diclofenac and thromboxane b2

diclofenac has been researched along with thromboxane b2 in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19907 (20.00)18.7374
1990's10 (28.57)18.2507
2000's17 (48.57)29.6817
2010's1 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N1
Fredholm, BB; Granström, E; Jonsson, CE; Oliw, E; Shimizu, Y1
Bendele, AM; Benslay, DN; Hom, JT; Lee, SJ; Lindstrom, TD; Naismith, RW; Ruterbories, KJ; Spaethe, SM1
Baer, GA; Metsä-Ketelä, T; Miralles, J; Palomäki, E; Rorarius, MG; Vapaatalo, H1
Butler, KD; Shand, RA; Wallis, RB1
Barrett, PA; Butler, KD; Shand, RA; Wallis, RB1
Ali, M; Angelo-Khattar, M; Thulesius, O1
Isomäki, H; Laitinen, O; Nissilä, M; Nuotio, P; Nykänen, E; Seppälä, E; Vapaatalo, H1
Aldo-Benson, MA; Benson, MD; Brandt, KD; Chan, K; Ku, E; Lee, W; Liauw, HL; Vyas, K; Waiter, SL1
Duncker, HP; Heller, A; Koch, T; Neuhof, H; Schaible, R; van Ackern, K1
Boyer, S; Falk-Filipsson, A; Låstbom, L; Moldéus, P; Ryrfeldt, A1
Cirino, G; Elliott, SN; McKnight, W; Wallace, JL1
Cecchi, E; Failli, P; Giotti, A; Laffi, G; Mugelli, A; Tosti-Guerra, C; Zilletti, L1
Janzen, R; Koch, T; Münter, K; Neuhof, H; Schmeck, J1
Andrieu, S; Berdeaux, A; Bévérelli, F; Giudicelli, JF; Lebret, M; Maclouf, J1
Brune, K; Geisslinger, G; Krebs, S; Lötsch, J; Muth-Selbach, U; Tegeder, I1
Giuliano, F; Warner, TD1
Arvola, P; Kähönen, M; Kainulainen, H; Mäkynen, H; Mucha, I; Pörsti, I; Riutta, A; Solakivi, T; Wu, X1
Geisslinger, G; Gühring, H; Neupert, W; Tegeder, I1
Arnout, J; Buntinx, A; Dallob, A; De Lepeleire, I; De Schepper, PJ; Depré, M; Ebel, DL; Gertz, BJ; Schwartz, JI; Tanaka, W; Van Hecken, A; Wong, PH; Wynants, K1
Edwards, SR; Grace, RF; Lin, Y; Mather, LE; Power, I1
Catella-Lawson, F; Cucchiara, AJ; DeMarco, S; FitzGerald, GA; Kapoor, SC; Reilly, MP; Tournier, B; Vyas, SN1
Kent, JD; Leese, PT; Recker, DP; Talwalker, S1
Brockmöller, J; Kirchheiner, J; Meineke, I; Meisel, C; Roots, I; Steinbach, N1
Cmiel, A; Mejza, F; Szczeklik, A; Tuleja, E1
Laurent, A; Milosavljev, S; Rordorf, C; Scott, G; Yeh, CM; Yih, L1
Berry, C; Dawson, J; Du, Z; Esser, R; Fox, A; Fujimoto, RA; Haston, W; Kimble, EF; Koehler, J; Marshall, PJ; Peppard, J; Quadros, E; Quintavalla, J; Toscano, K; Urban, L; van Duzer, J; Zhang, X; Zhou, S1
Munsterhjelm, E; Niemi, TT; Rosenberg, PH; Silvanto, M; Ylikorkala, O1
Branson, J; Guillaume, M; Jermany, J; Rordorf, C; Schmouder, R1
Munsterhjelm, E; Niemi, T; Olkkola, KT; Savolainen, S; Scheinin, H; Silvanto, M; Tiainen, P; Ylikorkala, O1
Dahlén, SE; Kumlin, M; Låstbom, L; Ryrfeldt, A; Selg, E1
Cavanaugh, PF; Chappell, DL; Dallob, AL; Flynn, ME; Hilliard, DA; Larson, PJ; Laterza, OF; Miller, J; Royalty, J; Schwartz, JI; Snyder, KM; Wagner, JA1
de Metz, M; Huntjens-Fleuren, HW; Schuijt, MP; Vollaard, EJ1
Buerkle, MA; Hellwig, N; Klauss, V; Krötz, F; Mannell, H; Pircher, J; Pohl, U; Sohn, HY; Struthmann, L1
Gold, M; Kienzler, JL; Nollevaux, F1

