diclofenac and ximelagatran

diclofenac has been researched along with ximelagatran in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's7 (87.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Andersson, TB; Bredberg, E; Eriksson, UG; Eriksson-Lepkowska, M; Frison, L; Johansson, S; Larsson, M; Thuresson, A1
Fontana, RJ; Tujios, S1
Hawkins, MT; Lewis, JH1
Kaniwa, N; Saito, Y1

Reviews

4 review(s) available for diclofenac and ximelagatran

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Mechanisms of drug-induced liver injury: from bedside to bench.
    Nature reviews. Gastroenterology & hepatology, 2011, Volume: 8, Issue:4

    Topics: Acetaminophen; Animals; Azetidines; Benzylamines; Chemical and Drug Induced Liver Injury; Diclofenac; Floxacillin; Humans; Inactivation, Metabolic; Mice; Mitochondria, Liver; Models, Animal

2011
Latest advances in predicting DILI in human subjects: focus on biomarkers.
    Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:12

    Topics: Antitubercular Agents; Apolipoproteins E; Arylamine N-Acetyltransferase; Azetidines; Benzylamines; Biomarkers; Chemical and Drug Induced Liver Injury; Diclofenac; Floxacillin; HLA-B Antigens; Humans; Liver; Metabolomics; Pharmacogenetics; Polymorphism, Genetic; Proteomics; Risk Factors

2012
Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury.
    Journal of human genetics, 2013, Volume: 58, Issue:6

    Topics: Alleles; Allopurinol; Amoxicillin-Potassium Clavulanate Combination; Azetidines; Benzylamines; Carbamazepine; Chemical and Drug Induced Liver Injury; Diclofenac; Dideoxynucleosides; Drug Hypersensitivity; Floxacillin; Genetic Markers; HLA Antigens; HLA-A Antigens; HLA-B Antigens; HLA-DQ alpha-Chains; Humans; Lapatinib; Pharmacogenetics; Quinazolines; Skin; Stevens-Johnson Syndrome; Ticlopidine

2013

Trials

1 trial(s) available for diclofenac and ximelagatran

ArticleYear
Ximelagatran, an oral direct thrombin inhibitor, has a low potential for cytochrome P450-mediated drug-drug interactions.
    Clinical pharmacokinetics, 2003, Volume: 42, Issue:8

    Topics: Administration, Oral; Adult; Aged; Amidines; Anticoagulants; Area Under Curve; Azetidines; Benzylamines; Cross-Over Studies; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Diclofenac; Drug Interactions; Glycine; Humans; In Vitro Techniques; Infusions, Intravenous; Microsomes, Liver; Middle Aged; Nifedipine; Nordazepam; Prodrugs; Thrombin

2003

Other Studies

3 other study(ies) available for diclofenac and ximelagatran

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011