diclofenac and misoprostol

diclofenac has been researched along with misoprostol in 94 studies

Research

Studies (94)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's54 (57.45)18.2507
2000's26 (27.66)29.6817
2010's12 (12.77)24.3611
2020's2 (2.13)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Doherty, M1
de Melo Gomes, JA1
Geis, GS3
Karim, A; Smith, M1
Bach, GL1
Knill-Jones, RP1
Hannequin, JR1
Bolten, W; Geis, GS; Gomes, JA; Stead, H1
Fraga, AM; Geis, GS; Hantzschel, H; Moran, C; Stead, H; Verdickt, W1
Boers, M; Breedveld, FC; Camps, JA; Cats, A; Chang, PC; Dijkmans, BA; Pauwels, EK; Van Brummelen, P1
Broen, JJ; Cafruny, WA; DesJarlais, SE; Hecht, ML; Jaqua, RA1
Geis, GS; Nicholson, PA; Stead, H; Wallemark, CB1
Mowat, AG1
McKenna, F4
Kiff, PS; Morant, SV; Shield, MJ; Stead, H1
Bortolussi, R; Bortoluzzi, F; Cannizzaro, R; Fornasarig, M; Fracasso, A; Grazioli, I; Poletti, M; Sozzi, M; Testa, V; Valentini, M1
Cirino, G; Elliott, SN; McKnight, W; Wallace, JL1
Perkins, WE; Rainsford, KD; Stetsko, PI1
Downie, WW1
Zuinen, C1
Gagnier, P1
Karim, A1
Burtsev, VI; Chichasova, NV; Krikunov, VP; Kuzin, AV; Lebedeva, OI; Murav'ev, IuV; Nasonov, EL; Nasonova, VA; Rashchupkina, ZP; Sigidin, IaA1
Agrawal, NM; Erhardt, LJ; Geis, GS; Van Kerckhove, HE1
Beaulieu, A; de Queiroz, MV; Geis, S; Kruger, K; Stead, H; Woods, E1
Jackisch, P; Müller, P; Simon, B1
McKnight, GW; Wallace, JL1
Cullen, D; Hawkey, CJ1
Bruyn, GA; Geis, GS; Melo Gomes, JA; Roth, SH; Woods, EM; Zeeh, J1
Davis, R; Goa, KL; Yarker, YE1
Baltoyiannis, G; Cassioumis, D; Fatouros, M; Giannoukas, AD; Kappas, AM; Milonakis, M; Nastos, D; Papadimitriou, C; Papagikos, L1
Armstrong, D; Blum, AL; Dorta, G; Margalith, D; Nicolet, M; Saraga, E; Vouillamoz, D1
Silverstein, FE1
Chandler, C; Heslop, P; Walker, DJ1
Shield, MJ1
Ghosh, D; Nayak, NR; Sengupta, J2
Ball, JA; Bocanegra, TS; Fort, JG; Geis, GS; Sikes, DH; Tindall, EA; Wallemark, CB; Weaver, AL1
Al, MJ; Michel, BC; Rutten, FF1
Goldstein, JL; Larson, LR; Yamashita, BD1
Agrawal, NM; Ball, J; Bocanegra, TS; Caldwell, J; Dhadda, S; Hancock, L; Hurley, S; Kivitz, AJ; Weaver, AL1
Christophidis, N; Mander, A; Scharf, S; Ugoni, A; Vajda, F1
Morgan, D1
Andrews, P; Ecelbarger, CA; Fernández-Llama, P; Knepper, MA; Lee, AJ; Nielsen, S; Turner, R; Ware, JA1
Devins, GM; Edworthy, SM1
Lamb, HM; Plosker, GL1
Kristiansen, IS; Kvien, TK; Nord, E1
Dediunina, RS; Filonenko, SP; Iakushin, SS; Lukina, IM1
Mateos García, E; Medina Santillán, R; Reyes García, G1
Mohammed, EP; Stevens, JM1
Dedhiya, S; Kosinski, M; Osterhaus, JT; Ware, JE; Zhao, SZ1
Soto Alvarez, J1
Acevedo, E; Beaulieu, AD; Caeiro, F; Casas, N; Castañeda, O; Garza-Elizondo, M; Gutierrez-Ureña, S; Hinojosa, W; Irazoque, F; Laurenzi, M; Pons-Estel, B; Rodgers, DB; Ugaz, M; Vandormael, K1
Araki, H; Arizono, N; Kakehi, K; Kawabata, A; Kinoshita, M; Kuroda, R; Nishida, M; Nishikawa, H; Oda, Y1
Joseph, L; Kong, SX; LeLorier, J; Pellissier, JM; Rahme, E; Watson, DJ1
Abramson, SB; Caldwell, JR; Callahan, LF; Cummins, P; Fort, J; Harrell, RA; Jordan, JM; Koch, GG; Kremer, JM; Lautzenheiser, RL; Lefkowith, J; Luta, G; Markenson, JA; Morant, S; Pincus, T; Schnitzer, TJ; Schwartz, T; Sokka, T; Wang, X; Weaver, A; Wilson, A; Wolfe, F1
Chiloiro, M; Montanaro, S; Riezzo, G1
Blandino, D1
Pincus, T1
White, DP1
Isserow, SH; Schellenberg, RR1
Ravaud, P1
Anderson, GM; Austin, PC; Juurlink, DN; Kopp, A; Laupacis, A; Mamdani, M; Naglie, G; Rochon, PA1
Chan, CP; Ho, PC; Li, CF; Wong, CY1
Bellorini, M; Funck, F; Guillard, N; Jourdain, P; Loiret, J; Meuleman, C; Sadeg, N; Thebault, B1
Damaschke, A; Dammann, HG; Sallowsky, E; Schmoldt, A; Simon-Schultz, J; Steinhoff, I1
Oviedo, JA; Wolfe, MM1
Ashworth, NL; Muhajarine, N; Peloso, PM; Stang, M2
Chung, C; Koch, GG; Pincus, T; Sokka, T; Wang, X1
Fiala, C; Gemzell-Danielsson, K; Stephansson, O; Swahn, ML1
Ateshkadi, A; Barri, YM; Cheung, AK; Gardner, SF; Munger, MA; Rabetoy, GM; Stoddard, GJ1
Déciga-Campos, M; Granados-Soto, V; Medina-Santillan, R; Reyes-García, G1
Ehara, A; Fujimori, S; Gudis, K; Kobayashi, T; Mitsui, K; Sakamoto, C; Seo, T; Tanaka, S; Tatsuguchi, A; Yonezawa, M1
Herrerías Gutiérrez, JM; Romero Vázquez, J1
Böttcher, A; Guder, E; Just, T1
Ibrahim, ZM; Sayed Ahmed, WA1
Hamura, K; Matsuo, H; Yokooji, T1
Amagase, K; Satoh, H; Takeuchi, K1
Carter, H; Gazet, AC; Pillai, M; Sedgeman, K; Staddon, J; Welsh, V1
Cho, JW; Choi, MG; Chung, IK; Jang, JY; Kang, DH; Kim, JI; Kim, KO; Kim, TO; Lee, DH; Lee, KM; Lee, OY; Lee, ST; Lee, SW; Rew, JS; Seol, SY; Shin, YW1
Cho, CS; Kang, YM; Kim, JH; Kim, SK; Lee, DH; Lee, SK; Lee, ST; Lee, YC; Park, SH; Park, W; Park, YW; Rew, JS; Yoo, WH1
Lusthof, KJ; Schweer, H; Watzer, B1
Aydogmus, Y; Buyukserbetci, M; Dadali, M; Eroglu, M; Hascicek, AM; Huri, E; Kilinc, AS; Ogus, E; Ozer, E1
Andersen, JT; Andersen, NL; Broedbaek, K; Cejvanovic, V; Jimenez-Solem, E; Mastrogiannis, D; Nielsen, TK; Petersen, M; Poulsen, HE1
Ciebiera, M; Filipowska, J; Kluz, T; Ludwin, A; Węgrzyn, P; Zgliczyńska, M; Łoziński, T1
Cheung, AK; Munger, MA; Nelson, SD; Sauer, BC; Teng, CC1

