diclofenac has been researched along with ascorbic acid in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.45) | 18.7374 |
| 1990's | 2 (6.45) | 18.2507 |
| 2000's | 11 (35.48) | 29.6817 |
| 2010's | 14 (45.16) | 24.3611 |
| 2020's | 2 (6.45) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bansal, P; Gopalan Kutty, N; Manohara Reddy, SA; Mudgal, J; Rao, CM; Srinivasan, KK; Vasanthraju, SG | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Damale, M; Kauthale, S; Pawar, R; Sangshetti, J; Tekale, S | 1 |
| Asif, M; Husain, A; Iqbal, MA; Iram, F; Khan, SA | 1 |
| Agafonova, NA; Borisevich, SS; Burgart, YV; Chupakhin, ON; Evstigneeva, NP; Gerasimova, NA; Krasnykh, OP; Kungurov, NV; Kushch, SO; Makhaeva, GF; Maslova, VV; Rudakova, EV; Saloutin, VI; Shchegolkov, EV; Solodnikov, SY; Triandafilova, GA; Ulitko, MV; Zilberberg, NV | 1 |
| Jávor, T; Nagy, S; Past, T; Tárnok, F | 1 |
| Nishihata, T; Rytting, JH; Sakai, K; Takahashi, K | 1 |
| Cartier, LL; Chan, KK; Lau, HS; Maloney, JA; Rackley, RJ; Sawchuk, RJ | 1 |
| Egashira, T; Kudo, Y; Takayama, F; Yamanaka, Y | 1 |
| Deby, CM; Deby-Dupont, GP; Henrotin, YE; Lamy, MM; Mouithys-Mickalad, AM; Reginster, JY; Zheng, SX | 1 |
| Biondi, C; Compagnone, D; Dalpiaz, A; Ferraro, L; Manfredini, S; Pavan, B; Prasad, P; Scaglianti, M; Scatturin, A; Tanganelli, S; Vertuani, S | 1 |
| Basu, S; Berne, C; Lind, L; Lithell, H; Millgård, J; Steer, P; Vessby, B | 1 |
| Biondi, C; Bortolotti, F; Dalpiaz, A; Ferraro, L; Manfredini, S; Pavan, B; Prasad, P; Scaglianti, M; Scatturin, A; Tanganelli, S; Vitali, F | 1 |
| Joshi, A; Macfarlane, TV; Parara, E | 1 |
| Misawa, M; Sakai, H | 1 |
| Biondi, C; Bortolotti, F; Dalpiaz, A; Manfredini, S; Pavan, B; Scaglianti, M; Scatturin, A; Vitali, F | 1 |
| Liu, ZQ; Tang, YZ | 1 |
| Juvekar, AR; Malpure, PP; Shah, AS | 1 |
| Capkin, E; Karkucak, M; Serdaroğlu, M; Tosun, M; Yayli, S | 1 |
| Arora, B; Arora, R; Bali, M; Bansal, S; Gill, NS; Muthuraman, A; Sharma, PD; Sood, S | 1 |
| Boerma, JS; Commandeur, JN; Vermeulen, NP | 1 |
| De Luca, M; Ioele, G; Muzzalupo, R; Picci, N; Ragno, G; Tavano, L | 1 |
| Hofmann, MA; Sintov, AC | 1 |
| El-Shafei, RA; Saleh, RM | 1 |
| Heidarian, E; Nikoukar, M; Nouri, A | 1 |
| Ahmed, T; Ahsan, CR; Al Shoyaib, A; Archie, SR; Chowdhury, FA; Faruk, A | 1 |
| Akhila, M; Alwala, A; Badam, R; Bontala, P; Chaitanya, NC; Chintada, S; Inamdar, P; Mannava, H; Saawarn, N; Siva Prasad Reddy, G; Srinivas, P | 1 |
3 review(s) available for diclofenac and ascorbic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Molecular Structure | 2019 |
Ochronosis in differential diagnosis of patients with chronic backache: a review of the literature.
