diclofenac and diflunisal

diclofenac has been researched along with diflunisal in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (13.16)	18.7374
1990's	1 (2.63)	18.2507
2000's	15 (39.47)	29.6817
2010's	14 (36.84)	24.3611
2020's	3 (7.89)	2.80

Authors

Authors	Studies
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S	1
Topliss, JG; Yoshida, F	1
Cihlar, T; Ho, ES; Mulato, AS	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM	1
Chang, TK; Ensom, MH; Kiang, TK	1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Briand, X; Faller, B; Lázaro, E; Lowe, PJ	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Kumar, M; Sinha, VR; Thareja, S	1
Arsequell, G; Blasi, D; Bosch, L; Centeno, NB; Cotrina, EY; Pinto, M; Planas, A; Quintana, J; Valencia, G; Vilà, M	1
Bellman, K; Knegtel, RM; Settimo, L	1
Anan, I; Begum, A; Brännström, K; Gharibyan, AL; Iakovleva, I; Nilsson, L; Olofsson, A; Sauer-Eriksson, AE; Walfridsson, M	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K	1
DeRose, EF; Duff, MR; Gabel, SA; Howell, EE; Krahn, JM; London, RE; Pedersen, LC	1
Mizuguchi, M; Yokoyama, T	1
Altman, R	1
Baumüller, A; Esders, K	1
Cronberg, S; Söderberg, I; Wallmark, E	1
Schlumpf, U	1
Dieppe, PA; Huskisson, EC; Jones, H; Scott, J	1
Cannell, GR; Dickinson, RG; Vesey, DA	1
Almeida, MR; Alves, I; Arsequell, G; Cardoso, I; Macedo, B; Planas, A; Saraiva, MJ; Valencia, G	1
Hartnell, NR; Wilson, JP	1
Choi, JS; Han, HK; Jin, MJ	1
Kamimura, H; Mano, Y; Usui, T	1
Davey, J	1
de Graaf, IA; Groothuis, GM; Niu, X; van der Bij, HA	1
Churakov, AV; Kuzmina, LG; Manin, AN; Manin, NG; Perlovich, GL; Surov, AO; Voronin, AP	1
Biles, CL; Broge, M; Cluck, T; Dahal, S; Dalmont, K; Gurung, T; Howard, A; Konsure, H; Poudyal, S; Rowsey, T; Shrestha, S	1

Reviews

5 review(s) available for diclofenac and diflunisal

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Transthyretin Amyloidogenesis Inhibitors: From Discovery to Current Developments. Journal of medicinal chemistry, 2020, 12-10, Volume: 63, Issue:23 Topics: Amyloid; Crystallography, X-Ray; Drug Discovery; Humans; Molecular Structure; Prealbumin	2020
[Adjuvant therapy with nonsteroidal antiphlogistics in disease of the urogenital tract]. Fortschritte der Medizin, 1984, Dec-06, Volume: 102, Issue:45 Topics: Anti-Inflammatory Agents; Aspirin; Diclofenac; Diflunisal; Escin; Flurbiprofen; Humans; Indomethacin; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Urologic Diseases	1984
[The introduction of non-steroidal antirheumatics: is there a rational therapy]. Schweizerische medizinische Wochenschrift, 1982, Aug-28, Volume: 112, Issue:35 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbazoles; Chronic Disease; Diclofenac; Diflunisal; Humans; Indomethacin; ortho-Aminobenzoates; Osteoarthritis; Phenylbutazone; Piroxicam; Rheumatic Diseases; Salicylates; Thiazines; Tolmetin	1982

Trials

1 trial(s) available for diclofenac and diflunisal

Article	Year
International experiences with diclofenac in osteoarthritis. The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Naproxen; Osteoarthritis; Random Allocation; Sulindac	1986

