diclofenac has been researched along with flurbiprofen in 125 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (11.20) | 18.7374 |
| 1990's | 43 (34.40) | 18.2507 |
| 2000's | 33 (26.40) | 29.6817 |
| 2010's | 29 (23.20) | 24.3611 |
| 2020's | 6 (4.80) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Cihlar, T; Ho, ES; Mulato, AS | 1 |
| Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Carrupt, PA; Martel, S; Ottaviani, G | 1 |
| Blobaum, AL; Marnett, LJ | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Arsequell, G; Blasi, D; Bosch, L; Centeno, NB; Cotrina, EY; Pinto, M; Planas, A; Quintana, J; Valencia, G; Vilà, M | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Boreddy, TS; Karpoormath, R; Palkar, MB; Rane, RA; Ronad, PM; Shaikh, MS; Singhai, AS; Veerapur, VP; Vishwanathswamy, AH | 1 |
| Headey, SJ; Hughes, ML; Laguerre, A; Mohanty, B; Patil, R; Porter, CJ; Scanlon, MJ; Wielens, J; Williams, ML | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Amodeo, C; De Marco, M; Gambarini, G | 1 |
| Bellamy, N; Bensen, WG; Ford, PM; Huang, SH; Lang, JY | 1 |
| Asproudis, I; Kalogeropoulos, C; Loucatzicos, E; Petroutsos, G; Psilas, K | 1 |
| Pradalier, A; Vincent, D | 1 |
| Mindel, JS | 1 |
| VanArsdel, PP | 1 |
| Fernandes, G; Flescher, E; Fossum, D; Gray, PJ; Harper, MJ; Talal, N | 1 |
| Bellamy, N; Campbell, J; Wells, G | 1 |
| Atra, E; Brown, BL; Metz, CA; Teoh, K | 1 |
| Baer, JC; Foster, CS; Hersh, PS; Lynch, SE; McGuigan, LJ; Rice, BA; Wells, PA | 1 |
| Barlow, WE; McGuigan, LJ; Trousdale, MD | 1 |
| Masuda, K; Mishima, H; Miyake, K | 1 |
| Frame, JW; Rout, PG | 1 |
| de Jong, PE; de Zeeuw, D; Donker, AJ; Pratt, JJ; van der Hem, GK; Vriesendorp, R | 1 |
| Hertting, G; Knepel, W; Vlaskovska, M | 1 |
| Benvenuti, C; Guidoni, G; Longoni, A; Mordini, M | 1 |
| Famaey, JP; Ginsberg, F | 1 |
| Baumüller, A; Esders, K | 1 |
| Araie, M; Sawa, M; Takase, M | 1 |
| Aizawa, Y; Hasegawa, N; Inazu, N; Kogo, H; Takeuchi, K; Yamada, K; Yoshida, Y | 1 |
| Förstermann, U; Heldt, R; Hertting, G; Knappen, F | 1 |
| Schöpp, W | 1 |
| Glasius, E; Noach, EL; Oosterhuis, JA; van Delft, JL; van Haeringen, NJ | 1 |
| al Reaves, T; Koester, JM; McCarey, BE; Napalkov, JA; Pippen, PA | 1 |
| Chemtob, S; Hanna, N; Lachapelle, P; Orquin, J; Roy, MS; Varma, DR | 1 |
| Bloedow, DC; Ellis, PP; Pfoff, DS; Riegel, M | 1 |
| Dang, H; Flescher, E; Fossum, D; Ledbetter, JA; Ogawa, N; Talal, N; Vela-Roch, N | 1 |
| Healy, CM; Thornhill, MH | 1 |
| Fry, LL | 1 |
| Foja, C; Giessler, C; Lautenschläger, C; Schäfer, K; Struck, HG | 1 |
| Ellis, PP; Riegel, M | 1 |
| Dada, VK; Gupta, SK; Sachdev, MS; Singh, K; Talwar, D | 1 |
| Lee, DA; Nguyen, KD | 1 |
| Flescher, E; Snyder, CA | 1 |
| Hessemer, V; Jacobi, A; Schmitt, K | 1 |
| Ward, DA | 1 |
| Andrioli, G; Bellavite, P; Lussignoli, S; Minuz, P; Ortolani, R; Vella, F | 1 |
| Brown, RM; Roberts, CW | 1 |
| Lu, KL; McDonnell, PJ; Sakamoto, T; Wee, WR | 1 |
| Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M | 1 |
| Ali, M; Shaikh, KA; Sharafatullah, T | 1 |
| Feron, VJ; Groene, EM; Horbach, GJ; Kappers, WA; Kleij, LA; Witkamp, RF; Zweers-Zeilmaker, WM | 1 |
| Diestelhorst, M; Konen, W; Mester, U; Schmidl, B | 1 |
| Martens, M | 1 |
| Roberts, CW | 1 |
| Diestelhorst, M; Konen, W; Mester, U; Raj, PS; Schmidl, B | 1 |
| Belmonte, C; Chen, X; Gallar, J | 1 |
| Andrioli, G; Bellavite, P; Benoni, G; Gaino, S; Lussignoli, S | 1 |
| Borgå, B; Borgå, O | 1 |
| Baek, SH; Chang, JH; Choi, SY; Lee, JH; Wee, WR | 1 |
| Gionfriddo, J; Krohne, SG; Morrison, EA | 1 |
| Giagoudakis, G; Markantonis, SL | 1 |
| Duman, S; Kasim, R; Koçak, A; Koçak, I; Nurözler, A; Unlü, N; Yalvaç, IS | 1 |
| Chiba, K; Goldstein, JA; Guengerich, FP; Inoue, K; Kawai, T; Ozawa, N; Shimada, T; Suzuki, Y; Yamazaki, H | 1 |
