diclofenac and nabumetone

diclofenac has been researched along with nabumetone in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	15 (42.86)	18.2507
2000's	14 (40.00)	29.6817
2010's	6 (17.14)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Blower, PR; Gentry, C; Melarange, R; O'Connell, C	1
Fehilly, B; Laws, D; Saul, S	1
Grossi, E; Miriano, F; Movilia, P; Restelli, L; Vaiani, G	1
Bjarnason, I; Hayllar, J	1
Blower, P; Melarange, R; Spangler, R	1
DeLapp, RE; Eversmeyer, W; Jensen, CP; Poland, M	1
DeLapp, RE; Morgan, GJ; Poland, M	1
DeLapp, RE; Lister, BJ; Poland, M	1
Ahmad, S; Beaulieu, A; Bell, MJ; Bellamy, N; Bensen, WG; Davis, P; Khanna, VN; Kraag, GR; Lussier, A; Siminovitch, KA	1
Carryl, OR; Spangler, RS	1
Gijón Baños, J	1
Lindsley, HB; Schwartzenberg, JM; Smith, DD	1
Agrawal, NM; Ball, J; Bocanegra, TS; Caldwell, J; Dhadda, S; Hancock, L; Hurley, S; Kivitz, AJ; Weaver, AL	1
Becvár, R; Bereczki, J; Bernacka, K; Ehrenfeld, M; Filipowicz-Sosnowska, A; Gömör, B; Green, L; Mackiewicz, S; Maldyk, H; Pavelka, K; Rojkovich, B; Rybár, I; Siro, B; Sukenik, S; Toth, K; Urbanová, Z; Vítová, J; Vlasáková, V	1
Bolognese, JA; Harper, SE; Jensen, DM; Langman, MJ; Quan, H; Simon, TJ; Watson, DJ; Zhao, PL	1
DeLapp, R; Kaine, J; Morgan , GJ; Palmer, R	1
Browning, RA; Burgess, FW	1
Barr, E; Reicin, AS; Shapiro, D; Sperling, RS; Yu, Q	1
Bolognese, JA; Harper, SE; Simon, TJ; Watson, DJ; Zhao, PL	1
Bolognese, JA; Gertz, BJ; Krupa, D; Reicin, A; Sperling, RS	1
Chen, BY; Cheng, NN; Li, D; Shi, W; Wang, YM	1
Chen, BY; Cheng, NN; Li, D; Li, SL; Shi, W; Wang, YM; Yan, M	1
Ashworth, NL; Muhajarine, N; Peloso, PM; Stang, M	2
Bjarnason, I; Bjornsson, E; Maiden, L; Premchand, P; Sherwood, R; Smale, S; Takeuchi, K; Thjodleifsson, B	1
Capron, L; Lillo-Le Louët, A; Vautier, S; Wyplosz, B	1
Arimori, K; Chosa, E; Fujita, K; Kawai, K; Nishio, T; Ogata, K; Setoguchi, N; Takamura, N; Tokunaga, J; Yamamoto, R	1
Changchien, E; Chiang, CH; Chin, HY; Lin, MF; Wang, CJ	1
Cho, CS; Kang, YM; Kim, JH; Kim, SK; Lee, DH; Lee, SK; Lee, ST; Lee, YC; Park, SH; Park, W; Park, YW; Rew, JS; Yoo, WH	1

Reviews

3 review(s) available for diclofenac and nabumetone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Adverse upper gastrointestinal effects of rofecoxib compared with NSAIDs. JAMA, 1999, Nov-24, Volume: 282, Issue:20 Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Nabumetone; Osteoarthritis; Peptic Ulcer; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Randomized Controlled Trials as Topic; Sulfones	1999
[Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs]. Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2003, Volume: 24, Issue:11 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; China; Diclofenac; Humans; Ibuprofen; Meloxicam; Nabumetone; Naproxen; Osteoarthritis; Oxaprozin; Propionates; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiazoles	2003

