diclofenac has been researched along with pyrroles in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rainsford, KD; Whitehouse, MW | 1 |
| Dow, RJ; Gough, KJ; MacDonald, FC; Nicoll, RA | 1 |
| Abe, C; Akita, S; Hirose, S | 1 |
| Tavella, A; Ursini, G | 1 |
| Dannhardt, G; Fiebich, B; Kiefer, W; Krämer, G; Maehrlein, S; Nowe, U | 1 |
| Dobrilla, G | 1 |
| Chiloiro, M; Montanaro, S; Riezzo, G | 1 |
| Alexandova, A; Kesiova, M; Kirkova, M; Todorov, S | 1 |
| Grime, K; Riley, RJ; Webborn, PJ | 1 |
| Barceló, D; Jelić, A; Petrović, M | 1 |
| Kumar, VL; Wahane, VD | 1 |
| Barsoum, FF | 1 |
| Chakravarthi, S; Haleagrahara, N; Judson, JP; Segarra, I; Tan, JR | 1 |
| Choo, YW; Fernández, C; Lim, SH; Mariño, EL; Modamio, P; Ooi, IH; Segarra, I; Tan, SY; Tiew, AL; Wong, MM | 1 |
| Chee, EL; Chee, YL; Chew, CC; Fernández, C; Koo, TW; Liew, MH; Mariño, EL; Modamio, P; Ng, S; Segarra, I | 1 |
| Poorvashree, J; Suneela, D | 1 |
| Bijev, AT; Kostadinov, I; Vladimirova, S; Zlatanova, H | 1 |
3 trial(s) available for diclofenac and pyrroles
| Article | Year |
|---|---|
Psychomotor effects of ketorolac in comparison with buprenorphine and diclofenac.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Attention; Automobile Driving; Buprenorphine; Diclofenac; Flicker Fusion; Humans; Ketorolac; Male; Memory, Short-Term; Psychomotor Performance; Pyrroles; Reaction Time; Time Factors; Tolmetin | 1989 |
[A clinical study on the anti-inflammatory activity and gastrointestinal tolerability of amtolmetin guacyl, a new NSAID, compared with diclofenac in aged patients with osteoarticular diseases].
Topics: Administration, Oral; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Data Interpretation, Statistical; Diclofenac; Drug Tolerance; Female; Gastric Mucosa; Gastroscopy; Glycine; Humans; Intestinal Mucosa; Middle Aged; Monitoring, Physiologic; Osteoarthritis; Pyrroles | 1997 |
Protective effect of amtolmetin guacyl versus placebo diclofenac and misoprostol in healthy volunteers evaluated as gastric electrical activity in alcohol-induced stomach damage.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cross-Over Studies; Diclofenac; Double-Blind Method; Electrophysiology; Ethanol; Gastric Emptying; Gastric Mucosa; Glycine; Humans; Misoprostol; Pyrroles; Stomach | 2001 |
14 other study(ies) available for diclofenac and pyrroles
| Article | Year |
|---|---|
Non-steroid anti-inflammatory drugs: combined assay for anti-edemic potency and gastric ulcerogenesis in the same animal.
Topics: Acacia; Adjuvants, Pharmaceutic; Animals; Aspartic Acid; Aspirin; Carrageenan; Diclofenac; Drug Evaluation, Preclinical; Edema; Female; Glucose; Glycyrrhiza; Male; Phenylacetates; Plants, Medicinal; Pyrroles; Rats; Salicylates; Stomach Ulcer; Tolmetin | 1977 |
Effect of a new antirheumatic drug (CGS10787B) on antibody formation and delayed-type hypersensitivity in BALB/c mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Colony-Forming Units Assay; Cyclophosphamide; Diclofenac; Female; Hypersensitivity, Delayed; Levamisole; Mice; Mice, Inbred BALB C; Pyrroles; T-Lymphocytes | 1988 |
The pyrrole moiety as a template for COX-1/COX-2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Humans; Indomethacin; Isoenzymes; Leukocytes, Mononuclear; Membrane Proteins; Molecular Structure; Monocytes; Neutrophils; Prostaglandin-Endoperoxide Synthases; Pyrroles; Sulfones; Thiophenes | 2000 |
Nitric oxide and non steroidal antiinflammatory drugs (NSAID)-related gastroduodenal damage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gastric Mucosa; Glycine; Humans; Nitric Oxide; Peptic Ulcer; Pyrroles | 2001 |
In vivo effects of amtolmetin guacyl on lipid peroxidation and antioxidant defence systems. Comparison with non-selective and COX-2 selective NSAIDs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Catalase; Celecoxib; Colon; Cyclooxygenase 2 Inhibitors; Diclofenac; Gastric Mucosa; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glycine; Lipid Peroxidation; Liver; Male; Oxyphenonium; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Sulfhydryl Compounds; Sulfonamides; Thiobarbituric Acid Reactive Substances; Tolmetin | 2007 |
Functional consequences of active hepatic uptake on cytochrome P450 inhibition in rat and human hepatocytes.
