diclofenac and fluorouracil

diclofenac has been researched along with fluorouracil in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.56)	18.7374
1990's	0 (0.00)	18.2507
2000's	22 (34.38)	29.6817
2010's	34 (53.13)	24.3611
2020's	7 (10.94)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bernardino, AMR; Boechat, N; Dos Santos, MS; Faria, JV; Miguita, AGC; Vegi, PF	1
Hobara, N; Watanabe, A	1
Alam, M; Goldberg, LH; Silapunt, S	1
Ghafourian, T; Hamishekar, H; Nokhodchi, A; Zandasrar, P	1
Fein, H; McGillis, ST	1
Jorizzo, JL	1
Morhenn, VB; Piacquadio, DJ; Smith, SR	1
Berman, B; Ramirez, CC; Villa, AM	1
Berman, B; Bienstock, L; Kuritzky, L; Mayeaux, EJ; Tyring, SK	1
Chia, A; Lim, A; Moreno, G; Shumack, S	1
Bedwell, SA; Downs, MR; McIntyre, WJ	1
Gold, MH	1
Weinberg, JM	1
Drakulić, BJ; Erić, S; Juranić, IO; Zloh, M	1
Ulrich, C	1
Xu, W; Yang, Y	3
Dinotta, F; Lacarrubba, F; Massimino, D; Micali, G; Nasca, MR	1
Muhn, C; Rosen, N; Shoimer, I	1
Adam, F; Fenske, NA; Spencer, J	1
Goldenberg, G; Skupsky, H; Skupsky, J	1
Clark, AR; Huang, WW	1
Kerl, H; Stockfleth, E; Willers, C; Zwingers, T	1
Chen, CL; Desai, A; Desai, T; Kirby, W	1
Jadotte, YT; Schwartz, RA	1
Esmann, S; Jemec, GB	1
Gupta, AK; Paquet, M	1
Cockerell, CJ; Samrao, A	1
Boscornea, C; Cursaru, B; Stanescu, PO; Stoleriu, S; Teodorescu, M	1
Calzavara Pinton, P; Catricalà, C; Neri, L; Pellacani, G; Peris, K; Peserico, A; Pimpinelli, N	1
Burcharth, J; Pommergaard, HC; Raskov, H; Rosenberg, J	1
Kemmett, D; Nasr, R; Smethurst, H; Thybo, S; Tolley, K	1
Isoherranen, K; Koskenmies, S; Overmark, M; Pitkänen, S; Saksela, O; Ylitalo, L	1
Erdmann, R; Jacobs, A; Nast, A; Rosumeck, S; Sporbeck, B; Werner, RN	1
Gilaberte, Y; González, S; Gracia-Cazaña, T	1
Borkowska, JK; Czuwara, J; Damps, T; Konop, M; Kowalkowski, T; Laskowska, AK; Misicka, A; Prokopowicz, M; Puszko, AK; Różycki, K; Rudnicka, L; Sosnowski, P	1
da Motta, VRV; de Oliveira, ECV; Galadari, H; Ilha, CSO; Leonardi, GR; Magalhães, RF; Pantoja, PC	1
Costa, C; Fabbrocini, G; Greco, V; Mazzella, C; Russo, D; Savastano, R; Scalvenzi, M; Staibano, S	1
Calzavara-Pinton, P; Hamon, P; Tanova, N	1
Council, ML; Nemer, KM	1
Herms, F	1
Bayraktar, H; Demir, D; Duman, BO; Guven, M; Halbutogulları, ZSU; Kara, A; Kara, RO; SinanYilmaz, M; Yazır, Y	1
Cornacchia, L; Lai, M; Longo, C; Pampena, R; Pellacani, G; Peris, K	1
Collins, A; Doerfler, L; Savas, J	1
Conforti, C; Corneli, P; di Meo, N; Dianzani, C; Farinazzo, E; Giuffrida, R; Magaton Rizzi, G; Moret, A; Zalaudek, I	1
Baker, C; MacMahon, B; Sinclair, R; Spelman, L; Supranowicz, M	1
Asgari, MM; Bennett, DD; Connolly, SM; Dellavalle, RP; Eisen, DB; Frazer-Green, L; Freeman, EE; Goldenberg, G; Leffell, DJ; Malik, S; Peschin, S; Schlesinger, TE; Sligh, JE; Wu, PA	1
Calzavara-Pinton, I; Calzavara-Pinton, P; Rossi, M; Rovati, C	1
Arcuri, D; Iannattone, L; Lagacé, F; Lefrançois, P; Litvinov, IV; Netchiporouk, E; Ramchatesingh, B	1
Andersen, F; Bjerring, P; Haedersdal, M; Lerche, CM; Pihl, C	1