Trials

13 trial(s) available for diclofenac and nabumetone

Article	Year
A microcomputer-assisted study of nabumetone and slow release diclofenac in osteoarthritis. Drugs, 1990, Volume: 40 Suppl 5 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Delayed-Action Preparations; Diclofenac; Double-Blind Method; Female; Humans; Male; Microcomputers; Middle Aged; Nabumetone; Osteoarthritis; Pain Measurement	1990
Analgesic activity of nabumetone in postoperative pain. Drugs, 1990, Volume: 40 Suppl 5 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Carpal Tunnel Syndrome; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged; Nabumetone; Pain, Postoperative; Pilot Projects; Piroxicam	1990
Safety experience with nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis. The American journal of medicine, 1993, Aug-09, Volume: 95, Issue:2A Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam	1993
Efficacy and safety of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in the elderly. The American journal of medicine, 1993, Aug-09, Volume: 95, Issue:2A Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Male; Nabumetone; Naproxen; Osteoarthritis; Piroxicam	1993
Efficacy of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis. The American journal of medicine, 1993, Aug-09, Volume: 95, Issue:2A Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Life Style; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam	1993
A multicenter study of nabumetone and diclofenac SR in patients with osteoarthritis. The Journal of rheumatology, 1995, Volume: 22, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Diclofenac; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Nabumetone; Osteoarthritis	1995
[Efficacy and safety of nabumetone in the treatment of knee osteoarthritis: a comparative clinical trial versus aceclofenac. Study Group of Nabumetone for Osteoarthritis of the Knee]. Medicina clinica, 1997, Jun-21, Volume: 109, Issue:4 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Diclofenac; Female; Humans; Knee Joint; Male; Middle Aged; Nabumetone; Osteoarthritis	1997
Comparison of the upper gastrointestinal safety of Arthrotec 75 and nabumetone in osteoarthritis patients at high risk for developing nonsteroidal anti-inflammatory drug-induced gastrointestinal ulcers. Clinical therapeutics, 1999, Volume: 21, Issue:4 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Diclofenac; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Misoprostol; Nabumetone; Osteoarthritis; Peptic Ulcer; Risk	1999
Nabumetone induces less gastrointestinal mucosal changes than diclofenac retard. Clinical rheumatology, 1999, Volume: 18, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Diclofenac; Endoscopy, Digestive System; Gastric Mucosa; Gastrointestinal Diseases; Humans; Intestinal Mucosa; Middle Aged; Nabumetone; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Measurement; Safety; Treatment Outcome	1999
Treatment of elderly patients with nabumetone or diclofenac: gastrointestinal safety profile. Journal of clinical gastroenterology, 2001, Volume: 32, Issue:4 Topics: Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Diclofenac; Digestive System; Double-Blind Method; Female; Humans; Liver; Male; Nabumetone; Osteoarthritis; Peptic Ulcer; Peptic Ulcer Hemorrhage; Treatment Outcome	2001
[Comparison of the efficacy and safety of nabumetone and diclofenac sodium in the treatment of patients with rheumatoid arthritis]. Zhonghua yi xue za zhi, 2001, May-10, Volume: 81, Issue:9 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Nabumetone; Peptic Ulcer	2001
A diclofenac suppository-nabumetone combination therapy for arthritic pain relief and a monitoring method for the diclofenac binding capacity of HSA site II in rheumatoid arthritis. Biopharmaceutics & drug disposition, 2013, Volume: 34, Issue:2 Topics: Aged; Arthritis, Rheumatoid; Binding Sites; Butanones; Cyclooxygenase Inhibitors; Diclofenac; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nabumetone; Pain; Protein Binding; Serum Albumin; Suppositories	2013
Preventive efficacy and safety of rebamipide in nonsteroidal anti-inflammatory drug-induced mucosal toxicity. Gut and liver, 2014, Volume: 8, Issue:4 Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Butanones; Diclofenac; Double-Blind Method; Drug Administration Schedule; Gastric Mucosa; Humans; Meloxicam; Middle Aged; Misoprostol; Nabumetone; Quinolones; Stomach Ulcer; Thiazines; Thiazoles; Treatment Outcome	2014

