diclofenac and furosemide

diclofenac has been researched along with furosemide in 58 studies

Research

Studies (58)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (5.17)	18.7374
1990's	2 (3.45)	18.2507
2000's	21 (36.21)	29.6817
2010's	29 (50.00)	24.3611
2020's	3 (5.17)	2.80

Authors

Authors	Studies
Cha, SH; Endou, H; Kanai, Y; Kim, DK; Kim, JY; Kusuhara, H; Sekine, T; Sugiyama, Y; Yu, E	1
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T	1
Chang, TK; Ensom, MH; Kiang, TK	1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A	1
Jolivette, LJ; Ward, KW	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Avdeef, A; Tam, KY	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA	1
Bellman, K; Knegtel, RM; Settimo, L	1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y	1
Goetz, GH; Philippe, L; Shapiro, MJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Darvesh, AS; Geldenhuys, WJ; Leeper, TC; Morris, DL; Sullivan, PG; Yonutas, HM	1
Abu-Serie, MM; AlFadly, ED; Bakkar, NZ; Bartolini, M; Belal, ASF; El-Yazbi, AF; Elkazaz, S; Elzahhar, PA; Ghareeb, DA; Iriepa, I; Janockova, J; Kobeissy, F; Moraleda, I; Rafeh, RW; Saudi, MNS; Shaltout, H; Soukup, O; Tramarin, A	1
Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K	1
Barlow, JW; Lim, CF; Raggatt, LE; Stockigt, JR; Topliss, DJ	1
Benvenga, S; Cahnmann, HJ; Gregg, RE; Robbins, J	1
Benvenga, S; Li Calzi, L; Robbins, J	1
Hamblin, PS; Kolliniatis, E; Lim, CF; Stockigt, JR; Topliss, DJ	1
Benvenga, S; Cahnmann, HJ; Robbins, J	1
Karami-Tehrani, F; Mokarram, P; Salami, S	1
Mannesse, CK; van der Cammen, TJ	1
Bogolepova, AE; Shakhmatova, EI	1
Masumoto, H; Mitsuru, A; Okazaki, O; Sudo, K; Takakusa, H	1
Balal, M; Besen, A; Dogan, A; Gonlusen, G; Inal, T; Kibar, M; Kose, F; Paydas, S	1
Marison, IW; von Stockar, U; Whelehan, M	1
Efentakis, M; Naseef, H; Vlachou, M	1
Jacobs, D; McGuinness, N; Paterson, CA; Rasmussen, S; Youngberg, SP	1
Abramczuk, E; Hryniewiecki, T; Jaworska-Wilczynska, M	1
Correia, AT; Guimarães, LL; Roveri, V; Toma, W	1
Kassie, GM; Kerr, M; Moffat, A; Pratt, N; Roughead, EE	1
Biegert, C; Günaydin, I; Heide, L; Kötter, I; Lohmüller, C; Lüdtke, R; Taxis, K; Wagner, I	1
Bonaterra, GA; Kelber, O; Kinscherf, R; Metz, J; Weiser, D	1

Reviews

3 review(s) available for diclofenac and furosemide

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for diclofenac and furosemide

Article	Year
Randomized, open-label, 5-way crossover study to evaluate the pharmacokinetic/pharmacodynamic interaction between furosemide and the non-steroidal anti-inflammatory drugs diclofenac and ibuprofen in healthy volunteers. International journal of clinical pharmacology and therapeutics, 2011, Volume: 49, Issue:8 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Cross-Over Studies; Diclofenac; Diuretics; Drug Interactions; Female; Furosemide; Humans; Ibuprofen; Male; Middle Aged; Transdermal Patch; Young Adult	2011
Efficacy and safety of willow bark extract in the treatment of osteoarthritis and rheumatoid arthritis: results of 2 randomized double-blind controlled trials. The Journal of rheumatology, 2004, Volume: 31, Issue:11 Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Female; Health Status; Humans; Male; Middle Aged; Osteoarthritis; Plant Bark; Plant Extracts; Salix; Severity of Illness Index; Treatment Outcome	2004

Article

Year

Randomized, open-label, 5-way crossover study to evaluate the pharmacokinetic/pharmacodynamic interaction between furosemide and the non-steroidal anti-inflammatory drugs diclofenac and ibuprofen in healthy volunteers.

International journal of clinical pharmacology and therapeutics, 2011, Volume: 49, Issue:8

Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Cross-Over Studies; Diclofenac; Diuretics; Drug Interactions; Female; Furosemide; Humans; Ibuprofen; Male; Middle Aged; Transdermal Patch; Young Adult

2011

Efficacy and safety of willow bark extract in the treatment of osteoarthritis and rheumatoid arthritis: results of 2 randomized double-blind controlled trials.

