diclofenac has been researched along with naproxen in 438 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (14.16) | 18.7374 |
| 1990's | 63 (14.38) | 18.2507 |
| 2000's | 117 (26.71) | 29.6817 |
| 2010's | 149 (34.02) | 24.3611 |
| 2020's | 47 (10.73) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Boettcher, I; Elger, W; Kirsch, G; Siegmund, F; Wachtel, H | 1 |
| Casler, JJ; Collins, PW; Gregory, SA; Isakson, PC; Khanna, IK; Koboldt, CM; Koszyk, FJ; Masferrer, JL; Perkins, WE; Seibert, K; Veenhuizen, AW; Weier, RM; Xu, XD; Yu, Y; Zhang, YY | 1 |
| Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Cihlar, T; Ho, ES; Mulato, AS | 1 |
| Faller, B; Wohnsland, F | 1 |
| Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Bain, G; Beher, D; Chen, W; Jiang, X; Munoz, B; Peachey, J; Prasit, P; Shearman, MS; St-Jacques, R; Stock, N; Williamson, TL; Wrigley, JD | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Carrupt, PA; Martel, S; Ottaviani, G | 2 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Avdeef, A; Tam, KY | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Horie, T; Horiguchi, A; Kitamura, S; Kotake, Y; Ohshita, H; Ohta, S; Sanoh, S; Sugihara, K; Tateno, C; Tayama, Y | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Kourounakis, AP; Matralis, AN | 1 |
| Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P | 1 |
| Bujacz, A; Sekula, B | 1 |
| Gavalas, A; Kourti, M; Rekka, EA; Theodosis-Nobelos, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Darvesh, AS; Geldenhuys, WJ; Leeper, TC; Morris, DL; Sullivan, PG; Yonutas, HM | 1 |
| Anastácio Furtado Pacheco, P; Arruda, JC; Bello, ML; Castro, HC; da Silva, FC; Dantas, LP; de Freitas, HR; de Melo Reis, RA; Faria, RX; Ferreira, LBG; Ferreira, VF; Gonzaga, DTG; Moreira Maramaldo Costa, TE; Penido, C; Rodrigues, CR; Sposito Simões, AP; von Ranke, NL | 1 |
| Akgul, O; Alfawaz Altamimi, AS; Angeli, A; Bartolucci, G; Carta, F; Di Cesare Mannelli, L; Ghelardini, C; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| DeRose, EF; Duff, MR; Gabel, SA; Howell, EE; Krahn, JM; London, RE; Pedersen, LC | 1 |
| Uthgenannt, H | 1 |
| Cerutti, S; Forlani, A; Sperandeo, F | 1 |
| Siraux, P | 1 |
| Lehtola, J; Sipponen, P | 1 |
| Kajander, A; Martio, J | 1 |
| Car, A; Jajić, I; Krampac, I; Vitaus, M; Zenić, N; Zivković, M | 1 |
| Valtonen, EJ | 1 |
| Burdeĭnyĭ, AP | 1 |
| Pemberton, RE; Strand, LJ | 1 |
| Eidsaunet, W; Larsen, S; Osnes, M; Thom, E | 1 |
| Chaudri, HA; Ciccolunghi, SN; Schubiger, BI | 1 |
| Bach, GL | 1 |
| Czerniawska-Mysik, G; Gryglewski, RJ; Pieton, R; Szczeklik, A | 1 |
| Ciccolunghi, SN; Reddrop, R; Schubiger, BI | 1 |
| Mörsdorf, K; Wolf, G | 1 |
| Anggärd, E; Lundén, I; Oliw, E | 1 |
| Placheta, P; Siegmeth, W | 1 |
| Ahlberg, KF | 1 |
| Abdel-Halim, MS; Anggård, E; Sjöquist, B | 1 |
| Bendele, AM; Benslay, DN; Hom, JT; Lee, SJ; Lindstrom, TD; Naismith, RW; Ruterbories, KJ; Spaethe, SM | 1 |
| Beró, T; Jávor, T; Nagy, L; Vincze, A | 1 |
| Huskisson, EC; Scott, DL | 1 |
| Huskisson, EC | 2 |
| Blagbrough, IS; Daykin, MM; Doherty, M; Pattrick, M; Shaw, PN | 1 |
| de Pouvourville, G | 1 |
| Pradalier, A; Vincent, D | 1 |
| Dean, AD; Derby, LE; García Rodríguez, LA; Jick, H; Jick, SS | 1 |
| Mizraji, M | 1 |
| Carrasco, E; Felipe, A; Grau, M; Guasch, J; Juliá, S; Montero, JL | 2 |
| VanArsdel, PP | 1 |
| Calin, A; Elswood, J | 1 |
| Gribnau, F; van 't Hof, M; van de Putte, L; van Riel, P; Wijnands, M | 1 |
| Pena, M | 1 |
| Bacojanis, C; Beldecos, D; Karabelis, A; Karvounis, N; Kosmidis, P; Milonacis, N; Tsavaris, N; Zinelis, A | 1 |
| Waterworth, RF; Waterworth, SM | 1 |
| Corli, O; De Conno, F; Gallucci, M; Gottlieb, A; Speranza, R; Tamburini, M; Toscani, F; Ventafridda, V | 1 |
| Montenegro, MA; Palomino, H | 1 |
| Platt, PN | 1 |
| Briancon, D | 1 |
| Karbowski, A | 1 |
| Biasi, G; Cataldi, V; Fioravanti, A; Giordano, N; Marcolongo, R; Vaccai, D | 1 |
| Collet, P; Gravagna, B; Later, D; Lejeune, E; Llorca, G | 1 |
| Anderson, JJ; Firschein, HE; Meenan, RF | 1 |
| Paulus, HE; Schlegel, SI | 1 |
| Kolodny, AL | 1 |
| Kothari, HV; Ku, EC; Lee, W; Scholer, DW | 1 |
| Sallmann, AR | 2 |
| Johansson, J; Lahti, A | 1 |
| Zuckner, J | 1 |
| Altman, R | 1 |
| Ward, JR | 1 |
| Catalano, MA | 1 |
| Isomäki, H; Laitinen, O; Nissilä, M; Nuotio, P; Nykänen, E; Seppälä, E; Vapaatalo, H | 1 |
| Bernardi, F; Bolognesi, P; Frezza, R | 1 |
| Wilson, JT | 1 |
| Vetter, G | 1 |
| Bassi, GP; Borghi, C; Camarri, E; Cocco, F; Francucci, BM; Giannini, R; Giordano, N; Marcolongo, R; Mordini, M; Neri, D | 1 |
| Kimble, EF; Kothari, HV; Ku, EC; Lee, W; Liauw, L; Tjan, J | 1 |
| Kimble, EF; Kothari, H; Ku, EC; Lee, W; Liauw, LH | 1 |
| Macauley, D | 1 |
| Caldwell, JR | 1 |
| Machtey, I | 1 |
| Carlsson, I; Wennmalm, A | 1 |
| Cronberg, S; Söderberg, I; Wallmark, E | 1 |
| Isomäki, H; Kaarela, K; Kajander, A; Koota, K; Lehtinen, K; Luukkainen, R; Martio, J; Martio, T; Nissilä, M; Nuotio, P | 1 |
| Obel, AO | 1 |
| Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM | 1 |
| Bunchuk, NV; Murav'ev, IuV; Sigidin, IaA; Tsvetkova, ES | 1 |
| Sigidin, IaA; Tsvetkova, ES | 2 |
| Caruso, I; Cornelli, U; De Candia, O; Frizziero, L; Loizzi, P; Mattara, L; Riente, L; Trombetta, N | 1 |
| Stambuk, B; Zenić, N | 1 |
| Lorber, M; Nahir, M; Schapira, D; Scharf, Y | 1 |
| Pathy, MS | 1 |
| Dieppe, PA; Huskisson, EC; Jones, H; Scott, J | 1 |
| Kanková, D; Pavelka, K; Vojtísĕk, O | 1 |
| Anggård, E; Davila, D; Davila, T; Oliw, E | 1 |
| Friedman, DI; Schwarz, JS; Weisspapir, M | 1 |
| Bjarnason, I; Hayllar, J | 1 |
| Aleotti, A; Alvisi, V; Caselli, M; DeCarlo, L; LaCorte, R; Ruina, M; Trevisani, L; Trotta, F | 1 |
| Kajiyama, G; Lane, NE; Smith, RL | 1 |
| Geis, GS | 1 |
| Chemtob, S; Hanna, N; Lachapelle, P; Orquin, J; Roy, MS; Varma, DR | 1 |
| Dainaka, J; Hashii, H; Inoue, K; Kimura, K; Motonaga, A; Nishimura, T; Ueda, F; Yamate, K | 1 |
| Bortnichak, EA; Lanza, L; Walker, AM; Yood, RA | 1 |
| Ardia, A; Baggio, A; Cornelli, U; Franchini, S | 1 |
| Backman, EA; Beckman, EA; Kulling, PE; Skagius, AS | 1 |
| Butrón, F; Galicia, A; Martinez-Zurita, F; Zamora, G | 1 |
| Clarke, GD; MacPherson, IS; Petrone, G; Spangler, RS | 1 |
| Bacon, P | 1 |
| Giraud, AS; Skeljo, MV; Yeomans, ND | 1 |
| Bruyn, GA; Geis, GS; Melo Gomes, JA; Roth, SH; Woods, EM; Zeeh, J | 1 |
| DeLapp, RE; Eversmeyer, W; Jensen, CP; Poland, M | 1 |
| DeLapp, RE; Morgan, GJ; Poland, M | 1 |
| DeLapp, RE; Lister, BJ; Poland, M | 1 |
| Alfredsson, L; Kaufman, DW; Kelly, JP; Koff, RS; Laszlo, A; Shapiro, S; Sheehan, JE; Wiholm, BE | 1 |
| Dingle, JT; Leeming, MR; Martindale, JJ | 1 |
| Cahill, RJ; Gilvarry, J; O'Morain, CA; Sant, SM | 1 |
| Carrabba, M; Galante, A; Manfredi, B; Panerai, AE; Pisati, R; Sacerdote, P | 1 |
| Carryl, OR; Spangler, RS | 1 |
| Carson, JL; Manoukian, AV | 1 |
| Becker, L; Eberlein-König, B; Przybilla, B | 1 |
| Ardizzone, S; Bianchi Porro, G; Brunetti, G; Frizziero, L; Grandinetti, G; Menegatti, M; Miglioli, M; Montrone, F; Petrillo, M; Vaira, D | 1 |
| Bowdler, J; Frerick, H; Kornasoff, D; Montull, E | 1 |
| Agut, J; Conejo, L; Márquez, M; Ortiz, JA; Palop, D; Sacristán, A | 1 |
| Caruso, FS; Frenk, H; Lu, J; Mao, J; Mayer, DJ; Price, DD | 1 |
| Flores-Murrieta, FJ; Granados-Soto, V; Pérez-Urizar, J; Robles, MB; Torres-López, JE | 1 |
| Borgå, B; Borgå, O | 1 |
| Campbell, F; Lipscomb, GR; Rees, WD | 1 |
| Colombo, G; Giombini, A; Pamich, T; Peruzzi, E; Pisati, R | 1 |
| Brusis, T; Metternich, FU; Parandeh-Shab, F | 1 |
| Casini, ML; Mattei, E; Panzironi, C; Saso, L; Silvestrini, B; Valentini, G | 1 |
| McKenna, F | 1 |
| Andersson, T; Bredberg, E; Lagerström, PO; Naesdal, J; Wilson, I | 1 |
| Christophidis, N; Kwiatek, R; Scharf, S; Ugoni, A | 1 |
| Barra, J; Bustamante, P; Peña, MA | 1 |
| Duque-Oliart, A; García-Rodríguez, LA; Pérez-Gutthann, S; Varas-Lorenzo, C | 1 |
| Iley, J; Mendes, E; Moreira, R; Souza, S | 1 |
| Biczó, A; Huszár, L; Szabó, G; Temesvári, A; Tóthfalusi, L; Ujpál, M | 1 |
| Cullen , DJ; Doherty, M; Garner, S; Garrud, P; Hawkey, CJ; Holmes, S; Logan, RF; Maynard, A; Seager, JM; Wilson, JV | 1 |
| Cullen, DJ; Doherty, M; Garner, S; Garrud, P; Hawkey, CJ; Holmes, S; Logan, RF; Maynard, A; Pearson, G; Seager, JM; Wilson, JV | 1 |
| Callahan, LF; Cummins, P; Pincus, T; Swearingen, C | 1 |
| Brune, K; Lemmer, B | 1 |
| Jick, SS | 1 |
| Bouldin, MB; Clowers-Webb, HE; Davis, JL; Davis, MD; McEvoy, MT | 1 |
| Arnout, J; Buntinx, A; Dallob, A; De Lepeleire, I; De Schepper, PJ; Depré, M; Ebel, DL; Gertz, BJ; Schwartz, JI; Tanaka, W; Van Hecken, A; Wong, PH; Wynants, K | 1 |
| Tive, L | 1 |
| Clements, S; Cox, M; Harrall, RL; Hazleman, BL; Riley, GP | 1 |
| Bujak-Gizycka, B; Kłys, M; Latacz, B; Skupień, E | 1 |
| Barbuzzi, T; Bonina, FP; de Caprariis, P; Palagiano, F; Puglia, C; Rimoli, MG; Saija, A | 1 |
| Browning, RA; Burgess, FW | 1 |
| Deray, G | 1 |
| Cassoux, N; Darondeau, J; LeHoang, P; Milazzo, G; Papa, V; Santiago, PY; Santocono, M; Servolle, V; Sourdille, P | 1 |
| Lozano, JJ; Pouplana, R; Ruiz, J | 1 |
| Bozdag, S; Caliş, S; Hincal, AA; Kaş, HS; Tunçay, M | 1 |
| Di Bella, A; Milazzo, G; Papa, V; Russo, P; Russo, S; Santocono, M | 1 |
| Downing, SJ; Leese, HJ; Maguiness, SD; Tay, JI; Watson, A | 1 |
| Kent, JD; Leese, PT; Recker, DP; Talwalker, S | 1 |
| Bonina, F; Puglia, C; Saija, A; Santagati, NA; Tita, B; Tomaino, A | 1 |
| Sadowski, T; Steinmeyer, J | 1 |
| Khan, AI; Lei, L; Norquist, AJ; O'Hare, D | 1 |
| Kato, S; Kunikata, T; Miyazawa, T; Takeuchi, K; Tanaka, A | 1 |
| Cmiel, A; Mejza, F; Szczeklik, A; Tuleja, E | 1 |
| Branson, J; Ford, M; Kellett, N; Mair, S; Milosavljev, S; Rordorf, C; Scott, G | 1 |
| Harley, C; Wagner, S | 1 |
| Burian, M; Geisslinger, G | 1 |
| Chen, BY; Cheng, NN; Li, D; Shi, W; Wang, YM | 1 |
| Brouwers, JR; de Jong-van den Berg, LT; de Vries-Bots, AM; Piersma-Wichers, M; Plat, AW; Slomp, J; van Dijk, AA; van Dijk, KN | 1 |
| Aguilar, C; Borrull, F; Calull, M; Macià, A | 1 |
| Davies, C; DeVoss, JJ; Gillam, EM; Graham, SE; Pearson, A; Scott, JR; Witham, K | 1 |
| Ashworth, NL; Muhajarine, N; Peloso, PM; Stang, M | 2 |
| García Rodríguez, LA; González-Pérez, A; Maguire, A; Varas-Lorenzo, C | 1 |
| Ehrsam, E; Farkouh, M; Gitton, X; Hawkey, CJ; Huels, J; Richardson, P | 1 |
| Lanes, S; Singh, G; Triadafilopoulos, G | 1 |
| Antépara, I; Caballero, MR; de Weck, AL; Esparza, R; Gamboa, P; Sanz, ML; Urrutia, I | 1 |
| Summerton, N | 1 |
| Dahlborg, R; Day, CA; Jacob, RF; Mason, RP; Walter, MF; Weng, Y | 1 |
| Morillo, LE | 2 |
| Kamimura, H; Mano, Y; Usui, T | 1 |
| Alten, R; Geusens, P; Kralidis, G; Krammer, G; Richardson, P; Rovensky, J; Sloan, VS | 1 |
| Dial, EJ; Dohrman, AJ; Lichtenberger, LM; Romero, JJ | 1 |
| Foster, GD; Thomas, PM | 1 |
| Berlin, JA; Chittams, J; Jaskowiak, J; Kimmel, SE; Kishel, L; Reilly, M; Strom, BL | 1 |
| Lucas, R; Mitchell, JA; Vojnovic, I; Warner, TD | 1 |
| Goldstein, JL; Mayne, TJ; Rabeneck, L; Rublee, DA; Vu, A | 1 |
| Ferrer, I; Thurman, EM | 1 |
| Kronberg, L; Lindqvist, N; Tuhkanen, T | 1 |
| Quintana, JB; Reemtsma, T; Weiss, S | 1 |
| McGinnity, DF; Riley, RJ; Trigg, S; Tucker, J | 1 |
| Choi, JS; Han, HK; Jin, MJ | 1 |
| McCarthy, DM | 1 |
| Bierma-Zeinstra, SM; Hazes, JM; Koes, BW; Pols, HA; Reijman, M; Stricker, BH | 1 |
| Han, HK; Oh, YH | 1 |
| Chan, VW; Clark, AJ; Davis, JC; Jayawardene, S; Kellstein, D; Wolf, RS | 1 |
| Bishop-Bailey, D; Mitchell, JA; Vojnovic, I; Warner, TD | 1 |
| Nachajski, MJ; Zgoda, MM | 1 |
| Bjarnason, I; Bjornsson, E; Maiden, L; Premchand, P; Sherwood, R; Smale, S; Takeuchi, K; Thjodleifsson, B | 1 |
| Agrawal, NM; Andrade-Ortega, L; Bello, AE; Eisen, GM; Fort, JG; Goldstein, JL; Hanrahan, PS; Levy, RA; Singh, G; Stenson, WF; Triadafilopoulos, G; Wallemark, C | 1 |
| Baraliakos, X; Bohl-Bühler, MH; Braun, J; Feldtkeller, E; Zochling, J | 1 |
| Kandefer-Szerszeń, M; Majdan, M; Parada-Turska, J; Rzeski, W; Turski, WA | 1 |
| García Rodríguez, LA; Hernández-Díaz, S; Varas-Lorenzo, C | 1 |
| Fortea, J; Lamarca, R; Letzel, H; Mégard, Y; Raber, A | 1 |
| Castellsague, J; Maguire, A; Perez-Gutthann, S; Varas-Lorenzo, C | 1 |
| Takahira, Y; Takeuchi, K; Tanaka, A; Yokota, A | 1 |
| Henry, D; McGettigan, P | 2 |
| Baba, A; Yoshioka, T | 1 |
| Brookhart, MA; Rassen, J; Schneeweiss, S; Solomon, DH; Wang, PS | 1 |
| Deray, G; Montalescot, G; Sibilia, J | 1 |
| Berger, MY; Damen, L; Koes, BW; Merlijn, V; Passchier, J; Verhagen, AP | 1 |
| Lee, PI; Zahedi, P | 1 |
| Lukosek, M; Nachajski, MJ; Zgoda, MM | 1 |
| Einecke, D | 1 |
| Abramson, SB; Chesebro, JH; Farkouh, ME; Fuster, V; Greenberg, JD; Hochman, JS; Jeger, RV; Kirshner, H; Lay, CL; Matchaba, PT; Mellein, B; Ramanathan, K; Ruland, S; Verheugt, FW | 1 |
| Ashcroft, DM; Chen, LC | 1 |
| Jacobs, P; Loyd, M; Rublee, D | 1 |
| Gitton, X; Hawkey, CJ; Krammer, G; Matchaba, P; Mellein, B; Richard, D; Sallstig, P; Smalley, W; Stricker, K; Weinstein, WM | 1 |
| Andriulli, A; Colaizzo, D; Dallapiccola, B; Di Mario, F; Franceschi, M; Grandone, E; Leandro, G; Niro, V; Pilotto, A; Scarcelli, C; Seripa, D | 1 |
| Esplugas, S; Giménez, J; Méndez-Arriaga, F | 1 |
| Hawkey, CJ; Krammer, G; Murphy, V; Rebuli, R; Richard, D; Stricker, K; Weinstein, WM | 1 |
| Albert, J; Arulmani, U; Bolten, W; Ell, C; Fortun, P; Hawkey, CJ; Hugot, JL; Keuchel, M; Krammer, G; McAlindon, M; Rebuli, R; Schumann, S; Shonde, A; Simon, B; Toth, E; Yu, V | 1 |
| Borzak, S; Hennekens, CH | 1 |
| El Masry, MA; Gamie, Z; Macfarlane, RJ; Ng, BH; Schizas, C; Tsiridis, E; Velonis, S | 1 |
| Barton, S; Daniels, S; Gitton, X; Stricker, K; Zhou, W | 1 |
| Molnár-Perl, I; Palkó, G; Sebok, A; Vasanits-Zsigrai, A; Záray, G | 1 |
| Leufkens, HG; Rietbrock, S; Setakis, E; van Staa, TP | 1 |
| Chesebro, JH; Farkouh, ME; Gitton, X; Jeger, R; Kirshner, H; Krammer, G; Matchaba, P; Mellein, B; Ruland, S; Sallstig, P; Stricker, K; Verheugt, FW | 1 |
| Nogueira, JM; Portugal, FC; Silva, AR | 1 |
| Asami, M; Fujiwara, J; Kunikane, S; Manabe, S; Matsuda, M; Simazaki, D | 1 |
| Adekunle, F; Andrews, C; Ellis, G; Kinch, H; Kyle, C; Zachariah, J | 1 |
| Galliard-Grigioni, KS; Reinhart, WH | 1 |
| Brandenburg, K; Garidel, P; Howe, J; Manrique-Moreno, M; Moreno, MM; Suwalsky, M | 1 |
| Obach, RS | 1 |
| Li, L | 1 |
| López-Mahía, P; Muniategui-Lorenzo, S; Prada-Rodríguez, D; Quintana, JB; Rodil, R | 1 |
| Chang, AC; Wu, L; Xu, J | 1 |
| Aberer, W; Blanca, M; Correia, S; De Weck, AL; Erdman, S; Gamboa, PM; Jermann, JM; Kanny, G; Kowalski, M; Mayorga, L; Medrala, W; Merk, A; Sainte-Laudy, J; Sanz, ML; Schneider, MS; Sczczeklik, A; Sturm, GJ; Weber, JM; Wedi, A | 1 |