| Borodkin, MJ; McDonald, MB; Ocmand, A; Shoelson, B; Thompson, H; Wyse, TB | 1 |
| Kelly, JW; Klabunde, T; Oza, VB; Petrassi, HM; Raman, P; Sacchettini, JC | 1 |
| Aragona, P; Ferreri, G; Laganà, E; Spinella, R; Tripodi, G | 1 |
| Bell, K; Kulshrestha, MK; Thaller, VT | 1 |
| Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M; Takao, Y | 1 |
| Ichinose, H; Nakabayashi, K; Nakayama, M; Namiki, A; Satoh, O; Yamamoto, S | 1 |
| Cecchini, P; Pedio, M; Ravalico, G; Sanguinetti, G; Tognetto, D | 1 |
| Lozano, JJ; Pouplana, R; Ruiz, J | 1 |
| Egyed, A; Fedorocko, P; Hofer, M; Hoferová, Z; Hofmanová, J; Kozubík, A; Minksová, K; Soucek, K; Znojil, V | 1 |
| Kato, S; Kunikata, T; Miyazawa, T; Takeuchi, K; Tanaka, A | 1 |
| Jia, SB; Li, YP; Tang, LS | 1 |
| Bagheri, H; Lacroix, I; Lapeyre-Mestre, M; Montastruc, JL; Pathak, A | 1 |
| Hartnell, NR; Wilson, JP | 1 |
| Chono, S; Hosoya, O; Morimoto, K; Saso, Y; Seki, T; Wang, A; Yuan, D | 1 |
| Bégaud, B; Boisseau, M; Moore, N; Umar, A; Upur, H; Yusup, A | 1 |
| Acosta, MC; Belmonte, C; Berenguer-Ruiz, L; Gallar, J; García-Gálvez, A; Perea-Tortosa, D | 1 |
| Takahira, Y; Takeuchi, K; Tanaka, A; Yokota, A | 1 |
| Gorman, LA; Kumar, V; Rock, DA; Tracy, TS; Wahlstrom, JL; Warren, CJ | 1 |
| Jones, JP; Locuson, CW; Tracy, TS; Wienkers, LC | 1 |
| Dahlén, SE; Kumlin, M; Låstbom, L; Ryrfeldt, A; Selg, E | 1 |
| Kulmacz, RJ; Tsai, AL; Wu, G | 1 |
| Lee, JY; Sidhu, RS; Smith, WL; Yuan, C | 1 |
| Bortolozzo, S; Floreani, M; Moro, S; Nassi, A; Palatini, P; Pavanetto, M; Quintieri, L; Stragliotto, S | 1 |
| Khrone, SG; Rankin, AJ; Stiles, J | 1 |
| Agrawal, V; Miller, WL; Sandee, D; Subramanian, M; Tam, HK; Tracy, TS | 1 |
| Kato, T; Kinoshita, H; Miyoshi, H; Tanaka, H | 1 |
| Arimori, K; Ogata, K; Osaki, T; Ozaki, M; Setoguchi, N; Takamura, N; Tokunaga, J | 1 |
| Gjelstad, A; Pedersen-Bjergaard, S; Roldán-Pijuán, M | 1 |
| KuKanich, B; Lanuza, R; Meekins, JM; Rankin, AJ | 1 |
| Herrinton, LJ; Liu, L; Shorstein, NH; Waxman, MD | 1 |
| Eroğlu, CN; Kaplan, V | 1 |
| Amayem, A; Brown, MD; Ghandour, O; Harrison, N; Lang, E; Lawrenson, AL; Lawrenson, JG; McCormick, R; Quirke, M; Wakai, A; Walsh, CD; Wang, Y | 1 |
| Alshaikh, RA; El Maghraby, GM; Essa, EA | 1 |
| Domszy, R; Hu, N; Tammareddy, T; Torres-Luna, C; Wang, NS; Yang, A; Yang, J | 1 |
| Agrawal, NR; Briber, RM; Domszy, R; Fan, X; Hu, N; Koolivand, A; Torres-Luna, C; Wang, NS; Yang, A; Zhu, Y | 1 |
| Alalwani, A; Buhara, O; Tüzüm, MŞ | 1 |
| Glatz, Z; Michalcová, L; Nevídalová, H | 1 |
| Meekins, JM; Rankin, AJ; Roberts, JK; Roush, JK | 1 |
| Fuady, A; Matsumoto, H; Tomatsu, K; Yasuda, S | 1 |
| Gorenflo, M; Saur, P; van den Anker, JN; van Dyk, M; Welzel, T; Ziesenitz, VC | 1 |
| Aiello, F; Balzano, F; Nazzi, S; Picchi, C; Recchimurzo, A; Uccello-Barretta, G | 1 |
| Allbaugh, RA; Terhaar, HM; Van Vertloo, LR; Viall, AK | 1 |
9 review(s) available for diclofenac and flurbiprofen
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
Structural and functional basis of cyclooxygenase inhibition.
Topics: Animals; Cardiovascular System; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; History, 18th Century; History, 19th Century; History, 20th Century; History, 21st Century; History, Ancient; Humans; Kinetics; Models, Molecular; Protein Conformation; Risk Assessment | 2007 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Migraine and non-steroidal anti-inflammatory agents].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic Acid; Flurbiprofen; Humans; Metoclopramide; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Randomized Controlled Trials as Topic | 1992 |
The putative role of prostaglandins in cystoid macular edema.
