diethyl pyrocarbonate has been researched along with histidine in 503 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 195 (38.77) | 18.7374 |
| 1990's | 229 (45.53) | 18.2507 |
| 2000's | 70 (13.92) | 29.6817 |
| 2010's | 6 (1.19) | 24.3611 |
| 2020's | 3 (0.60) | 2.80 |
| Authors | Studies |
|---|---|
| Sano, S; Tsukamoto, I; Yoshinaga, T | 1 |
| Gaudemer, Y; Latruffe, N | 1 |
| Allsopp, SR; Homer, RB | 1 |
| Hiwatashi, A; Ichikawa, Y; Maruya, N; Yamano, T | 1 |
| Llosa, P | 1 |
| Malthe-Sorenssen, D | 1 |
| Abe, K; Anan, FK | 1 |
| Dickenson, CJ; Dickinson, FM | 2 |
| Chang, GG; Hsu, RY | 1 |
| Fan, CC; Plaut, GW; Stegeman, WJ | 1 |
| Miles, EW | 1 |
| Irie, M; Iwama, M; Ohgi, K | 1 |
| Colman, RF; Ehrlich, RS | 1 |
| Hiwatashi, A; Ichikawa, Y | 1 |
| Edwards, RG; Thomas, P; Westwood, JH | 1 |
| Leskovac, V; Pavkov-Pericin, D | 1 |
| Lhoste, JM; Mazurier, J; Montreuil, J; Spik, G | 1 |
| Berezin, IV; Egorov, AM; Popov, VO | 1 |
| Frohne, M; Hanson, H; Ludewig, M; Marquardt, I | 1 |
| Sato, S; Uchida, T | 1 |
| Raffin, JP; Remy, P | 1 |
| Collier, GE; Nishimura, JS | 1 |
| Kaback, HR; Padan, E; Patel, L | 1 |
| Little, C | 1 |
| Aldridge, WN; Bridges, JW; Elliott, BM | 1 |
| Horiike, K; McCormick, DB; Tsuge, H | 1 |
| Borders, CL; George, AL | 1 |
| Clarke, DE; Price, NC | 1 |
| Andersen, TT; Ebner, KE | 1 |
| Feeney, RE; Gold, RA; Rogers, TB | 1 |
| Dykes, CW; Kay, J | 1 |
| Halpert, J | 1 |
| McTigue, JJ; Van Etten, RL | 1 |
| Favorova, OO; Kisselev, LL; Madoyan, IA | 1 |
| Roosemont, JL | 1 |
| Boggaram, V; Mannervik, B | 1 |
| Schindler, M; Sharon, N | 1 |
| Burger, AR; Lippard, SJ; Pantoliano, MW; Ugurbil, K; Valentine, JS | 1 |
| Severin, ES; Skolysheva, LK; Vul'fson, PL | 1 |
| Aldridge, WN; Elliott, BM | 1 |
| Shepherd, MG; Soon, CY; Sullivan, PA | 1 |
| Di Cola, D; Di Ilio, C; Polidoro, G; Politi, L; Scandurra, R | 1 |
| Loosemore, MJ; Pratt, RF | 1 |
| Cooke, RD; Ferber, CE; Kanagasabapathy, L | 1 |
| Azarian, AV; Mekhanik, ML; Torchinskiĭ, IuM | 1 |
| Krysteva, MA; Mazurier, J; Montreuil, J; Spik, G | 1 |
| Landick, R; Lee, DN | 1 |
| Deyashiki, Y; Hara, A; Nakayama, T; Sawada, H; Shinoda, M | 1 |
| Biscoglio de Jiménez Bonino, M; Lacorazza, HD; Otero de Bengtsson, MS | 1 |
| Kulmacz, RJ; Tsai, AL; Zhang, X | 1 |
| Ganzhorn, AJ; Pelton, PD | 1 |
| Günzler, V; Kaska, DD; Kivirikko, KI; Myllylä, R | 1 |
| Maksay, G | 1 |
| Doran, JD; Hill, BC | 1 |
| Macek, P; Turk, T | 1 |
| McGroarty, EJ; Todt, JC | 1 |
| Chiba, S; Honma, M; Kimura, A; Matsui, H | 1 |
| Coggins, JR; Deka, RK; Kleanthous, C | 1 |
| Canut, H; Dietz, KJ; Marigo, G | 1 |
| Croteau, R; Gershenzon, J; Miyazaki, J; Rajaonarivony, JI | 1 |
| Dalton, H; Smith, DD | 1 |
| Gite, S; Reddy, G; Shankar, V | 1 |
| Schuldiner, S; Stern-Bach, Y; Suchi, R | 1 |
| Mohammadkhani, R; Said, HM | 2 |
| Berry, MJ | 1 |
| Jaffar, MB; Kumble, KD; Kumble, S | 1 |
| Galloway, DR; Kessler, SP | 1 |
| Abramson, JJ; Favero, TG; Pessah, IN; Stuart, J | 1 |
| Allakhverdiev, SI; Demeter, S; Klimov, VV | 1 |
| Kamiński, ZW; Zakrzewska, B | 1 |
| Deyashiki, Y; Hara, A; Nakayama, T; Sawada, H; Shinoda, M; Tanabe, H | 1 |
| Hersh, LB; Kim, YA; Shriver, B | 1 |
| Bandyopadhyay, U; Banerjee, RK; Bhattacharyya, DK | 2 |
| Bârzu, O; Bouhss, A; Danchin, A; Gilles, AM; Glaser, P; Krin, E; Munier, H | 1 |
| Cheon, HG; Hanna, PE | 1 |
| Bhaduri, A; Mukherji, S | 1 |
| Darnay, BG; Rodwell, VW; Wang, Y | 1 |
| Itagaki, E; Matsushita, H | 1 |
| Nimmo, HG; Robertson, AG; Rua, J | 1 |
| Ahn, HS; Foster, C; Foster, M; Sybertz, E; Wells, JN | 1 |
| Hachimori, A; Hirano, N; Ichiba, T | 1 |
| Binkley, P; Ticku, MK | 1 |
| Nierhaus, KH; Nowotny, P; Sumpter, VG; Tate, WP | 1 |
| Cescatti, L; Menestrina, G; Pederzolli, C | 2 |
| Badet, B; Badet-Denisot, MA | 1 |
| Gnatenko, DV; Korneliuk, AI; Matsuka, GKh | 1 |
| Nakatani, H; Tonomura, B; Yamashita, H | 1 |
| Caine, JM; McLeish, MJ | 1 |
| Bang, SK; Kim, YI; Kim, YS | 1 |
| Bender, H | 1 |
| Baron, DA; Halushka, PV; Hazard, ES; Mais, DE; Mayeux, PR; Morinelli, TA; Oatis, JE; Williams, TC | 1 |
| Ko, YH; McFadden, BA; Munske, GR; Vanni, P | 1 |
| Billi de Catabbi, S; Ríos de Molina, MC; San Martín de Viale, LC | 1 |
| Hunt, JV; Wolff, SP | 1 |
| Stoeva, S | 1 |
| Baboulène, M; Lattes, A; Seris, JL; Souppe, J; Urrutigoïty, M | 1 |
| Naggert, J; Smith, S; Wessa, B; Witkowski, A | 1 |
| Ichikawa, Y; Miura, S; Tomita, S | 1 |
| Inoue, Y; Ono, T | 1 |
| Paudel, HK; Yu, CA; Yu, L | 1 |
| Atkinson, T; Gore, MG; Scawen, MD; Spencer, P | 1 |
| Bonet-Kerrache, AA; Walsh, MP | 1 |
| Rubidge, T; Titball, RW | 1 |
| Bauer, PI; Buki, KG; Kun, E | 1 |
| Coan, C; DiCarlo, R | 1 |
| Dashkevich, IN; Pikulev, AT; Senchuk, VV | 1 |
| Dumas, DP; Raushel, FM | 1 |
| Drabikowska, AK; Woźniak, G | 1 |
| Dürckheimer, W; Girbig, F; Gutjahr, U; Kramer, W; Leipe, I; Oekonomopulos, R | 1 |
| Adeniran, AJ; Bednar, RA | 1 |
| Begenisich, T; Spires, S | 1 |
| Hayashi, F; Kawata, Y; Kyogoku, Y; Sakiyama, F | 1 |
| Byun, SM; Kim, DJ | 1 |
| Granier, C; Loret, EP; Mansuelle, P; Rochat, H | 1 |
| Biscoglio de Jimenez Bonino, MJ; Cascone, O; Fukushima, JG; Santomé, JA | 3 |
| Blanke, SR; Hager, LP | 1 |
| Chashchin, VL; Pikuleva, IA; Usanov, SA | 1 |
| Iankovskaia, GS; Kaziuchits, OA; Nikandrov, VN | 1 |
| Fukui, S; Kuno, S; Toraya, T | 1 |
| Chiba, T; Sato, Y; Suzuki, Y | 1 |
| Pizzo, SV; Roche, PA | 1 |
| Fu, D; Robyt, JF | 1 |
| Abouakil, N; Lombardo, D; Rogalska, E | 1 |
| Bergdoll, MS; Kokan-Moore, NP | 1 |
| Butor, C; Diaz, S; Higa, HH; Varki, A | 1 |
| Montecucco, C; Papini, E; Rappuoli, R; Sandoná, D; Schiavo, G | 1 |
| Morjana, NA; Scarborough, GA | 1 |
| Gadsby, PM; Hartshorn, RT; Moura, JJ; Sinclair-Day, JD; Sykes, AG; Thomson, AJ | 1 |
| Lin, LS; Vitt, CR; Wang, A; Yamamoto, R | 1 |
| Altman, J; Kuntz, I; Lipka, JJ; Waskell, L | 1 |
| Chatonnet, A; Masson, P | 1 |
| Cheng, KC; Nowak, T | 1 |
| Leidenberger, F; Willey, KP | 1 |
| Pathre, U; Sane, PV; Singh, AK | 1 |
| Bagert, U; Röhm, KH | 1 |
| Everett, EA; Reich, NO | 1 |
| Hori, R; Inui, K; Kato, M; Maegawa, H; Okano, T | 1 |
| Rao, NA; Vijayalakshmi, D | 1 |
| Beaumont, K; Fanestil, DD; Skowroński, R | 1 |
| Jessen, H; Jørgensen, KE; Sheikh, MI; Vorum, H | 1 |
| Konopka, K; Waskell, L | 1 |
| Kim, YS; Park, C | 1 |
| Gromet-Elhanan, Z; Khananshvili, D | 1 |
| Bidigare, RR; Choudhury, RR; Mehta, BJ; Pettigrew, DW; Sander, EG; Scheffler, JE | 1 |
| Bernard, S; di Pietro, A; Gautheron, DC; Harb, J; Meflah, K | 1 |
| Che, YW; Guerrieri, F; Papa, S; Scarfò, R; Zanotti, F | 1 |
| Gacheru, SN; Kagan, HM; Trackman, PC | 1 |
| Acebal, C; Arche, R; Martin, J; Pérez-Gil, J | 1 |
| Cook, PF; Harris, BG; Hofer, HW; Rao, GS; Wariso, BA | 1 |
| Bassilana, M; Damiano, E; Leblanc, G | 1 |
| Aronson, PS; Grillo, FG | 1 |
| Hellenga, K; Mehta, J; Spilberg, I | 1 |
| Ganapathy, V; Leibach, FH; Miyamoto, Y | 1 |
| Feldman, SR; Gonias, SL; Pizzo, SV; Roche, PA | 1 |
| Lambolez, B; Rossier, J | 1 |
| Byun, HS; Kim, YI; Kim, YS | 1 |
| Lyon, M | 1 |
| Both, V; Kéry, V; Sevcík, J; Zelinka, J | 1 |
| Branks, MJ; Masouredis, SP; Victoria, EJ | 1 |
| Carrea, G; Mazzola, G; Pasta, P | 1 |
| Neujahr, HY; Sejlitz, T | 1 |
| Basu, J; Chakrabarti, P; Ghosh, A; Kundu, M | 1 |
| Brtko, J; Knopp, J | 1 |
| Don, M; Masters, C | 1 |
| Batlle, AM; Fukuda, H; Paredes, SR | 1 |
| DeMichele, A; Kinnunen, PM; Lange, LG | 1 |
| Nakatani, H | 1 |
| Hoyt, JC; Reeves, HC; Robertson, EF | 1 |
| Das, MR; Hegde, AN | 1 |
| Huynh, QK | 1 |
| Callens, M; De Bruyne, CK; Kersters-Hilderson, H; Vangrysperre, W | 1 |
| Sokolovsky, M; van Koppen, CJ | 1 |
| Holohan, PD; Ross, CR; Sokol, PP | 1 |
| Deshpande, VV; Gaikwad, SM; More, MW; Vartak, HG | 1 |
| Khan, BM | 1 |
| Baijal, M; Sane, PV | 1 |
| Kustrzeba-Wójcicka, I; Pietkiewicz, J; Wolna, E; Wolny, M | 1 |
| Bateman, RC; Hersh, LB | 1 |
| Easterbrook-Smith, SB; McCall, MN | 1 |
| Beaumont, A; Roques, BP | 1 |
| Horák, J | 1 |
| Mishin, AA; Sukhareva, BS | 1 |
| Cole, SC; Yon, RJ | 1 |
| Abdulwajid, AW; Wu, FY | 1 |
| Awasthi, YC; Bhatnagar, A; Singh, SV | 1 |
| Foster, RJ; Kolattukudy, PE | 1 |
| Bunik, VI; Gomazkova, VS | 1 |
| Fujimoto, S; Kawamoto, N; Ohara, A; Takebayashi, M | 1 |
| Bhatnagar, A; Das, B; Srivastava, SK | 1 |
| Hatefi, Y; Hederstedt, L | 1 |
| Gibson, GG; Tamburini, PP | 1 |
| Bame, KJ; Rome, LH | 1 |
| Asano, N; Kameda, Y; Matsui, K; Takeuchi, M | 1 |
| Beppu, T; Iijima, S; Oh, MJ; Saiki, T | 1 |
| Chasteen, ND; Grady, JK; Thompson, CP | 1 |
| Biscoglio de Jimenez Bonino, MJ; Cascone, O; Fukushima, JG | 1 |
| Blank, GS; Elzinga, M; Sternlicht, H; Szasz, J; Yaffe, MB | 1 |
| Church, FC; Lundblad, RL; Noyes, CM | 1 |
| Sumpter, VG; Tate, WP; Trotman, CN | 1 |
| Hsu, RY; Vernon, CN | 1 |
| Dalziel, K; Topham, CM | 1 |
| Lin, FP; Sanny, CG; Weiner, H | 1 |
| Cook, PF; Harris, BG; Rao, JG | 1 |
| Borri Voltattorni, C; Dominici, P; Tancini, B | 1 |
| Baker, ME; Hedges, MR; Sklar, DH; Terry, LS | 1 |
| el-Gul, T; Igarashi, Y; McFadden, BA | 1 |
| Bendianishvili, MV; Kretovich, VL; Loseva, LP; Shatilov, VR | 1 |
| Bornmamm, L; Hess, B | 1 |
| Begassat, F; Bénavidès, J; Dubroeucq, MC; Guérémy, C; Le Fur, G; Phan, T; Renault, C; Tur, C; Uzan, A | 1 |
| Massey, V; Nishino, T; Williams, CH | 1 |
| Fukasawa, K; Fukasawa, KM; Harada, M; Hiraoka, BY | 1 |
| Baker, ME; Fanestil, DD | 1 |
| Kita, Y; Nitta, Y; Sakaguchi, S; Watanabe, T | 1 |
| Ivanov, KK; Kazdobina, IS; Kolesnikova, VA; Shibaeva, IV; Ugriumova, GA | 1 |
| Frangione, B; Franklin, EC; Haake, DA | 1 |
| Easterbrook-Smith, SB | 1 |
| Burch, TP; Ticku, MK | 1 |
| Ng, AY; Roy, BP | 1 |
| Garcia, ML; Kaback, HR; Padan, E; Patel, L | 1 |
| Garcia, ML; Kaback, HR; Patel, L | 1 |
| Beth, A; El-Maghrabi, MR; Murray, K; Pilkis, J; Pilkis, SJ; Venkataramu, SD; Walderhaug, M | 1 |
| Berrocal, F; Carreras, J | 1 |
| Bänziger, J; Bosshard, HR; Hasler, T; Poulos, TL | 1 |
| Burnell, JN; Hatch, MD | 1 |
| Hong, J; Hunt, AG | 1 |
| Hennecke, M; Plapp, BV | 1 |
| Ida, N; Tokushige, M | 1 |
| Dasgupta, BR; Rasmussen, S | 1 |
| De Bruyne, CK; Kersters-Hilderson, H; Lippens, M; Van Doorslaer, E | 1 |
| Kosarev, IV; Surovtsev, VI; Zav'yalov, VP | 1 |
| Hatefi, Y; Vik, SB | 2 |
| Gore, MG; Rasched, I; Sund, H | 1 |
| Zanetti, G | 1 |
| Broquet, P; Louisot, P; Serres-Guillaumond, M | 1 |
| Fenton, JW; Perret, V; Villanueva, GB | 1 |
| Appaji Rao, N; Manohar, R | 1 |
| Bindslev, N; Wright, EM | 1 |
| Hayashi, S; Nakamura, S; Suzuki, M | 1 |
| Bunik, VI; Gomazkova, VS; Severin, SE | 1 |
| Baker, ME; Terry, LS | 1 |
| Carrillo, N; Vallejos, RH | 1 |
| Docter, R; Hennemann, G; Mol, JA; Visser, TJ | 1 |
| Pilch, PF | 1 |
| Aull, JL; Daron, HH | 2 |
| Masiarz, FR; McKinley, MP; Prusiner, SB | 1 |
| Chiu, FT; McPhie, P | 1 |
| McFadden, BA; Saluja, AK | 2 |
| Fujioka, M; Gomi, T | 1 |
| Davis, DJ; Vieira, BJ | 1 |
| Fujioka, M; Ogawa, H; Okamoto, M; Takata, Y | 1 |
| Cromartie, TH; Meyer, SE | 1 |
| Mildvan, AS; Smith, GM | 1 |
| Cromartie, TH | 1 |
| Kochetov, GA | 1 |
| Lombardo, D | 1 |
| Beppu, T; Shoun, H | 1 |
| Morgan, WT | 1 |
| Dickerman, HW; Gross, SC; Kumar, SA | 1 |
| Lambiris, SK; Leadlay, PF | 1 |
| Bloxham, DP | 1 |
| Leger, D; Mazurier, J; Montreuil, J; Spik, G; Tordera, V | 1 |
| Beauregard, G; Lum, J; Roufogalis, BD | 1 |
| Busto, F; de Arriaga, D; Rúa, J; Soler, J | 1 |
| Donnelly, JL; Pallotta, BS | 1 |
| Raggi, A; Ranieri-Raggi, M; Ronca, F; Sabbatini, A | 1 |
| Furumo, NC; Helton, M; Milbrandt, J; Rardin, J; Wright, SK; Zhao, FJ | 1 |
| Balkovetz, DF; Wang, D; Warnock, DG | 1 |
| Black, PN; Zhang, Q | 1 |
| Bernardi, P; Nicolli, A; Petronilli, V | 1 |
| Barrantes, FJ; Biscoglio de Jiménez Bonino, M; Bouzat, CB; Lacorazza, HD | 1 |
| Gibbons, DL; Horowitz, PM | 1 |
| Ellis, MV; Katan, M; U, S | 1 |
| Baldwin, JE; John, P; Schofield, CJ; Thomas, P; Zhang, Z | 1 |
| Lei, Y; Liu, HW; Ploux, O | 1 |
| Dennis, DT; Huang, Y | 1 |
| Chen, H; Gollnick, P; Phillips, RS | 1 |
| Barrett, J; Crowley, P; Walker, J | 1 |
| Evans, DR; Kemling, NM; Zimmermann, BH | 1 |
| Elling, L | 1 |
| Pisoni, RL; Velilla, VQ | 1 |
| Banzon, JA; Fischer, DR; Kuo, JM; Raushel, FM; Stang, PJ | 1 |
| Askalan, R; Richardson, PJ | 1 |
| Hughes, MA; Keresztessy, Z; Kiss, L | 1 |
| Anderson, PM; Holcomb, TA; Korte, JJ | 1 |
| Decottignies, P; Gadal, P; Issakidis, E; Lemaire, M; Miginiac-Maslow, M; Schmitter, JM | 1 |
| Anderson, RC; Brown, NF; Caplan, SL; Foster, DW; McGarry, JD | 1 |
| Kosar, E; Teisinger, J; Vanĕcek, J; Vyskocil, F | 1 |
| Akiyama, D; Ito, K; Minamiura, N | 1 |
| Ash, DE; Burke, CJ; Cavalli, RC; Kawamoto, S; Soprano, DR | 1 |
| Ali, R; Shah, MA | 1 |
| Lin, WY; Wu, CH; Yang, SH | 1 |
| Davis, JP; Van Etten, RL; Zhou, MM | 1 |
| del Castillo-Olivares, A; Márquez, J; Medina, MA; Núñez de Castro, I | 1 |
| Acebal, C; Castillón, MP; de la Mata, I; Domínguez, JM; Macarrón, R | 1 |
| Hughes, PJ; Kirk, CJ; Michell, RH | 1 |
| Battaglia, E; Fournel-Gigleux, S; Magdalou, J; Ouzzine, M; Pritchard, M; Radominska, A; Siest, G | 1 |
| Camici, G; Cappugi, G; Chiarugi, P; Cirri, P; Fiaschi, T; Manao, G; Ramponi, G; Raugei, G | 1 |
| Bartell, G; Easterbrook-Smith, SB; O'Brien, RO; Roeth, PJ; Thomson, SA | 1 |
| Candidus, S; Lingens, F; van Pée, KH | 1 |
| Higuchi, T; Imamura, Y; Otagiri, M | 1 |
| McGlone, K; McIlhinney, RA; Patel, PB | 1 |
| Charles, IG; Coggins, JR; Cooper, A; Deka, R; Hawkins, AR; Kelly, SM; Moore, JD; Price, NC | 1 |
| Mizushima, S; Tokuda, H; Yamanaka, M | 1 |
| Angal, S; Freedman, RB; Smith, BJ; Williamson, RA | 1 |
| Nordén, B; Takahashi, M | 1 |
| Britsch, L; Dedio, J; Forkmann, G; Saedler, H | 1 |
| Brown, AM; De Biasi, M; Drewe, JA; Kirsch, GE | 1 |
| Everson, B; Jentoft, J; Ratnoff, OD; Ryder, J | 1 |
| Li, C; Rosenberg, RC | 1 |
| Floris, G; Medda, R; Padiglia, A; Pedersen, JZ | 1 |
| Simons, LH; van Schijndel, JW; Vollenbroek, EG; Wever, R | 1 |
| Igumnova, ND; Mevkh, AT; Miroshnikov, KA; Varfolomeev, SD | 2 |
| Hausinger, RP; Park, IS | 2 |
| Chen, H; Coles, B; Huber, R; Ketterer, B; Meyer, DJ; Reinemer, P; Xia, C | 1 |
| Chang, GG; Chiou, SH; Lee, HJ | 1 |
| Ohta, T; Taguchi, H | 1 |
| Jakobs, KH; Kaldenberg-Stasch, S; Nürnberg, B; Schultz, G; Ulibarri, I; Wieland, T | 1 |
| Bessman, MJ; Brush, GS | 1 |
| Gore, MG; Greasley, PJ; Ragan, CI; Rees-Milton, KJ | 1 |
| Fanger, BO; Hibert, MF; Hoflack, JM; Huggins, JP; Jones, CR; Trumpp-Kallmeyer, S | 1 |
| Chang, SH; Mareya, SM; Miles, BW; Post, DJ; Post, LE; Raushel, FM | 1 |
| Chang, LH; Tam, MF | 1 |
| Appleman, J; Blakley, RL; Eisenstein, E; Howell, EE; Huang, FY; Huang, TH; Nichols, R; Weaver, CD | 1 |
| Boileau, G; Crine, P; Dion, N; Le Moual, H | 1 |
| Samuel, E; Samuel, M; Villanueva, GB | 1 |
| Allende, G; Canela, EI; Casadó, V; Franco, R; Lluis, C; Mallol, J | 1 |
| Ohmiya, Y; Tsuji, FI | 1 |
| Darnay, BG; Rodwell, VW | 1 |
| Iuodka, B; Kish, L; Sabaliauskene, V | 1 |
| Antón, LC; Barrio, E; Gavilanes, F; Marqués, G; Ruiz, S; Sánchez, A; Vivanco, F | 1 |
| Li, C; Moore, DS; Rosenberg, RC | 1 |
| Baksh, S; Heilmann, C; Michalak, M; Spamer, C | 1 |
| Nic a'Bhaird, N; Ramsay, RR | 1 |
| Flügel, A; Heesemann, J; Neuberger, HR; Roggenkamp, A; Schmoll, T | 1 |
| Lim, J; Turner, AJ | 2 |
| Christendat, D; Turnbull, J | 1 |
| Rao, NA; Santha, R; Vaidyanathan, CS | 1 |
| Devreese, B; McGinnity, DF; Moura, I; Moura, JJ; Pettigrew, GW; Prazeres, S; Van Beeumen, J | 1 |
| Cooney, CL; Godavarti, R; Langer, R; Sasisekharan, R | 1 |
| Borders, CL; Chen, LH; Kenyon, GL; Vásquez, JR | 1 |
| Colman, RW; Ghazaleh, FA; Omburo, GA | 1 |
| Fothergill-Gilmore, LA; Nairn, J; Price, NC; Price, RM | 1 |
| Biscoglio de Jiménez Bonino, MJ; Daniel Lacorazza, H; Otero de Bengtsson, MS | 1 |
| Acebal, C; de la Mata, I; Iannacone, S; Pilar Castillón, M; Ramón, F | 1 |
| Mitchell, GA; Miziorko, HM; Roberts, JR | 1 |
| Moriguchi, M; Sakai, K; Tsutsumi, T; Wakayama, M; Yada, H | 1 |
| Eulitz, M; Hlavica, P; Lehnerer, M | 1 |
| Inui, KI; Mukai, M; Saito, H; Terada, T | 1 |
| Bragg, PD; Hou, C | 1 |
| Jörnvall, H; Markovic, O; Stovícková, J | 1 |
| Kopecek, J; Kopecková, P; Shen, HR; Spikes, JD | 1 |
| Hughes, DW; Thompson, PR; Wright, GD | 1 |
| Gladysheva, T; Liu, J; Rosen, BP | 1 |
| Aĭrapetian, RL; Arutiunian, AV; Mardanian, SS | 1 |
| Bird, MI; Britten, CJ | 1 |
| Bazaes, S; Cardemil, E; Goldie, H; Jabalquinto, AM; Krautwurst, H; Montecinos, L | 1 |
| Peter-Katalinić, J; Rizner, TL; Strupat, K; Zakelj-Mavric, M; Zorko, M | 1 |
| Averett, WF; Lin, B; Pritchard, DG | 1 |
| Brandsch, C; Brandsch, M; Chew, CS; Ganapathy, ME; Ganapathy, V; Leibach, FH | 1 |
| Costa, B; Giusti, L; Lucacchini, A; Martini, C | 1 |
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| Josse, D; Lockridge, O; Masson, P; Renault, F; Rochu, D; Schopfer, LM; Xie, W | 1 |
| Howe, DL; Salleh, HM; Sheflyan, GY; Son, JK; Tayeh, MA; Woodard, RW | 1 |
| Boden, V; Mrabet, N; Rangeard, MH; Vijayalakshmi, MA | 1 |
| Aizono, Y; Tsuruta, H | 1 |
| Benz, S; Jakob, I; Klink, H; Kuchenbecker, M; Kürz, LL; Lehmann-Horn, F; Rüdel, R | 1 |
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| Ataie, G; Hakimelahi, GH; Hwu, JR; Moosavi-Movahedi, AA; Saboury, AA; Tsay, SC | 1 |
| Hayashi, S; Kanda, S; Moriguchi, M; Sakai, K; Wakayama, M; Yada, H; Yatsuda, Y | 1 |
| Dzhandzhugazyan, KN; Plesner, L | 1 |
| Chen, XZ; Hediger, MA; Steel, A | 1 |
| Barber, RD; Ferry, JG; Ingram-Smith, C | 1 |
| Fukuma, K; Kagami, J; Sankawa, U; Suh, DY | 1 |
| Dweck, D; Hsiao, B; Luetje, CW | 1 |
| Burk, RF; Caprioli, RM; Hill, KE; Hondal, RJ; Ma, S | 1 |
| Kelley, PM; Kipp, BH; Njus, D | 1 |
| Kobayashi, K; Tagawa, S; Takeuchi, F; Tsubaki, M | 1 |
| Lipscomb, JD; Wallar, BJ | 1 |
| Adak, S; Bandyopadhyay, D; Bandyopadhyay, U; Banerjee, RK | 1 |
| Hicks-Berger, CA; Kirley, TL; Smith, TM; Yang, F | 1 |
| Buche, A; Ellis, G; Ramirez, JM | 1 |
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| Nagata, S; Sakahira, H; Takemura, Y | 1 |
| Ball, EH; Miller, GJ | 1 |
| Chen, CH; Chu, CL; Hsiao, YY; Lin, WJ; Pan, RL; Van, RC | 1 |
| Meves, H | 1 |
| Bollettini, M; Lupidi, G; Marmocchi, F; Rotilio, G; Venardi, G | 1 |
| Henderson, LM; Mankelow, TJ | 1 |
| Bateman, RC; Booth, RE; Misquitta, SA; Temple, JS | 1 |
| Lynch, JW; Seebungkert, B | 1 |
| Cho, EH; Cho, SW; Choi, SY; Lee, J; Lee, JE | 1 |
| Gimadutdinow, O; Korn, C; Meiss, G; Pingoud, A; Scholz, SR | 1 |
| Hirano, A; Koyama, N | 1 |
| Bhattacharjee, H; Rosen, BP | 1 |
| Ding, S; Li, Y; Zhu, L | 1 |
| Hsiao, YY; Hung, HH; Pan, RL; Van, RC | 1 |
| Aliau, S; Bonnafous, JC; Borgna, JL; Mattras, H; Richard, E | 1 |
| Antonyan, AA; Cristalli, G; Lupidi, G; Mardanyan, SS; Sharoyan, SG | 1 |
| Carvajal, N; Fuentes, M; López, V; Orellana, MS; Salas, M; Uribe, E | 1 |
| Bandyopadhyay, D; Bandyopadhyay, U; Banerjee, RK; Mazumdar, A | 1 |
| Nakamura, M; Ohno-Iwashita, Y; Sekino-Suzuki, N; Shimada, Y | 1 |
| Chakrabartty, A; Coomaraswamy, J; Fraser, PE; Goldberg, JM; Lugowski, S; Mastrangelo, P; Petromilli, C; Prusiner, SB; Qin, K; Westaway, D; Yang, Y | 1 |
| Bellomio, A; Morero, RD; Rintoul, MR | 1 |
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| Kaulpiboon, J; Pongsawasdi, P | 1 |
| Abe, Y; Hamasaki, N; Jin, XR; Li, CY | 1 |
| Misono, KS; Miyagi, M; Ogawa, H; Qiu, Y | 1 |
| Popov, VO; Savel'eva, ND; Tikhonova, TV | 1 |
| Chang, CH; Chen, YJ; Huang, CY; Ko, CY; Liao, HK; Wu, TK | 1 |
| Parker, AR | 1 |
| Habibi-Rezaei, M; Hosseini, G; Hosseinkhani, S; Moosavi-Movahedi, AA; Safarian, S; Sheibani, N; Sorenson, C; Xia, Z | 1 |
| Chen, G | 1 |
| Chen, GJ; Goodall, JJ; Page, MG | 1 |
| Ma, J; Pan, Z; You, G; Zhou, F | 1 |
| Relyea, HA; Rimkus, S; van der Donk, WA; Wheatley, JL; Woodyer, R | 1 |
| Faridmoayer, A; Scaman, CH | 1 |
| Cho, B; Karki, P; Lee, J; Park, IS; Shin, SY | 1 |
| Hashimoto, O; Higaki, K; Kato, N; Matsumoto, H; Miyake, N; Nanba, E; Paraguison, RC; Sakamoto, Y; Sasaki, T; Yamamoto, K | 1 |