| Arbogast, PG; Castellsague, J; Chung, CP; Daugherty, JR; García-Rodríguez, LA; Murray, KT; Ray, WA; Stein, CM; Varas-Lorenzo, C | 1 |
| Choy, EH; Gaugris, S; Jansen, JP; Nash, JT; Ostor, A; Stam, W | 1 |
| Barcelo, D; Budzinski, H; Castiglioni, S; de Alencastro, LF; Farre, M; Gans, O; Heath, E; Kosjek, T; Langford, K; Loos, R; Petrovic, M; Quintana, JB; Radjenović, J; Rocca, LM; Tsipi, D | 1 |
| Helenkár, A; Molnár-Perl, I; Sebok, A; Vasanits-Zsigrai, A; Záray, G | 1 |
| Aguilar, C; Borrull, F; Botello, I; Calull, M | 1 |
| Ezoddin, M; Hidalgo, M; Jönsson, JA; Larsson, E; Sagristà, E; Salvadó, V | 1 |
| Avila, C; Bayona, JM; García, J; Matamoros, V; Pedescoll, A | 1 |
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42 review(s) available for diclofenac and naproxen
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Drug therapy of ankylosing spondyloarthritis (Bechterew's disease)].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Apazone; Butadienes; Cyclophosphamide; Diclofenac; Drug Combinations; Drug Evaluation; Glycolates; Gold; Humans; Ibuprofen; Indomethacin; Ketoprofen; Levamisole; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates; Spondylitis, Ankylosing; Sulindac | 1978 |
[Migraine and non-steroidal anti-inflammatory agents].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic Acid; Flurbiprofen; Humans; Metoclopramide; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Randomized Controlled Trials as Topic | 1992 |
Etodolac: analgesic effects in musculoskeletal and postoperative pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Aspirin; Athletic Injuries; Back Pain; Bursitis; Diclofenac; Dose-Response Relationship, Drug; Etodolac; Humans; Indoleacetic Acids; Musculoskeletal System; Naproxen; Pain, Postoperative; Piroxicam; Tendinopathy | 1990 |
A global safety evaluation of etodolac.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Etodolac; Female; Humans; Indoleacetic Acids; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam | 1989 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diclofenac; Drug Hypersensitivity; Gastrointestinal Diseases; Hematologic Diseases; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Diseases; Kinetics; Naproxen; Phenylbutazone; Piroxicam; Salicylates; Thiazines | 1986 |
Clinical pharmacology of pediatric antipyretic drugs.
Topics: Acetaminophen; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Choline; Diclofenac; Drug Combinations; Humans; Ibuprofen; Kinetics; Naproxen; Salicylates | 1985 |
Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Diclofenac; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Phenylbutyrates; Piroxicam; Propionates; Sulindac; Thiazines | 1982 |
Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin.
Topics: Adult; Animals; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Female; Gastric Mucosa; Gout; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Phenylacetates; Platelet Aggregation; Rheumatic Diseases; Spondylitis, Ankylosing; Ulcer | 1980 |
Nonsteroidal anti-inflammatory drug-induced hepatic disorders. Incidence and prevention.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chemical and Drug Induced Liver Injury; Cohort Studies; Diclofenac; Humans; Incidence; Indomethacin; Liver; Liver Diseases; Naproxen; Oxaprozin; Phenylbutazone; Propionates; Risk Factors; Sulindac | 1996 |
Naproxen-associated linear IgA bullous dermatosis: case report and review.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Diclofenac; Humans; Immunoglobulin A; Male; Naproxen; Piroxicam; Prednisone; Skin Diseases, Vesiculobullous | 2000 |
Celecoxib clinical profile.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; In Vitro Techniques; Isoenzymes; Kidney Diseases; Membrane Proteins; Middle Aged; Naproxen; Osteoarthritis; Pain; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Treatment Outcome | 2000 |
Nimesulide, a balanced drug for the treatment of osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diclofenac; Etodolac; Humans; Naproxen; Osteoarthritis; Stomach Diseases; Sulfonamides; Treatment Outcome | 2001 |
[Clinical pharmacology of the selective COX-2 inhibitors].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Clinical Trials, Phase III as Topic; Cyclooxygenase Inhibitors; Diclofenac; Humans; Isoxazoles; Lactones; Naproxen; Osteoarthritis; Pain; Pain, Postoperative; Placebos; Pyrazoles; Sulfonamides; Sulfones | 2003 |
[Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; China; Diclofenac; Humans; Ibuprofen; Meloxicam; Nabumetone; Naproxen; Osteoarthritis; Oxaprozin; Propionates; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiazoles | 2003 |
Migraine headache.
Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Diclofenac; Drug Therapy, Combination; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2003 |
Migraine headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Sumatriptan; Triazoles; Tryptamines | 2004 |
Ulcers, Helicobacter pylori infection, platelets and gastrointestinal complications of non-steroidal anti-inflammatory drugs: what are the connections?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclooxygenase Inhibitors; Diclofenac; Gastrointestinal Hemorrhage; Helicobacter Infections; Humans; Ibuprofen; Lactones; Naproxen; Peptic Ulcer; Risk Factors; Sulfones | 2002 |
Non-steroidal antiinflammatory drugs and the risk of acute myocardial infarction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cohort Studies; Diclofenac; Dose-Response Relationship, Drug; Humans; Ibuprofen; Lactones; Myocardial Infarction; Naproxen; Risk Factors; Sulfones | 2006 |
Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Lactones; Naproxen; Pyrazoles; Risk; Sulfonamides; Sulfones | 2006 |
[What do we know about the cardiovascular toxicity of the NSAIDs?].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Case-Control Studies; Celecoxib; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Follow-Up Studies; Humans; Isoxazoles; Lactones; Meta-Analysis as Topic; Middle Aged; Naproxen; Pyrazoles; Randomized Controlled Trials as Topic; Risk Factors; Sulfonamides; Sulfones; Thrombosis; Time Factors | 2006 |
Is any one analgesic superior for episodic tension-type headache?
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Ibuprofen; Ketoprofen; Naproxen; Nonprescription Drugs; Secondary Prevention; Tension-Type Headache; Treatment Outcome | 2006 |
Risk of myocardial infarction associated with selective COX-2 inhibitors: meta-analysis of randomised controlled trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib; Humans; Isoxazoles; Lactones; Models, Statistical; Myocardial Infarction; Naproxen; Odds Ratio; Pyrazoles; Pyridines; Randomized Controlled Trials as Topic; Risk; Risk Factors; Sulfonamides; Sulfones | 2007 |
Pharmacological treatment of heterotopic ossification following hip and acetabular surgery.
Topics: Acetabulum; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Celecoxib; Diclofenac; Humans; Indomethacin; Naproxen; Ossification, Heterotopic; Postoperative Complications; Pyrazoles; Sulfonamides | 2008 |
Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Diclofenac; Humans; Ibuprofen; Naproxen | 2011 |
Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Vessels; Coronary Disease; Cyclooxygenase 2 Inhibitors; Diclofenac; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Ibuprofen; Myocardial Infarction; Naproxen; Stroke; Vascular Diseases | 2013 |
Vascular effects of nonsteroidal antiinflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Diclofenac; Humans; Naproxen; Primary Prevention; Risk Factors; Secondary Prevention | 2013 |
Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: a systematic review and network meta-analysis.
Topics: Acetaminophen; Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Hyaluronic Acid; Ibuprofen; Injections, Intra-Articular; Naproxen; Osteoarthritis, Knee; Pain; Pyrazoles; Sulfonamides; Treatment Outcome; Viscosupplements | 2015 |
[Cardiovascular side effects of non-steroidal anti-inflammatory drugs in the light of recent recommendations. Diclofenac is not more dangerous].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cardiovascular System; Diclofenac; Drug Interactions; Humans; Ibuprofen; Naproxen | 2015 |
Ibuprofen for acute treatment of episodic tension-type headache in adults.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Ketoprofen; Naproxen; Numbers Needed To Treat; Pain Measurement; Piroxicam; Randomized Controlled Trials as Topic; Tension-Type Headache; Time Factors | 2015 |
Nonaspirin Nonsteroidal Anti-Inflammatory Drugs and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Observational Studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cerebral Hemorrhage; Diclofenac; Humans; Ibuprofen; Incidence; Indomethacin; Lactones; Meloxicam; Naproxen; Observational Studies as Topic; Odds Ratio; Piroxicam; Proportional Hazards Models; Stroke; Sulfones; Thiazines; Thiazoles | 2016 |
Celecoxib for osteoarthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Diclofenac; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Measurement; Placebos; Quality of Life; Randomized Controlled Trials as Topic | 2017 |
Gastrointestinal safety of etoricoxib in osteoarthritis and rheumatoid arthritis: A meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Humans; Naproxen; Osteoarthritis; Pyridines; Randomized Controlled Trials as Topic; Sulfones | 2018 |
Efficacy and safety of over-the-counter analgesics for primary dysmenorrhea: A network meta-analysis.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Dysmenorrhea; Female; Humans; Ibuprofen; Ketoprofen; Middle Aged; Naproxen; Network Meta-Analysis; Nonprescription Drugs; Treatment Outcome; Young Adult | 2020 |
Toxicity of the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) acetylsalicylic acid, paracetamol, diclofenac, ibuprofen and naproxen towards freshwater invertebrates: A review.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ecosystem; Fresh Water; Humans; Ibuprofen; Invertebrates; Naproxen | 2020 |
Metabolism of non-steroidal anti-inflammatory drugs by non-target wild-living organisms.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Naproxen; Pharmaceutical Preparations | 2021 |
Pharmaceuticals as emerging pollutants: Case naproxen an overview.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Environmental Pollutants; Ibuprofen; Naproxen; Pharmaceutical Preparations; Water Pollutants, Chemical | 2022 |
Lessons from 20 years with COX-2 inhibitors: Importance of dose-response considerations and fair play in comparative trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Fibrinolytic Agents; Humans; Ibuprofen; Lactones; Naproxen; Prostaglandins; Prostaglandins I; Sulfones; Thromboxanes | 2022 |
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Child; Chronic Disease; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Infant; Ketoprofen; Ketorolac; Meloxicam; Naproxen; Niflumic Acid; Pain | 2022 |
Literature Review: Evaluation of Drug Removal Techniques in Municipal and Hospital Wastewater.
Topics: Anti-Bacterial Agents; Carbamazepine; Diclofenac; Hospitals; Naproxen; Norfloxacin; Ofloxacin; Ozone; Pharmaceutical Preparations; Sewage; Sulfamethoxazole; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2022 |
Occurrence, toxicity, impact and removal of selected non-steroidal anti-inflammatory drugs (NSAIDs): A review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Naproxen; Wastewater; Water; Water Pollutants, Chemical | 2023 |
86 trial(s) available for diclofenac and naproxen
| Article | Year |
|---|---|
[Gastrointestinal discharge of blood due to the administration of feprazon, naproxen, diclofenac].
Topics: Diclofenac; Feprazone; Gastrointestinal Hemorrhage; Humans; Melena; Naphthaleneacetic Acids; Naproxen; Phenylacetates; Phenylbutazone | 1977 |
Diclofenac (Voltaren) for the treatment of osteo-arthrosis: a double-blind comparison with naproxen.
Topics: Aged; Clinical Trials as Topic; Diclofenac; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Naphthaleneacetic Acids; Naproxen; Osteoarthritis; Phenylacetates | 1977 |
A gastroscopic and histological double-blind study of the effects of diclofenac sodium and naproxen on the human gastric mucosa.
Topics: Adult; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Female; Gastric Juice; Gastric Mucosa; Gastroscopy; Humans; Male; Naphthaleneacetic Acids; Naproxen; Phenylacetates; Radiography | 1977 |
Diclofenac sodium (Voltaren) and naproxen in the treatment of rheumatoid arthritis: a comparative double-blind study.
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Naproxen; Phenylacetates | 1978 |
A double-blind multicentre comparison of diclofenac sodium and naproxen in osteoarthrosis of the hip.
Topics: Adult; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Female; Hip Joint; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Phenylacetates | 1978 |
A comparative short-term trial with Voltaren (diclofenac sodium) and naproxen in soft-tissue rheumatism.
Topics: Adult; Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Naproxen; Phenylacetates; Rheumatic Diseases; Time Factors | 1978 |
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin | 1979 |
Effect of diclofenac and naproxen on gastroduodenal mucosa.
Topics: Adult; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Duodenum; Female; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Humans; Intestinal Mucosa; Male; Naproxen; Phenylacetates; Placebos | 1979 |
The value and results of long-term studies with diclofenac sodium (Voltarol).
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Tolerance; Hematologic Tests; Humans; Indomethacin; Liver Function Tests; Naproxen; Phenylacetates; Time Factors | 1979 |
Comparative clinical trials with diclofenac sodium (Voltarol) and naproxen in rheumatic conditions: investigation of possible changes in diclofenac dose and dose interval.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Drug Tolerance; Female; Humans; Male; Middle Aged; Naproxen; Phenylacetates; Time Factors | 1979 |
[Long-term comparative study: diclofenac (voltaren) and naproxen (proxen) in arthritis].
Topics: Arthritis; Diclofenac; Drug Evaluation; Hip Joint; Humans; Knee Joint; Naproxen; Phenylacetates | 1978 |
A clinical comparison of two leading non-steroidal anti-inflammatory drugs.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cross-Over Studies; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen | 1991 |
Four commonly prescribed non-steroidal anti-inflammatory drugs for rheumatoid arthritis.
