diclofenac has been researched along with sulfasalazine in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (5.13) | 18.2507 |
| 2000's | 12 (30.77) | 29.6817 |
| 2010's | 23 (58.97) | 24.3611 |
| 2020's | 2 (5.13) | 2.80 |
| Authors | Studies |
|---|---|
| Faller, B; Wohnsland, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Board, PG; Christ, AN; Clark, AG; Flanagan, JU; Hall, R; Hayes, JD; Hume, DA; Oakley, AJ; Smythe, ML; Weber, JE | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Campillo, NE; Cañada, FJ; Canales, A; Carvalho, I; Chierrito, TPC; Martinez, A; Martínez-Gonzalez, L; Pedersoli-Mantoani, S; Perez, C; Pérez, DI; Roca, C; Sebastian-Pérez, V | 1 |
| Abu-Serie, MM; AlFadly, ED; Bakkar, NZ; Bartolini, M; Belal, ASF; El-Yazbi, AF; Elkazaz, S; Elzahhar, PA; Ghareeb, DA; Iriepa, I; Janockova, J; Kobeissy, F; Moraleda, I; Rafeh, RW; Saudi, MNS; Shaltout, H; Soukup, O; Tramarin, A | 1 |
| DeRose, EF; Duff, MR; Gabel, SA; Howell, EE; Krahn, JM; London, RE; Pedersen, LC | 1 |
| Balliano, TL; Barbosa, G; Carvalho, VF; da Silva, BA; de Souza, ET; Lima, LM; Martins, IRR; Martins, MA; Medeiros, MM; Moraes Junior, MO; Nunes, IKDC; Silva, PMR; Silva, SWD | 1 |
| Barbosa, G; Ceschi, MA; Dantas, RF; Dardenne, LE; de Salles, CMC; Guedes, IA; Lima, LM; Lopes, JPB; Lüdtke, DS; Ruaro, TC; Senger, MR; Silva, L; Silva-Jr, FP; Zimmer, AR | 1 |
| Calin, A; Elswood, J | 1 |
| Dawes, PT; Dziedzic, K; Layton, MA | 1 |
| Chesner, IM; Michell, NP; Routledge, H | 1 |
| Ardicoglu, A; Ardicoglu, O; Kiris, A; Kocakoc, E; Ozgocmen, S | 1 |
| Kandefer-Szerszeń, M; Majdan, M; Parada-Turska, J; Rzeski, W; Turski, WA | 1 |
| Feng, XH; He, YT; Lin, SQ; Liu, W; Lü, AP; Lü, C; Qian, X; Song, YJ; Su, L; Yan, XP; Zeng, SP; Zha, QL; Zhu, WH | 1 |
| Abe, N; Hatakeyama, M; Hayashi, Y; Inoue, K; Nakai, Y; Ohta, KY; Otagiri, M; Yuasa, H | 1 |
| Feng, X; He, Y; Liu, W; Lu, A; Lu, C; Qian, X; Song, Y; Su, L; Yan, X; Zeng, S; Zha, Y; Zhu, W | 1 |
| He, Y; Lu, A; Tsang, I; Zha, Y | 1 |
| Akar, S; Akkoc, N; Birlik, M; Onen, F; Sari, I | 1 |
| Lal, R; Pilgrim, S; Tsiamis, A; Velchuru, V; Waters, G | 1 |
| He, Y; Jiang, M; Lu, A; Zha, Q; Zhao, J | 1 |
| Abramovitch, R; Corchia, N; Edrei, Y; Gross, E | 1 |
| Appelbaum, L; Breuer, S; Hubert, A; Maimon, O; Peretz, T | 1 |
| Abramovitch, R; Corchia, N; Dery, E; Fried, I; Gross, E; Komar-Stossel, C; Meir, K | 1 |
| Basit, AW; Gonsalves, AM; Murdan, S; Serra, AC; Veiga, FJ; Vieira, AC | 2 |
1 review(s) available for diclofenac and sulfasalazine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
4 trial(s) available for diclofenac and sulfasalazine
| Article | Year |
|---|---|
[Predictive role of diagnostic information in treatment efficacy of rheumatoid arthritis based on neural network model analysis].