Reviews

16 review(s) available for diclofenac and misoprostol

ArticleYear
Overall safety of Arthrotec.
    Scandinavian journal of rheumatology. Supplement, 1992, Volume: 96

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Constipation; Diarrhea; Diclofenac; Dizziness; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Misoprostol; Osteoarthritis; Pain; Vomiting

1992
Biopharmaceutical profile of diclofenac-misoprostol combination tablet, Arthrotec.
    Scandinavian journal of rheumatology. Supplement, 1992, Volume: 96

    Topics: Administration, Oral; Biological Availability; Diclofenac; Drug Combinations; Half-Life; Humans; Misoprostol; Tablets

1992
The economic consequences of NSAID-induced gastropathy in the United Kingdom and commentary on the article by G. de Pouvourville.
    Scandinavian journal of rheumatology. Supplement, 1992, Volume: 96

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cost of Illness; Diclofenac; Drug Combinations; Gastrointestinal Diseases; Humans; Misoprostol; National Health Programs; Rheumatic Diseases; United Kingdom

1992
Review of Arthrotec clinical data.
    European journal of rheumatology and inflammation, 1994, Volume: 14, Issue:3 Suppl

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diclofenac; Drug Combinations; Humans; Misoprostol

1994
Diclofenac/misoprostol. A review of the major clinical trials evaluating its clinical efficacy and upper gastrointestinal tolerability in rheumatoid arthritis and osteoarthritis.
    Drugs, 1993, Volume: 45 Suppl 1

    Topics: Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Drug Combinations; Humans; Misoprostol; Osteoarthritis

1993
Review of the safety of diclofenac/misoprostol.
    Drugs, 1993, Volume: 45 Suppl 1

    Topics: Arthritis, Rheumatoid; Diclofenac; Drug Combinations; Humans; Misoprostol; Osteoarthritis; Safety; Spondylitis, Ankylosing

1993
Efficacy and gastroduodenal safety of a fixed combination of diclofenac and misoprostol in the treatment of arthritis.
    British journal of rheumatology, 1995, Volume: 34 Suppl 1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Drug Combinations; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Misoprostol; Stomach Ulcer

1995
Arthrotec: a therapeutic option in the management of arthritis.
    European journal of rheumatology and inflammation, 1993, Volume: 13, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Combinations; Humans; Misoprostol; Multicenter Studies as Topic; Randomized Controlled Trials as Topic

1993
Diclofenac/misoprostol. A review of its pharmacology and therapeutic efficacy in painful inflammatory conditions.
    Drugs & aging, 1995, Volume: 7, Issue:5

