diclofenac and methylcellulose

diclofenac has been researched along with methylcellulose in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (15.00)	18.2507
2000's	17 (42.50)	29.6817
2010's	17 (42.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, SC; Kao, YH; Liu, CH; Sheu, MT; Sokoloski, TD	1
Bowtell, R; Davies, MC; Mansfield, P; Melia, CD; Peters, A; Rajabi-Siahboomi, AR; Sharp, JC	1
Ford, JL; Rajabi-Siahboomi, AR; Rowe, P; Velasco, MV	1
Fang, CL; Fang, JY; Lin, HH; Sung, KC	1
Ford, JL; McCrystal, CB; Rajabi-Siahboomi, AR	2
Ford, JL; Rajabi-Siahboomi, AR; Rubinstein, MH; Sadeghi, F	2
Bettini, R; Catellani, PL; Colombo, P; Massimo, G; Peppas, NA; Santi, P	1
Chouinard, F; Lenaerts, V; Leroux, JC; Nekka, F; Rahmouni, M	1
Craig, DQ; Ford, JL; He, R; McCrystal, CB; Rajabi-Siahboomi, AR	1
Dam-Johansen, K; Kiil, S	1
Corrigan, OI; Gubbins, RH; O'Driscoll, CM	1
Gupta, VK; Hariharan, M; Nkansah, P; Wowchuk, C	1
Işimer, A; Ozkan, Y; Savaşer, A	1
Pongjanyakul, T; Priprem, A; Puttipipatkhachorn, S	1
Kazarian, SG; van der Weerd, J	1
Kosmidis, K; Macheras, P; Papadopoulou, V; Vlachou, M	1
Gong, W; Li, B; Zheng, C; Zhu, J	1
Avachat, A; Kotwal, V	1
Anju, P; Kushtagi, P; Manoj, K; Mutalik, S; Ranjith, AK; Reddy, MS; Udupa, N; Usha, AN	1
Antal, I; Auner, A; Csóka, G; Fenyvesi, Z; Gyires, K; Klebovich, I; Marton, S; Pásztor, E; Schmalz, D	1
Chakraborty, S; Khandai, M; Patra, ChN; Patro, VJ; Sen, KK; Sharma, A	1
Bresolin, TM; da Silva, C; Mourão, SC; Porta, V; Serra, CH	1
Drefko, W; Moroni, A; Thone, G	1
Griffiths, PC; Melia, CD; Pygall, SR; Timmins, P; Wolf, B	1
Dua, K; Pabreja, K; Ramana, MV	1
Bhalekar, MR; Godbole, VP; Jagdale, PK; Kshirsagar, SJ; Mohapatra, SK; Shewale, NS	1
Khan, GM; Rehman, A; Shah, KU; Shah, SU	1
Bajerová, M; Dvořáčková, K; Gajdziok, J; Krejčová, K; Masteiková, R; Muselík, J; Rabišková, M	1
Lamberti, G	1
Baumgartner, S; Devjak Novak, S; Šporar, E; Vrečer, F	1
Chakraborty, S; Chandra, A; Ghosal, K; Nanda, A; Rajabalaya, R	1
Dey, S; Gupta, SD; Khila, S; Mahanti, B; Mazumder, B	1
Benaouda, F; Brown, MB; Jones, SA; Martin, GP	1
Boateng, JS; Pawar, HV; Tetteh, J	1
Ahmad, L; Dayoo, A; Iqbal, Z; Khan, A; Khan, JA; Khuda, F; Nasir, F	1
Badr, RM; Emara, LH; Mursi, NM; Taha, NF	1
Catalán-Latorre, A; Díez-Sales, O; El-Sousi, S; Merino, V; Merino-Sanjuán, M; Mura, C; Nácher, A	1
Afrooz, H; Ali, SFB; Bhattacharya, R; Cook, P; Hampel, R; Khan, MA; Mohamed, EM; Rahman, Z	1

