diethyl-maleate and pentane

diethyl-maleate has been researched along with pentane* in 1 studies

Other Studies

1 other study(ies) available for diethyl-maleate and pentane

Article	Year
Carbon tetrachloride-mediated expiration of pentane and chloroform by the intact rat: the effects of pretreatment with diethyl maleate, SKF-525A and phenobarbital. Toxicology letters, 1982, Volume: 11, Issue:1-2 Measurements were made of pentane, a produce of lipid peroxidation, and chloroform (CHCl3), a product of the reproductive metabolism of carbon tetrachloride (CCl4), expired by rats administered CCl4 plus either phenobarbital (PB), 2-diethylaminoethyl-2,2-diphenyl valerate hydrochloride (SKF-525A), or diethyl maleate (DEM). In rats fed a standard laboratory diet, treatment with PB prior to injection of CCl4 increased expiration of both CHCl3 and pentane. SKF-525A pretreatment decreased the metabolism of CCl4 and CCl4-induced lipid peroxidation. DEM, a depleter of intracellular glutathione, increased lipid peroxidation. In rats fed 10% corn oil diets that contained either 0 or 40 IU of dl-alpha-tocopherol acetate, oxidant stresses caused by glutathione depletion and CCl4-intoxication were found to be additive. Topics: Animals; Carbon Tetrachloride; Chloroform; Drug Interactions; Glutathione; Lipid Peroxides; Male; Maleates; Pentanes; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains	1982

Article

Year

Carbon tetrachloride-mediated expiration of pentane and chloroform by the intact rat: the effects of pretreatment with diethyl maleate, SKF-525A and phenobarbital.

Toxicology letters, 1982, Volume: 11, Issue:1-2

Measurements were made of pentane, a produce of lipid peroxidation, and chloroform (CHCl3), a product of the reproductive metabolism of carbon tetrachloride (CCl4), expired by rats administered CCl4 plus either phenobarbital (PB), 2-diethylaminoethyl-2,2-diphenyl valerate hydrochloride (SKF-525A), or diethyl maleate (DEM). In rats fed a standard laboratory diet, treatment with PB prior to injection of CCl4 increased expiration of both CHCl3 and pentane. SKF-525A pretreatment decreased the metabolism of CCl4 and CCl4-induced lipid peroxidation. DEM, a depleter of intracellular glutathione, increased lipid peroxidation. In rats fed 10% corn oil diets that contained either 0 or 40 IU of dl-alpha-tocopherol acetate, oxidant stresses caused by glutathione depletion and CCl4-intoxication were found to be additive.

Topics: Animals; Carbon Tetrachloride; Chloroform; Drug Interactions; Glutathione; Lipid Peroxides; Male; Maleates; Pentanes; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains

1982