Topics: Administration, Oral; Arthritis, Rheumatoid; Cross-Over Studies; Delayed-Action Preparations; Diclofenac; Humans; Indomethacin; Naproxen; Pain; Piroxicam; Single-Blind Method; Surveys and Questionnaires | 1991 |
[Migraine and non-steroidal anti-inflammatory agents].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic Acid; Flurbiprofen; Humans; Metoclopramide; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Randomized Controlled Trials as Topic | 1992 |
Clinical response to etodolac in the management of pain.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Athletic Injuries; Bursitis; Diclofenac; Etodolac; Female; Gout; Humans; Indoleacetic Acids; Male; Naproxen; Pain, Postoperative; Palliative Care; Tendinopathy | 1990 |
Longterm treatment with nonsteroidal antiinflammatory drugs in rheumatoid arthritis: a prospective drug survival study.
Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Dose-Response Relationship, Drug; Female; Humans; Indomethacin; Male; Middle Aged; Naproxen; Prospective Studies; Sex Factors; Time Factors | 1991 |
Etodolac: analgesic effects in musculoskeletal and postoperative pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Aspirin; Athletic Injuries; Back Pain; Bursitis; Diclofenac; Dose-Response Relationship, Drug; Etodolac; Humans; Indoleacetic Acids; Musculoskeletal System; Naproxen; Pain, Postoperative; Piroxicam; Tendinopathy | 1990 |
A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancer-induced fever.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Fever; Humans; Indomethacin; Male; Naproxen; Neoplasms; Paraneoplastic Syndromes | 1990 |
Sodium naproxen versus sodium diclofenac in cancer pain control.
Topics: Aged; Diclofenac; Female; Humans; Male; Naproxen; Neoplasms; Pain, Intractable; Random Allocation; Single-Blind Method | 1990 |
Recent clinical experience with etodolac in the treatment of osteoarthritis of the knee.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Etodolac; Female; Humans; Indoleacetic Acids; Knee Joint; Male; Middle Aged; Multicenter Studies as Topic; Naproxen; Osteoarthritis; Piroxicam; Random Allocation | 1989 |
International experience with etodolac therapy for rheumatoid arthritis: an interim report of comparative efficacy.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Etodolac; Female; Humans; Indoleacetic Acids; Male; Middle Aged; Multicenter Studies as Topic; Naproxen; Piroxicam; Prospective Studies; Random Allocation | 1989 |
A global safety evaluation of etodolac.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Etodolac; Female; Humans; Indoleacetic Acids; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam | 1989 |
Sensitivity of a health status measure to short-term clinical changes in arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Health Status Indicators; Health Surveys; Humans; Male; Middle Aged; Naproxen; Random Allocation; Sensitivity and Specificity | 1989 |
Two double blind trials of diclofenac sodium with aspirin and with naproxen in the treatment of patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Gastrointestinal Diseases; Humans; Middle Aged; Naproxen; Nervous System Diseases; Severity of Illness Index | 1988 |
International experience with diclofenac in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone | 1986 |
International experiences with diclofenac in osteoarthritis.
Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Naproxen; Osteoarthritis; Random Allocation; Sulindac | 1986 |
Efficacy of diclofenac in osteoarthritis. Experience in the United States.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Hip Joint; Humans; Knee Joint; Middle Aged; Naproxen; Osteoarthritis; Random Allocation; United States | 1986 |
Worldwide safety experience with diclofenac.
Topics: Adult; Aged; Aspirin; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Gastrointestinal Diseases; Gastroscopy; Humans; Ibuprofen; Kidney Diseases; Middle Aged; Naproxen; Occult Blood; Piroxicam; Thiazines | 1986 |
[Comparison of the action of 3 non-steroidal anti-inflammatory agents in the control of post-operative pain. Effectiveness of NSAID against pain].
Topics: Adult; Anti-Inflammatory Agents; Diclofenac; Female; Humans; Male; Middle Aged; Mouth; Naproxen; Pain, Postoperative; Piroxicam; Placebos; Surgical Flaps; Thiazines | 1985 |
A comparison of naproxen and diclofenac sodium in the treatment of osteoarthritis in elderly patients.
Topics: Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Humans; Male; Naproxen; Osteoarthritis; Phenylacetates | 1985 |
Double-blind preference and compliance multicentre study in osteoarthritis: once-a-day treatment.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Administration Schedule; Humans; Indomethacin; Indoprofen; Ketoprofen; Middle Aged; Naproxen; Osteoarthritis; Pain; Patient Compliance; Piroxicam; Thiazines | 1985 |
Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm.
Topics: Adolescent; Adult; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Female; Forearm; Humans; Hyperemia; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Regional Blood Flow; Thiazines | 1983 |
Comparison of the analgesic effect of ten nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Ketoprofen; Male; Middle Aged; Naproxen; ortho-Aminobenzoates; Quinazolines | 1984 |
[Current trends in pharmacotherapy of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Humans; Levamisole; Naproxen; Phenylacetates | 1980 |
[Comparative effectiveness of new antirheumatic drugs].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Flufenamic Acid; Humans; Indomethacin; Naproxen | 1980 |
[Comparative efficacy of voltaren and naproxen in rheumatoid arthritis (double-blind trial)].
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Naproxen; Phenylacetates | 1981 |
[Activity of diclofenac after a single, evening administration as compared with naproxen, in ambulatory patients with rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Female; Humans; Male; Middle Aged; Naproxen; Phenylacetates; Suppositories | 1981 |
[Comparative double-blind trial of diclophenac-sodium and naproxen in hip arthrosis].
Topics: Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Hip Joint; Humans; Middle Aged; Naproxen; Osteoarthritis; Phenylacetates | 1981 |
A comparative study of naproxen with diclofenac sodium in osteoarthrosis of the knees.
Topics: Adult; Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Phenylacetates | 1982 |
Efficacy and upper GI safety of diclofenac/misoprostol, piroxicam and naproxen in patients with osteoarthritis.
Topics: Diclofenac; Double-Blind Method; Drug Combinations; Female; Gastrointestinal Diseases; Humans; Male; Misoprostol; Naproxen; Osteoarthritis; Piroxicam; Safety | 1993 |
Comparative studies with tolfenamic acid in rheumatic disorders.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Naproxen; ortho-Aminobenzoates; Osteoarthritis; Pain | 1994 |
Single blind study to evaluate the efficacy and safety of naproxen gel compared with diclophenac emulgel in the treatment of soft tissue injuries.
Topics: Adult; Contusions; Diclofenac; Edema; Female; Gels; Humans; Male; Middle Aged; Naproxen; Pain Measurement; Single-Blind Method; Soft Tissue Injuries; Sprains and Strains | 1994 |
Worldwide experience with etodolac (Lodine) 300 mg b.i.d. in the treatment of osteoarthritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Diclofenac; Double-Blind Method; Etodolac; Global Health; Hip Joint; Humans; Indomethacin; Knee Joint; Middle Aged; Naproxen; Osteoarthritis; Pain; Piroxicam; Time Factors | 1993 |
Double-blind comparison of efficacy and gastroduodenal safety of diclofenac/misoprostol, piroxicam, and naproxen in the treatment of osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Diclofenac; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Misoprostol; Naproxen; Osteoarthritis; Peptic Ulcer; Piroxicam | 1993 |
Safety experience with nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Efficacy and safety of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in the elderly.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Male; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Efficacy of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Life Style; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Nonsteroidal anti-inflammatory drug use in relation to major upper gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Diclofenac; Female; Gastrointestinal Hemorrhage; Humans; Hungary; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Risk Factors; Sweden; United States | 1993 |
Plasma and synovial fluid interleukin-1, interleukin-6 and substance P concentrations in rheumatoid arthritis patients: effect of the nonsteroidal anti inflammatory drugs indomethacin, diclofenac and naproxen.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Female; Humans; Indomethacin; Interleukin-1; Interleukin-6; Male; Middle Aged; Naproxen; Substance P; Synovial Fluid | 1995 |
Prevention with sucralfate gel of NSAID-induced gastroduodenal damage in arthritic patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Duodenal Ulcer; Female; Gels; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Stomach Ulcer; Sucralfate | 1996 |
Aceclofenac is a well-tolerated alternative to naproxen in the treatment of osteoarthritis.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Diclofenac; Double-Blind Method; Drug Administration Schedule; Edema; Erythema; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Range of Motion, Articular; Treatment Outcome | 1997 |
Diclofenac dispersible provides superior analgesia with faster onset of action compared to naproxen granular in patients with acute, painful, minor sports injuries.
Topics: Acute Disease; Adolescent; Adult; Aged; Ambulatory Care; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Athletic Injuries; Diclofenac; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Movement; Naproxen; Pain; Pain Measurement; Pressure; Safety; Skin Temperature; Time Factors | 1997 |
[Pain therapy after tonsillectomy in adults].
Topics: Adult; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naproxen; Pain Measurement; Pain Threshold; Pain, Postoperative; Tonsillectomy; Tramadol | 1998 |
Diclofenac/misoprostol: the European clinical experience.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Drug Combinations; Duodenal Ulcer; Duodenoscopy; Gastroscopy; Humans; Misoprostol; Naproxen; Osteoarthritis; Piroxicam; Stomach Ulcer | 1998 |
Lack of drug-drug interaction between three different non-steroidal anti-inflammatory drugs and omeprazole.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cross-Over Studies; Diclofenac; Drug Interactions; Female; Humans; Male; Naproxen; Omeprazole; Piroxicam | 1998 |
NSAIDs and faecal blood loss in elderly patients with osteoarthritis: is plasma half-life relevant?
Topics: Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diclofenac; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Half-Life; Humans; Male; Middle Aged; Naproxen; Occult Blood; Osteoarthritis; Piroxicam | 1998 |
[Comparative study of the analgesic effect of Apranax and Cataflam after oral surgical procedures].
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Male; Maxillofacial Injuries; Middle Aged; Naproxen; Oral Surgical Procedures; Pain, Postoperative | 1999 |
Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers.
Topics: Adolescent; Adult; Bleeding Time; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Lipopolysaccharides; Meloxicam; Membrane Proteins; Middle Aged; Naproxen; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfones; Thiazines; Thiazoles; Thromboxane B2 | 2000 |
Naproxen ophthalmic solution to manage inflammation after phacoemulsification.
Topics: Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Female; Humans; Lens Implantation, Intraocular; Male; Naproxen; Ophthalmic Solutions; Pain, Postoperative; Phacoemulsification; Prospective Studies; Safety; Uveitis, Anterior | 2002 |
Topical naproxen sodium for inhibition of miosis during cataract surgery. Prospective, randomized clinical trials.
Topics: Administration, Topical; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Cataract Extraction; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Phacoemulsification; Pupil | 2002 |
Valdecoxib does not impair platelet function.
Topics: Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Bleeding Time; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Naproxen; Platelet Aggregation; Statistics, Nonparametric; Sulfonamides; Thromboxane B2 | 2002 |
Effects of cyclooxygenases inhibitors on vasoactive prostanoids and thrombin generation at the site of microvascular injury in healthy men.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Endothelium, Vascular; Fibrinolytic Agents; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Naproxen; Prostaglandin-Endoperoxide Synthases; Sulfones; Thrombin; Thromboxane B2 | 2003 |
Gastroduodenal tolerability of lumiracoxib vs placebo and naproxen: a pilot endoscopic study in healthy male subjects.
Topics: Adolescent; Adult; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Endoscopy, Gastrointestinal; Gastrointestinal Diseases; Humans; Intestinal Mucosa; Isoenzymes; Male; Membrane Proteins; Middle Aged; Naproxen; Organic Chemicals; Pilot Projects; Prostaglandin-Endoperoxide Synthases; Thromboxanes | 2003 |
Therapeutic arthritis research and gastrointestinal event trial of lumiracoxib - study design and patient demographics.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Health Status; Humans; Ibuprofen; Isoenzymes; Membrane Proteins; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Peptic Ulcer; Prognosis; Prostaglandin-Endoperoxide Synthases; Risk Factors | 2004 |
Risk of serious upper gastrointestinal and cardiovascular thromboembolic complications with meloxicam.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular System; Diclofenac; Dose-Response Relationship, Drug; Europe; Female; Gastrointestinal Diseases; Humans; Male; Meloxicam; Middle Aged; Naproxen; North America; Piroxicam; Risk Factors; Severity of Illness Index; Thiazines; Thiazoles; Thromboembolism; Time Factors; Treatment Failure; Upper Gastrointestinal Tract | 2004 |
Efficacy, safety and tolerability of lumiracoxib in patients with rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Organic Chemicals; Pain Measurement; Treatment Outcome | 2004 |
Valdecoxib is associated with improved dyspepsia-related health compared with nonspecific NSAIDs in patients with osteoarthritis or rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Dyspepsia; Female; Humans; Ibuprofen; Isoxazoles; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Patient Satisfaction; Placebos; Quality of Life; Sulfonamides; Treatment Outcome; Upper Gastrointestinal Tract | 2005 |
The post-operative analgesic efficacy and tolerability of lumiracoxib compared with placebo and naproxen after total knee or hip arthroplasty.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Naproxen; Organic Chemicals; Pain Measurement; Pain, Postoperative; Sample Size | 2005 |
Celecoxib versus naproxen and diclofenac in osteoarthritis patients: SUCCESS-I Study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Pyrazoles; Severity of Illness Index; Sulfonamides | 2006 |
The efficacy and safety of aceclofenac versus placebo and naproxen in women with primary dysmenorrhoea.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Dysmenorrhea; Female; Humans; Middle Aged; Naproxen; Pain Measurement; Self Administration; Treatment Outcome | 2006 |
Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Heart Defects, Congenital; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis | 2007 |
Effect of risk factors on complicated and uncomplicated ulcers in the TARGET lumiracoxib outcomes study.
Topics: Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Diclofenac; Duodenal Ulcer; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Risk Factors; Risk Reduction Behavior; Stomach Ulcer | 2007 |
Clinical trial: comparison of the gastrointestinal safety of lumiracoxib with traditional nonselective nonsteroidal anti-inflammatory drugs early after the initiation of treatment--findings from the Therapeutic Arthritis Research and Gastrointestinal Even
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Statistics as Topic | 2008 |
Less small-bowel injury with lumiracoxib compared with naproxen plus omeprazole.
Topics: Administration, Oral; Adult; Aged; Capsule Endoscopes; Cross-Over Studies; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Female; Humans; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Naproxen; Omeprazole; Probability; Reference Values; Risk Assessment; Ulcer | 2008 |
Efficacy and tolerability of lumiracoxib 200 mg once daily for treatment of primary dysmenorrhea: results from two randomized controlled trials.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Dysmenorrhea; Female; Humans; Middle Aged; Naproxen; Pain Measurement; Treatment Outcome | 2008 |
A comparison of the blood pressure changes of lumiracoxib with those of ibuprofen and naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Creatinine; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Pain Measurement | 2008 |
A randomised, double-blind study comparing lumiracoxib with naproxen for acute musculoskeletal pain.
Topics: Acute Disease; Adult; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Musculoskeletal Diseases; Naproxen; Pain; Treatment Outcome | 2008 |
A randomized, controlled study on the influence of acetaminophen, diclofenac, or naproxen on aspirin-induced inhibition of platelet aggregation.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Drug Interactions; Female; Humans; Male; Middle Aged; Naproxen; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Young Adult | 2009 |
Nonsteroidal anti-inflammatory drug hypersensitivity syndrome. A multicenter study. I. Clinical findings and in vitro diagnosis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Diclofenac; Drug Hypersensitivity; Female; Flow Cytometry; Humans; Leukotrienes; Lymphocyte Activation; Male; Middle Aged; Naproxen; ROC Curve; Sensitivity and Specificity; Young Adult | 2009 |
Kashin-Beck disease in Sichuan, China: report of a pilot open therapeutic trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; China; Diclofenac; Female; Glucosamine; Humans; Kashin-Beck Disease; Male; Middle Aged; Naproxen; Pain Measurement; Pilot Projects; Radiography; Self Care; Severity of Illness Index; Treatment Outcome | 2012 |
The effect of non-steroidal anti-inflammatory drugs on the endothelial function of patients with osteoarthritis in short term.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Brachial Artery; Cyclooxygenase Inhibitors; Diclofenac; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Naproxen; Nitroglycerin; Osteoarthritis; Prospective Studies; Treatment Outcome; Vasodilation | 2012 |
Comparison of the effect of naproxen, etodolac and diclofenac on postoperative sequels following third molar surgery: a randomised, double-blind, crossover study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diclofenac; Double-Blind Method; Edema; Etodolac; Female; Humans; Male; Molar, Third; Naproxen; Pain, Postoperative; Tooth Extraction; Tooth, Impacted; Trismus; Young Adult | 2014 |
Comparison of rectal indomethacin, diclofenac, and naproxen for the prevention of post endoscopic retrograde cholangiopancreatography pancreatitis.