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Clinical Trials as Topic; Cost-Benefit Analysis; Diclofenac; Duodenal Ulcer; Humans; Misoprostol; Stomach Ulcer

1995
Improving the gastrointestinal safety of NSAIDs: the development of misoprostol--from hypothesis to clinical practice.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Diclofenac; Drug Combinations; History, 20th Century; Humans; Misoprostol; Peptic Ulcer

1998
Diclofenac/misoprostol: novel findings and their clinical potential.
    The Journal of rheumatology. Supplement, 1998, Volume: 51

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Combinations; Drug Synergism; Hemoglobins; Humans; Misoprostol; Rheumatic Diseases

1998
Prevention of nonsteroidal anti-inflammatory drug-induced gastropathy: clinical and economic implications of a single-tablet formulation of diclofenac/misoprostol.
    The American journal of managed care, 1998, Volume: 4, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Canada; Cost of Illness; Diclofenac; Drug Combinations; Humans; Misoprostol; Models, Econometric; Risk Factors; Stomach Diseases; United States

1998
Arthrotec: the evidence speaks for itself.
    Scandinavian journal of rheumatology. Supplement, 1999, Volume: 109

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Drug Combinations; Evidence-Based Medicine; Humans; Misoprostol

1999
Diclofenac/misoprostol. Pharmacoeconomic implications of therapy.
    PharmacoEconomics, 1999, Volume: 16, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Costs and Cost Analysis; Diclofenac; Drug Combinations; Drug Evaluation; Economics, Pharmaceutical; Humans; Misoprostol; New Zealand; Peptic Ulcer; Protective Agents

1999
Clinical evidence for osteoarthritis as an inflammatory disease.
    Current rheumatology reports, 2001, Volume: 3, Issue:6

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Combinations; Humans; Inflammation; Middle Aged; Misoprostol; Osteoarthritis; Risk Factors; Socioeconomic Factors

2001
Gastroprotection by coxibs: what do the Celecoxib Long-Term Arthritis Safety Study and the Vioxx Gastrointestinal Outcomes Research Trial tell us?
    Rheumatic diseases clinics of North America, 2003, Volume: 29, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Enzyme Inhibitors; Gastrointestinal Hemorrhage; Humans; Lactones; Misoprostol; Omeprazole; Osteoarthritis; Proton Pump Inhibitors; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Sulfones

2003

Trials

43 trial(s) available for diclofenac and misoprostol

ArticleYear
The efficacy of Arthrotec in the treatment of osteoarthritis.
    Scandinavian journal of rheumatology. Supplement, 1992, Volume: 96

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Hip Joint; Humans; Knee Joint; Male; Middle Aged; Misoprostol; Osteoarthritis; Severity of Illness Index

1992
The safety of Arthrotec in patients with rheumatoid arthritis or osteoarthritis: an assessment of the upper gastrointestinal tract by endoscopy.
    Scandinavian journal of rheumatology. Supplement, 1992, Volume: 96

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Diclofenac; Digestive System; Double-Blind Method; Drug Combinations; Endoscopy; Female; Gastrointestinal Diseases; Humans; Intestinal Mucosa; Male; Middle Aged; Misoprostol; Osteoarthritis

1992
Overall safety of Arthrotec.
    Scandinavian journal of rheumatology. Supplement, 1992, Volume: 96

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Constipation; Diarrhea; Diclofenac; Dizziness; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Misoprostol; Osteoarthritis; Pain; Vomiting

1992
Efficacy of Arthrotec in the treatment of rheumatoid arthritis.
    Scandinavian journal of rheumatology. Supplement, 1992, Volume: 96

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Misoprostol

1992
The gastroduodenal safety and efficacy of the fixed combination of diclofenac and misoprostol in the treatment of osteoarthritis.
    British journal of rheumatology, 1992, Volume: 31, Issue:11

    Topics: Adult; Aged; Diclofenac; Double-Blind Method; Drug Combinations; Duodenum; Female; Gastrointestinal Diseases; Humans; Liver; Male; Middle Aged; Misoprostol; Osteoarthritis; Peptic Ulcer; Severity of Illness Index; Stomach

1992
A double-blind comparison of the gastroduodenal safety and efficacy of diclofenac and a fixed dose combination of diclofenac and misoprostol in the treatment of rheumatoid arthritis.
    Scandinavian journal of rheumatology, 1992, Volume: 21, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Diclofenac; Digestive System; Double-Blind Method; Drug Therapy, Combination; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Misoprostol; Stomach Ulcer

1992
No effect of misoprostol on renal function of rheumatoid patients treated with diclofenac.
    British journal of rheumatology, 1991, Volume: 30, Issue:1

    Topics: Adult; Aged; Alprostadil; Arthritis, Rheumatoid; Creatinine; Diclofenac; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Misoprostol; Severity of Illness Index

1991
Arthrotec, diclofenac and ibuprofen in general practice.
    European journal of rheumatology and inflammation, 1994, Volume: 14, Issue:3 Suppl

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Drug Combinations; Female; Humans; Ibuprofen; Male; Middle Aged; Misoprostol

1994
Nonsteroidal antiinflammatory drugs for cancer pain: comparison between misoprostol and ranitidine in prevention of upper gastrointestinal damage.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Diclofenac; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Misoprostol; Neoplasms; Odds Ratio; Pain; Ranitidine; Risk Factors; Single-Blind Method; Stomach Ulcer

