dideoxyadenosine has been researched along with didanosine in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (14.71) | 18.7374 |
| 1990's | 24 (70.59) | 18.2507 |
| 2000's | 4 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, BD; Broder, S; Huryn, DM; Mitsuya, H; Sim, I; Sluboski, BC; Tam, SY; Weigele, M | 1 |
| Aoki, S; Barchi, JJ; Driscoll, JS; Ford, H; Kelley, JA; Marquez, VE; Mitsuya, H; Shirasaka, T | 1 |
| Aoki, S; Broder, S; Driscoll, JS; Ford, H; Johns, DG; Kelley, JA; Marquez, VE; Mitsuya, H; Roth, JS; Tseng, CK | 1 |
| Ahn, SK; Beach, JW; Chu, CK; Doboszewski, B; Jeong, LS; Lin, ZX; Schinazi, RF; Ullas, GV | 1 |
| Antonenko, SV; Chentsova, NP; Kukhar, VP; Luik, AI; Poda, GI; Tetko, IV | 1 |
| Averett, DR; Burns, CL; English, ML; Frick, LW; Holmes, TJ; Koszalka, GW; Krenitsky, TA; Spector, T; St Clair, MH | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Chattopadhyaya, J; Koole, LH; Plavec, J | 1 |
| Nagaoka, H; Nohta, H; Ohkura, Y; Saito, M | 1 |
| Nair, V; Sells, TB | 1 |
| Cao, W; Fuchs, BA; Germolec, DR; Luster, MI; Munson, AE; Prejean, JD; Rosenthal, GJ; Shopp, G; Thompson, MB; Tomaszewski, JE | 1 |
| Ahluwalia, GS; Broder, S; Cooney, DA; Fridland, A; Hartman, NR; Johns, DG; Kageyama, S; Mitsuya, H | 1 |
| Gao, YG; Liaw, YC; Marquez, VE; Wang, AH | 1 |
| Chang, MJ; Kluwe, WM; Page, JG; Placke, ME; Tomaszewski, JE; Wientjes, MG | 1 |
| Broder, S; Hartman, NR; Johns, DG; Marczyk, KS; Pluda, JM; Thomas, RV; Yarchoan, R | 1 |
| Balzarini, J; De Clercq, E; Naesens, L; Robins, MJ | 1 |
| Irie, Y; Kobayashi, K; Shirae, H; Shiragami, H; Yasuda, N; Yokozeki, K | 1 |
| Klunk, LJ; Russell, JW | 1 |
| el Dareer, SM; Hill, DL; Kalin, JR; Tillery, KF | 1 |
| de Noronha, F; Postie, L; Roneker, C; Tavares, L | 1 |
| Hill, DL; Kalin, JR | 1 |
| Balis, FM; Godwin, KS; Hawkins, ME; McCully, CM; Mitsuya, H; Murakami, K; Poplack, DG | 1 |
| Ahluwalia, GS; Cooney, DA; Driscoll, JS; Johns, DG; Mitsuya, H; Shirasaka, T | 1 |
| Sommadossi, JP | 1 |
| Ahluwalia, GS; Cooney, DA; Driscoll, JS; Johns, DG; Mitsuya, H | 1 |
| Comereski, CR; Davidson, TJ; Hopper, LD; Kelly, WA; Oleson, FB; Warner, WA | 1 |
| Campbell, DA; Shah, VR; Shyu, WC; Srinivas, NR | 1 |
| Anderson, BD; Morgan, ME; Singhal, D | 2 |
| Boudinot, FD; Chu, CK; Cretton-Scott, E; Kotra, LP; Koudriakova, T; Manouilov, KK; Schinazi, RF; Shanmuganathan, K; Sommadossi, JP | 1 |
| Dai, F; Ford, H; Kavlick, MF; Kelley, JA; Lietzau, J; Malinowski, N; Welles, L; Yarchoan, R; Zhang, H | 1 |
| Dickman, K; Lake-Bakaar, G; Lyubsky, S; Mazzoccoli, V | 1 |
| Becher, F; Benech, H; Boutet, V; Couerbe, P; Ezan, E; Gale, J; Goujard, C; Grassi, J; Pruvost, A | 1 |
| Anderson, BD; DeGraw, RT | 1 |
1 review(s) available for dideoxyadenosine and didanosine
| Article | Year |
|---|---|
[What is known about the cellular and molecular pharmacodynamics of nucleosides?].