Trials

11 trial(s) available for diclofenac and thromboxane b2

ArticleYear
Effects of peri-operatively administered diclofenac and indomethacin on blood loss, bleeding time and plasma prostanoids in man.
    European journal of anaesthesiology, 1989, Volume: 6, Issue:5

    Topics: Adult; Aged; Bleeding Time; Blood Volume Determination; Diclofenac; Dinoprostone; Double-Blind Method; Female; Genital Diseases, Female; Humans; Indomethacin; Middle Aged; Platelet Function Tests; Randomized Controlled Trials as Topic; Thromboxane B2

1989
Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers.
    Journal of clinical pharmacology, 2000, Volume: 40, Issue:10

    Topics: Adolescent; Adult; Bleeding Time; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Lipopolysaccharides; Meloxicam; Membrane Proteins; Middle Aged; Naproxen; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfones; Thiazines; Thiazoles; Thromboxane B2

2000
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin.
    The New England journal of medicine, 2001, Dec-20, Volume: 345, Issue:25

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Drug Interactions; Drug Therapy, Combination; Humans; Ibuprofen; Isoenzymes; Lactones; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Sulfones; Thromboxane B2

2001
Valdecoxib does not impair platelet function.
    The American journal of emergency medicine, 2002, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Bleeding Time; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Naproxen; Platelet Aggregation; Statistics, Nonparametric; Sulfonamides; Thromboxane B2

2002
Effects of cyclooxygenases inhibitors on vasoactive prostanoids and thrombin generation at the site of microvascular injury in healthy men.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Jun-01, Volume: 23, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Endothelium, Vascular; Fibrinolytic Agents; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Naproxen; Prostaglandin-Endoperoxide Synthases; Sulfones; Thrombin; Thromboxane B2

2003
Lumiracoxib: pharmacokinetic and pharmacodynamic profile when coadministered with fluconazole in healthy subjects.
    Journal of clinical pharmacology, 2004, Volume: 44, Issue:2

    Topics: Adult; Antifungal Agents; Area Under Curve; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Female; Fluconazole; Humans; Isoenzymes; Male; Membrane Proteins; Organic Chemicals; Prostaglandin-Endoperoxide Synthases; Thromboxane B2

2004
Lumiracoxib does not affect the ex vivo antiplatelet aggregation activity of low-dose aspirin in healthy subjects.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:10

    Topics: Adolescent; Adult; Arachidonic Acid; Aspirin; Collagen; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Epoprostenol; Female; Humans; Male; Middle Aged; Organic Chemicals; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2

2005
Effect of 3 g of intravenous paracetamol on post-operative analgesia, platelet function and liver enzymes in patients undergoing tonsillectomy under local anaesthesia.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:9

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glutathione Transferase; Humans; Liver; Male; Pain Measurement; Pain, Postoperative; Platelet Aggregation; Prospective Studies; Statistics, Nonparametric; Thromboxane B2; Time Factors; Tonsillectomy

2007
Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Double-Blind Method; Etoricoxib; Female; Humans; Male; Middle Aged; Pyrazoles; Pyridines; Sulfonamides; Sulfones; Thromboxane B2

2008
The interaction of ibuprofen and diclofenac with aspirin in healthy volunteers.
    British journal of pharmacology, 2009, Volume: 157, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Delayed-Action Preparations; Diclofenac; Drug Interactions; Female; Humans; Ibuprofen; Male; Middle Aged; Platelet Aggregation; Risk Factors; Thromboxane B2

2009
Systemic bioavailability of topical diclofenac sodium gel 1% versus oral diclofenac sodium in healthy volunteers.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Cross-Over Studies; Diclofenac; Dinoprostone; Female; Humans; Male; Middle Aged; Platelet Aggregation; Tablets, Enteric-Coated; Thromboxane B2

2010

Other Studies

24 other study(ies) available for diclofenac and thromboxane b2

ArticleYear
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Aug-05, Volume: 100, Issue:16

    Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors

2003
Efflux of cyclic AMP, prostaglandin E2 and F2 alpha and thromboxane B2 in leg lymph of rabbits after scalding injury.
    Acta physiologica Scandinavica, 1979, Volume: 107, Issue:4