1995
Diclofenac/misoprostol. A review of the major clinical trials evaluating its clinical efficacy and upper gastrointestinal tolerability in rheumatoid arthritis and osteoarthritis.
    Drugs, 1993, Volume: 45 Suppl 1

    Topics: Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Drug Combinations; Humans; Misoprostol; Osteoarthritis

1993
Efficacy and upper GI safety of diclofenac/misoprostol, piroxicam and naproxen in patients with osteoarthritis.
    Drugs, 1993, Volume: 45 Suppl 1

    Topics: Diclofenac; Double-Blind Method; Drug Combinations; Female; Gastrointestinal Diseases; Humans; Male; Misoprostol; Naproxen; Osteoarthritis; Piroxicam; Safety

1993
Diclofenac/misoprostol vs diclofenac/placebo in treating acute episodes of tendinitis/bursitis of the shoulder.
    Drugs, 1993, Volume: 45 Suppl 1

    Topics: Adolescent; Adult; Aged; Bursitis; Diclofenac; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Male; Middle Aged; Misoprostol; Patient Satisfaction; Shoulder; Tendinopathy

1993
Efficacy of diclofenac/misoprostol vs diclofenac in the treatment of ankylosing spondylitis.
    Drugs, 1993, Volume: 45 Suppl 1

    Topics: Adolescent; Adult; Aged; Diclofenac; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Misoprostol; Patient Satisfaction; Spondylitis, Ankylosing

1993
Review of the safety of diclofenac/misoprostol.
    Drugs, 1993, Volume: 45 Suppl 1

    Topics: Arthritis, Rheumatoid; Diclofenac; Drug Combinations; Humans; Misoprostol; Osteoarthritis; Safety; Spondylitis, Ankylosing

1993
Pharmacokinetics of diclofenac and misoprostol when administered alone or as a combination product.
    Drugs, 1993, Volume: 45 Suppl 1

    Topics: Administration, Oral; Adult; Aged; Biological Availability; Diclofenac; Drug Combinations; Drug Interactions; Female; Humans; Intestinal Absorption; Male; Misoprostol

1993
[A trial of the use of the preparation Arthrotec for treating rheumatic diseases].
    Terapevticheskii arkhiv, 1995, Volume: 67, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Combinations; Female; Humans; Male; Middle Aged; Misoprostol; Remission Induction; Rheumatic Diseases; Russia; Tablets

1995
Misoprostol coadministered with diclofenac for prevention of gastroduodenal ulcers. A one-year study.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:5

    Topics: Arthritis, Rheumatoid; Diclofenac; Endoscopy, Gastrointestinal; Female; Humans; Incidence; Life Tables; Male; Middle Aged; Misoprostol; Osteoarthritis; Peptic Ulcer; Time Factors

1995
Double-blind comparison of the efficacy of diclofenac/misoprostol and diclofenac in the treatment of rheumatoid arthritis.
    European journal of rheumatology and inflammation, 1994, Volume: 14, Issue:2

    Topics: Arthritis, Rheumatoid; Cohort Studies; Diclofenac; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Misoprostol; Tablets, Enteric-Coated

1994
[Comparison of the protective effects of roxatidine and misoprostol on diclofenac gastroduodenal pathology. An endoscopic, controlled study of volunteers].
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:10

    Topics: Adult; Anti-Ulcer Agents; Delayed-Action Preparations; Diclofenac; Gastric Acid; Gastroscopy; Histamine H2 Antagonists; Humans; Misoprostol; Piperidines; Stomach Ulcer

1994
Double-blind comparison of efficacy and gastroduodenal safety of diclofenac/misoprostol, piroxicam, and naproxen in the treatment of osteoarthritis.
    Annals of the rheumatic diseases, 1993, Volume: 52, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Diclofenac; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Misoprostol; Naproxen; Osteoarthritis; Peptic Ulcer; Piroxicam

1993
Effects of misoprostol on healing and prevention of biopsy-induced gastroduodenal lesions occurring during the administration of diclofenac to volunteers.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Biopsy; Cross-Over Studies; Diclofenac; Double-Blind Method; Female; Humans; Male; Misoprostol; Peptic Ulcer

1996
Ambulatory activity as an objective and quantifiable measure of nonsteroidal therapy.
    The Journal of rheumatology, 1998, Volume: 25, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cross-Over Studies; Diclofenac; Double-Blind Method; Drug Combinations; Energy Metabolism; Female; Humans; Middle Aged; Misoprostol; Monitoring, Ambulatory; Outcome Assessment, Health Care; Walking

1998
Diclofenac/misoprostol: the European clinical experience.
    The Journal of rheumatology. Supplement, 1998, Volume: 51

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Drug Combinations; Duodenal Ulcer; Duodenoscopy; Gastroscopy; Humans; Misoprostol; Naproxen; Osteoarthritis; Piroxicam; Stomach Ulcer

1998
Diclofenac/misoprostol compared with diclofenac in the treatment of osteoarthritis of the knee or hip: a randomized, placebo controlled trial. Arthrotec Osteoarthritis Study Group.
    The Journal of rheumatology, 1998, Volume: 25, Issue:8

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Duodenal Ulcer; Endoscopy, Gastrointestinal; Female; Humans; Male; Middle Aged; Misoprostol; Osteoarthritis, Hip; Osteoarthritis, Knee; Outcome Assessment, Health Care; Stomach Ulcer; Treatment Failure