Topics: Animals; Atorvastatin; Cells, Cultured; Culture Media; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Inhibitors; Estrone; Hepatocytes; Heptanoic Acids; Humans; Hydroxylation; Liver; Midazolam; Pyrroles; Quinolines; Rats; Recombinant Proteins; Tritium | 2008 |
Multi-residue method for trace level determination of pharmaceuticals in solid samples using pressurized liquid extraction followed by liquid chromatography/quadrupole-linear ion trap mass spectrometry.
Topics: Acetaminophen; Atorvastatin; Chromatography, Liquid; Diclofenac; Geologic Sediments; Heptanoic Acids; Hot Temperature; Hydrochlorothiazide; Ibuprofen; Pharmaceutical Preparations; Pyrroles; Reference Standards; Reproducibility of Results; Rivers; Sewage; Solid Phase Extraction; Tandem Mass Spectrometry | 2009 |
Atorvastatin ameliorates inflammatory hyperalgesia in rat model of monoarticular arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Atorvastatin; Diclofenac; Female; Freund's Adjuvant; Heptanoic Acids; Hyperalgesia; Inflammation; Joints; Lower Extremity; Male; Motor Activity; Pyrroles; Rats; Rats, Wistar | 2010 |
Synthesis and molecular modeling studies of anti-inflammatory active 1H-pyrrolizine-5-carboxamides.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Diclofenac; Disease Models, Animal; Edema; Female; Heterocyclic Compounds; Inflammation; Male; Models, Molecular; Pyrroles; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship | 2011 |
Potential protective effect of sunitinib after administration of diclofenac: biochemical and histopathological drug-drug interaction assessment in a mouse model.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspartate Aminotransferases; Blood Urea Nitrogen; Brain; Chemical and Drug Induced Liver Injury; Creatinine; Diclofenac; Drug Interactions; Indoles; Kidney; Liver; Male; Mice; Mice, Inbred ICR; Myocardium; Protective Agents; Protein Kinase Inhibitors; Pyrroles; Spleen; Sunitinib | 2013 |
Sunitinib DDI with paracetamol, diclofenac, mefenamic acid and ibuprofen shows sex-divergent effects on the tissue uptake and distribution pattern of sunitinib in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Diclofenac; Drug Interactions; Female; Ibuprofen; Indoles; Male; Mefenamic Acid; Mice; Mice, Inbred ICR; Pyrroles; Sex Characteristics; Sunitinib; Tissue Distribution | 2016 |
Diclofenac sex-divergent drug-drug interaction with Sunitinib: pharmacokinetics and tissue distribution in male and female mice.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Brain; Diclofenac; Drug Interactions; Female; Indoles; Kidney; Liver; Male; Mice, Inbred ICR; Protein Kinase Inhibitors; Pyrroles; Sex Characteristics; Sunitinib; Tissue Distribution | 2017 |
Novel drug delivery of dual acting prodrugs of hydroxychloroquine with aryl acetic acid NSAIDs: Design, kinetics and pharmacological study.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Carrageenan; Diclofenac; Drug Design; Female; Freund's Adjuvant; Hydroxychloroquine; Inflammation; Male; Mice; Prodrugs; Pyrroles; Rats; Rats, Wistar | 2017 |
In Vivo Evaluation of Anti-inflammatory Activity of 2-[3-Acetyl- 5-(4-chloro-phenyl)-2-methyl-pyrrol-1-yl]-4-methylsulfanylbutyric Acid.
Topics: Animals; Anti-Inflammatory Agents; Butyrates; Carrageenan; Diclofenac; Edema; Foot; Hindlimb; Inflammation; Pyrroles; Rats | 2018 |