diclofenac has been researched along with betadex in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (7.69) | 18.2507 |
| 2000's | 9 (23.08) | 29.6817 |
| 2010's | 26 (66.67) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Franchimont, P; Reginster, JY | 1 |
| Cwiertnia, B; Hladon, T; Stobiecki, M | 1 |
| Arancibia, JA; Escandar, GM | 1 |
| Asakawa, N; Ishihama, Y; Miwa, T | 1 |
| Chadha, R; Jain, DV; Kashid, N; Kumar, A | 1 |
| Dias, MM; Hadgraft, J; Pellett, MA; Raghavan, SL | 1 |
| Chadha, R; Jain, DV; Kashid, N | 1 |
| Pina, ME; Santos, H; Sousa, JJ; Veiga, F | 1 |
| Baia, M; Iliescu, T; Miclăuş, V | 1 |
| Alvarez-Lorenzo, C; Concheiro, A; Rodriguez-Perez, A; Rodriguez-Tenreiro, C; Torres-Labandeira, JJ | 1 |
| Ennas, G; Fadda, AM; Loy, G; Manca, ML; Sinico, C; Valenti, D; Zaru, M | 1 |
| Alvarez-Lorenzo, C; Bucio, E; Burillo, G; Concheiro, A; Nava-Ortíz, CA | 1 |
| Awari, JG; Kilor, VA; Sapkal, NP; Shewale, BD | 1 |
| Granero, GE; Longhi, MR; Mora, MJ | 1 |
| Brundu, A; Cerri, G; Cossu, M; Gavini, E; Giunchedi, P; Rassu, G; Sorrenti, M; Spada, G | 1 |
| Bandy, D; Carr, DB; Christensen, K; Daniels, S; Ernst, CC; Hamilton, DA; Mermelstein, FH; Wang, J | 1 |
| Ducharme, MP; Gugliotta, B; Müller, M; Oraha, AZ; Rusca, A; Zeitlinger, M | 1 |
| Basit, AW; Carvalho, RA; Figueiras, A; Gonsalves, A; Rocha Gonsalves, AM; Serra, AC; Veiga, FJ; Vieira, AC | 1 |
| Bouchard, A; Carr, DB; Hamilton, DA; Lacouture, PG; Lang, E; Madden, D; McDonnell Moorehead, T; Sprenger, CR; Wright, C | 1 |
| Dietrich, T; Gugliotta, B; Leeson, R; Petersen, B | 1 |
| Carr, DB; Hamilton, DA; Lacouture, PG; Mermelstein, F; Ramaiya, A; Wright, C | 1 |
| Bernasconi, S; Chiarello, E; Giannini, S; Gugliotta, B | 1 |
| Cardì, F; Drago, F; Gugliotta, B; Piazza, C; Salomone, S; Vitale, DC | 1 |
| De Luca, M; Ioele, G; Ragno, G; Tavano, L | 1 |
| Ascenzi, P; Bucatariu, S; Constantin, M; Fundueanu, G; Harabagiu, V | 1 |
| Basit, AW; Gonsalves, AM; Murdan, S; Serra, AC; Veiga, FJ; Vieira, AC | 2 |
| Dong, K; Wang, K; Xing, J; Xu, W; Yan, Y; Zhang, L; Zhao, G | 1 |
| Lenik, J | 1 |
| Hirun, N; Klaewklod, A; Li, L; Sangfai, T; Tantishaiyakul, V | 1 |
| Blair, HA; Plosker, GL | 1 |
| Abdel Jalil, M; El-Sabawi, D; Hamdan, II | 1 |
| Bonagura, AC; Cenami, R; Cimmaruta, D; Fiorentino, S; Fossati, T; Rossi, F; Scavone, C; Torella, M | 1 |
| Carr, DB; Daniels, SE; Gan, TJ; Lacouture, PG; Min, LH; Reyes, CR; Singla, N | 1 |
| Hoy, SM | 1 |
| Caprini, C; Colotta, V; Del Bubba, M; Furlanetto, S; Orlandini, S; Pasquini, B; Squarcialupi, L | 1 |
| Carr, DB; Daniels, SE; Gan, TJ; Hamilton, DA; Johnson, O; Lacouture, PG; Min, LH; Reyes, CR; Singla, N | 1 |
| Adhikary, P; Azmeera, V; Krishnamoorthi, S; Kumar, K; Tungala, K | 1 |
| Goto, S; Hiroshige, R; Kasai, T; Okumura, Y; Tsunoda, C; Yokoyama, H | 1 |
4 review(s) available for diclofenac and betadex
| Article | Year |
|---|---|
Piroxicam-beta-cyclodextrin in the treatment of acute pain of rheumatic disease.
