diclofenac has been researched along with gemfibrozil in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (24.32) | 29.6817 |
| 2010's | 25 (67.57) | 24.3611 |
| 2020's | 3 (8.11) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Galetin, A; Gill, KL; Houston, JB | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Furukawa, T; Hosoya, K; Kadono, K; Moriguchi, H; Nakamori, F; Naritomi, Y; Teramura, T; Terashita, S; Tetsuka, K; Yamano, K | 1 |
| Anan, I; Begum, A; Brännström, K; Gharibyan, AL; Iakovleva, I; Nilsson, L; Olofsson, A; Sauer-Eriksson, AE; Walfridsson, M | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Darvesh, AS; Geldenhuys, WJ; Leeper, TC; Morris, DL; Sullivan, PG; Yonutas, HM | 1 |
| Dalvie, D; Fu, Y; Khojasteh, SC; Ma, Y; Zhang, D | 1 |
| Khan, AI; Lei, L; Norquist, AJ; O'Hare, D | 1 |
| Porte, C; Schnell, S; Thibaut, R | 1 |
| Kołodziejczyk, MK; Lukosek, M; Nachajski, MJ; Woskowicz, MH; Zgoda, MM | 1 |
| Nogueira, JM; Portugal, FC; Silva, AR | 1 |
| Asami, M; Fujiwara, J; Kunikane, S; Manabe, S; Matsuda, M; Simazaki, D | 1 |
| Binelli, A; Parolini, M; Provini, A; Quinn, B | 1 |
| Hernan, R; O'Rourke, K; Quinn, B; Schmidt, W | 2 |
| Fernandes, D; Porte, C; Schnell, S | 1 |
| Bragg, LM; Dixon, G; Oakes, KD; Pawliszyn, J; Servos, MR; Wang, S | 1 |
| Coleman, HM; Khan, SJ; Le-Clech, P; Stuetz, RM; Trinh, T; van den Akker, B | 1 |
| McEneff, G; Quinn, B; Rainville, LC; Schmidt, W; Sheehan, D | 1 |
| Gagnon, GA; Krkošek, WH; Payne, SJ | 1 |
| Ribalta, C; Solé, M | 1 |
| Ademollo, N; Capri, S; Patrolecco, L | 1 |
| Alidina, M; Drewes, JE; Shewchuk, J | 1 |
| Gjelstad, A; Pedersen-Bjergaard, S; Roldán-Pijuán, M | 1 |
| Bilkis, II; Kohay, H; Mishael, YG | 1 |
| Gu, Y; Mei, X; Sui, Q; Wu, D; Yu, X; Zhao, W | 1 |
| Bila, DM; da Fonseca, EM; da Silva de Freitas, A; de Oliveira Santos, AD; do Nascimento, MTL; Dos Santos, RF; Felix, LC; Hauser-Davis, RA; Neto, JAB; Sanson, AL | 1 |
| Gálvez-Rodríguez, A; Kumar, M; Mohapatra, S; Mukherji, S; Padhye, LP; Shea, P; Snow, D | 1 |
2 review(s) available for diclofenac and gemfibrozil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Glucuronides as Potential Anionic Substrates of Human Cytochrome P450 2C8 (CYP2C8).
Topics: Anions; Binding Sites; Cytochrome P-450 CYP2C8; Drug Interactions; Glucuronides; Humans; Ligands | 2017 |
35 other study(ies) available for diclofenac and gemfibrozil
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Characterization of in vitro glucuronidation clearance of a range of drugs in human kidney microsomes: comparison with liver and intestinal glucuronidation and impact of albumin.
Topics: Adult; Aged; Female; Glucuronides; Glucuronosyltransferase; Humans; In Vitro Techniques; Intestinal Mucosa; Intestines; Kidney; Liver; Male; Metabolic Clearance Rate; Microsomes; Middle Aged; Organ Specificity; Pharmaceutical Preparations; Predictive Value of Tests; Protein Binding; Serum Albumin, Bovine; Substrate Specificity; Young Adult | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Quantitative prediction of human intestinal glucuronidation effects on intestinal availability of UDP-glucuronosyltransferase substrates using in vitro data.