Reviews

29 review(s) available for diclofenac and fluorouracil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Recently reported biological activities of pyrazole compounds. Bioorganic & medicinal chemistry, 2017, 11-01, Volume: 25, Issue:21 Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Pyrazoles	2017
Topical and light-based treatments for actinic keratoses. Seminars in cutaneous medicine and surgery, 2003, Volume: 22, Issue:3 Topics: Adjuvants, Immunologic; Administration, Topical; Aminolevulinic Acid; Aminoquinolines; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclooxygenase Inhibitors; Diclofenac; Fluorouracil; Humans; Hyaluronic Acid; Imiquimod; Keratosis; Photochemotherapy; Photosensitivity Disorders; Photosensitizing Agents; Precancerous Conditions; Retinoids; Skin Neoplasms; Vitamin A	2003
Topical treatment strategies for non-melanoma skin cancer and precursor lesions. Seminars in cutaneous medicine and surgery, 2004, Volume: 23, Issue:3 Topics: Administration, Topical; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinoma, Basal Cell; Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis; Photochemotherapy; Precancerous Conditions; Skin Neoplasms; Sunlight	2004
Current and novel treatment options for actinic keratosis. Journal of cutaneous medicine and surgery, 2004, Volume: 8 Suppl 3 Topics: Aminolevulinic Acid; Aminoquinolines; Cryotherapy; Diclofenac; Fluorouracil; Gels; Humans; Imiquimod; Immunosuppressive Agents; Keratosis; Photochemotherapy; Photosensitizing Agents; Treatment Outcome	2004
Mechanisms of action of new treatment modalities for actinic keratosis. Journal of drugs in dermatology : JDD, 2006, Volume: 5, Issue:2 Topics: Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Antineoplastic Agents; Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis; Photochemotherapy; Randomized Controlled Trials as Topic; Teratogens	2006
Actinic keratoses: sequelae and treatments. Recommendations from a consensus panel. The Journal of family practice, 2006, Volume: 55, Issue:5 Topics: Administration, Cutaneous; Aminoquinolines; Antineoplastic Agents; Carcinoma, Squamous Cell; Consensus Development Conferences as Topic; Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis; Photosensitivity Disorders; Practice Guidelines as Topic; Risk Factors; Skin Neoplasms; Ultraviolet Rays	2006
Actinic keratoses. Australian family physician, 2007, Volume: 36, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Australia; Cryotherapy; Diclofenac; Fluorouracil; Humans; Photosensitivity Disorders; Skin Neoplasms; Sunlight	2007
Treatment options for actinic keratoses. American family physician, 2007, Sep-01, Volume: 76, Issue:5 Topics: Administration, Topical; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Chemexfoliation; Cryosurgery; Curettage; Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis; Photochemotherapy; Prevalence; Skin Neoplasms	2007
Topical therapy for actinic keratoses: current and evolving therapies. Reviews on recent clinical trials, 2006, Volume: 1, Issue:1 Topics: Administration, Cutaneous; Administration, Topical; Aminoquinolines; Antineoplastic Agents; Carcinoma in Situ; Colchicine; Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis; Neoplasms, Squamous Cell; Retinoids; Skin Neoplasms; Treatment Outcome; Ultraviolet Rays	2006
Topical treatment of field cancerization. Cancer treatment and research, 2009, Volume: 146 Topics: Aminoquinolines; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Diclofenac; Fluorouracil; Humans; Imiquimod; Immunosuppression Therapy; Immunosuppressive Agents; Keratosis, Actinic; Organ Transplantation; Photochemotherapy; Recurrence; Skin Neoplasms; Tissue Distribution	2009
