diclofenac has been researched along with phenylalanine in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avdeef, A; Tam, KY | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Kimura, T; Masada, M; Nadai, T; Nakanishi, K; Saitoh, H; Yamashita, S | 1 |
| Fisher, MB; Haining, RL; Henne, KR; Jones, JP; Koop, DR; Rettie, AE; Trager, WF | 1 |
| Anderson, DM; Buraglio, M; Crick, N; Shelley, S | 1 |
| Assrir, N; Dansette, PM; Jaouen, M; Jean, P; Mansuy, D; Marques-Soares, C; Melet, A; Pilar Lopez-Garcia, M; Sari, MA | 1 |
| Dansette, PM; Jaouen, M; Johnson, EF; Macherey, AC; Mansuy, D; Marques-Soares, C; Melet, A; Sari, MA; Schoch, GA | 1 |
| Dahiya, R; Pathak, K; Ramadan, WM; Sarpal, AS; Singh, AP | 1 |
1 trial(s) available for diclofenac and phenylalanine
| Article | Year |
|---|---|
A 3-way crossover study to evaluate the pharmacokinetic interaction between nateglinide and diclofenac in healthy volunteers.
Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Cross-Over Studies; Cyclohexanes; Diclofenac; Drug Interactions; Humans; Hypoglycemic Agents; Male; Middle Aged; Nateglinide; Phenylalanine; Reference Values; Time Factors | 2002 |
7 other study(ies) available for diclofenac and phenylalanine
| Article | Year |
|---|---|
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Effects of diclofenac sodium and disodium ethylenediaminetetraacetate on electrical parameters of the mucosal membrane and their relation to the permeability enhancing effects in the rat jejunum.
Topics: Animals; Diclofenac; Edetic Acid; Electrophysiology; In Vitro Techniques; Intestinal Mucosa; Jejunum; Male; Permeability; Phenylalanine; Rats; Rats, Inbred Strains; Sulfanilic Acids | 1987 |
Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding.
Topics: Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Binding Sites; Blotting, Western; Catalysis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Kinetics; Lauric Acids; Leucine; Mutagenesis, Site-Directed; Phenylalanine; Protein Structure, Secondary; Static Electricity; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Sulfaphenazole; Warfarin | 1999 |
Substrate selectivity of human cytochrome P450 2C9: importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid.
Topics: Amino Acids; Anti-Infective Agents; Aryl Hydrocarbon Hydroxylases; Binding Sites; Crystallography, X-Ray; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; Humans; Kinetics; Microsomes; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Software; Spectrophotometry; Substrate Specificity; Sulfaphenazole; Ticrynafen; Time Factors; Ultraviolet Rays; Yeasts | 2003 |
Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants.
Topics: Amiodarone; Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Asparagine; Catalysis; Chromans; Computer Simulation; Cytochrome P-450 CYP2C8; Diclofenac; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Isoleucine; Models, Molecular; Mutagenesis, Site-Directed; Paclitaxel; Phenylalanine; Rabbits; Serine; Substrate Specificity; Sulfonamides; Thiazolidinediones; Tretinoin; Troglitazone | 2004 |
Product development studies of amino acid conjugate of Aceclofenac.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Calorimetry, Differential Scanning; Chromatography, Thin Layer; Crystallography; Diclofenac; Female; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Male; Mass Spectrometry; Particle Size; Phenylalanine; Prodrugs; Rats; Rats, Inbred Strains; Solubility; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stomach; Transition Temperature; X-Ray Diffraction | 2009 |