diclofenac and fluoxetine

diclofenac has been researched along with fluoxetine in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (11.76)	29.6817
2010's	29 (85.29)	24.3611
2020's	1 (2.94)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Dansette, PM; Fontana, E; Poli, SM	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ	1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C	1
Bennis, K; Ducki, S; Lesage, F; Vivier, D	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
DeLorenzo, ME; Fleming, J	1
Baker, SJ; Boyce-Rustay, JM; Decker, MW; Honore, P; Kohnken, R; Simler, GH; Wensink, EJ; Zhong, C	1
Ford, AT; Guler, Y	1
Fernandes, D; Porte, C; Schnell, S	1
Bragg, LM; Dixon, G; Oakes, KD; Pawliszyn, J; Servos, MR; Wang, S	1
Coleman, HM; Khan, SJ; Le-Clech, P; Stuetz, RM; Trinh, T; van den Akker, B	1
Bainy, AC; Bebianno, MJ; Gonzalez-Rey, M; Mattos, JJ; Piazza, CE	1
Bergström, E; Boxall, AB; Carter, LJ; Dowle, A; Garman, CD; Ryan, J; Thomas-Oates, J	1
Ribalta, C; Solé, M	1
Budzinski, H; Choubert, JM; Coquery, M; Miège, C; Pomiès, M; Wisniewski, C	1
Boxall, AB; Gouin, T; Karlsson, MV; Marshall, S	1
Batley, GE; Hutchinson, TH; Kumar, A; Nidumolu, B	1
Boxall, ABA; Carter, LJ; Ryan, JJ	1
Castro, PML; Márquez Brazón, E; Moreira, IS; Piccirillo, C	1
Barbosa, J; Cabral, HN; Duarte, IA; Fonseca, VF; Freitas, A; Lemos, MFL; Novais, SC; Pouca, ASV; Rato, LD; Reis-Santos, P	1

Reviews

3 review(s) available for diclofenac and fluoxetine

Article	Year
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Current drug metabolism, 2005, Volume: 6, Issue:5 Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic	2005
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target? Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11 Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship	2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