Topics: Administration, Oral; Biotransformation; Cell Membrane Permeability; Cytochrome P-450 Enzyme System; Glucuronides; Glucuronosyltransferase; Humans; Intestinal Absorption; Intestines; Isoenzymes; Kinetics; Metabolic Clearance Rate; Microsomes; Models, Biological; Pharmaceutical Preparations; Recombinant Proteins; Substrate Specificity | 2012 |
Enthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma.
Topics: Amyloidosis; Calorimetry; Drug Design; Humans; Ligands; Models, Molecular; Plasma; Prealbumin; Protein Binding; Thermodynamics; X-Ray Diffraction | 2015 |
Identification of small molecules that bind to the mitochondrial protein mitoNEET.
Topics: Hypoglycemic Agents; Ligands; Mitochondrial Proteins; Protein Binding; Small Molecule Libraries; Thiazolidinediones | 2016 |
Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Gemfibrozil; Hydrogen-Ion Concentration; Hydroxides; Ibuprofen; Naproxen; ortho-Aminobenzoates; Phenylacetates; Valproic Acid | 2001 |
The interference of pharmaceuticals with endogenous and xenobiotic metabolizing enzymes in carp liver: an in-vitro study.
Topics: Animals; Antidepressive Agents; Carps; Catalysis; Clofibric Acid; Diclofenac; Gemfibrozil; Lipids; Liver; Liver Extracts; Pharmaceutical Preparations; Subcellular Fractions; Sulfotransferases; Xenobiotics | 2006 |
Solubilizing properties of new surface-active agents, products of selective oxyethylation of cholic acid. Part I.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chlorates; Diclofenac; Fenofibrate; Gemfibrozil; Hypolipidemic Agents; Ketoprofen; Micelles; Models, Theoretical; Nifedipine; Solubility; Solutions; Surface-Active Agents; Vasodilator Agents; Viscosity | 2007 |
Advances in stir bar sorptive extraction for the determination of acidic pharmaceuticals in environmental water matrices Comparison between polyurethane and polydimethylsiloxane polymeric phases.
Topics: Chromatography, High Pressure Liquid; Diclofenac; Dimethylpolysiloxanes; Gemfibrozil; Ibuprofen; Mefenamic Acid; Naproxen; Polyurethanes; Reproducibility of Results; Water Pollutants, Chemical; Water Purification | 2008 |
Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.
Topics: Antipyrine; Charcoal; Clofibric Acid; Diclofenac; Fenoprofen; Gemfibrozil; Halogenation; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Water Pollutants, Chemical; Water Purification; Water Supply | 2008 |
Cytotoxicity assessment of four pharmaceutical compounds on the zebra mussel (Dreissena polymorpha) haemocytes, gill and digestive gland primary cell cultures.
Topics: Animals; Atenolol; Carbamazepine; Cells, Cultured; Diclofenac; Digestive System; Dreissena; Gemfibrozil; Gills; Hemocytes; Prescription Drugs; Water Pollutants, Chemical | 2011 |
Effects of the pharmaceuticals gemfibrozil and diclofenac on biomarker expression in the zebra mussel (Dreissena polymorpha) and their comparison with standardised toxicity tests.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Araceae; Biomarkers; Chlorophyta; Daphnia; Diclofenac; Dreissena; Gemfibrozil; Glutathione Transferase; Hypolipidemic Agents; Lipid Peroxidation; Toxicity Tests; Water Pollutants, Chemical | 2011 |
Effects of the pharmaceuticals gemfibrozil and diclofenac on the marine mussel (Mytilus spp.) and their comparison with standardized toxicity tests.
Topics: Aliivibrio fischeri; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Diclofenac; Gemfibrozil; Glutathione Transferase; Hypolipidemic Agents; Lipid Peroxidation; Metallothionein; Mytilus; Toxicity Tests; Water Pollutants, Chemical | 2011 |
Can pharmaceuticals interfere with the synthesis of active androgens in male fish? An in vitro study.
Topics: Androgens; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Biomarkers; Carps; Clofibrate; Clofibric Acid; Diclofenac; Fibric Acids; Fluoxetine; Gemfibrozil; Ibuprofen; Male; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase; Testis; Water Pollutants, Chemical | 2011 |
Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish.