The Journal of rheumatology, 2004, Volume: 31, Issue:11

Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Female; Health Status; Humans; Male; Middle Aged; Osteoarthritis; Plant Bark; Plant Extracts; Salix; Severity of Illness Index; Treatment Outcome

2004

Other Studies

53 other study(ies) available for diclofenac and furosemide

Article	Year
Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. The Journal of biological chemistry, 2000, Feb-11, Volume: 275, Issue:6 Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; Cloning, Molecular; Dehydroepiandrosterone Sulfate; Estrone; Humans; Kidney; Kinetics; Membrane Proteins; Molecular Sequence Data; Ochratoxins; Oocytes; Placenta; RNA, Messenger; Sequence Alignment; Sulfates; Xenopus	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Molecular pharmacology, 2001, Volume: 59, Issue:5 Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis	2001
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism	2005
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Glutathione; Pharmacology; Sulfur Radioisotopes	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index	2014
EPSA: A Novel Supercritical Fluid Chromatography Technique Enabling the Design of Permeable Cyclic Peptides. ACS medicinal chemistry letters, 2014, Oct-09, Volume: 5, Issue:10 Topics:	2014
Identification of small molecules that bind to the mitochondrial protein mitoNEET. Bioorganic & medicinal chemistry letters, 2016, 11-01, Volume: 26, Issue:21 Topics: Hypoglycemic Agents; Ligands; Mitochondrial Proteins; Protein Binding; Small Molecule Libraries; Thiazolidinediones	2016
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase. European journal of medicinal chemistry, 2019, Apr-01, Volume: 167 Topics: Acetylcholine; Alzheimer Disease; Animals; Cell Line; Cholinesterase Inhibitors; Cyclooxygenase 2 Inhibitors; Drug Design; Humans; Inflammation; Lipoxygenase Inhibitors; Mice; Molecular Docking Simulation; Neurons; PC12 Cells; Rats; Semicarbazides; Triazoles	2019
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design. Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4 Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry	2020
Characterization of cytoplasmic T3 binding sites by adsorption to hydroxyapatite: effects of drug inhibitors of T3 and relationship to glutathione-S-transferases. Thyroid : official journal of the American Thyroid Association, 1992,Spring, Volume: 2, Issue:1 Topics: Amiodarone; Animals; Binding Sites; Binding, Competitive; Cytosol; Diclofenac; Dithiothreitol; Dose-Response Relationship, Drug; Durapatite; Furosemide; Glutathione Transferase; Hydrocortisone; Hydroxyapatites; In Vitro Techniques; Iopanoic Acid; Liver; Macaca fascicularis; Mefenamic Acid; Sulfobromophthalein; Taurocholic Acid; Triiodothyronine	1992
Characterization of the binding of thyroxine to high density lipoproteins and apolipoproteins A-I. The Journal of clinical endocrinology and metabolism, 1989, Volume: 68, Issue:6 Topics: Apolipoprotein A-I; Apolipoproteins A; Autoradiography; Binding Sites; Diclofenac; Furosemide; Lipoproteins, HDL; Lipoproteins, VLDL; Mefenamic Acid; Temperature; Thyroid Hormones; Thyroxine; Thyroxine-Binding Proteins; Time Factors	1989
Effect of free fatty acids and nonlipid inhibitors of thyroid hormone binding in the immunoradiometric assay of thyroxin-binding globulin. Clinical chemistry, 1987, Volume: 33, Issue:10 Topics: Binding, Competitive; Diclofenac; False Negative Reactions; Fatty Acids, Nonesterified; Furosemide; Humans; Mefenamic Acid; Phenylacetates; Radioimmunoassay; Reagent Kits, Diagnostic; Thyroxine; Thyroxine-Binding Proteins	1987
Furosemide, fenclofenac, diclofenac, mefenamic acid and meclofenamic acid inhibit specific T3 binding in isolated rat hepatic nuclei. Journal of endocrinological investigation, 1988, Volume: 11, Issue:5 Topics: Amiodarone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Nucleus; Diclofenac; Furosemide; In Vitro Techniques; Liver; Male; Meclofenamic Acid; Mefenamic Acid; Phenylacetates; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Thyroid Hormone	1988
Characterization of thyroid hormone binding to apolipoprotein-E: localization of the binding site in the exon 3-coded domain. Endocrinology, 1993, Volume: 133, Issue:3 Topics: Affinity Labels; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Apolipoproteins E; Binding Sites; Blood Proteins; Diclofenac; Exons; Furosemide; Isoelectric Focusing; Mefenamic Acid; Mice; Molecular Sequence Data; Mutation; Photochemistry; Thyroxine	1993
