diethylhexyl phthalate has been researched along with clofibrate in 83 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (37.35) | 18.7374 |
| 1990's | 46 (55.42) | 18.2507 |
| 2000's | 4 (4.82) | 29.6817 |
| 2010's | 2 (2.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aoki, T; Hakoi, K; Ito, N; Kato, T; Ozaki, K; Sato, K; Tsuda, H; Uwagawa, S; Yamaguchi, S | 1 |
| Baldwin, LA; Calabrese, EJ; Leonard, DA; Ochs, JB | 1 |
| Calder, IC; Nicholls-Grzemski, FA; Priestly, BG | 1 |
| Imanaka, T; Itoga, H; Okawa, S; Suga, T; Watanabe, T | 1 |
| Gibson, GG; Lake, BG | 1 |
| Iida, T; Suga, T; Tamura, H; Watanabe, T | 2 |
| Mikalsen, SO; Rivedal, E; Sanner, T | 1 |
| Gemmell, MA; Giometti, CS; Lalwani, ND; Reddy, JK; Taylor, J; Tollaksen, SL | 1 |
| Asakawa, E; Fukushima, S; Hagiwara, A; Ogiso, T; Tamano, S | 1 |
| Kaalhus, O; Mikalsen, SO; Reith, A; Sanner, T | 1 |
| Crane, DI; Masters, CJ; Zamattia, J | 1 |
| Mikalsen, SO; Ruyter, B; Sanner, T | 1 |
| Appelkvist, EL; Dallner, G; Kalén, A | 1 |
| Holen, I; Mikalsen, SO; Sanner, T | 1 |
| Hasegawa, R; Kurokawa, Y; Sai, K; Takagi, A; Umemura, T | 1 |
| Bartles, JR; Fayos, BE; Isoye, ST; Khuon, S; Lin, XH; Nehme, CL; Rao, MS; Reddy, JK; Zhang, LQ | 1 |
| Hirose, A; Mizugaki, M; Yokota, S | 1 |
| Horie, S; Ogawa, S; Suga, T | 1 |
| Horie, S; Suga, T; Suzuki, T | 1 |
| Brady, LJ; Brady, PS; Marine, KA; Ramsay, RR | 1 |
| Garvey, LK; Hamm, TE; Popp, JA; Swenberg, JA | 1 |
| Balzer, I; Huth, W | 1 |
| Brady, LJ; Brady, PS | 1 |
| Chen, N; Crane, DI; Masters, C | 1 |
| Hayashi, Y; Imazawa, T; Kurokawa, Y; Matushima, Y; Takamura, N | 1 |
| Gill, SS; Kaur, S | 1 |
| Chescoe, D; Grasso, P; Hinton, RH; Price, SC; Wright, M | 1 |
| Gibson, GG; Lake, BG; Sharma, R | 1 |
| Carrino, JJ; Goel, SK; Hashimoto, T; Laffler, TG; Lalwani, ND; Nemali, MR; Osumi, T; Reddy, JK; Reddy, MK; Sperbeck, SJ | 1 |
| Evarts, RE; Lalwani, ND; Rao, MS; Reddy, JK; Reddy, MK; Singh, B; Thorgeirsson, S; Usman, MI | 1 |
| Evans, JG; Gangolli, SD; Gray, TJ; Kozlen, SL; Lake, BG; Young, PJ | 1 |
| Ichihara, K; Kaku, M; Kusunose, E; Kusunose, M; Yamamoto, S | 1 |
| Elcombe, CR; Elliott, BM | 1 |
| Lalwani, ND; Rao, MS; Reddy, JK; Reddy, MK; Usman, MI | 1 |
| Bridges, JW; Hinton, RH; Mitchell, FE | 1 |
| Gangolli, SD; Gray, TJ; Lake, BG | 1 |
| Earley, K; Goel, SK; Gupta, RC; Reddy, JK; Singh, B | 1 |
| Bridges, JW; Hall, DE; Hinton, RH; Mann, A; Mitchell, FE; Price, SC | 1 |
| Gray, TJ; Lake, BG | 1 |
| Furuta, S; Hashimoto, T; Miyazawa, S | 2 |
| Jirtle, RL; Michalopoulos, G; Qureshi, SA; Reddy, JK; Reddy, NK; Watanabe, TK | 1 |
| Gangolli, SD; Gray, TJ; Hodder, KD; Lake, BG; Stubberfield, CR; Tredger, JM; Williams, R | 1 |
| Fukui, K; Hayashi, H; Yamasaki, F | 1 |
| Foster, JR; Gangolli, SD; Gray, TJ; Lake, BG; Rijcken, WR | 1 |
| Beamand, JA; Foster, JR; Gangolli, SD; Gray, TJ; Lake, BG | 2 |
| Ishigami, M; Loo, Y; Sano, K; Sasaki, M; Shin, M; Umezawa, C; Yamashita, Y | 1 |
| Aberg, F; Appelkvist, EL | 1 |
| Clack, JW; Jarnot, BM; Witzmann, FA | 1 |
| Byers, DM; Cook, HW; Palmer, FB; Thorne, PC | 1 |
| Aldridge, TC; Green, S; Issemann, I; Prince, RA; Tugwood, JD | 1 |
| Baldwin, LA; Calabrese, EJ; Leonard, DA; Wysynski, AM | 1 |
| Aberg, F; Appelkvist, EL; Dallner, G; Zhang, Y | 1 |
| Castle, PJ; Okita, JR; Okita, RT | 1 |
| Kato, N; Sasago, S; Satoh, A; Takahashi, S | 1 |
| Barrett, JC; Tsutsui, T; Watanabe, E | 1 |
| Coughtrie, M; Fultz, C; Lipscomb, J; Witzmann, F | 1 |
| Fitzpatrick, DR; Germain-Lee, E; Jimenez-Sanchez, G; Valle, D | 1 |
| Gonzalez, FJ; Motojima, K; Peters, JM | 1 |
| Alexson, SE; Aoyama, T; Engberg, ST; Hashimoto, T; Svensson, LT | 1 |
| Brady, EP; Chandar, N; Eagon, PK; Elm, MS; Kelly, RH; Rao, B; Rao, KN; Shinozuka, H | 1 |
| Becedas, L; Bengtsson Ahlberg, M; Georgellis, A; Lundqvist, G; Mehrotra, K; Morgenstern, R | 1 |
| Cruciani, V; Mikalsen, SO; Sanner, T; Vasseur, P | 1 |
| Mock, DM; Mock, NI; Wang, KS | 1 |
| Gill, SS; Muhlenkamp, CR | 1 |
| Cajaraville, MP; Cancio, I; Fahimi, HD; Orbea, A; Völkl, A | 1 |
