diclofenac and naltrexone

diclofenac has been researched along with naltrexone in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (36.36)29.6817
2010's14 (63.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Chang, TK; Ensom, MH; Kiang, TK1
Jolivette, LJ; Ward, KW1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hodgson, DM; Taylor, AN; Yirmiya, R1
Booker, L; Cravatt, BF; Lichtman, AH; Naidu, PS1
Bakhle, YS; de Francischi, JN; dos Reis, WG; Ferreira-Alves, DL; Gassani, BC; Paiva-Lima, P; Rezende, RM1
Banks, SL; Brogden, NK; Loftin, CD; Paudel, KS; Stinchcomb, AL1
Esrafili, A; Rezazadeh, M; Seidi, S; Yamini, Y1
Ghosh, P; Hammell, DC; Paudel, KS; Pinninti, RR; Stinchcomb, AL1
Banks, SL; Brogden, NK; Crofford, LJ; Stinchcomb, AL1
Ghosh, P; Kim, KB; Lee, D; Stinchcomb, AL1
King, T; Navratilova, E; Okun, A; Porreca, F; Remeniuk, B; Sukhtankar, D; Xie, JY1
Baharfar, M; Faraji, M; Yamini, Y; Zarghampour, F1

Reviews

2 review(s) available for diclofenac and naltrexone

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for diclofenac and naltrexone

ArticleYear
Diclofenac enables unprecedented week-long microneedle-enhanced delivery of a skin impermeable medication in humans.
    Pharmaceutical research, 2013, Volume: 30, Issue:8

    Topics: Administration, Cutaneous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Delivery Systems; Female; Humans; Male; Microinjections; Naltrexone; Narcotic Antagonists; Needles; Skin Absorption; Young Adult

2013

Other Studies

19 other study(ies) available for diclofenac and naltrexone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Intracerebroventricular interleukin-1beta impairs clearance of tumor cells from the lungs: role of brain prostaglandins.
    Journal of neuroimmunology, 2001, Sep-03, Volume: 119, Issue:1

    Topics: Adenocarcinoma; Animals; Brain; Cyclooxygenase Inhibitors; Diclofenac; Ibuprofen; Injections, Intraventricular; Interleukin-1; Lung Neoplasms; Male; Naltrexone; Narcotic Antagonists; Neoplasm Invasiveness; Neural Pathways; Norepinephrine; Prostaglandins; Rats; Rats, Inbred F344

2001
Synergy between enzyme inhibitors of fatty acid amide hydrolase and cyclooxygenase in visceral nociception.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:1

    Topics: Acetic Acid; Amidohydrolases; Animals; Benzamides; Carbamates; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Protective Agents; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Stomach Ulcer

2009
Is the sulphonamide radical in the celecoxib molecule essential for its analgesic activity?
    Pharmacological research, 2010, Volume: 62, Issue:5

    Topics: Acetazolamide; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Hyperalgesia; Inflammation; Male; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides

2010
Diclofenac enables prolonged delivery of naltrexone through microneedle-treated skin.
    Pharmaceutical research, 2011, Volume: 28, Issue:5

    Topics: Animals; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Diclofenac; Guinea Pigs; Naltrexone; Narcotic Antagonists; Skin; Skin Absorption; Transdermal Patch

2011
Low-voltage electrically-enhanced microextraction as a novel technique for simultaneous extraction of acidic and basic drugs from biological fluids.
    Journal of chromatography. A, 2012, Jun-22, Volume: 1243

    Topics: Chromatography, High Pressure Liquid; Diclofenac; Electrochemical Techniques; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Limit of Detection; Liquid Phase Microextraction; Membranes, Artificial; Naltrexone; Pharmaceutical Preparations; Reproducibility of Results; Sodium Hydroxide; Solvents

2012
Development of a codrug approach for sustained drug delivery across microneedle-treated skin.
    Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:5

    Topics: Administration, Cutaneous; Animals; Cyclooxygenase Inhibitors; Diclofenac; Drug Delivery Systems; Guinea Pigs; Naltrexone; Narcotic Antagonists; Needles; Skin; Skin Absorption; Swine; Transdermal Patch

2013
Optimization of naltrexone diclofenac codrugs for sustained drug delivery across microneedle-treated skin.
    Pharmaceutical research, 2014, Volume: 31, Issue:1

    Topics: Administration, Cutaneous; Animals; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Drug Delivery Systems; Drug Stability; Naltrexone; Needles; Permeability; Polyethylene Glycols; Skin; Skin Absorption; Solubility; Swine

2014
Behavioral and neurochemical analysis of ongoing bone cancer pain in rats.
    Pain, 2015, Volume: 156, Issue:10

    Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Bone Neoplasms; Cell Line, Tumor; Diclofenac; Disease Models, Animal; Female; Gyrus Cinguli; Lidocaine; Morphine; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Pain; Rats; Rats, Inbred F344

2015
Simultaneous extraction of acidic and basic drugs via on-chip electromembrane extraction using a single-compartment microfluidic device.
    The Analyst, 2019, Feb-11, Volume: 144, Issue:4

    Topics: Chromatography, High Pressure Liquid; Diclofenac; Electrochemical Techniques; Lab-On-A-Chip Devices; Membranes, Artificial; Naltrexone; Polymethyl Methacrylate; Time Factors

2019