Trials

2 trial(s) available for diclofenac and methylcellulose

Article	Year
In-vitro and in-vivo studies of the diclofenac sodium controlled-release matrix tablets. The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:5 Topics: Adult; Chromatography, High Pressure Liquid; Cross-Over Studies; Delayed-Action Preparations; Diclofenac; Hardness; Humans; Lactose; Male; Methylcellulose; Oxazines; Solubility; Tablets	1995
Chitosan and enteric polymer based once daily sustained release tablets of aceclofenac: in vitro and in vivo studies. AAPS PharmSciTech, 2008, Volume: 9, Issue:2 Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Cellulose; Chemistry, Pharmaceutical; Chitosan; Cross-Over Studies; Delayed-Action Preparations; Diclofenac; Double-Blind Method; Drug Administration Schedule; Drug Carriers; Drug Compounding; Drug Stability; Humans; Hydrogen-Ion Concentration; Methylcellulose; Microscopy, Electron, Scanning; Solubility; Spectrophotometry, Infrared; Surface Properties; Tablets, Enteric-Coated; Technology, Pharmaceutical; Therapeutic Equivalency	2008

Article

Year

In-vitro and in-vivo studies of the diclofenac sodium controlled-release matrix tablets.

The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:5

Topics: Adult; Chromatography, High Pressure Liquid; Cross-Over Studies; Delayed-Action Preparations; Diclofenac; Hardness; Humans; Lactose; Male; Methylcellulose; Oxazines; Solubility; Tablets

1995

Chitosan and enteric polymer based once daily sustained release tablets of aceclofenac: in vitro and in vivo studies.

AAPS PharmSciTech, 2008, Volume: 9, Issue:2

Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Cellulose; Chemistry, Pharmaceutical; Chitosan; Cross-Over Studies; Delayed-Action Preparations; Diclofenac; Double-Blind Method; Drug Administration Schedule; Drug Carriers; Drug Compounding; Drug Stability; Humans; Hydrogen-Ion Concentration; Methylcellulose; Microscopy, Electron, Scanning; Solubility; Spectrophotometry, Infrared; Surface Properties; Tablets, Enteric-Coated; Technology, Pharmaceutical; Therapeutic Equivalency