Topics: Aqueous Humor; Cataract Extraction; Diclofenac; Fluorescein Angiography; Flurbiprofen; Humans; Indomethacin; Macular Edema; Prostaglandins | 1989 |
[Adjuvant therapy with nonsteroidal antiphlogistics in disease of the urogenital tract].
Topics: Anti-Inflammatory Agents; Aspirin; Diclofenac; Diflunisal; Escin; Flurbiprofen; Humans; Indomethacin; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Urologic Diseases | 1984 |
Preoperative and postoperative use of nonsteroidal antiinflammatory drugs in cataract surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; Flurbiprofen; Humans; Postoperative Care; Prednisolone; Premedication; Treatment Outcome | 1996 |
Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Corneal Injuries; Diclofenac; Flurbiprofen; Humans; Indomethacin; Ketorolac; Pain Measurement; Randomized Controlled Trials as Topic; Wound Healing | 2017 |
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Child; Chronic Disease; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Infant; Ketoprofen; Ketorolac; Meloxicam; Naproxen; Niflumic Acid; Pain | 2022 |
36 trial(s) available for diclofenac and flurbiprofen
| Article | Year |
|---|---|
[A clinical study of the efficacy and tolerance of nimesulide compared to flurbiprofen and sodium diclofenac in the prevention and treatment of postoperative pain and inflammatory symptoms in dentistry].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Tolerance; Female; Flurbiprofen; Humans; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Sulfonamides; Surgery, Oral | 1992 |
Double-blind randomized controlled trial of flurbiprofen-SR (ANSAID-SR) and diclofenac sodium-SR (Voltaren-SR) in the treatment of osteoarthritis.
Topics: Adolescent; Adult; Aged; Diclofenac; Double-Blind Method; Flurbiprofen; Humans; Middle Aged; Osteoarthritis; Osteoarthritis, Hip; Patient Compliance | 1992 |
The effect of indomethacin, diclofenac and flurbiprofen on the maintenance of mydriasis during extracapsular cataract extraction.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Diclofenac; Flurbiprofen; Humans; Indomethacin; Intraoperative Complications; Lens Capsule, Crystalline; Middle Aged; Miosis; Ophthalmic Solutions; Premedication; Pupil; Treatment Outcome | 1992 |
[Migraine and non-steroidal anti-inflammatory agents].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic Acid; Flurbiprofen; Humans; Metoclopramide; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Randomized Controlled Trials as Topic | 1992 |
Relationship between severity and clinical importance of symptoms in osteoarthritis.
Topics: Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Flurbiprofen; Humans; Male; Middle Aged; Osteoarthritis; Severity of Illness Index | 1991 |
Flurbiprofen versus diclofenac for the treatment of osteoarthritis of the knee.
Topics: Adult; Aged; Diclofenac; Double-Blind Method; Female; Flurbiprofen; Humans; Knee Joint; Male; Middle Aged; Osteoarthritis | 1990 |
A comparison of the analgesic efficacy of flurbiprofen, diclofenac, dihydrocodeine/paracetamol and placebo following oral surgery.
Topics: Adult; Analgesics; Clinical Trials as Topic; Diclofenac; Female; Flurbiprofen; Humans; Male; Pain, Postoperative; Tooth, Impacted | 1986 |
Controlled study on flurbiprofen and diclofenac in the treatment of rheumatic disorders.
Topics: Clinical Trials as Topic; Diclofenac; Female; Flurbiprofen; Humans; Male; Middle Aged; Phenylacetates; Propionates; Rheumatic Diseases | 1983 |
Treatment of osteoarthrosis of the spine: a comparison of flurbiprofen and diclofenac.
Topics: Adult; Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Administration Schedule; Female; Flurbiprofen; Humans; Male; Middle Aged; Osteoarthritis; Phenylacetates; Propionates; Random Allocation; Spinal Diseases | 1983 |
[Conservative treatment of arthrosis. Results of a comparative study with a new antiphlogistic agent, flurbiprofen (Froben) under the conditions of general practice].
Topics: Adult; Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Flurbiprofen; Humans; Joint Diseases; Male; Middle Aged; Propionates; Random Allocation | 1982 |
Intraocular diclofenac and flurbiprofen concentrations in human aqueous humor following topical application.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aqueous Humor; Biological Availability; Cataract Extraction; Chromatography, High Pressure Liquid; Diclofenac; Female; Flurbiprofen; Half-Life; Humans; Male; Middle Aged; Ophthalmic Solutions | 1994 |
Efficacy of diclofenac sodium solution in reducing discomfort after cataract surgery.
Topics: Administration, Topical; Carbachol; Cataract Extraction; Diclofenac; Flurbiprofen; Humans; Lenses, Intraocular; Miosis; Ophthalmic Solutions; Pain, Postoperative; Prospective Studies; Pupil; Suture Techniques | 1995 |
[Effect of diclofenac and flurbiprofen on the course of inflammation after cataract extraction].
Topics: Adult; Aged; Aged, 80 and over; Cataract Extraction; Diclofenac; Double-Blind Method; Endophthalmitis; Female; Flurbiprofen; Follow-Up Studies; Humans; Lenses, Intraocular; Male; Middle Aged; Ophthalmic Solutions; Postoperative Complications; Prospective Studies | 1994 |
Comparative efficacy of diclofenac and flurbiprofen for maintenance of pupillary dilatation during cataract surgery.
Topics: Administration, Topical; Cataract Extraction; Diclofenac; Double-Blind Method; Evaluation Studies as Topic; Flurbiprofen; Humans; Iris; Lenses, Intraocular; Ophthalmic Solutions; Prospective Studies; Pupil | 1994 |
[Anti-inflammatory effects and aqueous humor concentration of various nonsteroidal anti-inflammatory drugs in extracapsular cataract surgery].
