dideoxyadenosine has been researched along with zidovudine in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (34.21) | 18.7374 |
| 1990's | 17 (44.74) | 18.2507 |
| 2000's | 4 (10.53) | 29.6817 |
| 2010's | 2 (5.26) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Baba, M; Hayakawa, H; Miyasaka, T; Nitta, I; Sakamaki, T; Sekiya, K; Shigeta, S; Takashima, H; Tanaka, H; Ubasawa, M | 1 |
| Corbett, TH; Court, BA; Kessel, D; Phadtare, S; Renis, HE; Zimlicka, J | 1 |
| Baba, M; De Clercq, E; Miyasaka, T; Nitta, I; Sekiya, K; Shigeta, S; Takashima, H; Tanaka, H; Ubasawa, M; Walker, RT | 1 |
| Aoki, S; Barchi, JJ; Driscoll, JS; Ford, H; Kelley, JA; Marquez, VE; Mitsuya, H; Shirasaka, T | 1 |
| Clement, J; Erickson, J; Hayashi, S; Herrin, T; Kern, E; Norbeck, DW; Plattner, JJ; Rosenbrook, W; Sham, H; Swanson, R | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Hayakawa, H; Miyasaka, T; Tanaka, H; Walker, RT | 1 |
| Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R; Van Aerschot, A | 1 |
| Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R | 1 |
| Antonenko, SV; Chentsova, NP; Kukhar, VP; Luik, AI; Poda, GI; Tetko, IV | 1 |
| Balzarini, J; De Clercq, E; Knispel, T; Meier, C | 1 |
| Balzarini, J; De Clercq, E; Knispel, T; Marquez, VE; Meier, C; Siddiqui, MA | 1 |
| Boryski, J; Collu, G; Kraszewski, A; La Colla, P; Loddo, R; Romanowska, J; Sanna, G; Secci, B; Stawiński, J; Szymańska-Michalak, A | 1 |
| Balzarini, J; Bourdin, C; Chamberlain, S; Derudas, M; Hamon, N; Hinsinger, K; Introini, A; Kandil, S; Kolykhalov, A; Madela, K; Margolis, L; McGuigan, C; Meneghesso, S; Pertusati, F; Serpi, M; Slusarczyk, M; Vanpouille, C; Vernachio, J | 1 |
| Aubertin, AM; Périgaud, C; Peyrottes, S; Villard, AL | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Cao, W; Fuchs, BA; Germolec, DR; Luster, MI; Munson, AE; Prejean, JD; Rosenthal, GJ; Shopp, G; Thompson, MB; Tomaszewski, JE | 1 |
| Lange, W; Masihi, KN; Rohde-Schulz, B | 1 |
| Hua, M; Vince, R | 1 |
| Benveniste, RE; Follis, KE; Tsai, CC | 1 |
| Chisaka, O; Matsubara, K; Nagahata, T; Tsurimoto, T; Ueda, K | 1 |
| Ganser, A; Greher, J; Hoelzer, D; Staszewski, S; Völkers, B | 1 |
| de Noronha, F; Postie, L; Roneker, C; Tavares, L | 1 |
| Blair, PC; Fort, MM; Fuchs, BA; Germolec, DR; Luster, MI; McCay, JA; Munson, AE; Thompson, M; Tomaszewski, JE; White, KL | 1 |
| Carson, DA; Kornbluth, RS; Richman, DD | 1 |
| Broder, S; Mitsuya, H | 1 |
| Pardridge, WM; Terasaki, T | 1 |
| Cooney, DA; Gartner, S; Gerrard, TL; Hao, Z; Hartman, NR; Johns, DG; Perno, CF; Popovic, M; Wilson, YA; Yarchoan, R | 1 |
| Balzarini, J | 1 |
| Aubertin, AM; Benzaria, S; Girardet, JL; Gosselin, G; Imbach, JL; Kirn, A; Maury, G; Pelicano, H; Perigaud, C | 1 |
| Sommadossi, JP | 1 |
| Baker, CJ; Bremer, JW; Dimitrov, DH; Doyle, M; Hollinger, FB; Kline, MW; Shearer, WT | 1 |
| Biondi, R; Bourdais, J; Guerreiro, C; Janin, J; Lascu, I; Sarfati, S; Véron, M | 1 |
| Driscoll, JS; Fridland, A; Hui, FK; Kavlick, MF; Mitsuya, H; Srinivas, RV; Tanaka, M; Ueno, T | 1 |
| Knecht, W; Munch-Petersen, B; Piskur, J | 1 |
| Chang, SL; Griesgraber, G; Wagner, CR | 1 |
| Harada, Y; Liu, X; Mizushina, Y; Ogawara, T; Ogimura, Y; Saneyoshi, M; Takahashi, H; Yamaguchi, T | 1 |
| Asif, G; Coats, SJ; Detorio, M; Koontz, D; Mellors, JW; Meteer, JD; Schinazi, RF; Sluis-Cremer, N; Solomon, S; Zhang, HW | 1 |
2 review(s) available for dideoxyadenosine and zidovudine
| Article | Year |
|---|---|
Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives.