2008

Other Studies

38 other study(ies) available for diclofenac and methylcellulose

Article	Year
NMR microscopy of hydrating hydrophilic matrix pharmaceutical tablets. Magnetic resonance imaging, 1994, Volume: 12, Issue:2 Topics: Diclofenac; Gels; Lactose; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Methylcellulose; Oxazines; Tablets	1994
Influence of drug:hydroxypropylmethylcellulose ratio, drug and polymer particle size and compression force on the release of diclofenac sodium from HPMC tablets. Journal of controlled release : official journal of the Controlled Release Society, 1999, Jan-04, Volume: 57, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Drug Compounding; Hardness Tests; Hypromellose Derivatives; Methylcellulose; Particle Size; Polymers; Pressure; Solubility; Tablets	1999
Transdermal iontophoretic delivery of diclofenac sodium from various polymer formulations: in vitro and in vivo studies. International journal of pharmaceutics, 1999, Feb-01, Volume: 178, Issue:1 Topics: Administration, Cutaneous; Anesthesia; Animals; Cellulose; Chemistry, Pharmaceutical; Diclofenac; Drug Interactions; Humans; In Vitro Techniques; Iontophoresis; Lactose; Male; Methylcellulose; Microdialysis; Oxazines; Polymers; Povidone; Rats; Rats, Wistar; Zingiberales	1999
Water distribution studies within cellulose ethers using differential scanning calorimetry. 1. Effect of polymer molecular weight and drug addition. Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:8 Topics: Calorimetry, Differential Scanning; Cellulose; Diclofenac; Differential Thermal Analysis; Ethers; Gels; Lactose; Methylcellulose; Molecular Weight; Oxazines; Pharmaceutical Preparations; Propranolol; Thermodynamics; Water	1999
Water distribution studies within cellulose ethers using differential scanning calorimetry. 2. Effect of polymer substitution type and drug addition. Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:8 Topics: Calorimetry, Differential Scanning; Cellulose; Diclofenac; Differential Thermal Analysis; Ethers; Gels; Lactose; Methylcellulose; Molecular Weight; Oxazines; Pharmaceutical Preparations; Propranolol; Thermodynamics; Water	1999
Comparative study of drug release from pellets coated with HPMC or Surelease. Drug development and industrial pharmacy, 2000, Volume: 26, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Drug Compounding; Lactose; Methylcellulose; Oxazines; Solubility; Water	2000
Translocation of drug particles in HPMC matrix gel layer: effect of drug solubility and influence on release rate. Journal of controlled release : official journal of the Controlled Release Society, 2001, Feb-23, Volume: 70, Issue:3 Topics: Diclofenac; Drug Delivery Systems; Gels; Lactose; Methylcellulose; Nitrofurantoin; Oxazines; Pyrrolidines; Solubility	2001
Enzymatic degradation of cross-linked high amylose starch tablets and its effect on in vitro release of sodium diclofenac. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2001, Volume: 51, Issue:3 Topics: alpha-Amylases; Amylose; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Enzyme Stability; Gastric Acid; Hydrogen-Ion Concentration; Hydrolysis; Hypromellose Derivatives; Methylcellulose; Models, Biological; Osmolar Concentration; Polyvinyl Alcohol; Pressure; Tablets; Time	2001
Study of drug release from pellets coated with Surelease containing hydroxypropylmethylcellulose. Drug development and industrial pharmacy, 2001, Volume: 27, Issue:5 Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Delayed-Action Preparations; Diclofenac; Dopamine Antagonists; Drug Delivery Systems; Drug Design; Lactose; Methylcellulose; Metoclopramide; Oxazines; Permeability; Sclerosing Solutions	2001
Characterisation of water behaviour in cellulose ether polymers using low frequency dielectric spectroscopy. International journal of pharmaceutics, 2002, Aug-28, Volume: 243, Issue:1-2 Topics: Cellulose; Diclofenac; Electric Conductivity; Gels; Methylcellulose; Molecular Weight; Polymers; Propranolol; Spectrum Analysis; Temperature; Water	2002
Controlled drug delivery from swellable hydroxypropylmethylcellulose matrices: model-based analysis of observed radial front movements. Journal of controlled release : official journal of the Controlled Release Society, 2003, Jun-05, Volume: 90, Issue:1 Topics: Chemical Phenomena; Chemistry, Physical; Delayed-Action Preparations; Diclofenac; Drug Carriers; Hypromellose Derivatives; Mathematics; Methylcellulose; Models, Chemical; Sensitivity and Specificity; Time Factors	2003
The effects of casein on diclofenac release from hydroxypropylmethylcellulose (HPMC) compacts. International journal of pharmaceutics, 2003, Jul-09, Volume: 260, Issue:1 Topics: Caseins; Diclofenac; Excipients; Hypromellose Derivatives; Methylcellulose; Molecular Weight; Solubility; Water	2003
Effect of formulation composition on the properties of controlled release tablets prepared by roller compaction. Drug development and industrial pharmacy, 2004, Volume: 30, Issue:6 Topics: Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Excipients; Fatty Acids; Hypromellose Derivatives; Methylcellulose; Models, Chemical; Particle Size; Solubility; Tablets; Technology, Pharmaceutical; Time Factors	2004
