diclofenac and sulindac

diclofenac has been researched along with sulindac in 57 studies

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-199016 (28.07)18.7374
1990's12 (21.05)18.2507
2000's11 (19.30)29.6817
2010's17 (29.82)24.3611
2020's1 (1.75)2.80

Authors

AuthorsStudies
Graves, P; Kuze, K; Leahy, A; Stuhlmann, H; Wilson, P; You, G1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Barreiro, EJ; Fraga, CA; Lima, LM; Romeiro, NC; Sant'Anna, CM1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Horie, T; Horiguchi, A; Kitamura, S; Kotake, Y; Ohshita, H; Ohta, S; Sanoh, S; Sugihara, K; Tateno, C; Tayama, Y1
Kumar, M; Sinha, VR; Thareja, S1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Akgul, O; Alfawaz Altamimi, AS; Angeli, A; Bartolucci, G; Carta, F; Di Cesare Mannelli, L; Ghelardini, C; Scozzafava, A; Supuran, CT; Vullo, D1
Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K1
Burdeĭnyĭ, AP1
Pemberton, RE; Strand, LJ1
Baumgartner, H1
Abe, K; Akiu, N; Saito, T; Sato, M; Takeuchi, K; Yasujima, M; Yoshinaga, K1
de Pouvourville, G1
Brooks, PM; Johnston, HJ; Kelly, D; Monaghan, JC; Okoro, EO; Stokes, GS1
Abe, K; Sato, K; Sato, M; Takeuchi, K; Tanno, M; Yasujima, M; Yoshinaga, K1
Montenegro, MA; Palomino, H1
Blass, A; Carloni, C; Filipponi, P; Grossi, E; Hruska, KA; Mannarelli, C; Moretti, I; Morucci, P; Pacifici, R; Tini, S1
de Jong, PE; de Zeeuw, D; Donker, AJ; Pratt, JJ; van der Hem, GK; Vriesendorp, R1
Altman, R1
Gribnau, FW; Koopmans, PP; Thien, T1
Harima, Y; Koshiro, A; Maekawa, T; Miyauchi, Y; Sakabe, T; Tsutsui, T1
Blake, JW; Tobin, T; Weckman, T; Woods, WE1
Macauley, D1
Minker, E; Végh, A1
Guobis, G; Iushenaite, Ia1
Obel, AO1
Nahir, AM; Scharf, Y1
Pathy, MS1
Paolaggi, JB1
Backman, EA; Beckman, EA; Kulling, PE; Skagius, AS1
Carson, JL; Manoukian, AV1
Caldwell, J; Kenna, JG; Wade, LT1
Tolman, KG1
Russeva, VN; Zhivkova, ZD1
Giuliano, F; Warner, TD1
Bhagat, K1
Brooks, G; Crabbe, MJ; Harper, JV; Shattock, MJ; Wang, Y; Yu, XM1
Dargan, PI; Jones, AL; O'Connor, N1
Hartnell, NR; Wilson, JP1
Bass, SE; Cheng, RY; Del Soldato, P; Macdonald, CJ; Moody, TW; Roberts, DD; Sienkiewicz, P; Sparatore, A; Wink, DA; Yeh, GC1
Brünnert, D; Bruns, I; Cadeddu, RP; Czibere, A; Fröbel, J; Haas, R; Hartwig, S; Lehr, S; Prenzel, T; Schroeder, T; Singh, R; Wilk, CM; Zerbini, LF1
Bhasin, M; Cordeiro, J; Correa, RG; Czibere, A; Fisher, PB; Gu, X; Li, L; Libermann, TA; Sarkar, D; Simabuco, FM; Tamura, RE; Wang, Y; Zerbini, LF; Zhou, JR1
Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC1
Honda, H; Ito, Y; Kawamoto, T; Morita, O1

Reviews

7 review(s) available for diclofenac and sulindac

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Drug therapy of ankylosing spondyloarthritis (Bechterew's disease)].
    Terapevticheskii arkhiv, 1978, Volume: 50, Issue:12

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Apazone; Butadienes; Cyclophosphamide; Diclofenac; Drug Combinations; Drug Evaluation; Glycolates; Gold; Humans; Ibuprofen; Indomethacin; Ketoprofen; Levamisole; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates; Spondylitis, Ankylosing; Sulindac

