Compounds > diclofenac

diclofenac and geranylgeranylacetone

diclofenac has been researched along with geranylgeranylacetone in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Hyodo, I; Matsui, H; Nakahara, A; Sato, D; Shibahara, T; Suzuki, H; Tauchi, M; Yanaka, A; Zhang, S1
Ando, T; Goto, H; Hirooka, Y; Itoh, A; Kawashima, H; Miyahara, R; Nakamura, M; Niwa, Y; Ohmiya, N; Watanabe, O1
Higuchi, K; Inoue, T; Ishida, K; Kojima, Y; Kuramoto, T; Nouda, S; Takeuchi, T; Tokioka, S; Umegaki, E1
Chen, M; Huang, X; Li, L; Liang, L; Xiong, L; Yang, X; Ye, Y; Zhan, Z1
Chao, G; Qian, Y; Wang, Z; Yang, C; Zhang, S1

Trials

4 trial(s) available for diclofenac and geranylgeranylacetone

ArticleYear
Geranylgeranylacetone protects the human gastric mucosa from diclofenac-induced injury via induction of heat shock protein 70.
    Digestion, 2007, Volume: 75, Issue:2-3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Apoptosis; Biopsy; Diclofenac; Diterpenes; DNA Damage; Enzyme-Linked Immunosorbent Assay; Female; Gastric Mucosa; Gastroscopy; HSP70 Heat-Shock Proteins; Humans; Male; Stomach Ulcer; Treatment Outcome; Up-Regulation

2007
Geranylgeranylacetone protects against diclofenac-induced gastric and small intestinal mucosal injuries in healthy subjects: a prospective randomized placebo-controlled double-blind cross-over study.
    Digestion, 2009, Volume: 80, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Cross-Over Studies; Diclofenac; Diterpenes; Double-Blind Method; Humans; Male; Peptic Ulcer; Prospective Studies; Rabeprazole; Young Adult

2009
Geranylgeranylacetone, a gastromucoprotective drug, protects against NSAID-induced esophageal, gastroduodenal and small intestinal mucosal injury in healthy subjects: A prospective randomized study involving a comparison with famotidine.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Diclofenac; Diterpenes; Endoscopy, Digestive System; Esophagus; Famotidine; Gastric Mucosa; Humans; Intestinal Mucosa; Leukocyte L1 Antigen Complex; Male; Prospective Studies; Young Adult

2014
Geranylgeranylacetone protects against small-intestinal injuries induced by diclofenac in patients with rheumatic diseases: a prospective randomized study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2015, Volume: 47, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsule Endoscopy; Diclofenac; Diterpenes; Female; Follow-Up Studies; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Prospective Studies; Rheumatic Diseases

2015

Other Studies

1 other study(ies) available for diclofenac and geranylgeranylacetone

ArticleYear
Teprenone ameliorates diclofenac-induced small intestinal injury via inhibiting protease activated receptors 1 and 2 activity.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2021, Volume: 26, Issue:1

    Topics: Abdominal Injuries; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Disease Models, Animal; Diterpenes; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestine, Small; Microscopy, Electron, Transmission; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, PAR-2

2021