Competition of tamoxifen with thyroxine for TBG binding: ligand binding assay and computational data. Clinical biochemistry, 2001, Volume: 34, Issue:8 Topics: Binding, Competitive; Diclofenac; Furosemide; Humans; Mefenamic Acid; Models, Molecular; Molecular Conformation; Tamoxifen; Thyroxine; Thyroxine-Binding Proteins	2001
[Adverse drug reactions in three older patients, even without changes in medication]. Nederlands tijdschrift voor geneeskunde, 2003, Mar-29, Volume: 147, Issue:13 Topics: Adverse Drug Reaction Reporting Systems; Aged; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Diclofenac; Digoxin; Diuretics; Drug Interactions; Female; Furosemide; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Hypotension, Orthostatic; Kidney; Male; Quinidine; Urinary Bladder Neoplasms	2003
[Role of prostaglandin E2 in regulation of urine excretion in saluresis, water and osmotic diuresis in rat]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2004, Volume: 90, Issue:11 Topics: Animals; Celecoxib; Chlorides; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Diuresis; Diuretics; Furosemide; Male; Natriuresis; Osmosis; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Urination; Water	2004
Markers of electrophilic stress caused by chemically reactive metabolites in human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:5 Topics: Acetaminophen; Aspirin; Butylated Hydroxyanisole; Carboxylic Ester Hydrolases; Cells, Cultured; Clozapine; Diclofenac; Furosemide; Glucuronosyltransferase; Heme Oxygenase-1; Hepatocytes; Humans; L-Lactate Dehydrogenase; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; RNA, Messenger; Ticlopidine; Ticrynafen	2008
The effects of the nonsteroidal anti-inflammatory drug diclofenac sodium on the rat kidney, and alteration by furosemide. International urology and nephrology, 2009, Volume: 41, Issue:4 Topics: Acute Kidney Injury; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Needle; Creatinine; Cyclooxygenase 1; Cyclooxygenase 2; Diclofenac; Disease Models, Animal; Drug Therapy, Combination; Furosemide; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Probability; Random Allocation; Rats; Rats, Wistar; Reference Values; Urinalysis	2009
Removal of pharmaceuticals from water: using liquid-core microcapsules as a novel approach. Water research, 2010, Volume: 44, Issue:7 Topics: Capsules; Carbamazepine; Clofibric Acid; Diclofenac; Environmental Monitoring; Feasibility Studies; Fresh Water; Furosemide; Kinetics; Metoprolol; Pharmaceutical Preparations; Reproducibility of Results; Sulfamethoxazole; Warfarin; Water Pollutants, Chemical; Water Purification; Water Supply	2010
Two- and three-layer tablet drug delivery systems for oral sustained release of soluble and poorly soluble drugs. Drug development and industrial pharmacy, 2010, Volume: 36, Issue:8 Topics: Administration, Oral; Delayed-Action Preparations; Diclofenac; Diffusion; Drug Carriers; Drug Compounding; Drug Delivery Systems; Furosemide; Hydrophobic and Hydrophilic Interactions; Kinetics; Polymers; Solubility; Tablets; Water	2010
Postcardiac injury syndrome. Medical science monitor : international medical journal of experimental and clinical research, 2011, Volume: 17, Issue:11 Topics: Cardiac Tamponade; Coronary Artery Bypass; Diclofenac; Diuretics; Echocardiography; Furosemide; Humans; Male; Pericardiocentesis; Pericarditis; Postpericardiotomy Syndrome; Prednisone	2011
Occurrence, ecological risk assessment and prioritization of pharmaceuticals and abuse drugs in estuarine waters along the São Paulo coast, Brazil. Environmental science and pollution research international, 2022, Volume: 29, Issue:59 Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Diclofenac; Ecosystem; Environmental Monitoring; Furosemide; Illicit Drugs; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical	2022
Medicine-Induced Acute Kidney Injury Findings from Spontaneous Reporting Systems, Sequence Symmetry Analysis and a Case-Control Study with a Focus on Medicines Used in Primary Care. Drug safety, 2022, Volume: 45, Issue:11 Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Amlodipine; Amphotericin B; Australia; Case-Control Studies; Ciprofloxacin; Diclofenac; Furosemide; Humans; Ibuprofen; Metformin; Naproxen; Omeprazole; Primary Health Care; Ramipril; Simvastatin; Spironolactone; Sulfamethoxazole; Telmisartan; Trimethoprim; Valacyclovir; Zoledronic Acid	2022
In vitro anti-proliferative effects of the willow bark extract STW 33-I. Arzneimittel-Forschung, 2010, Volume: 60, Issue:6 Topics: Apoptosis; Aspirin; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Diclofenac; Humans; L-Lactate Dehydrogenase; Plant Bark; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; Salix	2010