| Ash, DE; Cama, E; Christianson, DW; Colleluori, DM; Compher, K; Cox, JD; Emig, FA; Han, S; Jude, K; Reczkowski, RS; Scolnick, LR; Viola, RE | 1 |
| Miziorko, HM; Runquist, JA | 1 |
| Fujisawa, Y; Kamo, N; Miyauchi, S; Nara, T; Taira, T; Tateoka, R | 1 |
| Bernauer, J; Decottignies, P; Graille, M; Graziani, S; Liebl, U; Marchand, C; Myllykallio, H; Skouloubris, S; van Tilbeurgh, H; Zhou, CZ | 1 |
| Sun, ML; Wang, M; Wang, XY; Zhao, DM | 1 |
| Hori, H; Nakanishi, N; Okamoto, H; Takeuchi, F; Tamura, A; Tsubaki, M | 1 |
| Furuichi, Y; Kimura, T; Komiyama, T; Miyamoto, M; Onozato, N; Selvakumar, D | 1 |
| Deschamps, P; Kulkarni, P; Narindrasorasak, S; Sarkar, B; She, YM | 1 |
| Alexandre, MT; Arents, JC; Hellingwerf, KJ; Kennis, JT; van Grondelle, R | 1 |
| Asaka, J; Inui, K; Katsura, T; Terada, T; Tsuda, M | 1 |
| Janiczek, O; Mandl, M; Zemanova, J | 1 |
| Banerjee, T; Deo, SK; Rahimi, Y; Shrestha, S | 1 |
| Hesp, JR; Raven, ND; Sutton, JM | 1 |
| Hnízda, A; Kodícek, M; Sanda, M; Santrůcek, J; Strohalm, M | 1 |
| Hori, H; Kiyota, K; Nakanishi, N; Park, SY; Takeuchi, F; Tsubaki, M; Uno, T | 1 |
| Ginotra, YP; Kulkarni, PP | 1 |
| Elsenheimer, KN; Hakala, K; Hunsicker-Wang, LM; Konkle, ME; Robicheaux, JC; Weintraub, ST | 1 |
| Callan, PE; Pham, C; Rosenkoetter, KE; Shearer, J | 1 |
| Kayastha, AM; Kumar, S | 1 |
| Ginotra, YP; Kulkarni, PP; Ramteke, SN; Srikanth, R | 1 |
| Das, KP; Karmakar, S | 1 |
| Ghosh, S; Ray, M; Ray, S | 1 |
| Futagi, Y; Iseki, K; Kobayashi, M; Ogura, J; Sasaki, S; Yamaguchi, H | 1 |
| Friedemann, M; Palumaa, P; Tõugu, V | 1 |
| Biehn, SE; Limpikirati, P; Lindert, S; Vachet, RW | 1 |
| Kirsch, ZJ; Pan, X; Vachet, RW | 1 |
2 review(s) available for diethyl pyrocarbonate and histidine
| Article | Year |
|---|---|
Structure of the active center of transketolase.
Topics: Apoenzymes; Arginine; Binding Sites; Calcium; Diacetyl; Diethyl Pyrocarbonate; Histidine; Magnesium; Saccharomyces cerevisiae; Structure-Activity Relationship; Thiamine Pyrophosphate; Transketolase | 1982 |
Studies of histidine residues in soybean (Glycine max) urease.
Topics: Catalytic Domain; Diethyl Pyrocarbonate; Glycine max; Histidine; Hydroxamic Acids; Kinetics; Seeds; Soybean Proteins; Urease | 2012 |
501 other study(ies) available for diethyl pyrocarbonate and histidine
| Article | Year |
|---|---|
Evidence for histidine as another functional group of delta-aminolevulinic acid dehydratase from beef liver.
Topics: Amino Acids; Animals; Binding Sites; Cattle; Diethyl Pyrocarbonate; Dithiothreitol; Histidine; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Liver; Molecular Weight; Photochemistry; Porphobilinogen Synthase; Protein Binding | 1975 |
Possible occurrence for histidyl and cysteyl residues in the catalytic center of rat liver mitochondrial D (-)-beta-hydroxybutyrate dehydrogenase.
Topics: Acetoacetates; Animals; Binding Sites; Chloromercuribenzoates; Cysteine; Dicarboxylic Acids; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxybutyrate Dehydrogenase; Kinetics; Malonates; Mitochondria, Liver; Rats; Succinates | 1975 |
An investigation of an unusual histidyl residue in Escherichia coli B L-asparaginase through fluorescence quenching.
Topics: Asparaginase; Binding Sites; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Temperature | 1976 |
Properties of crystalline reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase from bovine adrenocortical mitochondria. II. Essential histidyl and cysteinyl residues at the NADPH binding site of NADPH-adrenodoxin reductase.
Topics: Adrenal Cortex; Adrenal Glands; Adrenodoxin; Animals; Binding Sites; Cattle; Cysteine; Diethyl Pyrocarbonate; Ferredoxin-NADP Reductase; Glutathione; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Light; Methylene Blue; Mitochondria; NAD; NADH, NADPH Oxidoreductases; NADP | 1976 |
The reaction of the histidine residues of luteinizing hormone with ethoxyformyl anhydride.
Topics: Animals; Binding Sites; Cattle; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Kinetics; Luteinizing Hormone; Protein Binding; Protein Conformation; Species Specificity; Swine | 1976 |
Choline acetyltransferase--evidence for acetyl transfer by a histidine residue.
Topics: Acetylcholine; Acetyltransferases; Animals; Binding Sites; Brain; Cattle; Chloromercuribenzoates; Choline O-Acetyltransferase; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Hydrogen-Ion Concentration; Thiocyanates | 1976 |
The chemical modification of beef liver catalase. V. Ethoxyformylation of histidine and tyrosine residues of catalase with diethylpyrocarbonate.
Topics: Animals; Binding Sites; Catalase; Cattle; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Kinetics; Liver; Macromolecular Substances; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Tyrosine | 1976 |
A study of the ionic properties of the essential histidine residue of yeast alcohol dehydrogenase in complexes of the enzyme with its coenzymes and substrates.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Coenzymes; Diethyl Pyrocarbonate; Ethanol; Histidine; Hydrogen; Hydrogen-Ion Concentration; Kinetics; NAD; Oxidation-Reduction; Saccharomyces cerevisiae | 1977 |
Mechanism of pigeon liver malic enzyme modification of histidyl residues by ethoxyformic anhydride.
Topics: Animals; Binding Sites; Columbidae; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Formates; Histidine; Hydroxylamines; Light; Liver; Malate Dehydrogenase; Manganese; NADP; Pyruvates; Rose Bengal; Tartronates | 1977 |
The role of an essential histidine residue of yeast alcohol dehydrogenase.
Topics: Alcohol Oxidoreductases; Binding Sites; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Kinetics; Mathematics; NAD; Photochemistry; Protein Binding; Saccharomyces cerevisiae; Spectrometry, Fluorescence | 1975 |
Studies of a reactive histidine of dyphosphopyridine nucleotide-linked isocitrate dehydrogenase from bovine heart.
Topics: Acetates; Amino Acids; Animals; Binding Sites; Cattle; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Kinetics; Magnesium; Methylene Blue; Mitochondria, Heart; NAD; Rose Bengal | 1977 |
Modification of histidyl residues in proteins by diethylpyrocarbonate.
Topics: Buffers; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Methods; Proteins; Temperature | 1977 |
Photooxidation and carbethoxylation of a minor ribonuclease from Aspergillus saitoi.
Topics: Aspergillus; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Kinetics; Photochemistry; Ribonucleases; Tryptophan | 1977 |
Histidine in the nucleotide-binding site of NADP-linked isocitrate dehydrogenase from pig heart.
Topics: Animals; Binding Sites; Diethyl Pyrocarbonate; Histidine; Hydroxylamines; Isocitrate Dehydrogenase; Kinetics; Myocardium; NADP; Protein Binding; Swine | 1978 |
Crystalline reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase from pig adrenocortical mitochondria. Essential histidyl and cysteinyl residues of the NADPH-binding site and environment of the adrenodoxin-binding site.
Topics: Adrenal Cortex; Adrenodoxin; Animals; Binding Sites; Cattle; Cysteine; Diethyl Pyrocarbonate; Ferredoxin-NADP Reductase; Ferredoxins; Histidine; Mitochondria; NADH, NADPH Oxidoreductases; NADP; Sulfhydryl Reagents; Swine | 1978 |
Effects of chemical modification of the protein on the antigenic activity of carcinoembryonic antigen.
Topics: Animals; Antigen-Antibody Reactions; Arginine; Binding Sites; Butanones; Carcinoembryonic Antigen; Diethyl Pyrocarbonate; Epitopes; Goats; Guanidines; Histidine; Imidazoles; Protein Binding; Protein Conformation; Tetranitromethane; Tryptophan; Tyrosine | 1976 |
Evidence for a histidine and a cysteine residue in the substrate-binding site of yeast alcohol dehydrogenase.
Topics: Acetamides; Alcohol Oxidoreductases; Binding Sites; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Molecular Weight; NAD; Yeasts | 1975 |
The two metal-binding sites of human serotransferrin and lactotransferrin. Differences in histidine coordination as revealed by EPR of cupric complexes.
Topics: Binding Sites; Copper; Diethyl Pyrocarbonate; Electron Spin Resonance Spectroscopy; Histidine; Humans; Transferrin | 1977 |
[The role of histidine residues of formate dehydrogenase from Bacterium sp. 1].
Topics: Aldehyde Oxidoreductases; Bacteria; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Formates; Histidine; Kinetics; NAD | 1978 |
Photoinactivation and carbethoxylation of leucine aminopeptidase.
Topics: Alkylation; Animals; Cattle; Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lens, Crystalline; Leucyl Aminopeptidase; Light; Macromolecular Substances; Magnesium; Manganese; Protein Binding; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Tyrosine; Zinc | 1975 |
Ethoxyformylation of ribonuclease U2 form Ustilago sphaerogena.
Topics: Acylation; Adenosine Monophosphate; Basidiomycota; Chemical Phenomena; Chemistry; Chromatography; Circular Dichroism; Diethyl Pyrocarbonate; Enzyme Activation; Formates; Guanine Nucleotides; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Ribonucleases; Tyrosine; Ustilago | 1975 |
Yeast phenylalanyl-tRNA synthetase. Properties of the histidyl residues.
Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Binding Sites; Diethyl Pyrocarbonate; Histidine; Light; Phenylalanine; Phenylalanine-tRNA Ligase; RNA, Transfer; Rose Bengal; Saccharomyces cerevisiae | 1978 |
Evidence for a second histidine at the active site of succinyl-CoA synthetase from Escherichia coli.
Topics: Binding Sites; Coenzyme A Ligases; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Kinetics; Phosphorylation; Protein Binding; Spectrophotometry, Ultraviolet; Succinate-CoA Ligases | 1979 |
Effect of diethylpyrocarbonate on lactose/proton symport in Escherichia coli membrane vesicles.
Topics: Biological Transport, Active; Carrier Proteins; Diethyl Pyrocarbonate; Escherichia coli; Formates; Galactosides; Histidine; Hydrogen; Kinetics; Lactose; Protons | 1979 |
The histidine residues of phospholipase C from Bacillus cereus.
Topics: Bacillus cereus; Binding Sites; Chromatography, Affinity; Diethyl Pyrocarbonate; Histidine; Kinetics; Lysine; Phospholipases; Structure-Activity Relationship | 1977 |
Triethyltin binding to cat haemoglobin. Evidence for two chemically distinct sites and a role for both histidine and cysteine residues.
Topics: Animals; Binding Sites; Cats; Chemical Phenomena; Chemistry; Cysteine; Diethyl Pyrocarbonate; Hemoglobins; Histidine; Models, Chemical; Protein Binding; Proteins; Trialkyltin Compounds; Triethyltin Compounds | 1979 |
Evidence for an essential histidyl residue at the active site of pyridoxamine (pyridoxine)-5'-phosphate oxidase from rabbit liver.
Topics: Animals; Binding Sites; Diethyl Pyrocarbonate; Formates; Histidine; Kinetics; Liver; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Pyridoxaminephosphate Oxidase; Rabbits; Substrate Specificity | 1979 |
Chemical modification of histidyl and lysyl residues in yeast enolase.
Topics: Binding Sites; Diethyl Pyrocarbonate; Enzyme Reactivators; Histidine; Hydroxylamines; Lysine; Osmolar Concentration; Phosphopyruvate Hydratase; Pyridoxal Phosphate; Substrate Specificity; Temperature; Time Factors; Trinitrobenzenesulfonic Acid; Yeasts | 1979 |
The reaction of rabbit muscle creatine kinase with diethyl pyrocarbonate.
Topics: Adenosine Diphosphate; Animals; Binding Sites; Creatine Kinase; Diethyl Pyrocarbonate; Formates; Histidine; Kinetics; Ligands; Muscles; Rabbits | 1979 |
Reaction of the histidines of prolactin with ethoxyformic anhydride. A binding site modification.
Topics: Amino Acid Sequence; Animals; Binding Sites; Biological Assay; Cattle; Diethyl Pyrocarbonate; Female; Formates; Histidine; Humans; Mammary Glands, Animal; Placental Lactogen; Prolactin; Protein Binding; Protein Conformation; Rabbits; Receptors, Drug; Sheep; Species Specificity | 1979 |
Ethoxyformylation and photooxidation of histidines in transferrins.
Topics: Animals; Apoproteins; Binding Sites; Chickens; Conalbumin; Diethyl Pyrocarbonate; Egg Proteins; Histidine; Humans; Iron; Kinetics; Light; Oxidation-Reduction; Protein Binding; Transferrin | 1977 |
The effect of modification of lysine and histidine residues on the potential activity of pig pepsinogen [proceedings].
Topics: Animals; Binding Sites; Diethyl Pyrocarbonate; Histidine; Imides; Lysine; Pepsinogens; Swine | 1977 |
Structure and function of neuro- and myotoxic phospholipases: modification with ethoxyformic anhydride of notechis II-5 from the venom of the Australian tiger snake Notechis scutatus scutatus.
Topics: Animals; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Egg Yolk; Female; Formates; Histidine; Lysine; Neurotoxins; Phosphatidylcholines; Phospholipases; Snake Venoms; Snakes; Tyrosine | 1979 |
An essential active-site histidine residue in human prostatic acid phosphatase. Ethoxyformylation by diethyl pyrocarbonate and phosphorylation by a substrate.
Topics: Acid Phosphatase; Amino Acids; Binding Sites; Diethyl Pyrocarbonate; Formates; Histidine; Humans; Kinetics; Male; Nitrophenols; Organophosphorus Compounds; Prostate; Trinitrobenzenesulfonic Acid | 1978 |
Evidence for essential histidine residues in tryptophanyl-tRNA synthetase.
Topics: Amino Acyl-tRNA Synthetases; Animals; Binding Sites; Cattle; Circular Dichroism; Diethyl Pyrocarbonate; Histidine; Kinetics; Pancreas; RNA, Transfer; Spectrophotometry, Ultraviolet; Tryptophan-tRNA Ligase | 1978 |
Reaction of histidine residues in proteins with diethylpyrocarbonate: differential molar absorptivities and reactivities.
Topics: Diethyl Pyrocarbonate; Histidine; Kinetics; Protein Binding; Proteins; Spectrophotometry, Ultraviolet | 1978 |
An essential histidine residue in the catalytic mechanism of mammalian glutathione reductase.
Topics: Binding Sites; Diethyl Pyrocarbonate; Erythrocytes; Flavin-Adenine Dinucleotide; Glutathione Reductase; Histidine; Humans; Kinetics | 1978 |
Reversible inactivation of lactose synthase by the modification of His 32 in human alpha-lactalbumin.
Topics: Binding Sites; Diethyl Pyrocarbonate; Histidine; Humans; Kinetics; Lactalbumin; Lactose Synthase; Magnetic Resonance Spectroscopy; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet | 1976 |
Nuclear magnetic resonance and chemical modification studies of bovine erythrocyte superoxide dismutase: evidence for zinc-promoted organization of the active site structure.
Topics: Animals; Binding Sites; Cattle; Diethyl Pyrocarbonate; Erythrocytes; Histidine; Kinetics; Magnetic Resonance Spectroscopy; Protein Conformation; Superoxide Dismutase; Zinc | 1977 |
[Modification of phosphorylase b histidine residues by diethylpyrocarbonate].
Topics: Adenosine Monophosphate; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Enzyme Reactivators; Formates; Histidine; Hydroxylamines; Macromolecular Substances; Phosphorylases | 1977 |
Binding of triethyltin to cat haemoglobin and modification of the binding sites by diethyl pyrocarbonate.
Topics: Animals; Binding Sites; Binding, Competitive; Cats; Diethyl Pyrocarbonate; Formates; Hemoglobins; Histidine; Methylene Blue; Organometallic Compounds; Oxidation-Reduction; Photochemistry; Protein Binding; Trialkyltin Compounds; Triethyltin Compounds | 1977 |
Modification of lactate oxidase with diethyl pyrocarbonate. Evidence for an active-site histidine residue.
Topics: Binding, Competitive; Diethyl Pyrocarbonate; Flavin Mononucleotide; Formates; Histidine; Kinetics; Lactates; Mixed Function Oxygenases; Oxidoreductases | 1977 |
Chemical modifications of histidine residues in cytoplasmic asparate aminotransferase from beef kidney.
Topics: Animals; Apoenzymes; Aspartate Aminotransferases; Binding Sites; Cattle; Cytoplasm; Diethyl Pyrocarbonate; Fluoresceins; Histidine; Hydroxymercuribenzoates; Kidney; Kinetics; Protein Binding; Protein Conformation; Tetranitromethane | 1976 |
The irreversible cleavage of histidine residues by diethylpyrocarbonate (ethoxyformic anhydride).
Topics: Diethyl Pyrocarbonate; Formates; Histidine; Kinetics; Methods; Proteins; Spectrophotometry, Ultraviolet | 1976 |
Purification and characterisation of polygalacturonases from a commercial Aspergillus niger preparation.
Topics: Aspergillus; Aspergillus niger; Diethyl Pyrocarbonate; Glycoside Hydrolases; Histidine; Hydroxylamines; Kinetics; Macromolecular Substances; Polygalacturonase | 1976 |
[Modification of histidine residues with diethylpyrocarbonate in aspartate transaminases from pig and chicken heart cytosol].
Topics: Animals; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Chickens; Cytosol; Diethyl Pyrocarbonate; Formates; Histidine; Myocardium; Protein Denaturation; Structure-Activity Relationship; Swine | 1976 |
Comparative study on histidine modification by diethylpyrocarbonate in human serotransferrin and lactotransferrin.
Topics: Apoproteins; Binding Sites; Diethyl Pyrocarbonate; Female; Formates; Histidine; Humans; Iron; Kinetics; Milk, Human; Pregnancy; Protein Binding; Transferrin | 1975 |
Structure of RNA and DNA chains in paused transcription complexes containing Escherichia coli RNA polymerase.
Topics: Base Sequence; Diethyl Pyrocarbonate; DNA-Directed RNA Polymerases; DNA, Bacterial; Escherichia coli; Histidine; Macromolecular Substances; Molecular Sequence Data; Motion; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Nucleic Acid Hybridization; Operon; Potassium Permanganate; Ribonuclease, Pancreatic; RNA, Bacterial; Transcription, Genetic; Tryptophan | 1992 |
Modification of pig liver dimeric dihydrodiol dehydrogenase with diethylpyrocarbonate and by rose bengal-sensitized photooxidation: evidence for an active-site histidine residue.
Topics: Alcohol Oxidoreductases; Animals; Binding Sites; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Liver; Macromolecular Substances; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Photochemistry; Rose Bengal; Spectrometry, Fluorescence; Swine; Tyrosine | 1992 |
Role of histidine residues in the alpha-bungarotoxin binding site of the nicotinic acetylcholine receptor.
Topics: Animals; Binding Sites; Bungarotoxins; Carbachol; Diethyl Pyrocarbonate; Drug Residues; Electric Fish; Electrophoresis, Polyacrylamide Gel; Female; Histidine; Male; Receptors, Nicotinic | 1992 |
Chemical modification of prostaglandin H synthase with diethyl pyrocarbonate.
Topics: Acetylation; Animals; Apoenzymes; Aspirin; Cyclooxygenase Inhibitors; Diethyl Pyrocarbonate; Electron Spin Resonance Spectroscopy; Glucosides; Histidine; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Male; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Sheep; Spectrophotometry; Structure-Activity Relationship | 1992 |
The effect of histidine modification on the activity of myo-inositol monophosphatase from bovine brain.
Topics: Animals; Binding Sites; Brain; Cattle; Chromatography, High Pressure Liquid; Diethyl Pyrocarbonate; Histidine; Kinetics; Phosphoric Monoester Hydrolases; Spectrophotometry, Ultraviolet | 1992 |
Modification of vertebrate and algal prolyl 4-hydroxylases and vertebrate lysyl hydroxylase by diethyl pyrocarbonate. Evidence for histidine residues in the catalytic site of 2-oxoglutarate-coupled dioxygenases.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chick Embryo; Chlamydomonas reinhardtii; Diethyl Pyrocarbonate; DNA; Histidine; Ketoglutaric Acids; Molecular Sequence Data; Oxygenases; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; Procollagen-Proline Dioxygenase; Sequence Homology, Nucleic Acid; Spectrophotometry, Ultraviolet | 1992 |
Modification of benzodiazepine receptors supports the distinctive role of histidine residues.