1978
[Pharmacodynamics and adverse effects of modern nonsteroid anti-inflammatory agents].
    Terapevticheskii arkhiv, 1981, Volume: 53, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Eruptions; Drug Interactions; Female; Gastrointestinal Diseases; Headache; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Sulindac

1981
Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs.
    East African medical journal, 1982, Volume: 59, Issue:6

    Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Diclofenac; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Phenylbutyrates; Piroxicam; Propionates; Sulindac; Thiazines

1982
Nonsteroidal anti-inflammatory drug-induced hepatic disorders. Incidence and prevention.
    Drug safety, 1996, Volume: 15, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chemical and Drug Induced Liver Injury; Cohort Studies; Diclofenac; Humans; Incidence; Indomethacin; Liver; Liver Diseases; Naproxen; Oxaprozin; Phenylbutazone; Propionates; Risk Factors; Sulindac

1996
Hepatotoxicity of non-narcotic analgesics.
    The American journal of medicine, 1998, Jul-27, Volume: 105, Issue:1B

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Diclofenac; Humans; Liver Diseases; Risk Factors; Salicylates; Sulindac

1998
Hepatocellular damage from non-steroidal anti-inflammatory drugs.
    QJM : monthly journal of the Association of Physicians, 2003, Volume: 96, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Liver Injury; Diclofenac; Disease Susceptibility; Drug Hypersensitivity; Female; Humans; Liver Diseases; Liver Failure, Acute; Middle Aged; Mitochondria, Liver; Risk Factors; Sulindac

2003

Trials

9 trial(s) available for diclofenac and sulindac

ArticleYear
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.
    Digestive diseases and sciences, 1979, Volume: 24, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin

1979
[A clinical comparison of sulindac and diclofenac in the treatment of osteoarthritis (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1979, Jul-10, Volume: 68, Issue:28

    Topics: Adult; Aged; Diclofenac; Double-Blind Method; Female; Humans; Indenes; Male; Middle Aged; Osteoarthritis; Phenylacetates; Sulindac

1979
The effects of sulindac and diclofenac in essential hypertension controlled by treatment with a beta blocker and/or diuretic.
    Clinical and experimental hypertension. Part A, Theory and practice, 1991, Volume: 13, Issue:6-7

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Creatinine; Diclofenac; Diuretics; Double-Blind Method; Drug Interactions; Female; Humans; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Sulindac

1991
No adverse effect of non-steroidal anti-inflammatory drugs, sulindac and diclofenac sodium, on blood pressure control with a calcium antagonist, nifedipine, in elderly hypertensive patients.
    The Tohoku journal of experimental medicine, 1991, Volume: 165, Issue:3

    Topics: Aged; Blood Pressure; Diclofenac; Dinoprostone; Drug Therapy, Combination; Female; Humans; Hypertension; Kidney; Nifedipine; Sulindac

1991
International experiences with diclofenac in osteoarthritis.
    The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B

    Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Naproxen; Osteoarthritis; Random Allocation; Sulindac

1986
The influence of ibuprofen, diclofenac and sulindac on the blood pressure lowering effect of hydrochlorothiazide.
    European journal of clinical pharmacology, 1987, Volume: 31, Issue:5

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Creatinine; Diclofenac; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Indenes; Male; Middle Aged; Potassium; Renin; Sulindac

1987
[Pharmacodynamics and adverse effects of modern nonsteroid anti-inflammatory agents].
    Terapevticheskii arkhiv, 1981, Volume: 53, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Eruptions; Drug Interactions; Female; Gastrointestinal Diseases; Headache; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Sulindac

1981
A comparative study of diclofenac and sulindac in ankylosing spondylitis.
    Rheumatology and rehabilitation, 1980, Volume: 19, Issue:3

    Topics: Adult; Clinical Trials as Topic; Diclofenac; Female; Humans; Indenes; Male; Middle Aged; Phenylacetates; Spondylitis, Ankylosing; Sulindac

1980
Effects of non-steroidal anti-inflammatory drugs on hypertension control using angiotensin converting enzyme inhibitors and thiazide diuretics.
    East African medical journal, 2001, Volume: 78, Issue:10

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Diclofenac; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Lisinopril; Middle Aged; Osteoarthritis; Sulindac; Treatment Outcome

2001

Other Studies

42 other study(ies) available for diclofenac and sulindac

ArticleYear
Heterologous expression and functional characterization of a mouse renal organic anion transporter in mammalian cells.
    The Journal of biological chemistry, 1999, Jan-15, Volume: 274, Issue:3