Topics: Administration, Rectal; Adult; Aged; Amylases; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cholangiopancreatography, Endoscopic Retrograde; Diclofenac; Double-Blind Method; Eicosapentaenoic Acid; Female; Humans; Incidence; Indomethacin; Iran; Lipase; Lipoxins; Male; Middle Aged; Naproxen; Pancreatitis; Risk Factors; Time Factors; Treatment Outcome | 2017 |
Comparison of Clinical Efficacies of Preoperatively Initiated Naproxen Sodium-Codeine Phosphate in Combination, Diclofenac Potassium, and Benzydamine Hydrochloride for Pain, Edema, and Trismus After Extraction of Impacted Lower Third Molar: A Randomized D
Topics: Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Benzydamine; Codeine; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans; Male; Molar, Third; Naproxen; Pain, Postoperative; Preoperative Care; Tooth Extraction; Trismus; Young Adult | 2018 |
Long-Term Safety and Efficacy of Subcutaneous Tanezumab Versus Nonsteroidal Antiinflammatory Drugs for Hip or Knee Osteoarthritis: A Randomized Trial.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Blocking; Antibodies, Monoclonal, Humanized; Celecoxib; Diclofenac; Disease Progression; Double-Blind Method; Female; Fractures, Bone; Fractures, Spontaneous; Humans; Injections, Subcutaneous; Intra-Articular Fractures; Male; Middle Aged; Naproxen; Nerve Growth Factor; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteonecrosis; Treatment Outcome | 2021 |
Pharmacokinetic Interactions Between Tegoprazan and Naproxen, Aceclofenac, and Celecoxib in Healthy Korean Male Subjects.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Benzene Derivatives; Celecoxib; Cross-Over Studies; Diclofenac; Humans; Imidazoles; Male; Naproxen; Republic of Korea; Tablets | 2022 |
313 other study(ies) available for diclofenac and naproxen
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Nonsteroidal antiinflammatory agents. 14. Synthesis and pharmacological profile of 6-chloro-5-(cyclopentylmethyl)indan-1-carboxylic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Edema; Indans; Indenes; Male; Rats; Rats, Inbred Strains | 1984 |
1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Gastrointestinal Diseases; Humans; Imidazoles; Isoenzymes; Membrane Proteins; Mice; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Rats; Structure-Activity Relationship; Sulfonamides; Sulfones | 1997 |
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship | 2004 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclooxygenase Inhibitors; Disease Models, Animal; Flurbiprofen; Mice; Peptide Fragments | 2006 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.
Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water | 2006 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver.
Topics: Animals; Cells, Cultured; Child, Preschool; Chimera; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drugs, Investigational; Female; Half-Life; Hepatocytes; Humans; Immunomagnetic Separation; Liver; Male; Metabolic Clearance Rate; Mice; Mice, SCID; Recombinant Proteins; Species Specificity; Urokinase-Type Plasminogen Activator | 2012 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Design of novel potent antihyperlipidemic agents with antioxidant/anti-inflammatory properties: exploiting phenothiazine's strong antioxidant activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Atherosclerosis; Biphenyl Compounds; Carrageenan; Cholesterol, Dietary; Cyclooxygenase Inhibitors; Diet, High-Fat; Drug Design; Edema; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Hypolipidemic Agents; In Vitro Techniques; Indicators and Reagents; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Male; Mice; Microsomes; Phenothiazines; Picrates; Rats | 2014 |
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid | 2015 |
Structural Insights into the Competitive Binding of Diclofenac and Naproxen by Equine Serum Albumin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; Crystallization; Diclofenac; Horses; Models, Molecular; Naproxen; Protein Binding; Serum Albumin; Structure-Activity Relationship; X-Ray Diffraction | 2016 |
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hyperlipidemias; Hypolipidemic Agents; Morpholines; Rats; Triglycerides | 2016 |
Identification of small molecules that bind to the mitochondrial protein mitoNEET.
Topics: Hypoglycemic Agents; Ligands; Mitochondrial Proteins; Protein Binding; Small Molecule Libraries; Thiazolidinediones | 2016 |
1-Aryl-1H- and 2-aryl-2H-1,2,3-triazole derivatives blockade P2X7 receptor in vitro and inflammatory response in vivo.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Inflammation; Lipopolysaccharides; Mice; Molecular Structure; Pleurisy; Receptors, Purinergic P2X7; Structure-Activity Relationship; Triazoles | 2017 |
Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbonic Anhydrase Inhibitors; Humans; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides | 2018 |
The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Crystallography, X-Ray; Drug Design; Folic Acid; Folic Acid Antagonists; Humans; Models, Molecular; Tetrahydrofolate Dehydrogenase | 2020 |
[Anti-edematous, anti-inflammatory and analgesics activity of fentiazac, naproxen and diclofenac sodium].
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Edema; Mice; Naproxen; Peritonitis; Phenylacetates; Pleurisy; Rats; Thiazoles | 1977 |
Asthmatic attacks induced in aspirin-sensitive patients by diclofenac and naproxen.
Topics: Adult; Aspirin; Asthma; Cyclooxygenase Inhibitors; Diclofenac; Drug Hypersensitivity; Female; Humans; Male; Naphthaleneacetic Acids; Naproxen; Phenylacetates | 1977 |
Comparisons of tolerability findings in international clinical trials.
Topics: Arthritis, Rheumatoid; Aspirin; Cardiovascular System; Clinical Trials as Topic; Diclofenac; Drug Tolerance; Follow-Up Studies; Gastrointestinal Diseases; Hematologic Tests; Humans; Ibuprofen; Indomethacin; International Cooperation; Naproxen; Phenylacetates; Time Factors | 1979 |
[On the efficiency of new antiinflammatory agents. A comparative study (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Benzylidene Compounds; Carrageenan; Diclofenac; Edema; Fenoprofen; In Vitro Techniques; Indenes; Indomethacin; Ketoprofen; Naproxen; Phenylbutazone; Protease Inhibitors; Rats | 1977 |
In vivo inhibition of prostaglandin synthesis in rabbit kidney by non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Diclofenac; Dose-Response Relationship, Drug; Indomethacin; Injections, Intravenous; Kidney; Kidney Medulla; Male; Naproxen; Prostaglandins E; Prostaglandins F; Rabbits; Time Factors | 1978 |
Dose-dependent inhibition of sensory nerve activity in the feline dental pulp by anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Cats; Dental Pulp; Diclofenac; Dose-Response Relationship, Drug; Hot Temperature; Indomethacin; Injections, Intravenous; Methysergide; Naproxen; Nerve Endings; Sensory Receptor Cells | 1978 |
Inhibition of prostaglandin synthesis in rat brain.
Topics: Acetaminophen; Animals; Aspirin; Brain; Diclofenac; Dose-Response Relationship, Drug; Indomethacin; Male; Naproxen; Prostaglandin Antagonists; Prostaglandins E; Prostaglandins F; Rats; Time Factors | 1978 |
Anti-inflammatory activity of BF389, a Di-T-butylphenol, in animal models of arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis, Experimental; Collagen; Diamines; Diclofenac; Dinoprostone; Disease Models, Animal; Female; Interleukin-1; Leukotriene B4; Male; Naproxen; Oxazines; Phenols; Piroxicam; Rats; Rats, Inbred Lew; Thromboxane B2 | 1992 |
Measurement of non-steroid antiinflammatory drugs induced gastric microbleeding.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Apazone; Diclofenac; Gastric Juice; Gastrointestinal Hemorrhage; Humans; Indomethacin; Middle Aged; Naproxen | 1992 |
High-performance liquid chromatographic determination of naproxen, ibuprofen and diclofenac in plasma and synovial fluid in man.
Topics: Chromatography, High Pressure Liquid; Diclofenac; Humans; Ibuprofen; Naproxen; Reproducibility of Results; Spectrophotometry, Ultraviolet; Synovial Fluid | 1992 |
The economic consequences of NSAID-induced gastropathy: the French context.
Topics: Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Cost of Illness; Diclofenac; Duodenal Ulcer; Economics, Hospital; Etodolac; France; Gastrointestinal Diseases; Humans; Ketoprofen; Naproxen; National Health Programs; Piroxicam; Rheumatic Diseases; Sulindac | 1992 |
Liver disease associated with diclofenac, naproxen, and piroxicam.
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Child; Diclofenac; Female; Follow-Up Studies; Humans; Male; Middle Aged; Naproxen; Piroxicam; Product Surveillance, Postmarketing; Risk Factors; United Kingdom | 1992 |
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoquinones; Capillary Permeability; Carrageenan; Diclofenac; Edema; Female; Granuloma; Indomethacin; Male; Mice; Naproxen; Pain; Phenylbutazone; Pleurisy; Rats; Rats, Inbred Strains; Silver Nitrate; Stomach Ulcer; Synovitis | 1991 |
Pseudoallergic reactions to nonsteroidal anti-inflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Drug Eruptions; Female; Flurbiprofen; Humans; Naproxen | 1991 |
A prospective nationwide cross-sectional study of NSAID usage in 1331 patients with ankylosing spondylitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cross-Sectional Studies; Diclofenac; Female; Gold; Humans; Ibuprofen; Male; Methotrexate; Middle Aged; Naproxen; Penicillamine; Piroxicam; Prednisolone; Prospective Studies; Spondylitis, Ankylosing; Sulfasalazine; United Kingdom | 1990 |
The pharmacological profile of aceclofenac, a new nonsteroidal antiinflammatory and analgesic drug.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dogs; Female; Indomethacin; Male; Mice; Naproxen; Phenylbutazone; Rats; Rats, Inbred Strains; Stomach Ulcer | 1991 |
Ketoprofen vs naproxen or diclofenac sodium in osteoarthritis.
Topics: Diclofenac; Humans; Ketoprofen; Multicenter Studies as Topic; Naproxen; Osteoarthritis | 1990 |
Induction of cleft palate in mice by inhibitors of prostaglandin synthesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cleft Palate; Diclofenac; Female; Indomethacin; Injections, Intramuscular; Maternal-Fetal Exchange; Mice; Microscopy; Naproxen; Organ Culture Techniques; Palate; Pregnancy; Sulindac | 1990 |
[Efficacy of sucralfate in the prevention of stomach diseases induced by non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Piroxicam; Stomach Diseases; Sucralfate; Time Factors | 1989 |
[Evolution of enzymuria in the course of acute renal insufficiency caused by non-steroidal anti-inflammatory agents].
Topics: Acetylglucosaminidase; Acute Kidney Injury; Aged; Aged, 80 and over; Aminopeptidases; Anti-Inflammatory Agents, Non-Steroidal; CD13 Antigens; Diclofenac; Female; gamma-Glutamyltransferase; Hexosaminidases; Humans; Indomethacin; Middle Aged; Naproxen | 1989 |
Effect of diclofenac sodium on the arachidonic acid cascade.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Lipoxygenase Inhibitors; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Naproxen; Phospholipids; Piroxicam; Prostaglandins E; Rats; SRS-A; Thiazines; Triglycerides | 1986 |
The history of diclofenac.
Topics: Chemical Phenomena; Chemistry; Diclofenac; Humans; Hydrogen-Ion Concentration; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Naproxen; Phenylbutazone; Piroxicam; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Thiazines | 1986 |
Topical non-steroidal anti-inflammatory drugs inhibit non-immunologic immediate contact reactions.
Topics: Acrolein; Adult; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Benzoic Acid; Dermatitis, Contact; Diclofenac; Dimethyl Sulfoxide; Female; Humans; Irritants; Male; Naproxen; Nicotinic Acids; Regional Blood Flow; Salicylates; Skin | 1988 |
Comparison of the effects of different anti-inflammatory drugs on synovial fluid prostanoid concentrations in patients with rheumatoid arthritis.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Dinoprostone; Guanidines; Humans; Indomethacin; Naproxen; ortho-Aminobenzoates; Prednisolone; Prostaglandins; Prostaglandins E; Quinazolines; Synovial Fluid; Thromboxane B2 | 1985 |
The history of diclofenac.
Topics: Diclofenac; History, 20th Century; Ibuprofen; Ketoprofen; Models, Molecular; Naproxen; Phenylbutazone; Piroxicam; Solubility; Structure-Activity Relationship; Thiazines | 1985 |
The effects of diclofenac sodium on arachidonic acid metabolism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Leukocytes; Lipoxygenase; Naproxen; Phospholipases A; Phospholipases A2; Phospholipids; Piroxicam; Prostaglandins E; SRS-A; Thiazines; Triglycerides | 1985 |
Effects of diclofenac sodium on arachidonic acid metabolism.
Topics: Arachidonic Acid; Arachidonic Acids; Diclofenac; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Monocytes; Naproxen; Neutrophils; Piroxicam; SRS-A; Thiazines | 1985 |
Worldwide experience with diclofenac in rheumatoid arthritis and osteoarthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Diclofenac; Double-Blind Method; Humans; Indomethacin; Naproxen; Osteoarthritis; Sulindac; Tolmetin | 1985 |
Diclofenac sodium in the treatment of rheumatoid arthritis and osteoarthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Pain | 1985 |
Diclofenac in the treatment of painful joints and traumatic tendinitis (including strains and sprains): a brief review.
Topics: Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Joint Diseases; Ketoprofen; Naproxen; Pain; Sprains and Strains; Tendinopathy | 1985 |
Effect on platelet aggregation of oral administration of 10 non-steroidal analgesics to humans.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Diclofenac; Diflunisal; Epinephrine; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Oxyphenbutazone; Piroxicam; Platelet Aggregation; Thiazines; Time Factors | 1984 |
Osteoarthritis and non-steroidal and anti-inflammatory drugs: a multi-centre comparative study.
Topics: Aged; Diclofenac; Female; Hip Joint; Humans; Ibuprofen; Indenes; Knee Joint; Male; Naproxen; Osteoarthritis; Sulindac | 1982 |
Diclofenac sodium, diflunisal and naproxen: patient preferences for anti-inflammatory drugs in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Consumer Behavior; Diclofenac; Diflunisal; Female; Humans; Male; Middle Aged; Naproxen; Patient Participation; Phenylacetates; Salicylates | 1982 |
[Comparison of 3 therapeutic regimes using non-steroidal antirheumatic agents in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Diclofenac; Female; Humans; Male; Middle Aged; Naproxen; Phenylacetates; Suppositories; Tablets | 1981 |
Renal prostaglandins and sodium balance in the rabbit: lack of effect of aspirin-like drugs.
Topics: Aldosterone; Animals; Anti-Inflammatory Agents; Aspirin; Diclofenac; Diet, Sodium-Restricted; Female; Indomethacin; Kidney; Mineralocorticoid Receptor Antagonists; Naproxen; Potassium; Prostaglandins E; Prostaglandins F; Rabbits; Sodium | 1980 |
Submicron emulsion vehicle for enhanced transdermal delivery of steroidal and nonsteroidal antiinflammatory drugs.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Indomethacin; Naproxen; Piroxicam; Rats; Rats, Sprague-Dawley; Skin; Steroids; Time Factors | 1995 |
NSAIDs, Cox-2 inhibitors, and the gut.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cyclooxygenase Inhibitors; Diclofenac; Digestive System; Humans; Indans; Nabumetone; Naproxen; Oxidative Phosphorylation; Piroxicam; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases | 1995 |
Histological findings in gastric mucosa in patients treated with non-steroidal anti-inflammatory drugs.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Female; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Ketoprofen; Male; Middle Aged; Naproxen; Osteoarthritis | 1995 |
Nonsteroidal antiinflammatory drugs: effects on normal and interleukin 1 treated human articular chondrocyte metabolism in vitro.
Topics: Cartilage, Articular; Cell Division; Cells, Cultured; Collagenases; Diclofenac; Dinoprostone; Extracellular Matrix; Humans; Ibuprofen; Interleukin-1; Interleukin-6; Naproxen; Reference Values; Salicylates | 1995 |
Alterations in the electroretinogram of newborn piglets by propionic acid-derivative nonsteroidal antiinflammatory drugs but not by indomethacin and diclofenac.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electroretinography; Flurbiprofen; Ibuprofen; Indomethacin; Naproxen; Photoreceptor Cells; Propionates; Prostaglandins; Retina; Swine | 1995 |
Effect of etodolac on prostaglandin E2 biosynthesis, active oxygen generation and bradykinin formation.
Topics: Animals; Aspirin; Bradykinin; Bromelains; Cartilage, Articular; Cell Line; Concanavalin A; Depression, Chemical; Diclofenac; Dinoprostone; Dogs; Etodolac; Gastric Mucosa; Guinea Pigs; Indomethacin; Interleukin-1; Ketoprofen; Kidney; Naproxen; Oxygen; Pain; Piroxicam; Rabbits; Rats | 1994 |
The infrequency of liver function testing in patients using nonsteroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Health Maintenance Organizations; Humans; Liver Function Tests; Lovastatin; Male; Middle Aged; Naproxen; Piroxicam; Probability; Time Factors | 1995 |
Renal impairment after acute diclofenac, naproxen, and sulindac overdoses.
Topics: Acute Kidney Injury; Adolescent; Adult; Alcoholic Intoxication; Creatinine; Diclofenac; Drug Interactions; Female; Humans; Male; Middle Aged; Naproxen; Sulindac | 1995 |
Antinociceptive effects of non-steroidal anti-inflammatory drugs in a rat model of unilateral hindpaw inflammation.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Inflammation; Injections, Intramuscular; Male; Naphthaleneacetic Acids; Naproxen; Pain; Rats; Rats, Wistar | 1994 |
Gastric mucosal damage induced by nonsalicylate nonsteroidal antiinflammatory drugs in rats is mediated systemically.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Gastric Mucosa; Indomethacin; Male; Naproxen; Rats; Rats, Wistar | 1993 |
Effect of tenidap on cartilage integrity in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cattle; Diclofenac; Glycosaminoglycans; Indoles; Interleukin-1; Naproxen; Organ Culture Techniques; Oxindoles; Recombinant Proteins; Swine; Synovial Membrane | 1993 |
Do non-steroidal anti-inflammatory drugs have an effect on gastric cell turnover?