Topics: Animals; Azides; Benzodiazepines; Brain; Diethyl Pyrocarbonate; Epoxy Compounds; Histidine; In Vitro Techniques; Male; Rats; Rats, Wistar; Receptors, GABA-A; Structure-Activity Relationship; Tetranitromethane; Tritium | 1992 |
Effect of diethyl pyrocarbonate modification on spectral and steady-state kinetic properties of bovine heart cytochrome oxidase.
Topics: Animals; Cattle; Diethyl Pyrocarbonate; Electron Transport; Electron Transport Complex IV; Histidine; Kinetics; Liposomes; Models, Biological; Myocardium; Oxidation-Reduction; Protons; Spectrophotometry, Ultraviolet | 1992 |
The role of lysine, histidine and carboxyl residues in biological activity of equinatoxin II, a pore forming polypeptide from the sea anemone Actinia equina L.
Topics: Animals; Cattle; Cnidarian Venoms; Diethyl Pyrocarbonate; Hemolysis; Histidine; Humans; Indicators and Reagents; Isoelectric Focusing; Lipoproteins; Lysine; Molecular Weight; Pyridoxal Phosphate; Sea Anemones; Spectrophotometry | 1992 |
Involvement of histidine-21 in the pH-induced switch in porin channel size.
Topics: Bacterial Outer Membrane Proteins; Diethyl Pyrocarbonate; Escherichia coli; Fourier Analysis; Histidine; Hydrogen-Ion Concentration; Ion Channels; Protein Structure, Secondary; Spectrophotometry, Infrared | 1992 |
Evidence for a single catalytic site of honeybee alpha-glucosidase I by chemical modification with diethylpyrocarbonate.
Topics: alpha-Glucosidases; Animals; Bees; Catalysis; Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Isoenzymes; Kinetics | 1992 |
Identification of the essential histidine residue at the active site of Escherichia coli dehydroquinase.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Hydro-Lyases; Ligands; Molecular Sequence Data; Peptide Fragments; Sequence Alignment | 1992 |
Identification of an essential histidine residue at the active site of the tonoplast malate carrier in Catharanthus roseus cells.
Topics: Biological Transport; Carrier Proteins; Cells, Cultured; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Malates; Plant Cells; Plant Physiological Phenomena; Plants; Rose Bengal; Vacuoles | 1992 |
Evidence for an essential histidine residue in 4S-limonene synthase and other terpene cyclases.
Topics: Binding Sites; Cysteine; Diethyl Pyrocarbonate; Histidine; Intramolecular Lyases; Isomerases; Kinetics; Plants; Rose Bengal | 1992 |
Evidence for two histidine ligands at the diiron site of methane monooxygenase.
Topics: Apoenzymes; Binding Sites; Circular Dichroism; Cysteine; Diethyl Pyrocarbonate; Histidine; Iron; Kinetics; Methylococcaceae; Oxygenases; Protein Structure, Secondary; Thiocyanates | 1992 |
Active-site characterization of S1 nuclease. II. Involvement of histidine in catalysis.
Topics: Aspergillus oryzae; Binding Sites; Catalysis; Circular Dichroism; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Oxidation-Reduction; Photochemistry; Single-Strand Specific DNA and RNA Endonucleases | 1992 |
Modification of arginyl or histidyl groups affects the energy coupling of the amine transporter.
Topics: Animals; Arginine; Biogenic Amines; Biological Transport; Diethyl Pyrocarbonate; Glycoproteins; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Ketanserin; Membrane Glycoproteins; Membrane Transport Proteins; Neuropeptides; Phenylglyoxal; Reserpine; Structure-Activity Relationship; Vesicular Biogenic Amine Transport Proteins | 1992 |
Involvement of histidine residues and sulfhydryl groups in the function of the biotin transport carrier of rabbit intestinal brush-border membrane.
Topics: Animals; Biological Transport; Biotin; Diethyl Pyrocarbonate; Histidine; In Vitro Techniques; Jejunum; Kinetics; Microvilli; Rabbits; Sulfhydryl Compounds; Tritium | 1992 |
Identification of essential histidine residues in rat type I iodothyronine deiodinase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Diethyl Pyrocarbonate; Histidine; Iodide Peroxidase; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; Rats; Recombinant Proteins; Rose Bengal; Transfection | 1992 |
Inactivation of a beta-glucosidase from Arthrobotrys conoides by diethyl pyrocarbonate: evidence of histidine at the active site.
Topics: beta-Glucosidase; Binding Sites; Diethyl Pyrocarbonate; Histidine; Iodoacetamide; Mitosporic Fungi; Nitrophenylgalactosides; Pyridoxal Phosphate | 1992 |
Pseudomonas aeruginosa exotoxin A interaction with eucaryotic elongation factor 2. Role of the His426 residue.
Topics: ADP Ribose Transferases; Antibodies, Monoclonal; Bacterial Toxins; Diethyl Pyrocarbonate; Exotoxins; Histidine; NAD; Peptide Elongation Factor 2; Peptide Elongation Factors; Poly(ADP-ribose) Polymerases; Protein Binding; Protein Conformation; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Structure-Activity Relationship; Virulence Factors | 1992 |
Photooxidation of skeletal muscle sarcoplasmic reticulum induces rapid calcium release.
Topics: Adenosine Triphosphatases; Animals; Calcium; Cysteine; Diethyl Pyrocarbonate; Histidine; Kinetics; Muscles; Photochemistry; Rabbits; Rose Bengal; Sarcoplasmic Reticulum | 1992 |
Thermoluminescence evidence for light-induced oxidation of tyrosine and histidine residues in manganese-depleted photosystem II particles.
Topics: 4-Chloro-7-nitrobenzofurazan; Diethyl Pyrocarbonate; Electron Transport; Histidine; Light; Light-Harvesting Protein Complexes; Luminescence; Manganese; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Tyrosine | 1992 |
Involvement of histidine residues in catalytic activity of xanthine dehydrogenase from hen liver.
Topics: 2,6-Dichloroindophenol; Animals; Chickens; Diethyl Pyrocarbonate; Enzyme Activation; Female; Histidine; Kinetics; Liver; NAD; Oxidation-Reduction; Photochemistry; Structure-Activity Relationship; Xanthine; Xanthine Dehydrogenase; Xanthines | 1992 |
Chemical modification of cysteinyl, lysyl and histidyl residues of mouse liver 17 beta-hydroxysteroid dehydrogenase.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Binding Sites; Coenzymes; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Ligands; Liver; Lysine; Mice; Protein Binding; Spectrum Analysis; Structure-Activity Relationship; Trinitrobenzenesulfonic Acid | 1992 |
Mutational analysis reveals only one catalytic histidine in neutral endopeptidase ("enkephalinase").
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; Diethyl Pyrocarbonate; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Neprilysin; Oligodeoxyribonucleotides; Rats; Recombinant Proteins; Substrate Specificity; Transfection | 1992 |
Chemical and kinetic evidence for an essential histidine in horseradish peroxidase for iodide oxidation.
Topics: Diethyl Pyrocarbonate; Histidine; Horseradish Peroxidase; Iodides; Kinetics; Oxidation-Reduction; Spectrophotometry, Ultraviolet | 1992 |
The role of histidine 63 in the catalytic mechanism of Bordetella pertussis adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Base Sequence; Bordetella pertussis; Cloning, Molecular; Codon; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Recombinant Proteins | 1992 |
Effect of group-selective modification reagents on arylamine N-acetyltransferase activities.
Topics: Animals; Arginine; Arylamine N-Acetyltransferase; Binding Sites; Cricetinae; Cysteine; Diethyl Pyrocarbonate; Enzyme Activation; Ethylmaleimide; Histidine; Hydroxylamine; Hydroxylamines; Liver; Male; Mesocricetus; Phenylglyoxal | 1992 |
An essential histidine residue for the activity of UDPglucose 4-epimerase from Kluyveromyces fragilis.
Topics: Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Kinetics; Kluyveromyces; NAD; Oxidation-Reduction; Spectrometry, Fluorescence; UDPglucose 4-Epimerase | 1992 |
Identification of the catalytically important histidine of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Topics: Amino Acid Sequence; Base Sequence; Catalysis; Chromatography, DEAE-Cellulose; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides; Pseudomonas; Substrate Specificity | 1992 |
Essential histidine residue in 3-ketosteroid-delta 1-dehydrogenase.
Topics: Binding Sites; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Kinetics; Nocardia; Oxidoreductases; Photochemistry | 1992 |
Identification of the histidine residue in Escherichia coli isocitrate lyase that reacts with diethylpyrocarbonate.
Topics: Amino Acid Sequence; Binding Sites; Diethyl Pyrocarbonate; Enzyme Reactivators; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Isocitrate Lyase; Isocitrates; Kinetics; Molecular Sequence Data; Peptide Fragments; Sulfhydryl Compounds; Trypsin | 1992 |
Evidence for essential histidine and cysteine residues in calcium/calmodulin-sensitive cyclic nucleotide phosphodiesterase.
Topics: Animals; Brain; Catalysis; Cattle; Cyclic Nucleotide Phosphodiesterases, Type 1; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Enzyme Activation; Ethylmaleimide; Histidine; Hydrogen-Ion Concentration; Kinetics; Phosphoric Diester Hydrolases; Spectrophotometry, Ultraviolet | 1991 |
The role of histidine-118 of inorganic pyrophosphatase from thermophilic bacterium PS-3.
Topics: Amino Acids; Binding Sites; Chromatography, High Pressure Liquid; Diethyl Pyrocarbonate; Histidine; Kinetics; Magnesium; Pyrophosphatases; Thermus | 1991 |
Histidine residue is crucial for the binding of ligands to the benzodiazepine site except Ro15-4513.
Topics: Animals; Azides; Benzodiazepines; Binding Sites; Cerebellum; Cerebral Cortex; Diethyl Pyrocarbonate; Flunitrazepam; Histidine; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
Modification of histidine residues on proteins from the 50S subunit of the Escherichia coli ribosome. Effects on subunit assembly and peptidyl transferase centre activity.
Topics: Centrifugation, Density Gradient; Diethyl Pyrocarbonate; Electrophoresis, Gel, Two-Dimensional; Escherichia coli; Histidine; Peptidyl Transferases; Ribosomal Proteins; RNA, Bacterial; RNA, Ribosomal; Structure-Activity Relationship | 1991 |
Modification of lysine residues of Staphylococcus aureus alpha-toxin: effects on its channel-forming properties.
Topics: Bacterial Toxins; Diethyl Pyrocarbonate; Electrochemistry; Electrophoresis, Polyacrylamide Gel; Hemolysin Proteins; Histidine; Hydroxylamine; Hydroxylamines; Ion Channels; Isoelectric Focusing; Lipid Bilayers; Lysine; Staphylococcus aureus; Trinitrobenzenesulfonic Acid | 1991 |
Chemical modification of glucosamine-6-phosphate synthase by diethyl pyrocarbonate: evidence of histidine requirement for enzymatic activity.
Topics: Binding Sites; Diethyl Pyrocarbonate; Escherichia coli; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Histidine; Kinetics; Protein Binding; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1992 |
[Tyrosyl-tRNA-synthetase from bovine liver. Functional role of histidine residues].
Topics: Adenosine Triphosphate; Animals; Catalysis; Cattle; Diethyl Pyrocarbonate; Histidine; Kinetics; Spectrum Analysis; Substrate Specificity; Tyrosine-tRNA Ligase | 1991 |
Substrate-selective activation of histidine-modified porcine pancreatic alpha-amylase by chloride ion.
Topics: alpha-Amylases; Animals; Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Isoenzymes; Kinetics; Pancreas; Substrate Specificity; Swine | 1991 |
Chemical modification of PABA synthase.
Topics: Arginine; Cysteine; Diethyl Pyrocarbonate; Escherichia coli; Folic Acid; Histidine; Iodoacetamide; Phenylglyoxal; Sulfhydryl Reagents; Tetranitromethane; Transaminases; Tyrosine | 1991 |
Chemical modification of Pseudomonas fluorescens malonyl-CoA synthetase by diethylpyrocarbonate: kinetic evidence for an essential histidyl residue on alpha subunit.
Topics: Adenosine Triphosphate; Bacterial Proteins; Binding Sites; Coenzyme A; Coenzyme A Ligases; Diethyl Pyrocarbonate; Enzyme Reactivators; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Macromolecular Substances; Malonates; Pseudomonas fluorescens | 1991 |
On the role of histidine residues in cyclodextrin glycosyltransferase: chemical modification with diethyl pyrocarbonate.
Topics: Amino Acid Sequence; Bacillus; Binding Sites; Diethyl Pyrocarbonate; Glucosyltransferases; Histidine; Klebsiella pneumoniae; Molecular Sequence Data | 1991 |
Differential effect of pH on thromboxane A2/prostaglandin H2 receptor agonist and antagonist binding in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bromosuccinimide; Carbazoles; Cell Membrane; Diethyl Pyrocarbonate; Fatty Acids, Unsaturated; Histidine; Humans; Hydrazines; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Ligands; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Protein Binding; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Solubility; Thromboxane A2 | 1991 |
Substrate-decreased modification by diethyl pyrocarbonate of two histidines in isocitrate lyase from Escherichia coli.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Diethyl Pyrocarbonate; Diethylamines; Escherichia coli; Glyoxylates; Histidine; Hydrogen-Ion Concentration; Isocitrate Lyase; Isocitrates; Kinetics; Macromolecular Substances; Molecular Sequence Data; Spectrophotometry, Ultraviolet; Succinates; Succinic Acid | 1991 |
Studies on the active centre of rat liver porphyrinogen carboxylase in vivo effect of hexachlorobenzene.
Topics: Animals; Arginine; Binding Sites; Carboxy-Lyases; Diethyl Pyrocarbonate; Epoxy Compounds; Female; Hexachlorobenzene; Histidine; Hydroxylamine; Hydroxylamines; Liver; Methylene Blue; Photochemistry; Porphyrias; Rats; Rats, Inbred Strains; Spectrophotometry; Uroporphyrinogens | 1991 |
The role of histidine residues in the nonenzymic covalent attachment of glucose and ascorbic acid to protein.
Topics: Animals; Ascorbic Acid; Binding Sites; Cattle; Copper; Diethyl Pyrocarbonate; Dogs; Glucose; Glycosylation; Histidine; Oxidation-Reduction; Serum Albumin; Serum Albumin, Bovine | 1991 |
Modification of a zinc proteinase from Bacillus mesentericus strain 76 by diethylpyrocarbonate.
Topics: Amino Acid Sequence; Bacillus; Binding, Competitive; Chymotrypsin; Diethyl Pyrocarbonate; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Metalloendopeptidases; Molecular Sequence Data; Phenylalanine | 1991 |
Effect of linking allyl and aromatic chains to histidine 170 in horseradish peroxidase.
Topics: Acetophenones; Allyl Compounds; Binding Sites; Diethyl Pyrocarbonate; Heme; Histidine; Horseradish Peroxidase; Kinetics; Peptides; Trypsin | 1991 |
A catalytic role for histidine 237 in rat mammary gland thioesterase II.
Topics: Animals; Base Sequence; Binding Sites; Catalysis; Diethyl Pyrocarbonate; DNA; Fatty Acid Synthases; Histidine; Hydrogen-Ion Concentration; Kinetics; Mammary Glands, Animal; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylmethylsulfonyl Fluoride; Rats; Substrate Specificity; Thiolester Hydrolases | 1991 |
Modification of histidine 56 in adrenodoxin with diethyl pyrocarbonate inhibited the interaction with cytochrome P-450scc and adrenodoxin reductase.
Topics: Adrenodoxin; Animals; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Diethyl Pyrocarbonate; Ferredoxin-NADP Reductase; Histidine; Magnetic Resonance Spectroscopy; NADH Dehydrogenase; Oxidation-Reduction; Substrate Specificity | 1991 |
Biochemical evidence for histidine oxidation in photosystem II depleted of the Mn-cluster for O2-evolution.
Topics: Diethyl Pyrocarbonate; Histidine; In Vitro Techniques; Manganese; Metalloproteins; Oxidation-Reduction; Oxygen; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Plants | 1991 |
Involvement of a histidine residue in the interaction between membrane-anchoring protein (QPs) and succinate dehydrogenase in mitochondrial succinate-ubiquinone reductase.
Topics: Diethyl Pyrocarbonate; Electron Transport Complex II; Histidine; Kinetics; Macromolecular Substances; Mitochondria; Multienzyme Complexes; Oxidoreductases; Spectrophotometry; Succinate Dehydrogenase | 1991 |
Chemical modification of Staphylococcus aureus alpha-toxin by diethylpyrocarbonate: role of histidines in its membrane-damaging properties.
Topics: Animals; Bacterial Toxins; Blood Coagulation Tests; Blood Platelets; Cattle; Diethyl Pyrocarbonate; Erythrocyte Membrane; Hemolysin Proteins; Histidine; Humans; Kinetics; Lipid Bilayers; Rabbits; Staphylococcus aureus; Structure-Activity Relationship; Swine | 1991 |
The identification of a structurally important cysteine residue in the glycerol dehydrogenase from Bacillus stearothermophilus.
Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cobalt; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Geobacillus stearothermophilus; Histidine; Iodoacetates; Iodoacetic Acid; Kinetics; Macromolecular Substances; Methyl Methanesulfonate; Molecular Weight; Peptide Fragments; Sugar Alcohol Dehydrogenases; Tritium; Trypsin; Zinc | 1991 |
Chemical modification of the sole histidine residue of smooth muscle caldesmon.
Topics: Adenosine Triphosphate; Animals; Brain; Calmodulin; Calmodulin-Binding Proteins; Cattle; Chickens; Diethyl Pyrocarbonate; Gizzard, Avian; Histidine; Kinetics; Muscle, Smooth | 1991 |
The role of histidine residues in the alpha toxin of Clostridium perfringens.
Topics: Amino Acid Sequence; Bacterial Toxins; Calcium-Binding Proteins; Clostridium perfringens; Diethyl Pyrocarbonate; Edetic Acid; Histidine; Hydroxylamines; Molecular Sequence Data; Sequence Homology, Nucleic Acid; Type C Phospholipases; Zinc | 1990 |
Evidence for the participation of histidine residues located in the 56 kDa C-terminal polypeptide domain of ADP-ribosyl transferase in its catalytic activity.
Topics: Binding Sites; Cellulose; Diethyl Pyrocarbonate; DNA; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Light; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Binding; Rose Bengal | 1990 |
Effect of diethyl pyrocarbonate modification on the calcium binding mechanism of the sarcoplasmic reticulum ATPase.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Binding Sites; Calcium; Chromatography, Gel; Diethyl Pyrocarbonate; Formates; Histidine; Kinetics; Muscles; Phosphorylation; Rabbits; Sarcoplasmic Reticulum | 1990 |
[Study of the modification of histidine residues, SH- and epsilon-NH2-groups of rat sarcoma-45 myosin by specific reagents].
Topics: Amines; Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Chloromercuribenzoates; Diethyl Pyrocarbonate; Histidine; Myosins; Neoplasm Proteins; p-Chloromercuribenzoic Acid; Rats; Sarcoma, Experimental; Sulfhydryl Reagents; Trinitrobenzenesulfonic Acid | 1990 |
Chemical and kinetic evidence for an essential histidine in the phosphotriesterase from Pseudomonas diminuta.
Topics: Aryldialkylphosphatase; Binding Sites; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Kinetics; Paraoxon; Phosphoric Monoester Hydrolases; Pseudomonas; Thermodynamics | 1990 |
Modification of uridine phosphorylase from Escherichia coli by diethyl pyrocarbonate. Evidence for a histidine residue in the active site of the enzyme.
Topics: Binding Sites; Diethyl Pyrocarbonate; Escherichia coli; Formates; Histidine; Hydrogen-Ion Concentration; Kinetics; Pentosyltransferases; Uridine; Uridine Phosphorylase | 1990 |
Influence of amino acid side-chain modification on the uptake system for beta-lactam antibiotics and dipeptides from rabbit small intestine.
Topics: Affinity Labels; Alanine; Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Diethyl Pyrocarbonate; Dipeptides; Glucose; Histidine; Intestine, Small; Microvilli; Rabbits; Structure-Activity Relationship; Tyrosine | 1990 |
Chemical modification of chalcone isomerase by diethyl pyrocarbonate: histidine residues are not essential for catalysis.
Topics: Binding Sites; Catalysis; Diethyl Pyrocarbonate; Glycine max; Histidine; Intramolecular Lyases; Isomerases; Kinetics | 1990 |
Modification of potassium channel kinetics by histidine-specific reagents.
Topics: Animals; Axons; Decapodiformes; Diethyl Pyrocarbonate; Histidine; Indicators and Reagents; Kinetics; Membrane Potentials; Models, Biological; Potassium Channels; Protein Conformation | 1990 |
Identification of two essential histidine residues of ribonuclease T2 from Aspergillus oryzae.
Topics: Amino Acid Sequence; Amino Acids; Aspergillus; Aspergillus oryzae; Binding Sites; Diethyl Pyrocarbonate; Endoribonucleases; Histidine; Hydrogen-Ion Concentration; Iodoacetates; Iodoacetic Acid; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Mapping | 1990 |
Evidence for involvement of 2 histidine residues in the reaction of ampicillin acylase.
Topics: Amidohydrolases; Bromosuccinimide; Diethyl Pyrocarbonate; Histidine; Penicillin Amidase; Pseudomonas; Structure-Activity Relationship | 1990 |
Neurotoxins active on insects: amino acid sequences, chemical modifications, and secondary structure estimation by circular dichroism of toxins from the scorpion Androctonus australis Hector.
Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Circular Dichroism; Diethyl Pyrocarbonate; Histidine; Molecular Sequence Data; Neuropeptides; Protein Conformation; Scorpion Venoms; Sequence Homology, Nucleic Acid | 1990 |
Role of histidine residues in the binding mechanism of the growth hormone family.
Topics: Animals; Binding Sites; Diethyl Pyrocarbonate; Growth Hormone; Histidine; Humans; Kinetics; Liver; Molecular Conformation; Rats | 1990 |
Chemical modification of chloroperoxidase with diethylpyrocarbonate. Evidence for the presence of an essential histidine residue.
Topics: Amino Acid Sequence; Binding Sites; Chemical Phenomena; Chemistry; Chloride Peroxidase; Diethyl Pyrocarbonate; Formates; Fungi; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Models, Molecular; Molecular Sequence Data; Peroxidases; Protein Conformation; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1990 |
[Chemical modification of cholesterol-hydroxylating cytochrome P-450 from adrenal cortex mitochondria with diethylpyrocarbonate].
Topics: Adrenal Cortex; Adrenodoxin; Animals; Cholesterol Side-Chain Cleavage Enzyme; Diethyl Pyrocarbonate; Formates; Histidine; In Vitro Techniques; Kinetics; Mitochondria; Oxidation-Reduction | 1990 |
[Study of the role of histidine residues in streptokinase molecule using modification with diethylpyrocarbonate].
Topics: Chemical Phenomena; Chemistry; Chromatography, Gel; Circular Dichroism; Diethyl Pyrocarbonate; Formates; Histidine; Indicators and Reagents; Kinetics; Protein Conformation; Protein Denaturation; Streptokinase | 1990 |
Essential histidine residues in coenzyme B12-dependent diol dehydrase: dye-sensitized photooxidation and ethoxycarbonylation.
Topics: Amino Acids; Apoenzymes; Cobamides; Diethyl Pyrocarbonate; Formates; Histidine; Hydro-Lyases; Hydrogen-Ion Concentration; Kinetics; Klebsiella pneumoniae; Light; Macromolecular Substances; Methylene Blue; Oxidation-Reduction; Photochemistry; Propanediol Dehydratase; Protein Binding; Rose Bengal; Spectrophotometry | 1990 |
Amino acid residues complexed with eosin 5-isothiocyanate in band 3 protein of the human erythrocyte.
Topics: Anion Exchange Protein 1, Erythrocyte; Arginine; Binding Sites; Biological Transport; Circular Dichroism; Diethyl Pyrocarbonate; Eosine Yellowish-(YS); Erythrocyte Membrane; Histidine; Humans; Hydrogen-Ion Concentration; Ion Channels; Liposomes; Protein Conformation; Spectrum Analysis | 1986 |
The role of histidyl residues in zinc-induced precipitation of alpha 2-macroglobulin-proteinase complexes.
Topics: Acylation; alpha-Macroglobulins; Chemical Precipitation; Diethyl Pyrocarbonate; Endopeptidases; Histidine; Histones; Protein Binding; Spectrum Analysis; Zinc | 1987 |
Essential histidine residues in dextransucrase: chemical modification by diethyl pyrocarbonate and dye photo-oxidation.
Topics: Carbohydrates; Dextrans; Diethyl Pyrocarbonate; Formates; Glucosyltransferases; Histidine; Methylene Blue; Oxidation-Reduction; Proteins; Rose Bengal | 1988 |
Human milk bile-salt stimulated lipase: further investigations on the amino-acids residues involved in the catalytic site.
Topics: Acylation; Adsorption; Bile Acids and Salts; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Chemistry, Physical; Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen Bonding; Isoflurophate; Isoxazoles; Kinetics; Lipase; Micelles; Milk, Human; Phosphorylation; Serine; Spectrophotometry; Structure-Activity Relationship | 1989 |
Effect of chemical modification of histidine and tyrosine residues in toxic shock syndrome toxin 1 on the serologic and mitogenic activities of the toxin.
Topics: Animals; Antigen-Antibody Reactions; Bacterial Toxins; Diethyl Pyrocarbonate; Enterotoxins; Histidine; Immunodiffusion; Lymphocyte Activation; Mice; Mitogens; Protein Conformation; Staphylococcus aureus; Superantigens; Tyrosine | 1989 |
O-acetylation and de-O-acetylation of sialic acids. O-acetylation of sialic acids in the rat liver Golgi apparatus involves an acetyl intermediate and essential histidine and lysine residues--a transmembrane reaction?
Topics: Acetates; Acetyl Coenzyme A; Acetylation; Animals; Chromatography, High Pressure Liquid; Coenzyme A; Cytidine Monophosphate N-Acetylneuraminic Acid; Diethyl Pyrocarbonate; Golgi Apparatus; Histidine; Intracellular Membranes; Kinetics; Liver; Lysine; Lysosomes; Models, Biological; Rats; Sialic Acids | 1989 |
Histidine 21 is at the NAD+ binding site of diphtheria toxin.
Topics: Adenine; Adenosine; Binding Sites; Diethyl Pyrocarbonate; Diphtheria Toxin; Formates; Histidine; Kinetics; NAD; Niacinamide; Peptide Fragments | 1989 |
Evidence for an essential histidine residue in the Neurospora crassa plasma membrane H+-ATPase.