Topics: Acute Disease; Adult; beta-Cyclodextrins; Controlled Clinical Trials as Topic; Cyclodextrins; Diclofenac; Dipyrone; Drug Combinations; Etodolac; Humans; Ketoprofen; Middle Aged; Pain; Piroxicam; Rheumatic Diseases | 1993 |
Diclofenac sodium injection (akis(®), dicloin (®)): a review of its use in the management of pain.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adult; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Chemistry, Pharmaceutical; Diclofenac; Humans; Injections; Pain; Pain, Postoperative | 2015 |
Efficacy and Safety Profile of Diclofenac/Cyclodextrin and Progesterone/Cyclodextrin Formulations: A Review of the Literature Data.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Biological Availability; Cyclodextrins; Diclofenac; Drug Compounding; Drug Therapy, Combination; Female; Humans; Male; Pain; Permeability; Pregnancy; Progesterone; Solubility; Treatment Outcome | 2016 |
Diclofenac Sodium Bolus Injection (Dyloject(TM)): A Review in Acute Pain Management.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Clinical Trials, Phase III as Topic; Diclofenac; Humans; Injections, Intravenous; Multicenter Studies as Topic; Pain Management | 2016 |
9 trial(s) available for diclofenac and betadex
| Article | Year |
|---|---|
A double-blind placebo-controlled comparison of a novel formulation of intravenous diclofenac and ketorolac for postoperative third molar extraction pain.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adolescent; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Diclofenac; Double-Blind Method; Drug Combinations; Female; Humans; Injections, Intravenous; Kaplan-Meier Estimate; Ketorolac; Male; Middle Aged; Molar, Third; Pain Measurement; Pain, Postoperative; Statistics, Nonparametric; Tooth Extraction; Young Adult | 2011 |
Pharmacokinetics of a new diclofenac sodium formulation developed for subcutaneous and intramuscular administration.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adult; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Chemistry, Pharmaceutical; Cross-Over Studies; Diclofenac; Female; Humans; Injections, Intramuscular; Injections, Subcutaneous; Male | 2012 |
Effects of injectable HPβCD-diclofenac on the human delayed rectifier potassium channel current in vitro and on proarrhythmic QTc in vivo.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Aza Compounds; beta-Cyclodextrins; Cross-Over Studies; Diclofenac; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Fluoroquinolones; HEK293 Cells; Humans; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Quinolines; Young Adult | 2013 |
Efficacy and safety of low dose subcutaneous diclofenac in the management of acute pain: a randomized double-blind trial.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Acute Pain; Adolescent; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Excipients; Female; Humans; Injections, Subcutaneous; Male; Middle Aged; Sample Size; Visual Analog Scale; Young Adult | 2014 |
Single-dose and multiple-dose pharmacokinetics and dose proportionality of intravenous and intramuscular HPβCD-diclofenac (Dyloject) compared with other diclofenac formulations.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; beta-Cyclodextrins; Biological Availability; Cross-Over Studies; Diclofenac; Dose-Response Relationship, Drug; Excipients; Female; Humans; Infusions, Intravenous; Injections, Intramuscular; Male | 2013 |
Subcutaneous injection of diclofenac for the treatment of pain following minor orthopedic surgery (DIRECT study): a randomized trial.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Diclofenac; Excipients; Female; Humans; Injections, Intramuscular; Injections, Subcutaneous; Male; Middle Aged; Orthopedic Procedures; Pain, Postoperative; Treatment Outcome; Young Adult | 2015 |
Pharmacokinetics of a new subcutaneous diclofenac formulation administered to three body sites: quadriceps, gluteus, and abdomen.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Abdominal Wall; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; beta-Cyclodextrins; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Diclofenac; Humans; Injections, Subcutaneous; Muscle, Skeletal; Pilot Projects | 2014 |
Cardiovascular safety of hydroxypropyl-β-cyclodextrin-diclofenac in the management of acute postsurgical pain: a pooled analysis of 2 randomized, double-blind, placebo- and active comparator-controlled phase III clinical trials.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Acute Pain; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Cardiovascular Diseases; Diclofenac; Double-Blind Method; Excipients; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pain, Postoperative; Young Adult | 2016 |
A Pooled Analysis Evaluating Renal Safety in Placebo- and Active Comparator-Controlled Phase III Trials of Multiple-Dose Injectable HPβCD-Diclofenac in Subjects with Acute Postoperative Pain.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Diclofenac; Double-Blind Method; Female; Humans; Kidney; Male; Middle Aged; Pain, Postoperative; Young Adult | 2016 |
26 other study(ies) available for diclofenac and betadex
| Article | Year |
|---|---|
Stability of diclofenac sodium in the inclusion complex with beta-cyclodextrin in the solid state.