1998
The cost effectiveness of diclofenac plus misoprostol compared with diclofenac monotherapy in patients with rheumatoid arthritis.
    PharmacoEconomics, 1996, Volume: 10, Issue:2

    Topics: Age Factors; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Cost-Benefit Analysis; Diclofenac; Drug Combinations; Humans; Misoprostol; Models, Economic; Peptic Ulcer

1996
Comparison of the upper gastrointestinal safety of Arthrotec 75 and nabumetone in osteoarthritis patients at high risk for developing nonsteroidal anti-inflammatory drug-induced gastrointestinal ulcers.
    Clinical therapeutics, 1999, Volume: 21, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Diclofenac; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Misoprostol; Nabumetone; Osteoarthritis; Peptic Ulcer; Risk

1999
A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease.
    Neurology, 1999, Jul-13, Volume: 53, Issue:1

    Topics: Aged; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cognition; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Mental Status Schedule; Middle Aged; Misoprostol; Placebos; Time Factors; Treatment Outcome

1999
Improving medication adherence through patient education distinguishing between appropriate and inappropriate utilization. Patient Education Study Group.
    The Journal of rheumatology, 1999, Volume: 26, Issue:8

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Computer-Assisted Instruction; Decision Making; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Misoprostol; Osteoarthritis; Patient Compliance; Patient Education as Topic; Treatment Outcome

1999
Prevention of gastroduodenal injury induced by NSAIDs with low-dose misoprostol.
    Proceedings of the Western Pharmacology Society, 1999, Volume: 42

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Double-Blind Method; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Misoprostol; Stomach Ulcer

1999
Determining minimally important changes in generic and disease-specific health-related quality of life questionnaires in clinical trials of rheumatoid arthritis.
    Arthritis and rheumatism, 2000, Volume: 43, Issue:7

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Celecoxib; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Misoprostol; Pyrazoles; Quality of Life; Severity of Illness Index; Sickness Impact Profile; Sulfonamides; Surveys and Questionnaires; Treatment Outcome

2000
Tolerability profiles of rofecoxib (Vioxx) and Arthrotec. A comparison of six weeks treatment in patients with osteoarthritis.
    Scandinavian journal of rheumatology, 2001, Volume: 30, Issue:1

    Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diarrhea; Diclofenac; Double-Blind Method; Drug Combinations; Female; Humans; Lactones; Male; Middle Aged; Misoprostol; Osteoarthritis; Severity of Illness Index; Sulfones; Treatment Outcome

2001
A randomized, double-blind, crossover clinical trial of diclofenac plus misoprostol versus acetaminophen in patients with osteoarthritis of the hip or knee.
    Arthritis and rheumatism, 2001, Volume: 44, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cross-Over Studies; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Misoprostol; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Measurement; Patient Satisfaction; Treatment Outcome

2001
Protective effect of amtolmetin guacyl versus placebo diclofenac and misoprostol in healthy volunteers evaluated as gastric electrical activity in alcohol-induced stomach damage.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cross-Over Studies; Diclofenac; Double-Blind Method; Electrophysiology; Ethanol; Gastric Emptying; Gastric Mucosa; Glycine; Humans; Misoprostol; Pyrroles; Stomach

2001
A study of co-treatment of nonsteroidal anti-inflammatory drugs (NSAIDs) with misoprostol for cervical priming before suction termination of first trimester pregnancy.
    Contraception, 2003, Volume: 67, Issue:2

    Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cervix Uteri; Diclofenac; Double-Blind Method; Drug Interactions; Female; Humans; Misoprostol; Pain; Pregnancy; Pregnancy Trimester, First; Premedication; Prospective Studies; Suction

2003
Differential effects of misoprostol and ranitidine on the pharmacokinetics of diclofenac and gastrointestinal symptoms.
    British journal of clinical pharmacology, 1993, Volume: 36, Issue:4

    Topics: Administration, Oral; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Chromatography, High Pressure Liquid; Cross-Over Studies; Defecation; Diclofenac; Drug Combinations; Drug Interactions; Feces; Humans; Male; Misoprostol; Ranitidine

1993
Patient preference in a crossover clinical trial of patients with osteoarthritis of the knee or hip: face validity of self-report questionnaire ratings.
    The Journal of rheumatology, 2005, Volume: 32, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diclofenac; Double-Blind Method; Humans; Misoprostol; Osteoarthritis, Hip; Osteoarthritis, Knee; Patient Satisfaction; Reproducibility of Results; Surveys and Questionnaires

2005
The effect of non-steroidal anti-inflammatory drugs on medical abortion with mifepristone and misoprostol at 13-22 weeks gestation.
    Human reproduction (Oxford, England), 2005, Volume: 20, Issue:11

    Topics: Abdominal Pain; Abortifacient Agents, Nonsteroidal; Abortion, Induced; Acetaminophen; Administration, Intravaginal; Adult; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Diclofenac; Drug Therapy, Combination; Female; Gestational Age; Humans; Mifepristone; Misoprostol; Parity; Pregnancy; Pregnancy Trimester, Second

2005
Misoprostol effects on diclofenac-induced cardiorenal changes in salt-sensitive patients with hypertension: the MEDIC Study.
    Pharmacotherapy, 2008, Volume: 28, Issue:7

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cross-Over Studies; Diclofenac; Double-Blind Method; Humans; Hypertension; Kidney; Middle Aged; Misoprostol; Prospective Studies; Sodium Chloride