Topics: Binding Sites; Catalysis; Cell Membrane; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Neurospora; Neurospora crassa; Proton-Translocating ATPases; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1989 |
Redox properties of the diheme cytochrome c4 from Azotobacter vinelandii and characterisation of the two hemes by NMR, MCD and EPR spectroscopy.
Topics: Azotobacter; Cytochrome c Group; Diethyl Pyrocarbonate; Electron Spin Resonance Spectroscopy; Heme; Histidine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Methionine; Oxidation-Reduction; Spectrophotometry; Spectrum Analysis | 1989 |
Histidine-15: an important role in the cytotoxic activity of human tumor necrosis factor.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Binding, Competitive; Cell Line; Cloning, Molecular; Diethyl Pyrocarbonate; DNA; Histidine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 1989 |
Identification by proton nuclear magnetic resonance of the histidines in cytochrome b5 modified by diethyl pyrocarbonate.
Topics: Animals; Cattle; Cytochromes b5; Diethyl Pyrocarbonate; Formates; Histidine; Magnetic Resonance Spectroscopy; Molecular Structure; Protons; Rabbits; Solvents | 1989 |
Study of the peptidasic site of cholinesterase: preliminary results.
Topics: Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Diethyl Pyrocarbonate; Histidine; Humans; Isoflurophate; Neuraminidase; Organophosphorus Compounds; Peptide Hydrolases; Quinolines; Serine; Soman; Substance P; Tosyllysine Chloromethyl Ketone | 1985 |
A histidine residue at the active site of avian liver phosphoenolpyruvate carboxykinase.
Topics: Animals; Chickens; Circular Dichroism; Diethyl Pyrocarbonate; Formates; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Manganese; Mitochondria, Liver; Phosphoenolpyruvate Carboxykinase (GTP); Protein Binding; Protein Conformation | 1989 |
Functionally distinct agonist and receptor-binding regions in human chorionic gonadotropin. Development of a tertiary structure model.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Cell Membrane; Chorionic Gonadotropin; Chymotrypsin; Corpus Luteum; Diethyl Pyrocarbonate; Disulfides; Female; Histidine; Humans; Kinetics; Leydig Cells; Male; Models, Molecular; Molecular Sequence Data; Plasminogen; Protein Conformation; Rats; Receptors, Gonadotropin; Sequence Homology, Nucleic Acid; Steroids | 1989 |
Inactivation of leucine aminotransferase with diethylpyrocarbonate and rose bengal: evidence for an active site histidine residue.
Topics: Binding Sites; Diethyl Pyrocarbonate; Histidine; Indicators and Reagents; Leucine Transaminase; Plants; Rose Bengal; Transaminases | 1989 |
On the role of histidine and tyrosine residues in E. coli asparaginase. Chemical modification and 1H-nuclear magnetic resonance studies.
Topics: Asparaginase; Aspartic Acid; Bromosuccinimide; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Magnetic Resonance Spectroscopy; Spectrophotometry; Tetrazoles; Tyrosine | 1989 |
Ecori DNA methylase activity is eliminated upon histidine residue modification.
Topics: Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Histidine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 1989 |
Effect of various chemical modifiers on H+ coupled transport of cephradine via dipeptide carriers in rabbit intestinal brush-border membranes: role of histidine residues.
Topics: Animals; Biological Transport; Cephalosporins; Cephradine; Diethyl Pyrocarbonate; Dipeptides; Dithiothreitol; Dose-Response Relationship, Drug; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Intestinal Mucosa; Male; Microvilli; Rabbits | 1989 |
Identification of amino acid residues at the active site of human liver serine hydroxymethyltransferase.
Topics: Amino Acids; Arginine; Binding Sites; Bromosuccinimide; Diethyl Pyrocarbonate; Glycine Hydroxymethyltransferase; Histidine; Humans; Hydroxylamine; Hydroxylamines; Liver; Phenylglyoxal; Transferases; Tryptophan | 1989 |
Modification of the peripheral-type benzodiazepine receptor by arachidonate, diethylpyrocarbonate and thiol reagents.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzodiazepinones; Binding, Competitive; Convulsants; Diethyl Pyrocarbonate; Formates; Histidine; In Vitro Techniques; Kidney Cortex; Male; Mitochondria; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sulfhydryl Reagents | 1987 |
Mechanism of transport of L-alanine by luminal-membrane vesicles from pars recta of rabbit proximal tubule.
Topics: Alanine; Animals; Binding Sites; Biological Transport; Cell Membrane; Diethyl Pyrocarbonate; Glucose; Histidine; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Kinetics; Lactates; Lactic Acid; Potassium; Protons; Rabbits; Sodium | 1988 |
Chemical modification of cytochrome b5, cytochrome c and myoglobin with diethylpyrocarbonate.
Topics: Animals; Cytochrome b Group; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Diethyl Pyrocarbonate; Formates; Heme; Histidine; Kinetics; Male; Microsomes, Liver; Myoglobin; NADPH-Ferrihemoprotein Reductase; Rabbits | 1988 |
Inactivation of Acinetobacter calcoaceticus acetate kinase by diethylpyrocarbonate.
Topics: 4-Chloromercuribenzenesulfonate; Acetate Kinase; Acinetobacter; Binding Sites; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Ethylmaleimide; Formates; Histidine; Hydrogen-Ion Concentration; Kinetics; Phenylglyoxal; Phosphotransferases | 1988 |
Evidence that the Mg-dependent low-affinity binding site for ATP and Pi demonstrated on the isolated beta subunit of the F0.F1 ATP synthase is a catalytic site.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding Sites; Dicyclohexylcarbodiimide; Diethyl Pyrocarbonate; Histidine; Isoxazoles; Magnesium; Phosphates; Phosphorylation; Proton-Translocating ATPases; Rhodospirillum; Tyrosine | 1985 |
Enzyme elements involved in the interconversion of L-carbamylaspartate and L-dihydroorotate by dihydroorotase from Clostridium oroticum.
Topics: Amidohydrolases; Aspartic Acid; Catalysis; Clostridium; Cobalt; Cyclization; Diethyl Pyrocarbonate; Dihydroorotase; Histidine; Hydrogen-Ion Concentration; Kinetics; Orotic Acid; Zinc | 1985 |
Chemical modification of essential carboxyl group and histidine residue in the plasma-membrane 5'-nucleotidase.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adrenergic alpha-Antagonists; Animals; Cations, Divalent; Cattle; Cell Membrane; Diethyl Pyrocarbonate; Formates; Histidine; Kinetics; Liver; Nucleotidases; Quinolines | 1986 |
Inactivation of the mitochondrial ATPase inhibitor protein by chemical modification with diethylpyrocarbonate.
Topics: Animals; ATPase Inhibitory Protein; Cattle; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Edetic Acid; Histidine; Mitochondria, Heart; Proteins; Proton-Translocating ATPases; Protons; Spectrophotometry; Submitochondrial Particles | 1987 |
Evidence for a functional role for histidine in lysyl oxidase catalysis.
Topics: Algorithms; Amines; Amino Acid Oxidoreductases; Animals; Cattle; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Kinetics; Protein-Lysine 6-Oxidase; Time Factors | 1988 |
Essential histidine residues in lysolecithin:lysolecithin acetyltransferase from rabbit lung.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acyltransferases; Animals; Diethyl Pyrocarbonate; Histidine; Kinetics; Lung; Rabbits; Spectrophotometry, Ultraviolet | 1989 |
Reaction of Ascaris suum phosphofructokinase with diethylpyrocarbonate. Inactivation and desensitization to allosteric modulation.
Topics: Allosteric Regulation; Allosteric Site; Animals; Ascaris; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Phosphofructokinase-1 | 1987 |
Chemical modifications of the Na+-H+ antiport in Escherichia coli membrane vesicles.
Topics: Carboxylic Acids; Carrier Proteins; Cell Membrane; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Mathematics; Models, Chemical; Sodium-Hydrogen Exchangers; Sulfhydryl Compounds; Sulfhydryl Reagents | 1985 |
Inactivation of the renal microvillus membrane Na+-H+ exchanger by histidine-specific reagents.
Topics: Animals; Carrier Proteins; Diethyl Pyrocarbonate; Dogs; Histidine; Hydroxylamine; Hydroxylamines; Kidney Cortex; Kinetics; Microvilli; Photochemistry; Rabbits; Rose Bengal; Sodium; Sodium-Hydrogen Exchangers; Time Factors | 1986 |
Chemical modification of human neutrophil membrane proteins: effect on fMet-Leu-Phe binding and function.
Topics: Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Imidazoles; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Binding; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides | 1986 |
Identification of histidyl and thiol groups at the active site of rabbit renal dipeptide transporter.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Binding Sites; Biological Transport; Carrier Proteins; Diethyl Pyrocarbonate; Dipeptides; Dose-Response Relationship, Drug; Ethylmaleimide; Histidine; In Vitro Techniques; Kidney; Kinetics; Leucine; Protons; Rabbits; Sulfhydryl Compounds | 1986 |
Further characterization of the platinum-reactive component of the alpha 2-macroglobulin-receptor recognition site.
Topics: Amino Acids; Animals; Binding Sites; Cisplatin; Diethyl Pyrocarbonate; Ditiocarb; Histidine; Hydrogen Peroxide; In Vitro Techniques; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Methylamines; Mice; Receptors, Immunologic | 1986 |
Benzodiazepine agonists protect a histidine residue from modification by diethyl pyrocarbonate whereas propyl beta-carboline does not.
Topics: Animals; Carbolines; Cell Membrane; Cerebral Cortex; Diethyl Pyrocarbonate; Flumazenil; Formates; Histidine; Hydrogen-Ion Concentration; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Inactivation of Saccharomyces cerevisiae glucose-6-phosphate dehydrogenase by diethylpyrocarbonate.
Topics: Catalysis; Diethyl Pyrocarbonate; Formates; Glucosephosphate Dehydrogenase; Histidine; Saccharomyces cerevisiae | 1988 |
Specific chemical modifications of link protein and their effect on binding to hyaluronate and cartilage proteoglycan.
Topics: Acetylation; Animals; Arginine; Cartilage, Articular; Cattle; Chromatography, Gel; Diethyl Pyrocarbonate; Extracellular Matrix Proteins; Female; Histidine; Hyaluronic Acid; Imidazoles; Lysine; Male; Methylation; Proteins; Proteoglycans; Tryptophan; Tyrosine | 1986 |
The number and role of histidine residues in the active site of guanyloribonuclease Sa.
Topics: Binding Sites; Binding, Competitive; Circular Dichroism; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Endoribonucleases; Histidine; Ribonuclease T1; Streptomyces aureofaciens; Structure-Activity Relationship; Time Factors | 1986 |
Rh antigen immunoreactivity after histidine modification.
Topics: Diethyl Pyrocarbonate; Erythrocyte Membrane; Histidine; Humans; Hydroxylamine; Hydroxylamines; Isoantigens; Oxidation-Reduction; Rh-Hr Blood-Group System; Rose Bengal | 1986 |
Chemical modification of 3 alpha,20 beta-hydroxysteroid dehydrogenase with diethyl pyrocarbonate. Evidence for an essential, highly reactive, lysyl residue.
Topics: Binding Sites; Binding, Competitive; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Hydroxysteroid Dehydrogenases; Lysine; NAD; Progesterone; Protein Conformation; Streptomyces | 1987 |
Chemical modification of phenol hydroxylase by ethoxyformic anhydride.
Topics: Diethyl Pyrocarbonate; Formates; Histidine; Kinetics; Lysine; Mathematics; Mixed Function Oxygenases; Pyridoxal Phosphate; Saccharomyces cerevisiae; Spectrophotometry | 1987 |
Chemical modification studies on a lectin from Saccharomyces cerevisiae (baker's yeast).
Topics: Amino Acids; Arginine; Binding Sites; Carbohydrates; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Histidine; Immunodiffusion; Lectins; Saccharomyces cerevisiae; Structure-Activity Relationship; Succinic Anhydrides; Sulfhydryl Compounds | 1987 |
Study of the role of histidyl, tyrosyl, alpha- or epsilon-amino residues in the specific binding of 3,5,3'-triiodothyronine to rat liver nuclear receptors.
Topics: Amino Acids; Animals; Arginine; Cell Nucleus; Diethyl Pyrocarbonate; Histidine; Liver; Lysine; Male; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, Thyroid Hormone; Triiodothyronine, Reverse; Trinitrobenzenesulfonic Acid; Tyrosine | 1988 |
Chemical modification of the actin binding site of rabbit muscle aldolase by diethylpyrocarbonate.
Topics: Actins; Animals; Binding Sites; Diethyl Pyrocarbonate; Electrophoresis, Cellulose Acetate; Formates; Fructose-Bisphosphate Aldolase; Histidine; Hydroxylamines; Isoelectric Focusing; Muscles; Rabbits; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1988 |
Active site histidine in pig liver aminolevulic acid dehydratase modified by diethylpyrocarbonate and protected by Zn2+ ions.
Topics: Animals; Binding Sites; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Metals; Porphobilinogen Synthase; Swine; Zinc | 1988 |
Chemical modification of acyl-CoA:cholesterol O-acyltransferase. 1. Identification of acyl-CoA:cholesterol O-acyltransferase subtypes by differential diethyl pyrocarbonate sensitivity.
Topics: Acetates; Acetic Anhydrides; Animals; Aorta; Binding Sites; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Male; Microsomes; Microsomes, Liver; Rabbits; Sterol O-Acyltransferase; Tissue Distribution | 1988 |
Selective inhibition of histidine-modified pancreatic alpha-amylase by proteinaceous inhibitor from Phaseolus vulgaris.
Topics: alpha-Amylases; Animals; Binding Sites; Diethyl Pyrocarbonate; Enzyme Inhibitors; Fabaceae; Histidine; Kinetics; Plant Proteins; Plants, Medicinal; Swine; Trisaccharides | 1988 |
Evidence of histidine phosphorylation in isocitrate lyase from Escherichia coli.
Topics: Acid Phosphatase; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Isocitrate Lyase; Isoelectric Point; Oxo-Acid-Lyases; Phosphorylation | 1988 |
ras proteins enhance the phosphorylation of a 38 kDa protein (p38) in rat liver plasma membrane.
Topics: Animals; Diethyl Pyrocarbonate; Guanosine Diphosphate; Histidine; Liver; Male; Membrane Proteins; Oncogene Protein p21(ras); Oncogene Proteins, Viral; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Rats; Rats, Inbred Strains | 1987 |
Reaction of 5-enol-pyruvoylshikimate-3-phosphate synthase with diethyl pyrocarbonate: evidence for an essential histidine residue.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Escherichia coli; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Spectrophotometry; Structure-Activity Relationship; Transferases | 1987 |
Evidence for an essential histidine residue in D-xylose isomerases.
Topics: Aldose-Ketose Isomerases; Ammonium Hydroxide; Binding Sites; Carbohydrate Epimerases; Cations, Divalent; Diethyl Pyrocarbonate; Histidine; Hydroxides; Kinetics; Lactobacillus; Ligands; Spectrophotometry; Streptococcus | 1988 |
Chemical modification of rat cerebral cortex M1 muscarinic receptors: role of histidyl residues in antagonist and agonist binding.
Topics: Animals; Atropine; Benzilates; Binding Sites; Carbachol; Cerebral Cortex; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Oxotremorine; Piperidines; Rats; Receptors, Muscarinic; Synaptosomes | 1988 |
Arginyl and histidyl groups are essential for organic anion exchange in renal brush-border membrane vesicles.
Topics: Aldehydes; Animals; Arginine; Butanones; Diacetyl; Diethyl Pyrocarbonate; Dithiothreitol; Dogs; Formates; Histidine; Hydroxylamine; Hydroxylamines; Kidney Cortex; Kinetics; Microvilli; p-Aminohippuric Acid; Phenylglyoxal | 1988 |
Evidence for the essential histidine residue at the active site of glucose/xylose isomerase from Streptomyces.
Topics: Aldose-Ketose Isomerases; Binding Sites; Carbohydrate Epimerases; Catalysis; Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Kinetics; Methylene Blue; Oxidation-Reduction; Rose Bengal; Streptomyces; Tyrosine | 1988 |
Chemical modification studies on Achromobacter fischeri nitrite reductase.
Topics: Alcaligenes; Binding Sites; Diethyl Pyrocarbonate; Histidine; Kinetics; NADH, NADPH Oxidoreductases; Nitrite Reductases | 1987 |
Chemical modification of nitrate reductase from Amaranthus.
Topics: Binding Sites; Diethyl Pyrocarbonate; Histidine; Magnoliopsida; NAD; Nitrate Reductase; Nitrate Reductases; Plants | 1987 |
Chemical modification of histidine, tyrosine, tryptophan and cysteine residues in carp (Cyprinus carpio) muscle enolase.
Topics: Amino Acids; Animals; Bromosuccinimide; Carps; Cyprinidae; Cysteine; Diethyl Pyrocarbonate; Histidine; Muscles; Nitrogen; Phosphopyruvate Hydratase; Tetranitromethane; Tryptophan; Tyrosine | 1987 |
Evidence for an essential histidine in neutral endopeptidase 24.11.
Topics: Animals; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Kidney; Kinetics; Metalloendopeptidases; Neprilysin; Protein Binding; Rats | 1987 |
The presence of histidine residues at or near the C1q binding site of rabbit immunoglobulin G.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Complement Activating Enzymes; Complement C1; Complement C1q; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Immunoglobulin Fc Fragments; Immunoglobulin G; Kinetics; Rabbits; Spectrophotometry, Ultraviolet | 1987 |
Presence of a histidine at the active site of the neutral endopeptidase-24.11.
Topics: Animals; Binding Sites; Diethyl Pyrocarbonate; Endopeptidases; Epoxy Compounds; Histidine; Imidazoles; Neprilysin; Rabbits; Thermolysin; Time Factors | 1986 |
Possible role of histidine in the L-proline transport system of Saccharomyces cerevisiae.
Topics: Amino Acid Transport Systems, Neutral; Carrier Proteins; Diethyl Pyrocarbonate; Histidine; Kinetics; Proline; Saccharomyces cerevisiae | 1986 |
[Glutamate decarboxylase from Escherichia coli: catalytic role of the histidine residue].
Topics: Catalysis; Diethyl Pyrocarbonate; Escherichia coli; Glutamate Decarboxylase; Histidine; Kinetics; Substrate Specificity | 1986 |
Comparison of aspartate transcarbamoylases from wheat germ and Escherichia coli: functionally identical histidines in nonhomologous local sequences.
Topics: Amino Acid Sequence; Aspartate Carbamoyltransferase; Binding Sites; Cytidine Triphosphate; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Kinetics; Peptide Fragments; Plants; Species Specificity; Triticum; Uridine Monophosphate | 1986 |
Chemical modification of Escherichia coli RNA polymerase by diethyl pyrocarbonate: evidence of histidine requirement for enzyme activity and intrinsic zinc binding.
Topics: Diethyl Pyrocarbonate; DNA-Directed RNA Polymerases; Escherichia coli; Formates; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Macromolecular Substances; Protein Binding; Spectrophotometry; Zinc | 1986 |
Evidence for the involvement of histidine at the active site of glutathione S-transferase psi from human liver.
Topics: Binding Sites; Diethyl Pyrocarbonate; Glutathione; Glutathione Transferase; Histidine; Humans; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Liver | 1987 |
Enzymatic hydrolysis of diethylpyrocarbonate, a commonly used histidine modifying agent, by esterases.
Topics: Animals; Carboxylic Ester Hydrolases; Diethyl Pyrocarbonate; Ducks; Esterases; Formates; Fusarium; Histidine | 1987 |
[Functional role of histidine residues of alpha-ketoglutarate dehydrogenase].
Topics: Binding Sites; Catalysis; Diethyl Pyrocarbonate; Histidine; In Vitro Techniques; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Kinetics; Substrate Specificity | 1987 |
Chemical modification of essential histidine residues in Mn(III)-acid phosphatase by diethylpyrocarbonate in the presence of F- ion.
Topics: Acid Phosphatase; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Formates; Histidine; Iron | 1987 |
Diethyl pyrocarbonate inactivation of human placental aldehyde reductase II.
Topics: Carbohydrate Dehydrogenases; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Enzyme Activation; Female; Formates; Histidine; Humans; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; NADP; Placenta; Pregnancy; Spectrophotometry | 1987 |
Ethoxyformylation of histidine residues in equine growth hormone.
Topics: Amino Acids; Animals; Chromatography, High Pressure Liquid; Diethyl Pyrocarbonate; Formates; Growth Hormone; Histidine; Horses; Kinetics | 1987 |
Modification of bovine heart succinate dehydrogenase with ethoxyformic anhydride and rose bengal: evidence for essential histidyl residues protectable by substrates.
Topics: Animals; Cattle; Diethyl Pyrocarbonate; Formates; Histidine; Hydroxylamine; Hydroxylamines; Malonates; Mitochondria, Heart; Oxidation-Reduction; Photochemistry; Rose Bengal; Succinate Dehydrogenase | 1986 |
Chemical modification of the histidine residues of purified hepatic cytochrome P-450: influence on substrate binding and the haemoprotein spin state.
Topics: Animals; Benzphetamine; Binding Sites; Chemical Phenomena; Chemistry, Physical; Cytochrome P-450 Enzyme System; Diethyl Pyrocarbonate; Histidine; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Temperature | 1986 |
Acetyl-coenzyme A:alpha-glucosaminide N-acetyltransferase. Evidence for an active site histidine residue.
Topics: Acetyltransferases; Amino Acids; Animals; Binding Sites; Bromosuccinimide; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Diethyl Pyrocarbonate; Glucosamine; Histidine; Intracellular Membranes; Liver; Lysosomes; p-Chloromercuribenzoic Acid; Rats; Sulfhydryl Compounds | 1986 |
Chemical modification by diethylpyrocarbonate of an essential histidine residue in 3-ketovalidoxylamine A C-N lyase.
Topics: Amino Acids; Binding Sites; Carbon-Nitrogen Lyases; Diethyl Pyrocarbonate; Enzyme Reactivators; Flavobacterium; Formates; Histidine; Kinetics; Lyases; Spectrophotometry, Ultraviolet | 1986 |
Characterization of an essential histidine residue in thermophilic malate dehydrogenase.
Topics: Diethyl Pyrocarbonate; Histidine; Hot Temperature; Hydrogen-Ion Concentration; Malate Dehydrogenase; NAD; Oxidation-Reduction; Photochemistry; Thermus | 1986 |
The influence of uncoordinated histidines on iron release from transferrin. A chemical modification study.
Topics: Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen-Ion Concentration; Iron; Kinetics; Mathematics; Models, Chemical; Spectrophotometry; Transferrin | 1986 |
Hydrophobicity modulation as a tool for the purification of histidyl peptides.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Diethyl Pyrocarbonate; Histidine; Peptide Fragments; Spectrophotometry, Ultraviolet; Trypsin; Water | 1986 |
Microtubule assembly is dependent on a cluster of basic residues in alpha-tubulin.
Topics: Amino Acid Sequence; Animals; Brain; Cattle; Chickens; Cyanogen Bromide; Diethyl Pyrocarbonate; Histidine; Kinetics; Methylation; Microtubules; Oxidation-Reduction; Peptide Fragments; Rats; Schizosaccharomyces; Species Specificity; Swine; Tubulin | 1986 |
Modification of histidines in human prothrombin. Effect on the interaction of fibrinogen with thrombin from diethyl pyrocarbonate-modified prothrombin.
Topics: Diethyl Pyrocarbonate; Fibrinogen; Formates; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Mathematics; Peptide Hydrolases; Protein Conformation; Prothrombin; Thrombin | 1985 |
Modification of Escherichia coli ribosomes: in vitro termination is less dependent on histidine residues at the peptidyl transferase centre when ribosomes lack protein L11.
Topics: Acyltransferases; Chloramphenicol; Codon; Diethyl Pyrocarbonate; Dinitrofluorobenzene; Escherichia coli; Histidine; Kinetics; Peptide Chain Termination, Translational; Peptidyl Transferases; Ribosomal Proteins; Ribosomes | 1985 |
The presence of a histidine residue at or near the NADPH binding site of enoyl reductase domain on the multifunctional fatty acid synthetase of chicken liver.
Topics: Affinity Labels; Animals; Binding Sites; Binding, Competitive; Chickens; Diethyl Pyrocarbonate; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acid Synthases; Histidine; Hydrogen-Ion Concentration; Liver; NADP; Oxidoreductases | 1986 |
Chemical modification of sheep-liver 6-phosphogluconate dehydrogenase by diethylpyrocarbonate. Evidence for an essential histidine residue.
Topics: Animals; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Formates; Gluconates; Histidine; Kinetics; Liver; Models, Chemical; Phosphogluconate Dehydrogenase; Sheep | 1986 |
Chemical probes for the active site of aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Animals; Binding Sites; Cysteine; Diethyl Pyrocarbonate; Disulfiram; Histidine; Horses; In Vitro Techniques; Kinetics; Mitochondria, Liver | 1985 |
Diethylpyrocarbonate inactivation of NAD-malic enzyme from Ascaris suum.
Topics: Animals; Ascaris; Binding Sites; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Malate Dehydrogenase; Malates; NAD; Spectrometry, Fluorescence | 1985 |
Chemical modification of pig kidney 3,4-dihydroxyphenylalanine decarboxylase with diethyl pyrocarbonate. Evidence for an essential histidyl residue.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Binding Sites; Diethyl Pyrocarbonate; Dopa Decarboxylase; Formates; Histidine; Kidney; Kinetics; Protein Binding; Spectrophotometry, Ultraviolet; Swine | 1985 |
Diethyl pyrocarbonate, a histidine selective reagent, inhibits estrogen binding to receptor protein in rat uterus cytosol.
Topics: Animals; Binding Sites; Cytosol; Diethyl Pyrocarbonate; Estrogens; Female; Formates; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Rats; Rats, Inbred Strains; Receptors, Estrogen; Uterus | 1985 |
Active site histidine in spinach ribulosebisphosphate carboxylase/oxygenase modified by diethyl pyrocarbonate.
Topics: Amino Acid Sequence; Binding Sites; Diethyl Pyrocarbonate; Formates; Histidine; Kinetics; Peptide Fragments; Plants; Protein Binding; Ribulose-Bisphosphate Carboxylase; Species Specificity; Tritium; Trypsin | 1985 |
[Structural role of histidine residues in NAD(P)-glutamate dehydrogenase from the bovine liver].
