diclofenac and dimethyl sulfoxide

diclofenac has been researched along with dimethyl sulfoxide in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's2 (11.11)18.2507
2000's10 (55.56)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Estler, CJ; Lepper, H; Schmitz, G; Sippel, H; Stauffert, I1
Johansson, J; Lahti, A1
Lobovkina, LA; Tsepov, LM; Vinogradova, TV1
Bernabéu, C; Betés, PO; Fresno Vara, JA; García-Martínez, JM; Lastres, P; Martín-Pérez, J1
Galetin, A; Gardner-Stephen, D; Guo, XH; Houston, JB; Mackenzie, PI; Miners, JO; Uchaipichat, V1
Hallare, AV; Köhler, HR; Triebskorn, R1
Roth, SH; Shainhouse, JZ1
Caruelle, JP; Cebrian, J; Ferry, A; Martelly, I; Vignaud, A1
Fujimoto, S; Kunimatsu, M; Mori, M; Tsushima, H1
Haap, T; Köhler, HR; Triebskorn, R1
Bookman, AAM; Grierson, LM; Naseer, Z; Shainhouse, ZJ; Simon, LS1
Heinzle, E; Niklas, J; Noor, F1
Moen, MD1
Fuller, P; Roth, SH2
Chiniforoshan, H; McArdle, P; Tabrizi, L1
Craig, DQ; Goh, CF; Hadgraft, J; Lane, ME1

Reviews

1 review(s) available for diclofenac and dimethyl sulfoxide

ArticleYear
Diclofenac sodium topical solution 1.5% w/w with dimethyl sulfoxide compared with placebo for the treatment of osteoarthritis: pooled safety results.
    Postgraduate medicine, 2011, Volume: 123, Issue:6

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dimethyl Sulfoxide; Female; Humans; Male; Middle Aged; Osteoarthritis; Pharmaceutical Solutions

2011

Trials

2 trial(s) available for diclofenac and dimethyl sulfoxide

ArticleYear
Efficacy and safety of a topical diclofenac solution (pennsaid) in the treatment of primary osteoarthritis of the knee: a randomized, double-blind, vehicle-controlled clinical trial.
    Archives of internal medicine, 2004, Oct-11, Volume: 164, Issue:18

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dimethyl Sulfoxide; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pharmaceutical Solutions; Solvents; Treatment Outcome

2004
Efficacy and safety of topical diclofenac containing dimethyl sulfoxide (DMSO) compared with those of topical placebo, DMSO vehicle and oral diclofenac for knee osteoarthritis.
    Pain, 2009, Volume: 143, Issue:3

    Topics: Activities of Daily Living; Administration, Oral; Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Dimethyl Sulfoxide; Double-Blind Method; Drug Combinations; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Osteoarthritis, Knee; Skin; Treatment Outcome

2009

Other Studies

15 other study(ies) available for diclofenac and dimethyl sulfoxide

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Toxicity of diclofenac to isolated hepatocytes.
    Journal of hepatology, 1992, Volume: 14, Issue:2-3

    Topics: Animals; Cell Survival; Cells, Cultured; Diclofenac; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Inbred Strains

1992
Topical non-steroidal anti-inflammatory drugs inhibit non-immunologic immediate contact reactions.
    Contact dermatitis, 1988, Volume: 19, Issue:3

    Topics: Acrolein; Adult; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Benzoic Acid; Dermatitis, Contact; Diclofenac; Dimethyl Sulfoxide; Female; Humans; Irritants; Male; Naproxen; Nicotinic Acids; Regional Blood Flow; Salicylates; Skin

1988
[The effect of different concentrations of dimexide and ortofen on the T-cell and neutrophil components of immunity].
    Stomatologiia, 1998, Volume: 77, Issue:3

    Topics: Acute Disease; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Neutrophils; Periapical Periodontitis; Rosette Formation; T-Lymphocytes

1998
Effect of metamizol on promyelocytic and terminally differentiated granulocytic cells. Comparative analysis with acetylsalicylic acid and diclofenac.
    Biochemical pharmacology, 2003, Jan-15, Volume: 65, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Differentiation; Cell Survival; Diclofenac; Dimethyl Sulfoxide; Dipyrone; Drug Interactions; Granulocytes; HL-60 Cells; Humans

2003
Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4

    Topics: Acetone; Animals; Blotting, Western; Caco-2 Cells; Diclofenac; Dimethyl Sulfoxide; Ethanol; Glucuronates; Glucuronosyltransferase; Humans; Hymecromone; Isoenzymes; Kinetics; Methanol; Mice; Probenecid; Solvents