Topics: Animals; Antiviral Agents; Dideoxyadenosine; Dideoxynucleosides; Humans; Lamivudine; Purines; Pyrimidines; Retroviridae; Spiro Compounds; Stavudine; Thymidine; Uridine; Zalcitabine; Zidovudine | 1994 |
[What is known about the cellular and molecular pharmacodynamics of nucleosides?].
Topics: Didanosine; Dideoxyadenosine; Dideoxynucleosides; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Hematopoietic Stem Cells; HIV-1; Humans; In Vitro Techniques; Zidovudine | 1993 |
36 other study(ies) available for dideoxyadenosine and zidovudine
| Article | Year |
|---|---|
A new class of HIV-1-specific 6-substituted acyclouridine derivatives: synthesis and anti-HIV-1 activity of 5- or 6-substituted analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).
Topics: Antiviral Agents; Cell Line; Cell Survival; HIV-1; Humans; Indicators and Reagents; Molecular Structure; Structure-Activity Relationship; Thymine | 1991 |
Unsaturated and carbocyclic nucleoside analogues: synthesis, antitumor, and antiviral activity.
Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Friend murine leukemia virus; HIV-1; HIV-2; Humans; Indicators and Reagents; Leukemia L1210; Mice; Molecular Structure; Nucleosides; Rauscher Virus; Structure-Activity Relationship | 1991 |
Synthesis and anti-HIV activity of 2-, 3-, and 4-substituted analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).
Topics: Antiviral Agents; Cell Line; Cells, Cultured; HIV-1; HIV-2; Humans; Indicators and Reagents; Lymphocyte Activation; Lymphocytes; Magnetic Resonance Spectroscopy; Molecular Structure; Structure-Activity Relationship; Thymine | 1991 |
Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs.
Topics: Adenosine Deaminase; Antiviral Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Kinetics; Prodrugs; Structure-Activity Relationship | 1991 |
Cyclobut-A and cyclobut-G: broad-spectrum antiviral agents with potential utility for the therapy of AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Animals; Antiviral Agents; Guanine; Herpesviridae; HIV; Humans; Mice; Microbial Sensitivity Tests | 1990 |
A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.
Topics: Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; HIV-1; HIV-2; Mice; Molecular Conformation; Reverse Transcriptase Inhibitors; Thymine; Virus Replication | 1989 |
3'-Fluoro-2',3'-dideoxy-5-chlorouridine: most selective anti-HIV-1 agent among a series of new 2'- and 3'-fluorinated 2',3'-dideoxynucleoside analogues.
Topics: Antiviral Agents; Chemical Phenomena; Chemistry; Dideoxynucleosides; HIV-1 | 1989 |
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication | 1987 |
Synthesis and anti-HIV activity of various 2'- and 3'-substituted 2',3'-dideoxyadenosines: a structure-activity analysis.
Topics: Antiviral Agents; Deoxyadenosines; Dideoxyadenosine; HIV; Structure-Activity Relationship | 1987 |
HIV-1 reverse transcriptase inhibitor design using artificial neural networks.
Topics: Algorithms; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Neural Networks, Computer; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; T-Lymphocytes; Zidovudine | 1994 |
cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system.
Topics: 3T3 Cells; Adenosine Deaminase; Adenosine Monophosphate; AMP Deaminase; Animals; Anti-HIV Agents; Cell Line; Cell Transformation, Viral; Deoxyadenine Nucleotides; Dideoxynucleotides; Drug Delivery Systems; Drug Evaluation, Preclinical; HIV-1; HIV-2; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mice; Organophosphates; Prodrugs; Structure-Activity Relationship; Virus Replication | 1999 |
cycloSal-Pronucleotides of 2'-fluoro-ara- and 2'-fluoro-ribo-2',3'- dideoxyadenosine as a strategy to bypass a metabolic blockade.