Topics: Animals; Cattle; Circular Dichroism; Diethyl Pyrocarbonate; Glutamate Dehydrogenase; Histidine; In Vitro Techniques; Kinetics; Liver; NADP; Oxidation-Reduction; Photochemistry | 1985 |
Modification of histidine residues in yeast pyruvate kinase by diethylpyrocarbonate.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Catalysis; Depression, Chemical; Diethyl Pyrocarbonate; Enzyme Activation; Formates; Fructosephosphates; Histidine; Magnesium; Phosphoenolpyruvate; Protein Conformation; Pyruvate Kinase; Pyruvates; Saccharomyces; Spectrophotometry, Ultraviolet | 1974 |
Histidine modification with diethylpyrocarbonate induces a decrease in the binding of an antagonist, PK 11195, but not of an agonist, RO5-4864, of the peripheral benzodiazepine receptors.
Topics: Animals; Benzodiazepinones; Cell Membrane; Diethyl Pyrocarbonate; Formates; Histidine; Isoquinolines; Kidney; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1984 |
Chemical modifications of D-amino acid oxidase. Evidence for active site histidine, tyrosine, and arginine residues.
Topics: Animals; Arginine; D-Amino-Acid Oxidase; Diacetyl; Diethyl Pyrocarbonate; Dinitrofluorobenzene; Histidine; Hydroxylamines; Kidney; Kinetics; Spectrophotometry; Swine; Tyrosine | 1980 |
Chemical modification of dipeptidyl peptidase iv: involvement of an essential tryptophan residue at the substrate binding site.
Topics: Animals; Binding Sites; Bromosuccinimide; Diethyl Pyrocarbonate; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Histidine; Kinetics; Light; Photochemistry; Protease Inhibitors; Spectrometry, Fluorescence; Spectrophotometry; Swine; Tryptophan | 1984 |
Diethylpyrocarbonate inhibition of estrogen binding to rat alpha-fetoprotein: evidence that one or more histidine residues regulate estrogen binding.
Topics: alpha-Fetoproteins; Animals; Binding Sites; Diethyl Pyrocarbonate; Estrogen Antagonists; Estrogens; Formates; Histidine; Hydroxylamines; In Vitro Techniques; Protein Binding; Rats; Rats, Inbred BUF; Tryptophan | 1981 |
Kinetic study on chemical modification of Taka-amylase A. II. Ethoxycarbonylation of histidine residues.
Topics: alpha-Amylases; Amylases; Aspergillus; Aspergillus oryzae; Diethyl Pyrocarbonate; Formates; Histidine; Kinetics; Protein Binding | 1982 |
[Role of arginine and histidine residues in the biological activity of botulinic neurotoxin A].
Topics: Animals; Arginine; Botulinum Toxins; Cyclohexanones; Diacetyl; Diethyl Pyrocarbonate; Epitopes; Histidine; Protein Conformation | 1983 |
The modification of human immunoglobulin binding to staphylococcal protein A using diethylpyrocarbonate.
Topics: Diethyl Pyrocarbonate; Histidine; Humans; Immune Sera; Immunoglobulin Allotypes; Immunoglobulin G; Immunoglobulin Heavy Chains; Molecular Weight; Myeloma Proteins; Receptors, IgG; Receptors, Immunologic; Staphylococcal Protein A | 1982 |
Evidence for histidine residues in the immunoglobulin-binding site of human Clq.
Topics: Chemical Phenomena; Chemistry; Complement Activating Enzymes; Complement C1q; Diethyl Pyrocarbonate; Histidine; Humans; Receptors, IgG; Receptors, Immunologic; Temperature | 1983 |
Histidine modification with diethyl pyrocarbonate shows heterogeneity of benzodiazepine receptors.
Topics: Animals; Benzodiazepines; Brain; Chemical Phenomena; Chemistry; Diazepam; Diethyl Pyrocarbonate; Formates; Histidine; Male; Muscimol; Pentobarbital; Rats; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1981 |
Chemical modification of opiate receptors with ethoxyformic anhydride and photo-oxidation: evidence for essential histidyl residues.
Topics: Animals; beta-Endorphin; Brain; Diethyl Pyrocarbonate; Endorphins; Enkephalin, Methionine; Etorphine; Formates; Histidine; Kinetics; Male; Photolysis; Rats; Rats, Inbred Strains; Receptors, Opioid; Rose Bengal; Synaptosomes | 1982 |
Mechanism of lactose transport in Escherichia coli membrane vesicles: evidence for the involvement of histidine residue(s) in the response of the lac carrier to the proton electrochemical gradient.
Topics: Biological Transport; Cell Membrane; Diethyl Pyrocarbonate; Electrochemistry; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrogen-Ion Concentration; Kinetics; Lactose; Membrane Transport Modulators; Membrane Transport Proteins; Monosaccharide Transport Proteins; Photochemistry; Protons; Rose Bengal; Structure-Activity Relationship; Symporters | 1982 |
Direct measurement of lactose/proton symport in Escherichia coli membrane vesicles: further evidence for the involvement of histidine residue(s).
Topics: Biological Transport; Cell Membrane; Diethyl Pyrocarbonate; Diffusion; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrogen-Ion Concentration; Kinetics; Lactose; Membrane Transport Proteins; Monosaccharide Transport Proteins; Protons; Structure-Activity Relationship; Symporters | 1982 |
6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase from rat liver.
Topics: Adenosine Triphosphate; Animals; Diethyl Pyrocarbonate; Drug Stability; Fructose-Bisphosphatase; Fructosephosphates; Histidine; Hydrogen-Ion Concentration; Liver; Phosphofructokinase-1; Phosphoproteins; Phosphorylation; Rats; Trypsin | 1983 |
Ethoxyformylation of bovine growth hormone.
Topics: Animals; Binding Sites; Body Weight; Cattle; Diethyl Pyrocarbonate; Formates; Growth Hormone; Histidine; Indicators and Reagents; Kinetics; Liver; Rats; Receptors, Cell Surface; Receptors, Somatotropin | 1983 |
Metabolism of glycerate-2,3-P2--V. Histidine-specific reagents inactivate the phosphoglycerate mutase, glycerate-2,3-P2 synthase and glycerate-2,3-P2 phosphatase activities of rabbit muscle phosphoglycerate mutase.
Topics: 2,3-Diphosphoglycerate; Animals; Diethyl Pyrocarbonate; Diphosphoglyceric Acids; Histidine; Muscles; Phosphoglycerate Mutase; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphotransferases; Photochemistry; Rabbits; Rose Bengal | 1983 |
The cytochrome c peroxidase-cytochrome c electron transfer complex. The role of histidine residues.
Topics: Amino Acids; Cytochrome c Group; Cytochrome-c Peroxidase; Diethyl Pyrocarbonate; Electron Transport; Histidine; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Models, Molecular; Peroxidases; Protein Binding; Protein Conformation; Saccharomyces cerevisiae | 1984 |
Regulation of C4 photosynthesis: identification of a catalytically important histidine residue and its role in the regulation of pyruvate,Pi dikinase.
Topics: Adenosine Diphosphate; Amino Acids; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Histidine; Oxalates; Oxalic Acid; Phosphorylation; Phosphotransferases; Photochemistry; Pyruvate, Orthophosphate Dikinase; Zea mays | 1984 |
Involvement of histidine and tryptophan residues of glutamine binding protein in the interaction with membrane-bound components of the glutamine transport system of Escherichia coli.
Topics: Biological Transport, Active; Cell Membrane; Diethyl Pyrocarbonate; Escherichia coli; Glutamine; Histidine; Kinetics; Tryptophan | 1983 |
Involvement of histidine residues in the activity of horse liver alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Apoenzymes; Binding Sites; Diethyl Pyrocarbonate; Histidine; Horses; Kinetics; Liver; NAD; Protein Conformation; X-Ray Diffraction | 1983 |
Chemical modification of essential histidine residues in aspartase with diethylpyrocarbonate.
Topics: Ammonia-Lyases; Aspartate Ammonia-Lyase; Binding Sites; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Escherichia coli; Formates; Histidine; Hydrogen-Ion Concentration | 1984 |
Effect of diethylpyrocarbonate on the biological activities of botulinum neurotoxin types A and E.
Topics: Animals; Botulinum Toxins; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Formates; Histidine; Immunochemistry; Immunodiffusion; Mice; Neurotoxins; Rabbits; Structure-Activity Relationship; Toxoids | 1984 |
The pH dependence and group modification of beta-D-xylosidase from Bacillus pumilus: evidence for sulfhydryl and histidyl groups.
Topics: Allosteric Site; Bacillus; Catalysis; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Kinetics; Methyl Methanesulfonate; Protein Binding; Sulfhydryl Compounds; Xylosidases | 1984 |
Effect of chemical modification on the cryoprecipitation of monoclonal human cryoglobulin M.
Topics: Anisoles; Arginine; Cold Temperature; Cryoglobulins; Diethyl Pyrocarbonate; Formaldehyde; Histidine; Humans; Immunoglobulin M; Lysine; Protein Binding; Trinitrobenzenesulfonic Acid; Tryptophan; Tyrosine; Waldenstrom Macroglobulinemia | 1984 |
Inhibition of mitochondrial NADH:ubiquinone oxidoreductase by ethoxyformic anhydride.
Topics: Animals; Cattle; Diethyl Pyrocarbonate; Electron Transport; Formates; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Meperidine; Mitochondria, Heart; NAD; NAD(P)H Dehydrogenase (Quinone); NADH, NADPH Oxidoreductases; Quinone Reductases; Tyrosine | 1984 |
Conformationally important histidine residue in glutamate dehydrogenase from Neurospora crassa.
Topics: Diethyl Pyrocarbonate; Glutamate Dehydrogenase; Glutamates; Histidine; Hydrogen-Ion Concentration; Ketoglutaric Acids; NADP; Neurospora; Neurospora crassa; Protein Conformation; Spectrometry, Fluorescence | 1980 |
Chemical modification of histidine residues in rabbit liver glutathione reductase.
Topics: Animals; Dansyl Compounds; Diethyl Pyrocarbonate; Glutathione Reductase; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Liver; Rabbits; Spectrometry, Fluorescence; Structure-Activity Relationship | 1984 |
Involvement of some amino acid residues in the enzymatic activity of solubilized cerebral fucosyltransferase.
Topics: Animals; Arginine; Binding Sites; Brain; Butanones; Diacetyl; Diethyl Pyrocarbonate; Formates; Fucosyltransferases; Hexosyltransferases; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Methane; Sheep; Tetranitromethane; Tyrosine | 1984 |
Conformational integrity of human alpha-thrombin.
Topics: Circular Dichroism; Diethyl Pyrocarbonate; Histidine; Hot Temperature; Humans; Hydrogen-Ion Concentration; Protein Conformation; Spectrophotometry, Ultraviolet; Sulfonium Compounds; Thrombin; Tosyllysine Chloromethyl Ketone | 1984 |
Identification of active-site residues of sheep liver serine hydroxymethyltransferase.
Topics: Animals; Arginine; Binding Sites; Cysteine; Diethyl Pyrocarbonate; Ethylmaleimide; Glycine Hydroxymethyltransferase; Histidine; Kinetics; Liver; Phenylglyoxal; Sheep; Spectrophotometry; Transferases | 1984 |
Histidyl residues at the active site of the Na/succinate co-transporter in rabbit renal brush borders.
Topics: Animals; Binding Sites; Biological Transport; Carrier Proteins; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kidney Cortex; Lactates; Lactic Acid; Lithium; Malates; Microvilli; Monosaccharide Transport Proteins; Rabbits; Sodium; Succinates; Succinic Acid | 1984 |
Chemical modification of Corynebacterium sarcosine oxidase: role of sulfhydryl and histidyl groups.
Topics: Chemical Phenomena; Chemistry; Corynebacterium; Diethyl Pyrocarbonate; Histidine; Metals; Oxidoreductases, N-Demethylating; Sarcosine Oxidase; Sulfhydryl Compounds; Sulfhydryl Reagents | 1983 |
Essential histidine residues of alpha-ketoglutarate dehydrogenase from pigeon breast muscle.
Topics: Animals; Binding Sites; Columbidae; Diethyl Pyrocarbonate; Histidine; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Kinetics; Muscles | 1983 |
Diethylpyrocarbonate, a histidine selective reagent, inhibits progestin binding to chick oviduct cytosol.
Topics: Animals; Chemical Phenomena; Chemistry; Chickens; Cytosol; Diethyl Pyrocarbonate; Female; Formates; Histidine; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Oviducts; Progestins; Promegestone; Receptors, Progesterone | 1983 |
Essential histidyl residues of ferredoxin-NADP+ oxidoreductase revealed by diethyl pyrocarbonate inactivation.
Topics: Diethyl Pyrocarbonate; Dihydrolipoamide Dehydrogenase; Ferredoxin-NADP Reductase; Ferredoxins; Formates; Histidine; NADH, NADPH Oxidoreductases; NADP; Nucleotides; Spectrophotometry, Ultraviolet | 1983 |
Modification of rat liver iodothyronine 5'-deiodinase activity with diethylpyrocarbonate and rose bengal; evidence for an active site histidine residue.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Iodide Peroxidase; Microsomes, Liver; Oxidation-Reduction; Peroxidases; Photochemistry; Rats; Rose Bengal | 1984 |
Modification of the insulin receptor by diethyl pyrocarbonate: effect on insulin binding and action.
Topics: Adipose Tissue; Animals; Cell Membrane; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Formates; Glucose; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; In Vitro Techniques; Insulin; Liver; Male; Rats; Rats, Inbred Strains; Receptor, Insulin | 1982 |
The inactivation of thymidylate synthase by diethyl pyrocarbonate.
Topics: Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Enzyme Activation; Formates; Histidine; Hydroxylamines; Kinetics; Lacticaseibacillus casei; Methyltransferases; Thymidylate Synthase | 1981 |
Reversible chemical modification of the scrapie agent.
Topics: Animals; Biological Assay; Brain; Chemical Phenomena; Chemistry; Cricetinae; Diethyl Pyrocarbonate; Histidine; Prions; Ribonucleases; Serum Albumin, Bovine; Viral Proteins | 1981 |
Diethyl pyrocarbonate inactivates swine pepsinogen by reaction at amino groups.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, High Pressure Liquid; Diethyl Pyrocarbonate; Formates; Histidine; Kinetics; Pepsin A; Pepsinogens; Peptide Fragments; Protein Binding; Swine; Trypsin | 1981 |
Modification of active site histidine in ribulosebisphosphate carboxylase/oxygenase.
Topics: Binding Sites; Carboxy-Lyases; Diethyl Pyrocarbonate; Formates; Hexosediphosphates; Histidine; Kinetics; Oxygenases; Plants; Rhodospirillum rubrum; Ribulose-Bisphosphate Carboxylase; Ribulosephosphates; Spectrophotometry, Ultraviolet | 1982 |
Inactivation of dihydrofolate reductase from Lactobacillus casei by diethyl pyrocarbonate.
Topics: Binding Sites; Diethyl Pyrocarbonate; Folic Acid; Folic Acid Antagonists; Formates; Histidine; Hydroxylamines; Lacticaseibacillus casei; NADP | 1982 |
Evidence for an essential histidine residue in S-adenosylhomocysteinase from rat liver.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Chromatography, Gel; Diethyl Pyrocarbonate; Histidine; Hydrolases; Kinetics; Liver; NAD; Rats; Spectrometry, Fluorescence | 1983 |
Chemical modification of spinach ferredoxin with diethylpyrocarbonate: evidence for the essential nature of the histidyl residue.
Topics: Diethyl Pyrocarbonate; Ferredoxins; Formates; Histidine; Photochemistry; Photosynthesis; Structure-Activity Relationship | 1983 |
Possible occurrence and role of an essential histidyl residue in succinate dehydrogenase.
Topics: Animals; Cattle; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Kinetics; Mitochondria, Heart; Spectrophotometry, Ultraviolet; Submitochondrial Particles; Succinate Dehydrogenase | 1981 |
The inactivation of saccharopine dehydrogenase (L-lysine-forming) by diethyl pyrocarbonate.
Topics: Binding Sites; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Formates; Histidine; Kinetics; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Saccharomyces cerevisiae; Saccharopine Dehydrogenases; Spectrophotometry, Ultraviolet | 1980 |
Role of essential histidine residues in L-alpha-hydroxy acid oxidase from rat kidney.
Topics: Alcohol Oxidoreductases; Animals; Binding Sites; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Hydroxy Acids; Kidney; Kinetics; Protein Binding; Rats; Spectrophotometry, Ultraviolet | 1980 |
Nuclear magnetic resonance and chemical modification studies of the role of the metal in yeast aldolase.
Topics: Copper; Cysteine; Diethyl Pyrocarbonate; Formates; Fructose-Bisphosphate Aldolase; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Protein Binding; Saccharomyces cerevisiae; Zinc | 1981 |
Sulfhydryl and histidinyl residues in the flavoenzyme alcohol oxidase from Candida boidinii.
Topics: Alcohol Oxidoreductases; Candida; Cations; Diethyl Pyrocarbonate; Histidine; Macromolecular Substances; Molecular Weight; Spectrophotometry; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfhydryl Reagents | 1981 |
Modification of the essential amino acids of human pancreatic carboxylic-ester hydrolase.
Topics: Carboxylesterase; Carboxylic Ester Hydrolases; Diethyl Pyrocarbonate; Formates; Histidine; Humans; Indicators and Reagents; Isoxazoles; Kinetics; Organophosphorus Compounds; Oxazoles; Pancreas | 1982 |
A histidine residue in p-hydroxybenzoate hydroxylase essential for binding of reduced nicotinamide adenine dinucleotide phosphate.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Diethyl Pyrocarbonate; Dithiothreitol; Formates; Histidine; Hydroxylamines; Kinetics; Mixed Function Oxygenases; NADP; Pseudomonas | 1982 |
Interactions of the histidine-rich glycoprotein of serum with metals.
Topics: Animals; Binding Sites; Cations, Divalent; Circular Dichroism; Diethyl Pyrocarbonate; Glycoproteins; Heme; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Protein Binding; Protein Conformation; Proteins; Rabbits; Spectrometry, Fluorescence; Spectrophotometry | 1981 |
Diethylpyrocarbonate inhibition of estradiol receptor binding to oligonucleotides.
Topics: Amino Acids; Animals; Cattle; Diethyl Pyrocarbonate; Estradiol; Female; Formates; Histidine; Hydroxylamine; Hydroxylamines; Imidazoles; Oligonucleotides; Pyridoxal Phosphate; Receptors, Estradiol; Receptors, Estrogen; Uterus | 1981 |
Modification of enoyl-CoA hydratase using diethyl pyrocarbonate.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Cattle; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Enoyl-CoA Hydratase; Formates; Histidine; Hydro-Lyases; Kinetics; Spectrophotometry, Ultraviolet; Tritium | 1981 |
The chemical reactivity of the histidine-195 residue in lactate dehydrogenase thiomethylated at the cysteine-165 residue.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Ligands; Methyl Methanesulfonate; Pyruvates; Sulfides | 1981 |
Comparative study of the iron-binding properties of transferrins. Differences in the involvement of histidine residues as revealed by carbethoxylation.
Topics: Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Chickens; Diethyl Pyrocarbonate; Histidine; Humans; Iron; Kinetics; Protein Binding; Rabbits; Species Specificity; Transferrin | 1981 |
Effect of histidine modification on the aging of organophosphate-inhibited acetylcholinesterase.
Topics: Animals; Binding Sites; Cattle; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diethyl Pyrocarbonate; Erythrocytes; Histidine; Organophosphorus Compounds; Pralidoxime Compounds; Time Factors | 1981 |
Modification of histidine at the active site of spinach ribulose bisphosphate carboxylase.
Topics: Binding Sites; Carboxy-Lyases; Diethyl Pyrocarbonate; Formates; Histidine; Kinetics; Macromolecular Substances; Molecular Weight; Plants; Ribulose-Bisphosphate Carboxylase | 1980 |
The pH dependence and modification by diethyl pyrocarbonate of isocitrate lyase from Phycomyces blakesleeanus.
Topics: Binding Sites; Chromatography, High Pressure Liquid; Diethyl Pyrocarbonate; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration; Isocitrate Lyase; Isocitrates; Kinetics; Magnesium; Peptide Fragments; Phycomyces; Trypsin | 1995 |
Single-channel currents from diethylpyrocarbonate-modified NMDA receptors in cultured rat brain cortical neurons.
Topics: Animals; Brain; Cells, Cultured; Diethyl Pyrocarbonate; Histidine; Hydroxylamine; Hydroxylamines; Ion Channel Gating; Ion Channels; Kinetics; Magnesium; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Zinc | 1995 |
Regulation of skeletal-muscle AMP deaminase: involvement of histidine residues in the pH-dependent inhibition of the rabbit enzyme by ATP.
Topics: Adenosine Triphosphate; Allosteric Regulation; Amino Acid Sequence; AMP Deaminase; Animals; Diethyl Pyrocarbonate; Guanosine Triphosphate; Histidine; Hydrogen-Ion Concentration; Molecular Sequence Data; Muscle, Skeletal; Rabbits; Trypsin | 1995 |
Mechanistic studies on malate dehydrogenase from Escherichia coli.
Topics: Binding Sites; Deuterium; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Iodoacetates; Iodoacetic Acid; Kinetics; Malate Dehydrogenase; NAD | 1995 |
Mutational analysis of transmembrane histidines in the amiloride-sensitive Na+/H+ exchanger.
Topics: Amiloride; Amino Acids; Animals; Base Sequence; Cell Line; Cimetidine; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Membranes; Mice; Molecular Probes; Molecular Sequence Data; Mutagenesis, Site-Directed; Sodium-Hydrogen Exchangers | 1995 |
Evidence that His110 of the protein FadL in the outer membrane of Escherichia coli is involved in the binding and uptake of long-chain fatty acids: possible role of this residue in carboxylate binding.
Topics: Alanine; Amino Acid Sequence; Bacterial Outer Membrane Proteins; Base Sequence; Binding Sites; Binding, Competitive; Biological Transport; Diethyl Pyrocarbonate; Escherichia coli; Escherichia coli Proteins; Fatty Acid Transport Proteins; Genes, Bacterial; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oleic Acid; Oleic Acids; Oligodeoxyribonucleotides; Plasmids; Point Mutation; Recombinant Proteins | 1995 |
Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH. Evidence that the pore open-closed probability is regulated by reversible histidine protonation.
Topics: Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cyclosporine; Diethyl Pyrocarbonate; Fluoresceins; Fluorescent Dyes; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Ion Channel Gating; Ion Channels; Kinetics; Mitochondria, Liver; Rats | 1993 |
Effect of chemical modification of extracellular histidyl residues on the channel properties of the nicotinic acetylcholine receptor.
Topics: Bungarotoxins; Clone Cells; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Iodine Radioisotopes; Ion Channels; Kinetics; Membrane Potentials; Receptors, Cholinergic | 1993 |
Exposure of hydrophobic surfaces on the chaperonin GroEL oligomer by protonation or modification of His-401.
Topics: Anilino Naphthalenesulfonates; Chaperonin 60; Diethyl Pyrocarbonate; Fluorescent Dyes; Histidine; Hydrogen-Ion Concentration; Kinetics; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Thiosulfate Sulfurtransferase; Urea | 1995 |
Mutations within a highly conserved sequence present in the X region of phosphoinositide-specific phospholipase C-delta 1.
Topics: Amino Acid Sequence; Animal Population Groups; Animals; Base Sequence; Calcium; Circular Dichroism; Diethyl Pyrocarbonate; Genes; Histidine; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositol Phosphates; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Protein Conformation; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 1995 |
Expression, purification and characterization of 1-aminocyclopropane-1-carboxylate oxidase from tomato in Escherichia coli.
Topics: Amino Acid Oxidoreductases; Base Sequence; Carbon Dioxide; Catalase; Cloning, Molecular; Diethyl Pyrocarbonate; Dithiothreitol; DNA, Complementary; Enzyme Induction; Escherichia coli; Histidine; Hydroxylamine; Hydroxylamines; Iron; Isopropyl Thiogalactoside; Molecular Sequence Data; Plant Proteins; Polymerase Chain Reaction; Recombinant Fusion Proteins; Serum Albumin, Bovine; Solanum lycopersicum; Stereoisomerism; Substrate Specificity; Transfection | 1995 |
Mechanistic studies on CDP-6-deoxy-L-threo-D-glycero-4-hexulose 3-dehydrase identification of His-220 as the active-site base by chemical modification and site-directed mutagenesis.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Catalysis; Diethyl Pyrocarbonate; DNA Primers; Histidine; Hydro-Lyases; Hydroxylamine; Hydroxylamines; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Alignment; Yersinia pseudotuberculosis | 1995 |
Histidine residues 139, 363 and 500 are essential for catalytic activity of cofactor-independent phosphoglyceromutase from developing endosperm of the castor plant.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Catalysis; Diethyl Pyrocarbonate; DNA Primers; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoglycerate Mutase; Plants, Toxic; Recombinant Proteins; Ricinus communis; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship | 1995 |
Site-directed mutagenesis of His343-->Ala in Citrobacter freundii tyrosine phenol-lyase. Effects on the kinetic mechanism and rate-determining step.
Topics: Alanine; Amino Acid Sequence; Base Sequence; Citrobacter freundii; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Sequence Alignment; Sequence Homology, Amino Acid; Spectrum Analysis; Tryptophanase; Tyrosine Phenol-Lyase | 1995 |
Chemical modification of a cloned glutathione S-transferase from Schistosoma japonicum: evidence for an essential histidine residue.
Topics: Animals; Diethyl Pyrocarbonate; Glutathione; Glutathione Transferase; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Mutagenesis, Site-Directed; Recombinant Proteins; Schistosoma japonicum | 1995 |
Function of conserved histidine residues in mammalian dihydroorotase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Conserved Sequence; Cricetinae; Diethyl Pyrocarbonate; Dihydroorotase; Escherichia coli; Genetic Complementation Test; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Binding; Sequence Homology, Amino Acid; Zinc | 1995 |
Effect of metal ions on sucrose synthase from rice grains--a study on enzyme inhibition and enzyme topography.
Topics: Cations, Divalent; Chromatography, Affinity; Copper; Cysteine; Diethyl Pyrocarbonate; Dithiothreitol; Edetic Acid; Glucosyltransferases; Glutathione; Histidine; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Mercaptoethanol; Oryza; Seeds | 1995 |
Evidence for an essential histidine residue located in the binding site of the cysteine-specific lysosomal transport protein.
Topics: Binding Sites; Biological Transport; Carrier Proteins; Cell Line; Cysteine; Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen-Ion Concentration; Lysosomes; Phosphatidylcholines | 1995 |
Histidine-254 is essential for the inactivation of phosphotriesterase with the alkynyl phosphate esters and diethyl pyrocarbonate.
Topics: Alkynes; Aryldialkylphosphatase; Binding Sites; Diethyl Pyrocarbonate; Esterases; Histidine; Kinetics; Mutagenesis, Site-Directed; Phosphates; Pseudomonas; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1995 |
Role of histidine residues in the adenosine A2a receptor ligand binding site.