2004
Developmental toxicity and stress protein responses in zebrafish embryos after exposure to diclofenac and its solvent, DMSO.
    Chemosphere, 2004, Volume: 56, Issue:7

    Topics: Analysis of Variance; Animals; Diclofenac; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Gastrula; Gene Expression Regulation; Heart Rate; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Pigmentation; Somites; Toxicity Tests, Acute; Zebrafish

2004
Effect of anti-inflammatory and antioxidant drugs on the long-term repair of severely injured mouse skeletal muscle.
    Experimental physiology, 2005, Volume: 90, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blotting, Western; Curcumin; Cyclooxygenase Inhibitors; Diclofenac; Dimethyl Sulfoxide; Electrophoresis, Polyacrylamide Gel; Indomethacin; Male; Mice; Muscle Contraction; Muscle, Skeletal; NF-kappa B; Pyrrolidines; Regeneration; Thiocarbamates

2005
Capsaicin-induced, capsazepine-insensitive relaxation of the guinea-pig ileum.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: 4-Aminopyridine; Acetylcholine; Animals; Apamin; Barium; Benzopyrans; Caffeine; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Charybdotoxin; Diclofenac; Dimethyl Sulfoxide; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Guanethidine; Guinea Pigs; Ileum; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Relaxation; Muscle, Smooth; Myosin Light Chains; Nitroarginine; Papaverine; Peptide Fragments; Phosphodiesterase Inhibitors; Phosphorylation; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Protein Serine-Threonine Kinases; Pyrazoles; Receptor, Cannabinoid, CB1; rho-Associated Kinases; Tetraethylammonium; Vasodilator Agents

2006
Acute effects of diclofenac and DMSO to Daphnia magna: immobilisation and hsp70-induction.
    Chemosphere, 2008, Volume: 73, Issue:3

    Topics: Animals; Antirheumatic Agents; Daphnia; Diclofenac; Dimethyl Sulfoxide; HSP70 Heat-Shock Proteins; Water Pollutants, Chemical

2008
Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2.
    Toxicology and applied pharmacology, 2009, Nov-01, Volume: 240, Issue:3

    Topics: Amiodarone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Citric Acid Cycle; Diclofenac; Dimethyl Sulfoxide; Humans; Liver Neoplasms; Oxidative Phosphorylation; Oxygen; Pharmaceutical Preparations; Tacrine

2009
Topical diclofenac solution.
    Drugs, 2009, Volume: 69, Issue:18

    Topics: Activities of Daily Living; Administration, Cutaneous; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diclofenac; Dimethyl Sulfoxide; Drug Administration Schedule; Free Radical Scavengers; Humans; Ontario; Osteoarthritis, Knee; Outcome Assessment, Health Care; Pain; Pain Measurement; Placebos; Randomized Controlled Trials as Topic; Skin Diseases; Solutions; Treatment Outcome

2009
Pooled safety analysis of diclofenac sodium topical solution 1.5% (w/w) in the treatment of osteoarthritis in patients aged 75 years or older.
    Clinical interventions in aging, 2012, Volume: 7

    Topics: Administration, Topical; Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Canada; Clinical Trials, Phase III as Topic; Diclofenac; Dimethyl Sulfoxide; Drug-Related Side Effects and Adverse Reactions; Female; Gastrointestinal Tract; Hand Joints; Humans; Male; Multicenter Studies as Topic; Osteoarthritis; Osteoarthritis, Knee; Skin; Solvents; United States

2012
Synthesis, crystal structure and spectroscopy of bioactive Cd(II) polymeric complex of the non-steroidal anti-inflammatory drug diclofenac sodium: antiproliferative and biological activity.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Feb-05, Volume: 136 Pt B

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Cadmium; Cattle; Cell Proliferation; Crystallography, X-Ray; Diclofenac; Dimethyl Sulfoxide; Humans; MCF-7 Cells; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Polymers; Serum Albumin, Bovine; Solutions; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Superoxide Dismutase

2015
The application of ATR-FTIR spectroscopy and multivariate data analysis to study drug crystallisation in the stratum corneum.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2017, Volume: 111

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Cluster Analysis; Crystallization; Diclofenac; Dimethyl Sulfoxide; Epidermis; Inflammation; Light; Multivariate Analysis; Pain; Principal Component Analysis; Propylene Glycol; Skin; Spectroscopy, Fourier Transform Infrared; Swine; Thermodynamics

2017