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Blood-Retinal Barrier; Cataract Extraction; Chromatography, High Pressure Liquid; Diclofenac; Dose-Response Relationship, Drug; Drug Administration Schedule; Endophthalmitis; Female; Flurbiprofen; Humans; Indomethacin; Lenses, Intraocular; Male; Middle Aged; Ophthalmic Solutions; Postoperative Complications | 1996 |
Preoperative and postoperative use of nonsteroidal antiinflammatory drugs in cataract surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; Flurbiprofen; Humans; Postoperative Care; Prednisolone; Premedication; Treatment Outcome | 1996 |
Dose-response of flurbiprofen on postoperative pain and emesis after paediatric strabismus surgery.
Topics: Analgesics; Anesthesia, Inhalation; Anesthetics, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; Child, Preschool; Diclofenac; Dose-Response Relationship, Drug; Ethers; Flurbiprofen; Humans; Incidence; Injections, Intravenous; Methyl Ethers; Nausea; Nitrous Oxide; Pain Measurement; Pain, Postoperative; Placebos; Premedication; Prospective Studies; Sevoflurane; Single-Blind Method; Strabismus; Vomiting | 1997 |
Comparative study of diclofenac sodium and flurbiprofen in osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Flurbiprofen; Humans; Male; Osteoarthritis | 1996 |
[Laser flare measurement with 3 different nonsteroidal anti-inflammatory drugs after phacoemulsification with posterior chamber lens implantation].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Endophthalmitis; Female; Flurbiprofen; Humans; Indomethacin; Lenses, Intraocular; Male; Middle Aged; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prospective Studies | 1997 |
Efficacy and tolerability of a topical NSAID patch (local action transcutaneous flurbiprofen) and oral diclofenac in the treatment of soft-tissue rheumatism.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Confidence Intervals; Diclofenac; Drug Administration Schedule; Female; Flurbiprofen; Humans; Male; Middle Aged; Pain Measurement; Patient Satisfaction; Rheumatic Diseases; Treatment Outcome | 1997 |
Comparison of diclofenac sodium and flurbiprofen for inhibition of surgically induced miosis.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Flurbiprofen; Humans; Intraoperative Complications; Lenses, Intraocular; Male; Miosis; Ophthalmic Solutions; Phacoemulsification; Pupil; Treatment Outcome; Video Recording | 1996 |
Efficacy and tolerance of diclofenac sodium 0.1%, flurbiprofen 0.03%, and indomethacin 1.0% in controlling postoperative inflammation.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Endophthalmitis; Female; Flurbiprofen; Follow-Up Studies; Humans; Indomethacin; Lenses, Intraocular; Male; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prospective Studies; Treatment Outcome | 1996 |
Short-term effects of flurbiprofen and diclofenac on refractive outcome and corneal haze after photorefractive keratectomy.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Opacity; Diclofenac; Female; Fluorometholone; Flurbiprofen; Follow-Up Studies; Humans; Intraocular Pressure; Lasers, Excimer; Male; Myopia; Ophthalmic Solutions; Photorefractive Keratectomy; Prospective Studies; Refraction, Ocular; Treatment Outcome; Visual Acuity | 1997 |
Comparison of the anti-inflammatory effects of diclofenac and flurbiprofen eye drops after cataract extraction.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Cornea; Diclofenac; Double-Blind Method; Female; Flurbiprofen; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Middle Aged; Ophthalmic Solutions; Postoperative Complications; Prospective Studies; Safety; Uveitis, Anterior | 1998 |
Comparison of the effectiveness of 4 anti-inflammatory drops in relieving photophobia after pupil dilation.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Flurbiprofen; Follow-Up Studies; Humans; Ketorolac; Light; Mydriatics; Ophthalmic Solutions; Prednisolone; Prospective Studies; Pupil; Tolmetin; Treatment Outcome; Vision Disorders | 1999 |
The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity in normal subjects.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diclofenac; Double-Blind Method; Epithelium, Corneal; Female; Flurbiprofen; Humans; Indomethacin; Ketorolac; Male; Middle Aged; Paresthesia; Procaine | 2000 |
The effect of pre-operative topical flurbiprofen or diclofenac on pupil dilatation.
Topics: Adult; Analysis of Variance; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diclofenac; Double-Blind Method; Endophthalmitis; Flurbiprofen; Humans; Mydriatics; Postoperative Complications; Premedication; Pupil | 2000 |
Diclofenac and flurbiprofen with or without clonidine for postoperative analgesia in children undergoing elective ophthalmological surgery.
Topics: Administration, Oral; Administration, Rectal; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Clonidine; Diclofenac; Drug Therapy, Combination; Elective Surgical Procedures; Flurbiprofen; Humans; Injections, Intravenous; Ophthalmologic Surgical Procedures; Pain Measurement; Pain, Postoperative | 2000 |
Perioperative intravenous flurbiprofen reduces postoperative pain after abdominal hysterectomy.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cough; Diclofenac; Female; Flurbiprofen; Humans; Hysterectomy; Injections, Intravenous; Middle Aged; Pain Measurement; Pain, Postoperative | 2001 |
Comparative evaluation of corneal epithelial permeability after the use of diclofenac 0.1% and flurbiprofen 0.03% after phacoemulsification.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Diclofenac; Epithelial Cells; Female; Fluorescein; Fluorophotometry; Flurbiprofen; Humans; Lens Implantation, Intraocular; Male; Middle Aged; Ophthalmic Solutions; Permeability; Phacoemulsification; Prospective Studies | 2001 |
[Local instillation of 0.75% ropivacaine compared with intravenous fentanyl and flurbiprofen for postoperative analgesia following inguinal hernia repair in adults].