| Katoh, M; Kidachi, F; Kurata, Y; Toyota, N; Tsuchitani, M; Yokoyama, M | 1 |
| Gonzalez, FJ; Latruffe, N; Motojima, K; Passilly, P; Peters, JM | 1 |
| Amichot, M; Bergé, JB; Cuany, A; de Sousa, G; Girard, JP; Lafaurie, M; Rahmani, R; Sabourault, C; Salaün, JP | 1 |
| Wallace, KB; Zhou, S | 1 |
| Dallner, G; Sindelar, P; Turunen, M | 1 |
| Hagiwara, A; Hasegawa, R; Imaida, K; Ito, N; Sano, M; Shirai, T; Tamano, S | 1 |
| Hall, M; Harling, R; Matthews, A; Webley, L | 1 |
| Asayama, K; Dobashi, K; Hayashibe, H; Kodera, K; Nakane, T; Nakazawa, S; Uchida, N | 1 |
| Brown, WJ; de Figueiredo, P | 1 |
| Ackley, DC; Brown, R; Clare, LJ; Isenberg, JS; Kamendulis, LM; Klaunig, JE; Lington, AW; Pugh, G; Smith, JH | 1 |
| Hamano, T; Hayashi, M; Kobayashi, K; Mutai, M; Sakairi, T | 1 |
| Chen, P; Colet, JM; Estrem, ST; Gao, H; Goldstein, KM; Huang, S; Jolly, RA; Ryan, TP; Thomas, CE; Wei, T | 1 |
| Randić, M | 1 |
| Aleksunes, LM; Corton, JC; George, MH; Klaassen, CD; Ren, H; Vallanat, B; Wood, C | 1 |
| Cho, WS; Choi, M; Han, BS; Jeong, J; Park, SN; Son, WC | 1 |
2 review(s) available for diethylhexyl phthalate and clofibrate
| Article | Year |
|---|---|
Delineating peroxisome proliferator action to improve human risk assessment.
Topics: Acyl-CoA Oxidase; Animals; Base Sequence; Clofibrate; Cloning, Molecular; Diethylhexyl Phthalate; DNA; Fatty Acids; Humans; Liver; Liver Neoplasms, Experimental; Mice; Microbodies; Molecular Sequence Data; Oxidoreductases; Promoter Regions, Genetic; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Risk Assessment; Transcription Factors; Tretinoin | 1994 |
Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.
Topics: Animals; Clofibrate; Constitutive Androstane Receptor; Diethylhexyl Phthalate; Gene Expression Profiling; Gene Expression Regulation; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Peroxisome Proliferators; Phenobarbital; Plasticizers; PPAR alpha; Pregnane X Receptor; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Valproic Acid | 2010 |
81 other study(ies) available for diethylhexyl phthalate and clofibrate
| Article | Year |
|---|---|
Effects of modifying agents on conformity of enzyme phenotype and proliferative potential in focal preneoplastic and neoplastic liver cell lesions in rats.
Topics: Adenosine Triphosphatases; Animals; Bromodeoxyuridine; Cell Division; Clofibrate; Diethylhexyl Phthalate; Diethylnitrosamine; Ethoxyquin; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glutathione Transferase; Isoenzymes; Liver Neoplasms, Experimental; Male; Phenobarbital; Phenotype; Precancerous Conditions; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 1992 |
Effects of joint exposures to selected peroxisome proliferators on hepatic acyl-CoA oxidase activity in male B6C3F1 mice.
Topics: Acyl-CoA Oxidase; Animals; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Fibric Acids; Hypolipidemic Agents; Liver; Male; Mice; Mice, Inbred Strains; Microbodies; Oxidoreductases | 1992 |
Peroxisome proliferators protect against paracetamol hepatotoxicity in mice.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Acetaminophen; Alanine Transaminase; Animals; Benzoquinones; Clofibrate; Diethylhexyl Phthalate; Glutathione; Imines; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Liver; Male; Mice; Microbodies; Oxidation-Reduction | 1992 |
Involvement of calmodulin- and protein kinase C-related mechanism in an induction process of peroxisomal fatty acid oxidation-related enzymes by hypolipidemic peroxisome proliferators.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bezafibrate; Body Weight; Calmodulin; Catalase; Cells, Cultured; Clofibrate; Diethylhexyl Phthalate; Electrophoresis, Polyacrylamide Gel; Isoquinolines; Kinetics; Liver; Male; Membrane Proteins; Microbodies; Molecular Weight; Organ Size; Oxidation-Reduction; Piperazines; Protein Kinase C; Pyrimidines; Rats; Rats, Inbred Strains; Reference Values; Trifluoperazine | 1992 |
Induction protocols for the cytochrome P450IVA subfamily in animals and primary hepatocyte cultures.