Topics: Didanosine; Dideoxyadenosine; Dideoxynucleosides; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Hematopoietic Stem Cells; HIV-1; Humans; In Vitro Techniques; Zidovudine | 1993 |
1 trial(s) available for dideoxyadenosine and didanosine
| Article | Year |
|---|---|
Pharmacokinetics of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine in patients with severe human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; AIDS-Related Complex; Biological Availability; Clinical Trials as Topic; Didanosine; Dideoxyadenosine; Female; Humans; Male | 1990 |
32 other study(ies) available for dideoxyadenosine and didanosine
| Article | Year |
|---|---|
Synthesis and anti-HIV activity of isonucleosides.
Topics: Antiviral Agents; Cells, Cultured; Chromatography, Liquid; Dideoxynucleosides; Drug Stability; Gene Products, gag; HIV-1; Humans; Isomerism; Monocytes; Spectrum Analysis; Virus Replication | 1992 |
Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs.
Topics: Adenosine Deaminase; Antiviral Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Kinetics; Prodrugs; Structure-Activity Relationship | 1991 |
Acid-stable 2'-fluoro purine dideoxynucleosides as active agents against HIV.
Topics: Antiviral Agents; Drug Stability; Gene Products, gag; HIV; HIV Core Protein p24; Lymphocyte Activation; Purine Nucleosides; Viral Core Proteins | 1990 |
Synthesis and structure-activity relationships of 6-substituted 2',3'-dideoxypurine nucleosides as potential anti-human immunodeficiency virus agents.
Topics: Antiviral Agents; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; Microbial Sensitivity Tests; Structure-Activity Relationship | 1990 |
HIV-1 reverse transcriptase inhibitor design using artificial neural networks.
Topics: Algorithms; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Neural Networks, Computer; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; T-Lymphocytes; Zidovudine | 1994 |
Novel 6-alkoxypurine 2',3'-dideoxynucleosides as inhibitors of the cytopathic effect of the human immunodeficiency virus.
Topics: Adenosine Deaminase; Animals; Chemical Phenomena; Chemistry, Physical; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV-1; Humans; In Vitro Techniques; Male; Mice; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thymidine Phosphorylase | 1993 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Structural analysis of 2',3'-dideoxyinosine, 2',3'-dideoxyadenosine, 2',3'-dideoxyguanosine and 2',3'-dideoxycytidine by 500-MHz 1H-NMR spectroscopy and ab-initio molecular orbital calculations.
Topics: Didanosine; Dideoxyadenosine; Dideoxynucleosides; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Spectrum Analysis; Structure-Activity Relationship; Temperature; Thermodynamics; Zalcitabine | 1992 |
Determination of 2',3'-dideoxyinosine and 2',3'-dideoxyadenosine in rat plasma by high-performance liquid chromatography with precolumn fluorescence derivatization.
Topics: Animals; Chromatography, High Pressure Liquid; Didanosine; Dideoxyadenosine; Male; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1992 |
Interpretation of the roles of adenylosuccinate lyase and of AMP deaminase in the anti-HIV activity of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
Topics: Adenosine; Adenylosuccinate Lyase; AMP Deaminase; Deoxyadenine Nucleotides; Didanosine; Dideoxyadenosine; Dideoxynucleotides; HIV; Succinates | 1992 |
Experimental studies of the hematologic and immune system toxicity of nucleoside derivatives used against HIV infection.