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Bromodeoxyuridine; Cell Division; Diclofenac; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Immunohistochemistry; Indomethacin; Mefenamic Acid; Naproxen; Pyloric Antrum | 1995 |
Comparative effects of nabumetone, naproxen, piroxicam, and diclofenac on rat gastric irritancy following acute exposure to OTC non-steroidal anti-inflammatory agents and other gastric irritants.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Diclofenac; Gastric Mucosa; Male; Nabumetone; Naproxen; Nonprescription Drugs; Piroxicam; Rats; Rats, Wistar | 1995 |
Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dermatitis, Phototoxic; Diclofenac; Erythrocytes; Hemolysis; Humans; Ibuprofen; In Vitro Techniques; Ketoprofen; Light; Naproxen; Phenylbutazone; Photosensitizing Agents; Piroxicam; Propionates | 1996 |
Histamine H2-receptor antagonist action of ebrotidine. Effects on gastric acid secretion, gastrin levels and NSAID-induced gastrotoxicity in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulfonates; Diclofenac; Dose-Response Relationship, Drug; Female; Gastric Acid; Gastrins; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Ketoprofen; Male; Naproxen; Pentagastrin; Ranitidine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thiazoles | 1997 |
Effects of the combined oral administration of NSAIDs and dextromethorphan on behavioral symptoms indicative of arthritic pain in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Behavior, Animal; Dextromethorphan; Diclofenac; Drug Interactions; Drug Therapy, Combination; Etodolac; Ibuprofen; Injections, Intraperitoneal; Male; Naproxen; Pain; Piroxicam; Rats; Rats, Sprague-Dawley | 1996 |
Determination of diclofenac in micro-whole blood samples by high-performance liquid chromatography with electrochemical detection. Application in a pharmacokinetic study.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Diclofenac; Electrochemistry; Half-Life; Male; Naproxen; Rats; Rats, Wistar | 1997 |
Serum protein binding of nonsteroidal antiinflammatory drugs: a comparative study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chromatography, High Pressure Liquid; Diclofenac; Female; Fenoprofen; Flurbiprofen; Humans; Ketoprofen; Male; Middle Aged; Naproxen; Protein Binding; Tolmetin | 1997 |
The influence of age, gender, Helicobacter pylori and smoking on gastric mucosal adaptation to non-steroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Tolerance; Etodolac; Female; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Naproxen; Retrospective Studies; Sex Factors; Smoking; Stomach Diseases | 1997 |
Development of an HPLC assay to study the effect of endogenous and exogenous substances on heat-induced aggregation of human serum albumin.
Topics: Acids, Acyclic; Albumins; Anti-Inflammatory Agents, Non-Steroidal; Bilirubin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dicarboxylic Acids; Diclofenac; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Humans; Ibuprofen; In Vitro Techniques; Naproxen; Nephelometry and Turbidimetry; Protein Denaturation; Serum Albumin; Sodium Chloride | 1998 |
Partial-solubility parameters of naproxen and sodium diclofenac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Diclofenac; Naproxen; Solubility; Solvents | 1998 |
Low-dose diclofenac, naproxen, and ibuprofen cohort study.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cohort Studies; Diclofenac; Dose-Response Relationship, Drug; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Female; Gastrointestinal Hemorrhage; Hematologic Diseases; Humans; Ibuprofen; Male; Middle Aged; Naproxen | 1999 |
Cleavage of tertiary amidomethyl ester prodrugs of carboxylic acids by rat liver homogenates.
Topics: Amides; Animals; Benzoic Acid; Carboxylic Acids; Clofibric Acid; Diclofenac; Drug Interactions; Esters; Hydrolases; Hydrolysis; Ibuprofen; In Vitro Techniques; Liver; Male; Naproxen; Physostigmine; Proadifen; Probenecid; Prodrugs; Rats; Rats, Sprague-Dawley; Refractometry; Solubility; Structure-Activity Relationship; Time Factors; Valproic Acid | 1999 |
Pharmacoepidemiology of non-steroidal anti-inflammatory drug use in Nottingham general practices.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Prescriptions; Family Practice; Humans; Ibuprofen; Inflammation; Medical Records Systems, Computerized; Middle Aged; Naproxen; Patient Compliance; Pharmacoepidemiology; United Kingdom | 2000 |
Ibuprofen versus other non-steroidal anti-inflammatory drugs: use in general practice and patient perception.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Prescriptions; Humans; Ibuprofen; Medical Records Systems, Computerized; Middle Aged; Naproxen; Patient Satisfaction; Surveys and Questionnaires; United Kingdom | 2000 |
Preference for nonsteroidal antiinflammatory drugs versus acetaminophen and concomitant use of both types of drugs in patients with osteoarthritis.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Data Collection; Diclofenac; Female; Humans; Ibuprofen; Male; Naproxen; Osteoarthritis; Patient Satisfaction; Self Administration; Surveys and Questionnaires | 2000 |
[Is homeopathic medicine equivalent to diclofenac?! An opinion statement against misleading].
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Double-Blind Method; Homeopathy; Humans; Hyaluronic Acid; Naproxen; Placebos; Randomized Controlled Trials as Topic; Time Factors | 2000 |
The risk of gastrointestinal bleed, myocardial infarction, and newly diagnosed hypertension in users of meloxicam, diclofenac, naproxen, and piroxicam.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Databases, Factual; Diclofenac; Gastrointestinal Hemorrhage; Humans; Hypertension; Isoenzymes; Meloxicam; Membrane Proteins; Myocardial Infarction; Naproxen; Piroxicam; Prostaglandin-Endoperoxide Synthases; Risk Assessment; Thiazines; Thiazoles; United Kingdom | 2000 |
Inhibition of tendon cell proliferation and matrix glycosaminoglycan synthesis by non-steroidal anti-inflammatory drugs in vitro.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Culture Techniques; Diclofenac; Female; Glycosaminoglycans; Humans; Indomethacin; Male; Middle Aged; Naproxen; Tendons; Wound Healing | 2001 |
[Two complex suicidal poisonings with drugs and their medicolegal aspects].
Topics: Adult; Atenolol; Chromatography, High Pressure Liquid; Diclofenac; Estazolam; Fatal Outcome; Female; Humans; Ibuprofen; Illicit Drugs; Ketoprofen; Male; Metronidazole; Naproxen; Poland; Suicide, Attempted; Theophylline; Tolperisone | 2001 |
In vitro and in vivo evaluation of polyoxyethylene esters as dermal prodrugs of ketoprofen, naproxen and diclofenac.
Topics: Administration, Cutaneous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Diclofenac; Erythema; Female; Gels; Humans; Ketoprofen; Male; Middle Aged; Naproxen; Polyethylene Glycols; Prodrugs; Skin Absorption; Solubility; Solvents | 2001 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Etodolac; Humans; Ibuprofen; Indomethacin; Ketorolac; Lactones; Nabumetone; Naproxen; Pain, Postoperative; Piroxicam; Pyrazoles; Sulfonamides; Sulfones; Time Factors | 2001 |
[Renal tolerance of selective inhibitors of cyclooxygenase type 2].
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Celecoxib; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Diclofenac; Humans; Kidney; Kidney Diseases; Lactones; Naproxen; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Risk Factors; Sulfonamides; Sulfones; Water-Electrolyte Imbalance | 2001 |
Celecoxib in osteoarthritis and rheumatoid arthritis: new preparation. As disappointing as rofecoxib.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; France; Humans; Naproxen; Osteoarthritis; Sulfonamides; Treatment Outcome | 2001 |
Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Energy Transfer; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Ketoprofen; Meclofenamic Acid; Mefenamic Acid; Membrane Proteins; Models, Molecular; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2002 |
Influence of irradiation sterilization on poly(lactide-co-glycolide) microspheres containing anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Diclofenac; Drug Delivery Systems; Naproxen; Polyglactin 910; Sterilization; Technology, Pharmaceutical | 2002 |
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Diclofenac; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Epithelial Cells; Fallopian Tubes; Female; Histamine; Humans; Ibuprofen; Indomethacin; Inflammation Mediators; Muscle Contraction; Muscle, Smooth; Naproxen; Pelvic Pain; Platelet Activating Factor | 2002 |
Oligoethylene ester derivatives of ketoprofen, naproxen and diclofenac as oral prodrugs: a pharmacological evaluation.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Edema; Esters; Hydrolysis; Ketoprofen; Male; Mice; Naproxen; Pain Measurement; Pharmaceutical Vehicles; Polyethylene Glycols; Prodrugs; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2002 |
Differential effects of nonsteroidal antiinflammatory drugs on the IL-1 altered expression of plasminogen activators and plasminogen activator inhibitor-1 by articular chondrocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Cells, Cultured; Chondrocytes; Diclofenac; Dose-Response Relationship, Drug; Gene Expression Regulation; Indomethacin; Interleukin-1; Meloxicam; Naproxen; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Propionates; RNA, Messenger; Thiazines; Thiazoles | 2002 |
Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Gemfibrozil; Hydrogen-Ion Concentration; Hydroxides; Ibuprofen; Naproxen; ortho-Aminobenzoates; Phenylacetates; Valproic Acid | 2001 |
Pathogenic importance of intestinal hypermotility in NSAID-induced small intestinal damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dinoprostone; Flurbiprofen; Gastrointestinal Motility; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Naproxen; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Sprague-Dawley | 2002 |
Rofecoxib in rheumatoid arthritis: new indication. No better that other NSAIDS.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Contraindications; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Lactones; Naproxen; Sulfonamides; Treatment Outcome; United States | 2003 |
Persistence with COX-2 inhibitors in managed care: an analysis of claims data.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Utilization Review; Female; Health Care Costs; Humans; Ibuprofen; Insurance Claim Review; Isoenzymes; Lactones; Male; Managed Care Programs; Membrane Proteins; Middle Aged; Naproxen; Patient Compliance; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Regression Analysis; Sulfonamides; Sulfones; United States | 2003 |
[Pain therapy in rheumatism. After 65 years of age coxibs are the best choice].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Cyclooxygenase Inhibitors; Diclofenac; Gastrointestinal Hemorrhage; Humans; Isoxazoles; Naproxen; Prognosis; Rheumatic Diseases; Sulfonamides | 2003 |
Potential interaction between acenocoumarol and diclofenac, naproxen and ibuprofen and role of CYP2C9 genotype.
Topics: Acenocoumarol; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Chi-Square Distribution; Cohort Studies; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; Drug Interactions; Female; Genotype; Humans; Ibuprofen; International Normalized Ratio; Male; Middle Aged; Naproxen; Retrospective Studies; Sex Factors; Time Factors; Warfarin | 2004 |
Application of capillary electrophoresis with different sample stacking strategies for the determination of a group of nonsteroidal anti-inflammatory drugs in the low microg x L(-1) concentration range.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrophoresis, Capillary; Fenoprofen; Ibuprofen; Ketoprofen; Naproxen; Water | 2004 |
Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9).
Topics: Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Base Sequence; Binding Sites; Cytochrome P-450 CYP2C9; Diclofenac; Escherichia coli; Gene Expression; Hemeproteins; Holoenzymes; Humans; Ibuprofen; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Naproxen; Peptide Fragments; Recombinant Proteins; Sequence Homology, Nucleic Acid; Substrate Specificity | 2004 |
A population based historical cohort study of the mortality associated with nabumetone, Arthrotec, diclofenac, and naproxen.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cause of Death; Chronic Disease; Cohort Studies; Diclofenac; Drug Combinations; Female; Humans; Logistic Models; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Risk; Saskatchewan; Survival Rate | 2004 |
Nonsteroidal antiinflammatory drugs and the risk of myocardial infarction in the general population.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiotonic Agents; Case-Control Studies; Cohort Studies; Comorbidity; Coronary Disease; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Drug Synergism; Drug Utilization; Female; Follow-Up Studies; Humans; Ibuprofen; Lactones; Male; Middle Aged; Myocardial Infarction; Naproxen; Odds Ratio; Risk Factors; Spain; Sulfones | 2004 |
The flow-cytometric determination of basophil activation induced by aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is useful for in vitro diagnosis of the NSAID hypersensitivity syndrome.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Basophil Degranulation Test; Basophils; Diclofenac; Dipyrone; Drug Hypersensitivity; Female; Flow Cytometry; Humans; Male; Middle Aged; Naproxen; Predictive Value of Tests; Sensitivity and Specificity; Urticaria | 2004 |
Evidence in practice--number 3: Cox 2 inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Evidence-Based Medicine; Humans; Ibuprofen; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Stomach Ulcer | 2004 |
Sulfone COX-2 inhibitors increase susceptibility of human LDL and plasma to oxidative modification: comparison to sulfonamide COX-2 inhibitors and NSAIDs.
Topics: Animals; Antioxidants; Celecoxib; Cholesterol, LDL; Chromans; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Isoprostanes; Isoxazoles; Lactones; Meloxicam; Naproxen; Oxidation-Reduction; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2004 |
In vitro inhibitory effects of non-steroidal antiinflammatory drugs on UDP-glucuronosyltransferase 1A1-catalysed estradiol 3beta-glucuronidation in human liver microsomes.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Evaluation, Preclinical; Estradiol; Estrogen Antagonists; Glucuronides; Glucuronosyltransferase; Humans; Inhibitory Concentration 50; Microsomes, Liver; Naproxen | 2005 |
Recombinant human lactoferrin prevents NSAID-induced intestinal bleeding in rodents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gastrointestinal Hemorrhage; Humans; Indomethacin; Lactoferrin; Male; Naproxen; Pain Measurement; Protein Binding; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2005 |
Tracking acidic pharmaceuticals, caffeine, and triclosan through the wastewater treatment process.
Topics: Caffeine; Diclofenac; Ibuprofen; Ketoprofen; Meclofenamic Acid; Models, Chemical; Naproxen; Pharmaceutical Preparations; Triclosan; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Patients exposed to rofecoxib and celecoxib have different odds of nonfatal myocardial infarction.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bias; Case-Control Studies; Celecoxib; Confounding Factors, Epidemiologic; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Lactones; Male; Middle Aged; Myocardial Infarction; Naproxen; Odds Ratio; Pyrazoles; Risk Factors; Sulfonamides; Sulfones | 2005 |
Cellular mechanisms of acetaminophen: role of cyclo-oxygenase.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cell Line; Cyclooxygenase Inhibitors; Diclofenac; Enzyme Activation; Humans; Ibuprofen; Indomethacin; Lactones; Lung; Naproxen; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; Sulfones; tert-Butylhydroperoxide; Transcription, Genetic | 2005 |
Measuring the mass of an electron by LC/TOF-MS: a study of "twin ions".
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Carbon Dioxide; Chromatography, Liquid; Diclofenac; Electrons; Formates; Ibuprofen; Ions; Naproxen; Protons; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Occurrence of acidic pharmaceuticals in raw and treated sewages and in receiving waters.
Topics: Bezafibrate; Diclofenac; Environmental Pollutants; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Molecular Structure; Naproxen; Sewage; Water | 2005 |
Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and their occurrence in municipal wastewater treated by a membrane bioreactor.
Topics: Aerobiosis; Amides; Bezafibrate; Biodegradation, Environmental; Bioreactors; Cities; Diclofenac; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Sewage; Spectrometry, Mass, Electrospray Ionization; Time Factors; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Prediction of CYP2C9-mediated drug-drug interactions: a comparison using data from recombinant enzymes and human hepatocytes.
Topics: Amiodarone; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Cytochrome P-450 CYP2C9; Diclofenac; Drug Interactions; Enzyme Inhibitors; Hepatocytes; Humans; In Vitro Techniques; Kinetics; Naproxen; Recombinant Proteins; Reproducibility of Results | 2005 |
Role of monocarboxylic acid transporters in the cellular uptake of NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzoic Acid; Caco-2 Cells; Carbon Radioisotopes; Diclofenac; Diflunisal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Ketoprofen; Lactic Acid; Monocarboxylic Acid Transporters; Naproxen; Permeability | 2005 |
Is there an association between the use of different types of nonsteroidal antiinflammatory drugs and radiologic progression of osteoarthritis? The Rotterdam Study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Disease Progression; Female; Follow-Up Studies; Humans; Ibuprofen; Logistic Models; Male; Middle Aged; Naproxen; Netherlands; Osteoarthritis, Hip; Osteoarthritis, Knee; Pharmacies; Piroxicam; Radiography; Risk Factors | 2005 |
Pharmacokinetic interaction of tetracycline with non-steroidal anti-inflammatory drugs via organic anion transporters in rats.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Interactions; Male; Metabolic Clearance Rate; Naproxen; Organic Anion Transporters; Rats; Rats, Sprague-Dawley; Tetracycline | 2006 |
Risk of hospitalization with peptic ulcer disease or gastrointestinal hemorrhage associated with nabumetone, Arthrotec, diclofenac, and naproxen in a population based cohort study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cohort Studies; Databases, Factual; Diclofenac; Drug Combinations; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Peptic Ulcer; Risk Factors; Saskatchewan | 2005 |
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
Topics: Aspirin; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Celecoxib; Cell Line; Cerebrospinal Fluid Proteins; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indomethacin; Ionophores; Lactones; Meloxicam; Naproxen; Organ Specificity; Organic Chemicals; Protein Binding; Pyrazoles; Sodium Salicylate; Sulfonamides; Sulfones; Synovial Fluid; Thiazines; Thiazoles; Thromboxane A2 | 2006 |
Selected Rofams as a micellar solubilizers for diclofenac and naproxen in the environment of the standard vehicle for eye drops.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Micelles; Naproxen; Ophthalmic Solutions; Pharmaceutical Vehicles; Solubility; Solutions; Water | 2005 |
Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Colitis, Ulcerative; Crohn Disease; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Indomethacin; Inflammatory Bowel Diseases; Male; Middle Aged; Nabumetone; Naproxen; Prevalence; Recurrence; Sulfonamides | 2006 |
Nonsteroidal anti-inflammatory drug use in ankylosing spondylitis--a population-based survey.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cohort Studies; Cross-Sectional Studies; Diclofenac; Female; Humans; Indomethacin; Male; Middle Aged; Naproxen; Pain; Pain Measurement; Patient Satisfaction; Pyrazoles; Retreatment; Spondylitis, Ankylosing; Sulfonamides; Surveys and Questionnaires; Treatment Outcome | 2006 |
Effect of glutamate receptor antagonists and antirheumatic drugs on proliferation of synoviocytes in vitro.