    Topics: Animals; Burns; Cyclic AMP; Diclofenac; Hindlimb; Indomethacin; Lymph; Prostaglandins E; Prostaglandins F; Rabbits; Thromboxane B2; Thromboxanes; Time Factors

1979
Anti-inflammatory activity of BF389, a Di-T-butylphenol, in animal models of arthritis.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis, Experimental; Collagen; Diamines; Diclofenac; Dinoprostone; Disease Models, Animal; Female; Interleukin-1; Leukotriene B4; Male; Naproxen; Oxazines; Phenols; Piroxicam; Rats; Rats, Inbred Lew; Thromboxane B2

1992
The effects of modulation of prostanoid metabolism on the thoracic platelet accumulation induced by intravenous administration of collagen in the guinea-pig.
    Thrombosis and haemostasis, 1986, Dec-15, Volume: 56, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Chromium Radioisotopes; Collagen; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Injections, Intravenous; Platelet Aggregation; Platelet Count; Prostaglandins; Pyridines; Thorax; Thromboxane B2; Thromboxanes

1986
Intrathoracic platelet accumulation in the guinea-pig induced by intravenous administration of arachidonic acid--effect of cyclooxygenase and thromboxane synthetase inhibitors.
    Thrombosis and haemostasis, 1986, Dec-15, Volume: 56, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Chromium Radioisotopes; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Fibrinogen; Guinea Pigs; Injections, Intravenous; Iodine Radioisotopes; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Pulmonary Circulation; Thorax; Thromboxane B2; Thromboxane-A Synthase

1986
The effect of prostaglandin synthesis inhibition on motility of the sheep ureter.
    Acta physiologica Scandinavica, 1987, Volume: 131, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Diclofenac; Dinoprost; Humans; Indomethacin; Muscle Contraction; Muscle, Smooth; Prostaglandins F; Sheep; Thromboxane B2; Ureter

1987
Comparison of the effects of different anti-inflammatory drugs on synovial fluid prostanoid concentrations in patients with rheumatoid arthritis.
    Clinical rheumatology, 1985, Volume: 4, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Dinoprostone; Guanidines; Humans; Indomethacin; Naproxen; ortho-Aminobenzoates; Prednisolone; Prostaglandins; Prostaglandins E; Quinazolines; Synovial Fluid; Thromboxane B2

1985
Effects of Voltaren on arachidonic acid metabolism in arthritis patients.
    Agents and actions. Supplements, 1985, Volume: 17

    Topics: Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Metabolic Clearance Rate; Osteoarthritis; Prostaglandins E; Synovial Fluid; Thromboxane B2

1985
Effects of stroma-free hemoglobin solutions on pulmonary vascular resistance and mediator release in the isolated perfused rabbit lung.
    Shock (Augusta, Ga.), 1994, Volume: 1, Issue:2

    Topics: Animals; Azepines; Catalase; Cattle; Deferoxamine; Diclofenac; Female; Free Radical Scavengers; Hemoglobins; Histamine Release; Iron; Male; Perfusion; Platelet Activating Factor; Pulmonary Circulation; Rabbits; Stimulation, Chemical; Thromboxane B2; Triazoles; Vascular Resistance; Vasoconstriction

1994
Mechanisms of 3-carene-induced bronchoconstriction in the isolated guinea pig lung.
    Respiration; international review of thoracic diseases, 1995, Volume: 62, Issue:3

    Topics: Animals; Arachidonic Acid; Bicyclic Monoterpenes; Bronchoconstriction; Carbazoles; Cattle; Cells, Cultured; Diclofenac; Dose-Response Relationship, Drug; Endothelium; Guinea Pigs; In Vitro Techniques; Lung; Male; Monoterpenes; Prostaglandin Antagonists; Pulmonary Artery; Respiratory Mechanics; Terpenes; Thromboxane B2; Time Factors

1995
A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats.
    Gastroenterology, 1995, Volume: 109, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cyclooxygenase Inhibitors; Diclofenac; Gastric Acid; Hematocrit; Male; Misoprostol; Rats; Rats, Wistar; Stomach Ulcer; Thromboxane B2

1995
Effect of some cyclooxygenase inhibitors on the increase in guanosine 3':5'-cyclic monophosphate induced by NO-donors in human whole platelets.
    British journal of pharmacology, 1998, Volume: 123, Issue:7

    Topics: Acetophenones; Aspirin; Blood Platelets; Cyclic GMP; Cyclooxygenase Inhibitors; Diclofenac; Humans; Indomethacin; Indoprofen; Nitric Oxide; Nitroprusside; Penicillamine; Phospholipases A; Thromboxane B2