Treating skin cancer with topical cream. Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:9 Topics: Administration, Topical; Aminoquinolines; Antineoplastic Agents; Carcinoma, Basal Cell; Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Retinoids; Skin Neoplasms	2010
Actinic keratoses: past, present and future. Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:5 Suppl OD Topics: Adjuvants, Immunologic; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Squamous Cell; Cryosurgery; Diclofenac; Fluorouracil; Humans; Imiquimod; Immunosuppressive Agents; Keratosis, Actinic; Photochemotherapy; Precancerous Conditions; Skin Neoplasms	2010
Disseminated superficial actinic porokeratosis: a treatment review. The Journal of dermatological treatment, 2012, Volume: 23, Issue:1 Topics: Aminolevulinic Acid; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Cholecalciferol; Diclofenac; Fluorouracil; Humans; Imiquimod; Immunosuppressive Agents; Interferon Inducers; Laser Therapy; Photochemotherapy; Photosensitizing Agents; Porokeratosis; Retinoids; Vitamins	2012
Basic pharmacology of topical imiquimod, 5-fluorouracil, and diclofenac for the dermatologic surgeon. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2012, Volume: 38, Issue:1 Topics: Administration, Topical; Aminoquinolines; Antineoplastic Agents; Diclofenac; Fluorouracil; Humans; Imiquimod; Skin Neoplasms	2012
Network meta-analysis of the outcome 'participant complete clearance' in nonimmunosuppressed participants of eight interventions for actinic keratosis: a follow-up on a Cochrane review. The British journal of dermatology, 2013, Volume: 169, Issue:2 Topics: Adjuvants, Immunologic; Aged; Aminolevulinic Acid; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Cryotherapy; Diclofenac; Diterpenes; Drug Combinations; Female; Fluorouracil; Follow-Up Studies; Humans; Hyaluronic Acid; Imiquimod; Immunocompetence; Immunosuppressive Agents; Keratosis, Actinic; Male; Middle Aged; Photochemotherapy; Photosensitizing Agents; Randomized Controlled Trials as Topic; Treatment Outcome	2013
Pharmacotherapeutic management of actinic keratosis: focus on newer topical agents. American journal of clinical dermatology, 2013, Volume: 14, Issue:4 Topics: Administration, Topical; Aminoquinolines; Cryotherapy; Diclofenac; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Imiquimod; Keratosis, Actinic; Male; Photochemotherapy; Precancerous Conditions; Severity of Illness Index; Treatment Outcome	2013
[Diagnosis and treatment of actinic keratosis]. Duodecim; laaketieteellinen aikakauskirja, 2015, Volume: 131, Issue:9 Topics: Administration, Topical; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cryotherapy; Diclofenac; Diterpenes; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Laser Therapy; Photochemotherapy; Precancerous Conditions; Primary Health Care	2015
Resistance of Nonmelanoma Skin Cancer to Nonsurgical Treatments. Part I: Topical Treatments. Actas dermo-sifiliograficas, 2016, Volume: 107, Issue:9 Topics: Adjuvants, Immunologic; Administration, Cutaneous; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Presenting Cells; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma; Clinical Trials as Topic; Dermatologic Agents; Diclofenac; Diterpenes; Drug Resistance, Neoplasm; Fluorouracil; Humans; Imiquimod; Meta-Analysis as Topic; Neoplasm Proteins; Neoplastic Stem Cells; Skin Neoplasms	2016