Topics: Animals; Antirheumatic Agents; Benzodiazepines; Benzodiazepinones; Celecoxib; Cell Line; Cell Proliferation; Cell Survival; Diclofenac; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Inhibitory Concentration 50; Methotrexate; Naproxen; Pyrazoles; Quinoxalines; Sulfasalazine; Sulfonamides; Synovial Membrane | 2006 |
Quantitative assessment of the gastrointestinal and cardiovascular risk-benefit of celecoxib compared to individual NSAIDs at the population level.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Celecoxib; Computer Simulation; Coronary Disease; Cyclooxygenase Inhibitors; Diclofenac; Female; Heart Failure; Humans; Ibuprofen; Male; Middle Aged; Models, Statistical; Naproxen; Peptic Ulcer; Population Surveillance; Pyrazoles; Risk Assessment; Risk Factors; Stroke; Sulfonamides; United States | 2007 |
Factors involved in upregulation of inducible nitric oxide synthase in rat small intestine following administration of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Disease Models, Animal; Enterobacteriaceae; Flurbiprofen; Gastrointestinal Motility; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Lactones; Male; Naproxen; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfones; Time Factors; Up-Regulation | 2006 |
Synthesis of 1-beta-O-acyl glucuronides of diclofenac, mefenamic acid and (S)-naproxen by the chemo-selective enzymatic removal of protecting groups from the corresponding methyl acetyl derivatives.
Topics: Acylation; Carbohydrate Conformation; Chromatography, High Pressure Liquid; Diclofenac; Glucuronides; Hydrolysis; Kinetics; Mefenamic Acid; Methylation; Models, Molecular; Naproxen | 2006 |
Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Lactones; Male; Multivariate Analysis; Myocardial Infarction; Naproxen; Pyrazoles; Rheumatic Diseases; Risk Assessment; Risk Factors; Sulfonamides; Sulfones | 2006 |
Solid molecular dispersions of poorly water-soluble drugs in poly(2-hydroxyethyl methacrylate) hydrogels.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Crystallography, X-Ray; Diclofenac; Drug Carriers; Drug Compounding; Drug Stability; Drug Storage; Humidity; Hydrogels; Naproxen; Phase Transition; Piroxicam; Polyhydroxyethyl Methacrylate; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Time Factors; Water | 2007 |
Micellar solubilization of selected non-steroidal therapeutic agents by new surface-active agents of the class of the products of oxyethylation of ursodeoxycholic acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Ketoprofen; Micelles; Naproxen; Pharmaceutical Preparations; Solubility; Solutions; Surface-Active Agents; Ursodeoxycholic Acid; Viscosity | 2006 |
[By what means does the rheumatic patient with gastrointestinal risks fare best?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Controlled Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Etoricoxib; Gastrointestinal Diseases; Germany; Humans; Naproxen; Osteoarthritis; Proton Pump Inhibitors; Pyridines; Rheumatic Diseases; Risk Factors; Sulfones; United States | 2007 |
An economic model of long-term use of celecoxib in patients with osteoarthritis.
Topics: Age Factors; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cost-Benefit Analysis; Diclofenac; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Long-Term Care; Male; Maximum Tolerated Dose; Middle Aged; Models, Economic; Naproxen; Osteoarthritis; Probability; Pyrazoles; Quality-Adjusted Life Years; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Sulfonamides | 2007 |
Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Case-Control Studies; Celecoxib; Cytochrome P-450 CYP2C9; Diclofenac; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Odds Ratio; Peptic Ulcer; Peptic Ulcer Hemorrhage; Piroxicam; Polymorphism, Single Nucleotide; Pyrazoles; Risk Assessment; Risk Factors; Sulfonamides | 2007 |
Photocatalytic degradation of non-steroidal anti-inflammatory drugs with TiO2 and simulated solar irradiation.
Topics: Aliivibrio fischeri; Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Diclofenac; Ibuprofen; Luminescence; Naproxen; Photolysis; Sunlight; Titanium; Water Pollutants, Chemical | 2008 |
Etoricoxib: new drug. Avoid using cox-2 inhibitors for pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Gastrointestinal Diseases; Gout; Humans; Ibuprofen; Naproxen; Pain; Pyridines; Sulfones | 2007 |
Cyclooxygenase-2 inhibitors and most traditional nonsteroidal anti-inflammatory drugs cause similar moderately increased risks of cardiovascular disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Humans; Ibuprofen; Meta-Analysis as Topic; Myocardial Infarction; Naproxen; Risk | 2008 |
Identification and quantification of ibuprofen, naproxen, ketoprofen and diclofenac present in waste-waters, as their trimethylsilyl derivatives, by gas chromatography mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gas Chromatography-Mass Spectrometry; Hungary; Ibuprofen; Ketoprofen; Naproxen; Trimethylsilyl Compounds; Waste Disposal, Fluid; Water Pollutants, Chemical | 2008 |
Does the varied use of NSAIDs explain the differences in the risk of myocardial infarction?
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Administration Schedule; Epidemiologic Methods; Female; Humans; Ibuprofen; Male; Middle Aged; Myocardial Infarction; Naproxen; Sex Factors; Time Factors | 2008 |
Advances in stir bar sorptive extraction for the determination of acidic pharmaceuticals in environmental water matrices Comparison between polyurethane and polydimethylsiloxane polymeric phases.
Topics: Chromatography, High Pressure Liquid; Diclofenac; Dimethylpolysiloxanes; Gemfibrozil; Ibuprofen; Mefenamic Acid; Naproxen; Polyurethanes; Reproducibility of Results; Water Pollutants, Chemical; Water Purification | 2008 |
Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.
Topics: Antipyrine; Charcoal; Clofibric Acid; Diclofenac; Fenoprofen; Gemfibrozil; Halogenation; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Water Pollutants, Chemical; Water Purification; Water Supply | 2008 |
The membrane-activity of Ibuprofen, Diclofenac, and Naproxen: a physico-chemical study with lecithin phospholipids.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry; Calorimetry, Differential Scanning; Diclofenac; Dimyristoylphosphatidylcholine; Fluorescence Resonance Energy Transfer; Ibuprofen; Lecithins; Liposomes; Naproxen; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 2009 |
Glycerolysis of acyl glucuronides as an artifact of in vitro drug metabolism incubations.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Artifacts; Biological Assay; Biotransformation; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Diclofenac; Glucuronates; Glucuronides; Glycerol; Humans; In Vitro Techniques; Mass Spectrometry; Mefenamic Acid; Microsomes, Liver; Naproxen; Propionates; Tolmetin; Uridine Diphosphate Glucuronic Acid | 2009 |
A conditional sequential sampling procedure for drug safety surveillance.
Topics: Aged; Computer Simulation; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Evaluation; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Lactones; Male; Middle Aged; Myocardial Infarction; Naproxen; Product Surveillance, Postmarketing; Risk; Sulfones | 2009 |
Investigating the chlorination of acidic pharmaceuticals and by-product formation aided by an experimental design methodology.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Liquid; Diclofenac; Halogenation; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Molecular Structure; Naproxen; Salicylic Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Water Pollutants, Chemical; Water Supply | 2010 |
Degradation and adsorption of selected pharmaceuticals and personal care products (PPCPs) in agricultural soils.
Topics: Adsorption; Benzhydryl Compounds; Biodegradation, Environmental; Clofibric Acid; Diclofenac; Household Products; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenols; Soil; Soil Microbiology; Soil Pollutants; Triclosan | 2009 |
Cardiovascular risks of nonsteroidal antiinflammatory drugs in patients after hospitalization for serious coronary heart disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cohort Studies; Coronary Artery Disease; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Follow-Up Studies; Hospitalization; Humans; Ibuprofen; Incidence; Lactones; Male; Middle Aged; Myocardial Infarction; Naproxen; Outpatients; Pyrazoles; Retrospective Studies; Risk Factors; Stroke; Sulfonamides; Sulfones; Tennessee | 2009 |
Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDS in the treatment of ankylosing spondylitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bayes Theorem; Celecoxib; Cost-Benefit Analysis; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Costs; Drug-Related Side Effects and Adverse Reactions; Etoricoxib; Humans; Markov Chains; Meta-Analysis as Topic; Models, Economic; Naproxen; Pyrazoles; Pyridines; Quality-Adjusted Life Years; Severity of Illness Index; Spondylitis, Ankylosing; Sulfonamides; Sulfones; Treatment Outcome; United Kingdom | 2010 |
Second interlaboratory exercise on non-steroidal anti-inflammatory drug analysis in environmental aqueous samples.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry Techniques, Analytical; Diclofenac; Environmental Monitoring; Filtration; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Naproxen; Reproducibility of Results; Water Pollutants, Chemical; Water Purification | 2010 |
The role of the acquisition methods in the analysis of the non-steroidal anti-inflammatory drugs in Danube River by gas chromatography-mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Limit of Detection; Naproxen; Rivers; Water Pollutants, Chemical | 2010 |
Electrokinetic supercharging focusing in capillary zone electrophoresis of weakly ionizable analytes in environmental and biological samples.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrophoresis, Capillary; Fenoprofen; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Ketoprofen; Methanol; Naproxen; Piroxicam; Reproducibility of Results; Rivers; Sensitivity and Specificity; Sodium Chloride; Time Factors; Water Pollutants, Chemical | 2010 |
Determination of non-steroidal anti-inflammatory drugs in sewage sludge by direct hollow fiber supported liquid membrane extraction and liquid chromatography-mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Fractionation; Chromatography, Liquid; Diclofenac; Ibuprofen; Ketoprofen; Mass Spectrometry; Naproxen; Reproducibility of Results; Sewage | 2010 |
Capacity of a horizontal subsurface flow constructed wetland system for the removal of emerging pollutants: an injection experiment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Environmental Restoration and Remediation; Ibuprofen; Naproxen; Perfume; Tetrahydronaphthalenes; Waste Disposal, Fluid; Water Movements; Water Pollutants, Chemical; Wetlands | 2010 |
Interaction of copper(II) with the non-steroidal anti-inflammatory drugs naproxen and diclofenac: synthesis, structure, DNA- and albumin-binding.
Topics: Albumins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cations, Divalent; Cattle; Copper; Crystallography, X-Ray; Diclofenac; DNA; Ethidium; Humans; Naproxen; Organometallic Compounds; Serum Albumin; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet | 2011 |
Microbial transformation of pharmaceuticals naproxen, bisoprolol, and diclofenac in aerobic and anaerobic environments.
Topics: Aerobiosis; Anaerobiosis; Biodegradation, Environmental; Bioreactors; Bisoprolol; Diclofenac; Environmental Monitoring; Methane; Naproxen; Oxygen Consumption; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2011 |
Sorption and degradation of wastewater-associated non-steroidal anti-inflammatory drugs and antibiotics in soils.
Topics: Adsorption; Aerobiosis; Agricultural Irrigation; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Biodegradation, Environmental; Diclofenac; Ibuprofen; Naproxen; Soil; Soil Microbiology; Sulfamethoxazole; Trimethoprim; Water Pollutants, Chemical | 2011 |
Uptake from water, biotransformation, and biliary excretion of pharmaceuticals by rainbow trout.
Topics: Animals; Bile; Biotransformation; Bisoprolol; Carbamazepine; Diclofenac; Fresh Water; Ibuprofen; Naproxen; Oncorhynchus mykiss; Pharmaceutical Preparations; Water Pollutants, Chemical | 2011 |
Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: a nationwide cohort study.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Comorbidity; Contraindications; Cyclooxygenase 2 Inhibitors; Denmark; Diclofenac; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Myocardial Infarction; Naproxen; Prognosis; Proportional Hazards Models; Recurrence; Registries; Risk Factors | 2011 |
Harmful effects of NSAIDs among patients with hypertension and coronary artery disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Celecoxib; Confounding Factors, Epidemiologic; Coronary Artery Disease; Diclofenac; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Ibuprofen; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Myocardial Infarction; Naproxen; Odds Ratio; Proportional Hazards Models; Pyrazoles; Randomized Controlled Trials as Topic; Stroke; Sulfonamides; Verapamil | 2011 |
Nonsteroidal anti-inflammatory drugs-induced generalized fixed drug eruption: two cases.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Eruptions; Humans; Male; Middle Aged; Naproxen | 2012 |
Biotransformation of three pharmaceutical active compounds by the fungus Phanerochaete chrysosporium in a fed batch stirred reactor under air and oxygen supply.
Topics: Air; Anti-Inflammatory Agents; Batch Cell Culture Techniques; Biodegradation, Environmental; Bioreactors; Biotransformation; Diclofenac; Ibuprofen; Kinetics; Naproxen; Oxidation-Reduction; Oxygen; Phanerochaete; Water Pollutants, Chemical | 2012 |
Risk of ST versus non-ST elevation myocardial infarction associated with non-steroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Diclofenac; Drug Therapy, Combination; Electrocardiography; Female; France; Heart Conduction System; Humans; Logistic Models; Male; Middle Aged; Myocardial Infarction; Naproxen; Odds Ratio; Risk Assessment; Risk Factors; Treatment Outcome | 2011 |
Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish.
Topics: Animals; Atrazine; Benzhydryl Compounds; Carbamazepine; Diclofenac; Environmental Monitoring; Fishes; Fluoxetine; Gemfibrozil; Ibuprofen; Naproxen; Phenols; Solid Phase Extraction; Solid Phase Microextraction; Waste Disposal, Fluid; Water Pollutants, Chemical | 2011 |
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts | 2012 |
Emerging pollutants in sewage, surface and drinking water in Galicia (NW Spain).
Topics: Atenolol; Benzophenones; Diclofenac; Drinking Water; Environmental Monitoring; Flame Retardants; Ibuprofen; Insecticides; Naproxen; Organophosphates; Plasticizers; Salicylic Acid; Seasons; Sewage; Spain; Sunscreening Agents; Triclosan; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Pollution, Chemical | 2012 |
Biofilm controlled sorption of selected acidic drugs on river sediments characterized by different organic carbon content.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biofilms; Carbon; Diclofenac; Gas Chromatography-Mass Spectrometry; Geologic Sediments; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Naproxen; Rivers; Water Pollutants, Chemical | 2012 |
Determination of non-steroidal anti-inflammatory drugs in water samples by solid-phase microextraction based sol-gel technique using poly(ethylene glycol) grafted multi-walled carbon nanotubes coated fiber.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Diclofenac; Gels; Hydrogen-Ion Concentration; Ibuprofen; Nanotubes, Carbon; Naproxen; Polyethylene Glycols; Salts; Solid Phase Microextraction; Temperature; Time Factors; Water Pollutants, Chemical | 2012 |
Intramuscular ketorolac inhibits activation of rat peripheral NMDA receptors.
Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dinoprostone; Excitatory Amino Acid Agonists; Female; Injections, Intramuscular; Ketorolac; Male; Naproxen; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Trigeminal Nerve | 2012 |
Bioavailability of pharmaceuticals in waters close to wastewater treatment plants: use of fish bile for exposure assessment.
Topics: Animals; Anti-Inflammatory Agents; Bile; Biological Availability; Carbamazepine; Chromatography, Liquid; Citalopram; Cyclohexanols; Diclofenac; Finland; Ibuprofen; Liver; Male; Naproxen; Oncorhynchus mykiss; Plasma; Venlafaxine Hydrochloride; Wastewater; Water Pollutants, Chemical | 2012 |
Rejection of pharmaceuticals by forward osmosis membranes.
Topics: Carbamazepine; Diclofenac; Filtration; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Membranes, Artificial; Naproxen; Osmosis; Pharmaceutical Preparations; Water Pollutants, Chemical; Water Purification | 2012 |
Acidic pharmaceuticals in domestic wastewater and receiving water from hyper-urbanization city of China (Shanghai): environmental release and ecological risk.
Topics: China; Cities; Diclofenac; Environmental Monitoring; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Urbanization; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Pollution, Chemical | 2013 |
Pre-concentration of non-steroidal anti-inflammatory drugs in water using dispersive liquid-liquid and single-drop microextraction with high-performance liquid chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Ibuprofen; Liquid Phase Microextraction; Naproxen; Water Pollutants, Chemical | 2012 |
Use of nonsteroidal anti-inflammatory drugs among healthy people and specific cerebrovascular safety.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Cohort Studies; Denmark; Diclofenac; Humans; Ibuprofen; Intracranial Hemorrhages; Naproxen; Odds Ratio; Proportional Hazards Models; Risk; Stroke | 2014 |
Determination of non-steroidal anti-inflammatory drugs in urine by hollow-fiber liquid membrane-protected solid-phase microextraction based on sol-gel fiber coating.
Topics: 1-Octanol; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Diclofenac; Drug Stability; Humans; Ibuprofen; Limit of Detection; Linear Models; Nanotubes, Carbon; Naproxen; Phase Transition; Porosity; Reproducibility of Results; Sodium Chloride; Solid Phase Microextraction; Temperature | 2012 |
The anti-inflammatory drugs diclofenac, naproxen and ibuprofen are found in the bile of wild fish caught downstream of a wastewater treatment plant.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Cyprinidae; Diclofenac; Environmental Monitoring; Female; Ibuprofen; Lakes; Male; Naproxen; Waste Disposal, Fluid; Water Pollutants, Chemical | 2013 |
Multi-phase partitioning, ecological risk and fate of acidic pharmaceuticals in a wastewater receiving river: the role of colloids.
Topics: Aquatic Organisms; Clofibric Acid; Colloids; Diclofenac; Ecotoxicology; Geologic Sediments; Ibuprofen; Ketoprofen; Models, Theoretical; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Wastewater; Water Pollutants, Chemical | 2013 |
Diclofenac causes more leakage than naproxen in anastomoses in the small intestine of the rat.
Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Body Weight; Diclofenac; Hydroxyproline; Ileum; Intestine, Small; Male; Naproxen; Pressure; Rats; Rats, Wistar; Wounds and Injuries | 2013 |
How safe is Celecoxib for Asian-Indian patients with rheumatic diseases?
Topics: Adult; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Drug Substitution; Female; Humans; Hypertension; India; Indomethacin; Male; Naproxen; Pyrazoles; Retrospective Studies; Rheumatic Diseases; Sulfonamides; Tertiary Care Centers | 2013 |
Physicians should be cautious when prescribing diclofenac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Diclofenac; Drug and Narcotic Control; Humans; Naproxen; Risk Factors | 2013 |
Effects of ibuprofen, diclofenac, naproxen, and piroxicam on the course of pregnancy and pregnancy outcome: a prospective cohort study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Diclofenac; Female; Humans; Ibuprofen; Infant, Low Birth Weight; Infant, Newborn; Naproxen; Norway; Piroxicam; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Risk; Young Adult | 2013 |
[Occurrence and risk assessment of five selected PPCPs in municipal wastewater treatment plant and the receiving water].