Topics: Animals; Atrazine; Benzhydryl Compounds; Carbamazepine; Diclofenac; Environmental Monitoring; Fishes; Fluoxetine; Gemfibrozil; Ibuprofen; Naproxen; Phenols; Solid Phase Extraction; Solid Phase Microextraction; Waste Disposal, Fluid; Water Pollutants, Chemical | 2011 |
Removal of trace organic chemical contaminants by a membrane bioreactor.
Topics: Amitriptyline; Bioreactors; Carbamazepine; Diazepam; Diclofenac; Fluoxetine; Gemfibrozil; Omeprazole; Organic Chemicals; Pharmaceutical Preparations; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Pollutants, Chemical | 2012 |
A proteomic evaluation of the effects of the pharmaceuticals diclofenac and gemfibrozil on marine mussels (Mytilus spp.): evidence for chronic sublethal effects on stress-response proteins.
Topics: Animals; Chromatography, Liquid; Diclofenac; Energy Metabolism; Gemfibrozil; Heat-Shock Proteins; Mytilus; Oxidative Stress; Proteome; Proteomics; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2014 |
Removal of acidic pharmaceuticals within a nitrifying recirculating biofilter.
Topics: Adsorption; Bacteria; Biofilms; Diclofenac; DNA, Bacterial; Filtration; Gemfibrozil; Genes, Bacterial; Ibuprofen; Naproxen; Nitrification; Waste Disposal, Fluid; Water Pollutants, Chemical | 2014 |
In vitro interaction of emerging contaminants with the cytochrome p450 system of Mediterranean deep-sea fish.
Topics: Animals; Benzopyrans; Cytochrome P-450 Enzyme System; Diclofenac; Female; Fish Proteins; Fishes; Fluoxetine; Gemfibrozil; Male; Mediterranean Sea; Phenols; Triclosan; Water Pollutants, Chemical; Xenobiotics | 2014 |
Occurrence of selected pharmaceuticals in the principal sewage treatment plants in Rome (Italy) and in the receiving surface waters.
Topics: Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Estrone; Gemfibrozil; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Rome; Seasons; Solid Phase Extraction; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
Effect of temperature on removal of trace organic chemicals in managed aquifer recharge systems.
Topics: Benzophenones; Diclofenac; Gemfibrozil; Groundwater; Ketoprofen; Naproxen; Soil Microbiology; Temperature; Trimethoprim; Water Pollutants, Chemical | 2015 |
Parallel artificial liquid membrane extraction of acidic drugs from human plasma.
Topics: Calibration; Chromatography, High Pressure Liquid; Diclofenac; Equipment Design; Flurbiprofen; Gemfibrozil; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Liquid-Liquid Extraction; Membranes, Artificial; Pharmaceutical Preparations; Polypropylenes; Polyvinyls | 2015 |
Effect of polycation charge density on polymer conformation at the clay surface and consequently on pharmaceutical binding.
Topics: Adsorption; Diclofenac; Gemfibrozil; Molecular Conformation; Particle Size; Polyamines; Polyelectrolytes; Polymers; Surface Properties | 2019 |
Non-antibiotics matter: Evidence from a one-year investigation of livestock wastewater from six farms in East China.
Topics: Animals; Anti-Bacterial Agents; Cattle; China; DEET; Diclofenac; Environmental Monitoring; Farms; Gemfibrozil; Livestock; Pharmaceutical Preparations; Swine; Wastewater; Water Pollutants, Chemical | 2022 |
Pharmaceuticals, natural and synthetic hormones and phenols in sediments from an eutrophic estuary, Jurujuba Sound, Guanabara Bay, Brazil.
Topics: Bays; Brazil; Diclofenac; Endocrine Disruptors; Environmental Monitoring; Estradiol; Estriol; Estrogens; Estrone; Estuaries; Gemfibrozil; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenols; Water Pollutants, Chemical | 2022 |
Photodegradation of a mixture of five pharmaceuticals commonly found in wastewater: Experimental and computational analysis.
Topics: Acetaminophen; Carbamazepine; Carbon; Diclofenac; Gemfibrozil; Pharmaceutical Preparations; Photolysis; Sulfamethoxazole; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2023 |