Topics: Animals; Bone Marrow; Didanosine; Dideoxyadenosine; Female; HIV Infections; Immune System; Immunoglobulin M; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Zalcitabine; Zidovudine | 1991 |
Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the anti-human immunodeficiency virus nucleosides 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
Topics: Antiviral Agents; Cells, Cultured; Chromatography; Didanosine; Dideoxyadenosine; Drug Synergism; HIV; Humans; IMP Dehydrogenase; Inosine; Inosine Monophosphate; Nucleotides; Phosphorylation; Ribavirin; Stimulation, Chemical | 1991 |
Molecular structures of two new anti-HIV nucleoside analogs: 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)adenine and 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)hypoxanthine.
Topics: Antiviral Agents; Didanosine; Dideoxyadenosine; Dideoxynucleosides; HIV; Molecular Structure; Structure-Activity Relationship; X-Ray Diffraction | 1992 |
Pharmacokinetics of 2',3'-dideoxyadenosine in dogs.
Topics: Administration, Oral; Animals; Didanosine; Dideoxyadenosine; Dogs; Drug Stability; Female; Infusions, Intravenous; Male; Time Factors | 1991 |
Potentiating effect of ribavirin on the in vitro and in vivo antiretrovirus activities of 2',3'-dideoxyinosine and 2',3'-dideoxy-2,6-diaminopurine riboside.
Topics: Animals; Antiviral Agents; Cell Line; Cell Transformation, Viral; Cytopathogenic Effect, Viral; Didanosine; Dideoxyadenosine; Drug Synergism; Fibroblasts; HIV; Humans; Mice; Mice, Inbred Strains; Moloney murine sarcoma virus; Ribavirin; Sarcoma, Experimental; Virus Replication | 1990 |
Production of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine from 2',3'-dideoxyuridine and the corresponding purine bases by resting cells of Escherichia coli AJ 2595.
Topics: Antiviral Agents; Bacteria; Didanosine; Dideoxyadenosine; Dideoxynucleosides; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Temperature | 1989 |
Comparative pharmacokinetics of new anti-HIV agents: 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
Topics: Animals; Antiviral Agents; Biological Availability; Didanosine; Dideoxyadenosine; Dideoxynucleosides; HIV; Male; Mice; Mice, Inbred ICR | 1989 |
Disposition of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine in mice.
Topics: Animals; Chromatography, High Pressure Liquid; Didanosine; Dideoxyadenosine; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Spectrophotometry, Ultraviolet; Tissue Distribution | 1989 |
Testing of nucleoside analogues in cats infected with feline leukemia virus: a model.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antibodies, Viral; Antiviral Agents; Cats; Cell Line; Didanosine; Dideoxyadenosine; Dideoxynucleosides; Disease Models, Animal; Drug Evaluation, Preclinical; Immunologic Deficiency Syndromes; Leukemia Virus, Feline; Leukemia, Experimental; Nucleosides; Specific Pathogen-Free Organisms; Virus Replication; Zalcitabine; Zidovudine | 1989 |
Determination of 2',3'-dideoxyadenosine, 2',3'-dideoxyinosine and 2',3'-dideoxycytidine in biological samples.
Topics: Animals; Antiviral Agents; Cats; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Didanosine; Dideoxyadenosine; Dideoxynucleosides; Female; Half-Life; Injections, Intravenous; Mice; Mice, Inbred Strains; Rats; Rats, Inbred F344; Spectrophotometry, Ultraviolet; Zalcitabine | 1988 |
Pharmacokinetics of dideoxypurine nucleoside analogs in plasma and cerebrospinal fluid of rhesus monkeys.
Topics: Animals; Antiviral Agents; Central Nervous System; Didanosine; Dideoxyadenosine; Dideoxynucleosides; Macaca mulatta; Male; Metabolic Clearance Rate; Models, Biological | 1995 |
Enhancement by 2'-deoxycoformycin of the 5'-phosphorylation and anti-human immunodeficiency virus activity of 2',3'-dideoxyadenosine and 2'-beta-fluoro-2',3'-dideoxyadenosine.
Topics: Adenosine Deaminase Inhibitors; Cell Line; Didanosine; Dideoxyadenosine; Drug Synergism; HIV; IMP Dehydrogenase; Pentostatin; Phosphorylation; Ribavirin | 1994 |
Enhanced stimulation by ribavirin of the 5'-phosphorylation and anti-human immunodeficiency virus activity of purine 2'-beta-fluoro-2',3'-dideoxynucleosides.