Preparation and in vitro evaluation of sustained release tablet formulations of diclofenac sodium. Farmaco (Societa chimica italiana : 1989), 2005, Volume: 60, Issue:2 Topics: Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Diclofenac; Hydrogen-Ion Concentration; Methylcellulose; Reproducibility of Results; Solubility; Tablets	2005
Influence of magnesium aluminium silicate on rheological, release and permeation characteristics of diclofenac sodium aqueous gels in-vitro. The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:4 Topics: Alginates; Aluminum Compounds; Animals; Chemistry, Pharmaceutical; Diclofenac; Elapidae; Gels; Glucuronic Acid; Hexuronic Acids; Hypromellose Derivatives; In Vitro Techniques; Magnesium Compounds; Methylcellulose; Poloxamer; Rheology; Silicates; Skin Absorption; Time Factors; Viscosity	2005
Release of poorly soluble drugs from HPMC tablets studied by FTIR imaging and flow-through dissolution tests. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Hydrogen-Ion Concentration; Hypromellose Derivatives; Least-Squares Analysis; Methylcellulose; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Time Factors; Water	2005
On the use of the Weibull function for the discernment of drug release mechanisms. International journal of pharmaceutics, 2006, Feb-17, Volume: 309, Issue:1-2 Topics: Delayed-Action Preparations; Diclofenac; Diffusion; Diltiazem; Hypromellose Derivatives; Kinetics; Methylcellulose; Models, Chemical; Polymers; Solubility; Tablets	2006
A novel system for three-pulse drug release based on "tablets in capsule" device. International journal of pharmaceutics, 2008, Mar-20, Volume: 352, Issue:1-2 Topics: Alginates; Capsules; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Drug Carriers; Drug Compounding; Excipients; Glucuronic Acid; Hardness; Hexuronic Acids; Hypromellose Derivatives; Kinetics; Lactose; Methylcellulose; Sodium Chloride; Solubility; Tablets; Technology, Pharmaceutical	2008
Design and evaluation of matrix-based controlled release tablets of diclofenac sodium and chondroitin sulphate. AAPS PharmSciTech, 2007, Oct-19, Volume: 8, Issue:4 Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Chondroitin Sulfates; Delayed-Action Preparations; Diclofenac; Drug Carriers; Drug Combinations; Drug Compounding; Hypromellose Derivatives; Kinetics; Methylcellulose; Models, Chemical; Solubility; Technology, Pharmaceutical; Water	2007
Preparation of pH-sensitive beads for NSAID using three-component gel systems. Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:11 Topics: Alginates; Anti-Inflammatory Agents, Non-Steroidal; Crystallization; Diclofenac; Dosage Forms; Drug Delivery Systems; Gels; Hydrogen-Ion Concentration; Hypromellose Derivatives; Methylcellulose; Microspheres; Particle Size; Solubility; Technology, Pharmaceutical	2009
Effects of drug solubility on the release kinetics of water soluble and insoluble drugs from HPMC based matrix formulations. Acta pharmaceutica (Zagreb, Croatia), 2009, Volume: 59, Issue:3 Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Hypromellose Derivatives; Methylcellulose; Solubility; Tablets; Verapamil; Water	2009
Dissolution parameters for sodium diclofenac-containing hypromellose matrix tablet. International journal of pharmaceutics, 2010, Feb-15, Volume: 386, Issue:1-2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Buffers; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Drug Carriers; Hardness; Hydrogen-Ion Concentration; Hypromellose Derivatives; Kinetics; Methylcellulose; Models, Chemical; Solubility; Tablets; Technology, Pharmaceutical; Temperature	2010
Formulations of zero-order, pH-dependent, sustained release matrix systems by ionotropic gelation of alginate-containing mixtures. Drug development and industrial pharmacy, 2011, Volume: 37, Issue:2 Topics: Alginates; Calcium; Delayed-Action Preparations; Diclofenac; Drug Stability; Excipients; Gels; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Hypromellose Derivatives; Methylcellulose; Polysaccharides, Bacterial; Propranolol; Solubility; Tablets; Theophylline; Time Factors	2011
Solution interactions of diclofenac sodium and meclofenamic acid sodium with hydroxypropyl methylcellulose (HPMC). International journal of pharmaceutics, 2011, Feb-28, Volume: 405, Issue:1-2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Hypromellose Derivatives; Meclofenamic Acid; Methylcellulose; Pharmaceutical Solutions; Solubility; Specific Gravity; Surface Tension; Transition Temperature; Viscosity	2011
Aceclofenac topical dosage forms: in vitro and in vivo characterization. Acta pharmaceutica (Zagreb, Croatia), 2010, Volume: 60, Issue:4 Topics: Acrylic Resins; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Edema; Gels; Hyperalgesia; Hypromellose Derivatives; Inflammation; Male; Methylcellulose; Ointments; Polyethylene Glycols; Rabbits; Rats; Rats, Wistar; Skin Irritancy Tests; Solubility	2010