Topics: Adenosine; Animals; Antihypertensive Agents; Binding Sites; Binding, Competitive; Cell Membrane; Corpus Striatum; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Kinetics; Ligands; Phenethylamines; Radioligand Assay; Rats; Receptors, Purinergic P1; Tritium | 1994 |
Investigation of the active site of the cyanogenic beta-D-glucosidase (linamarase) from Manihot esculenta Crantz (cassava). I. Evidence for an essential carboxylate and a reactive histidine residue in a single catalytic center.
Topics: beta-Glucosidase; Binding Sites; Carbodiimides; Catalysis; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Hydroxylamine; Hydroxylamines; Isoxazoles; Kinetics; Manihot; Nitriles; Spectrophotometry; Substrate Specificity | 1994 |
Reaction of the N-terminal methionine residues in cyanase with diethylpyrocarbonate.
Topics: Amino Acid Sequence; Binding Sites; Carbon-Nitrogen Lyases; Diethyl Pyrocarbonate; Disulfides; Escherichia coli; Histidine; Kinetics; Lyases; Macromolecular Substances; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Structure-Activity Relationship | 1994 |
Essential histidine at the active site of sorghum leaf NADP-dependent malate dehydrogenase.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Diethyl Pyrocarbonate; DNA Mutational Analysis; DNA Primers; DNA, Complementary; Histidine; Malate Dehydrogenase; Mass Spectrometry; Molecular Sequence Data; Peptide Mapping; Peptides; Plants, Edible; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship | 1994 |
Catalytically important domains of rat carnitine palmitoyltransferase II as determined by site-directed mutagenesis and chemical modification. Evidence for a critical histidine residue.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Carnitine O-Palmitoyltransferase; Catalysis; Citrate (si)-Synthase; Diethyl Pyrocarbonate; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship | 1994 |
Chemical modifications of melatonin receptors in chicken brain.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cell Membrane; Chickens; Chloromercuribenzoates; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Ethylmaleimide; GTP-Binding Proteins; Histidine; Kinetics; Ligands; Male; Melatonin; p-Chloromercuribenzoic Acid; Protein Binding; Receptors, Cell Surface; Receptors, Melatonin; Superior Colliculi; Tetranitromethane; Tyrosine | 1994 |
Evidence for an essential histidine residue on active site of human urinary DNase I: carboxymethylation and carbethoxylation.
Topics: Acetates; Binding Sites; Deoxyribonucleases; Diethyl Pyrocarbonate; Histidine; Humans; Iodoacetates; Spectrophotometry, Ultraviolet | 1994 |
Mutagenesis of rat liver arginase expressed in Escherichia coli: role of conserved histidines.
Topics: Animals; Arginase; Circular Dichroism; Diethyl Pyrocarbonate; Edetic Acid; Escherichia coli; Histidine; Humans; Kinetics; Liver; Manganese; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Structure, Secondary; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship | 1994 |
Modification of pig kidney diamine oxidase with ethoxyformic anhydride and rose bengal: evidence for essential histidyl residue at the active site.
Topics: Amine Oxidase (Copper-Containing); Animals; Binding Sites; Diethyl Pyrocarbonate; Histidine; Hydroxylamine; Hydroxylamines; Kidney; Kinetics; Oxidants, Photochemical; Putrescine; Rose Bengal; Spectrometry, Fluorescence; Substrate Specificity; Swine | 1994 |
Chemical modification of aminopeptidase isolated from Pronase.
Topics: Aminopeptidases; Arginine; Calcium; Calcium Chloride; Catalysis; Circular Dichroism; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Kinetics; Pronase; Tyrosine | 1994 |
Spectroscopic and kinetic studies of the histidine residues of bovine low-molecular-weight phosphotyrosyl protein phosphatase.
Topics: Animals; Base Sequence; Cattle; Diethyl Pyrocarbonate; DNA Primers; Histidine; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Weight; Mutation; Protein Tyrosine Phosphatases | 1994 |
Involvement of essential histidine residue(s) in the activity of Ehrlich cell plasma membrane NADH-ferricyanide oxidoreductase.
Topics: Animals; Binding Sites; Carcinoma, Ehrlich Tumor; Cell Membrane; Chlorides; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; NADH, NADPH Oxidoreductases; Rose Bengal; Tumor Cells, Cultured; Zinc Compounds | 1994 |
Chemical modification of beta-glucosidase from Trichoderma reesei QM 9414.
Topics: beta-Glucosidase; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Kinetics; Quinolines; Spectrophotometry, Ultraviolet; Trichoderma | 1993 |
Inhibition of inositol 1,3,4-trisphosphate 5/6-kinase by amino acid modifying agents.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Animals; Arginine; Benzenesulfonates; Brain; Diethyl Pyrocarbonate; Fluorescein-5-isothiocyanate; Histidine; Imidoesters; Indicators and Reagents; Lysine; Phosphotransferases (Alcohol Group Acceptor); Rose Bengal; Swine | 1993 |
Chemical modification of human UDP-glucuronosyltransferase UGT1*6 by diethyl pyrocarbonate: possible involvement of a histidine residue in the catalytic process.
Topics: Affinity Labels; Animals; Catalysis; Cell Line; Cricetinae; Cricetulus; Diethyl Pyrocarbonate; Enzyme Activation; Glucuronates; Glucuronosyltransferase; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Hymecromone; Kinetics; Lung; Recombinant Proteins; Uridine Diphosphate Glucuronic Acid | 1994 |
The role of His66 and His72 in the reaction mechanism of bovine liver low-M(r) phosphotyrosine protein phosphatase.
Topics: Amino Acid Sequence; Animals; Biological Evolution; Catalysis; Cattle; Conserved Sequence; Diethyl Pyrocarbonate; Histidine; Humans; Kinetics; Liver; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid | 1994 |
The effects of histidine residue modification on the immune precipitating ability of rabbit IgG.
Topics: Animals; Antigen-Antibody Complex; Complement C1q; Diethyl Pyrocarbonate; Histidine; Immunoglobulin Fab Fragments; Immunoglobulin G; Kinetics; Precipitin Tests; Rabbits; Staphylococcal Protein A | 1994 |
The catechol 2,3-dioxygenase gene of Rhodococcus rhodochrous CTM: nucleotide sequence, comparison with isofunctional dioxygenases and evidence for an active-site histidine.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Catechol 2,3-Dioxygenase; Cloning, Molecular; Consensus Sequence; Diethyl Pyrocarbonate; Dioxygenases; Genes, Bacterial; Histidine; Molecular Sequence Data; Oxygenases; Pseudomonas; Recombinant Fusion Proteins; Rhodococcus; Sequence Alignment; Sequence Homology, Amino Acid | 1994 |
Chemical modification of histidine residue in substrate-binding domain of carbonyl reductase from rabbit kidney.
Topics: Alcohol Oxidoreductases; Animals; Binding Sites; Diethyl Pyrocarbonate; Histidine; Kidney; Kinetics; NADP; Oxidation-Reduction; Pyridines; Rabbits; Structure-Activity Relationship; Substrate Specificity | 1993 |
Characterization of a polyhistidine-tagged form of human myristoyl-CoA: protein N-myristoyltransferase produced in Escherichia coli.
Topics: Acylation; Acyltransferases; Amino Acid Sequence; Base Sequence; Diethyl Pyrocarbonate; DNA Primers; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fatty Acids; Histidine; Humans; Hydrogen-Ion Concentration; Iodoacetamide; Isoelectric Focusing; Kinetics; Molecular Sequence Data; Peptides; Recombinant Proteins; Substrate Specificity | 1994 |
Characterization of the type I dehydroquinase from Salmonella typhi.
Topics: Circular Dichroism; Diethyl Pyrocarbonate; Escherichia coli; Guanidine; Guanidines; Histidine; Hot Temperature; Hydro-Lyases; Kinetics; Oxidation-Reduction; Protein Conformation; Protein Denaturation; Recombinant Proteins; Salmonella typhi; Spectrometry, Fluorescence; Spectrophotometry; Succinimides; Tryptophan | 1993 |
Histidine residues are involved in translocation-coupled ATP hydrolysis by the Sec-A protein.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Bacterial Outer Membrane Proteins; Bacterial Proteins; Biological Transport, Active; Diethyl Pyrocarbonate; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrolysis; Membrane Transport Proteins; Protein Precursors; SEC Translocation Channels; SecA Proteins | 1993 |
Chemical modification of tissue inhibitor of metalloproteinases-1 and its inactivation by diethyl pyrocarbonate.
Topics: Amino Acid Sequence; Carbon Radioisotopes; Diethyl Pyrocarbonate; Glycoproteins; Histidine; Humans; Matrix Metalloproteinase 3; Metalloendopeptidases; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Recombinant Proteins; Tissue Inhibitor of Metalloproteinases; Trypsin | 1993 |
Accessibility to modification of histidine residues of RecA protein upon DNA and cofactor binding.
Topics: Adenosine Triphosphate; Chromatography, High Pressure Liquid; Diethyl Pyrocarbonate; DNA; DNA, Single-Stranded; Histidine; Rec A Recombinases | 1993 |
Molecular characterization of flavanone 3 beta-hydroxylases. Consensus sequence, comparison with related enzymes and the role of conserved histidine residues.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Consensus Sequence; Diethyl Pyrocarbonate; DNA, Complementary; Histidine; Isoelectric Point; Leucine; Metalloproteins; Mixed Function Oxygenases; Molecular Sequence Data; Molecular Weight; Nonheme Iron Proteins; Plants; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 1993 |
Chemical and kinetic evidence for an essential histidine residue in the electron transfer from aromatic donor to horseradish peroxidase compound I.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Computer Simulation; Diethyl Pyrocarbonate; Electron Transport; Guaiacol; Histidine; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Protein Conformation; Spectrophotometry | 1993 |
Histidine substitution identifies a surface position and confers Cs+ selectivity on a K+ pore.
Topics: Animals; Biophysical Phenomena; Biophysics; Cations; Cesium; Diethyl Pyrocarbonate; Electric Conductivity; Female; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Mutagenesis, Site-Directed; Oocytes; Permeability; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Zinc | 1993 |
The effect of chemical modification of basic amino acid residues on the activation and amidolytic activity of Hageman factor (factor XII).
Topics: Amides; Amino Acids; Arginine; Diethyl Pyrocarbonate; Factor XII; Factor XIIa; Histidine; Humans; Lysine; Phenylglyoxal; Serum Albumin, Bovine; Structure-Activity Relationship; Trinitrobenzenesulfonic Acid | 1993 |
Carbethoxylation of coordinated histidine by diethylpyrocarbonate.
Topics: Circular Dichroism; Cobalt; Diethyl Pyrocarbonate; Histidine; Imidazoles; Models, Molecular; Rotation | 1993 |
Evidence for alpha-proton abstraction and carbanion formation involving a functional histidine residue in lentil seedling amine oxidase.
Topics: Amine Oxidase (Copper-Containing); Binding Sites; Diethyl Pyrocarbonate; Fabaceae; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Structural; Oxidoreductases Acting on CH-NH Group Donors; Plants, Medicinal; Polyamines; Putrescine; Substrate Specificity; Tetranitromethane | 1993 |
The vanadium chloroperoxidase from the fungus, Curvularia inaequalis. Evidence for the involvement of a histidine residue in the binding of vanadate.
Topics: Binding Sites; Chloride Peroxidase; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Mitosporic Fungi; Vanadates | 1993 |
[Prostaglandin H synthase. Chemical modification of histidine residues in various forms of the enzyme by diethylpyrocarbonate].
Topics: Catalysis; Cyclooxygenase Inhibitors; Diethyl Pyrocarbonate; Histidine; Hydrolysis; Kinetics; Prostaglandin-Endoperoxide Synthases; Trypsin | 1993 |
Site-directed mutagenesis of Klebsiella aerogenes urease: identification of histidine residues that appear to function in nickel ligation, substrate binding, and catalysis.
Topics: Base Sequence; Binding Sites; Catalysis; Diethyl Pyrocarbonate; DNA, Bacterial; Enzyme Stability; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Klebsiella pneumoniae; Molecular Sequence Data; Mutagenesis, Site-Directed; Nickel; Urease | 1993 |
Unusual reactivity of Tyr-7 of GSH transferase P1-1.
Topics: Diethyl Pyrocarbonate; Female; Glutathione Transferase; Histidine; Humans; Kidney; Placenta; Pregnancy; Tyrosine | 1993 |
Inactivation of the endogenous argininosuccinate lyase activity of duck delta-crystallin by modification of an essential histidine residue with diethyl pyrocarbonate.
Topics: Animals; Arginine; Argininosuccinate Lyase; Crystallins; Diethyl Pyrocarbonate; Ducks; Fumarates; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Spectrometry, Fluorescence | 1993 |
Histidine 296 is essential for the catalysis in Lactobacillus plantarum D-lactate dehydrogenase.
Topics: Amino Acid Sequence; Base Sequence; Catalysis; Cloning, Molecular; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactobacillus; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Recombinant Proteins; Restriction Mapping | 1993 |
Guanine nucleotide-specific phosphate transfer by guanine nucleotide-binding regulatory protein beta-subunits. Characterization of the phosphorylated amino acid.
Topics: Biological Transport; Cell Membrane; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histidine; Humans; Hydroxylamine; Hydroxylamines; Kinetics; Leukemia, Promyelocytic, Acute; Macromolecular Substances; Magnesium; Manganese; Membrane Proteins; Molecular Weight; Phosphorus Radioisotopes; Phosphorylation; Tumor Cells, Cultured | 1993 |
Chemical modification of bacteriophage T4 deoxynucleotide kinase. Evidence of a single catalytic region.
Topics: Amino Acid Sequence; Bacteriophage T4; Binding Sites; Chromatography, High Pressure Liquid; Deoxycytidine Monophosphate; Deoxyguanine Nucleotides; Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Kinetics; Lysine; Molecular Sequence Data; Nucleoside-Phosphate Kinase; Phosphorylation; Pyridoxal Phosphate; Substrate Specificity; Thymidine Monophosphate | 1993 |
Bovine inositol monophosphatase. The identification of a histidine residue reactive to diethylpyrocarbonate.
Topics: Animals; Base Sequence; Binding Sites; Cattle; Diethyl Pyrocarbonate; Histidine; Lithium; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphoric Monoester Hydrolases; Recombinant Proteins | 1993 |
Modelling and modification of the binding site of endothelin and other receptors.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cattle; Cerebellum; Diethyl Pyrocarbonate; Endothelins; Histidine; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Rats; Receptors, Bombesin; Receptors, Dopamine; Receptors, Endothelin; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Serotonin; Sequence Analysis | 1993 |
Differential roles for three conserved histidine residues within the large subunit of carbamoyl phosphate synthetase.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Base Sequence; Bicarbonates; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Conserved Sequence; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Ornithine; Proton-Translocating ATPases | 1993 |
Diethylpyrocarbonate reactivity of Klebsiella aerogenes urease: effect of pH and active site ligands on the rate of inactivation.
Topics: Binding Sites; Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Kinetics; Klebsiella pneumoniae; Ligands; Urease | 1993 |
Site-directed mutagenesis and chemical modification of histidine residues on an alpha-class chick liver glutathione S-transferase CL 3-3. Histidines are not needed for the activity of the enzyme and diethylpyrocarbonate modifies both histidine and lysine
Topics: Amino Acid Sequence; Animals; Baculoviridae; Base Sequence; Chickens; Diethyl Pyrocarbonate; Glutathione Transferase; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Liver; Lysine; Molecular Sequence Data; Moths; Mutagenesis; Mutagenesis, Site-Directed; Peptide Mapping; Spectrophotometry; Trypsin | 1993 |
Folate transport in intestinal brush border membrane: involvement of essential histidine residue(s).
Topics: Animals; Binding Sites; Biological Transport; Carrier Proteins; Diethyl Pyrocarbonate; Folate Receptors, GPI-Anchored; Folic Acid; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Intestinal Mucosa; Intestines; Kinetics; Microvilli; Rabbits; Receptors, Cell Surface | 1993 |
Titration of histidine 62 in R67 dihydrofolate reductase is linked to a tetramer<-->two-dimer equilibrium.
Topics: Chromatography, Gel; Crystallization; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Iodides; Kinetics; Macromolecular Substances; Magnetic Resonance Spectroscopy; Molecular Weight; R Factors; Spectrometry, Fluorescence; Tetrahydrofolate Dehydrogenase; Ultracentrifugation | 1993 |
Kinetic evidence that His-711 of neutral endopeptidase 24.11 is involved in stabilization of the transition state.
Topics: Animals; Cell Line; Diethyl Pyrocarbonate; DNA; Enkephalin, Leucine-2-Alanine; Enzyme Stability; Histidine; Immunoblotting; Kinetics; Mutagenesis, Site-Directed; Neprilysin; Rabbits; Transfection | 1993 |
Histidine residues are essential for the surface binding and autoactivation of human coagulation factor XII.
Topics: Binding Sites; Circular Dichroism; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Factor VIIa; Factor XII; Histidine; Humans; Kinetics; Molecular Weight; Protein Conformation | 1993 |
Role of histidine residues in agonist and antagonist binding sites of A1 adenosine receptor.
Topics: Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Diethyl Pyrocarbonate; Guanylyl Imidodiphosphate; Histidine; Hydrogen-Ion Concentration; Kinetics; Phenylisopropyladenosine; Receptors, Purinergic; Swine; Xanthines | 1993 |
Bioluminescence of the Ca(2+)-binding photoprotein, aequorin, after histidine modification.
Topics: Aequorin; Calcium-Binding Proteins; Circular Dichroism; Diethyl Pyrocarbonate; Histidine; Luminescence; Mutagenesis, Site-Directed; Protein Structure, Secondary; Recombinant Proteins; Structure-Activity Relationship | 1993 |
His865 is the catalytically important histidyl residue of Syrian hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Catalysis; Conserved Sequence; Cricetinae; Diethyl Pyrocarbonate; DNA; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Mesocricetus; Molecular Sequence Data; Mutagenesis, Site-Directed | 1993 |
Prostaglandin H synthase. Inactivation of the enzyme in the course of catalysis is accompanied by fast and dramatic changes in protein structure.
Topics: Animals; Apoenzymes; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Diethyl Pyrocarbonate; Histidine; Kinetics; Male; Molecular Weight; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Trypsin | 1993 |
[Modification of RNA ligase histidine residues by diethylpyrocarbonate].
Topics: Diethyl Pyrocarbonate; Hexokinase; Histidine; RNA Ligase (ATP); Saccharomyces cerevisiae | 1993 |
Arginine residues of the globular regions of human C1q involved in the interaction with immunoglobulin G.
Topics: Amino Acid Sequence; Animals; Antigen-Antibody Complex; Arginine; Binding Sites, Antibody; Chromatography, High Pressure Liquid; Complement C1q; Cyclohexanones; Diethyl Pyrocarbonate; Histidine; Humans; Hydroxylamine; Hydroxylamines; Immunoglobulin G; Kinetics; Macromolecular Substances; Molecular Sequence Data; Peptide Fragments; Phenylglyoxal; Protein Conformation; Rabbits | 1993 |
Circular dichroism studies of diethyl pyrocarbonate-modified histidine in hen egg white lysozyme.
Topics: Amino Acid Sequence; Animals; Chickens; Circular Dichroism; Diethyl Pyrocarbonate; Female; Histidine; Kinetics; Muramidase; Protein Conformation; Spectrophotometry, Ultraviolet; Urea | 1993 |
Identification of the Zn2+ binding region in calreticulin.
Topics: Binding Sites; Calcium-Binding Proteins; Calreticulin; Chromatography, Agarose; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Factor Xa; Gene Expression Regulation, Bacterial; Histidine; Lectins; Peptide Fragments; Recombinant Fusion Proteins; Ribonucleoproteins; Zinc | 1995 |
The active site histidine of carnitine acyltransferases.
Topics: Binding Sites; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Diethyl Pyrocarbonate; Enzyme Inhibitors; Histidine; In Vitro Techniques; Kinetics | 1995 |
Substitution of two histidine residues in YadA protein of Yersinia enterocolitica abrogates collagen binding, cell adherence and mouse virulence.
Topics: Adhesins, Bacterial; Animals; Bacterial Adhesion; Base Sequence; Cell Division; Cloning, Molecular; Collagen; Diethyl Pyrocarbonate; DNA Primers; Extracellular Matrix Proteins; Fibronectins; Histidine; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenotype; Point Mutation; Protein Binding; Tumor Cells, Cultured; Virulence; Yersinia enterocolitica | 1995 |
Chemical modification of porcine kidney aminopeptidase P indicates the involvement of two critical histidine residues.
Topics: Aminopeptidases; Animals; Binding Sites; Bradykinin; Cell Membrane; Diethyl Pyrocarbonate; Enzyme Inhibitors; Histidine; Hydroxylamine; Hydroxylamines; Kidney; Kinetics; Oligopeptides; Peptides; Spectrophotometry, Ultraviolet; Swine | 1996 |
Identification of active site residues of chorismate mutase-prephenate dehydrogenase from Escherichia coli.
Topics: Binding Sites; Chorismate Mutase; Circular Dichroism; Diethyl Pyrocarbonate; Enzyme Inhibitors; Escherichia coli; Histidine; Kinetics; Ligands; Lysine; Prephenate Dehydrogenase; Spectrometry, Fluorescence; Trinitrobenzenesulfonic Acid | 1996 |
Identification of the active-site peptide of 2,3-dihydroxybenzoic acid decarboxylase from Aspergillus oryzae.
Topics: Amino Acid Sequence; Aspergillus oryzae; Benzoates; Binding Sites; Carboxy-Lyases; Catalysis; Cysteine; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Ethylmaleimide; Histidine; Hydrogen-Ion Concentration; Indoles; Kinetics; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1996 |
A single histidine is required for activity of cytochrome c peroxidase from Paracoccus denitrificans.
Topics: Amino Acid Sequence; Binding Sites; Carbon Radioisotopes; Chromatography, Gel; Conserved Sequence; Crystallography, X-Ray; Cyanides; Cytochrome-c Peroxidase; Diethyl Pyrocarbonate; Electron Spin Resonance Spectroscopy; Histidine; Kinetics; Mass Spectrometry; Oxidation-Reduction; Paracoccus denitrificans; Peptide Fragments; Protein Structure, Secondary; Spectrophotometry, Ultraviolet; Subtilisins; Trypsin | 1996 |
Heparinase I from Flavobacterium heparinum. Identification of a critical histidine residue essential for catalysis as probed by chemical modification and site-directed mutagenesis.
Topics: Amino Acid Sequence; Base Sequence; Diethyl Pyrocarbonate; DNA Primers; Flavobacterium; Heparin; Heparin Lyase; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligosaccharides; Point Mutation; Polymerase Chain Reaction; Polysaccharide-Lyases; Recombinant Proteins | 1996 |
Chemical modification of aminopeptidase P: identification of a critical histidyl residue.
Topics: Amino Acid Sequence; Aminopeptidases; Animals; Binding Sites; Bradykinin; Diethyl Pyrocarbonate; Enzyme Inhibitors; Histidine; In Vitro Techniques; Mice; Molecular Sequence Data; Molecular Structure; Oligopeptides; Swine | 1995 |
Rabbit muscle creatine kinase: consequences of the mutagenesis of conserved histidine residues.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Conserved Sequence; Creatine Kinase; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Escherichia coli; Histidine; Hot Temperature; Hydroxylamine; Hydroxylamines; Kinetics; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Rabbits; Recombinant Proteins; Sequence Homology, Amino Acid; Thermodynamics | 1996 |
Evidence for the presence of essential histidine and cysteine residues in platelet cGMP-inhibited phosphodiesterase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Monophosphate; Binding Sites; Blood Platelets; Catalysis; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Ethylmaleimide; Histidine; Humans; Kinetics; Phosphodiesterase Inhibitors | 1996 |
The reaction of phosphoglycerate mutase from Schizosaccharomyces pombe with diethylpyrocarbonate.
Topics: Binding Sites; Circular Dichroism; Diethyl Pyrocarbonate; Glutamine; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Mutagenesis, Site-Directed; Phosphoglycerate Mutase; Protein Conformation; Recombinant Proteins; Schizosaccharomyces; Spectrometry, Fluorescence | 1996 |
Key histidine residues in the nicotinic acetylcholine receptor.
Topics: Amino Acids; Animals; Bungarotoxins; Circular Dichroism; Diethyl Pyrocarbonate; Electric Fish; Electric Organ; Electrophoresis, Polyacrylamide Gel; Histidine; In Vitro Techniques; Iodine Radioisotopes; Ion Channels; Kinetics; Ligands; Nitrophenols; Protein Conformation; Receptors, Nicotinic; Spectrophotometry, Ultraviolet | 1996 |
Chemical modification of histidyl residues in D-amino acid oxidase from Rhodotorula gracilis.
Topics: Animals; Binding Sites; D-Amino-Acid Oxidase; Diethyl Pyrocarbonate; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration; Kidney; Kinetics; Logistic Models; Protons; Rhodotorula; Swine | 1995 |
Modeling of a mutation responsible for human 3-hydroxy-3-methylglutaryl-CoA lyase deficiency implicates histidine 233 as an active site residue.
Topics: Acyl Coenzyme A; Binding Sites; Diethyl Pyrocarbonate; Enzyme Inhibitors; Histidine; Humans; Hydrolysis; Metabolism, Inborn Errors; Oxo-Acid-Lyases; Point Mutation | 1996 |
Chemical modification of histidine residue of N-acyl-D-Glutamate amidohydrolase from Pseudomonas sp. 5f-1.
Topics: Amidohydrolases; Binding Sites; Carboxylic Acids; Catalysis; Diethyl Pyrocarbonate; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration; Pseudomonas | 1996 |
Histidine residues in rabbit liver microsomal cytochrome P-450 2B4 control electron transfer from NADPH-cytochrome P-450 reductase and cytochrome b5.
Topics: Acylation; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 Enzyme System; Cytochromes b5; Diethyl Pyrocarbonate; Electron Transport; Histidine; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Molecular Structure; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rabbits; Steroid Hydroxylases | 1996 |
Identification of the histidine residues involved in substrate recognition by a rat H+/peptide cotransporter, PEPT1.
Topics: Animals; Blotting, Western; Carrier Proteins; Ceftibuten; Cephalosporins; Cephradine; Diethyl Pyrocarbonate; Dipeptides; Histidine; Hydrogen-Ion Concentration; LLC-PK1 Cells; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Oocytes; Peptide Transporter 1; Plasmids; Rats; Recombinant Proteins; Swine; Symporters; Transfection; Xenopus | 1996 |
The role of conserved histidine residues in the pyridine nucleotide transhydrogenase of Escherichia coli.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Conserved Sequence; Diethyl Pyrocarbonate; Enzyme Inhibitors; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; NAD; NADP Transhydrogenases; Point Mutation; Protons; Substrate Specificity; Trypsin | 1996 |
Modification of tomato and Aspergillus niger pectinesterases with diethyl pyrocarbonate.