Topics: Alkaptonuria; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Ascorbic Acid; Back Pain; Calcinosis; Chronic Disease; Diagnosis, Differential; Diclofenac; Homogentisic Acid; Humans; Intervertebral Disc; Male; Middle Aged; Ochronosis; Radiography; Treatment Outcome; Vitamins | 2007 |
1 trial(s) available for diclofenac and ascorbic acid
| Article | Year |
|---|---|
A double-blind randomised controlled clinical trial of the effect of preoperative ibuprofen, diclofenac, paracetamol with codeine and placebo tablets for relief of postoperative pain after removal of impacted third molars.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Ascorbic Acid; Codeine; Diclofenac; Double-Blind Method; Epidemiologic Methods; Female; Humans; Ibuprofen; Male; Middle Aged; Molar, Third; Pain Measurement; Pain, Postoperative; Premedication; Tooth Extraction; Tooth, Impacted; Treatment Outcome | 2004 |
27 other study(ies) available for diclofenac and ascorbic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Antioxidant, anti-inflammatory and anti-hyperglycaemic activities of heterocyclic homoprostanoid derivatives.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Glucose Tolerance Test; Heterocyclic Compounds; Hypoglycemic Agents; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mice; Prostaglandins; Rats; Spectrometry, Mass, Electrospray Ionization | 2011 |
Synthesis, antioxidant, antifungal, molecular docking and ADMET studies of some thiazolyl hydrazones.
Topics: Antifungal Agents; Antioxidants; Aspergillus flavus; Aspergillus niger; Candida; Computer Simulation; Dose-Response Relationship, Drug; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2017 |
Multiple biological active 4-aminopyrazoles containing trifluoromethyl and their 4-nitroso-precursors: Synthesis and evaluation.
Topics: Animals; Bacteria; Drug Screening Assays, Antitumor; Epidermophyton; HeLa Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Nitroso Compounds; Pyrazoles; Rats, Sprague-Dawley; Structure-Activity Relationship; Trichophyton | 2020 |
Cytoprotective effect of free radical scavengers against mucosal damage produced by different antirheumatic drugs.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Ascorbic Acid; Aspirin; Diclofenac; Female; Free Radicals; Gastric Mucosa; Indomethacin; Male; Penicillamine; Quinolines; Rats; Solubility; Thioctic Acid; Vitamin A; Vitamin E | 1986 |
Effects of dithiothreitol and ascorbate on the penetration of diclofenac across excised rat dorsal skin.
Topics: Animals; Ascorbic Acid; Diclofenac; Dithiothreitol; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Skin Absorption | 1988 |
Analysis of diclofenac and four of its metabolites in human urine by HPLC.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Calibration; Chromatography, High Pressure Liquid; Diclofenac; Drug Stability; Female; Humans; Hydroxylation; Male; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Solvents | 1995 |
Effects of anti-free radical interventions on phosphatidylcholine hydroperoxide in plasma after ischemia-reperfusion in the liver of rats.
Topics: Animals; Ascorbic Acid; Chromatography, High Pressure Liquid; Diclofenac; Free Radicals; Ischemia; Liver; Male; Phosphatidylcholines; Rats; Rats, Wistar; Reperfusion Injury; Time Factors | 1993 |
In vitro study of the antioxidant properties of non steroidal anti-inflammatory drugs by chemiluminescence and electron spin resonance (ESR).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Chlorine; Diclofenac; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; In Vitro Techniques; Indicators and Reagents; Indomethacin; Iron; Kinetics; Lipid Peroxidation; Luminescent Measurements; Neutrophil Activation; Neutrophils; Nitrates; Reactive Oxygen Species; Sodium Hypochlorite; Spectrophotometry, Ultraviolet; Sulfonamides; Tetradecanoylphorbol Acetate | 2000 |
Design, synthesis and activity of ascorbic acid prodrugs of nipecotic, kynurenic and diclophenamic acids, liable to increase neurotropic activity.