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Diclofenac; Drugs, Chinese Herbal; Female; Humans; Male; Medicine, Chinese Traditional; Methotrexate; Middle Aged; Neural Networks, Computer; Phytotherapy; Sulfasalazine; Treatment Outcome | 2007 |
Correlations between symptoms as assessed in traditional chinese medicine (TCM) and ACR20 efficacy response: a comparison study in 396 patients with rheumatoid arthritis treated with TCM or Western medicine.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Medicine, Chinese Traditional; Methotrexate; Middle Aged; Single-Blind Method; Sulfasalazine; Treatment Outcome | 2007 |
Differential effect on symptoms treated with traditional Chinese medicine and western combination therapy in RA patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Diclofenac; Drug Therapy, Combination; Drugs, Chinese Herbal; Endpoint Determination; Female; Humans; Male; Methotrexate; Middle Aged; Single-Blind Method; Sulfasalazine | 2008 |
Does gastrointestinal adverse drug reaction influence therapeutic effect in the treatment of rheumatoid arthritis?
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Diclofenac; Drug Therapy, Combination; Drugs, Chinese Herbal; Gastrointestinal Diseases; Humans; Methotrexate; Sulfasalazine; Treatment Outcome | 2010 |
34 other study(ies) available for diclofenac and sulfasalazine
| Article | Year |
|---|---|
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase.
Topics: Binding Sites; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glutathione Transferase; Hematopoiesis; Humans; Intramolecular Oxidoreductases; Lipocalins; Models, Molecular; Molecular Conformation; Nocodazole | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Indoles; Molecular Structure; Piperidines; Structure-Activity Relationship | 2018 |
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
Topics: Acetylcholine; Alzheimer Disease; Animals; Cell Line; Cholinesterase Inhibitors; Cyclooxygenase 2 Inhibitors; Drug Design; Humans; Inflammation; Lipoxygenase Inhibitors; Mice; Molecular Docking Simulation; Neurons; PC12 Cells; Rats; Semicarbazides; Triazoles | 2019 |
The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Crystallography, X-Ray; Drug Design; Folic Acid; Folic Acid Antagonists; Humans; Models, Molecular; Tetrahydrofolate Dehydrogenase | 2020 |
Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies.
Topics: Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Design; Enzyme Inhibitors; Humans; Hydrazones; Hypersensitivity; Lung; Male; Mice | 2020 |
Synthesis of new lophine-carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling.
Topics: | 2019 |
A prospective nationwide cross-sectional study of NSAID usage in 1331 patients with ankylosing spondylitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cross-Sectional Studies; Diclofenac; Female; Gold; Humans; Ibuprofen; Male; Methotrexate; Middle Aged; Naproxen; Penicillamine; Piroxicam; Prednisolone; Prospective Studies; Spondylitis, Ankylosing; Sulfasalazine; United Kingdom | 1990 |
Sacroiliitis in an HLA B27-negative patient following giardiasis.
Topics: Adult; Animals; Arthritis, Reactive; Blood Sedimentation; Diclofenac; Giardia lamblia; Giardiasis; HLA-B27 Antigen; Humans; Jejunum; Male; Metronidazole; Sacroiliac Joint; Sulfasalazine | 1998 |
A case of intestinal obstruction.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Diclofenac; Drug Combinations; Female; Humans; Intestinal Obstruction; Sulfasalazine | 2000 |
Paravertebral abscess formation due to brucellosis in a patient with ankylosing spondylitis.
Topics: Abscess; Adult; Anti-Bacterial Agents; Brucella; Brucellosis; Diclofenac; Doxycycline; Drug Therapy, Combination; Humans; Lumbosacral Region; Magnetic Resonance Imaging; Male; Muscle, Skeletal; Myositis; Osteomyelitis; Spondylitis, Ankylosing; Streptomycin; Sulfasalazine; Trimethoprim, Sulfamethoxazole Drug Combination | 2001 |
Effect of glutamate receptor antagonists and antirheumatic drugs on proliferation of synoviocytes in vitro.