2008
Prevention of nonsteroidal anti-inflammatory drug-induced small-intestinal injury by prostaglandin: a pilot randomized controlled trial evaluated by capsule endoscopy.
    Gastrointestinal endoscopy, 2009, Volume: 69, Issue:7

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Diclofenac; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Misoprostol; Omeprazole; Prostaglandins E, Synthetic; Proton Pump Inhibitors; Single-Blind Method; Young Adult

2009
Sublingual misoprostol prior to insertion of a T380A intrauterine device in women with no previous vaginal delivery.
    The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception, 2013, Volume: 18, Issue:4

    Topics: Administration, Sublingual; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Therapy, Combination; Egypt; Female; Humans; Intrauterine Devices, Copper; Misoprostol; Oxytocics; Pain; Prosthesis Implantation; Single-Blind Method; Young Adult

2013
A comparative study of DA-9601 and misoprostol for prevention of NSAID-associated gastroduodenal injury in patients undergoing chronic NSAID treatment.
    Archives of pharmacal research, 2014, Volume: 37, Issue:10

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Double-Blind Method; Female; Humans; Middle Aged; Misoprostol; Peptic Ulcer; Plant Extracts; Young Adult

2014
Preventive efficacy and safety of rebamipide in nonsteroidal anti-inflammatory drug-induced mucosal toxicity.
    Gut and liver, 2014, Volume: 8, Issue:4

    Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Butanones; Diclofenac; Double-Blind Method; Drug Administration Schedule; Gastric Mucosa; Humans; Meloxicam; Middle Aged; Misoprostol; Nabumetone; Quinolones; Stomach Ulcer; Thiazines; Thiazoles; Treatment Outcome

2014
Oral misoprostol does not protect the kidneys from diclofenac induced toxicity: data from an unilateral ureteral obstructive rat model.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:18

    Topics: Administration, Oral; Animals; Diclofenac; Disease Models, Animal; Female; Kidney; Misoprostol; Rats; Rats, Wistar; Ureteral Obstruction

2015

Other Studies

38 other study(ies) available for diclofenac and misoprostol

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Anti-inflammatory efficacy versus gastrointestinal safety: a dilemma resolved? Introduction.
    Scandinavian journal of rheumatology. Supplement, 1992, Volume: 96

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Drug Combinations; Gastrointestinal Diseases; Humans; Misoprostol; Osteoarthritis; Rheumatic Diseases

1992
Enhancement of murine susceptibility to oral lactate dehydrogenase-elevating virus infection by non-steroidal anti-inflammatory agents, and antagonism by misoprostol.
    Antiviral research, 1991, Volume: 15, Issue:1

    Topics: Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Aspirin; Diclofenac; Female; Indomethacin; Lactate dehydrogenase-elevating virus; Mice; Mice, Inbred Strains; Misoprostol; Virus Diseases

1991
Prevalence of mucosal lesions in the stomach and duodenum due to chronic use of NSAID in patients with rheumatoid arthritis or osteoarthritis, and interim report on prevention by misoprostol of diclofenac associated lesions.
    The Journal of rheumatology. Supplement, 1991, Volume: 28

    Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Diclofenac; Duodenum; Female; Gastric Mucosa; Gastrointestinal Diseases; Humans; Incidence; Intestinal Mucosa; Male; Misoprostol; Osteoarthritis; Time Factors

1991
Arthrotec in general practice. Proceedings from the clinical investigator meeting held May 1994, Leeds, UK.
    European journal of rheumatology and inflammation, 1994, Volume: 14, Issue:3 Suppl

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Combinations; Family Practice; Humans; Misoprostol

1994
A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats.
    Gastroenterology, 1995, Volume: 109, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cyclooxygenase Inhibitors; Diclofenac; Gastric Acid; Hematocrit; Male; Misoprostol; Rats; Rats, Wistar; Stomach Ulcer; Thromboxane B2

1995
Chronic effects of misoprostol in combination with the NSAID, diclofenac, on gastrointestinal tract of pigs. Relation to diarrheagenic activity, leukocyte infiltration, and mucosal leukotrienes.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:7

    Topics: Animals; Biological Availability; Diarrhea; Diclofenac; Digestive System; Gastric Mucosa; Intestinal Mucosa; Leukocytes; Leukotrienes; Male; Misoprostol; Peroxidase; Swine

1995
Characterization of a simple animal model for nonsteroidal anti-inflammatory drug induced antral ulcer.
    Canadian journal of physiology and pharmacology, 1993, Volume: 71, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Indomethacin; Male; Misoprostol; Pyloric Antrum; Rabbits; Ranitidine; Stomach Ulcer

1993
Arthrotec for all?
    Annals of the rheumatic diseases, 1993, Volume: 52, Issue:12

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Combinations; Female; Humans; Misoprostol; Osteoarthritis; Peptic Ulcer

1993
Protection of the gastroduodenal mucosa from the effects of diclofenac sodium: role of highly selective vagotomy and misoprostol.
    World journal of surgery, 1996, Volume: 20, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Combined Modality Therapy; Diclofenac; Dogs; Duodenum; Female; Gastric Acidity Determination; Gastric Mucosa; Injections, Intramuscular; Intestinal Mucosa; Male; Misoprostol; Peptic Ulcer; Treatment Outcome; Vagotomy, Proximal Gastric

