Page last updated: 2024-08-21

diepoxybutane and guanine

diepoxybutane has been researched along with guanine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (55.56)18.2507
2000's3 (33.33)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, YP; Sangaiah, R; Swenberg, JA; Upton, PB1
Blair, IA; Chaudhary, AK; Kambouris, SJ1
Sangaiah, R; Swenberg, JA; Yen, TY1
Blair, IA; Chaudhary, AK; Kambouris, SJ; Meng, Q; Oe, T; Recio, L; Walker, VE; Wherli, S1
Adler, ID; Kilpeläinen, I; Koivisto, P; Pacchierotti, F; Peltonen, K; Rasanen, I1
Carmical, JR; Harris, CM; Harris, TM; Kowalczyk, A; Lloyd, RS; Nechev, LV; Van Houten, B; Zou, Y1
Anderson, C; Hodge, J; Park, S; Tretyakova, N1
Anderson, C; Goggin, M; Park, S; Swenberg, J; Tretyakova, N; Walker, V1
Cho, SH; Guengerich, FP1

Other Studies

9 other study(ies) available for diepoxybutane and guanine

ArticleYear
Macromolecular adducts of butadiene.
    Toxicology, 1996, Oct-28, Volume: 113, Issue:1-3

    Topics: Adenine; Animals; Butadienes; DNA; Epoxy Compounds; Female; Globins; Guanine; Guanosine; Humans; Male; Mice; Rats; Species Specificity

1996
Liquid chromatography/electrospray ionization tandem mass spectroscopy (LC/ESI MS/MS) analysis of 1,2-epoxybutene adducts of purine deoxynucleosides.
    Toxicology, 1996, Oct-28, Volume: 113, Issue:1-3

    Topics: Adenine; Carcinogens; Chromatography, Liquid; DNA Adducts; Epoxy Compounds; Guanine; Mass Spectrometry

1996
Synthesis, characterization, and in vitro quantitation of N-7-guanine adducts of diepoxybutane.
    Chemical research in toxicology, 1997, Volume: 10, Issue:7

    Topics: Carcinogens; Chromatography, High Pressure Liquid; DNA; Epoxy Compounds; Guanine; Guanosine; Ilizarov Technique; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry, Ultraviolet

1997
Persistence of N7-(2,3,4-trihydroxybutyl)guanine adducts in the livers of mice and rats exposed to 1,3-butadiene.
    Chemical research in toxicology, 1999, Volume: 12, Issue:3

    Topics: Animals; Butadienes; Chromatography, Liquid; DNA Adducts; Epoxy Compounds; Female; Guanine; Half-Life; Hydrolysis; Inhalation Exposure; Liver; Mass Spectrometry; Mice; Mice, Inbred Strains; Mutagens; Rats; Rats, Inbred F344; Spectrophotometry, Ultraviolet; Stereoisomerism

1999
Butadiene diolepoxide- and diepoxybutane-derived DNA adducts at N7-guanine: a high occurrence of diolepoxide-derived adducts in mouse lung after 1,3-butadiene exposure.
    Carcinogenesis, 1999, Volume: 20, Issue:7

    Topics: Animals; Butadienes; Cell Line; Chromatography, High Pressure Liquid; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Glycols; Guanine; Humans; Inhalation Exposure; Lung; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Conformation; Molecular Structure; Phosphorus Radioisotopes

1999
Butadiene-induced intrastrand DNA cross-links: a possible role in deletion mutagenesis.
    The Journal of biological chemistry, 2000, Jun-30, Volume: 275, Issue:26

    Topics: Adenosine Triphosphatases; Bacterial Proteins; Base Sequence; Butadienes; Chromatography, High Pressure Liquid; Cross-Linking Reagents; DNA; DNA Adducts; DNA-Binding Proteins; DNA, Complementary; Epoxy Compounds; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Genes, ras; Guanine; Humans; Molecular Sequence Data; Mutagenesis; Mutagens; Nucleic Acid Hybridization; Oligonucleotides; Stereoisomerism

2000
Guanine-adenine DNA cross-linking by 1,2,3,4-diepoxybutane: potential basis for biological activity.
    Chemical research in toxicology, 2004, Volume: 17, Issue:12

    Topics: Adenine; DNA Adducts; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Guanine; Magnetic Resonance Spectroscopy; Mutagens; Stereoisomerism

2004
Quantitative high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry analysis of the adenine-guanine cross-links of 1,2,3,4-diepoxybutane in tissues of butadiene-exposed B6C3F1 mice.
    Chemical research in toxicology, 2008, Volume: 21, Issue:5

    Topics: Adenine; Animals; Butadienes; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; DNA; Epoxy Compounds; Guanine; Hydrolysis; Kinetics; Mice; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry

2008
In vivo roles of conjugation with glutathione and O6-alkylguanine DNA-alkyltransferase in the mutagenicity of the bis-electrophiles 1,2-dibromoethane and 1,2,3,4-diepoxybutane in mice.
    Chemical research in toxicology, 2013, Nov-18, Volume: 26, Issue:11

    Topics: Animals; Butadienes; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; DNA Adducts; DNA Mutational Analysis; Epoxy Compounds; Ethylene Dibromide; Glutathione; Glutathione Transferase; Guanine; Liver; Male; Mice; Mice, Transgenic; Mutagenicity Tests; Mutation; Mutation Rate; O(6)-Methylguanine-DNA Methyltransferase; Spectrometry, Mass, Electrospray Ionization

2013