diclofenac and chlorpropamide

diclofenac has been researched along with chlorpropamide in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (26.32)29.6817
2010's13 (68.42)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cerioni, L; Cuffini, SL; Faudone, S; Pérez, SC; Wolfenson, AE1
Baird, JA; Taylor, LS1
Harris, MT; Taylor, LS; Zhu, Q1
Algeelani, S; Alkhelb, D; Greenblatt, DJ1
Glatz, Z; Michalcová, L; Nevídalová, H1

Reviews

1 review(s) available for diclofenac and chlorpropamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

18 other study(ies) available for diclofenac and chlorpropamide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Utilization of pure nuclear quadrupole resonance spectroscopy for the study of pharmaceutical crystal forms.
    International journal of pharmaceutics, 2005, Jul-14, Volume: 298, Issue:1

    Topics: Chlorpropamide; Crystallization; Diclofenac; Magnetic Resonance Spectroscopy; X-Ray Diffraction

2005
Evaluation and modeling of the eutectic composition of various drug-polyethylene glycol solid dispersions.
    Pharmaceutical development and technology, 2011, Volume: 16, Issue:3

    Topics: Chlorpropamide; Crystallization; Diclofenac; Drug Carriers; Haloperidol; Loratadine; Models, Chemical; Phase Transition; Polyethylene Glycols; Spectroscopy, Fourier Transform Infrared; Transition Temperature

2011
Evaluation of the microstructure of semicrystalline solid dispersions.
    Molecular pharmaceutics, 2010, Aug-02, Volume: 7, Issue:4

    Topics: Calorimetry, Differential Scanning; Chlorpropamide; Diclofenac; Excipients; Haloperidol; Microscopy, Atomic Force; Pharmaceutical Preparations; Polyethylene Glycols; Scattering, Small Angle; Solubility; X-Ray Diffraction

2010
Inhibitory effects of sulfonylureas and non-steroidal anti-inflammatory drugs on in vitro metabolism of canagliflozin in human liver microsomes.
    Biopharmaceutics & drug disposition, 2018, Volume: 39, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Canagliflozin; Chlorpropamide; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Gliclazide; Humans; Hypoglycemic Agents; Microsomes, Liver; Niflumic Acid; Sulfonylurea Compounds

2018
Applicability of capillary electrophoresis-frontal analysis for displacement studies: Effect of several drugs on l-tryptophan and lidocaine binding to human serum albumin.
    Journal of separation science, 2020, Volume: 43, Issue:22

    Topics: Binding Sites; Chlorpropamide; Diclofenac; Electrophoresis, Capillary; Flurbiprofen; Humans; Ibuprofen; Lidocaine; Phenylbutazone; Serum Albumin, Human; Tolbutamide; Tryptophan

2020