Topics: Animals; Cells, Cultured; Clofibrate; Clofibric Acid; Culture Techniques; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Enzyme Induction; Fibric Acids; Genetic Techniques; Isoenzymes; Liver; Rats; Rats, Inbred Strains; RNA, Messenger; Species Specificity; Transcription, Genetic | 1991 |
Lack of induction of hepatic DNA damage on long-term administration of peroxisome proliferators in male F-344 rats.
Topics: Animals; Bezafibrate; Clofibrate; Diethylhexyl Phthalate; DNA Damage; DNA, Single-Stranded; Lipid Peroxidation; Liver; Male; Oxidation-Reduction; Rats; Rats, Inbred F344 | 1991 |
Hepatic peroxisome proliferators induce morphologic transformation of Syrian hamster embryo cells, but not peroxisomal beta oxidation.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Digitonin; Embryo, Mammalian; Fatty Alcohols; Hypolipidemic Agents; Liver; Mesocricetus; Microbodies; Nicotinic Acids; Rats; Tetradecanoylphorbol Acetate | 1991 |
Quantitative changes in sets of proteins as markers of biological response.
Topics: Animals; Biomarkers; Carcinogens; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Electrophoresis, Gel, Two-Dimensional; Fibric Acids; Liver; Liver Neoplasms, Experimental; Male; Mice; Proteins; Pyrimidines | 1991 |
Promoting effect of the peroxisome proliferator, clofibrate, but not di(2-ethylhexyl)phthalate, on urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Clofibrate; Diethylhexyl Phthalate; DNA, Neoplasm; Liver; Male; Organ Size; Rats; Rats, Inbred F344; Uracil; Urinary Bladder Neoplasms | 1990 |
Role of catalase and oxidative stress in hepatic peroxisome proliferator-induced morphological transformation of Syrian hamster embryo cells.
Topics: Amitrole; Animals; Catalase; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Electron Spin Resonance Spectroscopy; Fatty Alcohols; Hydrogen Peroxide; Liver; Mesocricetus; Microbodies; Vitamin K | 1990 |
Alterations in the integrity of peroxisomal membranes in livers of mice treated with peroxisome proliferators.
Topics: Animals; Catalase; Clofibrate; Diethylhexyl Phthalate; Female; Mice; Microbodies; Mitochondria, Liver; Pyrimidines; Sonication | 1990 |
Effects of hepatic peroxisome proliferators and 12-O-tetradecanoyl phorbol-13-acetate on catalase and other enzyme activities of embryonic cells in vitro.
Topics: 2,4-Dichlorophenoxyacetic Acid; Acyl-CoA Oxidase; Animals; Catalase; Cells, Cultured; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Digitonin; Embryo, Mammalian; Enzyme Induction; Liver; Male; Mesocricetus; Microbodies; Oxidation-Reduction; Oxidoreductases; Rats; Rats, Inbred Strains; Rats, Inbred WKY | 1990 |
The effects of inducers of the endoplasmic reticulum, peroxisomes and mitochondria on the amounts and synthesis of ubiquinone in rat liver subcellular membranes.
Topics: Animals; Cholesterol, Dietary; Cholestyramine Resin; Chromatography, High Pressure Liquid; Clofibrate; Diethylhexyl Phthalate; Diethylnitrosamine; Dolichols; Endoplasmic Reticulum; Intracellular Membranes; Liver; Methylcholanthrene; Mevalonic Acid; Microbodies; Microsomes, Liver; Mitochondria, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Ubiquinone | 1990 |
Morphological transformation and catalase activity of Syrian hamster embryo cells treated with hepatic peroxisome proliferators, TPA and nickel sulphate.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Catalase; Cells, Cultured; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Embryo, Mammalian; Fatty Alcohols; Hypolipidemic Agents; Nickel; Phthalic Acids; Tetradecanoylphorbol Acetate | 1990 |
Relationship between hepatic peroxisome proliferation and 8-hydroxydeoxyguanosine formation in liver DNA of rats following long-term exposure to three peroxisome proliferators; di(2-ethylhexyl) phthalate, aluminium clofibrate and simfibrate.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aluminum; Animals; Catalase; Clofibrate; Death; Deoxyguanosine; Diethylhexyl Phthalate; DNA; DNA Damage; Hypolipidemic Agents; Kidney; Liver; Male; Microbodies; Oxidation-Reduction; Phthalic Acids; Rats; Time Factors | 1990 |
Long-term effects of peroxisome proliferators on the balance between hydrogen peroxide-generating and scavenging capacities in the liver of Fischer-344 rats.
Topics: Acyl-CoA Oxidase; Animals; Bezafibrate; Cells, Cultured; Clofibrate; Cytosol; Diethylhexyl Phthalate; Enzyme Activation; Hydrogen Peroxide; Liver; Liver Neoplasms, Experimental; Male; Microbodies; Microscopy, Electron; Oxidoreductases; Phthalic Acids; Rats; Rats, Inbred F344; Time Factors | 1990 |
Peroxisome proliferator-induced alterations in the expression and modification of rat hepatocyte plasma membrane proteins.