Topics: Didanosine; Dideoxyadenosine; Dideoxynucleosides; Drug Synergism; HIV-1; Phosphorylation; Purine Nucleosides; Ribavirin; Structure-Activity Relationship | 1993 |
Acute cardiotoxicity of nucleoside analogs FddA and FddI in rats.
Topics: Administration, Oral; Animals; Antiviral Agents; Behavior, Animal; Body Weight; Didanosine; Dideoxyadenosine; Dose-Response Relationship, Drug; Heart Diseases; Injections, Intravenous; Male; Myocardium; Necrosis; Rats; Rats, Sprague-Dawley; Xanthines | 1993 |
High-performance liquid chromatographic analysis of 2'-fluoro-2',3'-dideoxyadenosine and 2'-fluoro-2',3'-dideoxyinosine in dog plasma and urine.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxyadenosine; Dogs; Male | 1996 |
Role of altered metabolism in dideoxynucleoside pharmacokinetics. Studies of 2'-beta-fluoro-2',3'-dideoxyinosine and 2'-beta-fluoro-2',3'-dideoxyadenosine in rats.
Topics: Adenosine Deaminase Inhibitors; Animals; Anti-HIV Agents; Didanosine; Dideoxyadenosine; Enzyme Inhibitors; Male; Pentostatin; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors | 1996 |
In vitro and in vivo evaluation of 6-azido-2',3'-dideoxy-2'-fluoro-beta-D-arabinofuranosylpurine and N6-methyl-2',3'-dideoxy-2'-fluoro-beta-D-arabinofuranosyladenine as prodrugs of the anti-HIV nucleosides 2'-F-ara-ddA and 2'-F-ara-ddI.
Topics: Animals; Anti-HIV Agents; Azides; Biotransformation; Didanosine; Dideoxyadenosine; Female; Magnetic Resonance Spectroscopy; Mice; Microsomes, Liver; Prodrugs; Spectrophotometry, Ultraviolet; Vidarabine | 1996 |
Role of brain tissue localized purine metabolizing enzymes in the central nervous system delivery of anti-HIV agents 2'-beta-fluoro-2',3'-dideoxyinosine and 2'-beta-fluoro-2',3'-dideoxyadenosine in rats.
Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Anti-HIV Agents; Brain; Brain Chemistry; Didanosine; Dideoxyadenosine; Enzyme Inhibitors; Infusions, Intravenous; Male; Pentostatin; Purine-Nucleoside Phosphorylase; Rats; Rats, Sprague-Dawley | 1997 |
Fluorometric determination of 2'-beta-fluoro-2',3'-dideoxyadenosine 5'-triphosphate, the active metabolite of a new anti-human immunodeficiency virus drug, in human lymphocytes.
Topics: Anti-HIV Agents; Calibration; Cells, Cultured; Chromatography, High Pressure Liquid; Didanosine; Dideoxyadenosine; Fluorometry; Humans; Lymphocytes; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tumor Cells, Cultured | 2001 |
Differential effects of nucleoside analogs on oxidative phosphorylation in human pancreatic cells.
Topics: Antimetabolites; Cells, Cultured; Didanosine; Dideoxyadenosine; DNA, Mitochondrial; Humans; Oxidative Phosphorylation; Pancreas; Zalcitabine | 2001 |
A strategy for liquid chromatography/tandem mass spectrometric assays of intracellular drugs: application to the validation of the triphosphorylated anabolite of antiretrovirals in peripheral blood mononuclear cells.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxyadenosine; Leukocytes, Mononuclear; Spectrometry, Mass, Electrospray Ionization; Stavudine | 2003 |
Determination of carrier-mediated transport of 2',3'-dideoxypurine nucleosides in the rat ileum using a bidirectional perfusion technique.
Topics: Animals; Biological Transport; Didanosine; Dideoxyadenosine; Drug Carriers; Ileum; Intestinal Absorption; Male; Perfusion; Permeability; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |