diclofenac has been researched along with ibuprofen in 591 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (8.46) | 18.7374 |
| 1990's | 60 (10.15) | 18.2507 |
| 2000's | 165 (27.92) | 29.6817 |
| 2010's | 245 (41.46) | 24.3611 |
| 2020's | 71 (12.01) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Boettcher, I; Elger, W; Kirsch, G; Siegmund, F; Wachtel, H | 1 |
| Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S | 1 |
| Cha, SH; Endou, H; Kanai, Y; Kim, DK; Kim, JY; Kusuhara, H; Sekine, T; Sugiyama, Y; Yu, E | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Cihlar, T; Ho, ES; Mulato, AS | 1 |
| Faller, B; Wohnsland, F | 1 |
| Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T | 1 |
| Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A | 1 |
| Bain, G; Beher, D; Chen, W; Jiang, X; Munoz, B; Peachey, J; Prasit, P; Shearman, MS; St-Jacques, R; Stock, N; Williamson, TL; Wrigley, JD | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Ho, A; Marotti, KR; Romero, DL; Sarver, RW; Thorarensen, A; Tian, F | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Barreiro, EJ; Fraga, CA; Lima, LM; Romeiro, NC; Sant'Anna, CM | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Kalluraya, B; Rao, JN; Shetty, P; Sujith, KV | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Avdeef, A; Tam, KY | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Horie, T; Horiguchi, A; Kitamura, S; Kotake, Y; Ohshita, H; Ohta, S; Sanoh, S; Sugihara, K; Tateno, C; Tayama, Y | 1 |
| Cabrita, EJ; Corvo, MC; Manso, J; Marques, MM; Viegas, A | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cai, J; Chao, M; Chen, J; Duan, Y; Ji, M; Yu, J | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C | 1 |
| Govardhan Reddy, K; Nagaraju, D; Rajanarendar, E; Ramakrishna, S; Reddy, YN | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Headey, SJ; Hughes, ML; Laguerre, A; Mohanty, B; Patil, R; Porter, CJ; Scanlon, MJ; Wielens, J; Williams, ML | 1 |
| Dalby, KN; Kaoud, TS; Radwan, MF | 1 |
| Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P | 1 |
| Bennis, K; Ducki, S; Lesage, F; Vivier, D | 1 |
| Gavalas, A; Kourti, M; Rekka, EA; Theodosis-Nobelos, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dalvie, D; Fu, Y; Khojasteh, SC; Ma, Y; Zhang, D | 1 |
| Anastácio Furtado Pacheco, P; Arruda, JC; Bello, ML; Castro, HC; da Silva, FC; Dantas, LP; de Freitas, HR; de Melo Reis, RA; Faria, RX; Ferreira, LBG; Ferreira, VF; Gonzaga, DTG; Moreira Maramaldo Costa, TE; Penido, C; Rodrigues, CR; Sposito Simões, AP; von Ranke, NL | 1 |
| Asif, M; Husain, A; Iqbal, MA; Iram, F; Khan, SA | 1 |
| Chung, HY; Hong, J; Ju, Z; Jung, JH; Kim, S; La Kim, E; Moon, HR; Su, M | 1 |
| Bartolucci, G; Bua, S; Carta, F; Di Cesare Mannelli, L; Ghelardini, C; Gratteri, P; Lucarini, L; Masini, E; Menicatti, M; Micheli, L; Nocentini, A; Selleri, S; Supuran, CT | 1 |
| DeRose, EF; Duff, MR; Gabel, SA; Howell, EE; Krahn, JM; London, RE; Pedersen, LC | 1 |
| Neha, K; Wakode, S | 1 |
| Sieberer, W; Siegmeth, W | 1 |
| Kawai, K; Kuzuna, S; Morimoto, S | 1 |
| Dürrigl, T; Pucar, I | 1 |
| Burdeĭnyĭ, AP | 1 |
| Pemberton, RE; Strand, LJ | 1 |
| Gothoni, G; Rejholec, V; Tokola, O; Vapaatalo, H | 1 |
| Motta, C | 1 |
| Bonomo, I | 1 |
| Cardoe, N; Fowler, PD | 1 |
| Ciccolunghi, SN; Reddrop, R; Schubiger, BI | 1 |
| Ohtsuki, H; Okabe, S; Tabata, K | 1 |
| Ikeda, S; Tanaka, M; Uchiyama, M | 1 |
| Blagbrough, IS; Daykin, MM; Doherty, M; Pattrick, M; Shaw, PN | 1 |
| Abe, K; Akiu, N; Saito, T; Sato, M; Takeuchi, K; Yasujima, M; Yoshinaga, K | 1 |
| Denissov, LN; Samsonov, MA; Sharafetdinov, Kh | 1 |
| Bright, TP; McNulty, CJ | 1 |
| Raineri-Gerber, I; von Felten, A | 1 |
| Calin, A; Elswood, J | 1 |
| Noakes, TD; Reinach, SG; Schwellnus, MP; Theunissen, L | 1 |
| Neuvonen, PJ | 1 |
| Blower, PR; Gentry, C; Melarange, R; O'Connell, C | 1 |
| Eberl, R; Partsch, G; Schwarzer, C | 1 |
| Bell, AL; McGalliard, J | 1 |
| Brune, K; Dietzel, K; Nuernberg, B; Schneider, HT | 1 |
| Brune, K; Jurna, I | 1 |
| Czernielewski, J; Duteil, L; Ortonne, JP; Poncet, M; Queille, C | 1 |
| Otto, S | 2 |
| Pavelka, K; Trnavsky, K | 1 |
| Paulus, HE; Schlegel, SI | 1 |
| Bernard, AA; Kersley, JB | 1 |
| Kothari, HV; Ku, EC; Lee, W; Scholer, DW | 1 |
| Sallmann, AR | 2 |
| Zuckner, J | 1 |
| Caldwell, JR | 2 |
| Altman, R | 1 |
| Catalano, MA | 1 |
| Gribnau, FW; Koopmans, PP; Thien, T | 1 |
| DeLong, RE; Phillis, JW; Towner, JK | 1 |
| Bekemeier, H; Schmollack, W; Scholz, U | 1 |
| Blake, JW; Tobin, T; Weckman, T; Woods, WE | 1 |
| Wilson, JT | 1 |
| Willkens, RF | 1 |
| Kimble, EF; Kothari, HV; Ku, EC; Lee, W; Liauw, L; Tjan, J | 1 |
| Kimble, EF; Kothari, H; Ku, EC; Lee, W; Liauw, LH | 1 |
| Jelić-Ivanović, Z; Majkić-Singh, N; Spasić, S; Todorović, P | 1 |
| Catanzaro-Guimarães, SA; de Menezes, MR | 1 |
| Machtey, I | 1 |
| Bryans, R; Huskisson, EC | 1 |
| Famaey, JP; Ginsberg, F | 1 |
| Carlsson, I; Wennmalm, A | 1 |
| Cronberg, S; Söderberg, I; Wallmark, E | 1 |
| Mashiah, V; Yaron, I; Yaron, M | 1 |
| Isomäki, H; Kaarela, K; Kajander, A; Koota, K; Lehtinen, K; Luukkainen, R; Martio, J; Martio, T; Nissilä, M; Nuotio, P | 1 |
| Obel, AO | 1 |
| Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM | 1 |
| Biver, P; Bottone, E; Saggese, G; Terrosi, F | 1 |
| Brooks, PM; Geddes, R; Hill, W | 1 |
| Danneskiold-Samsøe, B; Meinicke, J | 1 |
| Chiswell, RJ; Crook, PR; Fowler, PD; Hothersall, TE | 1 |
| Pathy, MS | 1 |
| Hüge, W; Stobbe, H | 1 |
| Abou-Basha, L; Farag, MM; Salama, MA | 1 |
| Locatelli, L; Mantegazza, P; Panerai, AE; Sacerdote, P | 1 |
| Locatelli, L; Panerai, AE; Sacerdote, P | 1 |
| Kiff, PS; Morant, SV; Shield, MJ; Stead, H | 1 |
| Ford, J; Houston, JB | 1 |
| Arakawa, K; Fujimura, A; Kimoto, N; Kogawara, S; Murata, T; Naito, S; Yoshida, K; Yoshizawa, S | 1 |
| Kajiyama, G; Lane, NE; Smith, RL | 1 |
| Chemtob, S; Hanna, N; Lachapelle, P; Orquin, J; Roy, MS; Varma, DR | 1 |
| Dang, H; Flescher, E; Fossum, D; Ledbetter, JA; Ogawa, N; Talal, N; Vela-Roch, N | 1 |
| Björkman, R | 1 |
| Blower, P; Melarange, R; Spangler, R | 1 |
| Bakshi, R; Dietlein, G; Frenkel, G; Meurer-Witt, B; Schneider, B; Sinterhauf, U | 1 |
| Baeyens, W; Donato, MG; Sandra, P; van den Bossche, W | 1 |
| DeLapp, RE; Eversmeyer, W; Jensen, CP; Poland, M | 1 |
| DeLapp, RE; Morgan, GJ; Poland, M | 1 |
| DeLapp, RE; Lister, BJ; Poland, M | 1 |
| Ahlström, U; Bakshi, R; Nilsson, P; Wåhlander, L | 1 |
| Alfredsson, L; Kaufman, DW; Kelly, JP; Koff, RS; Laszlo, A; Shapiro, S; Sheehan, JE; Wiholm, BE | 1 |
| Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Iizuka, H; Otomo, S; Yoshikawa, K | 1 |
| Bakshi, R; Fedele, L; Marchini, M; Pistai, R; Tozzi, L | 1 |
| Cahill, RJ; Gilvarry, J; O'Morain, CA; Sant, SM | 1 |
| Bairagi, NR; Kessel, E; Mullick, BC; Mumford, SD | 1 |
| Abdel-Meguid, E; Abdel-Tawab, S; Farag, MM; Mikhail, M; Shehata, R | 1 |
| Becker, L; Eberlein-König, B; Przybilla, B | 1 |
| Baumgartner, H; Blum, W; Bruhin, A; Gallachi, G; Goldinger, G; Saxer, M; Schwarz, HA; Trost, H | 1 |
| Björkman, R; Hallman, KM; Hedner, J; Hedner, T; Henning, M | 1 |
| Brenke, B; Nahm, AM; Ritz, E | 1 |
| Brugger, A; Hawel, R; Klein, G; Mitterhuber, J | 1 |
| Caldwell, J; Kenna, JG; Wade, LT | 1 |
| Rømsing, J; Walther-Larsen, S | 1 |
| Caruso, FS; Frenk, H; Lu, J; Mao, J; Mayer, DJ; Price, DD | 1 |
| Dvivedi, S; Sharma, A; Tiwari, SM | 1 |
| Casini, ML; Mattei, E; Panzironi, C; Saso, L; Silvestrini, B; Valentini, G | 1 |
| Gabard, B; Treffel, P | 1 |
| Nagai, T; Príborský, J; Takayama, K | 1 |
| Ghanayem, BI; Goldstein, JA; Hall, SD; Ibeanu, GC; Klose, TS; Li, L; Pedersen, LG | 1 |
| Curti, C; Mingatto, FE; Pigoso, AA; Rodrigues, T; Santos, AC; Uyemura, SA | 1 |
| Frame, J; Hawkesford, JE; Marsden, J; Matthew, IR; Negus, TW; Seymour, RA | 1 |
| McQuay, HJ; Moore, RA | 1 |
| Adcock, S; Bachmann, KA; Chan, CC; Cohen, RA; Davidson, MH; Dobratz, D; Gertz, BJ; Grasing, K; Hedges, J; Jones, TM; McBride, KJ; Moritz, C; Mukhopadhyay, S; Schwartz, JI | 1 |
| Duque-Oliart, A; García-Rodríguez, LA; Pérez-Gutthann, S; Varas-Lorenzo, C | 1 |
| Bolognese, JA; Harper, SE; Jensen, DM; Langman, MJ; Quan, H; Simon, TJ; Watson, DJ; Zhao, PL | 1 |
| Iley, J; Mendes, E; Moreira, R; Souza, S | 1 |
| Cullen , DJ; Doherty, M; Garner, S; Garrud, P; Hawkey, CJ; Holmes, S; Logan, RF; Maynard, A; Seager, JM; Wilson, JV | 1 |
| Cullen, DJ; Doherty, M; Garner, S; Garrud, P; Hawkey, CJ; Holmes, S; Logan, RF; Maynard, A; Pearson, G; Seager, JM; Wilson, JV | 1 |
| Callahan, LF; Cummins, P; Pincus, T; Swearingen, C | 1 |
| Collins, SL; Edwards, JE; McQuay, HJ; Moore, RA; Wiffen, PJ | 1 |
| Agrawal, NM; Burr, AM; Eisen, G; Faich, G; Geis, GS; Goldstein, JL; Kent, JD; Lefkowith, JB; Makuch, R; Pincus, T; Silverstein, FE; Simon, LS; Stenson, WF; Verburg, KM; Whelton, A; Zhao, WW | 1 |
| Arnout, J; Buntinx, A; Dallob, A; De Lepeleire, I; De Schepper, PJ; Depré, M; Ebel, DL; Gertz, BJ; Schwartz, JI; Tanaka, W; Van Hecken, A; Wong, PH; Wynants, K | 1 |
| Tive, L | 1 |
| Abdullah, AS; Al-Hashimi, AH; Jawad, AM | 1 |
| Bujak-Gizycka, B; Kłys, M; Latacz, B; Skupień, E | 1 |
| Bergmann, JF; Caulin, C; Diemer, M; Knellwolf, AL; Mahé, E; Mahé, I; Mouly, S; Simoneau, G | 1 |
| De Los Santos, AR; Di Girolamo, G; Kaminker, AJ; Kramer, EH; Martí, ML; Sassetti, B | 1 |
| Hodgson, DM; Taylor, AN; Yirmiya, R | 1 |
| Browning, RA; Burgess, FW | 1 |
| Schmoldt, A; Tsokos, M | 1 |
| Catella-Lawson, F; Cucchiara, AJ; DeMarco, S; FitzGerald, GA; Kapoor, SC; Reilly, MP; Tournier, B; Vyas, SN | 1 |
| Simon, LS | 1 |
| Barr, E; Reicin, AS; Shapiro, D; Sperling, RS; Yu, Q | 1 |
| Faich, G; Geis, GS; Lefkowith, JB; Maurath, C; Ridge, NJ; Verburg, KM; Whelton, A; White, WB | 1 |
| Blain, H; Boileau, C; Gaucher, A; Guillaume, C; Jeandel, C; Jouzeau, JY; Lapicque, F; Loeuille, D; Nédélec, E; Netter, P | 1 |
| Bhagat, K | 1 |
| Bolognese, JA; Harper, SE; Simon, TJ; Watson, DJ; Zhao, PL | 1 |
| Bolognese, JA; Gertz, BJ; Krupa, D; Reicin, A; Sperling, RS | 1 |
| Downing, SJ; Leese, HJ; Maguiness, SD; Tay, JI; Watson, A | 1 |
| Egyed, A; Fedorocko, P; Hofer, M; Hoferová, Z; Hofmanová, J; Kozubík, A; Minksová, K; Soucek, K; Znojil, V | 1 |
| McCormack, JP; Rangno, R | 1 |
| Geis, GS | 1 |
| Khan, AI; Lei, L; Norquist, AJ; O'Hare, D | 1 |
| Agrawal, NM; Kent, JD; Recker, DP; Sikes, DH; Verburg, KM; Zhao, WW | 1 |
| Pfeifer, M | 1 |
| Lasek, R; Victor, N; Witte, S | 1 |
| Gold, MS; Ionescu, E; Kubitzek, F; Liu, JM; Ziegler, G | 1 |
| Hanzlik, J; Kazubek, M; Mosiewicz, J; Myslinski, W; Pegiel-Sicko, E; Przyszlak-Szabala, M | 1 |
| Frank, WO; Gold, MS; Grebe, W; Ionescu, E; Liu, JM | 1 |
| Frimmel, FH; Zwiener, C | 1 |
| Brooks, G; Crabbe, MJ; Harper, JV; Shattock, MJ; Wang, Y; Yu, XM | 1 |
| Maliarova, LP; Riabkova, AA; Savel'ev, VS; Shostak, NA | 1 |
| Coleman, CN; Palayoor, ST; Tofilon, PJ | 1 |
| Cowan, A; Raffa, RB; Tallarida, RJ | 1 |
| Dreiser, RL; Gold, M; Ionescu, E; Liu, JH; Marty, M | 1 |
| Hughes, LF; Krishna, S; Lin, SY | 1 |
| Harley, C; Wagner, S | 1 |
| Chen, BY; Cheng, NN; Li, D; Shi, W; Wang, YM | 1 |
| Brouwers, JR; de Jong-van den Berg, LT; de Vries-Bots, AM; Piersma-Wichers, M; Plat, AW; Slomp, J; van Dijk, AA; van Dijk, KN | 1 |
| Ahmed, S; Kragh-Hansen, U; Maruyama, T; Otagiri, M; Rahman, MH; Tsutsumi, Y; Yamasaki, K | 1 |
| Aguilar, C; Borrull, F; Calull, M; Macià, A | 1 |
| Davies, C; DeVoss, JJ; Gillam, EM; Graham, SE; Pearson, A; Scott, JR; Witham, K | 1 |
| Bagheri, H; Lacroix, I; Lapeyre-Mestre, M; Montastruc, JL; Pathak, A | 1 |
| Freund, J; Ting, A | 1 |
| Fricke, JR; Jayawardene, S; Kellstein, D; Zelenakas, K | 1 |
| Gotoh, T; Hoshino, T; Hwang, HJ; Mima, S; Mizushima, T; Mori, M; Takenaka, H; Tomisato, W; Tsuchiya, T; Tsutsumi, S | 1 |
| Gimona, A; Hawkey, C; Kivitz, AJ; Nayiager, S; Schimansky, T; Thurston, HJ | 1 |
| García Rodríguez, LA; González-Pérez, A; Maguire, A; Varas-Lorenzo, C | 1 |
| Andersson, TB; Bredberg, E; Ericsson, H; Sjöberg, H | 1 |
| Ehrsam, E; Farkouh, M; Gitton, X; Hawkey, CJ; Huels, J; Richardson, P | 1 |
| Joshi, A; Macfarlane, TV; Parara, E | 1 |
| Abdel-Hafiz, SM; Al-Safi, SA; Albsoul-Younes, AM; Jabateh, SK | 1 |
| Cousin, M; Fiedorowicz-Fabrycy, IF; Gitton, X; Hawkey, CC; Hoexter, G; Nasonov, EL; Pikhlak, EG; Svoboda, P | 1 |
| Bégaud, B; Boisseau, M; Moore, N; Umar, A; Upur, H; Yusup, A | 1 |
| Clara, M; Gans, O; Kreuzinger, N; Strenn, B | 1 |
| Summerton, N | 1 |
| Dahlborg, R; Day, CA; Jacob, RF; Mason, RP; Walter, MF; Weng, Y | 1 |
| Al-Saidan, SM | 1 |
| Morillo, LE | 2 |
| Cadiou, H; Jones, NG; McMahon, SB; McNaughton, P; Slater, R | 1 |
| Hollenz, M; Labenz, J | 1 |
| Foster, GD; Thomas, PM | 1 |
| Berlin, JA; Chittams, J; Jaskowiak, J; Kimmel, SE; Kishel, L; Reilly, M; Strom, BL | 1 |
| Lucas, R; Mitchell, JA; Vojnovic, I; Warner, TD | 1 |
| Giagoudakis, G; Markantonis, SL | 1 |
| Goldstein, JL; Mayne, TJ; Rabeneck, L; Rublee, DA; Vu, A | 1 |
| Ferrer, I; Thurman, EM | 1 |
| Pina, ME; Santos, H; Sousa, JJ; Veiga, F | 1 |
| De Alencastro, LF; Grandjean, D; Tarradellas, J; Tauxe-Wuersch, A | 1 |
| Heberer, T; Lindstädt, R; Mersmann, P; Scheytt, T | 1 |
| Kronberg, L; Lindqvist, N; Tuhkanen, T | 1 |
| Bendz, D; Ginn, TR; Loge, FJ; Paxéus, NA | 1 |
| Quintana, JB; Reemtsma, T; Weiss, S | 1 |
| Alnouti, Y; Bi, H; Gusev, AI; Kavetskaia, O; Srinivasan, K; Waddell, D | 1 |
| Burba, P; Geltenpoth, H; Nolte, J | 1 |
| McCarthy, DM | 1 |
| Meechan, J | 1 |
| Bierma-Zeinstra, SM; Hazes, JM; Koes, BW; Pols, HA; Reijman, M; Stricker, BH | 1 |
| Heberer, T; Mersmann, P; Scheytt, TJ | 1 |
| García Rodríguez, LA; Hernández-Díaz, S; Varas-Lorenzo, C | 1 |
| Blasco, M; Caunedo, A; Esteban, J; Gómez, BJ; Hergueta, P; Herrerías, JM; Pellicer, FJ; Redondo, L; Rodríguez-Téllez, M; Romero, R; Sáenz-Dana, M | 1 |
| Aguilar, I; Aranda Regules, JM; Faus, V; Herrera Galante, A; Martinez Barquin, DM; Mendez, C; Perea-Milla, E; Silva, LC; Vas, J | 1 |
| Biebow, M; Boller, M; Pronk, W | 1 |
| Abildstrom, SZ; Buch, P; Friberg, J; Gislason, GH; Jacobsen, S; Køber, L; Madsen, M; Rasmussen, JN; Rasmussen, S; Schramm, TK; Torp-Pedersen, C | 1 |
| Castellsague, J; Maguire, A; Perez-Gutthann, S; Varas-Lorenzo, C | 1 |
| Lefkowith, JL; Verburg, KM; West, CR; Whelton, A | 1 |
| Brookhart, MA; Rassen, J; Schneeweiss, S; Solomon, DH; Wang, PS | 1 |
| Alvarez-Lorenzo, C; Andrade-Vivero, P; Concheiro, A; Fernandez-Gabriel, E | 1 |
| Kong, SX; LeLorier, J; Rahme, E; Toubouti, Y; Watson, DJ | 1 |
| Berger, MY; Damen, L; Koes, BW; Merlijn, V; Passchier, J; Verhagen, AP | 1 |
| Brümmer, J; Paschke, A; Schüürmann, G | 1 |
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| Brown, C; Corson, S; Crawford, GM; Wade, AG; Young, D | 1 |
| Abed, A; Abu-Shalhoob, M; Jarrar, Q; Jarrar, Y; Sha'ban, E | 1 |
| Aydin, ME; Aydin, S; Ulvi, A | 1 |
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| Back, D; Dos Santos, PR; Dumas, F; Moura, S; Pich, CT; Smiderle, F | 1 |
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| Buckles, TC; Djukovic, D; Falke, JJ; Ziemba, BP | 1 |
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| Parolini, M | 1 |
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| Fadini, PS; Granatto, CF; Grosseli, GM; Sakamoto, IK; Varesche, MBA | 1 |
| Boyd, BJ; Craig, DQM; Goh, CF; Lane, ME | 1 |
| Alves, MM; Gomes, JC; Martins, G; Pereira, L; Salvador, AF; Silva, AR | 1 |
| Hadjmohammadi, MR; Jafari, Z | 1 |
| Aguilar-Romero, I; Romero, E; van Dillewijn, P; Wittich, RM | 1 |
| Glatz, Z; Michalcová, L; Nevídalová, H | 1 |
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| Dilmaghani, A; Eyvazi, S; Tarhriz, V; Yousefi, V | 1 |
| Chen, Z; Hu, B; Hu, S; Vymazal, J | 2 |
| Allen, IE; Auerbach, A; Bongiovanni, T; Lancaster, E; Ledesma, Y; Steinman, MA; Whitaker, E; Wick, E | 1 |
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| Dotto, GL; Foletto, EL; Leichtweis, J; Mistura, CM; Oliveira, LFS; Pereira, HA; Vieira, Y | 1 |
| Allam, B; Choi, KS; Kim, SH; Nam, KW; Park, KH; Park, KI | 1 |
| Cush, I; Pennick, G; Robinson-Miller, A | 1 |
| Cortijo-Brown, A; Davitt, M; Feliciano, C; Friedman, BW; Irizarry, E; Restivo, A; Salama, M | 1 |
| Caban, M; Kumirska, J; Mulkiewicz, E; Stepnowski, P; Świacka, K; Wolecki, D | 1 |
| Abdel-Hafez, AA; Abdellatif, AAH; Agabein, EM; Al-Omar, MS; Alqasoomi, I; Alrashidi, SA; Eltom, SEM; Maswadeh, H; Mobark, MA; Mohammed, HA; Sajid, MSM | 1 |
| Davies, GL; Duan, H; Harman, CLG; Strimaite, M; Wang, Y; Williams, GR | 1 |
| Ahmed, F; Li, J; Mueller, JF; O'Brien, JW; Samanipour, S; Thai, PK; Thomas, KV; Tscharke, BJ; Yuan, Z | 1 |
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| Carmona, Z; Gutierrez-Suarez, K; Moreno Ríos, AL; Ramos, CG; Silva Oliveira, LF | 1 |
| Hassanzadeh, H; Mischak, I; Payer, M; Sandner-Kiesling, A; Schanbacher, M; Sendlhofer, G; Tomic, J; Wallner, J; Zemann, W; Zrnc, TA | 1 |
| Díaz de León-Martínez, L; Flores-Ramírez, R; Galván-Romero, V; Medellín-Castillo, NA; Meléndez-Marmolejo, J; Ocampo-Pérez, R; Padilla-Ortega, E; Rodríguez-Torres, I; Villarreal-Lucio, S | 1 |
| Aguilar-Romero, I; Delgado-Moreno, L; Nesme, J; Nogales, R; Romero, E; Sørensen, SJ; van Dillewijn, P | 1 |
| Björklund, E; Jankowska, K; Lambropoulou, D; Luczkiewicz, A; Nannou, C; Polkowska, Ż; Potapowicz, J; Svahn, O; Szopińska, M | 1 |
| Kumpangnil, K; Leksomboon, R; Pangjit, K; Udomsuk, L | 1 |
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| Ikushiro, S; Iwai, Y; Nishikawa, M; Sakaki, T; Sugimoto, H; Takita, T; Yasuda, K; Yasukawa, K; Yogo, Y | 1 |
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| Alatawi, H; Albalawi, I; Alsefri, S; Hogan, A; Moore, E; O'Sullivan-Carroll, E; Wang, Y | 1 |
| Blahova, J; Crhanova, M; Faldyna, M; Franc, A; Hodkovicova, N; Hollerova, A; Karasova, D; Lanikova, J; Mares, J; Marsalek, P; Mikula, P; Pavlokova, S; Postulkova, E; Svobodova, Z; Tichy, F | 1 |
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| Bila, DM; da Fonseca, EM; da Silva de Freitas, A; de Oliveira Santos, AD; do Nascimento, MTL; Dos Santos, RF; Felix, LC; Hauser-Davis, RA; Neto, JAB; Sanson, AL | 1 |
| Adema, GJ; Ansems, M; Raaijmakers, TK; Scheffer, GJ; van den Bijgaart, RJE | 1 |
| Al-Mousa, AA; Alsalem, MI; Altarifi, AA; Neubert, JK; Nuseir, KQ; Qaoud, AK; Younis, BA | 1 |
| Ailijiang, N; Chang, J; He, C; Mamat, A; Pu, M; Wu, M; Zhang, Q | 1 |
| Benedek, T; Bornemann, TLV; Hussein, D; Kriszt, B; Maróti, G; Menashe, O; Pápai, M; Plewka, J; Probst, AJ; Táncsics, A | 1 |
| Aluigi, A; Casettari, L; Khorshid, S; Maurizii, G; Moroni, S; Tiboni, M | 1 |
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| Baghban, AA; Dianat, O; Etemadi, A; Naseri, M; Salem, S; Vatankhah, M; Zargar, N | 1 |
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| Akinsete, SJ; Egbeyemi, MM; Ewemoje, TA; Lateef, SA; Omobowale, MO | 1 |
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52 review(s) available for diclofenac and ibuprofen
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship | 2016 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Glucuronides as Potential Anionic Substrates of Human Cytochrome P450 2C8 (CYP2C8).
Topics: Anions; Binding Sites; Cytochrome P-450 CYP2C8; Drug Interactions; Glucuronides; Humans; Ligands | 2017 |
Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Molecular Structure | 2019 |
Contemporary advances of cyclic molecules proposed for inflammation.
Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Humans; Inflammation; Molecular Structure; Structure-Activity Relationship | 2021 |
[Drug therapy of ankylosing spondyloarthritis (Bechterew's disease)].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Apazone; Butadienes; Cyclophosphamide; Diclofenac; Drug Combinations; Drug Evaluation; Glycolates; Gold; Humans; Ibuprofen; Indomethacin; Ketoprofen; Levamisole; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates; Spondylitis, Ankylosing; Sulindac | 1978 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diclofenac; Drug Hypersensitivity; Gastrointestinal Diseases; Hematologic Diseases; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Diseases; Kinetics; Naproxen; Phenylbutazone; Piroxicam; Salicylates; Thiazines | 1986 |
Clinical pharmacology of pediatric antipyretic drugs.
Topics: Acetaminophen; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Choline; Diclofenac; Drug Combinations; Humans; Ibuprofen; Kinetics; Naproxen; Salicylates | 1985 |
Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Diclofenac; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Phenylbutyrates; Piroxicam; Propionates; Sulindac; Thiazines | 1982 |
Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin.
Topics: Adult; Animals; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Female; Gastric Mucosa; Gout; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Phenylacetates; Platelet Aggregation; Rheumatic Diseases; Spondylitis, Ankylosing; Ulcer | 1980 |
Central antinociceptive effects of non-steroidal anti-inflammatory drugs and paracetamol. Experimental studies in the rat.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Behavior, Animal; Brain; Chemoreceptor Cells; Diclofenac; Ibuprofen; Male; Mechanoreceptors; Naloxone; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Serotonin; Spinal Cord; Thermoreceptors | 1995 |
Peri-operative use of nonsteroidal anti-inflammatory drugs in children: analgesic efficacy and bleeding.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Diclofenac; Drug Administration Schedule; Humans; Ibuprofen; Infant; Ketorolac; Pain, Postoperative; Postoperative Hemorrhage; Randomized Controlled Trials as Topic; Tolmetin | 1997 |
Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Codeine; Dextropropoxyphene; Diclofenac; Humans; Ibuprofen; Morphine; Ondansetron; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic; Reproducibility of Results; Tramadol; Transcutaneous Electric Nerve Stimulation; Treatment Outcome | 1998 |
Adverse upper gastrointestinal effects of rofecoxib compared with NSAIDs.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Nabumetone; Osteoarthritis; Peptic Ulcer; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Randomized Controlled Trials as Topic; Sulfones | 1999 |
Single dose oral ibuprofen and diclofenac for postoperative pain.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Pain, Postoperative | 2000 |
Celecoxib clinical profile.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; In Vitro Techniques; Isoenzymes; Kidney Diseases; Membrane Proteins; Middle Aged; Naproxen; Osteoarthritis; Pain; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Treatment Outcome | 2000 |
COX-2 inhibitors. Are they nonsteroidal anti-inflammatory drugs with a better safety profile?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Forecasting; Humans; Ibuprofen; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2001 |
[Meta-analysis of the efficacy of adenosylmethionine and oxaceprol in the treatment of osteoarthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Confidence Intervals; Data Interpretation, Statistical; Diclofenac; Humans; Hydroxyproline; Ibuprofen; Osteoarthritis; Placebos; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Therapeutic Equivalency | 2002 |
Postoperative hemorrhage with nonsteroidal anti-inflammatory drug use after tonsillectomy: a meta-analysis.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Diclofenac; Humans; Ibuprofen; Middle Aged; Postoperative Hemorrhage; Risk Assessment; Tonsillectomy | 2003 |
[Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; China; Diclofenac; Humans; Ibuprofen; Meloxicam; Nabumetone; Naproxen; Osteoarthritis; Oxaprozin; Propionates; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiazoles | 2003 |
Migraine headache.
Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Diclofenac; Drug Therapy, Combination; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2003 |
Migraine headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Sumatriptan; Triazoles; Tryptamines | 2004 |
Ulcers, Helicobacter pylori infection, platelets and gastrointestinal complications of non-steroidal anti-inflammatory drugs: what are the connections?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclooxygenase Inhibitors; Diclofenac; Gastrointestinal Hemorrhage; Helicobacter Infections; Humans; Ibuprofen; Lactones; Naproxen; Peptic Ulcer; Risk Factors; Sulfones | 2002 |
Non-steroidal antiinflammatory drugs and the risk of acute myocardial infarction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cohort Studies; Diclofenac; Dose-Response Relationship, Drug; Humans; Ibuprofen; Lactones; Myocardial Infarction; Naproxen; Risk Factors; Sulfones | 2006 |
Is any one analgesic superior for episodic tension-type headache?
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Ibuprofen; Ketoprofen; Naproxen; Nonprescription Drugs; Secondary Prevention; Tension-Type Headache; Treatment Outcome | 2006 |
[Postoperative pain therapy in otolaryngological department].
Topics: Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Diclofenac; Humans; Ibuprofen; Morphine; Otorhinolaryngologic Surgical Procedures; Pain, Postoperative; Treatment Outcome | 2006 |
Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Diclofenac; Humans; Ibuprofen; Naproxen | 2011 |
Interventions for the management of temporomandibular joint osteoarthritis.
Topics: Anti-Inflammatory Agents; Betamethasone; Diclofenac; Glucosamine; Humans; Hyaluronic Acid; Ibuprofen; Occlusal Splints; Osteoarthritis; Randomized Controlled Trials as Topic; Temporomandibular Joint Disorders; Viscosupplements | 2012 |
Pharmacogenetics of nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Celecoxib; Cytochrome P-450 CYP2C9; Diclofenac; Humans; Ibuprofen; Indomethacin; Pharmacogenetics; Pyrazoles; Sulfonamides | 2012 |
Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Vessels; Coronary Disease; Cyclooxygenase 2 Inhibitors; Diclofenac; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Ibuprofen; Myocardial Infarction; Naproxen; Stroke; Vascular Diseases | 2013 |
Cardiovascular risks associated with low-dose ibuprofen and diclofenac as used OTC.
Topics: Cardiovascular Diseases; Diclofenac; Humans; Ibuprofen; Nonprescription Drugs; Risk Factors | 2014 |
Topical therapies in the management of chronic pain.
Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chronic Pain; Diclofenac; Humans; Ibuprofen; Irritants; Ketoprofen; Lidocaine; Musculoskeletal Pain; Neoplasms; Neuralgia; Neuralgia, Postherpetic; Osteoarthritis, Knee; Palliative Care | 2013 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Aged; Analgesics; Caffeine; Chemotherapy, Adjuvant; Diclofenac; Drug Synergism; Dysmenorrhea; Female; Headache; Humans; Ibuprofen; Male; Middle Aged; ortho-Aminobenzoates; Pain, Postoperative; Postpartum Period; Pregnancy; Randomized Controlled Trials as Topic | 2014 |
Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: a systematic review and network meta-analysis.
Topics: Acetaminophen; Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Hyaluronic Acid; Ibuprofen; Injections, Intra-Articular; Naproxen; Osteoarthritis, Knee; Pain; Pyrazoles; Sulfonamides; Treatment Outcome; Viscosupplements | 2015 |
[Cardiovascular side effects of non-steroidal anti-inflammatory drugs in the light of recent recommendations. Diclofenac is not more dangerous].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cardiovascular System; Diclofenac; Drug Interactions; Humans; Ibuprofen; Naproxen | 2015 |
Ibuprofen for acute treatment of episodic tension-type headache in adults.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Ketoprofen; Naproxen; Numbers Needed To Treat; Pain Measurement; Piroxicam; Randomized Controlled Trials as Topic; Tension-Type Headache; Time Factors | 2015 |
Treatment for superficial infusion thrombophlebitis of the upper extremity.
Topics: Anti-Inflammatory Agents; Anticoagulants; Catheterization, Peripheral; Dalteparin; Diclofenac; Drug Combinations; Drugs, Chinese Herbal; Escin; Gels; Heparin; Heparinoids; Humans; Ibuprofen; Nitroglycerin; Pentosan Sulfuric Polyester; Phospholipids; Polydeoxyribonucleotides; Randomized Controlled Trials as Topic; Thrombophlebitis; Upper Extremity | 2015 |
Nonaspirin Nonsteroidal Anti-Inflammatory Drugs and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Observational Studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cerebral Hemorrhage; Diclofenac; Humans; Ibuprofen; Incidence; Indomethacin; Lactones; Meloxicam; Naproxen; Observational Studies as Topic; Odds Ratio; Piroxicam; Proportional Hazards Models; Stroke; Sulfones; Thiazines; Thiazoles | 2016 |
Non-steroidal anti-inflammatory drugs for chronic low back pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Diclofenac; Disability Evaluation; Humans; Ibuprofen; Indomethacin; Low Back Pain; Pain Measurement; Piroxicam; Randomized Controlled Trials as Topic | 2016 |
How polymorphisms of the cytochrome P450 genes affect ibuprofen and diclofenac metabolism and toxicity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytochrome P-450 CYP2C8; Cytochrome P-450 Enzyme System; Diclofenac; Genetic Predisposition to Disease; Humans; Ibuprofen; Peptic Ulcer; Polymorphism, Genetic | 2016 |
Topical NSAIDs for Acute Musculoskeletal Pain in Adults.
Topics: Acute Pain; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Ketoprofen; Musculoskeletal Pain; Treatment Outcome | 2016 |
Topics: Analgesics; Aspirin; Diclofenac; Humans; Ibuprofen; Migraine Disorders; Pyrrolidines; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Tryptamines | 2017 |
A systematic review and meta-analysis of oxaceprol in the management of osteoarthritis: An evidence from randomized parallel-group controlled trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Diclofenac; Humans; Hydroxyproline; Ibuprofen; Osteoarthritis; Randomized Controlled Trials as Topic; Sample Size | 2019 |
Efficacy and safety of over-the-counter analgesics for primary dysmenorrhea: A network meta-analysis.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Dysmenorrhea; Female; Humans; Ibuprofen; Ketoprofen; Middle Aged; Naproxen; Network Meta-Analysis; Nonprescription Drugs; Treatment Outcome; Young Adult | 2020 |
Toxicity of the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) acetylsalicylic acid, paracetamol, diclofenac, ibuprofen and naproxen towards freshwater invertebrates: A review.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ecosystem; Fresh Water; Humans; Ibuprofen; Invertebrates; Naproxen | 2020 |
Systematic Review and Meta-Analysis of the Association Between Non-Steroidal Anti-Inflammatory Drugs and Operative Bleeding in the Perioperative Period.
Topics: Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Blood Transfusion; Diclofenac; Humans; Ibuprofen; Ketorolac; Pain, Postoperative; Pain, Procedural; Perioperative Period; Postoperative Hemorrhage; Surgical Procedures, Operative; Treatment Outcome | 2021 |
Metabolism of non-steroidal anti-inflammatory drugs by non-target wild-living organisms.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Naproxen; Pharmaceutical Preparations | 2021 |
Pharmaceuticals as emerging pollutants: Case naproxen an overview.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Environmental Pollutants; Ibuprofen; Naproxen; Pharmaceutical Preparations; Water Pollutants, Chemical | 2022 |
Lessons from 20 years with COX-2 inhibitors: Importance of dose-response considerations and fair play in comparative trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Fibrinolytic Agents; Humans; Ibuprofen; Lactones; Naproxen; Prostaglandins; Prostaglandins I; Sulfones; Thromboxanes | 2022 |
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Child; Chronic Disease; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Infant; Ketoprofen; Ketorolac; Meloxicam; Naproxen; Niflumic Acid; Pain | 2022 |
Occurrence, toxicity, impact and removal of selected non-steroidal anti-inflammatory drugs (NSAIDs): A review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Naproxen; Wastewater; Water; Water Pollutants, Chemical | 2023 |
81 trial(s) available for diclofenac and ibuprofen
| Article | Year |
|---|---|
A comparison of the short-term effects of ibuprofen and diclofenac in spondylosis.
Topics: Adult; Aged; Diclofenac; Female; Humans; Ibuprofen; Lumbar Vertebrae; Male; Middle Aged; Palliative Care; Phenylacetates; Physical Therapy Modalities; Spinal Osteophytosis | 1978 |
[Clinical testing of diclofenac sodium in degenerative extra-articular rheumatic diseases].
Topics: Adult; Clinical Trials as Topic; Diclofenac; Drug Evaluation; Humans; Ibuprofen; Middle Aged; Periarthritis; Phenylacetates; Rheumatic Diseases | 1977 |
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin | 1979 |
Tolfenamic acid in the treatment of rheumatoid arthritis.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Drug Evaluation; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; ortho-Aminobenzoates; Phenylbutazone; Prednisone; Time Factors | 1979 |
[Comparative study of the therapeutic efficacy and tolerance of lysine p-isobutylphenylpropionate and diclofenac in variously located forms of arthrosis].
Topics: Adult; Aged; Clinical Trials as Topic; Diclofenac; Drug Tolerance; Female; Humans; Ibuprofen; Joint Diseases; Male; Middle Aged; Phenylacetates | 1978 |
Analysis of the Brazilian literature on diclofenac sodium (Voltarol).
Topics: Arthritis, Rheumatoid; Brazil; Clinical Trials as Topic; Diclofenac; Drug Tolerance; Female; Humans; Ibuprofen; Indomethacin; Male; Osteoarthritis; Time Factors | 1979 |
Diclofenac sodium (Voltarol): a double-blind comparative study with ibuprofen in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Female; Hemoglobins; Humans; Ibuprofen; Male; Middle Aged; Phenylacetates; Sex Factors | 1979 |
On the medicinal efficacy of dietetic therapy in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Combined Modality Therapy; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Prednisolone | 1992 |
Anti-inflammatory and combined anti-inflammatory/analgesic medication in the early management of iliotibial band friction syndrome. A clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Athletic Injuries; Codeine; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Humans; Ibuprofen; Ilium; Knee Injuries; Ligaments, Articular; Pain Measurement; Tibia | 1991 |
The effect of magnesium hydroxide on the oral absorption of ibuprofen, ketoprofen and diclofenac.
Topics: Adult; Biological Availability; Diclofenac; Female; Humans; Ibuprofen; Intestinal Absorption; Ketoprofen; Magnesium Hydroxide | 1991 |
[The dynamics of the analgesic effect of non-steroidal antirheumatic drugs. Ibuprofenlysinate versus diclofenac].
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Lysine; Pain Measurement; Random Allocation | 1989 |
International experience with diclofenac in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone | 1986 |
Efficacy and safety of diclofenac sodium in rheumatoid arthritis. Experience in the United States.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Peptic Ulcer; United States | 1986 |
International experiences with diclofenac in osteoarthritis.
Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Naproxen; Osteoarthritis; Random Allocation; Sulindac | 1986 |
Worldwide safety experience with diclofenac.
Topics: Adult; Aged; Aspirin; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Gastrointestinal Diseases; Gastroscopy; Humans; Ibuprofen; Kidney Diseases; Middle Aged; Naproxen; Occult Blood; Piroxicam; Thiazines | 1986 |
The influence of ibuprofen, diclofenac and sulindac on the blood pressure lowering effect of hydrochlorothiazide.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Creatinine; Diclofenac; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Indenes; Male; Middle Aged; Potassium; Renin; Sulindac | 1987 |
Worldwide clinical safety experience with diclofenac.
Topics: Aspirin; Clinical Trials as Topic; Diclofenac; France; Humans; Ibuprofen; Japan; Osteoarthritis; Rheumatic Diseases; United Kingdom; United States | 1985 |
Diclofenac sodium in the treatment of painful stiff shoulder.
Topics: Clinical Trials as Topic; Diclofenac; Humans; Ibuprofen; Middle Aged; Periarthritis; Phenylacetates; Shoulder Joint | 1983 |
Treatment of periarthritis of the shoulder: a comparison of ibuprofen and diclofenac.
Topics: Adult; Aged; Clinical Trials as Topic; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Periarthritis; Phenylacetates; Shoulder Joint | 1984 |
Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm.
Topics: Adolescent; Adult; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Female; Forearm; Humans; Hyperemia; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Regional Blood Flow; Thiazines | 1983 |
Comparison of the analgesic effect of ten nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Ketoprofen; Male; Middle Aged; Naproxen; ortho-Aminobenzoates; Quinazolines | 1984 |
Diclofenac and ibuprofen in rheumatoid arthritis and osteoarthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Osteoarthritis; Phenylacetates | 1980 |
Diclofenac sodium (Voltaren) and ibuprofen in rheumatoid arthritis. A randomized double-blind study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Phenylacetates; Random Allocation | 1980 |
A study of the efficacy and tolerability of diclofenac and ibuprofen in osteoarthritis of the hip.
Topics: Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Hip Joint; Humans; Ibuprofen; Male; Middle Aged; Osteoarthritis; Phenylacetates; Random Allocation | 1981 |
Arthrotec, diclofenac and ibuprofen in general practice.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Drug Combinations; Female; Humans; Ibuprofen; Male; Middle Aged; Misoprostol | 1994 |
A placebo-controlled comparative evaluation of diclofenac dispersible versus ibuprofen in postoperative pain after third molar surgery.
Topics: Administration, Oral; Adult; Aged; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Molar, Third; Pain Measurement; Pain, Postoperative; Tooth Extraction; Tooth, Impacted | 1994 |
Safety experience with nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Efficacy and safety of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in the elderly.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Male; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Efficacy of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Life Style; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
The analgesic efficacy of diclofenac dispersible and ibuprofen in postoperative pain after dental extraction.
Topics: Administration, Oral; Adolescent; Adult; Analgesia; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; Molar, Third; Pain, Postoperative; Tooth Extraction; Tooth, Impacted | 1993 |
Nonsteroidal anti-inflammatory drug use in relation to major upper gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Diclofenac; Female; Gastrointestinal Hemorrhage; Humans; Hungary; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Risk Factors; Sweden; United States | 1993 |
Comparative efficacy of diclofenac dispersible 50 mg and ibuprofen 400 mg in patients with primary dysmenorrhea. A randomized, double-blind, within-patient, placebo-controlled study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diclofenac; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Pain; Pain Measurement; Patient Compliance | 1995 |
Ibuprofen and diclofenac sodium in the treatment of osteoarthritis: a comparative trial of two once-daily sustained-release NSAID formulations.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Osteoarthritis; Pain; Single-Blind Method; Treatment Outcome | 1996 |
[Double-blind comparative study of the effectiveness and tolerance of 900 mg dexibuprofen and 150 mg diclofenac sodium in patients with painful gonarthrosis].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Ibuprofen; Knee Joint; Male; Middle Aged; Osteoarthritis; Pain Measurement; Stereoisomerism; Treatment Outcome | 1997 |
The comparative efficacy of aceclofenac and ibuprofen in postoperative pain after third molar surgery.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chi-Square Distribution; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Linear Models; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Tooth Extraction; Treatment Outcome | 1998 |
Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans.
Topics: Administration, Oral; Analysis of Variance; Animals; Body Temperature; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Administration Schedule; Fever; Ibuprofen; Isoenzymes; Lactones; Lipopolysaccharides; Prostaglandin-Endoperoxide Synthases; Saimiri; Sulfones; Treatment Outcome | 1999 |
Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study.
Topics: Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Isoenzymes; Male; Membrane Proteins; Middle Aged; Osteoarthritis; Peptic Ulcer; Proportional Hazards Models; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2000 |
Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers.
Topics: Adolescent; Adult; Bleeding Time; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Lipopolysaccharides; Meloxicam; Membrane Proteins; Middle Aged; Naproxen; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfones; Thiazines; Thiazoles; Thromboxane B2 | 2000 |
Endoscopic evaluation of the gastrotolerance of short-term antalgic treatment with low dose k-diclofenac: a comparison of ibuprofen and aspirin.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Duodenum; Endoscopy, Gastrointestinal; Female; Humans; Ibuprofen; Male; Pain; Single-Blind Method; Stomach | 2001 |
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Drug Interactions; Drug Therapy, Combination; Humans; Ibuprofen; Isoenzymes; Lactones; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Sulfones; Thromboxane B2 | 2001 |
Comparison of thromboembolic events in patients treated with celecoxib, a cyclooxygenase-2 specific inhibitor, versus ibuprofen or diclofenac.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular System; Celecoxib; Coronary Thrombosis; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; Pyrazoles; Sulfonamides | 2002 |
Limitation of the in vitro whole blood assay for predicting the COX selectivity of NSAIDs in clinical use.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Diclofenac; Humans; Ibuprofen; Isoenzymes; Male; Meloxicam; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; Stereoisomerism; Thiazines; Thiazoles | 2002 |
Effects of non-steroidal anti-inflammatory drugs on hypertension control using angiotensin converting enzyme inhibitors and thiazide diuretics.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Diclofenac; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Lisinopril; Middle Aged; Osteoarthritis; Sulindac; Treatment Outcome | 2001 |
Incidence of gastroduodenal ulcers associated with valdecoxib compared with that of ibuprofen and diclofenac in patients with osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Diclofenac; Double-Blind Method; Duodenal Ulcer; Female; Helicobacter Infections; Helicobacter pylori; Humans; Ibuprofen; Isoenzymes; Isoxazoles; Male; Membrane Proteins; Middle Aged; Osteoarthritis; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases; Stomach Ulcer; Sulfonamides; Treatment Outcome | 2002 |
Low-dose diclofenac potassium in the treatment of episodic tension-type headache.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Palliative Care; Salvage Therapy; Tension-Type Headache; Time Factors; Treatment Outcome | 2003 |
A multicenter, randomized, double-blind, double-dummy, placebo- and active-controlled, parallel-group comparison of diclofenac-K and ibuprofen for the treatment of adults with influenza-like symptoms.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Administration Schedule; Female; Fever; Headache; Humans; Ibuprofen; Influenza, Human; Male; Pain; Syndrome; Treatment Outcome | 2003 |
Relief of acute low back pain with diclofenac-K 12.5 mg tablets: a flexible dose, ibuprofen 200 mg and placebo-controlled clinical trial.
Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Administration Schedule; Female; Humans; Ibuprofen; Low Back Pain; Male; Middle Aged | 2003 |
Analgesic efficacy of single oral doses of lumiracoxib and ibuprofen in patients with postoperative dental pain.
Topics: Adolescent; Adult; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; Molar, Third; Organic Chemicals; Pain, Postoperative; Pilot Projects; Tooth Extraction; Treatment Outcome | 2004 |
Reduced incidence of gastroduodenal ulcers associated with lumiracoxib compared with ibuprofen in patients with rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Middle Aged; Organic Chemicals; Peptic Ulcer; Treatment Outcome | 2004 |
An evaluation of the in vitro metabolism data for predicting the clearance and drug-drug interaction potential of CYP2C9 substrates.
Topics: Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cross-Over Studies; Cytochrome P-450 CYP2C9; Diclofenac; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Ibuprofen; In Vitro Techniques; Indoles; Male; Mass Spectrometry; Microsomes, Liver; Middle Aged; Tolbutamide | 2004 |
Therapeutic arthritis research and gastrointestinal event trial of lumiracoxib - study design and patient demographics.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Health Status; Humans; Ibuprofen; Isoenzymes; Membrane Proteins; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Peptic Ulcer; Prognosis; Prostaglandin-Endoperoxide Synthases; Risk Factors | 2004 |
A double-blind randomised controlled clinical trial of the effect of preoperative ibuprofen, diclofenac, paracetamol with codeine and placebo tablets for relief of postoperative pain after removal of impacted third molars.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Ascorbic Acid; Codeine; Diclofenac; Double-Blind Method; Epidemiologic Methods; Female; Humans; Ibuprofen; Male; Middle Aged; Molar, Third; Pain Measurement; Pain, Postoperative; Premedication; Tooth Extraction; Tooth, Impacted; Treatment Outcome | 2004 |
Gastroduodenal safety and tolerability of lumiracoxib compared with Ibuprofen and celecoxib in patients with osteoarthritis.
Topics: Aged; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Organic Chemicals; Osteoarthritis; Peptic Ulcer; Pyrazoles; Risk Factors; Sulfonamides | 2004 |
Relationships between the concentrations of prostaglandins and the nonsteroidal antiinflammatory drugs indomethacin, diclofenac, and ibuprofen.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Cross-Over Studies; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Ibuprofen; Indomethacin; Male; Tablets; Time Factors | 2005 |
Valdecoxib is associated with improved dyspepsia-related health compared with nonspecific NSAIDs in patients with osteoarthritis or rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Dyspepsia; Female; Humans; Ibuprofen; Isoxazoles; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Patient Satisfaction; Placebos; Quality of Life; Sulfonamides; Treatment Outcome; Upper Gastrointestinal Tract | 2005 |
COX-2 inhibitors and pain after oral surgery - pertinent papers 2002-2003.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Ibuprofen; Injections, Intravenous; Isoxazoles; Lactones; Pain, Postoperative; Preanesthetic Medication; Prodrugs; Pyrazoles; Sulfonamides; Sulfones; Tooth Extraction | 2006 |
Modification of pepsinogen I levels and their correlation with gastrointestinal injury after administration of dexibuprofen, ibuprofen or diclofenac: a randomized, open-label, controlled clinical trial.
Topics: Administration, Oral; Adult; Cyclooxygenase Inhibitors; Diclofenac; Endoscopy, Gastrointestinal; Female; Humans; Ibuprofen; Indoprofen; Intestinal Mucosa; Male; Middle Aged; Pepsinogen A; Rheumatic Diseases | 2006 |
Cardiorenal effects of celecoxib as compared with the nonsteroidal anti-inflammatory drugs diclofenac and ibuprofen.
Topics: Acid-Base Equilibrium; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Pressure; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Edema; Female; Glomerular Filtration Rate; Heart; Humans; Hyponatremia; Ibuprofen; Kidney; Male; Middle Aged; Osteoarthritis; Pyrazoles; Sulfonamides | 2006 |
Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Heart Defects, Congenital; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis | 2007 |
Effect of risk factors on complicated and uncomplicated ulcers in the TARGET lumiracoxib outcomes study.
Topics: Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Diclofenac; Duodenal Ulcer; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Risk Factors; Risk Reduction Behavior; Stomach Ulcer | 2007 |
Clinical trial: comparison of the gastrointestinal safety of lumiracoxib with traditional nonselective nonsteroidal anti-inflammatory drugs early after the initiation of treatment--findings from the Therapeutic Arthritis Research and Gastrointestinal Even
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Statistics as Topic | 2008 |
Effect on blood pressure of lumiracoxib versus ibuprofen in patients with osteoarthritis and controlled hypertension: a randomized trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Hypertension; Ibuprofen; Middle Aged; Osteoarthritis; Treatment Outcome | 2008 |
A comparison of the blood pressure changes of lumiracoxib with those of ibuprofen and naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Creatinine; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Pain Measurement | 2008 |
Multiple electrode aggregometry for ex-vivo detection of the anti-platelet effect of non-opioid analgesic drugs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Diclofenac; Electrodes; Equipment Design; Humans; Ibuprofen; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reproducibility of Results; Time Factors | 2009 |
The interaction of ibuprofen and diclofenac with aspirin in healthy volunteers.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Delayed-Action Preparations; Diclofenac; Drug Interactions; Female; Humans; Ibuprofen; Male; Middle Aged; Platelet Aggregation; Risk Factors; Thromboxane B2 | 2009 |
Preparation and characterization of PEG-modified polyurethane pressure-sensitive adhesives for transdermal drug delivery.
Topics: Adhesives; Administration, Cutaneous; Caproates; Cyanates; Diclofenac; Drug Delivery Systems; Female; Humans; Ibuprofen; Isocyanates; Male; Methimazole; Polyethylene Glycols; Polymers; Polyurethanes; Skin Irritancy Tests; Solubility; Temperature; Tin | 2009 |
Antipyretic agents for preventing recurrences of febrile seizures: randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Child, Preschool; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Infant; Male; Placebos; Secondary Prevention; Seizures, Febrile; Suppositories; Time Factors; Treatment Outcome | 2009 |
The effects of lumiracoxib 100 mg once daily vs. ibuprofen 600 mg three times daily on the blood pressure profiles of hypertensive osteoarthritis patients taking different classes of antihypertensive agents.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Ibuprofen; Male; Middle Aged; Osteoarthritis; Treatment Outcome | 2010 |
[Application of a seven-day buprenorphine transdermal patch in multimorbid patients on long-term ibuprofen or diclofenac].
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Buprenorphine; Chronic Disease; Diclofenac; Drug Administration Schedule; Drug Substitution; Female; Humans; Ibuprofen; Long-Term Care; Male; Middle Aged; Pain; Pain Measurement; Prospective Studies | 2011 |
Randomized, open-label, 5-way crossover study to evaluate the pharmacokinetic/pharmacodynamic interaction between furosemide and the non-steroidal anti-inflammatory drugs diclofenac and ibuprofen in healthy volunteers.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Cross-Over Studies; Diclofenac; Diuretics; Drug Interactions; Female; Furosemide; Humans; Ibuprofen; Male; Middle Aged; Transdermal Patch; Young Adult | 2011 |
Endoscopic evaluation of the gastro-duodenal tolerance of short-term analgesic treatment with 25 mg diclofenac-K liquid capsules.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capsules; Diclofenac; Drug Tolerance; Duodenum; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Humans; Ibuprofen; Male; Pain Measurement; Tablets; Time Factors; Young Adult | 2012 |
Efficacy of extended-release oral diclofenac in postoperative pain management after photorefractive keratectomy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism; Case-Control Studies; Diclofenac; Female; Humans; Ibuprofen; Male; Myopia; Pain Management; Pain, Postoperative; Photorefractive Keratectomy; Postoperative Complications; Prospective Studies; Young Adult | 2013 |
The effects of nonsteroidal anti-inflammatory drugs on clinical outcomes, synovial fluid cytokine concentration and signal transduction pathways in knee osteoarthritis. A randomized open label trial.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Cytokines; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Osteoarthritis, Knee; Pyrazoles; Quality of Life; Signal Transduction; Sulfonamides; Synovial Fluid; Treatment Outcome | 2013 |
Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac.
Topics: Administration, Ophthalmic; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Binding Sites; Cataract; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Serum Albumin | 2014 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Lidocaine; Male; Mefenamic Acid; Pain; Pain Measurement; Pain, Postoperative; Placebos; Pulpitis; Root Canal Preparation; Root Canal Therapy | 2016 |
Comparison of paracetamol, ibuprofen, and diclofenac potassium for pain relief following dental extractions and deep cavity preparations.
Topics: Acetaminophen; Adult; Anesthesia, Local; Anti-Inflammatory Agents, Non-Steroidal; Dental Cavity Preparation; Diclofenac; Female; Humans; Ibuprofen; Male; Pain Measurement; Pain, Postoperative; Tooth Extraction | 2017 |
Efficacy and safety of adalimumab by intra-articular injection for moderate to severe knee osteoarthritis: An open-label randomized controlled trial.
Topics: Adalimumab; Aged; Antirheumatic Agents; Celecoxib; Diclofenac; Female; Humans; Hyaluronic Acid; Ibuprofen; Injections, Intra-Articular; Male; Meloxicam; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Patient Safety; Pilot Projects; Severity of Illness Index; Thiazines; Thiazoles; Treatment Outcome | 2018 |
Comparison of diclofenac gel, ibuprofen gel, and ibuprofen gel with levomenthol for the topical treatment of pain associated with musculoskeletal injuries.
Topics: Administration, Topical; Adolescent; Adult; Aged; Diclofenac; Female; Gels; Humans; Ibuprofen; Male; Menthol; Middle Aged; Musculoskeletal System; Pain; Survival Analysis; Young Adult | 2019 |
A randomized controlled trial of ibuprofen versus ketorolac versus diclofenac for acute, nonradicular low back pain.
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Ketorolac; Low Back Pain | 2021 |
Intravenous ibuprofen versus diclofenac plus orphenadrine in orthognathic surgery: a prospective, randomized, double-blind, controlled clinical study.
Topics: Acetaminophen; Adolescent; Adult; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Middle Aged; Orphenadrine; Orthognathic Surgery; Pain, Postoperative; Pirinitramide; Prospective Studies; Young Adult | 2022 |
Analgesic Efficacy of Ibuprofen and Diclofenac Potassium on Postoperative Endodontic Pain in Maxillary and Mandibular First Molars with Irreversible Pulpitis: A Randomised Controlled Trial.
Topics: Analgesics; Diclofenac; Humans; Ibuprofen; Molar; Pain, Postoperative; Prospective Studies; Pulpitis | 2023 |
458 other study(ies) available for diclofenac and ibuprofen
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Nonsteroidal antiinflammatory agents. 14. Synthesis and pharmacological profile of 6-chloro-5-(cyclopentylmethyl)indan-1-carboxylic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Edema; Indans; Indenes; Male; Rats; Rats, Inbred Strains | 1984 |
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis | 1999 |
Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.
Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; Cloning, Molecular; Dehydroepiandrosterone Sulfate; Estrone; Humans; Kidney; Kinetics; Membrane Proteins; Molecular Sequence Data; Ochratoxins; Oocytes; Placenta; RNA, Messenger; Sequence Alignment; Sulfates; Xenopus | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis | 2001 |
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors | 2003 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship | 2004 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism | 2005 |
The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclooxygenase Inhibitors; Disease Models, Animal; Flurbiprofen; Mice; Peptide Fragments | 2006 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor.
Topics: Albumins; Anti-Bacterial Agents; Binding Sites; Calorimetry; Fluorescence; Humans; ortho-Aminobenzoates; Protein Binding | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
NSAIDs revisited: putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARgamma).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalytic Domain; Computational Biology; Drug Design; Ligands; Models, Molecular; PPAR gamma; Protein Conformation; Software | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Regioselective reaction: synthesis and pharmacological study of Mannich bases containing ibuprofen moiety.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspergillus; Edema; Escherichia coli; Ibuprofen; Inflammation; Mannich Bases; Mice; Pain; Rats; Rats, Wistar; Schiff Bases; Staphylococcus aureus; Triazoles | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver.
Topics: Animals; Cells, Cultured; Child, Preschool; Chimera; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drugs, Investigational; Female; Half-Life; Hepatocytes; Humans; Immunomagnetic Separation; Liver; Male; Metabolic Clearance Rate; Mice; Mice, SCID; Recombinant Proteins; Species Specificity; Urokinase-Type Plasminogen Activator | 2012 |
Binding of ibuprofen, ketorolac, and diclofenac to COX-1 and COX-2 studied by saturation transfer difference NMR.
Topics: Animals; Binding, Competitive; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Female; Ibuprofen; Ketorolac; Magnetic Resonance Spectroscopy; Male; Sheep | 2011 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Bone-targeting glycol and NSAIDS ester prodrugs of rhein: synthesis, hydroxyapatite affinity, stability, anti-inflammatory, ulcerogenicity index and pharmacokinetics studies.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Chemistry Techniques, Synthetic; Drug Stability; Durapatite; Esters; Female; Glycols; Male; Mice; Prodrugs; Rats; Ulcer | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles | 2013 |
A facile synthesis, anti-inflammatory and analgesic activity of isoxazolyl-2,3-dihydrospiro[benzo[f]isoindole-1,3'-indoline]-2',4,9-triones.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dose-Response Relationship, Drug; Edema; Female; Isoindoles; Isoxazoles; Male; Molecular Conformation; Rats; Rats, Wistar | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein.
Topics: Fatty Acid-Binding Proteins; Fluorescent Dyes; Humans; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spectrometry, Fluorescence | 2014 |
Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors.
Topics: | 2014 |
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid | 2015 |
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hyperlipidemias; Hypolipidemic Agents; Morpholines; Rats; Triglycerides | 2016 |
1-Aryl-1H- and 2-aryl-2H-1,2,3-triazole derivatives blockade P2X7 receptor in vitro and inflammatory response in vivo.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Inflammation; Lipopolysaccharides; Mice; Molecular Structure; Pleurisy; Receptors, Purinergic P2X7; Structure-Activity Relationship; Triazoles | 2017 |
Design of balanced COX inhibitors based on anti-inflammatory and/or COX-2 inhibitory ascidian metabolites.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Mice; Models, Molecular; Molecular Structure; RAW 264.7 Cells; Sheep; Structure-Activity Relationship; Urochordata | 2019 |
Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbonic Anhydrase Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Drug Development; Humans; Male; Molecular Dynamics Simulation; Pain; Rats; Rats, Sprague-Dawley | 2020 |
The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Crystallography, X-Ray; Drug Design; Folic Acid; Folic Acid Antagonists; Humans; Models, Molecular; Tetrahydrofolate Dehydrogenase | 2020 |
Effects of some anti-rheumatic agents on copper-catalyzed thermal aggregation of gamma globulin.
Topics: Anti-Inflammatory Agents; Aspirin; Copper; Dexamethasone; Diclofenac; Flufenamic Acid; gamma-Globulins; Gold Sodium Thiomalate; Hot Temperature; Humans; Ibuprofen; Indans; Indomethacin; Penicillamine; Phenylbutazone; Prednisolone | 1979 |
Comparisons of tolerability findings in international clinical trials.
Topics: Arthritis, Rheumatoid; Aspirin; Cardiovascular System; Clinical Trials as Topic; Diclofenac; Drug Tolerance; Follow-Up Studies; Gastrointestinal Diseases; Hematologic Tests; Humans; Ibuprofen; Indomethacin; International Cooperation; Naproxen; Phenylacetates; Time Factors | 1979 |
[Irritative activity of a new anti-inflammatory agent 4-(p-chorophenyl)-2-phenyl-5-thiazoleacetic acid (CH-800) on the gastrointestinal tract in rats (author's transl)].
Topics: Acetates; Administration, Oral; Animals; Anti-Inflammatory Agents; Aspirin; Diclofenac; Digestive System; Ibuprofen; Indomethacin; Irritants; Male; Phenylbutazone; Rats; Stomach Ulcer; Thiazoles | 1979 |
Duodenal mucosal damage associated with chronic use of anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents; Aspirin; Diclofenac; Duodenal Ulcer; Endoscopy; Female; Fiber Optic Technology; Gastritis; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Male; Middle Aged | 1977 |
High-performance liquid chromatographic determination of naproxen, ibuprofen and diclofenac in plasma and synovial fluid in man.
Topics: Chromatography, High Pressure Liquid; Diclofenac; Humans; Ibuprofen; Naproxen; Reproducibility of Results; Spectrophotometry, Ultraviolet; Synovial Fluid | 1992 |
Effect of sulindac on prostaglandin synthesis in human and in cultured rat renal and vascular smooth muscle cells.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Animals; Arachidonic Acids; Cells, Cultured; Creatinine; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Kidney; Kidney Glomerulus; Male; Middle Aged; Muscle, Smooth, Vascular; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulindac | 1992 |
Suspected central nervous system toxicity from inadvertent nonsteroidal antiinflammatory drug overdose.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System Diseases; Diclofenac; Drug Overdose; Female; Humans; Ibuprofen; Indomethacin; Middle Aged; Poisoning | 1991 |
[Inhibition of thrombocyte function by non-steroidal anti-rheumatic agents: a comparative study between diclofenac, acemetacin, mefenamic acid and ibuprofen].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Indomethacin; Malondialdehyde; Mefenamic Acid; Platelet Aggregation; Thromboxanes | 1991 |
A prospective nationwide cross-sectional study of NSAID usage in 1331 patients with ankylosing spondylitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cross-Sectional Studies; Diclofenac; Female; Gold; Humans; Ibuprofen; Male; Methotrexate; Middle Aged; Naproxen; Penicillamine; Piroxicam; Prednisolone; Prospective Studies; Spondylitis, Ankylosing; Sulfasalazine; United Kingdom | 1990 |
Anti-inflammatory efficacy and gastrointestinal irritancy: comparative 1 month repeat oral dose studies in the rat with nabumetone, ibuprofen and diclofenac.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Butanones; Carrageenan; Diclofenac; Edema; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Ibuprofen; Male; Nabumetone; Rats; Rats, Inbred Strains | 1991 |
The effects of ibuprofen and diclofenac on the chemotaxis and adenosine triphosphate level of polymorphonuclear cells in vitro.
Topics: Adenosine Triphosphate; Cell Survival; Cells, Cultured; Chemotaxis, Leukocyte; Diclofenac; Humans; Ibuprofen; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Trypan Blue | 1990 |
Acquired Brown's syndrome in systemic lupus erythematosus: another ocular manifestation.
Topics: Adult; Diclofenac; Diplopia; Fever; Humans; Hydroxychloroquine; Ibuprofen; Lupus Erythematosus, Systemic; Male; Oculomotor Muscles; Pain; Tenosynovitis | 1990 |
Biliary elimination of non-steroidal anti-inflammatory drugs in patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Bile; Cholestasis; Common Bile Duct Diseases; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged | 1990 |
Central effect of the non-steroid anti-inflammatory agents, indomethacin, ibuprofen, and diclofenac, determined in C fibre-evoked activity in single neurones of the rat thalamus.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Diclofenac; Dose-Response Relationship, Drug; Female; Ibuprofen; Indomethacin; Male; Nerve Fibers; Neurons; Rats; Rats, Inbred Strains; Thalamus | 1990 |
Objective assessment of topical corticosteroids and non-steroidal anti-inflammatory drugs in methyl-nicotinate-induced skin inflammation.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Bufexamac; Clobetasol; Dermatitis, Contact; Diclofenac; Humans; Hydrocortisone; Ibuprofen; Indomethacin; Male; Nicotinic Acids; Niflumic Acid; Phenylbutazone; Regional Blood Flow; Skin | 1990 |
[Systemic application of antipyretic, non-opioid analgesics (1)].
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dipyrone; Humans; Ibuprofen | 1990 |
[Systemic application of antipyretic non-opioid analgesics (2)].
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Dipyrone; Humans; Ibuprofen | 1990 |
Sensitivity to insect stings in patients taking anti-inflammatory drugs.
Topics: Aged; Anaphylaxis; Bees; Diclofenac; Female; Humans; Hymenoptera; Ibuprofen; Insect Bites and Stings; Middle Aged; Wasps | 1986 |
Effect of diclofenac sodium on the arachidonic acid cascade.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Lipoxygenase Inhibitors; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Naproxen; Phospholipids; Piroxicam; Prostaglandins E; Rats; SRS-A; Thiazines; Triglycerides | 1986 |
The history of diclofenac.
Topics: Chemical Phenomena; Chemistry; Diclofenac; Humans; Hydrogen-Ion Concentration; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Naproxen; Phenylbutazone; Piroxicam; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Thiazines | 1986 |
Indomethacin and ibuprofen enhance anoxia-induced hyperemia in rat brain.
Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Diclofenac; Extracorporeal Circulation; Hyperemia; Hypoxia, Brain; Ibuprofen; Indomethacin; Male; Rats; Rats, Inbred Strains | 1986 |
[An ex-vivo technic for the pharmacologic evaluation of potential antiphlogistics by ex-vivo determination of the rate of malondialdehyde (MDA) formation using rat platelets].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Depression, Chemical; Diclofenac; Drug Evaluation, Preclinical; Ibuprofen; In Vitro Techniques; Kinetics; Malonates; Malondialdehyde; Rats | 1986 |
Effects of phenylbutazone and oxyphenbutazone on acidic drug detection in high performance thin layer chromatographic systems.
Topics: Animals; Chromatography, Thin Layer; Diclofenac; Female; Fenoprofen; Horses; Hydrogen-Ion Concentration; Ibuprofen; Oxyphenbutazone; Pharmaceutical Preparations; Phenylbutazone; Piroxicam; Sulindac | 1986 |
The history of diclofenac.
Topics: Diclofenac; History, 20th Century; Ibuprofen; Ketoprofen; Models, Molecular; Naproxen; Phenylbutazone; Piroxicam; Solubility; Structure-Activity Relationship; Thiazines | 1985 |
The effects of diclofenac sodium on arachidonic acid metabolism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Leukocytes; Lipoxygenase; Naproxen; Phospholipases A; Phospholipases A2; Phospholipids; Piroxicam; Prostaglandins E; SRS-A; Thiazines; Triglycerides | 1985 |
Effects of diclofenac sodium on arachidonic acid metabolism.
Topics: Arachidonic Acid; Arachidonic Acids; Diclofenac; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Monocytes; Naproxen; Neutrophils; Piroxicam; SRS-A; Thiazines | 1985 |
Effects of some anti-inflammatory drugs on 12 blood constituents: protocol for the study of in vivo effects of drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Chemical Analysis; Blood Urea Nitrogen; Cholesterol; Creatinine; Diclofenac; Humans; Ibuprofen; Indomethacin; Iron; Ketoprofen; Prospective Studies; Retrospective Studies; Serum Albumin; Time Factors; Triglycerides; Uric Acid | 1985 |
Determination of anti-inflammatory and antimitotic activities of non-steroid anti-inflammatory drugs ibuprofen, diclofenac sodium and fentiazac.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Capillary Permeability; Cell Division; Diclofenac; Female; Granuloma; Ibuprofen; Mitosis; Rats; Thiazoles; Time Factors | 1985 |
Diclofenac sodium in the treatment of rheumatoid arthritis and osteoarthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Pain | 1985 |
Diclofenac in the treatment of painful joints and traumatic tendinitis (including strains and sprains): a brief review.
Topics: Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Joint Diseases; Ketoprofen; Naproxen; Pain; Sprains and Strains; Tendinopathy | 1985 |
Effect on platelet aggregation of oral administration of 10 non-steroidal analgesics to humans.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Diclofenac; Diflunisal; Epinephrine; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Oxyphenbutazone; Piroxicam; Platelet Aggregation; Thiazines; Time Factors | 1984 |
Inhibition of prostaglandin E synthesis by steroidal and nonsteroidal antiinflammatory drugs in human synovial fibroblast cultures.
Topics: Anti-Inflammatory Agents; Cells, Cultured; Diclofenac; Fibroblasts; Humans; Hyaluronic Acid; Hydrocortisone; Ibuprofen; Indomethacin; Poly I-C; Prostaglandins E; Synovial Membrane | 1984 |
[Gold salts in the therapy of juvenile rheumatoid arthritis].
Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Diclofenac; Female; Gold; Humans; Ibuprofen; Male | 1983 |
Osteoarthritis and non-steroidal and anti-inflammatory drugs: a multi-centre comparative study.
Topics: Aged; Diclofenac; Female; Hip Joint; Humans; Ibuprofen; Indenes; Knee Joint; Male; Naproxen; Osteoarthritis; Sulindac | 1982 |
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Penicillamine; Phenylbutazone; Thrombocytopenia | 1980 |
Experimental murine schistosomiasis: reduced hepatic morbidity after pre- and/or post-infection treatment with ibuprofen or diclofenac sodium.
Topics: Animals; Cyclooxygenase Inhibitors; Diclofenac; Feces; gamma-Glutamyltransferase; Hydroxyproline; Ibuprofen; Liver; Liver Cirrhosis, Experimental; Male; Mice; Organ Size; Parasite Egg Count; Schistosomiasis mansoni; Schistosomicides; Time Factors | 1995 |
Effect of ibuprofen and diclofenac on the chemotaxis induced by substance P and transforming growth factor-beta on human monocytes and polymorphonuclear cells.
Topics: Arthritis; Chemotaxis; Diclofenac; Humans; Ibuprofen; In Vitro Techniques; Monocytes; Neutrophils; Substance P; Synovial Fluid; Transforming Growth Factor beta | 1993 |
Inhibitory effect of NSAIDs on the chemotaxis induced by substance P on human monocytes and polymorphonuclear cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Chemotaxis, Leukocyte; Diclofenac; Humans; Ibuprofen; Indomethacin; Leukocytes; Monocytes; Neutrophils; Piroxicam; Substance P | 1993 |
Concentration-response relationships for three nonsteroidal anti-inflammatory drugs in the rat intestine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane Permeability; Diclofenac; Dose-Response Relationship, Drug; Ibuprofen; Injections, Intravenous; Injections, Subcutaneous; Intestinal Mucosa; Intestines; Male; Piroxicam; Rats; Rats, Sprague-Dawley | 1995 |
[Interstitial nephritis caused by non-steroidal anti-inflammatory agents--report of 2 cases].
Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Female; Humans; Ibuprofen; Nephritis, Interstitial | 1995 |
Nonsteroidal antiinflammatory drugs: effects on normal and interleukin 1 treated human articular chondrocyte metabolism in vitro.
Topics: Cartilage, Articular; Cell Division; Cells, Cultured; Collagenases; Diclofenac; Dinoprostone; Extracellular Matrix; Humans; Ibuprofen; Interleukin-1; Interleukin-6; Naproxen; Reference Values; Salicylates | 1995 |
Alterations in the electroretinogram of newborn piglets by propionic acid-derivative nonsteroidal antiinflammatory drugs but not by indomethacin and diclofenac.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electroretinography; Flurbiprofen; Ibuprofen; Indomethacin; Naproxen; Photoreceptor Cells; Propionates; Prostaglandins; Retina; Swine | 1995 |
Induction of transcription factors in human T lymphocytes by aspirin-like drugs.
Topics: Adult; Base Sequence; Benzoquinones; Calcium; Cell Nucleus; Diclofenac; DNA-Binding Proteins; Female; Flurbiprofen; Gene Expression Regulation; Humans; Ibuprofen; Interleukin-2; Isoenzymes; Lactams, Macrocyclic; Lymphocyte Activation; Male; Middle Aged; Molecular Sequence Data; Muromonab-CD3; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Quinones; Rifabutin; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Type C Phospholipases | 1995 |
Comparison of the anti-inflammatory activity and gastrointestinal irritancy of nabumetone, ibuprofen, and diclofenac in rats following chronic administration.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Carrageenan; Cecum; Diclofenac; Digestive System; Drug Administration Schedule; Gastric Mucosa; Gastrointestinal Diseases; Haptoglobins; Hemoglobins; Ibuprofen; Ileum; Male; Nabumetone; Rats; Rats, Wistar | 1994 |
The determination of non-steroidal antiinflammatory drugs in pharmaceuticals by capillary zone electrophoresis and micellar electrokinetic capillary chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Buffers; Calibration; Chemistry, Pharmaceutical; Chromatography; Diclofenac; Dosage Forms; Electrophoresis; Ibuprofen; Indomethacin; Ketoprofen; Micelles; Piroxicam; Reference Standards; Regression Analysis; Reproducibility of Results | 1994 |
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygenase Inhibitors; Diclofenac; Edema; Fever; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Nitrobenzenes; Pain; Phenylpropionates; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides | 1993 |
Do non-steroidal anti-inflammatory drugs have an effect on gastric cell turnover?
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Bromodeoxyuridine; Cell Division; Diclofenac; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Immunohistochemistry; Indomethacin; Mefenamic Acid; Naproxen; Pyloric Antrum | 1995 |
Comparison of the efficacy of intrauterine diclofenac and ibuprofen pellets as adjuvants to quinacrine nonsurgical female sterilization.
Topics: Diclofenac; Female; Humans; Ibuprofen; India; Pregnancy; Quinacrine; Sterilization, Reproductive; Uterus | 1995 |
Assessment of gentamicin-induced nephrotoxicity in rats treated with low doses of ibuprofen and diclofenac sodium.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Blood Urea Nitrogen; Creatinine; Diclofenac; Drug Synergism; Gentamicins; Ibuprofen; Kidney; Male; Organ Size; Phospholipids; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Time Factors | 1996 |
Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dermatitis, Phototoxic; Diclofenac; Erythrocytes; Hemolysis; Humans; Ibuprofen; In Vitro Techniques; Ketoprofen; Light; Naproxen; Phenylbutazone; Photosensitizing Agents; Piroxicam; Propionates | 1996 |
Nonsteroidal antiinflammatory drug modulation of behavioral responses to intrathecal N-methyl-D-aspartate, but not to substance P and amino-methyl-isoxazole-propionic acid in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Diclofenac; Ibuprofen; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Stereoisomerism; Substance P | 1996 |
Papillary necrosis in a ballet dancer with no history of analgesic abuse.
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Ibuprofen; Kidney Papillary Necrosis; Phenacetin; Substance-Related Disorders | 1996 |
Immunochemical identification of mouse hepatic protein adducts derived from the nonsteroidal anti-inflammatory drugs diclofenac, sulindac, and ibuprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Ibuprofen; Immune Sera; Immunoblotting; Immunochemistry; Liver; Mice; Mice, Inbred Strains; Proteins; Rabbits; Sulindac | 1997 |
Effects of the combined oral administration of NSAIDs and dextromethorphan on behavioral symptoms indicative of arthritic pain in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Behavior, Animal; Dextromethorphan; Diclofenac; Drug Interactions; Drug Therapy, Combination; Etodolac; Ibuprofen; Injections, Intraperitoneal; Male; Naproxen; Pain; Piroxicam; Rats; Rats, Sprague-Dawley | 1996 |
Effect of ibuprofen and diclofenac sodium on experimental would healing.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Ibuprofen; Male; Rats; Wound Healing | 1997 |
Development of an HPLC assay to study the effect of endogenous and exogenous substances on heat-induced aggregation of human serum albumin.
Topics: Acids, Acyclic; Albumins; Anti-Inflammatory Agents, Non-Steroidal; Bilirubin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dicarboxylic Acids; Diclofenac; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Humans; Ibuprofen; In Vitro Techniques; Naproxen; Nephelometry and Turbidimetry; Protein Denaturation; Serum Albumin; Sodium Chloride | 1998 |
Correlation of in vitro and in vivo testing.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Biomedical Engineering; Diclofenac; Drug Evaluation; Drug Evaluation, Preclinical; Female; Humans; Ibuprofen; In Vitro Techniques; Skin; Sunscreening Agents; Ultraviolet Rays | 1998 |
Influence of acute uraemia on percutaneous absorption of nonsteroidal anti-inflammatory drugs.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Indomethacin; Male; Rats; Rats, Wistar; Skin Absorption; Uremia | 1998 |
Identification of residues 286 and 289 as critical for conferring substrate specificity of human CYP2C9 for diclofenac and ibuprofen.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Activation; Escherichia coli; Humans; Hydroxylation; Ibuprofen; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Protein Binding; Recombinant Fusion Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Tolbutamide | 1998 |
Influence of nonsteroidal anti-inflammatory drugs on calcium efflux in isolated rat renal cortex mitochondria and aspects of the mechanisms involved.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cyclosporine; Diclofenac; Dipyrone; Ibuprofen; In Vitro Techniques; Ion Transport; Kidney Cortex; Male; Mefenamic Acid; Mitochondria; NAD; NADP; Oxidation-Reduction; Piroxicam; Rats; Rats, Wistar; Salicylic Acid | 1998 |
Low-dose diclofenac, naproxen, and ibuprofen cohort study.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cohort Studies; Diclofenac; Dose-Response Relationship, Drug; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Female; Gastrointestinal Hemorrhage; Hematologic Diseases; Humans; Ibuprofen; Male; Middle Aged; Naproxen | 1999 |
Cleavage of tertiary amidomethyl ester prodrugs of carboxylic acids by rat liver homogenates.
Topics: Amides; Animals; Benzoic Acid; Carboxylic Acids; Clofibric Acid; Diclofenac; Drug Interactions; Esters; Hydrolases; Hydrolysis; Ibuprofen; In Vitro Techniques; Liver; Male; Naproxen; Physostigmine; Proadifen; Probenecid; Prodrugs; Rats; Rats, Sprague-Dawley; Refractometry; Solubility; Structure-Activity Relationship; Time Factors; Valproic Acid | 1999 |
Pharmacoepidemiology of non-steroidal anti-inflammatory drug use in Nottingham general practices.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Prescriptions; Family Practice; Humans; Ibuprofen; Inflammation; Medical Records Systems, Computerized; Middle Aged; Naproxen; Patient Compliance; Pharmacoepidemiology; United Kingdom | 2000 |
Ibuprofen versus other non-steroidal anti-inflammatory drugs: use in general practice and patient perception.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Prescriptions; Humans; Ibuprofen; Medical Records Systems, Computerized; Middle Aged; Naproxen; Patient Satisfaction; Surveys and Questionnaires; United Kingdom | 2000 |
Preference for nonsteroidal antiinflammatory drugs versus acetaminophen and concomitant use of both types of drugs in patients with osteoarthritis.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Data Collection; Diclofenac; Female; Humans; Ibuprofen; Male; Naproxen; Osteoarthritis; Patient Satisfaction; Self Administration; Surveys and Questionnaires | 2000 |
[Topical administration is better than oral administration].
Topics: Administration, Oral; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Humans; Ibuprofen; Randomized Controlled Trials as Topic; Treatment Outcome | 2001 |
In vitro effect of different non-steroidal anti-inflammatory drugs on human polymorphonuclear leukocyte activity measured by luminol-dependent chemiluminescence of the whole blood.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Barium Sulfate; Blood Group Antigens; Contrast Media; Diclofenac; Drug Evaluation, Preclinical; Erythrocyte Indices; Female; Hemoglobins; Humans; Ibuprofen; Indicators and Reagents; Indomethacin; Leukocyte Count; Luminescent Measurements; Luminol; Male; Middle Aged; Neutrophils | 2001 |
[Two complex suicidal poisonings with drugs and their medicolegal aspects].
Topics: Adult; Atenolol; Chromatography, High Pressure Liquid; Diclofenac; Estazolam; Fatal Outcome; Female; Humans; Ibuprofen; Illicit Drugs; Ketoprofen; Male; Metronidazole; Naproxen; Poland; Suicide, Attempted; Theophylline; Tolperisone | 2001 |
[Effects of lysine clonixinate on platelet function. Comparison with other non-steroidal anti-inflammatory agents].
Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Clonixin; Diclofenac; Flow Cytometry; Humans; Ibuprofen; Lysine; Male; P-Selectin; Platelet Aggregation; Platelet Count; Platelet Function Tests | 2001 |
Intracerebroventricular interleukin-1beta impairs clearance of tumor cells from the lungs: role of brain prostaglandins.
Topics: Adenocarcinoma; Animals; Brain; Cyclooxygenase Inhibitors; Diclofenac; Ibuprofen; Injections, Intraventricular; Interleukin-1; Lung Neoplasms; Male; Naltrexone; Narcotic Antagonists; Neoplasm Invasiveness; Neural Pathways; Norepinephrine; Prostaglandins; Rats; Rats, Inbred F344 | 2001 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Etodolac; Humans; Ibuprofen; Indomethacin; Ketorolac; Lactones; Nabumetone; Naproxen; Pain, Postoperative; Piroxicam; Pyrazoles; Sulfonamides; Sulfones; Time Factors | 2001 |
Contribution of nonsteroidal anti-inflammatory drugs to deaths associated with peptic ulcer disease: a prospective toxicological analysis of autopsy blood samples.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Chromatography, High Pressure Liquid; Diclofenac; Female; Humans; Ibuprofen; Intestinal Mucosa; Ketoprofen; Male; Middle Aged; Peptic Ulcer; Prospective Studies; Survival Rate | 2001 |
Comparison of cardiovascular thrombotic events in patients with osteoarthritis treated with rofecoxib versus nonselective nonsteroidal anti-inflammatory drugs (ibuprofen, diclofenac, and nabumetone).
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cardiovascular Diseases; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diclofenac; Female; Humans; Ibuprofen; Incidence; Lactones; Male; Middle Aged; Nabumetone; Osteoarthritis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Risk; Sulfones; Thrombosis; Treatment Outcome | 2002 |
Gastrointestinal medications and procedures in osteoarthritis patients treated with rofecoxib compared with nonselective NSAIDs.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Lactones; Male; Middle Aged; Nabumetone; Osteoarthritis; Randomized Controlled Trials as Topic; Sulfones | 2001 |
A comparison of adverse renovascular experiences among osteoarthritis patients treated with rofecoxib and comparator non-selective non-steroidal anti-inflammatory agents.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Edema; Female; Humans; Hypertension; Ibuprofen; Isoenzymes; Lactones; Male; Membrane Proteins; Nabumetone; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Renal Circulation; Safety; Sulfones | 2002 |
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Diclofenac; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Epithelial Cells; Fallopian Tubes; Female; Histamine; Humans; Ibuprofen; Indomethacin; Inflammation Mediators; Muscle Contraction; Muscle, Smooth; Naproxen; Pelvic Pain; Platelet Activating Factor | 2002 |
The effect of nonsteroidal antiinflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Cycle; Cell Division; Diclofenac; Fibrosarcoma; Flurbiprofen; Ibuprofen; In Vitro Techniques; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Survival Rate; Tumor Cells, Cultured | 2002 |
Digging for data from the COX-2 trials.
Topics: Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Peptic Ulcer; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Treatment Outcome | 2002 |
Are selective COX 2 inhibitors superior to traditional NSAIDs? Pharmacia's response to editorial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Diclofenac; Drug Therapy, Combination; Humans; Ibuprofen; Peptic Ulcer; Pyrazoles; Sulfonamides | 2002 |
Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Gemfibrozil; Hydrogen-Ion Concentration; Hydroxides; Ibuprofen; Naproxen; ortho-Aminobenzoates; Phenylacetates; Valproic Acid | 2001 |
[Analgesic in osteoporosis. Why so conservative with dosage?].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Humans; Ibuprofen; Lactones; Middle Aged; Osteoporosis; Pyrazoles; Risk Factors; Sulfonamides; Sulfones | 2002 |
Nonsteroidal anti-inflammatory drugs overdosage--the cause or the consequence of necrotizing fasciitis?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Fasciitis, Necrotizing; Female; Humans; Ibuprofen | 2003 |
Short-term tests with a pilot sewage plant and biofilm reactors for the biological degradation of the pharmaceutical compounds clofibric acid, ibuprofen, and diclofenac.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Biofilms; Bioreactors; Clofibric Acid; Diclofenac; Hypolipidemic Agents; Ibuprofen; Models, Theoretical; Refuse Disposal; Sewage; Water Pollutants, Chemical; Water Purification | 2003 |
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit vascular smooth muscle cell proliferation via differential effects on the cell cycle.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Cell Division; Cell Line; Diclofenac; Dose-Response Relationship, Drug; Flow Cytometry; Ibuprofen; Indomethacin; Muscle, Smooth, Vascular; Rats; Sodium Salicylate; Sulindac | 2003 |
Rofecoxib in rheumatoid arthritis: new indication. No better that other NSAIDS.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Contraindications; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Lactones; Naproxen; Sulfonamides; Treatment Outcome; United States | 2003 |
[Gastrointestinal hemorrhages as complications of gastropathies associated with intake of nonsteroidal anti-inflammatory drugs].
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Duodenal Ulcer; Duodenoscopy; Esophageal Diseases; Esophagoscopy; Female; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Indomethacin; Male; Peptic Ulcer Hemorrhage; Retrospective Studies; Stomach Ulcer | 2003 |
Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Ibuprofen; Isoenzymes; Ketorolac; Male; Membrane Proteins; Monosaccharide Transport Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Sulfonamides; Time Factors; Trans-Activators; Transcription Factors; Up-Regulation; Vascular Endothelial Growth Factor A | 2003 |
Antinociceptive synergy, additivity, and subadditivity with combinations of oral glucosamine plus nonopioid analgesics in mice.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Disease Models, Animal; Drug Therapy, Combination; Glucosamine; Ibuprofen; Indomethacin; Ketoprofen; Mice; Pain; Piroxicam | 2003 |
Persistence with COX-2 inhibitors in managed care: an analysis of claims data.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Utilization Review; Female; Health Care Costs; Humans; Ibuprofen; Insurance Claim Review; Isoenzymes; Lactones; Male; Managed Care Programs; Membrane Proteins; Middle Aged; Naproxen; Patient Compliance; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Regression Analysis; Sulfonamides; Sulfones; United States | 2003 |
Potential interaction between acenocoumarol and diclofenac, naproxen and ibuprofen and role of CYP2C9 genotype.
Topics: Acenocoumarol; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Chi-Square Distribution; Cohort Studies; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; Drug Interactions; Female; Genotype; Humans; Ibuprofen; International Normalized Ratio; Male; Middle Aged; Naproxen; Retrospective Studies; Sex Factors; Time Factors; Warfarin | 2004 |
Circular dichroism simulation shows a site-II-to-site-I displacement of human serum albumin-bound diclofenac by ibuprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; Circular Dichroism; Computer Simulation; Diclofenac; Humans; Ibuprofen; Models, Chemical; Protein Binding; Serum Albumin | 2000 |
Application of capillary electrophoresis with different sample stacking strategies for the determination of a group of nonsteroidal anti-inflammatory drugs in the low microg x L(-1) concentration range.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrophoresis, Capillary; Fenoprofen; Ibuprofen; Ketoprofen; Naproxen; Water | 2004 |
Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9).
Topics: Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Base Sequence; Binding Sites; Cytochrome P-450 CYP2C9; Diclofenac; Escherichia coli; Gene Expression; Hemeproteins; Holoenzymes; Humans; Ibuprofen; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Naproxen; Peptide Fragments; Recombinant Proteins; Sequence Homology, Nucleic Acid; Substrate Specificity | 2004 |
Nonsteroidal anti-inflammatory drug-induced liver injury: a case-control study in primary care.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cholestasis; Diclofenac; Drug Therapy, Combination; Female; Flurbiprofen; Hepatocytes; Humans; Ibuprofen; Ketoprofen; Liver; Male; Meloxicam; Middle Aged; Niflumic Acid; Primary Health Care; Salicylates; Sex Distribution; Statistics, Nonparametric; Thiazines; Thiazoles; Time Factors | 2004 |
Nonsteroidal antiinflammatory-induced acute renal failure detected on bone scintigraphy.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Diclofenac; Humans; Ibuprofen; Low Back Pain; Male; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate | 2004 |
Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis.
Topics: Activating Transcription Factor 4; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Northern; Celecoxib; Cell Line; Cell Survival; Cells, Cultured; Diclofenac; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Gastric Mucosa; Genes, Reporter; Guinea Pigs; Heat-Shock Proteins; Hydrogen Peroxide; Ibuprofen; Immunoblotting; Indomethacin; Luciferases; Macrophages; Microscopy, Fluorescence; Molecular Chaperones; Plasmids; Pyrazoles; Regulatory Factor X Transcription Factors; RNA, Messenger; Sulfonamides; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; X-Box Binding Protein 1 | 2004 |
Nonsteroidal antiinflammatory drugs and the risk of myocardial infarction in the general population.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiotonic Agents; Case-Control Studies; Cohort Studies; Comorbidity; Coronary Disease; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Drug Synergism; Drug Utilization; Female; Follow-Up Studies; Humans; Ibuprofen; Lactones; Male; Middle Aged; Myocardial Infarction; Naproxen; Odds Ratio; Risk Factors; Spain; Sulfones | 2004 |
Awareness and frequency of potential side effects on nonsteroidal anti-inflammatory drugs among the Jordanian patient population.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Awareness; Diclofenac; Drug Utilization; Female; Gastrointestinal Diseases; Health Surveys; Humans; Ibuprofen; Jordan; Male; Middle Aged; Needs Assessment; Patient Education as Topic | 2004 |
Interactions between aspirin and COX-2 inhibitors or NSAIDs in a rat thrombosis model.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Flurbiprofen; Ibuprofen; Isoenzymes; Lactones; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulfones; Thrombosis | 2004 |
Carbamazepine, diclofenac, ibuprofen and bezafibrate--investigations on the behaviour of selected pharmaceuticals during wastewater treatment.
Topics: Bezafibrate; Carbamazepine; Diclofenac; Europe; Ibuprofen; Pharmaceutical Preparations; Risk Assessment; Sewage; Time Factors; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2004 |
Evidence in practice--number 3: Cox 2 inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Evidence-Based Medicine; Humans; Ibuprofen; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Stomach Ulcer | 2004 |
Sulfone COX-2 inhibitors increase susceptibility of human LDL and plasma to oxidative modification: comparison to sulfonamide COX-2 inhibitors and NSAIDs.
Topics: Animals; Antioxidants; Celecoxib; Cholesterol, LDL; Chromans; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Isoprostanes; Isoxazoles; Lactones; Meloxicam; Naproxen; Oxidation-Reduction; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2004 |
Transdermal self-permeation enhancement of ibuprofen.
Topics: Administration, Cutaneous; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Diclofenac; Epidermis; Humans; Hydrogen-Ion Concentration; Ibuprofen; In Vitro Techniques; Membranes, Artificial; Pharmaceutical Solutions; Rats; Rats, Sprague-Dawley; Skin Absorption; Solubility; Surface Tension; Surface-Active Agents; Thermodynamics | 2004 |
Acid-induced pain and its modulation in humans.
Topics: Acid Sensing Ion Channels; Administration, Cutaneous; Adult; Amiloride; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Diclofenac; Female; Forearm; Hot Temperature; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Hyperalgesia; Ibuprofen; Injections, Subcutaneous; Ion Channels; Iontophoresis; Male; Membrane Proteins; Middle Aged; Nerve Tissue Proteins; Pain; Pain Measurement; Pain Threshold; Refractory Period, Electrophysiological; Single-Blind Method; Sodium Channels; TRPV Cation Channels | 2004 |
[Gastrointestinal complications under NSAID treatment in the doctor's office].
Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Diclofenac; Dose-Response Relationship, Drug; Dyspepsia; Endoscopy, Digestive System; Humans; Ibuprofen; Lactones; Peptic Ulcer; Smoking; Spondylitis; Sulfones | 2004 |
Tracking acidic pharmaceuticals, caffeine, and triclosan through the wastewater treatment process.
Topics: Caffeine; Diclofenac; Ibuprofen; Ketoprofen; Meclofenamic Acid; Models, Chemical; Naproxen; Pharmaceutical Preparations; Triclosan; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Patients exposed to rofecoxib and celecoxib have different odds of nonfatal myocardial infarction.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bias; Case-Control Studies; Celecoxib; Confounding Factors, Epidemiologic; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Lactones; Male; Middle Aged; Myocardial Infarction; Naproxen; Odds Ratio; Pyrazoles; Risk Factors; Sulfonamides; Sulfones | 2005 |
Cellular mechanisms of acetaminophen: role of cyclo-oxygenase.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cell Line; Cyclooxygenase Inhibitors; Diclofenac; Enzyme Activation; Humans; Ibuprofen; Indomethacin; Lactones; Lung; Naproxen; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; Sulfones; tert-Butylhydroperoxide; Transcription, Genetic | 2005 |
Measuring the mass of an electron by LC/TOF-MS: a study of "twin ions".
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Carbon Dioxide; Chromatography, Liquid; Diclofenac; Electrons; Formates; Ibuprofen; Ions; Naproxen; Protons; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Compaction, compression and drug release properties of diclofenac sodium and ibuprofen pellets comprising xanthan gum as a sustained release agent.
Topics: Delayed-Action Preparations; Diclofenac; Ibuprofen; Polysaccharides, Bacterial; Solubility; Technology, Pharmaceutical | 2005 |
Occurrence of several acidic drugs in sewage treatment plants in Switzerland and risk assessment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Clofibric Acid; Diclofenac; Environmental Monitoring; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Mefenamic Acid; No-Observed-Adverse-Effect Level; Risk Assessment; Sewage; Switzerland; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Determination of sorption coefficients of pharmaceutically active substances carbamazepine, diclofenac, and ibuprofen, in sandy sediments.
Topics: Adsorption; Berlin; Carbamazepine; Carbon; Diclofenac; Geologic Sediments; Ibuprofen; Octanols; Organic Chemicals; Silicon Dioxide; Thermodynamics; Water Pollutants, Chemical | 2005 |
Occurrence of acidic pharmaceuticals in raw and treated sewages and in receiving waters.
Topics: Bezafibrate; Diclofenac; Environmental Pollutants; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Molecular Structure; Naproxen; Sewage; Water | 2005 |
Occurrence and fate of pharmaceutically active compounds in the environment, a case study: Höje River in Sweden.
Topics: Adrenergic beta-Antagonists; Anti-Bacterial Agents; Carbamazepine; Diclofenac; Environmental Monitoring; Humans; Ibuprofen; Osmolar Concentration; Pharmaceutical Preparations; Rivers; Sewage; Sweden; Water Pollutants, Chemical; Water Pollution, Chemical | 2005 |
Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and their occurrence in municipal wastewater treated by a membrane bioreactor.
Topics: Aerobiosis; Amides; Bezafibrate; Biodegradation, Environmental; Bioreactors; Cities; Diclofenac; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Sewage; Spectrometry, Mass, Electrospray Ionization; Time Factors; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Development and application of a new on-line SPE system combined with LC-MS/MS detection for high throughput direct analysis of pharmaceutical compounds in plasma.
Topics: Chemical Fractionation; Chromatography, High Pressure Liquid; Diclofenac; Ibuprofen; Ketoconazole; Mass Spectrometry; Online Systems; Pharmaceutical Preparations; Propranolol; Reproducibility of Results | 2005 |
Ultrafiltration behavior of selected pharmaceuticals on natural and synthetic membranes in the presence of humic-rich hydrocolloids.
Topics: Animals; Carbamazepine; Cattle; Cell Membrane; Cellulose; Colloids; Diclofenac; Humic Substances; Ibuprofen; Intestinal Mucosa; Membranes, Artificial; Molecular Structure; Pharmaceutical Preparations; Polymers; Sulfamethoxazole; Sulfones; Ultrafiltration | 2005 |
Is there an association between the use of different types of nonsteroidal antiinflammatory drugs and radiologic progression of osteoarthritis? The Rotterdam Study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Disease Progression; Female; Follow-Up Studies; Humans; Ibuprofen; Logistic Models; Male; Middle Aged; Naproxen; Netherlands; Osteoarthritis, Hip; Osteoarthritis, Knee; Pharmacies; Piroxicam; Radiography; Risk Factors | 2005 |
Mobility of pharmaceuticals carbamazepine, diclofenac, ibuprofen, and propyphenazone in miscible-displacement experiments.
Topics: Adsorption; Antipyrine; Carbamazepine; Diclofenac; Geologic Sediments; Ibuprofen; Silicon Dioxide; Waste Disposal, Fluid; Water Movements; Water Pollutants, Chemical; Water Supply | 2006 |
Efficacy and safety of acupuncture for the treatment of non-specific acute low back pain: a randomised controlled multicentre trial protocol [ISRCTN65814467].
Topics: Acetaminophen; Acupuncture; Acute Disease; Adult; Amitriptyline; Analgesics; Bayes Theorem; Clinical Protocols; Cost-Benefit Analysis; Diclofenac; Humans; Ibuprofen; Low Back Pain; Multicenter Studies as Topic; Pain Measurement; Patient Satisfaction; Prospective Studies; Randomized Controlled Trials as Topic; Research Design; Sample Size; Treatment Outcome | 2006 |
Electrodialysis for recovering salts from a urine solution containing micropollutants.
Topics: Carbamazepine; Dialysis; Diclofenac; Electrochemistry; Ibuprofen; Propranolol; Salts; Water Pollutants, Chemical | 2006 |
Risk of death or reinfarction associated with the use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs after acute myocardial infarction.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Confidence Intervals; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Denmark; Diclofenac; Dose-Response Relationship, Drug; Female; Humans; Ibuprofen; Lactones; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Patient Readmission; Proportional Hazards Models; Pyrazoles; Recurrence; Registries; Retrospective Studies; Risk Factors; Sulfonamides; Sulfones | 2006 |
Quantitative assessment of the gastrointestinal and cardiovascular risk-benefit of celecoxib compared to individual NSAIDs at the population level.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Celecoxib; Computer Simulation; Coronary Disease; Cyclooxygenase Inhibitors; Diclofenac; Female; Heart Failure; Humans; Ibuprofen; Male; Middle Aged; Models, Statistical; Naproxen; Peptic Ulcer; Population Surveillance; Pyrazoles; Risk Assessment; Risk Factors; Stroke; Sulfonamides; United States | 2007 |
Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Lactones; Male; Multivariate Analysis; Myocardial Infarction; Naproxen; Pyrazoles; Rheumatic Diseases; Risk Assessment; Risk Factors; Sulfonamides; Sulfones | 2006 |
Improving the loading and release of NSAIDs from pHEMA hydrogels by copolymerization with functionalized monomers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Delivery Systems; Hydrogels; Ibuprofen; Polyhydroxyethyl Methacrylate; Solubility | 2007 |
Association between nonnaproxen NSAIDs, COX-2 inhibitors and hospitalization for acute myocardial infarction among the elderly: a retrospective cohort study.
Topics: Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cohort Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Prescriptions; Drug Utilization; Female; Hospitalization; Humans; Ibuprofen; Lactones; Male; Myocardial Infarction; Product Surveillance, Postmarketing; Proportional Hazards Models; Pyrazoles; Quebec; Retrospective Studies; Sex Factors; Sulfonamides; Sulfones | 2007 |
Silicone rod extraction of pharmaceuticals from water.
Topics: Antipyrine; Carbamazepine; Diclofenac; Ibuprofen; Pharmaceutical Preparations; Silicones; Time Factors; Water | 2007 |
Effect of different cyclooxygenase inhibitors on gastric adaptive cytoprotection induced by 20% ethanol.
Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytoprotection; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gastric Acid; Gastric Mucosa; Ibuprofen; Irritants; Male; Meloxicam; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyrazoles; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides; Thiazines; Thiazoles | 2007 |
High-performance liquid chromatography and pharmacokinetics of aceclofenac in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Diclofenac; Ethylamines; Hydrogen-Ion Concentration; Ibuprofen; Methanol; Models, Chemical; Rats; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2007 |
Heat injury-induced drop of the noxious heat threshold measured with an increasing-temperature water bath: a novel rat thermal hyperalgesia model.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Diclofenac; Dose-Response Relationship, Drug; Female; Hindlimb; Hot Temperature; Hyperalgesia; Ibuprofen; Injections; Injections, Intraperitoneal; Models, Animal; Morphine; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Reproducibility of Results; Thermosensing; Time Factors | 2007 |
Micellar solubilization of selected non-steroidal therapeutic agents by new surface-active agents of the class of the products of oxyethylation of ursodeoxycholic acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Ketoprofen; Micelles; Naproxen; Pharmaceutical Preparations; Solubility; Solutions; Surface-Active Agents; Ursodeoxycholic Acid; Viscosity | 2006 |
Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.
Topics: Acylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Chromatography, Liquid; Cyclooxygenase Inhibitors; Diclofenac; Drug Stability; Flufenamic Acid; Glucuronides; Half-Life; Ibuprofen; Indomethacin; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mefenamic Acid; Molecular Structure; Rats; Rats, Sprague-Dawley; Stereoisomerism; Technology, Pharmaceutical; Tolmetin | 2007 |
Elimination of selected acidic pharmaceuticals from municipal wastewater by an activated sludge system and membrane bioreactors.
Topics: Bioreactors; Diclofenac; Ibuprofen; Ketoprofen; Membranes, Artificial; Molecular Weight; Pharmaceutical Preparations; Sewage; Water Purification | 2007 |
Liquid chromatographic analysis of certain commercial formulations for non-opioid analgesics.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Crystallization; Diclofenac; Drug Stability; Ibuprofen; Pharmaceutical Preparations; Spectrophotometry, Ultraviolet; Time Factors | 2007 |
Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Case-Control Studies; Celecoxib; Cytochrome P-450 CYP2C9; Diclofenac; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Odds Ratio; Peptic Ulcer; Peptic Ulcer Hemorrhage; Piroxicam; Polymorphism, Single Nucleotide; Pyrazoles; Risk Assessment; Risk Factors; Sulfonamides | 2007 |
Treating osteoarthritis in the elderly: should recent data on NSAIDs change our way of practice?
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Databases, Factual; Diclofenac; Gastrointestinal Diseases; Humans; Ibuprofen; Kidney Diseases; Lactones; Myocardial Infarction; Osteoarthritis; Retrospective Studies; Sulfones | 2007 |
Photocatalytic degradation of non-steroidal anti-inflammatory drugs with TiO2 and simulated solar irradiation.
Topics: Aliivibrio fischeri; Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Diclofenac; Ibuprofen; Luminescence; Naproxen; Photolysis; Sunlight; Titanium; Water Pollutants, Chemical | 2008 |
Etoricoxib: new drug. Avoid using cox-2 inhibitors for pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Gastrointestinal Diseases; Gout; Humans; Ibuprofen; Naproxen; Pain; Pyridines; Sulfones | 2007 |
In vitro phonophoresis: effect of ultrasound intensity and mode at high frequency on NSAIDs transport across cellulose and rabbit skin membranes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Diclofenac; Diffusion; Ibuprofen; In Vitro Techniques; Membranes, Artificial; Pharmaceutical Vehicles; Phonophoresis; Piroxicam; Rabbits; Skin Absorption; Ultrasonics | 2008 |
Cyclooxygenase-2 inhibitors and most traditional nonsteroidal anti-inflammatory drugs cause similar moderately increased risks of cardiovascular disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Humans; Ibuprofen; Meta-Analysis as Topic; Myocardial Infarction; Naproxen; Risk | 2008 |
Mechanisms of non-steroid anti-inflammatory drugs action on ASICs expressed in hippocampal interneurons.
Topics: Acid Sensing Ion Channels; Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Cytoprotection; Diclofenac; Drug Interactions; Hippocampus; Hydrogen-Ion Concentration; Ibuprofen; Interneurons; Membrane Potentials; Nerve Tissue Proteins; Neuroprotective Agents; Organ Culture Techniques; Protons; Rats; Sodium Channels | 2008 |
Identification and quantification of ibuprofen, naproxen, ketoprofen and diclofenac present in waste-waters, as their trimethylsilyl derivatives, by gas chromatography mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gas Chromatography-Mass Spectrometry; Hungary; Ibuprofen; Ketoprofen; Naproxen; Trimethylsilyl Compounds; Waste Disposal, Fluid; Water Pollutants, Chemical | 2008 |
Does the varied use of NSAIDs explain the differences in the risk of myocardial infarction?
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Administration Schedule; Epidemiologic Methods; Female; Humans; Ibuprofen; Male; Middle Aged; Myocardial Infarction; Naproxen; Sex Factors; Time Factors | 2008 |
Prescriptions of NSAIDs to patients undergoing third molar surgery : an observational, prospective, multicentre survey.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dental Health Surveys; Diclofenac; Drug Prescriptions; Female; Humans; Hungary; Ibuprofen; Italy; Ketoprofen; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Prospective Studies; Sulfonamides; Treatment Outcome | 2008 |
Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro.
Topics: Acetates; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Catalysis; Cyclopropanes; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Inhibitors; Genotype; Humans; Hydroxylation; Ibuprofen; Ketoconazole; Kinetics; Mephenytoin; Microsomes, Liver; Quinolines; Recombinant Proteins; Stereoisomerism; Sulfaphenazole; Sulfides; Tandem Mass Spectrometry | 2008 |
Preparation and characterization of silica xerogels as carriers for drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Delayed-Action Preparations; Diclofenac; Drug Carriers; Drug Compounding; Drug Stability; Gels; Hydrolysis; Ibuprofen; Microscopy, Electron, Scanning; Silanes; Silicon Dioxide; Solubility; Spectrophotometry, Ultraviolet; X-Ray Diffraction | 2008 |
Advances in stir bar sorptive extraction for the determination of acidic pharmaceuticals in environmental water matrices Comparison between polyurethane and polydimethylsiloxane polymeric phases.
Topics: Chromatography, High Pressure Liquid; Diclofenac; Dimethylpolysiloxanes; Gemfibrozil; Ibuprofen; Mefenamic Acid; Naproxen; Polyurethanes; Reproducibility of Results; Water Pollutants, Chemical; Water Purification | 2008 |
Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.
Topics: Antipyrine; Charcoal; Clofibric Acid; Diclofenac; Fenoprofen; Gemfibrozil; Halogenation; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Water Pollutants, Chemical; Water Purification; Water Supply | 2008 |
Post-operative pain: the impact of prescribing patterns on nurses' administration of analgesia.
Topics: Acetaminophen; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Codeine; Diclofenac; Drug Administration Schedule; Drug Prescriptions; Drug Utilization; Hospitals, Pediatric; Hospitals, Teaching; Humans; Ibuprofen; Nursing Assessment; Nursing Audit; Nursing Evaluation Research; Pain Measurement; Pain, Postoperative; Postoperative Care; Practice Patterns, Physicians'; Retrospective Studies | 2008 |
Morphological alteration in mitochondria following diclofenac and ibuprofen administration.
Topics: Animals; Cytochromes c; Cytosol; Diclofenac; Ibuprofen; Liver; Male; Microscopy, Electron, Transmission; Mitochondria; Rats; Rats, Sprague-Dawley | 2008 |
[Whipple's disease with normal duodenal histology and ankylosing spondylitis].
Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Ceftriaxone; Diagnosis, Differential; Diclofenac; DNA, Bacterial; Duodenum; Etanercept; Female; Humans; Ibuprofen; Immunoglobulin G; Polymerase Chain Reaction; Receptors, Tumor Necrosis Factor; Spondylitis, Ankylosing; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Tropheryma; Tumor Necrosis Factor-alpha; Whipple Disease | 2009 |
The membrane-activity of Ibuprofen, Diclofenac, and Naproxen: a physico-chemical study with lecithin phospholipids.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry; Calorimetry, Differential Scanning; Diclofenac; Dimyristoylphosphatidylcholine; Fluorescence Resonance Energy Transfer; Ibuprofen; Lecithins; Liposomes; Naproxen; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 2009 |
A retention-time-shift-tolerant background subtraction and noise reduction algorithm (BgS-NoRA) for extraction of drug metabolites in liquid chromatography/mass spectrometry data from biological matrices.
Topics: Algorithms; Animals; Chromatography, Liquid; Diclofenac; Humans; Ibuprofen; Loratadine; Male; Mass Spectrometry; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley | 2009 |
An in vitro biomarker approach for the evaluation of the ecotoxicity of non-steroidal anti-inflammatory drugs (NSAIDs).
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Comet Assay; Diclofenac; DNA Damage; Dose-Response Relationship, Drug; Dreissena; Hemocytes; Ibuprofen; In Vitro Techniques; Mutagenicity Tests; Neutral Red; Water Pollutants, Chemical | 2009 |
Non-steroidal anti-inflammatory drugs interact with testosterone glucuronidation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Genotype; Glucuronides; Glucuronosyltransferase; Humans; Ibuprofen; Liver; Microsomes; Minor Histocompatibility Antigens; Recombinant Proteins; Testosterone | 2009 |
Effects of non-steroidal anti-inflammatory drugs on Abeta deposition in Abeta(1-42) transgenic C. elegans.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Caenorhabditis elegans; Diclofenac; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Ibuprofen; Indomethacin; Microscopy, Confocal; Thiazoles | 2009 |
Determination of ibuprofen, ketoprofen, diclofenac and phenylbutazone in bovine milk by gas chromatography-tandem mass spectrometry.
Topics: Animals; Cattle; Diclofenac; Drug Residues; Food Analysis; Food Contamination; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Milk; Phenylbutazone; Sensitivity and Specificity; Tandem Mass Spectrometry | 2008 |
Multi-residue method for trace level determination of pharmaceuticals in solid samples using pressurized liquid extraction followed by liquid chromatography/quadrupole-linear ion trap mass spectrometry.
Topics: Acetaminophen; Atorvastatin; Chromatography, Liquid; Diclofenac; Geologic Sediments; Heptanoic Acids; Hot Temperature; Hydrochlorothiazide; Ibuprofen; Pharmaceutical Preparations; Pyrroles; Reference Standards; Reproducibility of Results; Rivers; Sewage; Solid Phase Extraction; Tandem Mass Spectrometry | 2009 |
HPLC determination of ibuprofen, diclofenac and salicylic acid using hollow fiber-based liquid phase microextraction (HF-LPME).
Topics: Chemical Fractionation; Chromatography, High Pressure Liquid; Diclofenac; Ibuprofen; Membranes, Artificial; Polypropylenes; Salicylic Acid; Time Factors | 2009 |
Degradation and adsorption of selected pharmaceuticals and personal care products (PPCPs) in agricultural soils.
Topics: Adsorption; Benzhydryl Compounds; Biodegradation, Environmental; Clofibric Acid; Diclofenac; Household Products; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenols; Soil; Soil Microbiology; Soil Pollutants; Triclosan | 2009 |
Cardiovascular risks of nonsteroidal antiinflammatory drugs in patients after hospitalization for serious coronary heart disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cohort Studies; Coronary Artery Disease; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Follow-Up Studies; Hospitalization; Humans; Ibuprofen; Incidence; Lactones; Male; Middle Aged; Myocardial Infarction; Naproxen; Outpatients; Pyrazoles; Retrospective Studies; Risk Factors; Stroke; Sulfonamides; Sulfones; Tennessee | 2009 |
Macroscopic small bowel mucosal injury caused by chronic nonsteroidal anti-inflammatory drugs (NSAID) use as assessed by capsule endoscopy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Cyclooxygenase 2 Inhibitors; Diclofenac; Duodenal Diseases; Duodenal Ulcer; Female; Humans; Ibuprofen; Intestinal Mucosa; Male; Middle Aged; Osteoarthritis; Peptic Ulcer Hemorrhage; Prospective Studies; Severity of Illness Index; Single-Blind Method; Stomach Diseases; Stomach Ulcer | 2010 |
Cationic surfactants-modified natural zeolites: improvement of the excipients functionality.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzalkonium Compounds; Cations; Cetrimonium; Cetrimonium Compounds; Chemistry, Pharmaceutical; Diclofenac; Excipients; Ibuprofen; Powders; Solubility; Surface-Active Agents; Zeolites | 2010 |
Second interlaboratory exercise on non-steroidal anti-inflammatory drug analysis in environmental aqueous samples.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry Techniques, Analytical; Diclofenac; Environmental Monitoring; Filtration; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Naproxen; Reproducibility of Results; Water Pollutants, Chemical; Water Purification | 2010 |
Should physicians stop prescribing nonsteroidal anti-inflammatory drugs for postoperative pericardial effusion?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiac Surgical Procedures; Diclofenac; Drug Administration Schedule; Humans; Ibuprofen; Pericardial Effusion | 2010 |
Physiological effects of diclofenac, ibuprofen and propranolol on Baltic Sea blue mussels.
Topics: Animals; Diclofenac; Ibuprofen; Mytilus edulis; Propranolol; Sewage; Water Pollutants, Chemical | 2010 |
Influence of ionic strength, anions, cations, and natural organic matter on the adsorption of pharmaceuticals to silica.
Topics: Adsorption; Anions; Carbamazepine; Cations; Diclofenac; Ibuprofen; Ketoprofen; Osmolar Concentration; Pharmaceutical Preparations; Silicon Dioxide; Soil | 2010 |
The role of the acquisition methods in the analysis of the non-steroidal anti-inflammatory drugs in Danube River by gas chromatography-mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Limit of Detection; Naproxen; Rivers; Water Pollutants, Chemical | 2010 |
Occurrence and transport of pharmaceuticals in a karst groundwater system affected by domestic wastewater treatment plants.
Topics: Biodegradation, Environmental; Diclofenac; Ecosystem; Environmental Monitoring; Germany; Ibuprofen; Water; Water Movements; Water Pollutants, Chemical; Water Purification; Water Supply | 2010 |
Phytoremediation of pharmaceuticals--preliminary study.
Topics: Acetaminophen; Biodegradation, Environmental; Diclofenac; Hydroponics; Ibuprofen; Pharmaceutical Preparations; Plants; Toxicity Tests | 2010 |
Determination of non-steroidal anti-inflammatory drugs in sewage sludge by direct hollow fiber supported liquid membrane extraction and liquid chromatography-mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Fractionation; Chromatography, Liquid; Diclofenac; Ibuprofen; Ketoprofen; Mass Spectrometry; Naproxen; Reproducibility of Results; Sewage | 2010 |
Capacity of a horizontal subsurface flow constructed wetland system for the removal of emerging pollutants: an injection experiment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Environmental Restoration and Remediation; Ibuprofen; Naproxen; Perfume; Tetrahydronaphthalenes; Waste Disposal, Fluid; Water Movements; Water Pollutants, Chemical; Wetlands | 2010 |
Stimuli-responsive networks grafted onto polypropylene for the sustained delivery of NSAIDs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Diclofenac; Hemolysis; Humans; Ibuprofen; Mice; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Thrombosis | 2011 |
Consumption of non-steroidal anti-inflammatory drugs in Serbia: a comparison with Croatia and Denmark during 2005-2008.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Croatia; Data Collection; Data Compression; Denmark; Diclofenac; Drug Utilization; Evidence-Based Medicine; Humans; Ibuprofen; Practice Patterns, Physicians'; Serbia | 2011 |
[Degradation of the mixed pharmaceuticals with low concentration in aqueous by solar/ferrioxalate system and process evaluation through toxicity bioassay].
Topics: Adsorption; Biological Assay; Bioreactors; Catalysis; Diclofenac; Hydrogen Peroxide; Ibuprofen; Medical Waste; Metronidazole; Oxalates; Photochemical Processes; Sulfamethoxazole; Sunlight; Waste Disposal, Fluid | 2010 |
Sorption and degradation of wastewater-associated non-steroidal anti-inflammatory drugs and antibiotics in soils.
Topics: Adsorption; Aerobiosis; Agricultural Irrigation; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Biodegradation, Environmental; Diclofenac; Ibuprofen; Naproxen; Soil; Soil Microbiology; Sulfamethoxazole; Trimethoprim; Water Pollutants, Chemical | 2011 |
Uptake from water, biotransformation, and biliary excretion of pharmaceuticals by rainbow trout.
Topics: Animals; Bile; Biotransformation; Bisoprolol; Carbamazepine; Diclofenac; Fresh Water; Ibuprofen; Naproxen; Oncorhynchus mykiss; Pharmaceutical Preparations; Water Pollutants, Chemical | 2011 |
NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Glomerulosclerosis, Focal Segmental; Ibuprofen; Kidney Glomerulus; Male; Rats; Rats, Sprague-Dawley; TRPC Cation Channels | 2011 |
Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: a nationwide cohort study.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Comorbidity; Contraindications; Cyclooxygenase 2 Inhibitors; Denmark; Diclofenac; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Myocardial Infarction; Naproxen; Prognosis; Proportional Hazards Models; Recurrence; Registries; Risk Factors | 2011 |
Harmful effects of NSAIDs among patients with hypertension and coronary artery disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Celecoxib; Confounding Factors, Epidemiologic; Coronary Artery Disease; Diclofenac; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Ibuprofen; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Myocardial Infarction; Naproxen; Odds Ratio; Proportional Hazards Models; Pyrazoles; Randomized Controlled Trials as Topic; Stroke; Sulfonamides; Verapamil | 2011 |
Luteinized unruptured follicle syndrome increased by inactive disease and selective cyclooxygenase 2 inhibitors in women with inflammatory arthropathies.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chi-Square Distribution; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Fertility; Humans; Ibuprofen; Infertility, Female; Inflammation; Norway; Ovarian Follicle; Ovulation; Pregnancy; Prospective Studies; Pyridines; Rheumatic Diseases; Risk Assessment; Risk Factors; Sulfones; Ultrasonography | 2011 |
Biotransformation of three pharmaceutical active compounds by the fungus Phanerochaete chrysosporium in a fed batch stirred reactor under air and oxygen supply.
Topics: Air; Anti-Inflammatory Agents; Batch Cell Culture Techniques; Biodegradation, Environmental; Bioreactors; Biotransformation; Diclofenac; Ibuprofen; Kinetics; Naproxen; Oxidation-Reduction; Oxygen; Phanerochaete; Water Pollutants, Chemical | 2012 |
Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC).
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Cell Line; CHO Cells; Cricetinae; Cricetulus; Cytochrome P-450 Enzyme System; Diclofenac; Epithelial Sodium Channels; Female; Ibuprofen; Kidney Tubules, Collecting; Mice; Models, Animal; Ovary; Patch-Clamp Techniques; Transfection | 2011 |
Structural properties of so-called NSAID-phospholipid-complexes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Diclofenac; Drug Compounding; Ibuprofen; Magnetic Resonance Spectroscopy; Molecular Structure; Piroxicam; Solvents; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2011 |
Can pharmaceuticals interfere with the synthesis of active androgens in male fish? An in vitro study.
Topics: Androgens; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Biomarkers; Carps; Clofibrate; Clofibric Acid; Diclofenac; Fibric Acids; Fluoxetine; Gemfibrozil; Ibuprofen; Male; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase; Testis; Water Pollutants, Chemical | 2011 |
Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish.
Topics: Animals; Atrazine; Benzhydryl Compounds; Carbamazepine; Diclofenac; Environmental Monitoring; Fishes; Fluoxetine; Gemfibrozil; Ibuprofen; Naproxen; Phenols; Solid Phase Extraction; Solid Phase Microextraction; Waste Disposal, Fluid; Water Pollutants, Chemical | 2011 |
Sub-lethal effects induced by a mixture of three non-steroidal anti-inflammatory drugs (NSAIDs) on the freshwater bivalve Dreissena polymorpha.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Survival; Comet Assay; Diclofenac; DNA Fragmentation; Dose-Response Relationship, Drug; Dreissena; Drug Combinations; Environmental Monitoring; Fresh Water; Ibuprofen; Immunodiffusion; Lysosomes; Micronucleus Tests; Mutagens; Neutral Red; Oxidative Stress; Oxidoreductases; Toxicity Tests; Water Pollutants, Chemical | 2012 |
Oral drug challenges in non-steroidal anti-inflammatory drug-induced urticaria, angioedema and anaphylaxis.
Topics: Acetaminophen; Adolescent; Adult; Aged; Anaphylaxis; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Urticaria; Young Adult | 2012 |
Ibuprofen or diclofenac is associated with more severe acute kidney injury in nephropathia epidemica.
Topics: Acetaminophen; Acute Kidney Injury; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Contraindications; Creatinine; Diclofenac; Dipyrone; Female; Germany; Hemorrhagic Fever with Renal Syndrome; Humans; Ibuprofen; Male; Middle Aged; Retrospective Studies; Severity of Illness Index | 2012 |
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts | 2012 |
[Bringing evidence to practice: obstacles and barriers].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Comparative Effectiveness Research; Conflict of Interest; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Approval; Drug Industry; Evidence-Based Medicine; Germany; Humans; Ibuprofen; Peptic Ulcer; Practice Guidelines as Topic; Publication Bias; Pyrazoles; Randomized Controlled Trials as Topic; Research Design; Research Support as Topic; Sulfonamides; Translational Research, Biomedical | 2011 |
Effect studies of human pharmaceuticals on Fucus vesiculosus and Gammarus spp.
Topics: Amphipoda; Animals; Diclofenac; Fucus; Humans; Ibuprofen; Oceans and Seas; Pharmaceutical Preparations; Propranolol; Sewage; Sweden; Water Pollutants, Chemical | 2012 |
Emerging pollutants in sewage, surface and drinking water in Galicia (NW Spain).
Topics: Atenolol; Benzophenones; Diclofenac; Drinking Water; Environmental Monitoring; Flame Retardants; Ibuprofen; Insecticides; Naproxen; Organophosphates; Plasticizers; Salicylic Acid; Seasons; Sewage; Spain; Sunscreening Agents; Triclosan; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Pollution, Chemical | 2012 |
Biofilm controlled sorption of selected acidic drugs on river sediments characterized by different organic carbon content.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biofilms; Carbon; Diclofenac; Gas Chromatography-Mass Spectrometry; Geologic Sediments; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Naproxen; Rivers; Water Pollutants, Chemical | 2012 |
Assessing the removal of pharmaceuticals and personal care products in a full-scale activated sludge plant.
Topics: Adsorption; Diclofenac; Flufenamic Acid; Gas Chromatography-Mass Spectrometry; Hydroxyzine; Ibuprofen; Indapamide; Perfume; Pharmaceutical Preparations; Sewage; Solid Phase Extraction; Ultraviolet Rays; Waste Disposal, Fluid; Water Pollutants, Chemical | 2012 |
Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.
Topics: Asparagine; Bacillus megaterium; Catalysis; Cytochrome P-450 Enzyme System; Diclofenac; Drug Discovery; Escherichia coli; Glutamine; Glycine; Histidine; Humans; Hydroxylation; Ibuprofen; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Tolbutamide | 2012 |
Assessing carrageenan-induced locomotor activity impairment in rats: comparison with evoked endpoint of acute inflammatory pain.
Topics: Acute Pain; Adrenergic Uptake Inhibitors; Amines; Amphetamine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Central Nervous System Stimulants; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Ibuprofen; Lameness, Animal; Male; Morphine; Motor Activity; Neuritis; Rats; Rats, Sprague-Dawley; Thiophenes | 2012 |
Determination of non-steroidal anti-inflammatory drugs in water samples by solid-phase microextraction based sol-gel technique using poly(ethylene glycol) grafted multi-walled carbon nanotubes coated fiber.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Diclofenac; Gels; Hydrogen-Ion Concentration; Ibuprofen; Nanotubes, Carbon; Naproxen; Polyethylene Glycols; Salts; Solid Phase Microextraction; Temperature; Time Factors; Water Pollutants, Chemical | 2012 |
Contrasting effects of diclofenac and ibuprofen on active imatinib uptake into leukaemic cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Diclofenac; Drug Interactions; Humans; Ibuprofen; Imatinib Mesylate; Inhibitory Concentration 50; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Organic Cation Transporter 1; Piperazines; Pyrimidines | 2012 |
Letter: Mucosal injury with exposure to low-dose nonsteroidals.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Female; Humans; Ibuprofen; Male | 2012 |
Batch versus continuous feeding strategies for pharmaceutical removal by subsurface flow constructed wetland.
Topics: Biodegradation, Environmental; Caffeine; Carbamazepine; Clofibric Acid; Diclofenac; Ibuprofen; Ketoprofen; Kinetics; Pharmaceutical Preparations; Waste Disposal, Fluid; Water Movements; Water Pollutants, Chemical; Wetlands | 2012 |
Bioavailability of pharmaceuticals in waters close to wastewater treatment plants: use of fish bile for exposure assessment.
Topics: Animals; Anti-Inflammatory Agents; Bile; Biological Availability; Carbamazepine; Chromatography, Liquid; Citalopram; Cyclohexanols; Diclofenac; Finland; Ibuprofen; Liver; Male; Naproxen; Oncorhynchus mykiss; Plasma; Venlafaxine Hydrochloride; Wastewater; Water Pollutants, Chemical | 2012 |
Identification of priority pharmaceuticals in the water environment of China.
Topics: Anti-Bacterial Agents; Cephalexin; China; Diclofenac; Drug Utilization; Drug-Related Side Effects and Adverse Reactions; Ecosystem; Environmental Monitoring; Erythromycin; Humans; Ibuprofen; Ketoconazole; Pharmaceutical Preparations; Rivers; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2012 |
Rejection of pharmaceuticals by forward osmosis membranes.
Topics: Carbamazepine; Diclofenac; Filtration; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Membranes, Artificial; Naproxen; Osmosis; Pharmaceutical Preparations; Water Pollutants, Chemical; Water Purification | 2012 |
Inhibition of mitochondrial complex I by various non-steroidal anti-inflammatory drugs and its protection by quercetin via a coenzyme Q-like action.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caco-2 Cells; Diclofenac; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electron Transport Complex I; Humans; Ibuprofen; Indomethacin; Mitochondria; Multienzyme Complexes; NAD; Piroxicam; Protective Agents; Quercetin; Rats; Ubiquinone | 2012 |
Acidic pharmaceuticals in domestic wastewater and receiving water from hyper-urbanization city of China (Shanghai): environmental release and ecological risk.
Topics: China; Cities; Diclofenac; Environmental Monitoring; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Urbanization; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Pollution, Chemical | 2013 |
Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calibration; Chromatography, High Pressure Liquid; Computing Methodologies; Diclofenac; Drug Combinations; Drug Stability; Expectorants; Guaifenesin; Ibuprofen; Limit of Detection; Methocarbamol; Muscle Relaxants, Central; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets; Technology, Pharmaceutical | 2012 |
Samter's triad and eicosanoid imbalance in children with recurrent nasal polyps.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Child; Diclofenac; Drug Hypersensitivity; Eicosanoids; Female; Humans; Ibuprofen; Leukocytes; Male; Nasal Polyps; Recurrence; Sensitivity and Specificity; Syndrome | 2012 |
Effect of particle size on the dissolution behaviors of poorly water-soluble drugs.
Topics: Chemistry, Pharmaceutical; Crystallization; Diclofenac; Hydrochlorothiazide; Ibuprofen; Kinetics; Models, Chemical; Particle Size; Solubility; Solvents; Surface Properties; Technology, Pharmaceutical; Water | 2012 |
The influence of the API properties on the ODTs manufacturing from co-processed excipient systems.
Topics: Administration, Oral; Chemistry, Pharmaceutical; Diclofenac; Diltiazem; Drug Compounding; Excipients; Hardness; Ibuprofen; Particle Size; Pressure; Solubility; Tablets; Technology, Pharmaceutical | 2012 |
Microneedle pretreatment enhances the percutaneous permeation of hydrophilic compounds with high melting points.
Topics: Acetaminophen; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Diclofenac; Female; Hydrophobic and Hydrophilic Interactions; Ibuprofen; In Vitro Techniques; Ketoprofen; Needles; Skin Absorption; Transition Temperature | 2012 |
Redox-sensitivity and mobility of selected pharmaceutical compounds in a low flow column experiment.
Topics: Carbamazepine; Denitrification; Diclofenac; Ibuprofen; Models, Chemical; Molecular Structure; Nitrates; Oxidation-Reduction; Pharmaceutical Preparations; Sulfamethoxazole; Water Pollutants, Chemical; Water Purification | 2012 |
Pre-concentration of non-steroidal anti-inflammatory drugs in water using dispersive liquid-liquid and single-drop microextraction with high-performance liquid chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Ibuprofen; Liquid Phase Microextraction; Naproxen; Water Pollutants, Chemical | 2012 |
Postoperative use of non-steroidal anti-inflammatory drugs in patients with anastomotic leakage requiring reoperation after colorectal resection: cohort study based on prospective data.
Topics: Aged; Anastomotic Leak; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Colorectal Neoplasms; Colorectal Surgery; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Postoperative Complications; Postoperative Period; Reoperation; Risk Factors | 2012 |
Use of nonsteroidal anti-inflammatory drugs among healthy people and specific cerebrovascular safety.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Cohort Studies; Denmark; Diclofenac; Humans; Ibuprofen; Intracranial Hemorrhages; Naproxen; Odds Ratio; Proportional Hazards Models; Risk; Stroke | 2014 |
Determination of non-steroidal anti-inflammatory drugs in urine by hollow-fiber liquid membrane-protected solid-phase microextraction based on sol-gel fiber coating.
Topics: 1-Octanol; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Diclofenac; Drug Stability; Humans; Ibuprofen; Limit of Detection; Linear Models; Nanotubes, Carbon; Naproxen; Phase Transition; Porosity; Reproducibility of Results; Sodium Chloride; Solid Phase Microextraction; Temperature | 2012 |
The anti-inflammatory drugs diclofenac, naproxen and ibuprofen are found in the bile of wild fish caught downstream of a wastewater treatment plant.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Cyprinidae; Diclofenac; Environmental Monitoring; Female; Ibuprofen; Lakes; Male; Naproxen; Waste Disposal, Fluid; Water Pollutants, Chemical | 2013 |
Human pharmaceuticals in wastewaters from urbanized areas of Argentina.
Topics: Argentina; Atenolol; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Cities; Diclofenac; Environmental Monitoring; Humans; Ibuprofen; Mass Spectrometry; Pharmaceutical Preparations; Wastewater; Water Pollutants, Chemical | 2013 |
Diclofenac enhances proinflammatory cytokine-induced aquaporin-4 expression in cultured astrocyte.
Topics: Animals; Aquaporin 4; Astrocytes; Blotting, Western; Cells, Cultured; Cyclooxygenase Inhibitors; Cytokines; Diclofenac; Gene Expression Regulation; Ibuprofen; Immunohistochemistry; Indomethacin; Inflammation Mediators; NF-kappa B; Rats; Rats, Wistar | 2013 |
Multi-phase partitioning, ecological risk and fate of acidic pharmaceuticals in a wastewater receiving river: the role of colloids.
Topics: Aquatic Organisms; Clofibric Acid; Colloids; Diclofenac; Ecotoxicology; Geologic Sediments; Ibuprofen; Ketoprofen; Models, Theoretical; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Wastewater; Water Pollutants, Chemical | 2013 |
Effects of ibuprofen, diclofenac, naproxen, and piroxicam on the course of pregnancy and pregnancy outcome: a prospective cohort study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Diclofenac; Female; Humans; Ibuprofen; Infant, Low Birth Weight; Infant, Newborn; Naproxen; Norway; Piroxicam; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Risk; Young Adult | 2013 |
The advantages and limitations of the analgesics available for control of postoperative pain after a dental procedure.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Codeine; Cyclooxygenase 2 Inhibitors; Dental Care; Diclofenac; Diflunisal; Drug Combinations; Humans; Ibuprofen; Narcotics; Oral Surgical Procedures; Pain, Postoperative; Tramadol | 2013 |
Numerical modelling and experimental investigation of drug release from layered silicone matrix systems.
Topics: Delayed-Action Preparations; Diclofenac; Drug Delivery Systems; Ibuprofen; Models, Theoretical; Reproducibility of Results; Silicones; Solubility | 2013 |
Application of nanofiltration for the removal of carbamazepine, diclofenac and ibuprofen from drinking water sources.
Topics: Carbamazepine; Diclofenac; Drinking Water; Filtration; Ibuprofen; Water Pollutants, Chemical; Water Purification; Water Supply | 2013 |
[Occurrence and risk assessment of five selected PPCPs in municipal wastewater treatment plant and the receiving water].
Topics: China; Cities; Clofibric Acid; Diclofenac; Environmental Monitoring; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2013 |
Non-steroidal anti-inflammatory drugs in Indian rivers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; India; Ketoprofen; Naproxen; Rivers; Sewage; Solid Phase Extraction; Water Pollutants, Chemical | 2014 |
[Problematic: analgesics before the marathon].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Drug Utilization; Female; Humans; Ibuprofen; Male; Pain Management; Premedication; Running | 2013 |
Electrolyte system strategies for anionic isotachophoresis with electrospray-ionization mass-spectrometric detection. 1. Regular isotachophoresis and free-acid isotachophoresis.
Topics: Acids; Analgesics, Non-Narcotic; Anions; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drinking Water; Electrolytes; Electrophoresis, Capillary; Ibuprofen; Isotachophoresis; Limit of Detection; Rivers; Spectrometry, Mass, Electrospray Ionization | 2013 |
Is Atyaephyra desmarestii a useful candidate for lethal and sub-lethal toxicity tests on pharmaceutical compounds?
Topics: Animals; Carbamazepine; Decapoda; Diclofenac; Eating; Ibuprofen; Lethal Dose 50; Osmoregulation; Oxygen; Risk Assessment; Toxicity Tests, Acute; Water Pollutants, Chemical | 2013 |
More pain for painkillers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Naproxen; Pain; Pyrazoles; Risk Factors; Safety-Based Drug Withdrawals; Sulfonamides; United States; United States Food and Drug Administration | 2013 |
Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Ibuprofen; Naproxen; Piroxicam; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 2014 |
Adsorption of selected endocrine disrupting compounds and pharmaceuticals on activated biochars.
Topics: Adsorption; Atrazine; Benzhydryl Compounds; Carbamazepine; Carbon; Charcoal; Chemistry, Pharmaceutical; Diclofenac; Endocrine Disruptors; Environmental Restoration and Remediation; Ethinyl Estradiol; Gases; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Magnetic Resonance Spectroscopy; Oxygen; Phenols; Sulfamethoxazole; Surface Properties; Water; Water Pollutants, Chemical; Water Purification | 2013 |
The impact of nonsteroidal anti-inflammatory drugs on inflammatory response after aneurysmal subarachnoid hemorrhage.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; C-Reactive Protein; Diclofenac; Dipyrone; Female; Glasgow Outcome Scale; Humans; Hypothermia, Induced; Ibuprofen; Inflammation; Interleukin-6; Male; Middle Aged; Practice Patterns, Physicians'; Severity of Illness Index; Subarachnoid Hemorrhage; Treatment Outcome | 2014 |
Effects of aggregation of drug and diagnostic codes on the performance of the high-dimensional propensity score algorithm: an empirical example.
Topics: Adolescent; Adult; Aged; Algorithms; Arthritis; Celecoxib; Confounding Factors, Epidemiologic; Cyclooxygenase 2 Inhibitors; Diclofenac; Gastrointestinal Diseases; Hemorrhage; Humans; Ibuprofen; Incidence; Middle Aged; Models, Statistical; Prevalence; Propensity Score; Pyrazoles; Randomized Controlled Trials as Topic; Risk Factors; Sulfonamides; Treatment Outcome; Young Adult | 2013 |
Biodegradability of pharmaceutical compounds in agricultural soils irrigated with treated wastewater.
Topics: Agricultural Irrigation; Biodegradation, Environmental; Diclofenac; Ibuprofen; Pharmaceutical Preparations; Soil; Soil Microbiology; Soil Pollutants; Sulfamethoxazole; Waste Disposal, Fluid; Wastewater | 2014 |
Microbial removal of the pharmaceutical compounds Ibuprofen and diclofenac from wastewater.
Topics: Bacteria; Biodegradation, Environmental; Bioreactors; Diclofenac; Ibuprofen; Sewage; Wastewater | 2013 |
The impact of diclofenac and ibuprofen on biofilm formation on the surface of polypropylene mesh.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biofilms; Diclofenac; Escherichia coli; Humans; Ibuprofen; Microscopy, Electron, Scanning; Polypropylenes; Staphylococcus aureus; Surgical Mesh | 2015 |
Genotoxic response and oxidative stress induced by diclofenac, ibuprofen and naproxen in Daphnia magna.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Daphnia; Diclofenac; DNA Damage; Ibuprofen; Lipid Peroxidation; Mexico; Mutagenicity Tests; Naproxen; No-Observed-Adverse-Effect Level; Oxidative Stress; Protein Carbonylation; Superoxide Dismutase; Time Factors; Toxicity Tests, Acute; Water Pollutants, Chemical | 2014 |
Binary graft modification of polypropylene for anti-inflammatory drug-device combo products.
Topics: Acrylic Resins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Delayed-Action Preparations; Diclofenac; Gamma Rays; Hydrogen-Ion Concentration; Ibuprofen; Macrophages; Methacrylates; Mice; Nylons; Polypropylenes; Polyvinyls | 2014 |
Cardiovascular safety of NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Ibuprofen; Naproxen | 2014 |
Effects of active pharmaceutical ingredients mixtures in mussel Mytilus galloprovincialis.
Topics: Animals; Biomarkers; Copper; Diclofenac; Enzyme Activation; Fluoxetine; Gene Expression Regulation, Enzymologic; Gills; Ibuprofen; Lipid Peroxidation; Mytilus; Oxidative Stress; Oxidoreductases; Water Pollutants, Chemical | 2014 |
Removal of acidic pharmaceuticals within a nitrifying recirculating biofilter.
Topics: Adsorption; Bacteria; Biofilms; Diclofenac; DNA, Bacterial; Filtration; Gemfibrozil; Genes, Bacterial; Ibuprofen; Naproxen; Nitrification; Waste Disposal, Fluid; Water Pollutants, Chemical | 2014 |
[Simultaneous determination of nine pharmaceuticals personal care products in waters by solid phase extraction-gas chromatography-mass spectrometry].
Topics: Acetaminophen; Agricultural Irrigation; Benzhydryl Compounds; Clofibric Acid; Diclofenac; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Naproxen; Phenols; Salicylic Acid; Solid Phase Extraction; Triclosan; Water; Water Pollutants, Chemical | 2014 |
Numerical modelling of transdermal delivery from matrix systems: parametric study and experimental validation with silicone matrices.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Computer Simulation; Diclofenac; Drug Delivery Systems; Female; Humans; Ibuprofen; Mice, Nude; Models, Biological; Silicones; Skin; Skin Absorption; Solubility | 2014 |
Binary mixtures of diclofenac with paracetamol, ibuprofen, naproxen, and acetylsalicylic acid and these pharmaceuticals in isolated form induce oxidative stress on Hyalella azteca.
Topics: Acetaminophen; Amphipoda; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Catalase; Diclofenac; Glutathione Peroxidase; Ibuprofen; Lipid Peroxidation; Naproxen; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Superoxide Dismutase; Water Pollutants, Chemical | 2014 |
Potent drugs that attenuate anti-Candida albicans activity of fluconazole and their possible mechanisms of action.
Topics: Antifungal Agents; ATP-Binding Cassette Transporters; Candida albicans; Candidiasis; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Fluconazole; Fungal Proteins; Gene Expression; Ibuprofen; Membrane Transport Proteins; Microbial Sensitivity Tests; Omeprazole; Phenylpropionates; Proton Pump Inhibitors | 2014 |
Common analgesics 'pose cardiac risk'.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Heart Diseases; Humans; Ibuprofen; Risk Factors | 2014 |
Effects of anti-inflammatory drugs in primary kidney cell culture of a freshwater fish.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Culture Techniques; Cell Survival; Cells, Cultured; Characidae; Diclofenac; Ibuprofen; Lipopolysaccharides; Mutagenicity Tests; Nitric Oxide | 2014 |
Pollution-induced community tolerance to non-steroidal anti-inflammatory drugs (NSAIDs) in fluvial biofilm communities affected by WWTP effluents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biofilms; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Ecosystem; Ibuprofen; Light; Rivers; Time Factors; Waste Management; Wastewater; Water Pollutants, Chemical; Water Pollution | 2014 |
Biodegradation of ibuprofen, diclofenac and carbamazepine in nitrifying activated sludge under 12 °C temperature conditions.
Topics: Biodegradation, Environmental; Carbamazepine; Cold Temperature; Diclofenac; Finland; Ibuprofen; Nitrification; Sewage; Waste Disposal, Fluid; Water Pollutants, Chemical | 2014 |
Environmental Risk Assessment (ERA) of diclofenac and ibuprofen: a public health perspective.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Brazil; Cities; Diclofenac; Environmental Monitoring; Environmental Pollutants; Forecasting; Humans; Ibuprofen; Public Health; Risk Assessment; Sewage; Waste Disposal, Fluid | 2015 |
Lab-scale experimental strategy for determining micropollutant partition coefficient and biodegradation constants in activated sludge.
Topics: Aerobiosis; Anaerobiosis; Atenolol; Biodegradation, Environmental; Carbon; Denitrification; Diclofenac; Fluoxetine; Ibuprofen; Nitrification; Sewage; Wastewater; Water Pollutants, Chemical | 2015 |
Occurrence of selected pharmaceuticals in the principal sewage treatment plants in Rome (Italy) and in the receiving surface waters.
Topics: Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Estrone; Gemfibrozil; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Rome; Seasons; Solid Phase Extraction; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
Maternal satisfaction with analgesia following hospital discharge after caesarean section.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Codeine; Diclofenac; Female; Heroin; Humans; Ibuprofen; Pain Management; Pain, Postoperative; Patient Discharge; Personal Satisfaction | 2015 |
Ion-exchange selectivity of diclofenac, ibuprofen, ketoprofen, and naproxen in ureolyzed human urine.
Topics: Acetaminophen; Anion Exchange Resins; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Diclofenac; Humans; Hydrogen Bonding; Ibuprofen; Ion Exchange; Ketoprofen; Kinetics; Molecular Structure; Naproxen; Static Electricity; Urea; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
Development of an extraction and purification method for the determination of multi-class pharmaceuticals and endocrine disruptors in freshwater invertebrates.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzhydryl Compounds; Diclofenac; Endocrine Disruptors; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Gastropoda; Ibuprofen; Insecta; Limit of Detection; Phenols; Planarians; Solid Phase Extraction; Sonication; Wastewater; Water Pollutants, Chemical | 2015 |
Evaluation of Prosopis africana Seed Gum as an Extended Release Polymer for Tablet Formulation.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chitosan; Chlorpheniramine; Delayed-Action Preparations; Diclofenac; Drug Carriers; Drug Compounding; Hypromellose Derivatives; Ibuprofen; Plant Gums; Polymers; Polysaccharides, Bacterial; Prosopis; Seeds; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; X-Ray Diffraction | 2015 |
Removing selected steroid hormones, biocides and pharmaceuticals from water by means of biogenic manganese oxide nanoparticles in situ at ppb levels.
Topics: Diclofenac; Disinfectants; Ibuprofen; Manganese Compounds; Nanoparticles; Oxidation-Reduction; Oxides; Pseudomonas putida; Steroids; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Purification | 2015 |
Ionic liquids for improving the extraction of NSAIDs in water samples using dispersive liquid-liquid microextraction by high performance liquid chromatography-diode array-fluorescence detection.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Fluorescence; Ibuprofen; Imidazoles; Ionic Liquids; Ketoprofen; Liquid Phase Microextraction; Water Pollutants, Chemical | 2015 |
Parallel artificial liquid membrane extraction of acidic drugs from human plasma.
Topics: Calibration; Chromatography, High Pressure Liquid; Diclofenac; Equipment Design; Flurbiprofen; Gemfibrozil; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Liquid-Liquid Extraction; Membranes, Artificial; Pharmaceutical Preparations; Polypropylenes; Polyvinyls | 2015 |
Complete Freund's adjuvant-induced reduction of exploratory activity in a novel environment as an objective nociceptive endpoint for sub-acute inflammatory pain model in rats.
Topics: Adjuvants, Immunologic; Amines; Analgesics; Animals; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Duloxetine Hydrochloride; Exploratory Behavior; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Ibuprofen; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley | 2015 |
A novel two-dimensional liquid chromatographic system for the online toxicity prediction of pharmaceuticals and related substances.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Chlorophyta; Chromatography, Liquid; Computer Simulation; Daphnia; Diclofenac; Drug Contamination; Drug-Related Side Effects and Adverse Reactions; Fishes; Ibuprofen; Ketoprofen; Lethal Dose 50; Models, Biological; Pharmaceutical Preparations; Photolysis | 2015 |
NSAIDs and spontaneous abortions - true effect or an indication bias?
Topics: Abortion, Spontaneous; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Israel; Middle Aged; Naproxen; Pregnancy; Retrospective Studies; Time Factors; Young Adult | 2015 |
Adsorption of three pharmaceuticals on two magnetic ion-exchange resins.
Topics: Adsorption; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Hydrogen-Ion Concentration; Ibuprofen; Ion Exchange Resins; Magnetic Phenomena; Sulfadiazine; Water Pollutants, Chemical | 2015 |
AMP-activated protein kinase is activated by non-steroidal anti-inflammatory drugs.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Diclofenac; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Ibuprofen; Mice; Neurons; Protein Subunits | 2015 |
Potential of pulsed corona discharges generated in water for the degradation of persistent pharmaceutical residues.
Topics: Carbamazepine; Diatrizoate; Diazepam; Diclofenac; Environmental Monitoring; Ethinyl Estradiol; Ibuprofen; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2015 |
NSAIDs Ibuprofen, Indometacin, and Diclofenac do not interact with Farnesoid X Receptor.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Diclofenac; Gene Expression; Gene Expression Regulation; Genes, Reporter; Humans; Ibuprofen; Indomethacin; Ligands; Protein Binding; Protein Interaction Domains and Motifs; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Reproducibility of Results; Time Factors | 2015 |
Prevalence, trends, patterns and associations of analgesic use in Germany.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Analgesics; Aspirin; Diclofenac; Drug Therapy; Female; Germany; Health Surveys; Humans; Ibuprofen; Logistic Models; Male; Middle Aged; Multivariate Analysis; Naproxen; Nonprescription Drugs; Pain; Prevalence; Sex Factors; Social Class; Young Adult | 2015 |
Ibuprofen and Diclofenac Restrict Migration and Proliferation of Human Glioma Cells by Distinct Molecular Mechanisms.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Cell Cycle Checkpoints; Cell Division; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diclofenac; Glioma; Humans; Ibuprofen | 2015 |
Single-drop microextraction combined in-line with capillary electrophoresis for the determination of nonsteroidal anti-inflammatory drugs in urine samples.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrophoresis, Capillary; Equipment Design; Humans; Ibuprofen; Ketoprofen; Limit of Detection; Liquid Phase Microextraction; Naproxen; Urinalysis | 2016 |
Occurrence of non-steroidal anti-inflammatory drugs in Tehran source water, municipal and hospital wastewaters, and their ecotoxicological risk assessment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Liquid; Diclofenac; Ecotoxicology; Environmental Monitoring; Hospitals; Ibuprofen; Iran; Mass Spectrometry; Naproxen; Risk Assessment; Rivers; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2015 |
Cysteine amide adduct formation from carboxylic acid drugs via UGT-mediated bioactivation in human liver microsomes.
Topics: Amides; Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Acids; Chromatography, High Pressure Liquid; Cysteine; Diclofenac; Glucuronosyltransferase; Humans; Ibuprofen; In Vitro Techniques; Ketoprofen; Microsomes, Liver; Spectrometry, Mass, Electrospray Ionization | 2015 |
Graphene oxide-based dispersive solid-phase extraction combined with in situ derivatization and gas chromatography-mass spectrometry for the determination of acidic pharmaceuticals in water.
Topics: Diclofenac; Gas Chromatography-Mass Spectrometry; Graphite; Ibuprofen; Ketoprofen; Naproxen; Osmolar Concentration; Pharmaceutical Preparations; Solid Phase Extraction; Solvents; Water; Water Pollutants, Chemical | 2015 |
Subtle structural changes in the Asp251Gly/Gln307His P450 BM3 mutant responsible for new activity toward diclofenac, tolbutamide and ibuprofen.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Computer Simulation; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Activation; Ibuprofen; Molecular Docking Simulation; Molecular Sequence Data; Mutation; NADPH-Ferrihemoprotein Reductase; Protein Binding; Protein Conformation; Structure-Activity Relationship; Tolbutamide | 2016 |
The Influence of Efflux Pump Inhibitors on the Activity of Non-Antibiotic NSAIDS against Gram-Negative Rods.
Topics: Acetaminophen; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Escherichia coli; Gram-Negative Bacteria; Ibuprofen; Mefenamic Acid; Microbial Sensitivity Tests; Naproxen | 2016 |
Capillary isotachophoresis with ESI-MS detection: Methodology for highly sensitive analysis of ibuprofen and diclofenac in waters.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Isotachophoresis; Limit of Detection; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Water Pollutants, Chemical | 2016 |
Adsorption behavior and mechanism of chloramphenicols, sulfonamides, and non-antibiotic pharmaceuticals on multi-walled carbon nanotubes.
Topics: Adsorption; Anti-Bacterial Agents; Carbamazepine; Chloramphenicol; Diclofenac; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Nanotubes, Carbon; Sulfonamides; Waste Disposal, Fluid; Water Pollutants, Chemical | 2016 |
NSAIDs and serious cardiovascular disorders: especially cox-2 inhibitors and diclofenac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Ibuprofen; Naproxen | 2016 |
Acute interstitial nephritis due to flecainide therapy in the 38(th) week of pregnancy.
Topics: Acute Disease; Acute Kidney Injury; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Diclofenac; Female; Fetal Diseases; Flecainide; Humans; Ibuprofen; Nephritis, Interstitial; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Young Adult | 2016 |
Non-steroidal Anti-inflammatory Drugs Attenuate Hyperalgesia and Block Upregulation of Trigeminal Ganglionic Sodium Channel 1.7 after Induction of Temporomandibular Joint Inflammation in Rats.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Diclofenac; Eating; Female; Freund's Adjuvant; Hyperalgesia; Ibuprofen; Meloxicam; NAV1.7 Voltage-Gated Sodium Channel; Nociception; Pain Threshold; Rats; Rats, Sprague-Dawley; Synovial Membrane; Temporomandibular Joint; Temporomandibular Joint Disorders; Thiazines; Thiazoles; Trigeminal Ganglion; Up-Regulation | 2016 |
Use of non-steroidal anti-inflammatory drugs correlates with the risk of venous thromboembolism in knee osteoarthritis patients: a UK population-based case-control study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Lactones; Logistic Models; Male; Meloxicam; Middle Aged; Naproxen; Odds Ratio; Osteoarthritis, Knee; Risk Factors; Sulfones; Thiazines; Thiazoles; Treatment Outcome; United Kingdom; Venous Thromboembolism | 2016 |
Low-dose Aspirin, Nonsteroidal Anti-inflammatory Drugs, Selective COX-2 Inhibitors and Breast Cancer Recurrence.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Breast Neoplasms; Cyclooxygenase 2 Inhibitors; Denmark; Diclofenac; Female; Follow-Up Studies; Humans; Ibuprofen; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Proportional Hazards Models; Protective Factors; Registries | 2016 |
Common pain relievers may increase heart problems. High-dosage ibuprofen and diclofenac linked to elevated risk of death; naproxen, acetaminophen offer alternatives.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Naproxen; Pain | 2010 |
Ecotoxicological potential of non-steroidal anti-inflammatory drugs (NSAIDs) in marine organisms: Bioavailability, biomarkers and natural occurrence in Mytilus galloprovincialis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aquatic Organisms; Biomarkers; Diclofenac; Ecotoxicology; Environmental Monitoring; Ibuprofen; Mytilus; Oxidative Stress; Water Pollutants, Chemical | 2016 |
Influence of temperature on toxicity of single pharmaceuticals and mixtures, in the crustacean A. desmarestii.
Topics: Animals; Carbamazepine; Decapoda; Diclofenac; Ibuprofen; Temperature; Water Pollutants, Chemical | 2016 |
Toxicity Thresholds for Diclofenac, Acetaminophen and Ibuprofen in the Water Flea Daphnia magna.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Daphnia; Diclofenac; Ibuprofen; Reproduction; Water Pollutants, Chemical | 2016 |
Comparative study of emerging micropollutants removal by aerobic activated sludge of large laboratory-scale membrane bioreactors and sequencing batch reactors under low-temperature conditions.
Topics: Aerobiosis; Biodegradation, Environmental; Bioreactors; Chromatography, Liquid; Cold Temperature; Diclofenac; Estrone; Ibuprofen; Sewage; Tandem Mass Spectrometry; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2016 |
Evaluation of acute effects of four pharmaceuticals and their mixtures on the copepod Tisbe battagliai.
Topics: Acetaminophen; Animals; Carbamazepine; Copepoda; Diclofenac; Ibuprofen; Pharmaceutical Preparations; Toxicity Tests, Acute; Water Pollutants, Chemical | 2016 |
Guar gum succinate-sodium alginate beads as a pH-sensitive carrier for colon-specific drug delivery.
Topics: Alginates; Animals; Cell Line; Colon; Diclofenac; Drug Carriers; Drug Liberation; Galactans; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Ibuprofen; Mannans; Mice; Microspheres; Organ Specificity; Plant Gums; Succinates | 2016 |
Suitability of passive sampling for the monitoring of pharmaceuticals in Finnish surface waters.
Topics: Calibration; Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Finland; Ibuprofen; Ketoprofen; Lakes; Naproxen; Pharmaceutical Preparations; Rivers; Seasons; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2016 |
Determination of ibuprofen, naproxen and diclofenac in aqueous samples using a multi-template molecularly imprinted polymer as selective adsorbent for solid-phase extraction.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Drug Residues; Ibuprofen; Indicators and Reagents; Molecular Imprinting; Naproxen; Pharmaceutical Solutions; Polymers; Reproducibility of Results; Rivers; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2016 |
Biophysical study of the non-steroidal anti-inflammatory drugs (NSAID) ibuprofen, naproxen and diclofenac with phosphatidylserine bilayer membranes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Lipid Bilayers; Naproxen; Phosphatidylserines | 2016 |
Sunitinib DDI with paracetamol, diclofenac, mefenamic acid and ibuprofen shows sex-divergent effects on the tissue uptake and distribution pattern of sunitinib in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Diclofenac; Drug Interactions; Female; Ibuprofen; Indoles; Male; Mefenamic Acid; Mice; Mice, Inbred ICR; Pyrroles; Sex Characteristics; Sunitinib; Tissue Distribution | 2016 |
(1)H-Nuclear magnetic resonance-based metabolic profiling of nonsteroidal anti-inflammatory drug-induced adverse effects in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug-Related Side Effects and Adverse Reactions; Gastric Mucosa; Ibuprofen; Indomethacin; Least-Squares Analysis; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolomics; Piroxicam; Rats; Rats, Sprague-Dawley | 2016 |
The fate of selected pharmaceuticals in solar stills: Transfer, thermal degradation or photolysis?
Topics: Ampicillin; Carbamazepine; Diclofenac; Drug Residues; Ibuprofen; Naproxen; Photolysis; Sunlight; Water Pollutants, Chemical | 2017 |
Fabrication of non-dissolving analgesic suppositories using 3D printed moulds.
Topics: Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Drug Liberation; Elastic Modulus; Ibuprofen; Ketoprofen; Lidocaine; Mice; Printing, Three-Dimensional; Silicone Elastomers; Solubility; Suppositories; Tensile Strength | 2016 |
Central nervous system toxicity of mefenamic acid overdose compared with other NSAIDs: an analysis of cases reported to the United Kingdom National Poisons Information Service.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Diclofenac; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Ibuprofen; Infant; Infant, Newborn; Logistic Models; Male; Mefenamic Acid; Middle Aged; Multivariate Analysis; Naproxen; Neurotoxicity Syndromes; Poison Control Centers; Sex Factors; United Kingdom; Young Adult | 2017 |
Ecological risk assessment of pharmaceuticals in the receiving environment of pharmaceutical wastewater in Pakistan.
Topics: Animals; Diclofenac; Ecology; Environmental Monitoring; Fishes; Fluoroquinolones; Gemifloxacin; Ibuprofen; Moxifloxacin; Naphthyridines; Pakistan; Risk Assessment; Sewage; Wastewater; Water Pollutants, Chemical | 2017 |
Poly(aryleneethynylene) Tongue That Identifies Nonsteroidal Anti-Inflammatory Drugs in Water: A Test Case for Combating Counterfeit Drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Counterfeit Drugs; Diclofenac; Ibuprofen; Naproxen; Water | 2017 |
Non-steroidal anti-inflammatory drugs in the watercourses of Elbe basin in Czech Republic.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Czech Republic; Diclofenac; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Rivers; Water Pollutants, Chemical | 2017 |
Non-steroidal anti-inflammatory drug use is associated with increased risk of out-of-hospital cardiac arrest: a nationwide case-time-control study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Denmark; Diclofenac; Drug Utilization; Humans; Ibuprofen; Incidence; Middle Aged; Odds Ratio; Out-of-Hospital Cardiac Arrest; Registries; Risk Assessment; Risk Factors; Survival Rate | 2017 |
Cyto-genotoxicity and oxidative stress in common carp (Cyprinus carpio) exposed to a mixture of ibuprofen and diclofenac.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carps; Comet Assay; Diclofenac; DNA Damage; Drug Combinations; Gills; Ibuprofen; Lipid Peroxidation; Oxidative Stress; Water Pollutants, Chemical | 2017 |
Mass spectrometry based in vitro assay investigations on the transformation of pharmaceutical compounds by oxidative enzymes.
Topics: Acetaminophen; Carbamazepine; Diclofenac; Horseradish Peroxidase; Ibuprofen; Laccase; Mass Spectrometry; Naproxen; Oxidation-Reduction; Sotalol; Sulfamethoxazole; Water Pollutants, Chemical; Water Purification | 2017 |
Sorption and desorption of selected non-steroidal anti-inflammatory drugs in an agricultural loam-textured soil.
Topics: Adsorption; Agriculture; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Ketoprofen; Naproxen; Soil; Soil Pollutants | 2017 |
Assessing the impact of diclofenac, ibuprofen and sildenafil citrate (Viagra
Topics: Animals; Aquatic Organisms; Diclofenac; Echinodermata; Environmental Monitoring; Ibuprofen; Invertebrates; Polychaeta; Reproduction; Sildenafil Citrate; Water Pollutants, Chemical | 2017 |
Effects of ibuprofen, diclofenac and paracetamol on hatch and motor behavior in developing zebrafish (Danio rerio).
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Embryo, Nonmammalian; Ibuprofen; Locomotion; Reproduction; Zebrafish | 2017 |
Ibuprofen and diclofenac treatments reduce proliferation of pancreatic acinar cells upon inflammatory injury and mitogenic stimulation.
Topics: Acinar Cells; Animals; Cell Differentiation; Cell Proliferation; Ceruletide; Cytokines; Diclofenac; Ibuprofen; Inflammation; Male; Mice; Mitogens; Neutrophil Infiltration; Pancreas; Pancreatitis; Triiodothyronine | 2018 |
Nonsteroidal anti-inflammatory drugs-induced failure of lower esophageal and pyloric sphincter and counteraction of sphincters failure with stable gatric pentadecapeptide BPC 157 in rats.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Celecoxib; Diclofenac; Esophageal Sphincter, Lower; Ibuprofen; Male; Peptide Fragments; Pressure; Proteins; Pylorus; Rats, Wistar | 2017 |
Occurrence of naproxen, ibuprofen, and diclofenac residues in wastewater and river water of KwaZulu-Natal Province in South Africa.
Topics: Chromatography, High Pressure Liquid; Cities; Diclofenac; Dose-Response Relationship, Drug; Environmental Monitoring; Ibuprofen; Naproxen; Rivers; Solid Phase Extraction; South Africa; Wastewater; Water Pollutants, Chemical | 2017 |
Bacterial diversity and population shifts driven by spotlight wastewater micropollutants in low-temperature highly nitrifying activated sludge.
Topics: Bacteria; Bioreactors; Diclofenac; Estrone; Ethinyl Estradiol; Ibuprofen; Nitrification; Sewage; Temperature; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2017 |
Synergistic effect of non-steroidal anti-inflammatory drugs (NSAIDs) on antibacterial activity of cefuroxime and chloramphenicol against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cefuroxime; Chloramphenicol; Diclofenac; Drug Combinations; Drug Interactions; Drug Resistance, Multiple, Bacterial; Drug Synergism; Ibuprofen; Mefenamic Acid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcus aureus | 2017 |
Nonsteroidal Anti-inflammatory Drugs (NSAIDS) Inhibit the Growth and Reproduction of Chaetomium globosum and Other Fungi Associated with Water-Damaged Buildings.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Aspergillus; Aspirin; Cell Proliferation; Chaetomium; Diclofenac; Diflunisal; Fusarium; Germination; Humans; Ibuprofen; Lung Diseases, Fungal; Microbial Sensitivity Tests; Mycoses; Stachybotrys | 2017 |
NSAIDs relieve osteoarthritis (OA) pain, but cardiovascular safety in question even for diclofenac, ibuprofen, naproxen, and celecoxib: what are the alternatives?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Diclofenac; Humans; Ibuprofen; Naproxen; Network Meta-Analysis; Osteoarthritis; Pain | 2017 |
Efficacy and safety of diclofenac in osteoarthritis: Results of a network meta-analysis of unpublished legacy studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Network Meta-Analysis; Osteoarthritis; Pain Measurement; Randomized Controlled Trials as Topic | 2017 |
Degradation and intermediates of diclofenac as instructive example for decomposition of recalcitrant pharmaceuticals by hydroxyl radicals generated with pulsed corona plasma in water.
Topics: Carbamazepine; Diclofenac; Electron Spin Resonance Spectroscopy; Ethinyl Estradiol; Hydrogen Peroxide; Hydroxyl Radical; Ibuprofen; Water | 2018 |
Determination of acidic non-steroidal anti-inflammatory drugs in aquatic samples by liquid chromatography-triple quadrupole mass spectrometry combined with carbon nanotubes-based solid-phase extraction.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Ibuprofen; Latvia; Limit of Detection; Nanotubes, Carbon; Norway; Solid Phase Extraction; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical | 2017 |
Penetration and pharmacokinetics of non-steroidal anti-inflammatory drugs in rat prostate tissue.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Celecoxib; Chromatography, Liquid; Comparative Effectiveness Research; Diclofenac; Disease Models, Animal; Ibuprofen; Inflammation; Male; Naproxen; Pelvic Pain; Prostate; Prostatitis; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2018 |
Coupling of two centrifugeless ultrasound-assisted dispersive solid/liquid phase microextractions as a highly selective, clean, and efficient method for determination of ultra-trace amounts of non-steroidal anti-inflammatory drugs in complicated matrices.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Hydrogen-Ion Concentration; Hydroxides; Ibuprofen; Limit of Detection; Liquid Phase Microextraction; Mefenamic Acid; Nanotubes, Carbon; Solid Phase Microextraction; Solvents; Ultrasonic Waves; Wastewater | 2018 |
Development of an in-line Raman spectroscopic method for continuous API quantification during twin-screw wet granulation.
Topics: Chemistry, Pharmaceutical; Diclofenac; Ibuprofen; Spectrum Analysis, Raman | 2018 |
Long-term exposure of Mytilus galloprovincialis to diclofenac, Ibuprofen and Ketoprofen: Insights into bioavailability, biomarkers and transcriptomic changes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Biomarkers; Diclofenac; Ecotoxicology; Ibuprofen; Ketoprofen; Mytilus; Transcriptome; Water Pollutants, Chemical | 2018 |
A model assessment of the potential of river water to induce the photochemical attenuation of pharmaceuticals downstream of a wastewater treatment plant (Guadiana River, Badajoz, Spain).
Topics: Biodegradation, Environmental; Carbamazepine; Diclofenac; Fresh Water; Ibuprofen; Kinetics; Photolysis; Rivers; Spain; Sunlight; Wastewater; Water Pollutants, Chemical; Water Purification | 2018 |
Degradation of anti-inflammatory drugs in municipal wastewater by heterogeneous photocatalysis and electro-Fenton process.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Hydrogen Peroxide; Ibuprofen; Naproxen; Wastewater; Water Pollutants, Chemical | 2019 |
Comparative cardiovascular safety of nonsteroidal anti-inflammatory drugs in patients with hypertension: a population-based cohort study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular System; Celecoxib; Cyclooxygenase 2 Inhibitors; Databases, Pharmaceutical; Diclofenac; Female; Hospitalization; Humans; Hypertension; Ibuprofen; Male; Mefenamic Acid; Middle Aged; Naproxen; Risk Factors | 2018 |
Micropollutant removal from black water and grey water sludge in a UASB-GAC reactor.
Topics: Anaerobiosis; Benzopyrans; Bioreactors; Carbon; Diclofenac; Ibuprofen; Metoprolol; Sewage; Triclosan; Waste Disposal, Fluid; Water Pollutants, Chemical | 2018 |
Effect on Risk of Stroke and Acute Myocardial Infarction of Nonselective Nonsteroidal Anti-Inflammatory Drugs in Patients With Rheumatoid Arthritis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Diclofenac; Female; Humans; Ibuprofen; Logistic Models; Male; Mefenamic Acid; Meloxicam; Middle Aged; Myocardial Infarction; Odds Ratio; Risk Factors; Stroke | 2018 |
Prevalence of selected pharmaceuticals in surface water receiving untreated sewage in northwest Pakistan.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aquatic Organisms; Chromatography, Liquid; Cities; Diclofenac; Environmental Monitoring; Ibuprofen; Pakistan; Pharmaceutical Preparations; Prevalence; Risk Assessment; Rivers; Sewage; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical; Water Pollution, Chemical | 2018 |
Transformation, CO
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Biofilms; Carbon Dioxide; Deltaproteobacteria; Diclofenac; Firmicutes; Gammaproteobacteria; Ibuprofen; In Situ Hybridization, Fluorescence; Naproxen; RNA, Ribosomal, 16S; Waste Disposal, Fluid; Wastewater; Water Microbiology; Water Pollutants, Chemical | 2018 |
[Removal Behavior of Ibuprofen and Diclofenac in Different Constructed Wetlands].
Topics: Biodegradation, Environmental; Diclofenac; Ibuprofen; Photolysis; Seasons; Water Pollutants, Chemical; Wetlands | 2016 |
Analgesic prescribing patterns of dental practitioners in Germany.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Prescriptions; Germany; Humans; Ibuprofen; Practice Patterns, Dentists'; Practice Patterns, Physicians'; Sulfonamides | 2018 |
Spatial distribution of pharmaceuticals in conventional wastewater treatment plant with Sludge Treatment Reed Beds technology.
Topics: Diclofenac; Ibuprofen; Pharmaceutical Preparations; Sewage; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2019 |
Diclofenac use and cardiovascular risks: series of nationwide cohort studies.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cohort Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Propensity Score; Risk Factors | 2018 |
Comparative study of the toxicity between three non-steroidal anti-inflammatory drugs and their UV/Na
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carps; Diclofenac; Ecological Parameter Monitoring; Environmental Pollutants; Environmental Pollution; Fish Diseases; Ibuprofen; Medical Waste Disposal; Naproxen; Oxidation-Reduction; Photolysis; Sodium Compounds; Sulfates; Toxicity Tests, Acute; Ultraviolet Rays; Wastewater; Water Purification | 2018 |
A fugacity model assessment of ibuprofen, diclofenac, carbamazepine, and their transformation product concentrations in an aquatic environment.
Topics: Carbamazepine; Diclofenac; Environmental Monitoring; Finland; Ibuprofen; Lakes; Models, Chemical; Photolysis; Wastewater; Water Pollutants, Chemical | 2019 |
C18-Coated Solid-Phase Microextraction Fibers for the Quantification of Partitioning of Organic Acids to Proteins, Lipids, and Cells.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Cattle; Cells, Cultured; Diclofenac; Genistein; HEK293 Cells; Humans; Ibuprofen; Kinetics; Liposomes; Naproxen; Phospholipids; Serum Albumin, Bovine; Solid Phase Microextraction; Torsemide; Warfarin | 2019 |
Assessing the effect of human pharmaceuticals (carbamazepine, diclofenac and ibuprofen) on the marine clam Ruditapes philippinarum: An integrative and multibiomarker approach.
Topics: Acetylcholinesterase; Animals; Biomarkers; Bivalvia; Carbamazepine; Diclofenac; Gills; Humans; Ibuprofen; Lipid Peroxidation; Metallothionein; Oxidative Stress; Water Pollutants, Chemical | 2019 |
[Prescribing of Non-Steroidal Anti-Inflammatory Drugs to Patients with Diabetes Mellitus in Portugal].
Topics: Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Diabetes Mellitus; Diclofenac; Dipyrone; Female; Humans; Ibuprofen; Male; Middle Aged; Portugal; Renal Insufficiency, Chronic; Retrospective Studies; Specialization; Young Adult | 2019 |
Nickel-iron layered double hydroxide nanostructures for micro solid phase extraction of nonsteroidal anti-inflammatory drugs, followed by quantitation by HPLC-UV.
Topics: Adsorption; Alloys; Anti-Inflammatory Agents, Non-Steroidal; Biosensing Techniques; Chromatography, High Pressure Liquid; Diclofenac; Humans; Hydroxides; Ibuprofen; Iron; Limit of Detection; Mefenamic Acid; Metal Nanoparticles; Naproxen; Nickel; Reproducibility of Results; Solid Phase Microextraction; Surface Properties | 2019 |
Application and performance evaluation of a cost-effective vis- LED based fluidized bed reactor for the treatment of emerging contaminants.
Topics: Carbamazepine; Catalysis; Cost-Benefit Analysis; Diclofenac; Equipment Design; Ibuprofen; Light; Pharmaceutical Preparations; Photochemical Processes; Water Pollutants, Chemical; Water Purification | 2019 |
Microcavity-Supported Lipid Bilayers; Evaluation of Drug-Lipid Membrane Interactions by Electrochemical Impedance and Fluorescence Correlation Spectroscopy.
Topics: Alendronate; Clodronic Acid; Diclofenac; Dielectric Spectroscopy; Electric Impedance; Ibuprofen; Levofloxacin; Lipid Bilayers; Pefloxacin; Rifampin; Spectrometry, Fluorescence | 2019 |
Evaluation of the photosynthetic parameters, emission of volatile organic compounds and ultrastructure of common green leafy vegetables after exposure to non-steroidal anti-inflammatory drugs (NSAIDs).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Atriplex; Diclofenac; Environmental Pollutants; Ibuprofen; Lactuca; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Naproxen; Photosynthesis; Plant Leaves; Spinacia oleracea; Volatile Organic Compounds | 2019 |
Oxyfunctionalization of nonsteroidal anti-inflammatory drugs by filamentous-fungi.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Basidiomycota; Cytochrome P-450 Enzyme System; Diclofenac; Fungi; Ibuprofen; Mefenamic Acid; Mucor; Naproxen; Proteomics | 2019 |
Amine modified magnetic polystyrene for extraction of drugs from urine samples.
Topics: Amines; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Limit of Detection; Magnetics; Pharmaceutical Preparations; Polystyrenes; Reproducibility of Results; Solid Phase Extraction; Spectroscopy, Fourier Transform Infrared; Wastewater | 2019 |
Bioremoval of non-steroidal anti-inflammatory drugs by Pseudoxanthomonas sp. DIN-3 isolated from biological activated carbon process.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Charcoal; Diclofenac; Ecosystem; Ibuprofen; Naproxen | 2019 |
A nanohybrid composed of polyoxotungstate and graphene oxide for dispersive micro solid-phase extraction of non-steroidal anti-inflammatory drugs prior to their quantitation by HPLC.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Graphite; Ibuprofen; Limit of Detection; Nanostructures; Naproxen; Polymers; Porosity; Solid Phase Extraction; Spectrophotometry, Ultraviolet; Tungsten Compounds; Water Pollutants, Chemical | 2019 |
Relative Expression of Mouse Udp-glucuronosyl Transferase 2b1 Gene in the Livers, Kidneys, and Hearts: The Influence of Nonsteroidal Anti-inflammatory Drug Treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Glucuronosyltransferase; Ibuprofen; Kidney; Liver; Male; Mefenamic Acid; Meloxicam; Mice, Inbred BALB C; Myocardium | 2019 |
Monitoring the release of anti-inflammatory and analgesic pharmaceuticals in the receiving environment.
Topics: Analgesics; Anti-Inflammatory Agents; Diclofenac; Environmental Monitoring; Hospitals; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Seasons; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2019 |
Ibuprofen and diclofenac impair the cardiovascular development of zebrafish (Danio rerio) at low concentrations.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Embryo, Nonmammalian; Ibuprofen; Organogenesis; Water Pollutants, Chemical; Zebrafish | 2020 |
Optimization of the Interaction between Diclofenac and Ibuprofen with Benzalkonium Chloride to Prepare Ocular Nanosuspension.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzalkonium Compounds; Cornea; Diclofenac; Drug Compounding; Drug Stability; Excipients; Goats; Ibuprofen; Nanoparticles; Particle Size; Preservatives, Pharmaceutical; Solubility; Suspensions | 2019 |
Topical Drug Delivery Systems Based on Bacterial Nanocellulose: Accelerated Stability Testing.
Topics: Administration, Topical; Bacteria; Biocompatible Materials; Caffeine; Cellulose; Diclofenac; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Stability; Humans; Ibuprofen; Lidocaine; Nanoparticles | 2020 |
Synthesis, chemical characterization and DNA interaction study of new diclofenac and ibuprofen zinc (II)-nicotinamide ternary complexes as cyclooxygenase inhibitor prototypes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Artemia; Coordination Complexes; Crystallography, X-Ray; Cyclooxygenase Inhibitors; Diclofenac; DNA Cleavage; Ibuprofen; Molecular Structure; Niacinamide; Toxicity Tests, Acute; Zinc | 2020 |
In-situ synthesis of flower like Co
Topics: Acetaminophen; Acids; Adsorption; Adult; Aluminum; Aspirin; Chromatography, High Pressure Liquid; Cobalt; Diclofenac; Electrochemical Techniques; Electrodes; Female; Humans; Hydroxides; Ibuprofen; Limit of Detection; Male; Nanotubes; Oxides; Reproducibility of Results; Solid Phase Microextraction; Surface Properties | 2020 |
A tunable extruded 3D printing platform using thermo-sensitive pastes.
Topics: Cellulose; Delayed-Action Preparations; Diclofenac; Excipients; Gelatin; Glycerol; Hydrodynamics; Hypromellose Derivatives; Ibuprofen; Lactose; Mannitol; Printing, Three-Dimensional; Rheology; Technology, Pharmaceutical; Viscosity; Water | 2020 |
Anti-inflammatory Cotton Fabrics and Silica Nanoparticles with Potential Topical Medical Applications.
Topics: Amides; Animals; Anti-Inflammatory Agents; Cotton Fiber; Diclofenac; Drug Liberation; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Leukocytes; Nanoparticles; Peptide Hydrolases; Rats; Salicylic Acid; Silicon Dioxide | 2020 |
Rapid exposure of macrophages to drugs resolves four classes of effects on the leading edge sensory pseudopod: Non-perturbing, adaptive, disruptive, and activating.
Topics: Acetaminophen; Adaptation, Physiological; Animals; Aspirin; Cell Movement; Cell Polarity; Diclofenac; Humans; Ibuprofen; Immunity, Innate; Macrophages; Mice; Pseudopodia; RAW 264.7 Cells; Time-Lapse Imaging | 2020 |
Diet quality and NSAIDs promote changes in formation of prostaglandins by an aquatic invertebrate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Diclofenac; Diet; Ibuprofen; Invertebrates; Ketoprofen; Lipid Metabolism; Naproxen; Prostaglandins | 2020 |
Prescriber responsibility, predictors for initiation, and 20-year trends in use of non-aspirin non-steroidal anti-inflammatory drugs in patients with cardiovascular contraindications: a nationwide cohort study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Ibuprofen | 2021 |
Methanogenic potential of diclofenac and ibuprofen in sanitary sewage using metabolic cosubstrates.
Topics: Anaerobiosis; Diclofenac; Ibuprofen; Methane; RNA, Ribosomal, 16S; Sewage; Wastewater | 2020 |
Profiling of drug crystallization in the skin.
Topics: Administration, Cutaneous; Animals; Crystallization; Diclofenac; Humans; Ibuprofen; Scattering, Small Angle; Skin; Skin Absorption; Spectrum Analysis, Raman; Swine; X-Ray Diffraction | 2020 |
Ciprofloxacin, diclofenac, ibuprofen and 17α-ethinylestradiol differentially affect the activity of acetogens and methanogens in anaerobic communities.
Topics: Anaerobiosis; Bacteria; Ciprofloxacin; Diclofenac; Ethinyl Estradiol; Ibuprofen; Microbiota; Wastewater; Water Pollutants, Chemical | 2020 |
A banana peel/silicon glue coated stir bar for extraction of aspirin, diclofenac, ibuprofen and mefenamic acid followed by high performance liquid chromatography-UV detection.
Topics: Aspirin; Chromatography, High Pressure Liquid; Diclofenac; Humans; Ibuprofen; Mefenamic Acid; Musa; Reproducibility of Results; Silicon; Spectrophotometry, Ultraviolet | 2020 |
Bacterial ecotoxicity and shifts in bacterial communities associated with the removal of ibuprofen, diclofenac and triclosan in biopurification systems.
Topics: Cosmetics; Diclofenac; Ibuprofen; Pharmaceutical Preparations; Triclosan; Water Pollutants, Chemical | 2020 |
Applicability of capillary electrophoresis-frontal analysis for displacement studies: Effect of several drugs on l-tryptophan and lidocaine binding to human serum albumin.
Topics: Binding Sites; Chlorpropamide; Diclofenac; Electrophoresis, Capillary; Flurbiprofen; Humans; Ibuprofen; Lidocaine; Phenylbutazone; Serum Albumin, Human; Tolbutamide; Tryptophan | 2020 |
Comparative evaluation of topical diclofenac sodium versus topical ibuprofen in the treatment of seborrheic keratosis.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gels; Humans; Ibuprofen; Keratosis, Seborrheic; Treatment Outcome | 2020 |
Synthesis and application of magnetic@layered double hydroxide as an anti-inflammatory drugs nanocarrier.
Topics: Animals; Anti-Inflammatory Agents; Delayed-Action Preparations; Diclofenac; Drug Carriers; Drug Compounding; Drug Liberation; Humans; Hydroxides; Ibuprofen; Intercalating Agents; Magnetic Iron Oxide Nanoparticles; Mice; Myoblasts; Nanocomposites; Particle Size; Solubility; Surface Properties | 2020 |
Employ of arbuscular mycorrhizal fungi for pharmaceuticals ibuprofen and diclofenac removal in mesocosm-scale constructed wetlands.
Topics: Diclofenac; Fungi; Ibuprofen; Mycorrhizae; Pharmaceutical Preparations; Plant Roots; Wetlands | 2021 |
Diclofenac and Ibuprofen Determination in Sewage Sludge Using a QuEChERS Approach: Occurrence and Ecological Risk Assessment in Three Nigerian Wastewater Treatment Plants.
Topics: Animals; Diclofenac; Ibuprofen; Nigeria; Reproducibility of Results; Risk Assessment; Sewage; Solid Phase Extraction; Water Purification | 2021 |
In-situ synthesis of nanocubic cobalt oxide @ graphene oxide nanocomposite reinforced hollow fiber-solid phase microextraction for enrichment of non-steroidal anti-inflammatory drugs from human urine prior to their quantification via high-performance liqu
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Cobalt; Diclofenac; Female; Graphite; Humans; Ibuprofen; Limit of Detection; Male; Mefenamic Acid; Nanocomposites; Oxides; Solid Phase Microextraction; Ultraviolet Rays | 2021 |
Evaluation of ibuprofen and diclofenac in the main rivers of Colombia and striped catfish Pseudoplatystoma magdaleniatum.
Topics: Animals; Catfishes; Colombia; Diclofenac; Environmental Monitoring; Ibuprofen; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2021 |
Effective treatment of hospital wastewater with high-concentration diclofenac and ibuprofen using a promising technology based on degradation reaction catalyzed by Fe
Topics: Catalysis; Diclofenac; Hospitals; Ibuprofen; Microwaves; Technology; Wastewater; Water Pollutants, Chemical | 2021 |
Quantification of the inflammatory responses to pro-and anti-inflammatory agents in Manila clam, Ruditapes philippinarum.
Topics: Animals; Bivalvia; Calcium-Binding Proteins; Cyclooxygenase 2; Diclofenac; Gene Expression; Ibuprofen; Immunity, Innate; Lipopolysaccharides; Nitric Oxide; Water Pollutants, Chemical | 2021 |
Topical NSAIDs for acute local pain relief:
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Pharmaceutical Preparations; Skin | 2021 |
The Anti-Inflammatory Effect of a γ-Lactone Isolated from Ostrich Oil of
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Diclofenac; Edema; Emulsions; Formaldehyde; Ibuprofen; Lactones; Male; Palaeognathae; Rats; Rats, Wistar; Skin; Struthioniformes | 2021 |
Arbuscular mycorrhizal symbiosis in constructed wetlands with different substrates: Effects on the phytoremediation of ibuprofen and diclofenac.
Topics: Biodegradation, Environmental; Diclofenac; Ibuprofen; Mycorrhizae; Plant Roots; Symbiosis; Wetlands | 2021 |
Layered terbium hydroxides for simultaneous drug delivery and imaging.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Cell Survival; Diclofenac; Drug Delivery Systems; Drug Liberation; Drug Stability; Erythrocytes; Female; HEK293 Cells; Hemolysis; Humans; Hydroxides; Ibuprofen; Ion Exchange; Naproxen; Optical Imaging; Rats, Wistar; Terbium | 2021 |
In-sewer stability of selected analgesics and their metabolites.
Topics: Analgesics; Carboxylic Acids; Diclofenac; Ibuprofen; Ketoprofen | 2021 |
Experimental evidence for proarrhythmic effects of nonsteroidal anti-inflammatory drugs in a sensitive whole-heart model.
Topics: Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Cardiac Electrophysiology; Diclofenac; Dose-Response Relationship, Drug; Electrocardiography; Female; Ibuprofen; Indomethacin; Isolated Heart Preparation; Rabbits; Tachycardia, Ventricular | 2022 |
Design and application of molecularly imprinted polymers for adsorption and environmental assessment of anti-inflammatory drugs in wastewater samples.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Emulsions; Ibuprofen; Molecular Imprinting; Molecularly Imprinted Polymers; Naproxen; Wastewater | 2022 |
A novel and affordable bioaugmentation strategy with microbial extracts to accelerate the biodegradation of emerging contaminants in different media.
Topics: Biodegradation, Environmental; Diclofenac; Ibuprofen; Plant Extracts; Triclosan | 2022 |
Pharmaceuticals and other contaminants of emerging concern in Admiralty Bay as a result of untreated wastewater discharge: Status and possible environmental consequences.
Topics: Caffeine; Cosmetics; Diclofenac; Environmental Monitoring; Humans; Ibuprofen; Ketoconazole; Pharmaceutical Preparations; Wastewater; Water Pollutants, Chemical | 2022 |
The Effects of Ibuprofen, Naproxen and Diclofenac on cell Apoptosis, Cell Proliferation and Histology Changes in Human Cholangiocarcinoma Cell Lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; Diclofenac; Humans; Ibuprofen; Lipids; Naproxen | 2022 |
Ibuprofen, Ketorolac, and Diclofenac Are Equivalent for the Treatment of Acute, Nonradicular Low Back Pain.
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Ketorolac; Low Back Pain | 2022 |
Metabolism of non-steroidal anti-inflammatory drugs (NSAIDs) by Streptomyces griseolus CYP105A1 and its variants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacterial Proteins; Cytochrome P-450 Enzyme System; Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Meclofenamic Acid; Mefenamic Acid; Streptomyces | 2022 |
The impact of sewage sludge processing on the safety of its use.
Topics: Carbamazepine; Diclofenac; Ecosystem; Ethinyl Estradiol; Fertilizers; Ibuprofen; Pharmaceutical Preparations; Sewage; Soil; Soil Pollutants; Water; Water Pollutants, Chemical | 2022 |
Highly sensitive and simultaneous electrochemical determinations of non-steroidal anti-inflammatory drugs in water using nanostructured carbon-based paste electrodes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrochemical Techniques; Electrodes; Fullerenes; Graphite; Ibuprofen; Nanotubes, Carbon; Naproxen; Reproducibility of Results | 2022 |
Non-steroidal anti-inflammatory drugs and risk of myocardial infarction adjusting for use of proton pump-inhibitors in patients with no major risk factors: a nested case-control study in the UK Clinical Practice Research Datalink.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Diclofenac; Humans; Ibuprofen; Myocardial Infarction; Proton Pump Inhibitors; Proton Pumps; United Kingdom | 2022 |
Rapid determination of NSAIDs by capillary and microchip electrophoresis with capacitively coupled contactless conductivity detection in wastewater.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Electric Conductivity; Electrophoresis, Capillary; Electrophoresis, Microchip; Ibuprofen; Ketoprofen; Methanol; Pharmaceutical Preparations; Wastewater | 2022 |
Non-steroidal anti-inflammatory drugs caused an outbreak of inflammation and oxidative stress with changes in the gut microbiota in rainbow trout (Oncorhynchus mykiss).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Diclofenac; Disease Outbreaks; Dysbiosis; Ecosystem; Gastrointestinal Microbiome; HSP70 Heat-Shock Proteins; Ibuprofen; Inflammation; Oncorhynchus mykiss; Oxidative Stress; Oxygen; Pharmaceutical Preparations; Reactive Oxygen Species; RNA, Messenger; Water; Water Pollutants, Chemical | 2022 |
Medicine-Induced Acute Kidney Injury Findings from Spontaneous Reporting Systems, Sequence Symmetry Analysis and a Case-Control Study with a Focus on Medicines Used in Primary Care.
Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Amlodipine; Amphotericin B; Australia; Case-Control Studies; Ciprofloxacin; Diclofenac; Furosemide; Humans; Ibuprofen; Metformin; Naproxen; Omeprazole; Primary Health Care; Ramipril; Simvastatin; Spironolactone; Sulfamethoxazole; Telmisartan; Trimethoprim; Valacyclovir; Zoledronic Acid | 2022 |
2022 Taiwan Guidelines for Acute Treatment of Migraine.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin Gene-Related Peptide Receptor Antagonists; Child; Diclofenac; Female; Headache; Humans; Ibuprofen; Migraine Disorders; Morphine Derivatives; Naproxen; Nasal Sprays; Pregnancy; Prochlorperazine; Taiwan; Tramadol; Tryptamines | 2022 |
Pharmaceuticals, natural and synthetic hormones and phenols in sediments from an eutrophic estuary, Jurujuba Sound, Guanabara Bay, Brazil.
Topics: Bays; Brazil; Diclofenac; Endocrine Disruptors; Environmental Monitoring; Estradiol; Estriol; Estrogens; Estrone; Estuaries; Gemfibrozil; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenols; Water Pollutants, Chemical | 2022 |
NSAIDs affect dendritic cell cytokine production.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Neoplasm; CD8-Positive T-Lymphocytes; Celecoxib; Cytokines; Dendritic Cells; Diclofenac; Humans; Ibuprofen; Mice; Neoplasms | 2022 |
Preclinical comparison of antinociceptive effects between ibuprofen, diclofenac, naproxen, and acetaminophen on acid-stimulated body stretching and acid-depressed feeding behaviors in rats.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Feeding Behavior; Ibuprofen; Lactic Acid; Male; Naproxen; Pain; Rats | 2022 |
Impact of Voltage Application on Degradation of Biorefractory Pharmaceuticals in an Anaerobic-Aerobic Coupled Upflow Bioelectrochemical Reactor.
Topics: Anaerobiosis; Bioreactors; Carbamazepine; Diclofenac; Ecosystem; Ibuprofen; Pharmaceutical Preparations; Waste Disposal, Fluid; Water Pollutants, Chemical | 2022 |
Selective enrichment, identification, and isolation of diclofenac, ibuprofen, and carbamazepine degrading bacteria from a groundwater biofilm.
Topics: Bacteria; Biodegradation, Environmental; Biofilms; Carbamazepine; Diclofenac; Ecosystem; Groundwater; Ibuprofen; Pharmaceutical Preparations | 2023 |
3D-printed EVA-based patches manufactured by direct powder extrusion for personalized transdermal therapies.
Topics: Diclofenac; Drug Liberation; Humans; Ibuprofen; Powders; Printing, Three-Dimensional; Spectroscopy, Fourier Transform Infrared; Tablets | 2023 |
Evaluation of the Defined Bacterial Consortium Efficacy in the Biodegradation of NSAIDs.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Naproxen; Sewage | 2023 |
Impact of Lifestyle and Socioeconomic Position on the Association Between Non-steroidal Anti-inflammatory Drug Use and Major Adverse Cardiovascular Events: A Case-Crossover Study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cross-Over Studies; Diclofenac; Humans; Ibuprofen; Life Style; Myocardial Infarction; Naproxen; Risk Factors; Socioeconomic Factors | 2023 |
Advanced oxidation and a metrological strategy based on CLC-MS for the removal of pharmaceuticals from pore & surface water.
Topics: Diclofenac; Ibuprofen; Ketoprofen; Pharmaceutical Preparations; Water; Water Pollutants, Chemical | 2023 |
Impact of hemoglobin A1c level on the association between non-steroidal anti-inflammatory drug use and cardiovascular events in patients with type 2 diabetes: A population-based cohort study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Diabetes Mellitus, Type 2; Diclofenac; Glycated Hemoglobin; Humans; Ibuprofen; Myocardial Infarction; Naproxen; Risk Factors | 2023 |
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Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Environmental Pollutants; Humans; Ibuprofen; Ligands; Metal-Organic Frameworks; Water | 2023 |
Cardiovascular risks of continuing vs. initiating NSAIDs after first-time myocardial infarction or heart failure: a nationwide cohort study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cohort Studies; Diclofenac; Heart Disease Risk Factors; Heart Failure; Humans; Ibuprofen; Myocardial Infarction; Naproxen; Risk Factors | 2023 |
Health risk assessment for uptake and accumulation of pharmaceuticals in jute mallow (Corchorus olitorius) irrigated with treated hospital wastewater.
Topics: Acetaminophen; Agricultural Irrigation; Anti-Bacterial Agents; Ciprofloxacin; Corchorus; Diclofenac; Environmental Monitoring; Humans; Ibuprofen; Pharmaceutical Preparations; Risk Assessment; Soil; Soil Pollutants; Sulfamethoxazole; Tetracyclines; Wastewater; Water | 2023 |
Effect of salinity on the toxicity of diclofenac, ibuprofen and naproxen toward cyanobacterium Synechocystis salina.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Naproxen; Salinity; Water Pollutants, Chemical | 2023 |
Green UPLC method for estimation of ciprofloxacin, diclofenac sodium, and ibuprofen with application to pharmacokinetic study of human samples.
Topics: Acetonitriles; Chromatography, High Pressure Liquid; Ciprofloxacin; Diclofenac; Humans; Ibuprofen; Reproducibility of Results; Tandem Mass Spectrometry | 2023 |