Actinic keratosis - review for clinical practice. International journal of dermatology, 2019, Volume: 58, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cryotherapy; Diclofenac; Diterpenes; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Photochemotherapy; Retinoids	2019
Topical and Systemic Modalities for Chemoprevention of Nonmelanoma Skin Cancer. Dermatologic clinics, 2019, Volume: 37, Issue:3 Topics: Administration, Cutaneous; Administration, Oral; Antineoplastic Agents; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Chemoprevention; Cyclooxygenase Inhibitors; Diclofenac; Diterpenes; Fluorouracil; Humans; Imiquimod; Niacinamide; Photochemotherapy; Retinoids; Skin Neoplasms	2019
Treatments of actinic cheilitis: A systematic review of the literature. Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:3 Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cheilitis; Combined Modality Therapy; Dermabrasion; Diclofenac; Disease Progression; Fluorouracil; Humans; Imiquimod; Laser Therapy; Lip Neoplasms; Photochemotherapy; Precancerous Conditions; Treatment Outcome	2020
Nonsurgical Treatments for Nonmelanoma Skin Cancer. Dermatologic clinics, 2019, Volume: 37, Issue:4 Topics: Administration, Cutaneous; Anilides; Antineoplastic Agents; Antineoplastic Agents, Immunological; Biphenyl Compounds; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cryosurgery; Cyclooxygenase Inhibitors; Diclofenac; Diterpenes; Fluorouracil; Humans; Imiquimod; Photochemotherapy; Programmed Cell Death 1 Receptor; Pyridines; Radiotherapy; Skin Neoplasms; Watchful Waiting	2019
Current therapies for actinic keratosis. International journal of dermatology, 2020, Volume: 59, Issue:6 Topics: Aftercare; Carcinoma, Squamous Cell; Chemexfoliation; Cryotherapy; Curettage; Dermoscopy; Diclofenac; Disease Progression; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Laser Therapy; Photochemotherapy; Practice Guidelines as Topic; Protective Clothing; Skin; Skin Neoplasms; Sunlight; Sunscreening Agents	2020
A review of actinic keratosis, skin field cancerisation and the efficacy of topical therapies. The Australasian journal of dermatology, 2021, Volume: 62, Issue:2 Topics: Antineoplastic Agents; Diclofenac; Disease Progression; Diterpenes; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Photochemotherapy; Recurrence; Skin Neoplasms	2021
Guidelines of care for the management of actinic keratosis. Journal of the American Academy of Dermatology, 2021, Volume: 85, Issue:4 Topics: Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Photochemotherapy	2021
Topical Pharmacotherapy for Actinic Keratoses in Older Adults. Drugs & aging, 2022, Volume: 39, Issue:2 Topics: Aged; Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Treatment Outcome	2022
Pharmacological Agents Used in the Prevention and Treatment of Actinic Keratosis: A Review. International journal of molecular sciences, 2023, Mar-05, Volume: 24, Issue:5 Topics: Aminolevulinic Acid; Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Photochemotherapy; Photosensitizing Agents; Treatment Outcome	2023
Improving the efficacy of photodynamic therapy for actinic keratosis: A comprehensive review of pharmacological pretreatment strategies. Photodiagnosis and photodynamic therapy, 2023, Volume: 43 Topics: Aminolevulinic Acid; Diclofenac; Fluorouracil; Humans; Keratosis, Actinic; Photochemotherapy; Photosensitizing Agents; Retinoids; Salicylic Acid; Treatment Outcome; Urea; Vitamin D	2023