Other Studies

32 other study(ies) available for diclofenac and diflunisal

Article	Year
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Molecular pharmacology, 1999, Volume: 55, Issue:5 Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1 Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship	2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints. Journal of medicinal chemistry, 2004, Sep-23, Volume: 47, Issue:20 Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship	2004
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin. Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7 Topics: Humans; Kinetics; Membranes, Artificial; Permeability; Protein Binding; Serum Albumin	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Modulation of the fibrillogenesis inhibition properties of two transthyretin ligands by halogenation. Journal of medicinal chemistry, 2013, Nov-27, Volume: 56, Issue:22 Topics: Diflunisal; Flufenamic Acid; Halogenation; Humans; Kinetics; Ligands; Models, Molecular; Prealbumin; Protein Multimerization; Protein Structure, Secondary; Structure-Activity Relationship	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Enthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma. Journal of medicinal chemistry, 2015, Aug-27, Volume: 58, Issue:16 Topics: Amyloidosis; Calorimetry; Drug Design; Humans; Ligands; Models, Molecular; Plasma; Prealbumin; Protein Binding; Thermodynamics; X-Ray Diffraction	2015
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design. Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4 Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry	2020
The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase. Journal of medicinal chemistry, 2020, 08-13, Volume: 63, Issue:15 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Crystallography, X-Ray; Drug Design; Folic Acid; Folic Acid Antagonists; Humans; Models, Molecular; Tetrahydrofolate Dehydrogenase	2020
Effect on platelet aggregation of oral administration of 10 non-steroidal analgesics to humans. Scandinavian journal of haematology, 1984, Volume: 33, Issue:2 Topics: Acetaminophen; Adult; Analgesics; Aspirin; Diclofenac; Diflunisal; Epinephrine; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Oxyphenbutazone; Piroxicam; Platelet Aggregation; Thiazines; Time Factors	1984
Diclofenac sodium, diflunisal and naproxen: patient preferences for anti-inflammatory drugs in rheumatoid arthritis. Rheumatology and rehabilitation, 1982, Volume: 21, Issue:4 Topics: Adult; Aged; Arthritis, Rheumatoid; Consumer Behavior; Diclofenac; Diflunisal; Female; Humans; Male; Middle Aged; Naproxen; Patient Participation; Phenylacetates; Salicylates	1982
Inhibition of proliferation of HT-29 colon adenocarcinoma cells by carboxylate NSAIDs and their acyl glucuronides. Life sciences, 2001, Nov-21, Volume: 70, Issue:1 Topics: Acylation; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Diclofenac; Diflunisal; Dose-Response Relationship, Drug; Glucuronides; HT29 Cells; Humans; Piroxicam; Stereoisomerism; Thymidine; Tolmetin; Valproic Acid	2001
Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative. The Biochemical journal, 2004, Jul-15, Volume: 381, Issue:Pt 2 Topics: Amyloid Neuropathies; Diclofenac; Diflunisal; Flufenamic Acid; Humans; Iodine; Iodobenzoates; Molecular Structure; Prealbumin; Protein Binding; Thyroxine	2004
Replication of the Weber effect using postmarketing adverse event reports voluntarily submitted to the United States Food and Drug Administration. Pharmacotherapy, 2004, Volume: 24, Issue:6 Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Diflunisal; Epidemiologic Measurements; Flurbiprofen; Humans; Incidence; Piroxicam; Retrospective Studies; Sulindac; Time Factors; United Kingdom; United States; United States Food and Drug Administration	2004
Role of monocarboxylic acid transporters in the cellular uptake of NSAIDs. The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzoic Acid; Caco-2 Cells; Carbon Radioisotopes; Diclofenac; Diflunisal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Ketoprofen; Lactic Acid; Monocarboxylic Acid Transporters; Naproxen; Permeability	2005
In vitro inhibitory effects of non-steroidal anti-inflammatory drugs on 4-methylumbelliferone glucuronidation in recombinant human UDP-glucuronosyltransferase 1A9--potent inhibition by niflumic acid. Biopharmaceutics & drug disposition, 2006, Volume: 27, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Diflunisal; Enzyme Inhibitors; Glucuronides; Glucuronosyltransferase; Humans; Hymecromone; In Vitro Techniques; Kinetics; Niflumic Acid; Recombinant Proteins; UDP-Glucuronosyltransferase 1A9	2006
The advantages and limitations of the analgesics available for control of postoperative pain after a dental procedure. SAAD digest, 2013, Volume: 29 Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Codeine; Cyclooxygenase 2 Inhibitors; Dental Care; Diclofenac; Diflunisal; Drug Combinations; Humans; Ibuprofen; Narcotics; Oral Surgical Procedures; Pain, Postoperative; Tramadol	2013
Precision cut intestinal slices are an appropriate ex vivo model to study NSAID-induced intestinal toxicity in rats. Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:7 Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caspase 9; Cell Survival; Diclofenac; Diflunisal; Endoplasmic Reticulum Stress; Gene Expression; Glutathione; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Indomethacin; Jejunum; Male; Naproxen; Rats, Wistar; Tissue Culture Techniques	2014
Pharmaceutical cocrystals of diflunisal and diclofenac with theophylline. Molecular pharmaceutics, 2014, Oct-06, Volume: 11, Issue:10 Topics: Calorimetry, Differential Scanning; Diclofenac; Diflunisal; Models, Molecular; Solubility; Theophylline	2014
Nonsteroidal Anti-inflammatory Drugs (NSAIDS) Inhibit the Growth and Reproduction of Chaetomium globosum and Other Fungi Associated with Water-Damaged Buildings. Mycopathologia, 2017, Volume: 182, Issue:11-12 Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Aspergillus; Aspirin; Cell Proliferation; Chaetomium; Diclofenac; Diflunisal; Fusarium; Germination; Humans; Ibuprofen; Lung Diseases, Fungal; Microbial Sensitivity Tests; Mycoses; Stachybotrys	2017