diclofenac has been researched along with enalapril in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 9 (42.86) | 29.6817 |
| 2010's | 9 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Graves, P; Kuze, K; Leahy, A; Stuhlmann, H; Wilson, P; You, G | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Avdeef, A; Tam, KY | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kähönen, M; Kalliovalkama, J; Karjala, K; Mäkynen, H; Pörsti, I; Tolvanen, JP; Wu, X | 1 |
| Bachvarov, DR; Bachvarova, M; Bouthillier, J; Houle, S; Larrivée, JF; Marceau, F | 1 |
| Brücker, G; Deray, G; Launay-Vacher, V; Levu, S; Ravaud, P; Salomon, L | 1 |
| Carvalho, MH; Cruz, MC; Fortes, ZB; Martinez, LL; Miguel, AS; Nigro, D; Oliveira, MA; Rastelli, VM; Tostes, RC; Walber, J | 1 |
| Cheng, ZJ; Finckenberg, P; Grönholm, T; Louhelainen, M; Merasto, S; Mervaala, E; Tikkanen, I | 1 |
| Björkman, S; Höglund, P; Juhlin, T | 1 |
| Erhardt, LR; Höglund, P; Jönsson, BA; Juhlin, T; Ottosson, H | 1 |
2 review(s) available for diclofenac and enalapril
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for diclofenac and enalapril
| Article | Year |
|---|---|
Cyclooxygenase inhibition causes marked impairment of renal function in elderly subjects treated with diuretics and ACE-inhibitors.
Topics: Age Factors; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Bendroflumethiazide; Cross-Over Studies; Cyclooxygenase Inhibitors; Diclofenac; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Geriatric Assessment; Glomerular Filtration Rate; Humans; Kidney Function Tests; Male; Probability; Reference Values; Risk Assessment | 2005 |
Treatments with losartan or enalapril are equally sensitive to deterioration in renal function from cyclooxygenase inhibition.
Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Cyclooxygenase 2 Inhibitors; Diclofenac; Diuretics; Enalapril; Female; Glomerular Filtration Rate; Heart Failure; Humans; Kidney; Losartan; Male; Middle Aged; Renin-Angiotensin System; Time Factors | 2007 |
17 other study(ies) available for diclofenac and enalapril
| Article | Year |
|---|---|
Heterologous expression and functional characterization of a mouse renal organic anion transporter in mammalian cells.
Topics: Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; COS Cells; Glycosylation; Histidine; In Situ Hybridization; Kidney; Kinetics; Mice; p-Aminohippuric Acid; Probenecid; Protein Processing, Post-Translational; Renal Agents; Substrate Specificity; Tunicamycin | 1999 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Losartan and enalapril therapies enhance vasodilatation in the mesenteric artery of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Diclofenac; Enalapril; Endothelium; Enzyme Inhibitors; Heart Rate; Hypertension; In Vitro Techniques; Losartan; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents; Vasodilation | 1999 |
Effect of endogenous kinins, prostanoids, and NO on kinin B1 and B2 receptor expression in the rabbit.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Diclofenac; Down-Regulation; Duodenum; Enalapril; Female; Gene Expression Regulation; Heart; Histamine; Iloprost; In Vitro Techniques; Kinins; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Prostaglandins; Rabbits; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 1999 |
Assessing residents' prescribing behavior in renal impairment.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; Cyclooxygenase Inhibitors; Diclofenac; Drug Prescriptions; Drug Utilization; Enalapril; Female; France; Gentamicins; Humans; Internship and Residency; Kidney Diseases; Male; Practice Patterns, Physicians'; Surveys and Questionnaires | 2003 |
Enalapril interferes with the effect of diclofenac on leucocyte-endothelium interaction in hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cell Adhesion Molecules; Cell Migration Inhibition; Diclofenac; Drug Interactions; Enalapril; Endothelium, Vascular; Hypertension; Leukotriene B4; Male; Rats; Rats, Inbred SHR | 2004 |
Vascular and renal effects of vasopeptidase inhibition and angiotensin-converting enzyme blockade in spontaneously diabetic Goto-Kakizaki rats.
Topics: Acetylcholine; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Blood Vessels; Diabetes Mellitus, Type 2; Diclofenac; Enalapril; Endothelium, Vascular; Kidney; Male; Metalloproteases; Neprilysin; NG-Nitroarginine Methyl Ester; Nitroprusside; Pyridines; Rats; Rats, Inbred Strains; Rats, Wistar; Sodium, Dietary; Thiazepines; Vasodilator Agents | 2005 |