diethylnitrosamine has been researched along with cyclin d1 in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 20 (90.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gupta, S; Rao, KV; Sundarrajan, M | 1 |
| Parekh, P; Rao, KV | 1 |
| Knudsen, ES; Mayhew, CN; McClendon, AK; Reed, CA | 1 |
| Alhamdani, A; Alwahaibi, NY; Budin, SB; Mohamed, J | 1 |
| Chen, C; Hu, Q; Li, Q; Li, Z; Luo, X; San, J; Wang, D; Wang, G; Yang, Z; Zhang, Z; Zheng, J | 1 |
| Aller, MA; Ko, KS; Li, TW; Peng, J; Tang, X; Xia, M; Yang, H | 1 |
| Devaraj, SN; Halagowder, D; Khan, MS | 1 |
| Blaner, WS; Gottesman, ME; Shirakami, Y | 1 |
| Lee, J; Lim, KT | 2 |
| Choi, H; Kim, DJ; Kim, H; Kim, TM; Lee, HJ; Moon, HS | 1 |
| Agrawal, SS; Alhaider, AA; Saraswati, S | 1 |
| Ausman, LM; Hu, KQ; Ip, BC; Liu, C; Obin, MS; Smith, DE; Wang, XD | 1 |
| Huang, CZ; Huang, WZ; Tang, DL; Zhang, G | 1 |
| Devaraj, H; MadanKumar, P; Manikandan, S; NaveenKumar, P; NiranjaliDevaraj, S | 1 |
| Eguchi, A; Feldstein, AE; Font-Burgada, J; Johnson, CD; Karin, M; Povero, D; Wree, A | 1 |
| Buckley, K; Guo, GL; Kong, B; Li, G; Luyendyk, JP; Tawfik, O; Williams, JA; Zhu, Y | 1 |
| Gao, L; Han, Z; Jiang, J; Li, R; Li, X; Liang, L; Shi, R; Wei, L; Wu, Y; Yang, X; Ye, F; Yu, Y; Zhao, Q | 1 |
| Dong, J; Ke, MY; Liu, C; Lv, Y; Ma, F; Monga, SPS; Ren, YF; Wu, R; Zhang, XF | 1 |
| Abdelghany, RH; El-Ahwany, E; Goda, R; Helal, NS; Mahmoud, AAA; Saber, S | 1 |
| Abdelnasser, A; Abdo, WS; Basuony, M; Eldin, AS; Elsaeed, B; Khodir, AE; Mahmoud, M; Medhat, R; Megahed, N; Nader, K; Saber, S; Salama, MM; Shawky, A; Soliman, WE | 1 |
| Ghanim, AMH; Saber, S; Younis, NS | 1 |
22 other study(ies) available for diethylnitrosamine and cyclin d1
| Article | Year |
|---|---|
Overexpression of cyclin D1 is associated with the decondensation of chromatin during den-induced sequential hepatocarcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chromatin; Cyclin D1; Diethylnitrosamine; Gene Expression Regulation, Neoplastic; Genes, cdc; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Up-Regulation | 2002 |
Overexpression of cyclin D1 is associated with elevated levels of MAP kinases, Akt and Pak1 during diethylnitrosamine-induced progressive liver carcinogenesis.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Cyclin D1; Diethylnitrosamine; Disease Progression; Gene Expression Regulation; Liver Neoplasms; Male; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p21-Activated Kinases; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley | 2007 |
Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control.
Topics: Alkylating Agents; Animals; Carcinoma, Hepatocellular; Cell Cycle; Cyclin D1; Diethylnitrosamine; DNA Damage; DNA Replication; E2F1 Transcription Factor; Gene Deletion; Liver Neoplasms; Mice; Mice, Transgenic; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; Retinoblastoma-Like Protein p130 | 2010 |
Nuclear factor-kappa B as a promising target for selenium chemoprevention in rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Cyclin D1; Diethylnitrosamine; Gene Expression Regulation, Neoplastic; Liver; Liver Neoplasms, Experimental; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Selenite; Time Factors; Transforming Growth Factor alpha | 2010 |
Aberrant expression of the p53-inducible antiproliferative gene BTG2 in hepatocellular carcinoma is associated with overexpression of the cell cycle-related proteins.