Topics: Aged; Aged, 80 and over; Amides; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Fentanyl; Flurbiprofen; Hernia, Inguinal; Humans; Intraoperative Care; Middle Aged; Pain, Postoperative; Phenylpropionates; Ropivacaine | 2012 |
Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac.
Topics: Administration, Ophthalmic; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Binding Sites; Cataract; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Serum Albumin | 2014 |
Evaluation of systemic absorption and renal effects of topical ophthalmic flurbiprofen and diclofenac in healthy cats.
Topics: Absorption, Physiological; Administration, Ophthalmic; Animals; Cats; Cyclooxygenase Inhibitors; Diclofenac; Eye; Female; Flurbiprofen; Male; Ophthalmic Solutions | 2016 |
Comparison of the Effects of Daily Single-Dose Use of Flurbiprofen, Diclofenac Sodium, and Tenoxicam on Postoperative Pain, Swelling, and Trismus: A Randomized Double-Blind Study.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Edema; Female; Flurbiprofen; Humans; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Piroxicam; Tooth, Impacted; Treatment Outcome; Trismus | 2016 |
Effects of topical instillation of 0.1% diclofenac sodium, 0.5% ketorolac tromethamine, and 0.03% flurbiprofen sodium on corneal sensitivity in ophthalmologically normal cats.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Diclofenac; Flurbiprofen; Ketorolac Tromethamine; Ophthalmic Solutions | 2021 |
Efficacy and safety of S-flurbiprofen plaster in knee osteoarthritis patients: A 2-week randomized controlled Phase III clinical trial compared to diclofenac gel.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Flurbiprofen; Humans; Osteoarthritis, Knee; Pain; Treatment Outcome | 2022 |
82 other study(ies) available for diclofenac and flurbiprofen
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship | 2000 |
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors | 2003 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Modulation of the fibrillogenesis inhibition properties of two transthyretin ligands by halogenation.
Topics: Diflunisal; Flufenamic Acid; Halogenation; Humans; Kinetics; Ligands; Models, Molecular; Prealbumin; Protein Multimerization; Protein Structure, Secondary; Structure-Activity Relationship | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Synthesis, pharmacological screening and in silico studies of new class of Diclofenac analogues as a promising anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Computer Simulation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Edema; Mice; Models, Molecular; Molecular Structure; Rats; Structure-Activity Relationship | 2014 |
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein.
Topics: Fatty Acid-Binding Proteins; Fluorescent Dyes; Humans; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spectrometry, Fluorescence | 2014 |
Failure of controlled clinical trial data to reach the literature.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diclofenac; Flurbiprofen; Humans; Ophthalmic Solutions; Peer Review; Periodicals as Topic; Suprofen | 1992 |
Pseudoallergic reactions to nonsteroidal anti-inflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Drug Eruptions; Female; Flurbiprofen; Humans; Naproxen | 1991 |
Aspirin-like drugs prime human T cells. Modulation of intracellular calcium concentrations.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Differentiation, T-Lymphocyte; Arachidonic Acid; Arachidonic Acids; Calcium; CD8 Antigens; Cell Division; Chromatography, High Pressure Liquid; Diclofenac; Dinoprostone; Drug Synergism; Female; Flow Cytometry; Flurbiprofen; Humans; Indomethacin; Interleukin-2; Lymphocyte Activation; Male; Middle Aged; Phytohemagglutinins; Radioimmunoassay; T-Lymphocytes | 1991 |
Topical nonsteroidal agents and corneal wound healing.
Topics: Administration, Topical; Analysis of Variance; Animals; Collagen; Cornea; Corneal Edema; Corneal Injuries; Corneal Stroma; Diclofenac; Double-Blind Method; Epithelium; Flurbiprofen; Hydroxyproline; Hyperemia; Iritis; Keratitis; Male; Prednisolone; Rabbits; Wound Healing | 1990 |
Assessment of diclofenac on herpes keratitis in rabbit eyes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Flurbiprofen; Keratitis, Dendritic; Prednisolone; Rabbits; Simplexvirus; Tears; Time Factors | 1989 |
Reduction of urinary protein and prostaglandin E2 excretion in the nephrotic syndrome by non-steroidal anti-inflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Diclofenac; Dinoprostone; Flurbiprofen; Glomerular Filtration Rate; Humans; Indomethacin; Male; Middle Aged; Nephrotic Syndrome; Prostaglandins E; Proteinuria; Renin; Sulindac | 1986 |
Adrenocorticotropin and beta-endorphin release from rat adenohypophysis in vitro: inhibition by prostaglandin E2 formed locally in response to vasopressin and corticotropin-releasing factor.
Topics: 1-Methyl-3-isobutylxanthine; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; beta-Endorphin; Corticotropin-Releasing Hormone; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Endorphins; Flurbiprofen; Indomethacin; Male; Pituitary Gland, Anterior; Potassium; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains | 1984 |
Topical flurbiprofen and diclofenac suppress blood-aqueous barrier breakdown in cataract surgery: a fluorophotometric study.
Topics: Administration, Topical; Aged; Capillary Permeability; Cataract Extraction; Diclofenac; Female; Flurbiprofen; Humans; Male; Middle Aged; Phenylacetates; Postoperative Complications; Propionates | 1983 |
[Inhibitory action of non-steroidal anti-flammatory drugs on prostaglandin synthesis and release (author's transl)].