1996
Effects of luteal phase administration of mifepristone (RU486) and prostaglandin analogue or inhibitor on endometrium in the rhesus monkey.
    Human reproduction (Oxford, England), 1998, Volume: 13, Issue:4

    Topics: Animals; Contraceptives, Oral, Synthetic; Cyclooxygenase Inhibitors; Diclofenac; Drug Combinations; Endometrium; Female; Luteal Phase; Macaca mulatta; Male; Mifepristone; Misoprostol

1998
Antinidatory effect of luteal phase administration of mifepristone (RU486) is associated with changes in endometrial prostaglandins during the implantation window.
    Contraception, 1998, Volume: 58, Issue:2

    Topics: Animals; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Embryo Implantation; Endometrium; Female; Hydroxyprostaglandin Dehydrogenases; Luteal Phase; Luteolytic Agents; Macaca mulatta; Male; Mifepristone; Misoprostol; Oxytocics; Prostaglandin-Endoperoxide Synthases; Prostaglandins

1998
Cyclooxygenase inhibitors increase Na-K-2Cl cotransporter abundance in thick ascending limb of Henle's loop.
    The American journal of physiology, 1999, Volume: 277, Issue:2

    Topics: Animals; Carrier Proteins; Cyclooxygenase Inhibitors; Diclofenac; Indomethacin; Loop of Henle; Male; Misoprostol; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Sodium-Potassium-Chloride Symporters

1999
Cost effectiveness of replacing diclofenac with a fixed combination of misoprostol and diclofenac in patients with rheumatoid arthritis.
    Arthritis and rheumatism, 1999, Volume: 42, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Cost-Benefit Analysis; Diclofenac; Drug Therapy, Combination; Female; Gastric Mucosa; Health Status; Humans; Misoprostol

1999
[Arthrotec treatment of rheumatoid arthritis].
    Terapevticheskii arkhiv, 2000, Volume: 72, Issue:1

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Drug Combinations; Endoscopy, Digestive System; Female; Gastric Mucosa; Humans; Middle Aged; Misoprostol; Treatment Outcome

2000
Recurrence of Arthrotec-associated nephrotic syndrome with re-challenge.
    Clinical nephrology, 2000, Volume: 53, Issue:6

    Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Combinations; Humans; Male; Middle Aged; Misoprostol; Nephrotic Syndrome; Osteoarthritis; Recurrence

2000
[Economic evaluation of the use of diclofenac/misoprostol in the treatment of osteoarticular diseases].
    Anales de medicina interna (Madrid, Spain : 1984), 2000, Volume: 17, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Cost-Benefit Analysis; Decision Trees; Diclofenac; Gastrointestinal Diseases; Humans; Misoprostol; Omeprazole; Osteoarthritis; Ranitidine

2000
The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection.
    The Journal of clinical investigation, 2001, Volume: 107, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Capsaicin; Diclofenac; Duodenum; Gastric Mucins; Male; Misoprostol; Neurokinin A; Oligopeptides; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Receptor, PAR-2; Receptors, Thrombin; Saliva; Stomach; Substance P

2001
Gastrointestinal-related healthcare resource usage associated with a fixed combination of diclofenac and misoprostol versus other NSAIDs.
    PharmacoEconomics, 2001, Volume: 19, Issue:5 Pt 2

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Health Resources; Humans; Logistic Models; Male; Misoprostol; Quebec

2001
Are NSAIDs more effective than acetaminophen in patients with osteoarthritis?
    The Journal of family practice, 2001, Volume: 50, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cross-Over Studies; Diclofenac; Double-Blind Method; Drug Combinations; Humans; Misoprostol; Osteoarthritis, Hip; Osteoarthritis, Knee; Randomized Controlled Trials as Topic; Reproducibility of Results

2001
Tragedy and insomnia.
    The New England journal of medicine, 2001, Dec-20, Volume: 345, Issue:25

    Topics: Acute Disease; Anti-Anxiety Agents; Behavior Therapy; Benzodiazepines; Chronic Disease; Diclofenac; Disasters; Drug Combinations; Humans; Hypnotics and Sedatives; Life Change Events; Misoprostol; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Stress, Psychological; Terrorism; United States

2001
Anaphylactoid reaction to a cyclooxygenase-2 inhibitor in a patient who had a reaction to a cyclooxygenase-1 inhibitor.
    The New England journal of medicine, 2001, Dec-20, Volume: 345, Issue:25

    Topics: Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Combinations; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Misoprostol; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Sulfones

2001
[Impact of the education of a patient with arthrosis].
    La Revue du praticien, 2002, Mar-01, Volume: 52, Issue:5 Suppl

    Topics: Aged; Aged, 80 and over; Cyclooxygenase Inhibitors; Diclofenac; Drug Therapy, Combination; Exercise Therapy; Follow-Up Studies; Humans; Middle Aged; Misoprostol; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Patient Education as Topic; Placebos; Randomized Controlled Trials as Topic; Time Factors

2002
Observational study of upper gastrointestinal haemorrhage in elderly patients given selective cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs.
    BMJ (Clinical research ed.), 2002, Sep-21, Volume: 325, Issue:7365

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cohort Studies; Cyclooxygenase 2; Diclofenac; Drug Combinations; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Hospitalization; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Misoprostol; Multivariate Analysis; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Risk Factors; Sulfonamides; Sulfones

2002
[Anaphylactic shock and myocytic necrosis after treatment with Artotec].
    Archives des maladies du coeur et des vaisseaux, 2002, Volume: 95, Issue:12