Topics: Adult; Aged; Aged, 80 and over; Animals; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Line, Tumor; Cyclin D1; Cyclin E; Diethylnitrosamine; Disease Models, Animal; Female; Humans; Immediate-Early Proteins; Liver Neoplasms; Male; Middle Aged; Rats; Rats, Wistar; RNA, Messenger; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2011 |
A mouse model of cholestasis-associated cholangiocarcinoma and transcription factors involved in progression.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Basic Helix-Loop-Helix Transcription Factors; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Cholestasis; Cyclin D1; Diethylnitrosamine; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Neoplastic; Hyperplasia; Hypoxia-Inducible Factor 1, alpha Subunit; Ligation; Liver; Male; Mice; Mice, Inbred BALB C; MicroRNAs; Proto-Oncogene Proteins c-myc; Repressor Proteins; RNA Interference; RNA-Binding Proteins; Signal Transduction; Time Factors; Transcription Factors | 2011 |
Methylated chrysin induces co-ordinated attenuation of the canonical Wnt and NF-kB signaling pathway and upregulates apoptotic gene expression in the early hepatocarcinogenesis rat model.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Casein Kinase II; Caspase 3; Cyclin D1; Cyclooxygenase 2; Diethylnitrosamine; Disease Models, Animal; Flavones; Flavonoids; Gene Expression Regulation, Neoplastic; Liver Neoplasms; Male; NF-kappa B; Nitric Oxide Synthase Type II; Precancerous Conditions; Rats; Rats, Wistar; Signal Transduction; Tumor Suppressor Protein p53; Up-Regulation; Wnt Proteins | 2011 |
Diethylnitrosamine-induced hepatocarcinogenesis is suppressed in lecithin:retinol acyltransferase-deficient mice primarily through retinoid actions immediately after carcinogen administration.
Topics: Acyltransferases; Alanine Transaminase; Animals; Apoptosis; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cytochrome P-450 Enzyme System; Diethylnitrosamine; DNA Modification Methylases; DNA Repair Enzymes; Hepatic Stellate Cells; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; O(6)-Methylguanine-DNA Methyltransferase; Retinoids; Signal Transduction; Tretinoin; Tumor Suppressor Proteins | 2012 |
Normalizing effect of SJSZ glycoprotein (38 kDa) on proliferating cell nuclear antigen and interferon-γ in diethylnitrosamine-induced mice splenocytes.
Topics: Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; Diethylnitrosamine; Fruit; Glycoproteins; Interferon-gamma; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Molecular Weight; Phosphorylation; Plant Proteins; Primary Cell Culture; Proliferating Cell Nuclear Antigen; Reverse Transcriptase Polymerase Chain Reaction; Spleen; Styrax; Thymidine; Time Factors | 2013 |
Inductive effect of phytoglycoprotein (38 kDa) on G₀/G₁ arrest and apoptosis in diethylnitrosamine-treated ICR mice.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Caspase 3; Caspase 9; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cytochromes c; Diethylnitrosamine; G1 Phase Cell Cycle Checkpoints; Gene Expression; Glycoproteins; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred ICR; Plant Proteins; Proliferating Cell Nuclear Antigen; Styrax; Tumor Suppressor Protein p53 | 2013 |
Panax ginseng exerts antiproliferative effects on rat hepatocarcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Cell Proliferation; Cyclin D1; Cyclin G1; Diethylnitrosamine; Dose-Response Relationship, Drug; Down-Regulation; Glutathione Transferase; Hepatocytes; Insulin-Like Growth Factor I; Liver; Liver Neoplasms, Experimental; Male; Oligonucleotide Array Sequence Analysis; Organ Size; Panax; Plant Extracts; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Suppressor Protein p53 | 2013 |
Anticarcinogenic effect of brucine in diethylnitrosamine initiated and phenobarbital-promoted hepatocarcinogenesis in rats.
Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cyclin D1; Diethylnitrosamine; Female; Gene Expression Regulation; Immunohistochemistry; Lipid Peroxidation; Liver Neoplasms, Experimental; Phenobarbital; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Strychnine; Vascular Endothelial Growth Factor A | 2013 |
Lycopene metabolite, apo-10'-lycopenoic acid, inhibits diethylnitrosamine-initiated, high fat diet-promoted hepatic inflammation and tumorigenesis in mice.