Topics: Antibodies, Monoclonal; Asialoglycoprotein Receptor; Blotting, Western; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; ErbB Receptors; Fibric Acids; Fluorescent Antibody Technique; Isoelectric Point; Liver; Membrane Glycoproteins; Microbodies; Pyrimidines; Receptors, Immunologic; Sialoglycoproteins | 1990 |
Immunocytochemical localization of delta 3, delta 2-enoyl-CoA isomerase in rat liver. The effects of di-(2-ethylhexyl)phthalate, a peroxisome proliferator.
Topics: Animals; Antibody Specificity; Carbon-Carbon Double Bond Isomerases; Clofibrate; Diethylhexyl Phthalate; Dodecenoyl-CoA Isomerase; Immunohistochemistry; Isomerases; Liver; Microscopy; Microscopy, Electron; Phthalic Acids; Rats | 1989 |
Identity of acyl-CoA oxidase with glutaryl-CoA oxidase.
Topics: Acyl-CoA Oxidase; Animals; Clofibrate; Diethylhexyl Phthalate; Electrophoresis, Polyacrylamide Gel; Liver; Male; Mitochondria, Liver; Oxidoreductases; Rats; Rats, Inbred Strains; Solubility; Sulfates; Zinc; Zinc Sulfate | 1989 |
Existence of acetyl-CoA-dependent chain elongation system in hepatic peroxisomes of rat: effects of clofibrate and di-(2-ethylhexyl)phthalate on the activity.
Topics: Acetyl Coenzyme A; Acyl-CoA Dehydrogenases; Animals; Cell Fractionation; Centrifugation, Density Gradient; Clofibrate; Diethylhexyl Phthalate; Fatty Acid Desaturases; Fatty Acids; Kinetics; Liver; Male; Malonyl Coenzyme A; Microbodies; Phthalic Acids; Rats; Rats, Inbred Strains; Reference Values | 1989 |
Co-ordinate induction of hepatic mitochondrial and peroxisomal carnitine acyltransferase synthesis by diet and drugs.
Topics: Acyltransferases; Animals; Aspirin; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Clofibrate; Dietary Fats; Diethylhexyl Phthalate; Liver; Male; Microbodies; Mitochondria, Liver; Rats; Rats, Inbred Strains | 1989 |
Lack of hepatic promotional activity by the peroxisomal proliferating hepatocarcinogen di(2-ethylhexyl)phthalate.
Topics: Animals; Cell Division; Clofibrate; Diethylhexyl Phthalate; Diethylnitrosamine; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Microbodies; Phthalic Acids; Rats; Rats, Inbred Strains | 1985 |
Mitochondrial acetyl-CoA acetyltransferase in liver and extrahepatic tissues: role of modification by coenzyme A.
Topics: Acetyl-CoA C-Acetyltransferase; Acetyltransferases; Animals; Brain; Clofibrate; Coenzyme A; Diethylhexyl Phthalate; Immunoelectrophoresis; Ketone Bodies; Kidney; Kinetics; Male; Mitochondria; Mitochondria, Liver; Myocardium; Phthalic Acids; Rats; Rats, Inbred Strains | 1986 |
Effects of clofibrate and acetylsalicylic acid on hepatic carnitine palmitoyltransferase synthesis.
Topics: Acyltransferases; Animals; Aspirin; Carnitine O-Palmitoyltransferase; Clofibrate; Diethylhexyl Phthalate; Glucagon; Liver; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic | 1989 |
Changes to the integral membrane protein composition of mouse liver peroxisomes in response to the peroxisome proliferators clofibrate, Wy-14,643 and di(2-ethyl-hexyl)phthalate.
Topics: Animals; Antineoplastic Agents; Catalase; Clofibrate; Diethylhexyl Phthalate; Liver; Membrane Proteins; Mice; Microbodies; Oxidation-Reduction; Phthalic Acids; Pyrimidines | 1988 |
Promoting effect of peroxisome proliferators in two-stage rat renal tumorigenesis.
Topics: Animals; Clofibrate; Cocarcinogenesis; Diethylhexyl Phthalate; Diethylnitrosamine; Kidney Neoplasms; Male; Microbodies; Rats; Rats, Inbred F344 | 1988 |
Hepatic epoxide hydrolase activities and their induction by clofibrate and diethylhexylphthalate in various strains of mice.
Topics: Animals; Clofibrate; Cytosol; Diethylhexyl Phthalate; Enzyme Induction; Epoxide Hydrolases; Immunosorbent Techniques; Liver; Mice; Mice, Inbred Strains; Phthalic Acids | 1987 |
Alterations in the thyroids of rats treated for long periods with di-(2-ethylhexyl) phthalate or with hypolipidaemic agents.
Topics: Animals; Clofibrate; Diethylhexyl Phthalate; Electron Probe Microanalysis; Fenofibrate; Iodine; Lysosomes; Microscopy, Electron; Phthalic Acids; Plasticizers; Propionates; Rats; Thyroid Gland; Time Factors | 1988 |
Co-induction of microsomal cytochrome P-452 and the peroxisomal fatty acid beta-oxidation pathway in the rat by clofibrate and di-(2-ethylhexyl)phthalate. Dose-response studies.