    Topics: Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; COS Cells; Glycosylation; Histidine; In Situ Hybridization; Kidney; Kinetics; Mice; p-Aminohippuric Acid; Probenecid; Protein Processing, Post-Translational; Renal Agents; Substrate Specificity; Tunicamycin

1999
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
NSAIDs revisited: putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARgamma).
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalytic Domain; Computational Biology; Drug Design; Ligands; Models, Molecular; PPAR gamma; Protein Conformation; Software

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Animals; Cells, Cultured; Child, Preschool; Chimera; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drugs, Investigational; Female; Half-Life; Hepatocytes; Humans; Immunomagnetic Separation; Liver; Male; Metabolic Clearance Rate; Mice; Mice, SCID; Recombinant Proteins; Species Specificity; Urokinase-Type Plasminogen Activator

2012
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis.
    Journal of medicinal chemistry, 2018, 06-14, Volume: 61, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbonic Anhydrase Inhibitors; Humans; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides

2018
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design.
    Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4

    Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry

2020
Effect of sulindac on prostaglandin synthesis in human and in cultured rat renal and vascular smooth muscle cells.
    The Tohoku journal of experimental medicine, 1992, Volume: 166, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Animals; Arachidonic Acids; Cells, Cultured; Creatinine; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Kidney; Kidney Glomerulus; Male; Middle Aged; Muscle, Smooth, Vascular; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulindac

1992
The economic consequences of NSAID-induced gastropathy: the French context.
    Scandinavian journal of rheumatology. Supplement, 1992, Volume: 96

    Topics: Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Cost of Illness; Diclofenac; Duodenal Ulcer; Economics, Hospital; Etodolac; France; Gastrointestinal Diseases; Humans; Ketoprofen; Naproxen; National Health Programs; Piroxicam; Rheumatic Diseases; Sulindac

1992
Induction of cleft palate in mice by inhibitors of prostaglandin synthesis.
    Journal of craniofacial genetics and developmental biology, 1990, Volume: 10, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cleft Palate; Diclofenac; Female; Indomethacin; Injections, Intramuscular; Maternal-Fetal Exchange; Mice; Microscopy; Naproxen; Organ Culture Techniques; Palate; Pregnancy; Sulindac

1990
Evidence for a prostaglandin-mediated bone resorptive mechanism in subjects with fasting hypercalciuria.
    Calcified tissue international, 1988, Volume: 43, Issue:2

    Topics: Adolescent; Adult; Bone Resorption; Calcium; Diclofenac; Female; Humans; Male; Metabolic Diseases; Middle Aged; Parathyroid Hormone; Prostaglandins; Sulindac

1988
Reduction of urinary protein and prostaglandin E2 excretion in the nephrotic syndrome by non-steroidal anti-inflammatory drugs.
    Clinical nephrology, 1986, Volume: 25, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Diclofenac; Dinoprostone; Flurbiprofen; Glomerular Filtration Rate; Humans; Indomethacin; Male; Middle Aged; Nephrotic Syndrome; Prostaglandins E; Proteinuria; Renin; Sulindac

1986
Intoxication with sulindac, tiaramide hydrochloride and diclofenac sodium.
    Intensive care medicine, 1987, Volume: 13, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Diclofenac; Female; Hemoperfusion; Humans; Piperazines; Suicide, Attempted; Sulindac

1987
Effects of phenylbutazone and oxyphenbutazone on acidic drug detection in high performance thin layer chromatographic systems.
    Journal of pharmacological methods, 1986, Volume: 16, Issue:4

    Topics: Animals; Chromatography, Thin Layer; Diclofenac; Female; Fenoprofen; Horses; Hydrogen-Ion Concentration; Ibuprofen; Oxyphenbutazone; Pharmaceutical Preparations; Phenylbutazone; Piroxicam; Sulindac

1986
Worldwide experience with diclofenac in rheumatoid arthritis and osteoarthritis.
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2 Suppl 1

    Topics: Arthritis, Rheumatoid; Aspirin; Diclofenac; Double-Blind Method; Humans; Indomethacin; Naproxen; Osteoarthritis; Sulindac; Tolmetin

1985
Ganglionic blocking effect of indomethacin and other prostaglandin synthetase inhibitors.
    Acta physiologica Academiae Scientiarum Hungaricae, 1980, Volume: 55, Issue:3