Trials

2 trial(s) available for diclofenac and fluorouracil

Article	Year
Bilateral comparison of the efficacy and tolerability of 3% diclofenac sodium gel and 5% 5-fluorouracil cream in the treatment of actinic keratoses of the face and scalp. Journal of drugs in dermatology : JDD, 2006, Volume: 5, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Diclofenac; Facial Dermatoses; Female; Fluorouracil; Gels; Humans; Keratosis; Male; Middle Aged; Patient Satisfaction; Scalp Dermatoses; Severity of Illness Index	2006
Low-dose 5-fluorouracil in combination with salicylic acid as a new lesion-directed option to treat topically actinic keratoses: histological and clinical study results. The British journal of dermatology, 2011, Volume: 165, Issue:5 Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Hyaluronic Acid; Keratolytic Agents; Keratosis, Actinic; Male; Middle Aged; Salicylic Acid; Treatment Outcome	2011

Article

Year

Bilateral comparison of the efficacy and tolerability of 3% diclofenac sodium gel and 5% 5-fluorouracil cream in the treatment of actinic keratoses of the face and scalp.

Journal of drugs in dermatology : JDD, 2006, Volume: 5, Issue:2

Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Diclofenac; Facial Dermatoses; Female; Fluorouracil; Gels; Humans; Keratosis; Male; Middle Aged; Patient Satisfaction; Scalp Dermatoses; Severity of Illness Index

2006

Low-dose 5-fluorouracil in combination with salicylic acid as a new lesion-directed option to treat topically actinic keratoses: histological and clinical study results.

The British journal of dermatology, 2011, Volume: 165, Issue:5

Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Hyaluronic Acid; Keratolytic Agents; Keratosis, Actinic; Male; Middle Aged; Salicylic Acid; Treatment Outcome