Topics: 3T3 Cells; Adenosine Deaminase; AMP Deaminase; Animals; Anti-HIV Agents; Cell Line; Dideoxyadenosine; Drug Delivery Systems; HIV-1; HIV-2; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mice; Organophosphates; Prodrugs; Structure-Activity Relationship; Virus Replication | 1999 |
Aryl nucleoside H-phosphonates. Part 16: synthesis and anti-HIV-1 activity of di-aryl nucleoside phosphotriesters.
Topics: Anti-HIV Agents; Cell Line; Cells, Cultured; HIV; Humans; Hydroxy Acids; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Nucleotides; Organophosphonates; Virus Replication | 2009 |
Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.
Topics: Anti-HIV Agents; Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Prodrugs; Structure-Activity Relationship | 2013 |
An original pronucleotide strategy for the simultaneous delivery of two bioactive drugs.
Topics: Anti-HIV Agents; Antiviral Agents; Cell Line, Tumor; Cell Survival; Drug Carriers; HIV-1; Humans; Nucleotides; Prodrugs | 2021 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Experimental studies of the hematologic and immune system toxicity of nucleoside derivatives used against HIV infection.
Topics: Animals; Bone Marrow; Didanosine; Dideoxyadenosine; Female; HIV Infections; Immune System; Immunoglobulin M; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Zalcitabine; Zidovudine | 1991 |
Exacerbation of human immunodeficiency virus infection in promonocytic cells by bacterial immunomodulators.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Cell Line; Cord Factors; Dideoxyadenosine; Glycolipids; HIV-1; Humans; Interferon-gamma; Interleukin-1; Lipid A; Monocytes; Tumor Necrosis Factor-alpha; Virus Replication; Zidovudine | 1990 |
Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides.
Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Dideoxyadenosine; Dideoxynucleosides; HIV; Leukemia P388; Molecular Structure; Purine Nucleosides; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Replication; Zidovudine | 1990 |
Antiviral effects of 3'-azido-3'-deoxythymidine, 2',3'-dideoxycytidine, and 2',3'-dideoxyadenosine against simian acquired immunodeficiency syndrome-associated type D retrovirus in vitro.
Topics: Animals; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Dideoxyadenosine; Dideoxynucleosides; Humans; Macaca mulatta; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Zalcitabine; Zidovudine | 1988 |
An in vitro system for screening anti-hepatitis B virus drugs.
Topics: Acyclovir; Adenine; Antiviral Agents; Blotting, Southern; Carcinoma, Hepatocellular; Cytarabine; Dideoxyadenosine; Dideoxynucleosides; DNA Replication; DNA, Viral; Hepatitis B virus; Humans; Interferons; Liver Neoplasms; Tumor Cells, Cultured; Vidarabine; Virus Replication; Zalcitabine; Zidovudine | 1989 |
Inhibitory effect of azidothymidine, 2'-3'-dideoxyadenosine, and 2'-3'-dideoxycytidine on in vitro growth of hematopoietic progenitor cells from normal persons and from patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Bone Marrow; Colony-Forming Units Assay; Deoxyribonucleosides; Dideoxyadenosine; Dideoxynucleosides; Dose-Response Relationship, Drug; Growth Inhibitors; Hematopoiesis; Hematopoietic Stem Cells; Humans; Zalcitabine; Zidovudine | 1989 |
Testing of nucleoside analogues in cats infected with feline leukemia virus: a model.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antibodies, Viral; Antiviral Agents; Cats; Cell Line; Didanosine; Dideoxyadenosine; Dideoxynucleosides; Disease Models, Animal; Drug Evaluation, Preclinical; Immunologic Deficiency Syndromes; Leukemia Virus, Feline; Leukemia, Experimental; Nucleosides; Specific Pathogen-Free Organisms; Virus Replication; Zalcitabine; Zidovudine | 1989 |
A comparison of three nucleoside analogs with anti-retroviral activity on immune and hematopoietic functions in mice: in vitro toxicity to precursor cells and microstromal environment.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antigen-Antibody Reactions; Antiviral Agents; Bone Marrow; Dideoxyadenosine; Female; Hematopoiesis; HIV; Immunity, Cellular; Macrophages; Mice; Mice, Inbred C57BL; Spleen; Stem Cells; T-Lymphocytes; Virus Replication; Zalcitabine; Zidovudine | 1989 |
Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages.