Topics: Acetates; Animals; Anti-Inflammatory Agents; Aspirin; Depression, Chemical; Diclofenac; Flurbiprofen; Indomethacin; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Synovial Membrane; Synovitis; Thiazoles | 1980 |
Potential anticonvulsive properties of endogenous prostaglandins formed in mouse brain.
Topics: Animals; Brain; Diclofenac; Electroshock; Flurbiprofen; Indomethacin; Kinetics; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1982 |
A comparison of the effects of non-steroidal compounds on the disruption of the blood-aqueous barrier.
Topics: Animals; Anti-Inflammatory Agents; Aqueous Humor; Diclofenac; Eye; Eye Proteins; Flurbiprofen; Hydrogen-Ion Concentration; Indomethacin; Rabbits | 1982 |
Corneal wound healing strength with topical antiinflammatory drugs.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Diclofenac; Flurbiprofen; Ophthalmic Solutions; Prednisolone; Rabbits; Surgical Wound Dehiscence; Suture Techniques; Wound Healing | 1995 |
Alterations in the electroretinogram of newborn piglets by propionic acid-derivative nonsteroidal antiinflammatory drugs but not by indomethacin and diclofenac.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electroretinography; Flurbiprofen; Ibuprofen; Indomethacin; Naproxen; Photoreceptor Cells; Propionates; Prostaglandins; Retina; Swine | 1995 |
Induction of transcription factors in human T lymphocytes by aspirin-like drugs.
Topics: Adult; Base Sequence; Benzoquinones; Calcium; Cell Nucleus; Diclofenac; DNA-Binding Proteins; Female; Flurbiprofen; Gene Expression Regulation; Humans; Ibuprofen; Interleukin-2; Isoenzymes; Lactams, Macrocyclic; Lymphocyte Activation; Male; Middle Aged; Molecular Sequence Data; Muromonab-CD3; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Quinones; Rifabutin; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Type C Phospholipases | 1995 |
An association between recurrent oro-genital ulceration and non-steroidal anti-inflammatory drugs.
Topics: Diclofenac; Drug Hypersensitivity; Female; Flurbiprofen; Genital Diseases, Female; Humans; Middle Aged; Recurrence; Stomatitis, Aphthous; Ulcer | 1995 |
High-performance liquid chromatographic assay for antiinflammatory agents diclofenac and flurbiprofen in ocular fluids.
Topics: Animals; Aqueous Humor; Cataract Extraction; Chromatography, High Pressure Liquid; Diclofenac; Flurbiprofen; Humans; Rabbits; Sensitivity and Specificity | 1994 |
In vitro evaluation of antiproliferative potential of topical cyclooxygenase inhibitors in human Tenon's fibroblasts.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Connective Tissue; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Eye; Fibroblasts; Flurbiprofen; Humans; Mitosis; Piroxicam; Suprofen | 1993 |
Aspirin-like drugs can protect human T lymphocytes against benzoquinone cytotoxicity: evidence for a NAD(P)H:quinone reductase-dependent mechanism.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Cell Death; Cell Line; Diclofenac; Dicumarol; Dose-Response Relationship, Drug; Flurbiprofen; Humans; NAD(P)H Dehydrogenase (Quinone); T-Lymphocytes; Transcription Factor AP-1 | 1995 |
Comparative efficacy of topically applied flurbiprofen, diclofenac, tolmetin, and suprofen for the treatment of experimentally induced blood-aqueous barrier disruption in dogs.
Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Blood-Aqueous Barrier; Diclofenac; Dogs; Eye; Fluorescein; Fluoresceins; Fluorophotometry; Flurbiprofen; Ocular Physiological Phenomena; Ophthalmic Solutions; Random Allocation; Suprofen; Tolmetin | 1996 |
Dual effects of diclofenac on human platelet adhesion in vitro.
Topics: Adenosine Diphosphate; Diclofenac; Dose-Response Relationship, Drug; Flow Cytometry; Flurbiprofen; Humans; In Vitro Techniques; P-Selectin; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombin; Up-Regulation | 1996 |
Comparison of in vitro antiproliferative effects of steroids and nonsteroidal antiinflammatory drugs on human keratocytes.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cells, Cultured; Child; Cornea; Dexamethasone; Diclofenac; Flurbiprofen; Humans; Microscopy, Phase-Contrast; Osmolar Concentration | 1996 |
Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cell Line; Cricetinae; Cricetulus; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Diclofenac; Drug Interactions; Enzyme Inhibitors; Flurbiprofen; Gene Expression; Humans; Hydroxylation; Ketoprofen; Lung; Methylation; Mixed Function Oxygenases; Phenylbutazone; Sulfaphenazole; Tolbutamide; Transfection | 1996 |
Reduction by antiinflammatory drugs of the response of corneal sensory nerve fibers to chemical irritation.
Topics: Acetic Acid; Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Carbon Dioxide; Cats; Cornea; Cyclooxygenase Inhibitors; Diclofenac; Diltiazem; Electrophysiology; Female; Flurbiprofen; Indomethacin; Male; Nerve Fibers; Nociceptors; Pain; Trigeminal Nerve | 1997 |
Study on paradoxical effects of NSAIDs on platelet activation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 12-Lipoxygenase; Aristolochic Acids; Calcium; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flurbiprofen; Humans; In Vitro Techniques; Inflammation; Lipoxygenase Inhibitors; Masoprocol; Nitric Oxide; Phenanthrenes; Phospholipases A; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation | 1997 |
Serum protein binding of nonsteroidal antiinflammatory drugs: a comparative study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chromatography, High Pressure Liquid; Diclofenac; Female; Fenoprofen; Flurbiprofen; Humans; Ketoprofen; Male; Middle Aged; Naproxen; Protein Binding; Tolmetin | 1997 |
Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs.
