diclofenac and triiodothyronine

diclofenac has been researched along with triiodothyronine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's4 (20.00)18.2507
2000's5 (25.00)29.6817
2010's9 (45.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barlow, JW; Lim, CF; Raggatt, LE; Stockigt, JR; Topliss, DJ1
Aoyama, A; Demura, H; Demura, R; Koike, S; Kusakabe, K; Natori, Y; Yamaguti, N1
Crook, PR; Fowler, PD; Hothersall, TE1
Hazelton, RA; Ratcliffe, JG; Ratcliffe, WA; Thomson, JA1
Albrecher, B; Eber, O; Langsteger, W; Sternad, H1
Barlow, JW; Blok, RB; Loidl, NM; Raggatt, LE; Scholz, GH; Stockigt, JR; Topliss, DJ1
Buchinger, W; Nadler, K; Pongratz, R; Rainer, F; Semlitsch, G1
Fujino, S; Hikino, H; Kai, T; Kasono, K; Kawakami, M; Konishi, F; Takemoto, N; Yamaguchi, K1
Brandes, RP; Busse, R; Büssemaker, E; Fisslthaler, B; Fleming, I; Larson, CM; Popp, R1
Iwahara, K; Maekawa, M; Tanabe, C2
Mackenzie, LS; Patel, P; Perez-Diaz, N; Tang, L; Zloh, M1
Bombardo, M; Chen, R; Graf, R; Malagola, E; Rudnicka, A; Sonda, S1

Reviews

1 review(s) available for diclofenac and triiodothyronine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for diclofenac and triiodothyronine

ArticleYear
Diclofenac sodium and thyroid function tests.
    Rheumatology and rehabilitation, 1982, Volume: 21, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Female; Humans; Male; Middle Aged; Osteoarthritis; Phenylacetates; Random Allocation; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

1982

Other Studies

18 other study(ies) available for diclofenac and triiodothyronine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Characterization of cytoplasmic T3 binding sites by adsorption to hydroxyapatite: effects of drug inhibitors of T3 and relationship to glutathione-S-transferases.
    Thyroid : official journal of the American Thyroid Association, 1992,Spring, Volume: 2, Issue:1

    Topics: Amiodarone; Animals; Binding Sites; Binding, Competitive; Cytosol; Diclofenac; Dithiothreitol; Dose-Response Relationship, Drug; Durapatite; Furosemide; Glutathione Transferase; Hydrocortisone; Hydroxyapatites; In Vitro Techniques; Iopanoic Acid; Liver; Macaca fascicularis; Mefenamic Acid; Sulfobromophthalein; Taurocholic Acid; Triiodothyronine

1992
[The effects of diclofenac sodium on thyroid function tests in vivo and in vitro].
    Rinsho byori. The Japanese journal of clinical pathology, 1990, Volume: 38, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Protein Binding; Radioimmunoassay; Thyroid Function Tests; Thyroxine; Triiodothyronine

1990
The effect of fenclofenac on thyroid function tests in vivo and in vitro.
    Clinical endocrinology, 1980, Volume: 13, Issue:6

    Topics: Adult; Aged; Arthritis; Diagnostic Errors; Diclofenac; Female; Humans; Male; Middle Aged; Phenylacetates; Thyroid Function Tests; Thyroxine; Triiodothyronine

1980
[Modification of maximal binding capacity and radio-T3/T4 distribution by carbamazepine and diclofenac].
    Acta medica Austriaca, 1993, Volume: 20, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbamazepine; Diclofenac; Female; Humans; Male; Middle Aged; Prealbumin; Reference Values; Serum Albumin; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine

1993
Preferential inhibition of cytoplasmic T3 binding is associated with reduced nuclear binding in cultured cells.
    Thyroid : official journal of the American Thyroid Association, 1996, Volume: 6, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Nucleus; Cells, Cultured; Cytoplasm; Diclofenac; Hepatoblastoma; Humans; Iodine Radioisotopes; Liver Neoplasms; Protein Binding; Triiodothyronine; Tumor Cells, Cultured

1996
[Effect of aceclofenac on thyroid hormone binding and thyroid function].
    Acta medica Austriaca, 2000, Volume: 27, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Male; Thyroglobulin; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

2000
Cross-reactive mechanism for the false elevation of free triiodothyronine in the patients treated with diclofenac.
    Endocrine journal, 2001, Volume: 48, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cross Reactions; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Middle Aged; Reagent Kits, Diagnostic; Triiodothyronine

2001
Hyperthyroidism enhances endothelium-dependent relaxation in the rat renal artery.
    Cardiovascular research, 2003, Jul-01, Volume: 59, Issue:1

    Topics: Acetylcholine; Animals; Biological Factors; Cyclic AMP; Diclofenac; Endothelium, Vascular; Hyperthyroidism; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Potassium Chloride; Rats; Rats, Inbred WKY; Renal Artery; Triiodothyronine; Vasodilation; Vasodilator Agents

2003
No interference by diclofenac with the new Vitros FT3II assay reagent.
    Clinical chemistry, 2004, Volume: 50, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cross Reactions; Diclofenac; Humans; Immunoassay; Reagent Kits, Diagnostic; Thyroid Function Tests; Triiodothyronine

2004
Dilution test for differentiating falsely high serum free triiodothyronine concentrations.
    Clinical chemistry, 2006, Volume: 52, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Autoantibodies; Buffers; Cross Reactions; Diclofenac; False Positive Reactions; Humans; Hyperparathyroidism; Immunoassay; Serum; Triiodothyronine

2006
Evidence that diclofenac and celecoxib are thyroid hormone receptor beta antagonists.
    Life sciences, 2016, Feb-01, Volume: 146

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Computer Simulation; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Male; Mesenteric Arteries; Models, Molecular; Naproxen; Rats; Rats, Wistar; Thyroid Hormone Receptors beta; Triiodothyronine; Vasodilation

2016
Ibuprofen and diclofenac treatments reduce proliferation of pancreatic acinar cells upon inflammatory injury and mitogenic stimulation.
    British journal of pharmacology, 2018, Volume: 175, Issue:2

    Topics: Acinar Cells; Animals; Cell Differentiation; Cell Proliferation; Ceruletide; Cytokines; Diclofenac; Ibuprofen; Inflammation; Male; Mice; Mitogens; Neutrophil Infiltration; Pancreas; Pancreatitis; Triiodothyronine

2018