Topics: Alkylating Agents; Animals; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Carotenoids; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Diet, High-Fat; Diethylnitrosamine; Fatty Acids, Unsaturated; Female; Glucose Tolerance Test; Humans; Inflammation; Liver Neoplasms; Lycopene; Mice; Mice, Inbred C57BL; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2013 |
In vivo study on the effects of curcumin on the expression profiles of anti-tumour genes (VEGF, CyclinD1 and CDK4) in liver of rats injected with DEN.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Curcumin; Cyclin D1; Cyclin-Dependent Kinase 4; Diethylnitrosamine; gamma-Glutamyltransferase; Gene Expression Profiling; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Injections; Liver; Malondialdehyde; Nitric Oxide; Rats; Rats, Wistar; Superoxide Dismutase; Vascular Endothelial Growth Factor A | 2013 |
Morin ameliorates chemically induced liver fibrosis in vivo and inhibits stellate cell proliferation in vitro by suppressing Wnt/β-catenin signaling.
Topics: Animals; beta Catenin; Cell Line; Cell Proliferation; Cell Survival; Cyclin D1; Cytoprotection; Diethylnitrosamine; Dose-Response Relationship, Drug; Flavonoids; G1 Phase Cell Cycle Checkpoints; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hepatic Stellate Cells; Humans; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Oxidative Stress; Rats; Rats, Wistar; Time Factors; Wnt Signaling Pathway | 2014 |
Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation.
Topics: Animals; BH3 Interacting Domain Death Agonist Protein; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cyclin D1; Diethylnitrosamine; Disease Models, Animal; Hepatocytes; Hydrogen Peroxide; Inflammation; Interleukin-6; Liver; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Non-alcoholic Fatty Liver Disease; Pyridines; Tumor Necrosis Factor-alpha | 2015 |
Mice with hepatocyte-specific FXR deficiency are resistant to spontaneous but susceptible to cholic acid-induced hepatocarcinogenesis.
Topics: Animals; Apoptosis; Carcinogenesis; Cell Proliferation; Cholic Acid; Cyclin D1; Diethylnitrosamine; Hepatocytes; Janus Kinases; Liver Neoplasms; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase Kinases; Models, Animal; Receptors, Cytoplasmic and Nuclear; Signal Transduction; STAT3 Transcription Factor; Tumor Suppressor Protein p53 | 2016 |
Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway.
Topics: Animals; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cyclin D1; Cytokines; Cytoprotection; Diethylnitrosamine; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Hepatic Stellate Cells; Lipopolysaccharides; Liver; Liver Cirrhosis, Experimental; Male; NF-kappa B; Protective Agents; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4 | 2016 |
Activation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cyclin D1; Diethylnitrosamine; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Health Status Disparities; Humans; Liver Neoplasms; Male; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Receptor, Platelet-Derived Growth Factor alpha; Sex Factors; Sex-Determining Region Y Protein; Signal Transduction; SOX9 Transcription Factor; Time Factors; Tumor Microenvironment; Up-Regulation | 2017 |
Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cyclin D1; Diethylnitrosamine; Fosinopril; Liver Neoplasms, Experimental; Losartan; Male; Matrix Metalloproteinase 2; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Niacinamide; Perindopril; Phenylurea Compounds; Phosphorylation; Renin-Angiotensin System; Signal Transduction; Sorafenib; Time Factors; Transcription Factor RelA; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2018 |
Telmisartan attenuates N-nitrosodiethylamine-induced hepatocellular carcinoma in mice by modulating the NF-κB-TAK1-ERK1/2 axis in the context of PPARγ agonistic activity.
Topics: Animals; Antihypertensive Agents; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; Cyclin D1; Diethylnitrosamine; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; MAP Kinase Kinase Kinases; Matrix Metalloproteinase 2; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; PPAR gamma; Telmisartan; Transcription Factor RelA; Vascular Endothelial Growth Factor A | 2019 |
Mebendazole augments sensitivity to sorafenib by targeting MAPK and BCL-2 signalling in n-nitrosodiethylamine-induced murine hepatocellular carcinoma.
Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cyclin D1; Diethylnitrosamine; Hep G2 Cells; Humans; Kaplan-Meier Estimate; Ki-67 Antigen; Liver Neoplasms; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Mebendazole; Mice; Mitogen-Activated Protein Kinases; Molecular Targeted Therapy; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Signal Transduction; Sorafenib; Tissue Inhibitor of Metalloproteinase-1; Tumor Burden; Vascular Endothelial Growth Factor A | 2019 |