Topics: Administration, Topical; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Aqueous Humor; Diclofenac; Dogs; Flurbiprofen; Intraocular Pressure; Miosis; Ocular Hypotension; Pilocarpine; Prednisolone; Propoxycaine; Suprofen; Time Factors | 1998 |
An alternative high-performance liquid chromatographic method for the determination of diclofenac and flurbiprofen in plasma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Artifacts; Chromatography, High Pressure Liquid; Diclofenac; Flurbiprofen; Humans; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1998 |
Comparative studies on the catalytic roles of cytochrome P450 2C9 and its Cys- and Leu-variants in the oxidation of warfarin, flurbiprofen, and diclofenac by human liver microsomes.
Topics: Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Catalysis; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Diclofenac; DNA; Flurbiprofen; Heterozygote; Humans; Hydroxylation; Oxidation-Reduction; Polymorphism, Genetic; RNA; Stereoisomerism; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Warfarin | 1998 |
Rational design of potent human transthyretin amyloid disease inhibitors.
Topics: Amino Acid Sequence; Amyloid Neuropathies; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Binding Sites; Cardiomyopathies; Crystallography, X-Ray; Dicarboxylic Acids; Diclofenac; Drug Design; Flurbiprofen; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; ortho-Aminobenzoates; Oxazines; Prealbumin; Protein Structure, Quaternary; Resveratrol; Stilbenes; Structure-Activity Relationship; Thermodynamics | 2000 |
Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Energy Transfer; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Ketoprofen; Meclofenamic Acid; Mefenamic Acid; Membrane Proteins; Models, Molecular; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2002 |
The effect of nonsteroidal antiinflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Cycle; Cell Division; Diclofenac; Fibrosarcoma; Flurbiprofen; Ibuprofen; In Vitro Techniques; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Survival Rate; Tumor Cells, Cultured | 2002 |
Pathogenic importance of intestinal hypermotility in NSAID-induced small intestinal damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dinoprostone; Flurbiprofen; Gastrointestinal Motility; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Naproxen; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Sprague-Dawley | 2002 |
[Diclofenac sodium or pred forte in the topical treatment of the fribrinous membrane after intraocular lens implantation in rabbits].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Synergism; Drug Therapy, Combination; Exudates and Transudates; Female; Fibrin; Flurbiprofen; Lens Implantation, Intraocular; Male; Ophthalmic Solutions; Postoperative Complications; Rabbits | 2003 |
Nonsteroidal anti-inflammatory drug-induced liver injury: a case-control study in primary care.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cholestasis; Diclofenac; Drug Therapy, Combination; Female; Flurbiprofen; Hepatocytes; Humans; Ibuprofen; Ketoprofen; Liver; Male; Meloxicam; Middle Aged; Niflumic Acid; Primary Health Care; Salicylates; Sex Distribution; Statistics, Nonparametric; Thiazines; Thiazoles; Time Factors | 2004 |
Replication of the Weber effect using postmarketing adverse event reports voluntarily submitted to the United States Food and Drug Administration.
Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Diflunisal; Epidemiologic Measurements; Flurbiprofen; Humans; Incidence; Piroxicam; Retrospective Studies; Sulindac; Time Factors; United Kingdom; United States; United States Food and Drug Administration | 2004 |
Effect of camellia oil on the permeation of flurbiprofen and diclofenac sodium through rat and pig skin.
Topics: Animals; Camellia; Cosmetics; Diclofenac; Flurbiprofen; In Vitro Techniques; Male; Permeability; Plant Oils; Rats; Rats, Wistar; Skin Absorption; Swine; Swine, Miniature | 2004 |
Interactions between aspirin and COX-2 inhibitors or NSAIDs in a rat thrombosis model.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Flurbiprofen; Ibuprofen; Isoenzymes; Lactones; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulfones; Thrombosis | 2004 |
Changes in mechanical, chemical, and thermal sensitivity of the cornea after topical application of nonsteroidal anti-inflammatory drugs.
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Carbon Dioxide; Cornea; Diclofenac; Female; Flurbiprofen; Hot Temperature; Humans; Male; Ophthalmic Nerve; Ophthalmic Solutions; Sensation; Stress, Mechanical | 2005 |
Factors involved in upregulation of inducible nitric oxide synthase in rat small intestine following administration of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Disease Models, Animal; Enterobacteriaceae; Flurbiprofen; Gastrointestinal Motility; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Lactones; Male; Naproxen; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfones; Time Factors; Up-Regulation | 2006 |
CYP2C9 inhibition: impact of probe selection and pharmacogenetics on in vitro inhibition profiles.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Diclofenac; Enzyme Inhibitors; Flurbiprofen; Genotype; In Vitro Techniques; Pharmacogenetics; Phenytoin; Piroxicam; Tolbutamide; Warfarin | 2006 |
CYP2C9 protein interactions with cytochrome b(5): effects on the coupling of catalysis.
Topics: Allosteric Regulation; Animals; Aryl Hydrocarbon Hydroxylases; Catalysis; Cytochrome P-450 CYP2C9; Cytochromes b5; Diclofenac; Flurbiprofen; Heme; Humans; Hydrogen Peroxide; Kinetics; Models, Biological; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Conformation; Rats; Recombinant Proteins; Warfarin; Water | 2007 |
Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung.