Topics: Aspergillus niger; Carboxylic Ester Hydrolases; Diethyl Pyrocarbonate; Histidine; Solanum lycopersicum; Spectrophotometry, Ultraviolet | 1996 |
Photodynamic crosslinking of proteins. II. Photocrosslinking of a model protein-ribonuclease A.
Topics: Animals; Cattle; Circular Dichroism; Cross-Linking Reagents; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Histidine; Lysine; Photochemistry; Ribonuclease, Pancreatic | 1996 |
Mechanism of aminoglycoside 3'-phosphotransferase type IIIa: His188 is not a phosphate-accepting residue.
Topics: Adenosine Triphosphate; Blotting, Western; Carbohydrate Sequence; Chemical Phenomena; Chemistry; Cloning, Molecular; Conserved Sequence; Diethyl Pyrocarbonate; Drug Resistance; Enterococcus; Histidine; Kanamycin Kinase; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligosaccharides; Phosphates; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Folding; Sequence Alignment; Staphylococcus | 1996 |
His-8 lowers the pKa of the essential Cys-12 residue of the ArsC arsenate reductase of plasmid R773.
Topics: Adenosine Triphosphatases; Arsenite Transporting ATPases; Codon; Cysteine; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Ion Pumps; Kinetics; Membrane Proteins; Multienzyme Complexes; Mutagenesis; Oxidation-Reduction; Plasmids; Structure-Activity Relationship | 1996 |
[Modification of the histidine in rat skeletal muscle deaminase by diethylpyrocarbonate].
Topics: AMP Deaminase; Animals; Binding Sites; Diethyl Pyrocarbonate; Histidine; Muscle, Skeletal; Rats | 1996 |
Chemical modification of an alpha 3-fucosyltransferase; definition of amino acid residues essential for enzyme activity.
Topics: Amino Acid Sequence; Cysteine; Diethyl Pyrocarbonate; Ethylmaleimide; Fucosyltransferases; Guanosine Diphosphate Fucose; Histidine; Humans; Molecular Sequence Data; Sequence Alignment | 1997 |
Identification of reactive conserved histidines in phosphoenolpyruvate carboxykinases from Escherichia coli and Saccharomyces cerevisiae.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Binding Sites; Conserved Sequence; Diethyl Pyrocarbonate; Enzyme Inhibitors; Escherichia coli; Histidine; Molecular Sequence Data; Peptide Fragments; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxykinase (GTP); Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Species Specificity; Substrate Specificity | 1997 |
Carbonyl reducing 17 beta-hydroxysteroid dehydrogenase from the filamentous fungus Cochliobolus lunatus.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Androstenedione; Ascomycota; Binding Sites; Binding, Competitive; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Hydroxysteroid Dehydrogenases; Immunoblotting; Kinetics; Lysine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Tetranitromethane; Trinitrobenzenesulfonic Acid; Tyrosine; Vitamin K | 1997 |
Identification of a histidine residue essential for enzymatic activity of group B streptococcal hyaluronate lyase.
Topics: Amino Acid Sequence; Diethyl Pyrocarbonate; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Polysaccharide-Lyases; Recombinant Proteins; Sequence Homology, Amino Acid; Streptococcus agalactiae | 1997 |
Influence of proton and essential histidyl residues on the transport kinetics of the H+/peptide cotransport systems in intestine (PEPT 1) and kidney (PEPT 2).
Topics: Animals; Biological Transport; Caco-2 Cells; Carrier Proteins; Cell Line; Cephalexin; Diethyl Pyrocarbonate; Dipeptides; Dose-Response Relationship, Drug; Histidine; Humans; Kidney Tubules, Proximal; Kinetics; Peptide Transporter 1; Protons; Rats; Symporters | 1997 |
2,3-Butanedione inactivates the [3H]nitrendipine binding sites, whereas diethylpyrocarbonate does not.
Topics: Animals; Arginine; Binding Sites; Brain; Calcium Channels; Diacetyl; Diethyl Pyrocarbonate; Histidine; Membranes; Nitrendipine; Protein Conformation; Rabbits; Radioligand Assay; Tritium | 1996 |
Roles of histidine-103 and tyrosine-235 in the function of the prolipoprotein diacylglyceryl transferase of Escherichia coli.
Topics: Amino Acid Sequence; Conserved Sequence; Diethyl Pyrocarbonate; Escherichia coli; Genetic Complementation Test; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phylogeny; Point Mutation; Recombinant Proteins; Structure-Activity Relationship; Transferases; Tyrosine | 1997 |
Evidence supporting a role for histidine-235 in cation binding to human 3-hydroxy-3-methyglutaryl-CoA lyase.
Topics: Alanine; Aspartic Acid; Binding Sites; Catalysis; Cations, Divalent; Diethyl Pyrocarbonate; Electron Spin Resonance Spectroscopy; Histidine; Humans; Kinetics; Magnesium; Manganese; Mutagenesis, Site-Directed; Oxo-Acid-Lyases; Polymerase Chain Reaction; Structure-Activity Relationship | 1997 |
Evidence for the essential histidine at the NADPH binding site of enoyl-CoA reductase domain of pigeon liver fatty acid synthetase.
Topics: Animals; Binding Sites; Columbidae; Diethyl Pyrocarbonate; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Activation; Fatty Acid Synthases; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Liver; NADP; Oxidoreductases; Protein Structure, Tertiary; Substrate Specificity; Time Factors | 1997 |
Role of histidyl residues in the binding of ligands to the porcine N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Diethyl Pyrocarbonate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Histidine; Ionophores; Kainic Acid; Ligands; N-Methylaspartate; Piperazines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Swine; Synaptic Membranes; Tritium | 1997 |
Histidine modification of human serum butyrylcholinesterase.
Topics: Binding Sites; Butyrylcholinesterase; Catalysis; Cholinesterase Inhibitors; Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Humans; Kinetics; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone | 1997 |
Partial identification of the Zn2+-binding sites in factor XII and its activation derivatives.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Diethyl Pyrocarbonate; Factor XII; Factor XIIa; Guinea Pigs; Histidine; Humans; Molecular Sequence Data; Sequence Alignment; Sequence Homology, Amino Acid; Zinc | 1997 |
Diethylpyrocarbonate, a histidine selective reagent, causes structural alteration of rat ovarian LH/hCG receptor.
Topics: Animals; Cell Membrane; Cells, Cultured; Diethyl Pyrocarbonate; Female; Fluorescence Polarization; Histidine; Ovary; Protein Binding; Rats; Rats, Wistar; Receptors, LH; Structure-Activity Relationship; Thermodynamics | 1997 |
Vitamin K2 (menaquinone) biosynthesis in Escherichia coli: evidence for the presence of an essential histidine residue in o-succinylbenzoyl coenzyme A synthetase.
Topics: Adenosine Triphosphate; Binding Sites; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Magnesium; Mutagenesis, Site-Directed; Phenylbutyrates; Spectrophotometry, Ultraviolet; Succinate-CoA Ligases; Vitamin K | 1997 |
Identification of the prooxidant site of human ceruloplasmin: a model for oxidative damage by copper bound to protein surfaces.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Carbon Radioisotopes; Ceruloplasmin; Copper; COS Cells; Diethyl Pyrocarbonate; Histidine; Humans; Lipoproteins, LDL; Models, Molecular; Mutagenesis, Site-Directed; Oxidative Stress; Protein Conformation; Reactive Oxygen Species; Recombinant Proteins; Transfection | 1997 |
Evidence for the essential histidine residues in geranylgeranyl transferase type I from bovine testis.
Topics: Alkyl and Aryl Transferases; Animals; Binding Sites; Cattle; Chromatography; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Iodoacetates; Iodoacetic Acid; Kinetics; Male; Testis | 1997 |
Identification of essential histidine residues in UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T1.
Topics: Animals; Binding Sites; Cattle; Diethyl Pyrocarbonate; Enzyme Activation; Glycosylation; Histidine; Isoenzymes; Kinetics; N-Acetylgalactosaminyltransferases; Recombinant Proteins | 1997 |
Modification of histidine 5 in sarcoplasmic reticulum Ca2+-ATPase by diethyl pyrocarbonate causes strong inhibition of formation of the phosphoenzyme intermediate from inorganic phosphate.
Topics: Animals; Calcium-Transporting ATPases; Diethyl Pyrocarbonate; Enzyme Inhibitors; Fluorides; Histidine; Magnesium; Phosphates; Protein Conformation; Rabbits; Sarcoplasmic Reticulum; Vanadates | 1997 |
Copper ions promote peroxidation of low density lipoprotein lipid by binding to histidine residues of apolipoprotein B100, but they are reduced at other sites on LDL.
Topics: Antioxidants; Apolipoprotein B-100; Apolipoproteins B; Binding Sites; Copper; Diethyl Pyrocarbonate; Histidine; Humans; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Oxidants; Oxidation-Reduction | 1997 |
A functional role for histidyl residues of the UDP-glucuronic acid carrier in rat liver endoplasmic reticulum membranes.
Topics: Acetophenones; Animals; Benzenesulfonates; Carrier Proteins; Cross-Linking Reagents; Diethyl Pyrocarbonate; Endoplasmic Reticulum; Histidine; Hydrogen-Ion Concentration; Intracellular Membranes; Kinetics; Male; Microsomes, Liver; Nitro Compounds; Photoaffinity Labels; Rats; Rats, Sprague-Dawley; Uridine Diphosphate Glucuronic Acid; Uridine Diphosphate Sugars | 1998 |
Site directed mutagenesis of histidine residues in anthrax toxin lethal factor binding domain reduces toxicity.
Topics: Animals; Anthrax; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Binding, Competitive; CHO Cells; Cricetinae; Diethyl Pyrocarbonate; Histidine; Mice; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins | 1997 |
Interaction of beta-lactam antibiotics with histidine residue of rat H+/peptide cotransporters, PEPT1 and PEPT2.
Topics: Animals; Anti-Bacterial Agents; Binding Sites; Carrier Proteins; Cell Line; Cephalosporins; Diethyl Pyrocarbonate; Dipeptides; Histidine; Kidney; Peptide Transporter 1; Rats; Symporters; Transfection | 1998 |
Diethyl pyrocarbonate (DEPC) inhibits CO2 chemosensitivity in Helix aspersa.
Topics: Ammonium Chloride; Animals; Carbon Dioxide; Chemoreceptor Cells; Diethyl Pyrocarbonate; Helix, Snails; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Hypercapnia; Hypoxia; In Vitro Techniques; Nitroprusside; Respiration | 1998 |
Determination of diethylpyrocarbonate-modified amino acid residues in alpha 1-acid glycoprotein by high-performance liquid chromatography electrospray ionization-mass spectrometry and matrix-assisted laser desorption/ionization time-of-flight-mass spectro
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Chymotrypsin; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Orosomucoid; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Trypsin; Tyrosine | 1998 |
Functional evidence for a pH sensor of erythrocyte K-Cl cotransport through inhibition by internal protons and diethylpyrocarbonate.
Topics: Animals; Carrier Proteins; Cell Size; Chlorides; Diethyl Pyrocarbonate; Erythrocytes; Histidine; Hydrogen-Ion Concentration; Ion Transport; K Cl- Cotransporters; Magnesium; Osmolar Concentration; Ouabain; Potassium; Protons; Rubidium; Sheep; Symporters | 1998 |
Heparinase II from Flavobacterium heparinum. Role of histidine residues in enzymatic activity as probed by chemical modification and site-directed mutagenesis.
Topics: Binding Sites; Diethyl Pyrocarbonate; Enzyme Activation; Flavobacterium; Heparin; Heparin Lyase; Heparitin Sulfate; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Molecular Probes; Mutagenesis, Site-Directed | 1998 |
Stereospecificity and catalytic function of histidine residues in 4a-hydroxy-tetrahydropterin dehydratase/DCoH.
Topics: Alanine; Animals; Biopterins; Buffers; Catalysis; Cattle; Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Hydro-Lyases; Imidazoles; Liver; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Recombinant Proteins; Sodium Acetate; Stereoisomerism; Substrate Specificity | 1998 |
Potential role for imidazole in the rhythmic respiratory activity of the in vitro neonatal rat brainstem.
Topics: Animals; Animals, Newborn; Brain Stem; Diethyl Pyrocarbonate; Histidine; Hydroxylamine; Imidazoles; In Vitro Techniques; Medulla Oblongata; Microinjections; Periodicity; Rats; Rats, Sprague-Dawley; Respiration; Spinal Cord | 1998 |
In the uncoupling protein (UCP-1) His-214 is involved in the regulation of purine nucleoside triphosphate but not diphosphate binding.
Topics: Adipose Tissue, Brown; Amino Acid Substitution; Animals; Binding Sites; Carrier Proteins; Cloning, Molecular; Cricetinae; Diethyl Pyrocarbonate; Guanosine Diphosphate; Guanosine Triphosphate; Histidine; Hydrogen-Ion Concentration; Ion Channels; Kinetics; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Models, Molecular; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Protons; Recombinant Proteins; Substrate Specificity; Uncoupling Protein 1 | 1998 |
Chemical modification of histidine residues in human 'electron transferring flavoprotein' (ETF).
Topics: Amino Acid Sequence; Animals; Diethyl Pyrocarbonate; Electron-Transferring Flavoproteins; Flavoproteins; Histidine; Humans; Kinetics; Macromolecular Substances; Paracoccus denitrificans; Rats; Veillonellaceae | 1998 |
Effects of L-histidine and its structural analogues on human N-myristoyltransferase activity and importance of EEVEH amino acid sequence for enzyme activity.
Topics: Acyltransferases; Amino Acid Sequence; Binding Sites; Catalysis; Cyclic AMP-Dependent Protein Kinases; Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Histidinol; Humans; Mutagenesis, Site-Directed; Peptide Fragments; Protein Processing, Post-Translational; Sequence Deletion | 1998 |
Galactose mutarotase: purification, characterization, and investigations of two important histidine residues.
Topics: Conserved Sequence; Diethyl Pyrocarbonate; Escherichia coli; Galactose; Histidine; Hydrolysis; Kinetics; Metals; Mutagenesis, Site-Directed; UDPglucose 4-Epimerase | 1998 |
Localization of critical histidyl residues required for vinblastine-induced tubulin polymerization and for microtubule assembly.
Topics: Animals; Diethyl Pyrocarbonate; Histidine; Hydroxylamine; Microtubules; Peptide Mapping; Polymers; Rats; Tubulin; Vinblastine | 1998 |
Analysis of essential histidine residues of maize branching enzymes by chemical modification and site-directed mutagenesis.
Topics: 1,4-alpha-Glucan Branching Enzyme; Amino Acid Sequence; Conserved Sequence; Diethyl Pyrocarbonate; DNA Primers; Escherichia coli; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Zea mays | 1998 |
Influence of chemical modification of cysteine and histidine side chains upon subunit reassembly of alpha crystallin.
Topics: Chromatography, Gel; Circular Dichroism; Crystallins; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Histidine; Protein Conformation; Protein Folding; Structure-Activity Relationship | 1998 |
Essential histidyl residues at the active site(s) of sucrose-phosphate synthase from Prosopis juliflora.
Topics: Amino Acid Sequence; Binding Sites; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Dithiothreitol; Enzyme Activation; Enzyme Inhibitors; Fructosephosphates; Glucosyltransferases; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Plant Proteins; Plants; Pyridoxal Phosphate; Rose Bengal; Spectrophotometry; Uridine Diphosphate Glucose | 1998 |
Study on splitting of sucrose glycoside bonds by beta-fructosidase of Aspergillus niger VKM F-801.
Topics: Aspergillus niger; beta-Fructofuranosidase; Catalytic Domain; Diethyl Pyrocarbonate; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Oxidation-Reduction; Photochemistry; Sucrose | 1998 |
Involvement of essential cysteine and histidine residues in the activity of isolated glutaminase from tumour cells.
Topics: Animals; Binding Sites; Carcinoma, Ehrlich Tumor; Cysteine; Diethyl Pyrocarbonate; Enzyme Inhibitors; Ethylmaleimide; Glutaminase; Histidine; Hydrogen-Ion Concentration; Intracellular Membranes | 1998 |
The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating.
Topics: Anions; Binding, Competitive; Cations; Cell Line; Cell Membrane; Diethyl Pyrocarbonate; Electrophysiology; Glutamine; Glycine; Histidine; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Ion Channels; Membrane Potentials; Mutation, Missense; Patch-Clamp Techniques; Radioligand Assay; Receptors, Glycine; Recombinant Fusion Proteins; Reflex, Startle; Strychnine; Taurine; Tritium; Zinc | 1999 |
Identification of residues essential for human paraoxonase (PON1) arylesterase/organophosphatase activities.
Topics: Amino Acids; Animals; Aryldialkylphosphatase; Aspartic Acid; Binding Sites; Bromosuccinimide; Calcium Radioisotopes; Cell Line; Dicyclohexylcarbodiimide; Diethyl Pyrocarbonate; Enzyme Activation; Enzyme Inhibitors; Esterases; Glutamic Acid; Glycosylation; Histidine; Humans; Indicators and Reagents; Kidney; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Rabbits; Recombinant Proteins; Spectrometry, Fluorescence; Terbium; Tryptophan | 1999 |
Kinetic and mutagenic evidence for the role of histidine residues in the Lycopersicon esculentum 1-aminocyclopropane-1-carboxylic acid oxidase.
Topics: Amino Acids; Amino Acids, Cyclic; Circular Dichroism; Cloning, Molecular; Deoxycholic Acid; Diethyl Pyrocarbonate; Ethylenes; Guanidine; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Imidazoles; Inclusion Bodies; Kinetics; Mutagenesis, Site-Directed; Recombinant Proteins; Solanum lycopersicum; Spectrometry, Fluorescence; Time Factors | 1999 |
Histidine mapping of serine protease: a synergic study by IMAC and molecular modelling.
Topics: Animals; Aprotinin; Catalytic Domain; Cattle; Chromatography, Affinity; Diethyl Pyrocarbonate; Histidine; Models, Molecular; Serine Endopeptidases; Subtilisins; Swine; Trypsin | 1998 |
Enzymatical properties of psychrophilic phosphatase I.
Topics: Amino Acid Sequence; Catalytic Domain; Cold Temperature; Diethyl Pyrocarbonate; Enzyme Inhibitors; Gram-Negative Facultatively Anaerobic Rods; Histidine; Kinetics; Molecular Sequence Data; Phosphoric Monoester Hydrolases; Protein Tyrosine Phosphatases; Substrate Specificity | 1999 |
Identification of three cysteines as targets for the Zn2+ blockade of the human skeletal muscle chloride channel.
Topics: Cell Line; Chloride Channels; Cysteine; Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen-Ion Concentration; Muscle Proteins; Muscle, Skeletal; Mutagenesis, Site-Directed; Zinc | 1999 |
Chemical modification of NADP-isocitrate dehydrogenase from Cephalosporium acremonium evidence of essential histidine and lysine groups at the active site.
Topics: Acremonium; Binding Sites; Diethyl Pyrocarbonate; Enzyme Inhibitors; Enzyme Reactivators; Histidine; Hydroxylamine; Isocitrate Dehydrogenase; Kinetics; Lysine; Pyridoxal Phosphate | 1999 |
Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor.
Topics: Animals; Diethyl Pyrocarbonate; Female; Histidine; Mutation; Oocytes; Patch-Clamp Techniques; Protein Isoforms; Receptors, N-Methyl-D-Aspartate; Xenopus laevis; Zinc | 1999 |
Mechanisms of inhibitory effects of zinc and cadmium ions on agonist binding to adenosine A1 receptors in rat brain.
Topics: Adenosine; Amino Acids, Sulfur; Animals; Binding, Competitive; Brain; Cadmium; Culture Media; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Dithiothreitol; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Sulfhydryl Compounds; Sulfhydryl Reagents; Tritium; Zinc | 1999 |
Evidence that several conserved histidine residues are required for hydrolytic activity of human paraoxonase/arylesterase.
Topics: Amino Acid Sequence; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Cells, Cultured; Conserved Sequence; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Esterases; Histidine; Humans; Hydrolysis; Kidney; Kinetics; Mutagenesis, Site-Directed; Recombinant Proteins; Structure-Activity Relationship; Transfection | 1999 |
Active site determination of yeast geranylgeranyl protein transferase type I expressed in Escherichia coli.
Topics: Alkyl and Aryl Transferases; Catalytic Domain; Chitin Synthase; Diethyl Pyrocarbonate; Escherichia coli; Fungal Proteins; Histidine; Models, Chemical; Mutagenesis, Site-Directed; Phenylglyoxal; Polyisoprenyl Phosphates; Protein Prenylation; Recombinant Proteins; Saccharomyces cerevisiae Proteins; Substrate Specificity; Transferases; Yeasts | 1999 |
Chemical modification and site-directed mutagenesis of conserved HXXH and PP-loop motif arginines and histidines in the murine bifunctional ATP sulfurylase/adenosine 5'-phosphosulfate kinase.
Topics: Amino Acid Sequence; Animals; Arginine; Chondrosarcoma; Conserved Sequence; Diethyl Pyrocarbonate; Histidine; Kinetics; Mice; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Phenylglyoxal; Sequence Alignment; Spectrophotometry; Sulfate Adenylyltransferase | 1999 |
Mechanism for the effects of extracellular acidification on HERG-channel function.
Topics: Acids; Animals; Binding Sites; Cation Transport Proteins; Diethyl Pyrocarbonate; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Extracellular Space; Histidine; Humans; Hydrogen; Hydrogen-Ion Concentration; Models, Biological; Oocytes; Potassium Channels; Potassium Channels, Voltage-Gated; Protons; Trans-Activators; Transcriptional Regulator ERG; Xenopus laevis | 1999 |
Identification of an inhibitory Zn2+ binding site on the human glycine receptor alpha1 subunit.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Diethyl Pyrocarbonate; Electrophysiology; Extracellular Matrix; Genetic Vectors; Glycine; Histidine; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Receptors, Glycine; Zinc | 1999 |
Evidence that histidine-163 is critical for catalytic activity, but not for substrate binding to Escherichia coli agmatinase.
Topics: Catalysis; Diethyl Pyrocarbonate; Enzyme Inhibitors; Escherichia coli; Histidine; Kinetics; Mutagenesis, Site-Directed; Rose Bengal; Substrate Specificity; Ureohydrolases | 1999 |
Chemical modification and site-directed mutagenesis of human liver arginase: evidence that the imidazole group of histidine-141 is not involved in substrate binding.
Topics: Arginase; Arginine; Catalytic Domain; Diethyl Pyrocarbonate; Histidine; Humans; Light; Liver; Lysine; Mutagenesis, Site-Directed; Ornithine; Rose Bengal | 1999 |
Proton transfer from histidine 244 may facilitate the 1,2 rearrangement reaction in coenzyme B(12)-dependent methylmalonyl-CoA mutase.
Topics: Binding Sites; Cobamides; Diethyl Pyrocarbonate; Free Radicals; Histidine; Hydrogen-Ion Concentration; Kinetics; Methylmalonyl-CoA Mutase; Mutation; Protons; Quantum Theory; Recombinant Proteins; Spectrophotometry | 1999 |
Histidine modification and mutagenesis point to the involvement of a large conformational change in the mechanism of action of phage lambda lysozyme.
Topics: Bacteriophage lambda; Diethyl Pyrocarbonate; Enzyme Activation; Enzyme Stability; Histidine; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Protein Conformation; Viral Proteins | 1999 |
Identification of essential histidine residues in 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase: analysis by chemical modification with diethyl pyrocarbonate and site-directed mutagenesis.
Topics: Aldehyde-Lyases; Amino Acid Sequence; Binding Sites; Catalysis; Diethyl Pyrocarbonate; Enzyme Activation; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Substrate Specificity | 1999 |
Histidine modifying agents abolish pyruvate dehydrogenase kinase activity.
Topics: Arabidopsis; Diethyl Pyrocarbonate; Histidine; Histidine Kinase; Organoplatinum Compounds; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase (Lipoamide); Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Recombinant Fusion Proteins | 2000 |
A spectroscopic study of the reaction of NAMI, a novel ruthenium(III)anti-neoplastic complex, with bovine serum albumin.
Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Cattle; Chlorides; Circular Dichroism; Dialysis; Diethyl Pyrocarbonate; Dimethyl Sulfoxide; Histidine; Hydrolysis; Ligands; Organometallic Compounds; Oxidation-Reduction; Protein Binding; Ruthenium; Ruthenium Compounds; Serum Albumin, Bovine; Spectrophotometry, Atomic | 2000 |
A critical histidine in the vesicular acetylcholine transporter.
Topics: Animals; Binding Sites; Carrier Proteins; Cysteine; Diethyl Pyrocarbonate; Electric Organ; Histidine; Hydrogen-Ion Concentration; Membrane Transport Proteins; Neuromuscular Depolarizing Agents; Piperidines; Protons; Synaptic Vesicles; Torpedo; Tritium; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 2000 |
Enthalpy and enzyme activity of modified histidine residues of adenosine deaminase and diethyl pyrocarbonate complexes.
Topics: Adenosine Deaminase; Animals; Cattle; Diethyl Pyrocarbonate; Histidine; Spectrophotometry, Ultraviolet | 2000 |
Role of conserved histidine residues in D-aminoacylase from Alcaligenes xylosoxydans subsp. xylosoxydans A-6.
Topics: Alcaligenes; Amidohydrolases; Catalysis; Circular Dichroism; Cobalt; Diethyl Pyrocarbonate; Histidine; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Structure-Activity Relationship; Zinc | 2000 |
Diethyl pyrocarbonate inactivates CD39/ecto-ATPDase by modifying His-59.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Cell Line, Transformed; Diethyl Pyrocarbonate; Enzyme Inhibitors; Histidine; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Rats; Sequence Homology, Amino Acid | 2000 |
Functional roles of histidine and tyrosine residues in the H(+)-peptide transporter PepT1.
Topics: Amino Acid Substitution; Animals; Base Sequence; Biological Transport; Carrier Proteins; Diethyl Pyrocarbonate; Dipeptides; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Mutation; Oocytes; Peptide Transporter 1; Protons; Rabbits; Substrate Specificity; Symporters; Tyrosine; Xenopus laevis | 2000 |
The role of histidines in the acetate kinase from Methanosarcina thermophila.
Topics: Acetate Kinase; Binding Sites; Diethyl Pyrocarbonate; Histidine; Kinetics; Methanosarcina; Phosphorylation; Structure-Activity Relationship | 2000 |
Evidence for catalytic cysteine-histidine dyad in chalcone synthase.