1998
Endothelin-1 and thromboxane A2 increase pulmonary vascular resistance in granulocyte-mediated lung injury.
    Critical care medicine, 1998, Volume: 26, Issue:11

    Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Female; Granulocytes; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Perfusion; Phenylpropionates; Prospective Studies; Pulmonary Artery; Pyrimidines; Rabbits; Random Allocation; Respiratory Distress Syndrome; Thromboxane A2; Thromboxane B2; Vascular Resistance

1998
Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bradykinin; Coronary Disease; Coronary Vessels; Cyclooxygenase Inhibitors; Diclofenac; Dogs; Dose-Response Relationship, Drug; Hyperemia; Male; Myocardium; Nitric Oxide Synthase; Nitroarginine; Salicylic Acid; Thromboxane B2; Time Factors

1999
Comparison of inhibitory effects of meloxicam and diclofenac on human thromboxane biosynthesis after single doses and at steady state.
    Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:5

    Topics: Administration, Oral; Adult; Area Under Curve; Cyclooxygenase Inhibitors; Diclofenac; Humans; Male; Meloxicam; Reference Values; Therapeutic Equivalency; Thiazines; Thiazoles; Thromboxane B2

1999
Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs.
    British journal of pharmacology, 1999, Volume: 126, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Blood Pressure; Carcinoma; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salicylates; Substrate Specificity; Sulfonamides; Sulindac; Thromboxane B2; Tumor Cells, Cultured

1999
Exercise enhances vasorelaxation in experimental obesity associated hypertension.
    Cardiovascular research, 1999, Volume: 43, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Analysis of Variance; Animals; Blood Glucose; Carotid Arteries; Cholesterol; Cyclooxygenase Inhibitors; Diclofenac; Endothelium, Vascular; Hypertension; In Vitro Techniques; Insulin; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Obesity; Physical Exertion; Rats; Rats, Zucker; Thromboxane B2; Triglycerides; Vasodilation; Vasodilator Agents

1999
Effects of selective and unselective cyclooxygenase inhibitors on prostanoid release from various rat organs.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dose-Response Relationship, Drug; Ketorolac; Kidney; Lung; Male; Meloxicam; Nitrobenzenes; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiazines; Thiazoles; Thromboxane B2

2000
Effects of diclofenac in the rat tail ischaemia--reperfusion injury model of acute hyperalgesia.
    Pain, 2001, Volume: 89, Issue:2-3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Brain Chemistry; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Hyperalgesia; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury; Tail; Thromboxane B2

2001
Pharmacokinetics of diclofenac and inhibition of cyclooxygenases 1 and 2: no relationship to the CYP2C9 genetic polymorphism in humans.
    British journal of clinical pharmacology, 2003, Volume: 55, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; Dinoprostone; Genotype; Humans; Isoenzymes; Male; Membrane Proteins; Middle Aged; Polymorphism, Genetic; Prostaglandin-Endoperoxide Synthases; Thromboxane B2

2003
Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2.
    British journal of pharmacology, 2005, Volume: 144, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Biological Availability; Blood Platelets; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Disease Models, Animal; Drug Evaluation, Preclinical; Edema; Female; Fever; Fibroblasts; Humans; Hyperalgesia; Male; Membrane Proteins; Organic Chemicals; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Skin; Thromboxane B2

2005
Characterization of inhibition of platelet function by paracetamol and its interaction with diclofenac in vitro.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandin-Endoperoxide Synthases; Thromboxane B2

2005
Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung.
    Prostaglandins, leukotrienes, and essential fatty acids, 2008, Volume: 78, Issue:2

    Topics: Animals; Bronchoconstriction; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Flurbiprofen; Guinea Pigs; Humans; Leukotrienes; Lung; Male; Ovalbumin; Piperazines; Prostaglandins; Pyrazoles; Sulfonamides; Thiazoles; Thromboxane A2; Thromboxane B2

2008
Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo.
    Journal of thrombosis and haemostasis : JTH, 2009, Volume: 7, Issue:10

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Cells, Cultured; Chlorides; Cricetinae; Cyclooxygenase Inhibitors; Diclofenac; Endothelium, Vascular; Ferric Compounds; Humans; Mesocricetus; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Platelet Activation; Platelet Adhesiveness; Skin Window Technique; Thromboplastin; Thrombosis; Thromboxane B2; Tumor Necrosis Factor-alpha

2009