Topics: Animals; Bronchoconstriction; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Flurbiprofen; Guinea Pigs; Humans; Leukotrienes; Lung; Male; Ovalbumin; Piperazines; Prostaglandins; Pyrazoles; Sulfonamides; Thiazoles; Thromboxane A2; Thromboxane B2 | 2008 |
Cyclooxygenase competitive inhibitors alter tyrosyl radical dynamics in prostaglandin H synthase-2.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; Catalysis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Enzyme Activation; Enzyme Stability; Flurbiprofen; Free Radicals; Humans; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thermodynamics; Tyrosine | 2009 |
Comparison of cyclooxygenase-1 crystal structures: cross-talk between monomers comprising cyclooxygenase-1 homodimers.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catalytic Domain; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Diclofenac; Flurbiprofen; Ligands; Models, Molecular; Protein Binding; Protein Conformation; Protein Multimerization; Sheep; Sulfonamides | 2010 |
Flavonoids diosmetin and hesperetin are potent inhibitors of cytochrome P450 2C9-mediated drug metabolism in vitro.
Topics: Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Biocatalysis; Cytochrome P-450 CYP2C9; Diclofenac; Female; Flavonoids; Flurbiprofen; Hesperidin; Humans; Hydroxylation; Male; Microsomes, Liver; Models, Molecular; NADP; Pharmaceutical Preparations; Recombinant Proteins; Thermodynamics | 2010 |
Evaluation of four drugs for inhibition of paracentesis-induced blood-aqueous humor barrier breakdown in cats.
Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents; Aqueous Humor; Blood-Aqueous Barrier; Cat Diseases; Cats; Diclofenac; Female; Flurbiprofen; Intraocular Pressure; Male; Ocular Hypertension; Paracentesis; Pregnadienetriols; Uveitis, Anterior | 2011 |
Effect of P450 oxidoreductase variants on the metabolism of model substrates mediated by CYP2C9.1, CYP2C9.2, and CYP2C9.3.
Topics: Aryl Hydrocarbon Hydroxylases; Catalysis; Cytochrome P-450 CYP2C9; Diclofenac; Flurbiprofen; Humans; Kinetics; NADPH-Ferrihemoprotein Reductase; Polymorphism, Genetic; Recombinant Proteins; Tolbutamide | 2012 |
Parallel artificial liquid membrane extraction of acidic drugs from human plasma.
Topics: Calibration; Chromatography, High Pressure Liquid; Diclofenac; Equipment Design; Flurbiprofen; Gemfibrozil; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Liquid-Liquid Extraction; Membranes, Artificial; Pharmaceutical Preparations; Polypropylenes; Polyvinyls | 2015 |
Comparative Effectiveness of Three Prophylactic Strategies to Prevent Clinical Macular Edema after Phacoemulsification Surgery.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Therapy, Combination; Female; Flurbiprofen; Glucocorticoids; Humans; Injections, Intraocular; Ketorolac; Lens Implantation, Intraocular; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prednisolone; Retrospective Studies; Treatment Outcome; Triamcinolone Acetonide; Visual Acuity | 2015 |
Eutexia for enhanced dissolution rate and anti-inflammatory activity of nonsteroidal anti-inflammatory agents: Caffeine as a melting point modulator.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Carrageenan; Diclofenac; Drug Liberation; Edema; Flurbiprofen; Male; Meloxicam; Powder Diffraction; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Transition Temperature; X-Ray Diffraction | 2019 |
Extended delivery of non-steroidal anti-inflammatory drugs through contact lenses loaded with Vitamin E and cationic surfactants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Contact Lenses, Hydrophilic; Delayed-Action Preparations; Diclofenac; Drug Delivery Systems; Fatty Alcohols; Flurbiprofen; Ketorolac Tromethamine; Quaternary Ammonium Compounds; Surface-Active Agents; Vitamin E | 2019 |
Formation of Drug-Participating Catanionic Aggregates for Extended Delivery of Non-Steroidal Anti-Inflammatory Drugs from Contact Lenses.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cations; Contact Lenses; Diclofenac; Diffusion; Drug Delivery Systems; Drug Liberation; Fatty Alcohols; Flurbiprofen; Hydrophobic and Hydrophilic Interactions; Kinetics; Naproxen; Quaternary Ammonium Compounds; Surface-Active Agents; Viscosity | 2019 |
Oral Health-Related Quality of Life and the Use of Oral and Topical Nonsteroidal Anti-Inflammatory Drugs for Pericoronitis.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Benzydamine; Diclofenac; Female; Flurbiprofen; Humans; Male; Oral Health; Pericoronitis; Quality of Life; Young Adult | 2019 |
Applicability of capillary electrophoresis-frontal analysis for displacement studies: Effect of several drugs on l-tryptophan and lidocaine binding to human serum albumin.
Topics: Binding Sites; Chlorpropamide; Diclofenac; Electrophoresis, Capillary; Flurbiprofen; Humans; Ibuprofen; Lidocaine; Phenylbutazone; Serum Albumin, Human; Tolbutamide; Tryptophan | 2020 |
NMR Investigation of the Interaction of Three Non-Steroidal Anti-Inflammatory Drugs with Human Serum Albumin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Diclofenac; Flurbiprofen; Humans; Ketorolac; Magnetic Resonance Spectroscopy; Protons; Serum Albumin, Human | 2022 |
Retrospective evaluation of the incidence of gastrointestinal bleeding in dogs receiving ophthalmic nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dog Diseases; Dogs; Flurbiprofen; Gastrointestinal Hemorrhage; Glucocorticoids; Incidence; Ketorolac; Prednisone; Retrospective Studies | 2023 |