Topics: beta-Cyclodextrins; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Cyclodextrins; Diclofenac; Drug Stability; Excipients; Gas Chromatography-Mass Spectrometry; Hot Temperature; Kinetics; Magnetic Resonance Spectroscopy; Thermodynamics; X-Ray Diffraction | 1999 |
Complexation study of diclofenac with beta-cyclodextrin and spectrofluorimetric determination.
Topics: Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Cyclodextrins; Diclofenac; Magnetic Resonance Spectroscopy; Pharmaceutical Preparations; Potentiometry; Spectrometry, Fluorescence; Spectrophotometry | 1999 |
Drug-plasma protein binding assay by electrokinetic chromatography-frontal analysis.
Topics: beta-Cyclodextrins; Blood Proteins; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Diclofenac; Electrophoresis, Capillary; Humans; Ketoprofen; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Serum Albumin; Sulfathiazole; Sulfathiazoles; Warfarin | 2002 |
Calorimetric studies of diclofenac sodium in aqueous solution of cyclodextrin and water-ethanol mixtures.
Topics: Algorithms; beta-Cyclodextrins; Calorimetry; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Cyclodextrins; Diclofenac; Entropy; Ethanol; Hot Temperature; Solubility; Thermodynamics; Water | 2002 |
The effect of beta-cyclodextrins on the permeation of diclofenac from supersaturated solutions.
Topics: beta-Cyclodextrins; Cyclodextrins; Diclofenac; Permeability; Pharmaceutical Solutions; Solubility | 2003 |
Kinetics of degradation of diclofenac sodium in aqueous solution determined by a calorimetric method.
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Calorimetry; Cyclodextrins; Diclofenac; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Solutions; Thermodynamics | 2003 |
Compaction, compression and drug release characteristics of xanthan gum pellets of different compositions.
Topics: beta-Cyclodextrins; Calcium Phosphates; Chemistry, Pharmaceutical; Compressive Strength; Diclofenac; Drug Compounding; Excipients; Particle Size; Polysaccharides, Bacterial; Porosity; Powders; Surface Properties; Tablets; Time Factors | 2004 |
A Raman spectroscopic study of the diclofenac sodium-beta-cyclodextrin interaction.
Topics: beta-Cyclodextrins; Diclofenac; Drug Interactions; Spectrum Analysis, Raman | 2004 |
New cyclodextrin hydrogels cross-linked with diglycidylethers with a high drug loading and controlled release ability.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Cross-Linking Reagents; Cyclodextrins; Delayed-Action Preparations; Diclofenac; Hydrogels; Oxazines; Pharmaceutical Preparations; Rheology; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2006 |
Diclofenac-beta-cyclodextrin binary systems: physicochemical characterization and in vitro dissolution and diffusion studies.
Topics: beta-Cyclodextrins; Chemical Phenomena; Chemistry, Physical; Diclofenac; Diffusion; Solubility | 2005 |
Cyclodextrin-functionalized polyethylene and polypropylene as biocompatible materials for diclofenac delivery.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Anti-Inflammatory Agents, Non-Steroidal; BALB 3T3 Cells; beta-Cyclodextrins; Calorimetry, Differential Scanning; Cell Survival; Chemistry, Pharmaceutical; Coated Materials, Biocompatible; Diclofenac; Drug Carriers; Drug Compounding; Epoxy Compounds; Fibroblasts; Friction; Gamma Rays; Kinetics; Methacrylates; Mice; Microscopy, Electron, Scanning; Polyethylene; Polypropylenes; Solubility; Spectroscopy, Fourier Transform Infrared; Surface Properties; Technology, Pharmaceutical; Temperature; Wettability | 2009 |
Development and characterization of enteric-coated immediate-release pellets of aceclofenac by extrusion/spheronization technique using kappa-carrageenan as a pelletizing agent.
Topics: Acrylic Resins; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Biological Availability; Carrageenan; Chemistry, Pharmaceutical; Diclofenac; Drug Implants; Excipients; Lactose; Particle Size; Pharmaceutical Preparations; Polymers; Povidone; Solubility | 2010 |
Synthesis and characterization of binary and ternary complexes of diclofenac with a methyl-beta-CD and monoethanolamine and in vitro transdermal evaluation.
Topics: beta-Cyclodextrins; Calorimetry, Differential Scanning; Diclofenac; Ethanolamine; Humans; Magnetic Resonance Spectroscopy; Permeability; Skin; Skin Absorption; Solubility; Thermogravimetry | 2010 |
Development of solid nanoparticles based on hydroxypropyl-β-cyclodextrin aimed for the colonic transmucosal delivery of diclofenac sodium.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Mucosal; Animals; beta-Cyclodextrins; Caco-2 Cells; Cell Survival; Chemistry, Pharmaceutical; Colon; Crystallization; Diclofenac; Drug Carriers; Emulsions; Humans; Nanoparticles; Particle Size; Permeability; Polymethacrylic Acids; Swine | 2011 |
Microwave synthesis and in vitro stability of diclofenac-β-cyclodextrin conjugate for colon delivery.