Topics: Adenosine Kinase; Cell Line; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Dideoxyadenosine; HIV; Humans; Macrophages; Phosphorylation; T-Lymphocytes; Thymidine; Thymidine Kinase; Uridine Kinase; Virus Replication; Zalcitabine; Zidovudine | 1987 |
Inhibition of infectivity and replication of HIV-2 and SIV in helper T-cells by 2',3'-dideoxynucleosides in vitro.
Topics: Cytopathogenic Effect, Viral; Deoxyadenosines; Deoxycytidine; Dideoxyadenosine; HIV; In Vitro Techniques; Nucleosides; Retroviridae; T-Lymphocytes, Helper-Inducer; Thymidine; Viral Proteins; Virus Replication; Zalcitabine; Zidovudine | 1988 |
Restricted transport of 3'-azido-3'-deoxythymidine and dideoxynucleosides through the blood-brain barrier.
Topics: Animals; Antiviral Agents; Blood-Brain Barrier; Deoxyadenosines; Deoxycytidine; Dideoxyadenosine; Liver; Male; Rats; Rats, Inbred Strains; Thymidine; Zalcitabine; Zidovudine | 1988 |
Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides.
Topics: Antiviral Agents; Deoxycytidine Kinase; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; In Vitro Techniques; Macrophages; Monocytes; Phosphorylation; Thymidine Kinase; Time Factors; Virus Replication; Zalcitabine; Zidovudine | 1988 |
Equal inhibition of the replication of human immunodeficiency virus in human T-cell culture by ddA bis(SATE)phosphotriester and 3'-azido-2',3'-dideoxythymidine.
Topics: Antiviral Agents; Cell Line; Dideoxyadenosine; Drug Evaluation, Preclinical; HIV; Humans; T-Lymphocytes; Virus Replication; Zidovudine | 1994 |
Study of human immunodeficiency virus resistance to 2'-3'-dideoxyinosine and zidovudine in sequential isolates from pediatric patients on long-term therapy.
Topics: Child; Child, Preschool; Dideoxyadenosine; Drug Resistance, Microbial; Female; HIV; HIV Seropositivity; Humans; Infant; Male; Zidovudine | 1993 |
Cellular phosphorylation of anti-HIV nucleosides. Role of nucleoside diphosphate kinase.
Topics: Animals; Antiviral Agents; Binding Sites; Dictyostelium; Dideoxyadenosine; Dideoxynucleosides; Humans; Kinetics; Nucleoside-Diphosphate Kinase; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Zidovudine | 1996 |
In vitro induction of human immunodeficiency virus type 1 variants resistant to 2'-beta-Fluoro-2',3'-dideoxyadenosine.
Topics: Animals; Anti-HIV Agents; COS Cells; Deoxyadenine Nucleotides; Dideoxyadenosine; Dideoxynucleotides; Drug Resistance, Microbial; Genes, pol; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine | 1997 |
Identification of residues involved in the specificity and regulation of the highly efficient multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster.
Topics: Animals; Cytarabine; Dideoxyadenosine; Directed Molecular Evolution; Drosophila melanogaster; Enzyme Activation; Feedback; Inhibitory Concentration 50; Kinetics; Mutation; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Polymerase Chain Reaction; Substrate Specificity; Thymidine; Thymine Nucleotides; Zalcitabine; Zidovudine | 2000 |
Comparison of the antiviral activity of hydrophobic amino acid phosphoramidate monoesters of 2'3'-dideoxyadenosine (DDA) and 3'-azido-3'-deoxythymidine (AZT).
Topics: Amides; Amino Acids; Antiviral Agents; Cells, Cultured; Chromatography, Thin Layer; Dideoxyadenosine; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Phosphoric Acids; Spectrometry, Mass, Fast Atom Bombardment; Zidovudine | 2001 |
3'-Azido-2',3'-dideoxynucleoside 5'-triphosphates inhibit telomerase activity in vitro, and the corresponding nucleosides cause telomere shortening in human HL60 cells.
Topics: Antineoplastic Agents; Cell Proliferation; Dideoxyadenosine; Dideoxynucleosides; Dideoxynucleotides; DNA; Enzyme Inhibitors; HeLa Cells; HL-60 Cells; Humans; Telomerase; Telomere; Zidovudine | 2007 |
The base component of 3'-azido-2',3'-dideoxynucleosides influences resistance mutations selected in HIV-1 reverse transcriptase.
Topics: Anti-HIV Agents; Azides; Base Sequence; Dideoxyadenosine; Dideoxynucleosides; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Mutagenesis, Site-Directed; Reverse Transcriptase Inhibitors; Sequence Analysis, RNA; Zalcitabine; Zidovudine | 2011 |