31 other study(ies) available for diclofenac and fluoxetine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results	2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Glutathione; Pharmacology; Sulfur Radioisotopes	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells). Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4 Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles	2013
Individual and mixture effects of selected pharmaceuticals and personal care products on the marine phytoplankton species Dunaliella tertiolecta. Archives of environmental contamination and toxicology, 2008, Volume: 54, Issue:2 Topics: Carbamazepine; Chlorophyta; Clofibric Acid; Diclofenac; Drug Interactions; Fluoxetine; Household Products; Phytoplankton; Simvastatin; Triclosan; Water Pollutants, Chemical	2008
Comparison of mechanical allodynia and the affective component of inflammatory pain in rats. Neuropharmacology, 2010, Volume: 58, Issue:2 Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Celecoxib; Central Nervous System Agents; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Escape Reaction; Fluoxetine; Inflammation; Male; Motor Activity; Neuropsychological Tests; Pain; Pain Measurement; Physical Stimulation; Pyrazoles; Rats; Rats, Sprague-Dawley; Scopolamine; Sulfonamides; Thiophenes; Treatment Outcome	2010
Anti-depressants make amphipods see the light. Aquatic toxicology (Amsterdam, Netherlands), 2010, Sep-01, Volume: 99, Issue:3 Topics: Amphipoda; Animals; Antidepressive Agents; Behavior, Animal; Carbamazepine; Diclofenac; Fluoxetine; Male; Serotonin; Swimming; Water Pollutants, Chemical	2010
Can pharmaceuticals interfere with the synthesis of active androgens in male fish? An in vitro study. Marine pollution bulletin, 2011, Volume: 62, Issue:10 Topics: Androgens; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Biomarkers; Carps; Clofibrate; Clofibric Acid; Diclofenac; Fibric Acids; Fluoxetine; Gemfibrozil; Ibuprofen; Male; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase; Testis; Water Pollutants, Chemical	2011
Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish. Chemosphere, 2011, Volume: 85, Issue:9 Topics: Animals; Atrazine; Benzhydryl Compounds; Carbamazepine; Diclofenac; Environmental Monitoring; Fishes; Fluoxetine; Gemfibrozil; Ibuprofen; Naproxen; Phenols; Solid Phase Extraction; Solid Phase Microextraction; Waste Disposal, Fluid; Water Pollutants, Chemical	2011
Removal of trace organic chemical contaminants by a membrane bioreactor. Water science and technology : a journal of the International Association on Water Pollution Research, 2012, Volume: 66, Issue:9 Topics: Amitriptyline; Bioreactors; Carbamazepine; Diazepam; Diclofenac; Fluoxetine; Gemfibrozil; Omeprazole; Organic Chemicals; Pharmaceutical Preparations; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Pollutants, Chemical	2012
Effects of active pharmaceutical ingredients mixtures in mussel Mytilus galloprovincialis. Aquatic toxicology (Amsterdam, Netherlands), 2014, Volume: 153 Topics: Animals; Biomarkers; Copper; Diclofenac; Enzyme Activation; Fluoxetine; Gene Expression Regulation, Enzymologic; Gills; Ibuprofen; Lipid Peroxidation; Mytilus; Oxidative Stress; Oxidoreductases; Water Pollutants, Chemical	2014
Fate and uptake of pharmaceuticals in soil-earthworm systems. Environmental science & technology, 2014, May-20, Volume: 48, Issue:10 Topics: Adsorption; Animals; Biodegradation, Environmental; Carbamazepine; Diclofenac; Fluoxetine; Lactones; Models, Biological; Oligochaeta; Orlistat; Pharmaceutical Preparations; Porosity; Quantitative Structure-Activity Relationship; Soil; Time Factors; Water	2014
In vitro interaction of emerging contaminants with the cytochrome p450 system of Mediterranean deep-sea fish. Environmental science & technology, 2014, Oct-21, Volume: 48, Issue:20 Topics: Animals; Benzopyrans; Cytochrome P-450 Enzyme System; Diclofenac; Female; Fish Proteins; Fishes; Fluoxetine; Gemfibrozil; Male; Mediterranean Sea; Phenols; Triclosan; Water Pollutants, Chemical; Xenobiotics	2014
Lab-scale experimental strategy for determining micropollutant partition coefficient and biodegradation constants in activated sludge. Environmental science and pollution research international, 2015, Volume: 22, Issue:6 Topics: Aerobiosis; Anaerobiosis; Atenolol; Biodegradation, Environmental; Carbon; Denitrification; Diclofenac; Fluoxetine; Ibuprofen; Nitrification; Sewage; Wastewater; Water Pollutants, Chemical	2015
Routes of uptake of diclofenac, fluoxetine, and triclosan into sediment-dwelling worms. Environmental toxicology and chemistry, 2016, Volume: 35, Issue:4 Topics: Animals; Anti-Infective Agents, Local; Biota; Biotransformation; Diclofenac; Fluoxetine; Geologic Sediments; Oligochaeta; Triclosan; Water; Water Pollutants, Chemical	2016
Derivation of water quality guidelines for priority pharmaceuticals. Environmental toxicology and chemistry, 2016, Volume: 35, Issue:7 Topics: Animals; Aquatic Organisms; Carbamazepine; Diclofenac; Fluoxetine; Fresh Water; Guidelines as Topic; Pharmaceutical Preparations; Propranolol; Toxicity Tests, Chronic; Water Pollutants, Chemical; Water Quality	2016
Effects of soil properties on the uptake of pharmaceuticals into earthworms. Environmental pollution (Barking, Essex : 1987), 2016, Volume: 213 Topics: Animals; Carbamazepine; Diclofenac; Fluoxetine; Hydrogen-Ion Concentration; Lactones; Oligochaeta; Orlistat; Pharmaceutical Preparations; Soil; Soil Pollutants; Water	2016
Photodegradation of pharmaceutical persistent pollutants using hydroxyapatite-based materials. Journal of environmental management, 2016, Nov-01, Volume: 182 Topics: Acetonitriles; Biocompatible Materials; Catalysis; Crystallization; Diclofenac; Durapatite; Environmental Monitoring; Environmental Restoration and Remediation; Fluoxetine; Oxygen; Pharmaceutical Preparations; Photolysis; Powders; Titanium; Ultraviolet Rays; Wastewater; Water Pollutants, Chemical; Water Purification	2016
Depressed, hypertense and sore: Long-term effects of fluoxetine, propranolol and diclofenac exposure in a top predator fish. The Science of the total environment, 2020, Apr-10, Volume: 712 Topics: Animals; Biomarkers; Diclofenac; Fishes; Fluoxetine; Oxidative Stress; Propranolol; Water Pollutants, Chemical	2020