2011

Other Studies

33 other study(ies) available for diclofenac and fluorouracil

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Altered pharmacodynamics of 1-(2-tetrahydrofuryl)-5-fluorouracil by pretreatment of rats with phenobarbital, indomethacin, diclofenac sodium and carbon tetrachloride. Pharmacology, 1980, Volume: 21, Issue:5 Topics: Animals; Carbon Tetrachloride; Diclofenac; Female; Fluorouracil; Indomethacin; Microsomes, Liver; Phenobarbital; Phenylacetates; Rats; Tegafur; Time Factors	1980
New treatments for actinic keratoses. Connecticut medicine, 2002, Volume: 66, Issue:10 Topics: Administration, Topical; Aminolevulinic Acid; Aminoquinolines; Dermatologic Agents; Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis; Sunscreening Agents; United States	2002
The effect of penetration enhancers on drug delivery through skin: a QSAR study. Journal of controlled release : official journal of the Controlled Release Society, 2004, Sep-14, Volume: 99, Issue:1 Topics: Administration, Cutaneous; Animals; Benzazepines; Diclofenac; Estradiol; Fluorouracil; Humans; Hydrocortisone; In Vitro Techniques; Mice; Mice, Hairless; Molecular Structure; Proline; Pyrrolidinones; Skin Absorption; Structure-Activity Relationship; Terpenes	2004
Topical diclofenac: new preparation. Moderate efficacy in actinic keratosis. Prescrire international, 2004, Volume: 13, Issue:72 Topics: Administration, Cutaneous; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dermatologic Agents; Diclofenac; Double-Blind Method; Drug Combinations; Fluorouracil; Gels; Humans; Hyaluronic Acid; Porokeratosis; Treatment Outcome	2004
Pharmacoeconomic analysis of the treatment of multiple actinic keratoses. Journal of drugs in dermatology : JDD, 2008, Volume: 7, Issue:1 Topics: Aminolevulinic Acid; Aminoquinolines; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cryotherapy; Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis; Photochemotherapy; Treatment Outcome	2008
Role of complexes formation between drugs and penetration enhancers in transdermal delivery. International journal of pharmaceutics, 2008, Nov-03, Volume: 363, Issue:1-2 Topics: Administration, Cutaneous; Chemistry, Pharmaceutical; Computer Simulation; Diclofenac; Drug Compounding; Estradiol; Fluorouracil; Hydrocortisone; Models, Molecular; Molecular Conformation; Permeability; Pharmaceutical Preparations; Pharmaceutical Vehicles; Skin Absorption; Terpenes	2008
Drug sorption onto and release from soy protein fibers. Journal of materials science. Materials in medicine, 2009, Volume: 20, Issue:12 Topics: Biocompatible Materials; Diclofenac; Fluorouracil; Metformin; Pharmacokinetics; Soybean Proteins; Thermodynamics	2009
Drug release and its relationship with kinetic and thermodynamic parameters of drug sorption onto starch acetate fibers. Biotechnology and bioengineering, 2010, Mar-01, Volume: 105, Issue:4 Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Diclofenac; Diffusion; Fluorouracil; Hypoglycemic Agents; Kinetics; Metformin; Pharmaceutical Preparations; Starch; Thermodynamics	2010
Relationship between drug release and some physical parameters of drug sorption onto PLA fibers. Journal of biomaterials science. Polymer edition, 2010, Volume: 21, Issue:4 Topics: Diclofenac; Diffusion; Fluorouracil; Lactic Acid; Metformin; Models, Chemical; Pharmaceutical Preparations; Polyesters; Polymers; Solvents; Temperature; Thermodynamics	2010
Current management of actinic keratoses. Skin therapy letter, 2010, Volume: 15, Issue:5 Topics: Administration, Cutaneous; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinoma, Squamous Cell; Diclofenac; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Photochemotherapy; Skin Neoplasms	2010
Actinic keratosis. Patient-based approaches to adverse event management. Advance for NPs & PAs, 2010, Volume: 1, Issue:4 Topics: Administration, Topical; Aminoquinolines; Combined Modality Therapy; Cryotherapy; Dermatologic Agents; Diclofenac; Electrosurgery; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Photosensitizing Agents	2010
Solar cheilosis: an ominous precursor part II. Therapeutic perspectives. Journal of the American Academy of Dermatology, 2012, Volume: 66, Issue:2 Topics: Administration, Topical; Aminoquinolines; Biopsy; Carcinoma, Squamous Cell; Cheilitis; Combined Modality Therapy; Diagnosis, Differential; Diclofenac; Female; Fluorouracil; Humans; Imiquimod; Lip Neoplasms; Male; Middle Aged; Precancerous Conditions; Skin Neoplasms; Sunlight	2012
Patients' perceptions of topical treatments of actinic keratosis. The Journal of dermatological treatment, 2014, Volume: 25, Issue:5 Topics: Administration, Topical; Aged; Aged, 80 and over; Aminoquinolines; Antineoplastic Agents; Diclofenac; Female; Fluorouracil; Gels; Humans; Imiquimod; Keratosis, Actinic; Male; Middle Aged; Patient Acceptance of Health Care; Photochemotherapy; Precancerous Conditions; Skin Cream	2014