Topics: Acyltransferases; Amino Acid Substitution; Binding Sites; Catalysis; Cysteine; Diethyl Pyrocarbonate; Enzyme Inhibitors; Escherichia coli; Flavanones; Flavonoids; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Malonyl Coenzyme A; Mutagenesis, Site-Directed; Plants; Recombinant Fusion Proteins; Resveratrol; Stilbenes | 2000 |
Subunit-dependent modulation of neuronal nicotinic receptors by zinc.
Topics: Acetylcholine; Animals; Cadmium; Cells, Cultured; Diethyl Pyrocarbonate; Dimerization; Dose-Response Relationship, Drug; Drug Synergism; Histidine; Hydrogen-Ion Concentration; Nickel; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Protein Subunits; Rats; Receptors, Nicotinic; Transfection; Xenopus; Zinc | 2001 |
Heparin-binding histidine and lysine residues of rat selenoprotein P.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbon Radioisotopes; Chromatography, Affinity; Chromatography, High Pressure Liquid; Diethyl Pyrocarbonate; Heparin; Histidine; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Peptide Fragments; Proteins; Rats; Selenoprotein P; Selenoproteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2001 |
Evidence for an essential histidine residue in the ascorbate-binding site of cytochrome b561.
Topics: Animals; Ascorbic Acid; Binding Sites; Cattle; Chromaffin Granules; Cytochrome b Group; Diethyl Pyrocarbonate; Enzyme Inhibitors; Formates; Histidine; Hydrogen-Ion Concentration; Imidazoles; Intracellular Membranes; Kinetics; Oxidation-Reduction; Protons | 2001 |
Ascorbate inhibits the carbethoxylation of two histidyl and one tyrosyl residues indispensable for the transmembrane electron transfer reaction of cytochrome b561.
Topics: Animals; Anions; Ascorbic Acid; Cattle; Cytochrome b Group; Diethyl Pyrocarbonate; Electron Transport; Enzyme Inhibitors; Histidine; Hydrolysis; Membrane Proteins; Oxidation-Reduction; Potentiometry; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin; Tyrosine | 2001 |
Methane monooxygenase component B mutants alter the kinetics of steps throughout the catalytic cycle.
Topics: Amino Acid Sequence; Amino Acid Substitution; Catalysis; Diethyl Pyrocarbonate; Enzyme Activation; Furans; Histidine; Kinetics; Methane; Methylosinus trichosporium; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygenases; Peptide Fragments; Recombinant Proteins; Substrate Specificity | 2001 |
An essential role of active site arginine residue in iodide binding and histidine residue in electron transfer for iodide oxidation by horseradish peroxidase.
Topics: Arginine; Binding Sites; Carbon Radioisotopes; Circular Dichroism; Cyclohexanones; Diacetyl; Diethyl Pyrocarbonate; Electron Transport; Histidine; Horseradish Peroxidase; Hydroxamic Acids; Iodides; Kinetics; Oxidation-Reduction; Phenylglyoxal; Spectrophotometry; Thermodynamics | 2001 |
The importance of histidine residues in human ecto-nucleoside triphosphate diphosphohydrolase-3 as determined by site-directed mutagenesis.
Topics: Animals; Antigens, CD; Apyrase; Binding Sites; Cell Membrane; Conserved Sequence; COS Cells; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Mutagenesis, Site-Directed; Mutation; Pyrophosphatases | 2001 |
Probing the binding site of 800-nm bacteriochlorophyll in the membrane-linked LH2 protein of Rhodobacter capsulatus by local unfolding and chemical modification: evidence for the involvement of a betaHis20 residue.
Topics: Bacteriochlorophylls; Binding Sites; Cell Membrane; Circular Dichroism; Diethyl Pyrocarbonate; Enzyme Inhibitors; Guanidine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Light-Harvesting Protein Complexes; Models, Chemical; Photosynthetic Reaction Center Complex Proteins; Protein Binding; Protein Folding; Protein Structure, Tertiary; Rhodobacter capsulatus; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Urea | 2001 |
Conformation and polarity of the active site of xylanase I from Thermomonospora sp. as deduced by fluorescent chemoaffinity labeling. Site and significance of a histidine residue.
Topics: Actinomycetales; Affinity Labels; Amino Acids; Binding Sites; Circular Dichroism; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Enzyme Activation; Ethylmaleimide; Histidine; Hydroxymercuribenzoates; Indicators and Reagents; Kinetics; Lysine; Models, Chemical; o-Phthalaldehyde; Protease Inhibitors; Protein Binding; Protein Conformation; Sequence Analysis, Protein; Spectrometry, Fluorescence; Sulfhydryl Reagents; Time Factors; Trinitrobenzenesulfonic Acid; Urea; Xylan Endo-1,3-beta-Xylosidase; Xylosidases | 2001 |
Enzymatic active site of caspase-activated DNase (CAD) and its inhibition by inhibitor of CAD.
Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Caspases; Cell Line; Deoxyribonucleases; Diethyl Pyrocarbonate; DNA Fragmentation; Dose-Response Relationship, Drug; Histidine; Imidazoles; Insecta; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Biosynthesis; Recombinant Proteins; Sequence Homology, Amino Acid; Time Factors | 2001 |
Conformational change in the vinculin C-terminal depends on a critical histidine residue (His-906).
Topics: Alanine; Amino Acid Substitution; Binding Sites; Chromatography, Gel; Circular Dichroism; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Phospholipids; Protein Conformation; Recombinant Proteins; Spectrophotometry, Ultraviolet; Vinculin | 2001 |
Inhibition of plant vacuolar H(+)-ATPase by diethylpyrocarbonate.
Topics: Adenosine Triphosphate; Dicyclohexylcarbodiimide; Diethyl Pyrocarbonate; Enzyme Activation; Enzyme Inhibitors; Histidine; Kinetics; Plants; Proton-Translocating ATPases; Protons; Spectrophotometry, Ultraviolet; Substrate Specificity; Vacuolar Proton-Translocating ATPases | 2001 |
Slowing of ERG current deactivation in NG108-15 cells by the histidine-specific reagent diethylpyrocarbonate.
Topics: Animals; Clone Cells; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Histidine; Membrane Potentials; Mice; Neuroblastoma; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Tumor Cells, Cultured | 2001 |
Functional residues on the enzyme active site of glyoxalase I from bovine brain.
Topics: Animals; Arginine; Binding Sites; Brain; Cattle; Diethyl Pyrocarbonate; Dimerization; Epoxy Compounds; Erythrocytes; Histidine; Humans; Kinetics; Lactoylglutathione Lyase; Molecular Weight; Phenylglyoxal; Spectrometry, Fluorescence; Structure-Activity Relationship; Titrimetry; Tryptophan; Yeasts | 2001 |
Inhibition of the neutrophil NADPH oxidase and associated H+ channel by diethyl pyrocarbonate (DEPC), a histidine-modifying agent: evidence for at least two target sites.
Topics: Cytochrome b Group; Diethyl Pyrocarbonate; Heme; Histidine; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Ion Channels; Ion Transport; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Protons; Subcellular Fractions; Superoxides; Tetrazolium Salts | 2001 |
Evidence for essential histidines in human pituitary glutaminyl cyclase.
Topics: Amino Acid Sequence; Aminoacyltransferases; Aminopeptidases; Conserved Sequence; Diethyl Pyrocarbonate; Histidine; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Pituitary Gland; Sequence Homology, Amino Acid | 2001 |
A common inhibitory binding site for zinc and odorants at the voltage-gated K(+) channel of rat olfactory receptor neurons.
Topics: 4-Chloromercuribenzenesulfonate; Acetophenones; Animals; Binding Sites; Carbon Monoxide; Cells, Cultured; Cyclohexenes; Cysteine; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Histidine; Limonene; Membrane Potentials; Mesylates; Neural Inhibition; Nitric Oxide; Olfactory Receptor Neurons; Patch-Clamp Techniques; Pentanols; Potassium; Potassium Channels; Rats; Receptors, Odorant; Smell; Sulfhydryl Reagents; Terpenes; Zinc | 2001 |
An essential histidine residue in GTP binding domain of bovine brain glutamate dehydrogenase isoproteins.
Topics: Adenosine Triphosphate; Animals; Brain; Cattle; Chromatography, Affinity; Diethyl Pyrocarbonate; Glutamate Dehydrogenase; GTP-Binding Proteins; Guanosine Triphosphate; Histidine; Isoenzymes; Protein Structure, Tertiary | 2001 |
Identification of functionally relevant histidine residues in the apoptotic nuclease CAD.
Topics: Amino Acid Sequence; Animals; Apoptosis; Catalysis; Chromatography, Gel; Circular Dichroism; Deoxyribonucleases; Diethyl Pyrocarbonate; DNA; Glutathione Transferase; Histidine; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid | 2001 |
Possible involvement of a single histidine residue in the P-type Na+-ATPase of a facultatively anaerobic alkaliphile, Exiguobacterium aurantiacum.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine Triphosphatases; Bacteria, Anaerobic; Cation Transport Proteins; Diethyl Pyrocarbonate; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration | 2001 |
Structure-function analysis of the ArsA ATPase: contribution of histidine residues.
Topics: Antimony; Arsenite Transporting ATPases; Arsenites; Base Sequence; Catalytic Domain; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Ion Pumps; Multienzyme Complexes; Mutagenesis, Site-Directed; Protein Conformation; Sequence Analysis, DNA; Structure-Activity Relationship | 2001 |
Identification of histidine residues at the active site of Megalobatrachus japonicus alkaline phosphatase by chemical modification.
Topics: Alkaline Phosphatase; Amphibians; Animals; Binding Sites; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Spectrophotometry, Ultraviolet; Substrate Specificity | 2002 |
Diethylpyrocarbonate inhibition of vacuolar H+-pyrophosphatase possibly involves a histidine residue.
Topics: Diethyl Pyrocarbonate; Enzyme Inhibitors; Fabaceae; Histidine; Hydroxylamine; Inorganic Pyrophosphatase; Ligands; Plant Proteins; Protons; Pyrophosphatases; Regression Analysis; Vacuoles | 2002 |
Differential interactions of estrogens and antiestrogens at the 17 beta-hydroxyl or counterpart hydroxyl with histidine 524 of the human estrogen receptor alpha.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; COS Cells; Diethyl Pyrocarbonate; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Estrogens; Histidine; Humans; Hydroxyl Radical; Ligands; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen | 2002 |
Interaction of adenosine deaminase with inhibitors. Chemical modification by diethyl pyrocarbonate.
Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Binding Sites; Cattle; Diethyl Pyrocarbonate; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration; Kinetics; Spleen; Substrate Specificity | 2002 |
Insights into the interaction of human liver arginase with tightly and weakly bound manganese ions by chemical modification and site-directed mutagenesis studies.
Topics: Arginase; Arginine; Diethyl Pyrocarbonate; Enzyme Activation; Histidine; Humans; Hydroxylamine; Liver; Manganese; Mutagenesis, Site-Directed; Point Mutation | 2002 |
Probing the role of active site histidine residues in the catalytic activity of lacrimal gland peroxidase.
Topics: Animals; Binding Sites; Catalysis; Circular Dichroism; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Heme; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Kinetics; Lacrimal Apparatus; Models, Chemical; Peroxidase; Protein Binding; Protein Structure, Secondary; Sheep; Substrate Specificity; Temperature; Time Factors; Ultraviolet Rays | 2002 |
Contribution of histidine residues to oligomerization of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin.
Topics: Bacterial Toxins; Clostridium perfringens; Diethyl Pyrocarbonate; Hemolysin Proteins; Histidine; Liposomes; Macromolecular Substances; Spectrometry, Fluorescence; Tryptophan | 1999 |
The PrP-like protein Doppel binds copper.
Topics: Animals; Binding Sites; Binding, Competitive; Blotting, Western; Carbon; Chymotrypsin; Circular Dichroism; Copper; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Free Radicals; GPI-Linked Proteins; Histidine; Kinetics; Mice; Nitrogen; Peptides; Prions; Protein Binding; Proteins; PrPC Proteins; Recombinant Proteins; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 2003 |
Chemical modification of microcin J25 with diethylpyrocarbonate and carbodiimide: evidence for essential histidyl and carboxyl residues.
Topics: Anti-Bacterial Agents; Bacteriocins; Binding Sites; Carbodiimides; Chromatography, High Pressure Liquid; Diethyl Pyrocarbonate; Enzyme Inhibitors; Escherichia coli; Histidine; Microbial Sensitivity Tests; Peptides; Plasmids; Salmonella; Topoisomerase II Inhibitors | 2003 |
Evidence for essential histidine and dicarboxylic amino-acid residues in the active site of UDP-glucose : solasodine glucosyltransferase from eggplant leaves.
Topics: Amino Acids, Dicarboxylic; Binding Sites; Diethyl Pyrocarbonate; Enzyme Inhibitors; Glucosyltransferases; Glycosylation; Histidine; Isoxazoles; Molecular Probes; Plant Leaves; Solanaceous Alkaloids; Solanum melongena; Spirostans; Tritium; Uridine Diphosphate Glucose | 2003 |
Identification of essential histidines in cyclodextrin glycosyltransferase isoform 1 from Paenibacillus sp. A11.
Topics: Amino Acid Sequence; Amino Acids; Bacillaceae; Catalysis; Diethyl Pyrocarbonate; Glucosyltransferases; Histidine; In Vitro Techniques; Isoenzymes; Kinetics; Molecular Sequence Data; Peptide Fragments; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
Histidine-834 of human erythrocyte band 3 has an essential role in the conformational changes that occur during the band 3-mediated anion exchange.
Topics: Anion Exchange Protein 1, Erythrocyte; Anions; Chromatography, High Pressure Liquid; Cytosol; Diethyl Pyrocarbonate; Erythrocyte Membrane; Histidine; Humans; Ion Transport; Peptide Fragments; Peptide Mapping; Protein Conformation; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Structure-Activity Relationship; Trypsin | 2003 |
Constitutive activation and uncoupling of the atrial natriuretic peptide receptor by mutations at the dimer interface. Role of the dimer structure in signalling.
Topics: Animals; Arginine; COS Cells; Crystallography, X-Ray; Cyclic GMP; Diethyl Pyrocarbonate; Dimerization; DNA, Complementary; Histidine; Hydrogen Bonding; Kinetics; Mass Spectrometry; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peptides; Protein Conformation; Receptors, Atrial Natriuretic Factor; Signal Transduction; Time Factors; Transfection; Trypsin; Tryptophan | 2004 |
Chemical modification of catalytically essential functional groups of NAD-dependent hydrogenase from Ralstonia eutropha H16.
Topics: Cupriavidus necator; Cysteine; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Hydrogenase; Iodoacetamide; Kinetics; NAD | 2003 |
Purification, tandem mass characterization, and inhibition studies of oxidosqualene-lanosterol cyclase enzyme from bovine liver.
Topics: Amino Acid Sequence; Animals; Benzophenones; Cattle; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Inhibitory Concentration 50; Intramolecular Transferases; Kinetics; Mass Spectrometry; Microsomes, Liver; Molecular Sequence Data; Peptide Fragments; Sequence Analysis, Protein; Sequence Homology, Amino Acid | 2004 |
Binding of the human "electron transferring flavoprotein" (ETF) to the medium chain acyl-CoA dehydrogenase (MCAD) involves an arginine and histidine residue.
Topics: Acyl-CoA Dehydrogenase; Arginine; Binding Sites; Diacetyl; Diethyl Pyrocarbonate; Electron-Transferring Flavoproteins; Histidine; Humans; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid; Spectrophotometry | 2003 |
The structural and functional studies of His119 and His12 in RNase A via chemical modification.
Topics: Animals; Binding Sites; Calorimetry, Differential Scanning; Diethyl Pyrocarbonate; Enzyme Inhibitors; Histidine; Imidazoles; Isoelectric Focusing; Magnetic Resonance Spectroscopy; Protein Conformation; Recombinant Proteins; Ribonuclease, Pancreatic; Structure-Activity Relationship; Temperature | 2003 |
Histidine residues in human phenol sulfotransferases.
Topics: Adenosine Diphosphate; Arylsulfotransferase; Binding Sites; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Histidine; Humans; Protein Conformation; Sequence Alignment; Substrate Specificity; Sulfotransferases; Time | 2004 |
Essential role of histidine 20 in the catalytic mechanism of Escherichia coli peptidyl-tRNA hydrolase.
Topics: Asparagine; Binding Sites; Carboxylic Ester Hydrolases; Catalysis; Diethyl Pyrocarbonate; Escherichia coli Proteins; Fluorescent Dyes; Fluorometry; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Hydroxylamine; Kinetics; Mutagenesis, Site-Directed; Phosphorylcholine; Point Mutation; Substrate Specificity | 2004 |
Mutational analysis of histidine residues in human organic anion transporter 4 (hOAT4).
Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Chlorocebus aethiops; COS Cells; Diethyl Pyrocarbonate; DNA Mutational Analysis; Histidine; Humans; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Organic Anion Transporters, Sodium-Independent | 2004 |
Site-directed mutagenesis of active site residues of phosphite dehydrogenase.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cysteine; Deuterium Exchange Measurement; Diethyl Pyrocarbonate; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; Phosphites; Sequence Alignment | 2005 |
Binding residues and catalytic domain of soluble Saccharomyces cerevisiae processing alpha-glucosidase I.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Amino Acid Sequence; Binding Sites; Bromosuccinimide; Catalysis; Catalytic Domain; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Regulation, Fungal; Glycoside Hydrolases; Glycosylation; Glyoxal; Histidine; Hydrolysis; Lysine; Molecular Sequence Data; Peptides; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Temperature; Tetranitromethane; Time Factors; Trisaccharides; Trypsin; Tryptophan; Tyrosine | 2005 |
Kinetic comparison of procaspase-3 and caspase-3.
Topics: Binding Sites; Caspase 3; Caspases; Catalysis; Crystallography, X-Ray; Cysteine; Diethyl Pyrocarbonate; Enzyme Activation; Enzyme Precursors; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Mutation | 2005 |
Polyhistidine tract expansions in HOXA1 result in intranuclear aggregation and increased cell death.
Topics: Animals; Autistic Disorder; Cell Death; Cell Line, Tumor; Cell Nucleus; Chlorocebus aethiops; Cloning, Molecular; Diethyl Pyrocarbonate; Histidine; Homeodomain Proteins; Humans; Protein Isoforms; Transcription Factors; Ubiquitin | 2005 |
Probing the role of the hyper-reactive histidine residue of arginase.
Topics: Animals; Arginase; Borates; Crystallography, X-Ray; Diethyl Pyrocarbonate; Histidine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Ornithine; Protein Conformation; Rats | 2005 |
Functional contribution of a conserved, mobile loop histidine of phosphoribulokinase.
Topics: Amino Acid Sequence; Binding Sites; Conserved Sequence; Diethyl Pyrocarbonate; Evaluation Studies as Topic; Histidine; Kinetics; Molecular Sequence Data; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Protein Structure, Secondary; Sequence Alignment | 2006 |
The extracellular pH dependency of transport activity by human oligopeptide transporter 1 (hPEPT1) expressed stably in Chinese hamster ovary (CHO) cells: a reason for the bell-shaped activity versus pH.
Topics: Algorithms; Animals; Caco-2 Cells; CHO Cells; Cricetinae; Diethyl Pyrocarbonate; Dipeptides; Extracellular Space; Genetic Vectors; Histidine; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Peptide Transporter 1; Substrate Specificity; Symporters | 2006 |
Catalytic mechanism and structure of viral flavin-dependent thymidylate synthase ThyX.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Catalysis; Chlorella; Conserved Sequence; Crystallography, X-Ray; Diethyl Pyrocarbonate; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Glutamic Acid; Histidine; Kinetics; Molecular Sequence Data; Phycodnaviridae; Sequence Alignment; Structure-Activity Relationship; Substrate Specificity; Thymidylate Synthase | 2006 |
Kinetics of inactivation of phytase (phy A) during modification of histidine residue by IAA and DEP.
Topics: 6-Phytase; Aspergillus; Diethyl Pyrocarbonate; Histidine; Iodoacetic Acid; Kinetics; Protein Denaturation | 2006 |
Characterization of heme-coordinating histidyl residues of cytochrome b5 based on the reactivity with diethylpyrocarbonate: a mechanism for the opening of axial imidazole rings.
Topics: Amino Acid Sequence; Cloning, Molecular; Cytochromes b5; Diethyl Pyrocarbonate; Electron Spin Resonance Spectroscopy; Heme; Histidine; Humans; Hydrogen Bonding; Imidazoles; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2006 |
The role of the histidine-35 residue in the cytocidal action of HM-1 killer toxin.
Topics: Candida albicans; Cell Membrane; Diethyl Pyrocarbonate; Glucosyltransferases; Histidine; Immunoprecipitation; Killer Factors, Yeast; Mutagenesis, Site-Directed; Mutation, Missense; Mycotoxins; Protein Binding; Saccharomyces cerevisiae | 2006 |
Characterization and copper binding properties of human COMMD1 (MURR1).
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Carrier Proteins; Cloning, Molecular; Copper; Diethyl Pyrocarbonate; Dimerization; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Methionine; Molecular Sequence Data; Protein Structure, Quaternary; Sequence Alignment; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2007 |
A base-catalyzed mechanism for dark state recovery in the Avena sativa phototropin-1 LOV2 domain.
Topics: Amino Acid Sequence; Avena; Darkness; Diethyl Pyrocarbonate; Flavin Mononucleotide; Flavoproteins; Histidine; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Models, Molecular; Phototropism; Protein Serine-Threonine Kinases; Protein Structure, Tertiary | 2007 |
Identification of essential histidine and cysteine residues of the H+/organic cation antiporter multidrug and toxin extrusion (MATE).
Topics: 4-Chloromercuribenzenesulfonate; Animals; Antiporters; Biological Transport; Cysteine; Diethyl Pyrocarbonate; Gene Expression; Histidine; Humans; Mutagenesis, Site-Directed; Organic Cation Transport Proteins; Rats; Tetraethylammonium; Toxins, Biological | 2007 |
Purification and some properties of thiosulfate dehydrogenase from Acidithiobacillus ferrooxidans.
Topics: Acidithiobacillus; Ammonium Sulfate; Chromatography, Gel; Chromatography, Ion Exchange; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Isoelectric Point; Molecular Weight; Oxidoreductases; Sodium Dodecyl Sulfate; Substrate Specificity; Time Factors | 2007 |
Copper sensing based on the far-red fluorescent protein, HcRed, from Heteractis crispa.
Topics: Animals; Biosensing Techniques; Cations, Divalent; Circular Dichroism; Copper; Cysteine; Diethyl Pyrocarbonate; Histidine; Iodoacetamide; Luminescent Proteins; Sea Anemones; Sensitivity and Specificity; Spectrometry, Fluorescence | 2007 |
A role for His155 in binding of human prion peptide144-167 to immobilised prion protein.
Topics: Amino Acid Motifs; Circular Dichroism; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Histidine; Humans; Hydrogen-Ion Concentration; Prions; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Surface Plasmon Resonance | 2007 |
Reactivity of histidine and lysine side-chains with diethylpyrocarbonate -- a method to identify surface exposed residues in proteins.
Topics: Animals; Chickens; Diethyl Pyrocarbonate; Histidine; Horses; Humans; Lysine; Molecular Structure; Proteins; Spectrophotometry; Surface Properties | 2008 |
Characterization of heme-coordinating histidyl residues of an engineered six-coordinated myoglobin mutant based on the reactivity with diethylpyrocarbonate, mass spectrometry, and electron paramagnetic resonance spectroscopy.
Topics: Diethyl Pyrocarbonate; Electron Spin Resonance Spectroscopy; Heme; Histidine; Mass Spectrometry; Mutation; Myoglobin; Protein Engineering; Protein Structure, Tertiary | 2008 |
Solution structure of physiological Cu(His)2: novel considerations into imidazole coordination.
Topics: Crystallography, X-Ray; Diethyl Pyrocarbonate; Histidine; Imidazoles; Mass Spectrometry; Molecular Structure; Organometallic Compounds | 2009 |
Chemical modification of the Rieske protein from Thermus thermophilus using diethyl pyrocarbonate modifies ligating histidine 154 and reduces the [2FE-2S] cluster.
Topics: Circular Dichroism; Diethyl Pyrocarbonate; Electron Spin Resonance Spectroscopy; Histidine; Oxidation-Reduction; Proteins; Thermus thermophilus | 2010 |
One octarepeate expansion to the human prion protein alters both the Zn2+ and Cu2+ coordination environments within the octarepeate domain.
Topics: Catalytic Domain; Cations, Divalent; Copper; Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen Peroxide; Oxidation-Reduction; Peptide Fragments; Prions; X-Ray Absorption Spectroscopy; Zinc | 2011 |
Mass spectral studies reveal the structure of Aβ1-16-Cu2+ complex resembling ATCUN motif.
Topics: Amino Acid Motifs; Amyloid beta-Peptides; Binding Sites; Coordination Complexes; Copper; Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Nickel; Peptide Fragments; Protein Binding; Serum Albumin; Tandem Mass Spectrometry | 2012 |
Identification of histidine residues involved in Zn(2+) binding to αA- and αB-crystallin by chemical modification and MALDI TOF mass spectrometry.
Topics: alpha-Crystallin A Chain; alpha-Crystallin B Chain; Amino Acid Sequence; Diethyl Pyrocarbonate; Histidine; Humans; Molecular Sequence Data; Peptide Fragments; Protein Binding; Protein Stability; Sequence Analysis, Protein; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin; Zinc | 2012 |
Evidence for the presence of a critical histidine residue at the active site in glyceraldehyde-3-phosphate dehydrogenase of Ehrlich ascites carcinoma cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Catalytic Domain; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Gene Expression Regulation, Enzymologic; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Kinetics; Mice | 2004 |
Involvement of Histidine Residue His382 in pH Regulation of MCT4 Activity.
Topics: Animals; Diethyl Pyrocarbonate; Female; Histidine; Humans; Hydrogen-Ion Concentration; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Mutagenesis, Site-Directed; Oocytes; Organisms, Genetically Modified; Xenopus laevis; Zinc | 2014 |
Copper(II) partially protects three histidine residues and the N-terminus of amyloid-β peptide from diethyl pyrocarbonate (DEPC) modification.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Cations, Divalent; Copper; Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen-Ion Concentration; Peptide Fragments; Protein Aggregates; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2020 |
Utilization of Hydrophobic Microenvironment Sensitivity in Diethylpyrocarbonate Labeling for Protein Structure Prediction.
Topics: Diethyl Pyrocarbonate; Histidine; Mass Spectrometry; Proteins; Tyrosine | 2021 |
Distinguishing Histidine Tautomers in Proteins Using Covalent Labeling-Mass Spectrometry.
Topics: Chromatography, Liquid; Diethyl Pyrocarbonate; Histidine; Isomerism; Tandem Mass Spectrometry | 2022 |