Topics: Animals; Clofibrate; Cytochromes; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Enzyme Induction; Fatty Acids; Liver; Male; Microbodies; Microsomes, Liver; Oxidation-Reduction; Phthalic Acids; Rats; Rats, Inbred Strains | 1988 |
Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acyl-CoA Oxidase; Animals; Catalase; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Enoyl-CoA Hydratase; Fibric Acids; Hydro-Lyases; Immunoelectrophoresis; Isomerases; Liver; Male; Microbodies; Multienzyme Complexes; Oxidoreductases; Peroxisomal Bifunctional Enzyme; Rats; Rats, Inbred F344; RNA, Messenger; Transcription, Genetic | 1986 |
Induction of peroxisome proliferation in hepatocytes transplanted into the anterior chamber of the eye. A model system for the evaluation of xenobiotic-induced effects.
Topics: Animals; Anterior Chamber; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Fibric Acids; Fluorescent Antibody Technique; Liver; Liver Transplantation; Male; Microbodies; Phthalic Acids; Rats; Rats, Inbred F344 | 1986 |
Effect of prolonged administration of clofibric acid and di-(2-ethylhexyl)phthalate on hepatic enzyme activities and lipid peroxidation in the rat.
Topics: Animals; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Hepatomegaly; Lipid Peroxides; Liver; Male; Microbodies; Phthalic Acids; Rats; Rats, Inbred Strains | 1987 |
Effect of peroxisomal proliferators on microsomal prostaglandin A omega-hydroxylase.
Topics: Animals; Clofibrate; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Enzyme Activation; Immunochemistry; Intestine, Small; Kidney Cortex; Microbodies; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phthalic Acids; Rabbits | 1986 |
Lack of DNA damage or lipid peroxidation measured in vivo in the rat liver following treatment with peroxisomal proliferators.
Topics: Animals; Cell Division; Clofenapate; Clofibrate; Diethylhexyl Phthalate; DNA Damage; Female; Glutathione Peroxidase; Lipid Peroxides; Liver; Male; Microbodies; Rats; Rats, Inbred F344; Superoxide Dismutase | 1987 |
Comparison of hepatic peroxisome proliferative effect and its implication for hepatocarcinogenicity of phthalate esters, di(2-ethylhexyl) phthalate, and di(2-ethylhexyl) adipate with a hypolipidemic drug.
Topics: Adipates; Animals; Catalase; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Fibric Acids; Liver; Liver Neoplasms, Experimental; Microbodies; Microscopy, Electron; Oxidation-Reduction; Phthalic Acids; Rats; Structure-Activity Relationship | 1986 |
Effects of mono (2-ethylhexyl) phthalate and its straight chain analogues mono-n-hexylphthalate and mono-n-octyl phthalate on lipid metabolism in isolated hepatocytes.
Topics: Animals; Cells, Cultured; Clofibrate; Diethylhexyl Phthalate; Lipid Metabolism; Lipoproteins; Liver; Male; Microbodies; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Phthalic Acids; Rats; Rats, Inbred Strains; Triglycerides | 1986 |
Hepatic effects of phthalate esters and related compounds--in vivo and in vitro correlations.
Topics: Animals; Cells, Cultured; Clofibrate; Cricetinae; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Guinea Pigs; Liver; Male; Microbodies; Microsomes, Liver; Palmitoyl Coenzyme A; Phthalic Acids; Rats; Species Specificity; Structure-Activity Relationship | 1986 |
32P-postlabeling analysis of peroxisome proliferator-DNA adduct formation in rat liver in vivo and hepatocytes in vitro.
Topics: Animals; Anticholesteremic Agents; Carcinogens; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; DNA; Fibric Acids; Hypolipidemic Agents; In Vitro Techniques; Liver; Liver Neoplasms; Male; Microbodies; Phosphorus Radioisotopes; Pyrimidines; Rats | 1985 |
Plasma protein changes in rats treated with hypolipidaemic drugs and with phthalate esters.
Topics: Animals; Blood Proteins; Clofibrate; Diet; Diethylhexyl Phthalate; Fenofibrate; Haptoglobins; Hypolipidemic Agents; Immunoelectrophoresis; Male; Phthalic Acids; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Species differences in hepatic peroxisome proliferation.
Topics: Animals; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Dogs; Female; Humans; Liver; Male; Mice; Microbodies; Rats; Species Specificity | 1985 |
Induction of a novel long-chain acyl-CoA hydrolase in rat liver by administration of peroxisome proliferators.
Topics: Animals; Aspirin; Clofibrate; Diethylhexyl Phthalate; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Liver; Male; Molecular Weight; Octoxynol; Palmitoyl-CoA Hydrolase; Phthalic Acids; Polyethylene Glycols; Rats; Serum Albumin, Bovine; Thiolester Hydrolases | 1981 |
Response of hepatocytes transplanted into syngeneic hosts and heterotransplanted into athymic nude mice to peroxisome proliferators.
Topics: Animals; Clofibrate; Diethylhexyl Phthalate; Liver; Liver Transplantation; Male; Mice; Mice, Nude; Microbodies; Microscopy, Electron; Phthalic Acids; Rats; Rats, Inbred F344; Transplantation, Heterologous; Transplantation, Isogeneic | 1984 |
The effect of peroxisome proliferators on the metabolism and spectral interaction of endogenous substrates of cytochrome P-450 in rat hepatic microsomes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Hydroxylation; Linoleic Acid; Linoleic Acids; Male; Microbodies; Microsomes, Liver; Phthalic Acids; Rats; Rats, Inbred Strains; Testosterone | 1984 |
Association of the liver peroxisomal fatty acyl-CoA beta-oxidation system with the synthesis of bile acids.