Drug absorption and release properties of crosslinked hydrogels based on diepoxy-terminated poly(ethylene glycol)s and aliphatic polyamines--a study on the effect of the gel molecular structure. Materials science & engineering. C, Materials for biological applications, 2013, Apr-01, Volume: 33, Issue:3 Topics: Absorption; Cross-Linking Reagents; Diclofenac; Epoxy Compounds; Fluorouracil; Hydrogels; Microscopy, Electron, Scanning; Molecular Weight; Polyamines; Polyethylene Glycols; Spectroscopy, Fourier Transform Infrared	2013
Key Opinion Leader (KOL) Consensus for actinic keratosis management in Italy: the AKTUAL Workshop. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2013, Volume: 148, Issue:5 Topics: Aminoquinolines; Carcinoma, Squamous Cell; Case Management; Clinical Trials as Topic; Cryosurgery; Diagnosis, Differential; Diclofenac; Disease Management; Disease Progression; Diterpenes; Fluorouracil; Humans; Imiquimod; Italy; Keratosis, Actinic; Laser Therapy; Neoplasms, Radiation-Induced; Photochemotherapy; Practice Guidelines as Topic; Skin Neoplasms; Sunscreening Agents; United Kingdom; United States; Watchful Waiting	2013
Topical combination of diclofenac, calcipotriol, and difluoromethylornithine has beneficial effects comparable to 5-fluorouracil for the treatment of non-melanoma skin cancer in mice. Journal of chemotherapy (Florence, Italy), 2014, Volume: 26, Issue:2 Topics: Administration, Topical; Animals; Antineoplastic Combined Chemotherapy Protocols; Calcitriol; Diclofenac; Eflornithine; Female; Fluorouracil; Mice; Mice, Hairless; Random Allocation; Skin Neoplasms	2014
A cost-utility analysis of ingenol mebutate gel for the treatment of actinic keratosis: a Scottish perspective. The European journal of health economics : HEPAC : health economics in prevention and care, 2016, Volume: 17, Issue:3 Topics: Cost-Benefit Analysis; Cryotherapy; Diclofenac; Diterpenes; Dose-Response Relationship, Drug; Fluorouracil; Humans; Keratolytic Agents; Keratosis, Actinic; Models, Econometric; Quality-Adjusted Life Years; Recurrence; Salicylic Acid; Scotland; Treatment Outcome	2016
Methods and Results Report - Evidence and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis -International League of Dermatological Societies in cooperation with the European Dermatology Forum. Journal of the European Academy of Dermatology and Venereology : JEADV, 2015, Volume: 29, Issue:11 Topics: Aminoquinolines; Antineoplastic Agents; Combined Modality Therapy; Cryotherapy; Curettage; Cyclooxygenase Inhibitors; Diclofenac; Diterpenes; Evidence-Based Medicine; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Laser Therapy; Lasers, Gas; Photochemotherapy	2015
The effect of wool hydrolysates on squamous cell carcinoma cells in vitro. Possible implications for cancer treatment. PloS one, 2017, Volume: 12, Issue:8 Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Diclofenac; Diterpenes; Fluorouracil; Humans; Keratinocytes; Protein Hydrolysates; Skin Neoplasms; Wool	2017
Management of clinical and subclinical actinic keratoses with histological and immunohistochemical assessments by confocal microscopy. Dermatologic therapy, 2018, Volume: 31, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Diclofenac; Fluorouracil; Gels; Humans; Immunohistochemistry; Keratosis, Actinic; Male; Microscopy, Confocal; Middle Aged; Scalp Dermatoses; Skin Cream	2018
Evaluation of the treatment costs and duration of topical treatments for multiple actinic keratosis based on the area of the cancerization field and not on the number of lesions. Journal of the European Academy of Dermatology and Venereology : JEADV, 2019, Volume: 33, Issue:2 Topics: Administration, Topical; Aminolevulinic Acid; Cohort Studies; Cost of Illness; Diclofenac; Diterpenes; Drug Administration Schedule; Female; Fluorouracil; Health Care Costs; Humans; Imiquimod; Italy; Keratosis, Actinic; Male; Photochemotherapy; Precancerous Conditions; Retrospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome	2019
Annales de dermatologie et de venereologie, 2019, Volume: 146 Suppl 2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cost-Benefit Analysis; Cryotherapy; Dermatologic Agents; Diclofenac; Diterpenes; Electrocoagulation; Fluorouracil; Humans; Imiquimod; Keratosis, Actinic; Laser Therapy; Photochemotherapy	2019
Evaluation of the Effect of Diclofenac Sodium and 5-Fluourasil in a 3D Cholesteatoma Cell Culture Model. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2019, Volume: 40, Issue:8 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Culture Techniques; Cholesteatoma, Middle Ear; Coculture Techniques; Diclofenac; Female; Fibroblasts; Fluorouracil; Humans; Keratinocytes; Male; Middle Aged; Otitis Media	2019