Development of enzyme-controlled colonic drug delivery using amylose and hydroxypropyl methylcellulose: optimization by factorial design. Drug delivery, 2011, Volume: 18, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Amylose; Chemistry, Pharmaceutical; Colon; Diclofenac; Drug Delivery Systems; Humans; Hydrogen-Ion Concentration; Hypromellose Derivatives; Male; Methylcellulose; Middle Aged; Pharmaceutical Preparations; Tablets; Young Adult	2011
Investigating the in vitro drug release kinetics from controlled release diclofenac potassium-ethocel matrix tablets and the influence of co-excipients on drug release patterns. Pakistan journal of pharmaceutical sciences, 2011, Volume: 24, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Carboxymethylcellulose Sodium; Cellulose; Diclofenac; Excipients; Hypromellose Derivatives; Methylcellulose; Solubility; Tablets	2011
Oxycellulose beads with drug exhibiting pH-dependent solubility. AAPS PharmSciTech, 2011, Volume: 12, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Buffers; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Diffusion; Drug Carriers; Drug Compounding; Feasibility Studies; Gastric Juice; Hydrogen-Ion Concentration; Hypromellose Derivatives; Kinetics; Methylcellulose; Models, Chemical; Particle Size; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical	2011
Parametric simulation of drug release from hydrogel-based matrices. The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Drug Carriers; Hydrogel, Polyethylene Glycol Dimethacrylate; Hypromellose Derivatives; Methylcellulose; Models, Theoretical; Pharmaceutical Preparations	2012
Characterization of physicochemical properties of hydroxypropyl methylcellulose (HPMC) type 2208 and their influence on prolonged drug release from matrix tablets. Journal of pharmaceutical and biomedical analysis, 2012, Volume: 66 Topics: Calibration; Chromatography, Gas; Diclofenac; Drug Compounding; Excipients; Hypromellose Derivatives; Methylcellulose; Microscopy, Electron, Scanning; Molecular Weight; Particle Size; Solubility; Spectroscopy, Near-Infrared; Tablets	2012
Mathematical modeling of drug release profiles for modified hydrophobic HPMC based gels. Die Pharmazie, 2012, Volume: 67, Issue:2 Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Computer Simulation; Delayed-Action Preparations; Diclofenac; Gels; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Kinetics; Logistic Models; Methylcellulose; Models, Statistical; Nonlinear Dynamics; Pharmaceutical Preparations; Software; Solubility; Viscosity	2012
Formulation development and optimization of bilayer tablets of aceclofenac. Expert opinion on drug delivery, 2012, Volume: 9, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Drug Delivery Systems; Lactose; Methylcellulose; Solubility; Tablets	2012
Triggered in situ drug supersaturation and hydrophilic matrix self-assembly. Pharmaceutical research, 2012, Volume: 29, Issue:12 Topics: Anti-Inflammatory Agents, Non-Steroidal; Crystallization; Diclofenac; Ethanol; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Methylcellulose; Propylene Glycol; Solubility; Thermodynamics	2012
Preparation, optimisation and characterisation of novel wound healing film dressings loaded with streptomycin and diclofenac. Colloids and surfaces. B, Biointerfaces, 2013, Feb-01, Volume: 102 Topics: Adipates; Calorimetry, Differential Scanning; Carrageenan; Chitosan; Diclofenac; Hypromellose Derivatives; Methylcellulose; Microscopy, Electron, Scanning; Polymers; Spectroscopy, Fourier Transform Infrared; Streptomycin; X-Ray Diffraction	2013
Development and evaluation of diclofenac sodium thermorevesible subcutaneous drug delivery system. International journal of pharmaceutics, 2012, Dec-15, Volume: 439, Issue:1-2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Delivery Systems; Gels; Hypromellose Derivatives; Injections, Subcutaneous; Male; Methylcellulose; Poloxamer; Polyethylene Glycols; Rabbits; Temperature	2012
Development of an osmotic pump system for controlled delivery of diclofenac sodium. Drug discoveries & therapeutics, 2012, Volume: 6, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Excipients; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Kinetics; Lactose; Membranes, Artificial; Methylcellulose; Microscopy, Electron, Scanning; Osmosis; Plasticizers; Polyethylene Glycols; Porosity; Potassium Chloride; Sodium Chloride; Solubility; Surface Properties; Tablets; Technology, Pharmaceutical; Triacetin	2012
Hydroxypropylmethylcellulose films for the ophthalmic delivery of diclofenac sodium. The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:2 Topics: Administration, Ophthalmic; Anti-Inflammatory Agents, Non-Steroidal; Chitosan; Diclofenac; Dosage Forms; Drug Delivery Systems; Hyaluronic Acid; Hypromellose Derivatives; Methylcellulose; Nanoparticles; Permeability; Polymers	2013
Blend of cellulose ester and enteric polymers for delayed and enteric coating of core tablets of hydrophilic and hydrophobic drugs. International journal of pharmaceutics, 2019, Aug-15, Volume: 567 Topics: Cellulose; Diclofenac; Drug Liberation; Hydrophobic and Hydrophilic Interactions; Methylcellulose; Polymethacrylic Acids; Prednisone; Tablets, Enteric-Coated	2019