Topics: Acyl Coenzyme A; Amitrole; Animals; Bile; Bile Acids and Salts; Cholesterol; Clofibrate; Diethylhexyl Phthalate; Hypolipidemic Agents; In Vitro Techniques; Liver; Male; Microbodies; Mitochondria, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1984 |
Comparative studies of the hepatic effects of di- and mono-n-octyl phthalates, di-(2-ethylhexyl) phthalate and clofibrate in the rat.
Topics: Animals; Clofibrate; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Liver; Male; Microbodies; Mixed Function Oxygenases; Phthalic Acids; Rats; Rats, Inbred Strains | 1984 |
Peroxisome proliferation in primary cultures of rat hepatocytes.
Topics: Animals; Carnitine O-Acetyltransferase; Cell Division; Cells, Cultured; Clofibrate; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; In Vitro Techniques; Liver; Male; Microbodies; Organoids; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains | 1983 |
Peroxisome proliferation in cultured rat hepatocytes produced by clofibrate and phthalate ester metabolites.
Topics: Animals; Carnitine O-Acetyltransferase; Cells, Cultured; Clofibrate; Diethylhexyl Phthalate; Enzyme Induction; Hexanols; Liver; Male; Microbodies; Organoids; Phthalic Acids; Rats; Rats, Inbred Strains | 1982 |
Induction of acyl-CoA dehydrogenases and electron transfer flavoprotein and their roles in fatty acid oxidation in rat liver mitochondria.
Topics: Animals; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Enzyme Induction; Fatty Acid Desaturases; Fatty Acids; Flavoproteins; Microbodies; Mitochondria, Liver; Phthalic Acids; Rats | 1981 |
Effect of feeding clofibrate-containing diet on the hepatic NAD+ level in rats.
Topics: Animals; Clofibrate; Diet; Diethylhexyl Phthalate; Fenofibrate; Hypolipidemic Agents; Liver; Male; Microbodies; NAD; Rats; Rats, Sprague-Dawley | 1995 |
Clofibrate and di(2-ethylhexyl)phthalate increase ubiquinone contents without affecting cholesterol levels.
Topics: Animals; Brain; Cholesterol; Clofibrate; Diet; Diethylhexyl Phthalate; Dolichols; Heart; Liver; Muscles; Myocardium; Organ Specificity; Rats; Rats, Sprague-Dawley; Ubiquinone | 1994 |
Charge modification in rodent hepatic Grp78/BiP following exposure to structurally diverse peroxisome proliferators.
Topics: Animals; Caprylates; Carrier Proteins; Clofibrate; Decanoic Acids; Diethylhexyl Phthalate; Electrochemistry; Electrophoresis, Gel, Two-Dimensional; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Fluorocarbons; Heat-Shock Proteins; Liver; Male; Microbodies; Molecular Chaperones; Phosphorylation; Protein Folding; Rats; Rats, Inbred F344 | 1994 |
Clofibrate and other peroxisomal proliferating agents relatively specifically inhibit synthesis of ethanolamine phosphoglycerides in cultured human fibroblasts.
Topics: Cells, Cultured; Choline; Clofibrate; Diethylhexyl Phthalate; Ethanolamine; Ethanolamines; Fatty Alcohols; Humans; Linolenic Acids; Microbodies; Phosphatidylethanolamines; Plasmalogens; Pyrimidines | 1994 |
Interactive potential of omega-3 fatty acids with clofibrate or DEHP on hepatic peroxisome proliferation in male Wistar rats.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acyl-CoA Oxidase; Animals; Body Weight; Cell Division; Clofibrate; Dietary Fats; Diethylhexyl Phthalate; Enoyl-CoA Hydratase; Fatty Acids, Omega-3; Isomerases; Liver; Male; Microbodies; Multienzyme Complexes; Organ Size; Oxidoreductases; Peroxisomal Bifunctional Enzyme; Rats; Rats, Wistar | 1993 |
Effects of clofibrate, phthalates and probucol on ubiquinone levels.
Topics: Animals; Brain; Cholesterol; Chromatography, High Pressure Liquid; Clofibrate; Diet; Diethylhexyl Phthalate; Dolichols; Liver; Male; Mevalonic Acid; Muscles; Myocardium; Oxidation-Reduction; Probucol; Rats; Rats, Sprague-Dawley; Ubiquinone | 1994 |
Characterization of cytochromes P450 in liver and kidney of rats treated with di-(2-ethylhexyl)phthalate.
Topics: Animals; Antibody Specificity; Blotting, Western; Clofibrate; Cross Reactions; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Eicosanoids; Fatty Acids; Female; Hydroxylation; In Vitro Techniques; Kidney; Liver; Male; Microsomes; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Sex Characteristics | 1993 |
Regulation of xanthine dehydrogenase in rat liver in response to peroxisome proliferators.
Topics: Animals; Bezafibrate; Blotting, Western; Caprylates; Catalase; Clofibrate; Dehydroepiandrosterone; Diethylhexyl Phthalate; Fluorocarbons; Kinetics; Liver; Male; Microbodies; Rats; Rats, Wistar; Xanthine Dehydrogenase | 1993 |
Ability of peroxisome proliferators to induce cell transformation, chromosome aberrations and peroxisome proliferation in cultured Syrian hamster embryo cells.
Topics: Animals; Benzidines; Cell Transformation, Neoplastic; Chromosome Aberrations; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Mesocricetus; Microbodies; Pyrimidines | 1993 |
Effect of structurally diverse peroxisome proliferators on rat hepatic sulfotransferase.