Topics: Animals; Antirheumatic Agents; Benzodiazepines; Benzodiazepinones; Celecoxib; Cell Line; Cell Proliferation; Cell Survival; Diclofenac; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Inhibitory Concentration 50; Methotrexate; Naproxen; Pyrazoles; Quinoxalines; Sulfasalazine; Sulfonamides; Synovial Membrane | 2006 |
Functional characterization of human proton-coupled folate transporter/heme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Biological Transport, Active; Cell Line; Cell Membrane; Diclofenac; Dose-Response Relationship, Drug; Folic Acid; Green Fluorescent Proteins; Humans; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Membrane Transport Proteins; Methotrexate; Microscopy, Confocal; Nigericin; Proton-Coupled Folate Transporter; Sulfasalazine; Transfection | 2007 |
M694V mutation may have a role in susceptibility to ankylosing spondylitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Diclofenac; Drug Combinations; Female; Follow-Up Studies; Genetic Predisposition to Disease; Glucosamine; Gout Suppressants; Homozygote; Humans; Inflammation; Male; Mutation; Radiography; Spondylitis, Ankylosing; Sulfasalazine; Time Factors; Treatment Outcome; Young Adult | 2009 |
Diaphragm disease and small bowel enteropathy due to nonsteroidal anti-inflammatory drugs: a surgical perspective.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Constriction, Pathologic; Diaphragm; Diclofenac; Female; Humans; Intestinal Diseases; Intestinal Mucosa; Intestinal Obstruction; Intestine, Small; Male; Mesalamine; Middle Aged; Sulfasalazine; Treatment Outcome | 2011 |
Improved efficacy of a novel anti-angiogenic drug combination (TL-118) against colorectal-cancer liver metastases; MRI monitoring in mice.
Topics: Angiogenesis Inhibitors; Animals; Cimetidine; Colorectal Neoplasms; Cyclophosphamide; Diclofenac; Disease Progression; Drug Combinations; Humans; Liver Neoplasms; Magnetic Resonance Imaging; Male; Mice; Nitric Oxide; Sulfasalazine | 2012 |
TL-118-anti-angiogenic treatment in pancreatic cancer: a case report.
Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Cyclophosphamide; Deoxycytidine; Diclofenac; Drug Combinations; Female; Gemcitabine; Humans; Middle Aged; Neovascularization, Pathologic; Pancreatic Neoplasms; Sulfasalazine; Tomography, X-Ray Computed | 2013 |
TL-118 and gemcitabine drug combination display therapeutic efficacy in a MYCN amplified orthotopic neuroblastoma murine model--evaluation by MRI.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cimetidine; Cyclophosphamide; Deoxycytidine; Diclofenac; Drug Administration Schedule; Drug Combinations; Drug Synergism; Gemcitabine; Gene Amplification; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Male; Mice, Inbred NOD; Mice, SCID; N-Myc Proto-Oncogene Protein; Neovascularization, Pathologic; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Platelet Endothelial Cell Adhesion Molecule-1; Sulfasalazine; Treatment Outcome; Tretinoin; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Influence of feeding regimens on rat gut fluids and colonic metabolism of diclofenac-β-cyclodextrin.
Topics: Animals; beta-Cyclodextrins; Colon; Diclofenac; Diet; Drug Stability; Fasting; Gastrointestinal Absorption; Gastrointestinal Transit; Hydrogen-Ion Concentration; Male; Prodrugs; Rats, Wistar; Sulfasalazine | 2014 |
Diclofenac-β-cyclodextrin for colonic drug targeting: In vivo performance in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Colon; Diclofenac; Drug Delivery Systems; Drug Liberation; Intestinal Absorption; Male; Prodrugs; Rats, Wistar; Sulfasalazine | 2016 |