    Topics: Animals; Cats; Diclofenac; Fenoprofen; Ganglia, Sympathetic; In Vitro Techniques; Indomethacin; Niflumic Acid; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Rana esculenta; Sulindac; Synaptic Transmission

1980
Osteoarthritis and non-steroidal and anti-inflammatory drugs: a multi-centre comparative study.
    Current medical research and opinion, 1982, Volume: 7, Issue:Suppl 1

    Topics: Aged; Diclofenac; Female; Hip Joint; Humans; Ibuprofen; Indenes; Knee Joint; Male; Naproxen; Osteoarthritis; Sulindac

1982
[New non-steroidal anti-inflammatory agents].
    La Revue du praticien, 1980, Apr-21, Volume: 30, Issue:23

    Topics: Adult; Anti-Inflammatory Agents; Child; Diclofenac; Female; Humans; Male; ortho-Aminobenzoates; Phenothiazines; Phenylbutyrates; Pregnancy; Propionates; Pyrazoles; Sulindac

1980
Renal impairment after acute diclofenac, naproxen, and sulindac overdoses.
    Journal of toxicology. Clinical toxicology, 1995, Volume: 33, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Adult; Alcoholic Intoxication; Creatinine; Diclofenac; Drug Interactions; Female; Humans; Male; Middle Aged; Naproxen; Sulindac

1995
Immunochemical identification of mouse hepatic protein adducts derived from the nonsteroidal anti-inflammatory drugs diclofenac, sulindac, and ibuprofen.
    Chemical research in toxicology, 1997, Volume: 10, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Ibuprofen; Immune Sera; Immunoblotting; Immunochemistry; Liver; Mice; Mice, Inbred Strains; Proteins; Rabbits; Sulindac

1997
Protein binding of some nonsteroidal anti-inflammatory drugs studied by high-performance liquid affinity chromatography.
    International journal of pharmaceutics, 1999, Mar-25, Volume: 180, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Chromatography, High Pressure Liquid; Diclofenac; Indomethacin; Protein Binding; Serum Albumin; Sulindac

1999
Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs.
    British journal of pharmacology, 1999, Volume: 126, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Blood Pressure; Carcinoma; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salicylates; Substrate Specificity; Sulfonamides; Sulindac; Thromboxane B2; Tumor Cells, Cultured

1999
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit vascular smooth muscle cell proliferation via differential effects on the cell cycle.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Cell Division; Cell Line; Diclofenac; Dose-Response Relationship, Drug; Flow Cytometry; Ibuprofen; Indomethacin; Muscle, Smooth, Vascular; Rats; Sodium Salicylate; Sulindac

2003
Replication of the Weber effect using postmarketing adverse event reports voluntarily submitted to the United States Food and Drug Administration.
    Pharmacotherapy, 2004, Volume: 24, Issue:6

    Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Diflunisal; Epidemiologic Measurements; Flurbiprofen; Humans; Incidence; Piroxicam; Retrospective Studies; Sulindac; Time Factors; United Kingdom; United States; United States Food and Drug Administration

2004
Novel dithiolethione-modified nonsteroidal anti-inflammatory drugs in human hepatoma HepG2 and colon LS180 cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Mar-15, Volume: 15, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Cell Line, Tumor; Colorectal Neoplasms; Cytochrome P-450 CYP1A1; Diclofenac; Humans; Liver Neoplasms; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Messenger; Sulindac; Thiones

2009
The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Cell Cycle Proteins; Cell Differentiation; Cell Survival; Cloning, Molecular; Diclofenac; Flow Cytometry; Fos-Related Antigen-2; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Vectors; HL-60 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia, Myeloid, Acute; Nuclear Proteins; Proto-Oncogene Proteins c-jun; RNA Interference; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulindac; Transcription Factor AP-1; Transcriptional Activation

2011
Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Diclofenac; Drug Synergism; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukins; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mice; Mice, SCID; NF-kappa B; Nuclear Proteins; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sesquiterpenes; Sulindac; Tumor Burden; Xenograft Model Antitumor Assays

2011
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts

2012
Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:4

    Topics: Administration, Oral; Animals; Chlorpromazine; Cholestasis; Cholesterol; Cyclosporine; Diclofenac; Dose-Response Relationship, Drug; Flutamide; Gene Expression; Humans; Imipramine; Inflammation; Ketoconazole; Liver; Methyltestosterone; Oxidative Stress; Rats; Risk Assessment; Sulindac; Tamoxifen; Toxicogenetics

2017