Topics: Amino Acid Sequence; Animals; Caprylates; Clofibrate; Decanoic Acids; Diethylhexyl Phthalate; Electrophoresis, Gel, Two-Dimensional; Fluorocarbons; Liver; Male; Microbodies; Molecular Sequence Data; Rats; Rats, Inbred F344; Sulfotransferases | 1996 |
Characterization of a cDNA library enriched for a novel peroxisomal gene.
Topics: Animals; Base Sequence; Clofibrate; Cloning, Molecular; Diethylhexyl Phthalate; DNA, Complementary; Gene Expression Regulation, Enzymologic; Gene Library; Genes; Hypolipidemic Agents; Microbodies; Molecular Sequence Data; Rats; Up-Regulation | 1996 |
PPAR alpha mediates peroxisome proliferator-induced transcriptional repression of nonperoxisomal gene expression in mouse.
Topics: Alpha-Globulins; Animals; Clofibrate; Diethylhexyl Phthalate; Gene Expression Regulation; Kinetics; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Mice, Knockout; Microbodies; Nuclear Proteins; Prealbumin; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Species Specificity; Time Factors; Transcription Factors; Transcription, Genetic | 1997 |
Peroxisome proliferator-induced acyl-CoA thioesterase from rat liver cytosol: molecular cloning and functional expression in Chinese hamster ovary cells.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; CHO Cells; Clofibrate; Cloning, Molecular; Cricetinae; Diethylhexyl Phthalate; DNA, Complementary; Isoenzymes; Liver; Male; Microbodies; Molecular Sequence Data; Palmitoyl-CoA Hydrolase; Rats; Rats, Sprague-Dawley; Restriction Mapping; Sequence Homology, Nucleic Acid | 1997 |
Hepatic hyperplasia and cancer in rats: metabolic alterations associated with cell growth.
Topics: Animals; Blotting, Western; Carcinogens; Cell Division; Cholesterol; Clofibrate; Diethylhexyl Phthalate; Glucosephosphate Dehydrogenase; Hydroxymethylglutaryl CoA Reductases; Hyperplasia; Liver; Liver Neoplasms, Experimental; Malate Dehydrogenase; Male; NADP; Pentose Phosphate Pathway; Pyrimidines; Rats; Rats, Inbred F344; Receptors, LDL; RNA, Messenger | 1997 |
Effects of peroxisome proliferators and/or hypothyroidism on xenobiotic-metabolizing enzymes in rat testis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arylsulfotransferase; Aspirin; Caprylates; Catalase; Clofibrate; Diet; Diethylhexyl Phthalate; Disease Models, Animal; Epoxide Hydrolases; Fluorocarbons; Glucuronosyltransferase; Glutathione Peroxidase; Glutathione Transferase; Hypolipidemic Agents; Hypothyroidism; Male; Microbodies; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Testis | 1997 |
Effects of peroxisome proliferators and 12-O-tetradecanoyl phorbol-13-acetate on intercellular communication and connexin43 in two hamster fibroblast systems.
Topics: Animals; Blotting, Western; Carcinogens; Cell Communication; Cells, Cultured; Clofenapate; Clofibrate; Connexin 43; Cricetinae; Cricetulus; Diethylhexyl Phthalate; Fibroblasts; Gap Junctions; Hypolipidemic Agents; Liver; Lung; Microbodies; Phosphorylation; Tetradecanoylphorbol Acetate | 1997 |
Biotin biotransformation to bisnorbiotin is accelerated by several peroxisome proliferators and steroid hormones in rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Biotin; Biotransformation; Carbamazepine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Clofibrate; Dehydroepiandrosterone; Dexamethasone; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Male; Microbodies; Phenobarbital; Phenytoin; Radiometry; Rats; Rats, Sprague-Dawley; Steroids | 1997 |
A glucose-regulated protein, GRP58, is down-regulated in C57B6 mouse liver after diethylhexyl phthalate exposure.
Topics: Animals; Base Sequence; Body Weight; Clofibrate; Diethylhexyl Phthalate; DNA Primers; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Endoplasmic Reticulum; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Isomerases; Liver; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Organ Size; Polymerase Chain Reaction; Protein Disulfide-Isomerases; RNA, Messenger; Sequence Analysis, DNA | 1998 |
Induction of peroxisomal oxidases in mussels: comparison of effects of lubricant oil and benzo(a)pyrene with two typical peroxisome proliferators on peroxisome structure and function in Mytilus galloprovincialis.
Topics: Animals; Benzo(a)pyrene; Biomarkers; Bivalvia; Catalase; Clofibrate; D-Amino-Acid Oxidase; Diethylhexyl Phthalate; Environmental Monitoring; Enzyme Induction; Oxidoreductases; Petroleum; Water Pollutants, Chemical | 1998 |
Subchronic toxicity of Di(2-ethylhexyl)phthalate in common marmosets: lack of hepatic peroxisome proliferation, testicular atrophy, or pancreatic acinar cell hyperplasia.
Topics: Animals; Callithrix; Clofibrate; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Female; Liver; Male; Microbodies; Organ Size; Pancreas; Species Specificity; Testis; Toxicity Tests | 1998 |
Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner.