Topics: China; Cities; Clofibric Acid; Diclofenac; Environmental Monitoring; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2013 |
Non-steroidal anti-inflammatory drugs in Indian rivers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; India; Ketoprofen; Naproxen; Rivers; Sewage; Solid Phase Extraction; Water Pollutants, Chemical | 2014 |
More pain for painkillers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Naproxen; Pain; Pyrazoles; Risk Factors; Safety-Based Drug Withdrawals; Sulfonamides; United States; United States Food and Drug Administration | 2013 |
Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Ibuprofen; Naproxen; Piroxicam; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 2014 |
Genotoxic response and oxidative stress induced by diclofenac, ibuprofen and naproxen in Daphnia magna.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Daphnia; Diclofenac; DNA Damage; Ibuprofen; Lipid Peroxidation; Mexico; Mutagenicity Tests; Naproxen; No-Observed-Adverse-Effect Level; Oxidative Stress; Protein Carbonylation; Superoxide Dismutase; Time Factors; Toxicity Tests, Acute; Water Pollutants, Chemical | 2014 |
Adsorption characteristics of selected hydrophilic and hydrophobic micropollutants in water using activated carbon.
Topics: 2,4-Dichlorophenoxyacetic Acid; Acetaminophen; Adsorption; Atrazine; Caffeine; Carbanilides; Carbon; Diclofenac; Endocrine Disruptors; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Naproxen; Pesticides; Pharmaceutical Preparations; Sulfamethazine; Sulfamethoxazole; Temperature; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2014 |
Cardiovascular safety of NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Ibuprofen; Naproxen | 2014 |
Removal of acidic pharmaceuticals within a nitrifying recirculating biofilter.
Topics: Adsorption; Bacteria; Biofilms; Diclofenac; DNA, Bacterial; Filtration; Gemfibrozil; Genes, Bacterial; Ibuprofen; Naproxen; Nitrification; Waste Disposal, Fluid; Water Pollutants, Chemical | 2014 |
Concentration of non-steroidal anti-inflammatory drugs in the pelvic floor muscles: an experimental comparative rat model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Chronic Pain; Diclofenac; Female; Meloxicam; Muscles; Nabumetone; Naproxen; Pelvic Floor; Pelvic Pain; Piroxicam; Rats; Rats, Wistar; Thiazines; Thiazoles | 2014 |
[Simultaneous determination of nine pharmaceuticals personal care products in waters by solid phase extraction-gas chromatography-mass spectrometry].
Topics: Acetaminophen; Agricultural Irrigation; Benzhydryl Compounds; Clofibric Acid; Diclofenac; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Naproxen; Phenols; Salicylic Acid; Solid Phase Extraction; Triclosan; Water; Water Pollutants, Chemical | 2014 |
Transformation and removal pathways of four common PPCP/EDCs in soil.
Topics: Benzhydryl Compounds; Diclofenac; Endocrine Disruptors; Environmental Monitoring; Environmental Restoration and Remediation; Naproxen; Phenols; Soil; Soil Pollutants | 2014 |
Binary mixtures of diclofenac with paracetamol, ibuprofen, naproxen, and acetylsalicylic acid and these pharmaceuticals in isolated form induce oxidative stress on Hyalella azteca.
Topics: Acetaminophen; Amphipoda; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Catalase; Diclofenac; Glutathione Peroxidase; Ibuprofen; Lipid Peroxidation; Naproxen; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Superoxide Dismutase; Water Pollutants, Chemical | 2014 |
Precision cut intestinal slices are an appropriate ex vivo model to study NSAID-induced intestinal toxicity in rats.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caspase 9; Cell Survival; Diclofenac; Diflunisal; Endoplasmic Reticulum Stress; Gene Expression; Glutathione; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Indomethacin; Jejunum; Male; Naproxen; Rats, Wistar; Tissue Culture Techniques | 2014 |
[Interaction between NSAIDs and acetylsalicylic acid disregarded].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Interactions; Humans; Naproxen; Thrombosis | 2014 |
Occurrence of selected pharmaceuticals in the principal sewage treatment plants in Rome (Italy) and in the receiving surface waters.
Topics: Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Estrone; Gemfibrozil; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Rome; Seasons; Solid Phase Extraction; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
Ion-exchange selectivity of diclofenac, ibuprofen, ketoprofen, and naproxen in ureolyzed human urine.
Topics: Acetaminophen; Anion Exchange Resins; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Diclofenac; Humans; Hydrogen Bonding; Ibuprofen; Ion Exchange; Ketoprofen; Kinetics; Molecular Structure; Naproxen; Static Electricity; Urea; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
Effect of temperature on removal of trace organic chemicals in managed aquifer recharge systems.
Topics: Benzophenones; Diclofenac; Gemfibrozil; Groundwater; Ketoprofen; Naproxen; Soil Microbiology; Temperature; Trimethoprim; Water Pollutants, Chemical | 2015 |
Tunable thermo-responsive hydrogels: synthesis, structural analysis and drug release studies.
Topics: Acrylamides; Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Hot Temperature; Hydrogels; Naproxen; Ultraviolet Rays | 2015 |
A miniaturized in vitro release method for investigating drug-release mechanisms.
Topics: Carbamazepine; Computer Simulation; Diclofenac; Drug Delivery Systems; Drug Liberation; Humans; Intestinal Absorption; Metoprolol; Miniaturization; Models, Theoretical; Naproxen | 2015 |
NSAIDs and spontaneous abortions - true effect or an indication bias?
Topics: Abortion, Spontaneous; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Israel; Middle Aged; Naproxen; Pregnancy; Retrospective Studies; Time Factors; Young Adult | 2015 |
Design, synthesis and QSAR studies on a series of 2, 5-disubstituted- 1,3,4-oxadiazole derivatives of diclofenac and naproxen for analgesic and anti-inflammatory activity.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Design; Female; Inflammation; Male; Mice; Molecular Structure; Naproxen; Oxadiazoles; Pain; Pain Measurement; Quantitative Structure-Activity Relationship; Rats | 2015 |
Thermodynamic insights into drug-surfactant interactions: Study of the interactions of naporxen, diclofenac sodium, neomycin, and lincomycin with hexadecytrimethylammonium bromide by using isothermal titration calorimetry.
Topics: Calorimetry; Cetrimonium; Cetrimonium Compounds; Diclofenac; Lincomycin; Micelles; Naproxen; Neomycin; Pharmaceutical Preparations; Surface-Active Agents; Thermodynamics | 2015 |
Nonsteroidal anti-inflammatory drugs in-vitro and in-vivo treatment and Multidrug Resistance Protein 4 expression in human platelets.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Case-Control Studies; Celecoxib; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Megakaryocytes; Middle Aged; Multidrug Resistance-Associated Proteins; Naproxen; Osteoarthritis; Platelet Activation; Platelet Aggregation; RNA, Messenger | 2016 |
Drug Oxidation by Cytochrome P450BM3 : Metabolite Synthesis and Discovering New P450 Reaction Types.
Topics: Catalysis; Chlorzoxazone; Cytochrome P-450 Enzyme System; Diclofenac; Humans; Hydrogen Bonding; Kinetics; Naproxen; Oxidation-Reduction; Protein Engineering; Testosterone | 2015 |
TiO2 photocatalysis of naproxen: effect of the water matrix, anions and diclofenac on degradation rates.
Topics: Catalysis; Chromatography, Liquid; Diclofenac; Kinetics; Naproxen; Photochemical Processes; Titanium; Water; Water Pollutants, Chemical | 2015 |
Prevalence, trends, patterns and associations of analgesic use in Germany.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Analgesics; Aspirin; Diclofenac; Drug Therapy; Female; Germany; Health Surveys; Humans; Ibuprofen; Logistic Models; Male; Middle Aged; Multivariate Analysis; Naproxen; Nonprescription Drugs; Pain; Prevalence; Sex Factors; Social Class; Young Adult | 2015 |
Single-drop microextraction combined in-line with capillary electrophoresis for the determination of nonsteroidal anti-inflammatory drugs in urine samples.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrophoresis, Capillary; Equipment Design; Humans; Ibuprofen; Ketoprofen; Limit of Detection; Liquid Phase Microextraction; Naproxen; Urinalysis | 2016 |
Occurrence of non-steroidal anti-inflammatory drugs in Tehran source water, municipal and hospital wastewaters, and their ecotoxicological risk assessment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Liquid; Diclofenac; Ecotoxicology; Environmental Monitoring; Hospitals; Ibuprofen; Iran; Mass Spectrometry; Naproxen; Risk Assessment; Rivers; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2015 |
In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and COX-2 inhibition.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; HEK293 Cells; Humans; Male; Middle Aged; Naphthalenes; Naproxen; Propionates; Receptors, Thromboxane; Young Adult | 2016 |
Graphene oxide-based dispersive solid-phase extraction combined with in situ derivatization and gas chromatography-mass spectrometry for the determination of acidic pharmaceuticals in water.
Topics: Diclofenac; Gas Chromatography-Mass Spectrometry; Graphite; Ibuprofen; Ketoprofen; Naproxen; Osmolar Concentration; Pharmaceutical Preparations; Solid Phase Extraction; Solvents; Water; Water Pollutants, Chemical | 2015 |
The Influence of Efflux Pump Inhibitors on the Activity of Non-Antibiotic NSAIDS against Gram-Negative Rods.
Topics: Acetaminophen; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Escherichia coli; Gram-Negative Bacteria; Ibuprofen; Mefenamic Acid; Microbial Sensitivity Tests; Naproxen | 2016 |
Evidence that diclofenac and celecoxib are thyroid hormone receptor beta antagonists.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Computer Simulation; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Male; Mesenteric Arteries; Models, Molecular; Naproxen; Rats; Rats, Wistar; Thyroid Hormone Receptors beta; Triiodothyronine; Vasodilation | 2016 |
Introduction of high nitrogen doped graphene as a new cationic carrier in electromembrane extraction.
Topics: Cations; Diclofenac; Electrochemical Techniques; Graphite; Membranes, Artificial; Models, Chemical; Naproxen; Nitrogen | 2016 |
Sorption of diclofenac and naproxen onto MWCNT in model wastewater treated by H2O2 and/or UV.
Topics: Adsorption; Diclofenac; Hydrogen Peroxide; Kinetics; Models, Chemical; Nanotubes, Carbon; Naproxen; Ultraviolet Rays; Waste Disposal, Fluid; Wastewater | 2016 |
NSAIDs and serious cardiovascular disorders: especially cox-2 inhibitors and diclofenac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Ibuprofen; Naproxen | 2016 |
Use of non-steroidal anti-inflammatory drugs correlates with the risk of venous thromboembolism in knee osteoarthritis patients: a UK population-based case-control study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Lactones; Logistic Models; Male; Meloxicam; Middle Aged; Naproxen; Odds Ratio; Osteoarthritis, Knee; Risk Factors; Sulfones; Thiazines; Thiazoles; Treatment Outcome; United Kingdom; Venous Thromboembolism | 2016 |
Common pain relievers may increase heart problems. High-dosage ibuprofen and diclofenac linked to elevated risk of death; naproxen, acetaminophen offer alternatives.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Naproxen; Pain | 2010 |
[Paracetamol in knee and hip arthrosis is dispensable].
Topics: Acetaminophen; Diclofenac; Etoricoxib; Humans; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Pyridines; Sulfones; Treatment Outcome | 2016 |
Solar photolysis versus TiO2-mediated solar photocatalysis: a kinetic study of the degradation of naproxen and diclofenac in various water matrices.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Chromatography, Liquid; Diclofenac; Kinetics; Mass Spectrometry; Naproxen; Photolysis; Sunlight; Titanium; Water; Water Pollutants, Chemical | 2016 |
Suitability of passive sampling for the monitoring of pharmaceuticals in Finnish surface waters.
Topics: Calibration; Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Finland; Ibuprofen; Ketoprofen; Lakes; Naproxen; Pharmaceutical Preparations; Rivers; Seasons; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2016 |
Determination of ibuprofen, naproxen and diclofenac in aqueous samples using a multi-template molecularly imprinted polymer as selective adsorbent for solid-phase extraction.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Drug Residues; Ibuprofen; Indicators and Reagents; Molecular Imprinting; Naproxen; Pharmaceutical Solutions; Polymers; Reproducibility of Results; Rivers; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2016 |
Biophysical study of the non-steroidal anti-inflammatory drugs (NSAID) ibuprofen, naproxen and diclofenac with phosphatidylserine bilayer membranes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Lipid Bilayers; Naproxen; Phosphatidylserines | 2016 |
The fate of selected pharmaceuticals in solar stills: Transfer, thermal degradation or photolysis?
Topics: Ampicillin; Carbamazepine; Diclofenac; Drug Residues; Ibuprofen; Naproxen; Photolysis; Sunlight; Water Pollutants, Chemical | 2017 |
Assessing the phototransformation of diclofenac, clofibric acid and naproxen in surface waters: Model predictions and comparison with field data.
Topics: Clofibric Acid; Diclofenac; Kinetics; Models, Chemical; Naproxen; Photolysis; Water Pollutants, Chemical | 2016 |
Central nervous system toxicity of mefenamic acid overdose compared with other NSAIDs: an analysis of cases reported to the United Kingdom National Poisons Information Service.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Diclofenac; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Ibuprofen; Infant; Infant, Newborn; Logistic Models; Male; Mefenamic Acid; Middle Aged; Multivariate Analysis; Naproxen; Neurotoxicity Syndromes; Poison Control Centers; Sex Factors; United Kingdom; Young Adult | 2017 |
Poly(aryleneethynylene) Tongue That Identifies Nonsteroidal Anti-Inflammatory Drugs in Water: A Test Case for Combating Counterfeit Drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Counterfeit Drugs; Diclofenac; Ibuprofen; Naproxen; Water | 2017 |
Non-steroidal anti-inflammatory drugs in the watercourses of Elbe basin in Czech Republic.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Czech Republic; Diclofenac; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Rivers; Water Pollutants, Chemical | 2017 |
Alkylglycerol Derivatives, a New Class of Skin Penetration Modulators.
Topics: Administration, Cutaneous; Animals; Diclofenac; Drug Carriers; Glyceryl Ethers; Glycyrrhizic Acid; Naproxen; Permeability; Piroxicam; Skin; Skin Absorption; Spectroscopy, Fourier Transform Infrared; Swine | 2017 |
Mass spectrometry based in vitro assay investigations on the transformation of pharmaceutical compounds by oxidative enzymes.
Topics: Acetaminophen; Carbamazepine; Diclofenac; Horseradish Peroxidase; Ibuprofen; Laccase; Mass Spectrometry; Naproxen; Oxidation-Reduction; Sotalol; Sulfamethoxazole; Water Pollutants, Chemical; Water Purification | 2017 |
Sorption and desorption of selected non-steroidal anti-inflammatory drugs in an agricultural loam-textured soil.
Topics: Adsorption; Agriculture; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Ketoprofen; Naproxen; Soil; Soil Pollutants | 2017 |
Occurrence of naproxen, ibuprofen, and diclofenac residues in wastewater and river water of KwaZulu-Natal Province in South Africa.
Topics: Chromatography, High Pressure Liquid; Cities; Diclofenac; Dose-Response Relationship, Drug; Environmental Monitoring; Ibuprofen; Naproxen; Rivers; Solid Phase Extraction; South Africa; Wastewater; Water Pollutants, Chemical | 2017 |
NSAIDs relieve osteoarthritis (OA) pain, but cardiovascular safety in question even for diclofenac, ibuprofen, naproxen, and celecoxib: what are the alternatives?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Diclofenac; Humans; Ibuprofen; Naproxen; Network Meta-Analysis; Osteoarthritis; Pain | 2017 |
Establishing Structure Property Relationship in Drug Partitioning into and Release from Niosomes: Physical Chemistry Insights with Anti-Inflammatory Drugs.
Topics: Anti-Inflammatory Agents; Delayed-Action Preparations; Diclofenac; Drug Liberation; Hydrogen-Ion Concentration; Naproxen; Octoxynol; Polidocanol; Polyethylene Glycols; Sodium Dodecyl Sulfate | 2017 |
Penetration and pharmacokinetics of non-steroidal anti-inflammatory drugs in rat prostate tissue.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Celecoxib; Chromatography, Liquid; Comparative Effectiveness Research; Diclofenac; Disease Models, Animal; Ibuprofen; Inflammation; Male; Naproxen; Pelvic Pain; Prostate; Prostatitis; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2018 |
Degradation of anti-inflammatory drugs in municipal wastewater by heterogeneous photocatalysis and electro-Fenton process.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Hydrogen Peroxide; Ibuprofen; Naproxen; Wastewater; Water Pollutants, Chemical | 2019 |
Comparative cardiovascular safety of nonsteroidal anti-inflammatory drugs in patients with hypertension: a population-based cohort study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular System; Celecoxib; Cyclooxygenase 2 Inhibitors; Databases, Pharmaceutical; Diclofenac; Female; Hospitalization; Humans; Hypertension; Ibuprofen; Male; Mefenamic Acid; Middle Aged; Naproxen; Risk Factors | 2018 |
Pharmaceutical grey water footprint: Accounting, influence of wastewater treatment plants and implications of the reuse.
Topics: Agricultural Irrigation; Carbamazepine; Diclofenac; Naproxen; Nitrates; Pharmaceutical Preparations; Phosphates; Recycling; Spain; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2018 |
Population scale retrospective analysis reveals distinctive antidepressant and anxiolytic effects of diclofenac, ketoprofen and naproxen in patients with pain.