Topics: Anaerobiosis; beta-Cyclodextrins; Body Fluids; Chromatography, High Pressure Liquid; Colon; Diclofenac; Drug Carriers; Drug Delivery Systems; Drug Stability; Feces; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Microwaves; Prodrugs; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2013 |
The difficulties for a photolabile drug in topical formulations: the case of diclofenac.
Topics: Absorption, Radiation; Administration, Cutaneous; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Chemistry, Pharmaceutical; Cinnamates; Diclofenac; Drug Stability; Excipients; Gels; Kinetics; Least-Squares Analysis; Models, Chemical; Multivariate Analysis; Photolysis; Salicylates; Technology, Pharmaceutical | 2014 |
Do cyclodextrins bound to dextran microspheres act as sustained delivery systems of drugs?
Topics: alpha-Cyclodextrins; beta-Cyclodextrins; Chemistry, Pharmaceutical; Chromatography, Liquid; Cyclodextrins; Delayed-Action Preparations; Dextrans; Diclofenac; Drug Carriers; gamma-Cyclodextrins; Indoles; Kinetics; Microspheres; Models, Chemical; Nitrophenols; Parabens; Solubility; Technology, Pharmaceutical | 2014 |
Influence of feeding regimens on rat gut fluids and colonic metabolism of diclofenac-β-cyclodextrin.
Topics: Animals; beta-Cyclodextrins; Colon; Diclofenac; Diet; Drug Stability; Fasting; Gastrointestinal Absorption; Gastrointestinal Transit; Hydrogen-Ion Concentration; Male; Prodrugs; Rats, Wistar; Sulfasalazine | 2014 |
Hydroxypropyl-β-cyclodextrin grafted polyethyleneimine used as transdermal penetration enhancer of diclofenac sodium.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Cutaneous; Animals; beta-Cyclodextrins; Diclofenac; Drug Delivery Systems; Hydrophobic and Hydrophilic Interactions; Kinetics; Mice; Polyethyleneimine; Skin; Skin Absorption; Tissue Distribution | 2014 |
A new potentiometric electrode incorporating functionalized β-cyclodextrins for diclofenac determination.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Diclofenac; Dielectric Spectroscopy; Electrodes; Humans; Hydrogen-Ion Concentration; Ions; Polyvinyl Chloride; Potentiometry; Tablets | 2014 |
Characterization of supramolecular gels based on β-cyclodextrin and polyethyleneglycol and their potential use for topical drug delivery.
Topics: Animals; Animals, Newborn; beta-Cyclodextrins; Calorimetry, Differential Scanning; Cellulose; Diclofenac; Drug Delivery Systems; Gels; Humans; Microscopy; Nephelometry and Turbidimetry; Permeability; Polyethylene Glycols; Rheology; Skin; Spectroscopy, Fourier Transform Infrared; Sus scrofa; Temperature | 2015 |
Potential interaction between zinc ions and a cyclodextrin-based diclofenac formulation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Biological Availability; Calorimetry, Differential Scanning; Diclofenac; Drug Combinations; Drug Interactions; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Zinc | 2016 |
Diclofenac-β-cyclodextrin for colonic drug targeting: In vivo performance in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Colon; Diclofenac; Drug Delivery Systems; Drug Liberation; Intestinal Absorption; Male; Prodrugs; Rats, Wistar; Sulfasalazine | 2016 |
A comprehensive strategy in the development of a cyclodextrin-modified microemulsion electrokinetic chromatographic method for the assay of diclofenac and its impurities: Mixture-process variable experiments and quality by design.
Topics: beta-Cyclodextrins; Chemistry, Pharmaceutical; Chromatography; Diclofenac; Electrophoresis, Capillary; Reproducibility of Results | 2016 |
Solution and microwave assisted synthesis of β-Cyclodextrin grafted polyacrylamide: Water treatment and In-vitro drug release study.
Topics: Acrylic Resins; beta-Cyclodextrins; Chemistry Techniques, Synthetic; Diclofenac; Drug Carriers; Drug Liberation; Flocculation; Hydrolysis; Microwaves; Polymerization; Solutions; Wastewater; Water Purification | 2017 |
Optimization of the stability constants of the ternary system of diclofenac/famotidine/β-cyclodextrin by nonlinear least-squares method using theoretical equations.
Topics: beta-Cyclodextrins; Cyclodextrins; Diclofenac; Famotidine; Solubility | 2023 |