Other Studies

19 other study(ies) available for diclofenac and nabumetone

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Anti-inflammatory efficacy and gastrointestinal irritancy: comparative 1 month repeat oral dose studies in the rat with nabumetone, ibuprofen and diclofenac. Agents and actions. Supplements, 1991, Volume: 32 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Butanones; Carrageenan; Diclofenac; Edema; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Ibuprofen; Male; Nabumetone; Rats; Rats, Inbred Strains	1991
NSAIDs, Cox-2 inhibitors, and the gut. Lancet (London, England), 1995, Aug-26, Volume: 346, Issue:8974 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cyclooxygenase Inhibitors; Diclofenac; Digestive System; Humans; Indans; Nabumetone; Naproxen; Oxidative Phosphorylation; Piroxicam; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases	1995
Comparison of the anti-inflammatory activity and gastrointestinal irritancy of nabumetone, ibuprofen, and diclofenac in rats following chronic administration. European journal of rheumatology and inflammation, 1994, Volume: 14, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Carrageenan; Cecum; Diclofenac; Digestive System; Drug Administration Schedule; Gastric Mucosa; Gastrointestinal Diseases; Haptoglobins; Hemoglobins; Ibuprofen; Ileum; Male; Nabumetone; Rats; Rats, Wistar	1994
Comparative effects of nabumetone, naproxen, piroxicam, and diclofenac on rat gastric irritancy following acute exposure to OTC non-steroidal anti-inflammatory agents and other gastric irritants. Scandinavian journal of rheumatology, 1995, Volume: 24, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Diclofenac; Gastric Mucosa; Male; Nabumetone; Naproxen; Nonprescription Drugs; Piroxicam; Rats; Rats, Wistar	1995
Bacillus Calmette-Guérin associated arthropathy mimicking undifferentiated spondyloarthropathy. The Journal of rheumatology, 1999, Volume: 26, Issue:4 Topics: Arthritis, Reactive; BCG Vaccine; Butanones; Carcinoma, Transitional Cell; Cytokines; Diagnosis, Differential; Diclofenac; Enzyme-Linked Immunosorbent Assay; Glucocorticoids; Humans; Joint Diseases; Male; Middle Aged; Nabumetone; Spondylitis, Ankylosing; Toe Joint; Urinary Bladder Neoplasms	1999
Nonsteroidal anti-inflammatory drugs for perioperative pain control. Medicine and health, Rhode Island, 2001, Volume: 84, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Etodolac; Humans; Ibuprofen; Indomethacin; Ketorolac; Lactones; Nabumetone; Naproxen; Pain, Postoperative; Piroxicam; Pyrazoles; Sulfonamides; Sulfones; Time Factors	2001
Comparison of cardiovascular thrombotic events in patients with osteoarthritis treated with rofecoxib versus nonselective nonsteroidal anti-inflammatory drugs (ibuprofen, diclofenac, and nabumetone). The American journal of cardiology, 2002, Jan-15, Volume: 89, Issue:2 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cardiovascular Diseases; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diclofenac; Female; Humans; Ibuprofen; Incidence; Lactones; Male; Middle Aged; Nabumetone; Osteoarthritis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Risk; Sulfones; Thrombosis; Treatment Outcome	2002
Gastrointestinal medications and procedures in osteoarthritis patients treated with rofecoxib compared with nonselective NSAIDs. MedGenMed : Medscape general medicine, 2001, Nov-16, Volume: 3, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Lactones; Male; Middle Aged; Nabumetone; Osteoarthritis; Randomized Controlled Trials as Topic; Sulfones	2001
A comparison of adverse renovascular experiences among osteoarthritis patients treated with rofecoxib and comparator non-selective non-steroidal anti-inflammatory agents. Current medical research and opinion, 2002, Volume: 18, Issue:2 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Edema; Female; Humans; Hypertension; Ibuprofen; Isoenzymes; Lactones; Male; Membrane Proteins; Nabumetone; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Renal Circulation; Safety; Sulfones	2002
Risk factors of adverse drug reaction from non-steroidal anti-inflammatory drugs in Shanghai patients with arthropathy. Acta pharmacologica Sinica, 2004, Volume: 25, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Child; Diclofenac; Dizziness; Exanthema; Female; Gastrointestinal Hemorrhage; Humans; Male; Meloxicam; Middle Aged; Nabumetone; Osteoarthritis; Retrospective Studies; Risk Factors; Spondylitis, Ankylosing; Stomach Diseases; Thiazines; Thiazoles	2004
A population based historical cohort study of the mortality associated with nabumetone, Arthrotec, diclofenac, and naproxen. The Journal of rheumatology, 2004, Volume: 31, Issue:5 Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cause of Death; Chronic Disease; Cohort Studies; Diclofenac; Drug Combinations; Female; Humans; Logistic Models; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Risk; Saskatchewan; Survival Rate	2004
Risk of hospitalization with peptic ulcer disease or gastrointestinal hemorrhage associated with nabumetone, Arthrotec, diclofenac, and naproxen in a population based cohort study. The Journal of rheumatology, 2005, Volume: 32, Issue:11 Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cohort Studies; Databases, Factual; Diclofenac; Drug Combinations; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Peptic Ulcer; Risk Factors; Saskatchewan	2005
Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006, Volume: 4, Issue:2 Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Colitis, Ulcerative; Crohn Disease; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Indomethacin; Inflammatory Bowel Diseases; Male; Middle Aged; Nabumetone; Naproxen; Prevalence; Recurrence; Sulfonamides	2006
Tolerance of diclofenac after hypersensitivity to celecoxib and to nabumetone. British journal of clinical pharmacology, 2006, Volume: 61, Issue:4 Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Drug Hypersensitivity; Female; Humans; Knee Joint; Nabumetone; Osteoarthritis; Pyrazoles; Sulfonamides; Treatment Outcome	2006
Concentration of non-steroidal anti-inflammatory drugs in the pelvic floor muscles: an experimental comparative rat model. Yonsei medical journal, 2014, Volume: 55, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Chronic Pain; Diclofenac; Female; Meloxicam; Muscles; Nabumetone; Naproxen; Pelvic Floor; Pelvic Pain; Piroxicam; Rats; Rats, Wistar; Thiazines; Thiazoles	2014