Topics: Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Anxiety; Cohort Studies; Depression; Diclofenac; Humans; Ketoprofen; Naproxen; Pain | 2018 |
Risk of myocardial infarction with use of selected non-steroidal anti-inflammatory drugs in patients with spondyloarthritis and osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Diclofenac; Female; Humans; Male; Middle Aged; Myocardial Infarction; Naproxen; Osteoarthritis; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Spondylarthritis; Young Adult | 2018 |
Transformation, CO
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Biofilms; Carbon Dioxide; Deltaproteobacteria; Diclofenac; Firmicutes; Gammaproteobacteria; Ibuprofen; In Situ Hybridization, Fluorescence; Naproxen; RNA, Ribosomal, 16S; Waste Disposal, Fluid; Wastewater; Water Microbiology; Water Pollutants, Chemical | 2018 |
Diclofenac use and cardiovascular risks: series of nationwide cohort studies.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cohort Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Propensity Score; Risk Factors | 2018 |
Comparative study of the toxicity between three non-steroidal anti-inflammatory drugs and their UV/Na
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carps; Diclofenac; Ecological Parameter Monitoring; Environmental Pollutants; Environmental Pollution; Fish Diseases; Ibuprofen; Medical Waste Disposal; Naproxen; Oxidation-Reduction; Photolysis; Sodium Compounds; Sulfates; Toxicity Tests, Acute; Ultraviolet Rays; Wastewater; Water Purification | 2018 |
A new laccase-mediator system facing the biodegradation challenge: Insight into the NSAIDs removal.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biodegradation, Environmental; Diclofenac; Hydroxylation; Ketoprofen; Laccase; Naproxen; Trametes | 2019 |
Environmentally-relevant mixture of pharmaceutical drugs stimulates sex-steroid hormone production and modulates the expression of candidate genes in the ovary of juvenile female rainbow trout.
Topics: Acetaminophen; Animals; Belgium; Carbamazepine; Diclofenac; Endocrine Disruptors; Female; Gene Expression Regulation; Gonadal Steroid Hormones; Irbesartan; Naproxen; Oncorhynchus mykiss; Ovary; Testosterone; Water Pollutants, Chemical | 2018 |
MI risk associated with naproxen and diclofenac in spondyloarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Naproxen; Spondylarthritis | 2019 |
C18-Coated Solid-Phase Microextraction Fibers for the Quantification of Partitioning of Organic Acids to Proteins, Lipids, and Cells.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Cattle; Cells, Cultured; Diclofenac; Genistein; HEK293 Cells; Humans; Ibuprofen; Kinetics; Liposomes; Naproxen; Phospholipids; Serum Albumin, Bovine; Solid Phase Microextraction; Torsemide; Warfarin | 2019 |
Effectiveness of an academic detailing intervention in primary care on the prescribing of non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Prescriptions; Drug Utilization; Education, Medical, Continuing; General Practice; General Practitioners; Humans; Naproxen; Norway; Practice Patterns, Physicians'; Prescription Drugs; Primary Health Care | 2019 |
Mechanisms and quantification of adsorption of three anti-inflammatory pharmaceuticals onto goethite with/without surface-bound organic acids.
Topics: Acids; Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Iron Compounds; Ketoprofen; Minerals; Naproxen; Osmolar Concentration | 2019 |
Nickel-iron layered double hydroxide nanostructures for micro solid phase extraction of nonsteroidal anti-inflammatory drugs, followed by quantitation by HPLC-UV.
Topics: Adsorption; Alloys; Anti-Inflammatory Agents, Non-Steroidal; Biosensing Techniques; Chromatography, High Pressure Liquid; Diclofenac; Humans; Hydroxides; Ibuprofen; Iron; Limit of Detection; Mefenamic Acid; Metal Nanoparticles; Naproxen; Nickel; Reproducibility of Results; Solid Phase Microextraction; Surface Properties | 2019 |
Evaluation of the photosynthetic parameters, emission of volatile organic compounds and ultrastructure of common green leafy vegetables after exposure to non-steroidal anti-inflammatory drugs (NSAIDs).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Atriplex; Diclofenac; Environmental Pollutants; Ibuprofen; Lactuca; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Naproxen; Photosynthesis; Plant Leaves; Spinacia oleracea; Volatile Organic Compounds | 2019 |
Oxyfunctionalization of nonsteroidal anti-inflammatory drugs by filamentous-fungi.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Basidiomycota; Cytochrome P-450 Enzyme System; Diclofenac; Fungi; Ibuprofen; Mefenamic Acid; Mucor; Naproxen; Proteomics | 2019 |
Bioremoval of non-steroidal anti-inflammatory drugs by Pseudoxanthomonas sp. DIN-3 isolated from biological activated carbon process.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Charcoal; Diclofenac; Ecosystem; Ibuprofen; Naproxen | 2019 |
A nanohybrid composed of polyoxotungstate and graphene oxide for dispersive micro solid-phase extraction of non-steroidal anti-inflammatory drugs prior to their quantitation by HPLC.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Graphite; Ibuprofen; Limit of Detection; Nanostructures; Naproxen; Polymers; Porosity; Solid Phase Extraction; Spectrophotometry, Ultraviolet; Tungsten Compounds; Water Pollutants, Chemical | 2019 |
Mitochondrial Permeability Transition Pore Sealing Agents and Antioxidants Protect Oxidative Stress and Mitochondrial Dysfunction Induced by Naproxen, Diclofenac and Celecoxib.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Celecoxib; Diclofenac; Glutathione; Lipid Peroxidation; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocytes, Cardiac; Naproxen; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Reactive Oxygen Species | 2019 |
Robust biodegradation of naproxen and diclofenac by laccase immobilized using electrospun nanofibers with enhanced stability and reusability.
Topics: Animals; Artemia; Biocatalysis; Biodegradation, Environmental; Diclofenac; Enzyme Stability; Enzymes, Immobilized; Equipment Reuse; Hydrogen-Ion Concentration; Laccase; Nanofibers; Naproxen; Polyesters; Temperature; Water Pollutants, Chemical | 2019 |
Combustion fabrication of magnetic porous carbon as a novel magnetic solid-phase extraction adsorbent for the determination of non-steroidal anti-inflammatory drugs.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Carbon; Diclofenac; Green Chemistry Technology; Ketoprofen; Limit of Detection; Magnetite Nanoparticles; Naproxen; Porosity; Rivers; Solid Phase Extraction; Water Pollutants, Chemical | 2019 |
Association of tramadol with risk of myocardial infarction among patients with osteoarthritis.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Diclofenac; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Naproxen; Osteoarthritis; Propensity Score; Proportional Hazards Models; Risk Factors; Tramadol | 2020 |
Formation of Drug-Participating Catanionic Aggregates for Extended Delivery of Non-Steroidal Anti-Inflammatory Drugs from Contact Lenses.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cations; Contact Lenses; Diclofenac; Diffusion; Drug Delivery Systems; Drug Liberation; Fatty Alcohols; Flurbiprofen; Hydrophobic and Hydrophilic Interactions; Kinetics; Naproxen; Quaternary Ammonium Compounds; Surface-Active Agents; Viscosity | 2019 |
Monitoring the release of anti-inflammatory and analgesic pharmaceuticals in the receiving environment.
Topics: Analgesics; Anti-Inflammatory Agents; Diclofenac; Environmental Monitoring; Hospitals; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Seasons; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2019 |
Electrospun NiFe layered double hydroxide/Nylon 6 composite nanofibers as a sorbent for micro solid phase extraction by packed sorbent of non-steroidal anti-inflammatory drugs in human blood.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Caprolactam; Chromatography, High Pressure Liquid; Diclofenac; Humans; Hydroxides; Iron; Limit of Detection; Mefenamic Acid; Nanofibers; Naproxen; Nickel; Polymers; Solid Phase Microextraction | 2020 |
Effects of chronic exposure to a pharmaceutical mixture on the three-spined stickleback (gasterosteus aculeatus) population dynamics in lotic mesocosms.
Topics: Acetaminophen; Animals; Belgium; Carbamazepine; Diclofenac; Female; Models, Theoretical; Naproxen; Pharmaceutical Preparations; Population Dynamics; Rivers; Smegmamorpha; Water Pollutants, Chemical | 2020 |
Diet quality and NSAIDs promote changes in formation of prostaglandins by an aquatic invertebrate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Diclofenac; Diet; Ibuprofen; Invertebrates; Ketoprofen; Lipid Metabolism; Naproxen; Prostaglandins | 2020 |
Predicted values for human total clearance of a variety of typical compounds with differently humanized-liver mouse plasma data.
Topics: Acetamides; Albuterol; Animals; Carbamates; Chromatography, Liquid; Diazepam; Diclofenac; Digitoxin; Humans; Itraconazole; Ketoprofen; Liver; Metabolic Clearance Rate; Mice; Mice, Transgenic; Naproxen; Pharmaceutical Preparations; Phenytoin; Piperidines; Pravastatin; Pyrimidines; Quinidine; Tandem Mass Spectrometry; Telmisartan; Terfenadine; Verapamil | 2020 |
Naproxen affects multiple organs in fish but is still an environmentally better alternative to diclofenac.
Topics: Animals; Bioaccumulation; Diclofenac; Dose-Response Relationship, Drug; Gene Expression; Humans; Kidney; Liver; Male; Models, Theoretical; Naproxen; Smegmamorpha; Sweden; Water Pollutants, Chemical | 2020 |
Rational use of drugs as a source control measure to fight drug pollution.
Topics: Diclofenac; Naproxen; Pharmaceutical Preparations; Wastewater | 2021 |
Solidified floating organic drop microextraction (SFODME) for the simultaneous analysis of three non-steroidal anti-inflammatory drugs in aqueous samples by HPLC.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Organic; Chromatography, High Pressure Liquid; Diclofenac; Dodecanol; Hydrogen-Ion Concentration; Ions; Limit of Detection; Linear Models; Liquid Phase Microextraction; Mefenamic Acid; Methanol; Naproxen; Osmolar Concentration; Pharmaceutical Preparations; Reproducibility of Results; Seawater; Solvents; Temperature; Water; Water Pollutants, Chemical | 2021 |
Deterministic and probabilistic health risk assessment for exposure to non-steroidal anti-inflammatory drugs in an Indian river.
Topics: Adolescent; Animals; Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; Diclofenac; Humans; Infant; Infant, Newborn; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers | 2021 |
Integrated multi-biomarker responses of juvenile rainbow trout (Oncorhynchus mykiss) to an environmentally relevant pharmaceutical mixture.
Topics: Acetaminophen; Animals; Belgium; Biomarkers; Brain; Carbamazepine; Diclofenac; Irbesartan; Liver; Lysosomes; Naproxen; Neurotoxicity Syndromes; Oncorhynchus mykiss; Rivers; Serotonin; Water Pollutants, Chemical | 2021 |
Layered terbium hydroxides for simultaneous drug delivery and imaging.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Cell Survival; Diclofenac; Drug Delivery Systems; Drug Liberation; Drug Stability; Erythrocytes; Female; HEK293 Cells; Hemolysis; Humans; Hydroxides; Ibuprofen; Ion Exchange; Naproxen; Optical Imaging; Rats, Wistar; Terbium | 2021 |
HSA nanoparticles in drug recognition: mechanistic insights with naproxen, diclofenac and methimazole.
Topics: Diclofenac; Drug Carriers; Humans; Methimazole; Nanoparticles; Naproxen | 2022 |
The occurrence of non-steroidal anti-inflammatory drugs (NSAIDs) in Malaysian urban domestic wastewater.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Naproxen; Pharmaceutical Preparations; Wastewater; Water Pollutants, Chemical | 2022 |
Effect of diclofenac and naproxen and their mixture on spring barley seedlings and Heterocypris incongruens.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carotenoids; Chlorophyll; Crustacea; Diclofenac; Drug Interactions; Hordeum; Hydrogen Peroxide; Malondialdehyde; Naproxen; Oxidoreductases; Plant Proteins; Proline; Seedlings | 2021 |
New look at the metabolism of nonsteroidal anti-inflammatory drugs: influence on human serum albumin antioxidant activity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Binding Sites; Diclofenac; Humans; Ketoprofen; Naproxen; Serum Albumin; Serum Albumin, Human | 2023 |
Design and application of molecularly imprinted polymers for adsorption and environmental assessment of anti-inflammatory drugs in wastewater samples.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Emulsions; Ibuprofen; Molecular Imprinting; Molecularly Imprinted Polymers; Naproxen; Wastewater | 2022 |
From the pills to environment - Prediction and tracking of non-steroidal anti-inflammatory drug concentrations in wastewater.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Naproxen; Pharmaceutical Preparations; Sewage; Wastewater; Water Pollutants, Chemical | 2022 |
Impact of various aeration strategies on the removal of micropollutants and biological effects in aerated horizontal flow treatment wetlands.
Topics: Biological Oxygen Demand Analysis; Caffeine; Diclofenac; Escherichia coli; Naproxen; Nitrogen; Oxygen; Waste Disposal, Fluid; Wastewater; Wetlands | 2022 |
Association between tramadol use and risk of pneumonia in the middle-aged and elderly populations: a propensity-score matched cohort study.
Topics: Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Codeine; Cohort Studies; Diclofenac; Etoricoxib; Humans; Middle Aged; Naproxen; Pneumonia; Tramadol | 2022 |
The Effects of Ibuprofen, Naproxen and Diclofenac on cell Apoptosis, Cell Proliferation and Histology Changes in Human Cholangiocarcinoma Cell Lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; Diclofenac; Humans; Ibuprofen; Lipids; Naproxen | 2022 |
A comprehensive update on the pharmacological management of heterotopic ossification following hip arthroplasty: a level I evidenced based expert opinion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Celecoxib; Diclofenac; Expert Testimony; Humans; Naproxen; Ossification, Heterotopic; Postoperative Complications | 2022 |
Highly sensitive and simultaneous electrochemical determinations of non-steroidal anti-inflammatory drugs in water using nanostructured carbon-based paste electrodes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrochemical Techniques; Electrodes; Fullerenes; Graphite; Ibuprofen; Nanotubes, Carbon; Naproxen; Reproducibility of Results | 2022 |
Comparative analysis of the use of non-steroidal anti-inflammatory drugs in Montenegro, Finland and Croatia in the period 2010-2019.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Croatia; Diclofenac; Finland; Humans; Montenegro; Naproxen | 2022 |
Medicine-Induced Acute Kidney Injury Findings from Spontaneous Reporting Systems, Sequence Symmetry Analysis and a Case-Control Study with a Focus on Medicines Used in Primary Care.
Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Amlodipine; Amphotericin B; Australia; Case-Control Studies; Ciprofloxacin; Diclofenac; Furosemide; Humans; Ibuprofen; Metformin; Naproxen; Omeprazole; Primary Health Care; Ramipril; Simvastatin; Spironolactone; Sulfamethoxazole; Telmisartan; Trimethoprim; Valacyclovir; Zoledronic Acid | 2022 |
2022 Taiwan Guidelines for Acute Treatment of Migraine.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin Gene-Related Peptide Receptor Antagonists; Child; Diclofenac; Female; Headache; Humans; Ibuprofen; Migraine Disorders; Morphine Derivatives; Naproxen; Nasal Sprays; Pregnancy; Prochlorperazine; Taiwan; Tramadol; Tryptamines | 2022 |
Pharmaceuticals, natural and synthetic hormones and phenols in sediments from an eutrophic estuary, Jurujuba Sound, Guanabara Bay, Brazil.
Topics: Bays; Brazil; Diclofenac; Endocrine Disruptors; Environmental Monitoring; Estradiol; Estriol; Estrogens; Estrone; Estuaries; Gemfibrozil; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenols; Water Pollutants, Chemical | 2022 |
Preclinical comparison of antinociceptive effects between ibuprofen, diclofenac, naproxen, and acetaminophen on acid-stimulated body stretching and acid-depressed feeding behaviors in rats.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Feeding Behavior; Ibuprofen; Lactic Acid; Male; Naproxen; Pain; Rats | 2022 |
Gestational NSAIDs distinctly reprogram cardiac injury in preeclamptic rats: Roles of cyclooxygenase, apoptotic and autophagic trails.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Naproxen; Placenta; Pre-Eclampsia; Pregnancy; Rats | 2022 |
Removal of Non-Steroidal Anti-Inflammatory Drugs from Drinking Water Sources by GO-SWCNT Buckypapers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drinking Water; Environmental Pollutants; Ketoprofen; Naproxen | 2022 |
Evaluation of the Defined Bacterial Consortium Efficacy in the Biodegradation of NSAIDs.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Naproxen; Sewage | 2023 |
Dissemination of nonsteroidal anti-inflammatory drugs (NSAIDs) and metabolites from wastewater treatment plant to soils and agricultural crops via real-scale different agronomic practices.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Crops, Agricultural; Diclofenac; Naproxen; Sewage; Soil; Sugars; Vegetables; Wastewater | 2023 |
Impact of Lifestyle and Socioeconomic Position on the Association Between Non-steroidal Anti-inflammatory Drug Use and Major Adverse Cardiovascular Events: A Case-Crossover Study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cross-Over Studies; Diclofenac; Humans; Ibuprofen; Life Style; Myocardial Infarction; Naproxen; Risk Factors; Socioeconomic Factors | 2023 |
Impact of hemoglobin A1c level on the association between non-steroidal anti-inflammatory drug use and cardiovascular events in patients with type 2 diabetes: A population-based cohort study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Diabetes Mellitus, Type 2; Diclofenac; Glycated Hemoglobin; Humans; Ibuprofen; Myocardial Infarction; Naproxen; Risk Factors | 2023 |
Cardiovascular risks of continuing vs. initiating NSAIDs after first-time myocardial infarction or heart failure: a nationwide cohort study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cohort Studies; Diclofenac; Heart Disease Risk Factors; Heart Failure; Humans; Ibuprofen; Myocardial Infarction; Naproxen; Risk Factors | 2023 |
Effect of salinity on the toxicity of diclofenac, ibuprofen and naproxen toward cyanobacterium Synechocystis salina.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Naproxen; Salinity; Water Pollutants, Chemical | 2023 |
The suppression of MAPK/NOX/MMP signaling prompts renoprotection conferred by prenatal naproxen in weaning preeclamptic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Diclofenac; Female; Humans; Naproxen; Pre-Eclampsia; Pregnancy; Rats; Vitamins; Weaning | 2023 |