

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Animals; Biomarkers; Body Weight; Deoxyguanosine; Diet, High-Fat; Dietary Carbohydrates; Diethylnitrosamine; Fatty Liver; Fructose; Gene Expression Regulation; Glutathione Transferase; Hepatocytes; Incidence; Male; Organ Size; Oxidative Stress; Precancerous Conditions; Rats; Rats, Sprague-Dawley; RNA, Messenger

2013
Interleukin-17A Plays a Pivotal Role in Chemically Induced Hepatocellular Carcinoma in Mice.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinoma, Hepatocellular; Cell Proliferation; Deoxyguanosine; Diethylnitrosamine; DNA Damage; Gene Expression Regulation, Neoplastic; Interleukin-17; Interleukin-6; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Tumor Necrosis Factor-alpha

2016