Topics: Adipates; Adipose Tissue; Animals; Base Sequence; CD36 Antigens; Clofibrate; Diethylhexyl Phthalate; DNA Primers; Gene Expression Regulation; Liver; Liver Neoplasms, Experimental; Male; Membrane Glycoproteins; Mice; Microbodies; Organic Anion Transporters; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured | 1998 |
Tissue-specific induction and inactivation of cytochrome P450 catalysing lauric acid hydroxylation in the sea bass, Dicentrarchus labrax.
Topics: Animals; Bass; Biomarkers; Clofibrate; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Fatty Acids, Unsaturated; Hydroxylation; Intestine, Small; Kidney; Kinetics; Lauric Acids; Liver; Microsomes; Organ Specificity; Peroxisome Proliferators; Substrate Specificity | 1999 |
The effect of peroxisome proliferators on mitochondrial bioenergetics.
Topics: Animals; Bezafibrate; Calcium; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Energy Metabolism; Fenofibrate; Fibric Acids; Gemfibrozil; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Oxygen; Permeability; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Sprague-Dawley; Trichloroethylene | 1999 |
Induction of endogenous coenzyme Q biosynthesis by administration of peroxisomal inducers.
Topics: Aging; Animals; Aspirin; Clofibrate; Dehydroepiandrosterone; Diethylhexyl Phthalate; Intracellular Membranes; Liver; Male; Microbodies; Mitochondria, Liver; Organ Specificity; Organelles; Peroxisome Proliferators; Rats; Rats, Sprague-Dawley; Ubiquinone | 1999 |
Dose-dependent induction of carcinomas and glutathione S-transferase placental form negative eosinophilic foci in the rat liver by di(2-ethylhexyl)phthalate after diethylnitrosamine initiation.
Topics: Adenoma, Liver Cell; Animals; Body Weight; Carcinoma, Hepatocellular; Clofibrate; Cocarcinogenesis; Diethylhexyl Phthalate; Dimethylnitrosamine; Dose-Response Relationship, Drug; Glutathione S-Transferase pi; Glutathione Transferase; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; No-Observed-Adverse-Effect Level; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Effects of di-isononyl phthalate (DINP) on peroxisomal markers in the marmoset-DINP is not a peroxisome proliferator.
Topics: Animals; Biomarkers; Callithrix; Cell Fractionation; Clofibrate; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Female; Kidney; Liver; Male; Membrane Proteins; Microbodies; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Peroxisome Proliferators; Phthalic Acids; Salivary Glands; Toxicity Tests; Weight Gain | 1999 |
Effect of peroxisome proliferator on extracellular glutathione peroxidase in rat.
Topics: Aldehydes; Animals; Blotting, Northern; Body Weight; Catalase; Clofibrate; Diethylhexyl Phthalate; Extracellular Matrix; Free Radicals; Glutathione Peroxidase; Immunoblotting; Kidney; Lipid Peroxides; Liver; Male; Organ Size; Peroxisome Proliferators; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Staining and Labeling | 1999 |
Clofibrate inhibits membrane trafficking to the Golgi complex and induces its retrograde movement to the endoplasmic reticulum.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cells, Cultured; Clofibrate; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Endoplasmic Reticulum; Fatty Acids; Fluorescent Antibody Technique; Golgi Apparatus; Hypolipidemic Agents; Liver; Mannosidases; Membrane Glycoproteins; Microtubules; Nocodazole; Peroxisome Proliferators; Peroxisomes; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Viral Envelope Proteins | 1999 |
Effects of di-isononyl phthalate, di-2-ethylhexyl phthalate, and clofibrate in cynomolgus monkeys.
Topics: Administration, Oral; Animals; Anticholesteremic Agents; Body Weight; Cell Communication; Clofibrate; Diethylhexyl Phthalate; DNA Replication; Gap Junctions; Liver; Macaca fascicularis; Organ Size; Oxidation-Reduction; Peroxisome Proliferators; Peroxisomes; Phthalic Acids | 2000 |
Peroxisome proliferator-activated receptor alpha (PPAR alpha) agonist, WY-14,643, increased transcription of myosin light chain-2 in cardiomyocytes.
Topics: Animals; Body Weight; Cardiac Myosins; Cell Line; Clofibrate; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Heart; Immunohistochemistry; Male; Myocardium; Myosin Light Chains; Organ Size; Peroxisome Proliferators; Proteins; Pyrimidines; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transcription, Genetic | 2001 |
Pooling samples within microarray studies: a comparative analysis of rat liver transcription response to prototypical toxicants.
Topics: Animals; Clofibrate; Cluster Analysis; Diethylhexyl Phthalate; Fatty Acids; Gene Expression; Gene Expression Profiling; Gene Expression Regulation; Liver; Liver Extracts; Male; Mitochondria; Models, Biological; Models, Statistical; Oligonucleotide Array Sequence Analysis; Organ Size; Phenotype; Phylogeny; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Transcription, Genetic; Valproic Acid | 2005 |
Quantitative characterizations of proteome: dependence on the number of proteins considered.
Topics: Animals; Caprylates; Clofibrate; Decanoic Acids; Diethylhexyl Phthalate; Fluorocarbons; Hepatocytes; Mice; Peptide Mapping; Peroxisome Proliferators; Proteome; Proteomics; Sensitivity and Specificity | 2006 |
26-Week carcinogenicity study of di-isodecyl phthalate by dietary administration to CB6F1-rasH2 transgenic mice.
Topics: Adenoma, Liver Cell; Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; Clofibrate; Diethylhexyl Phthalate; Disease Models, Animal; Female; Genes, ras; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Mice; Mice, Transgenic; Phthalic Acids; Pyrimidines; Time Factors | 2011 |