    Topics: Aged; Anaphylaxis; Anti-Ulcer Agents; Diclofenac; Humans; Male; Misoprostol; Myocardium; Necrosis

2002
A population based historical cohort study of the mortality associated with nabumetone, Arthrotec, diclofenac, and naproxen.
    The Journal of rheumatology, 2004, Volume: 31, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cause of Death; Chronic Disease; Cohort Studies; Diclofenac; Drug Combinations; Female; Humans; Logistic Models; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Risk; Saskatchewan; Survival Rate

2004
Risk of hospitalization with peptic ulcer disease or gastrointestinal hemorrhage associated with nabumetone, Arthrotec, diclofenac, and naproxen in a population based cohort study.
    The Journal of rheumatology, 2005, Volume: 32, Issue:11

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cohort Studies; Databases, Factual; Diclofenac; Drug Combinations; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Male; Middle Aged; Misoprostol; Nabumetone; Naproxen; Peptic Ulcer; Risk Factors; Saskatchewan

2005
Comparison of antinociceptive efficacy and gastroprotection between celecoxib and diclofenac plus misoprostol in rats.
    Proceedings of the Western Pharmacology Society, 2007, Volume: 50

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Combinations; Female; Formaldehyde; Gastric Mucosa; Misoprostol; Pain Measurement; Pyrazoles; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides

2007
Capsule endoscopy and nonsteroidal anti-inflammatory drugs (NSAID)-induced enteropathy--a bit of light in a long, dark tunel.
    Revista espanola de enfermedades digestivas, 2010, Volume: 102, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Intestinal Mucosa; Misoprostol; Osteoarthritis; Peptic Ulcer; Peptic Ulcer Hemorrhage; Severity of Illness Index

2010
[Unilateral odynophagia in rheumatoid arthritis].
    Laryngo- rhino- otologie, 2011, Volume: 90, Issue:8

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cooperative Behavior; Deglutition Disorders; Diagnosis, Differential; Diclofenac; Drug Therapy, Combination; Dysphonia; Endoscopy; Female; Folic Acid; Humans; Interdisciplinary Communication; Lymphopenia; Methotrexate; Middle Aged; Misoprostol; Opportunistic Infections; Oral Ulcer; Pain; Pharyngitis; Prednisolone

2011
Intestinal absorption of lysozyme, an egg-white allergen, in rats: kinetics and effect of NSAIDs.
    Biochemical and biophysical research communications, 2013, Aug-16, Volume: 438, Issue:1

    Topics: Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Drug Interactions; Egg Proteins; Intestinal Absorption; Male; Metabolic Clearance Rate; Misoprostol; Muramidase; Rats; Rats, Sprague-Dawley

2013
Mucosal protective agents prevent exacerbation of NSAID-induced small intestinal lesions caused by antisecretory drugs in rats.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 348, Issue:2

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Dose-Response Relationship, Drug; Gastric Mucins; Gastrointestinal Agents; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Misoprostol; Mucus; Omeprazole; Protective Agents; Proton Pump Inhibitors; Quinolones; Ranitidine; Rats; Rats, Wistar; Sus scrofa; Triazines

2014
Introduction of a manual vacuum aspiration service: a model of service within a NHS Sexual Health Service.
    The journal of family planning and reproductive health care, 2015, Volume: 41, Issue:1

    Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Cost-Benefit Analysis; Diclofenac; Female; Humans; Intrauterine Devices; Misoprostol; Outpatients; Patient Satisfaction; Pregnancy; Reproductive Health; Safety; Self Administration; State Medicine; Vacuum Curettage

2015
Abortion after deliberate Arthrotec® addition to food. Mass spectrometric detection of diclofenac, misoprostol acid, and their urinary metabolites.
    International journal of legal medicine, 2015, Volume: 129, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Chromatography, Liquid; Crime; Diclofenac; Fathers; Female; Food Contamination; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Germany; Humans; Male; Misoprostol; Pregnancy; Pregnancy, Unwanted; Vomiting

2015
Diclofenac/misoprostol during early pregnancy and the risk of miscarriage: a Danish nationwide cohort study.
    Archives of gynecology and obstetrics, 2016, Volume: 294, Issue:2

    Topics: Abortion, Induced; Abortion, Spontaneous; Adult; Cohort Studies; Denmark; Diclofenac; Female; Humans; Misoprostol; Pregnancy; Pregnancy Trimester, First; Proportional Hazards Models; Registries; Retrospective Studies; Risk Factors; Young Adult

2016
Oxytocin and Misoprostol With Diclofenac in the Preparation for Magnetic Resonance-Guided High-Intensity Ultrasound Treatment of Symptomatic Uterine Fibroids: A Prospective Cohort Study.
    Ultrasound in medicine & biology, 2021, Volume: 47, Issue:6

    Topics: Adult; Cohort Studies; Combined Modality Therapy; Diclofenac; Drug Combinations; Female; High-Intensity Focused Ultrasound Ablation; Humans; Leiomyoma; Magnetic Resonance Imaging, Interventional; Misoprostol; Oxytocin; Preoperative Period; Prospective Studies; Surgery, Computer-Assisted; Uterine Neoplasms; Young Adult

2021
Reduced risk of NSAID-Induced adverse events with concomitant use of misoprostol (MICRO study).
    Pharmacotherapy, 2022, Volume: 42, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Misoprostol; Pain; Proportional Hazards Models

2022