Topics: Animals; Ascorbic Acid; Biological Transport; Cell Line; Central Nervous System Agents; Diclofenac; Humans; Kinetics; Kynurenic Acid; Mice; Nipecotic Acids; Organic Anion Transporters, Sodium-Dependent; Prodrugs; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Seizures; Sodium-Coupled Vitamin C Transporters; Structure-Activity Relationship; Symporters | 2002 |
Vitamin C, diclophenac, and L-arginine protect endothelium-dependent vasodilation against elevated circulating fatty acid levels in humans.
Topics: Adult; alpha-Linolenic Acid; Anticoagulants; Arginine; Ascorbic Acid; Cyclooxygenase Inhibitors; Diclofenac; Endothelium, Vascular; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Female; Forearm; Free Radical Scavengers; Heparin; Humans; Infusions, Intravenous; Male; Reference Values; Regional Blood Flow; Sweden; Tocopherols; Triglycerides; Vasodilation | 2003 |
Transporter-mediated effects of diclofenamic acid and its ascorbyl pro-drug in the in vivo neurotropic activity of ascorbyl nipecotic acid conjugate.
Topics: Animals; Ascorbic Acid; Brain; Cell Line; Diclofenac; Humans; Male; Mice; Nipecotic Acids; Organic Anion Transporters, Sodium-Dependent; Prodrugs; Seizures; Sodium-Coupled Vitamin C Transporters; Symporters | 2004 |
Effect of sodium azulene sulfonate on capsaicin-induced pharyngitis in rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Azulenes; Capsaicin; Cyclooxygenase Inhibitors; Diclofenac; Exudates and Transudates; Male; Pharyngitis; Povidone; Rats; Rats, Wistar; Receptors, Drug; Ruthenium Red; Sesquiterpenes | 2005 |
Vitamin C and 6-amino-vitamin C conjugates of diclofenac: synthesis and evaluation.
Topics: Ascorbic Acid; Biological Transport; Carbon Radioisotopes; Cell Line; Chromatography, High Pressure Liquid; Diclofenac; Drug Carriers; Drug Evaluation, Preclinical; Half-Life; Humans; Organic Anion Transporters, Sodium-Dependent; Prodrugs; Sodium-Coupled Vitamin C Transporters; Symporters; Time Factors | 2005 |
Evaluation of the free-radical-scavenging activity of diclofenac acid on the free-radical-induced haemolysis of human erythrocytes.
Topics: Amidines; Ascorbic Acid; Chromans; Diclofenac; Dose-Response Relationship, Drug; Drug Combinations; Erythrocytes; Free Radical Scavengers; Free Radicals; Hemolysis; Humans; In Vitro Techniques; Solubility | 2006 |
Antioxidant and anti-inflammatory activity of extract obtained from Aspergillus candidus MTCC 2202 broth filtrate.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Aspergillus; Biphenyl Compounds; Butylated Hydroxyanisole; Cations; Culture Media; Diclofenac; Edema; Free Radicals; Hydrazines; Phenol; Picrates; Rats | 2006 |
Antioxidant, anti-inflammatory and analgesic potential of the Citrus decumana L. peel extract.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Citrus; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Male; Mice; Morphine; Pain; Plant Extracts; Rats; Rats, Wistar; Solvents | 2009 |
One-electron oxidation of diclofenac by human cytochrome P450s as a potential bioactivation mechanism for formation of 2'-(glutathion-S-yl)-deschloro-diclofenac.
Topics: Ascorbic Acid; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Diclofenac; Electrons; Glutathione; Hemeproteins; Horseradish Peroxidase; Humans; Iron; Metabolic Networks and Pathways; Microsomes, Liver; Oxidation-Reduction; Oxygenases; Recombinant Proteins; Time Factors | 2014 |
Photostability and ex-vivo permeation studies on diclofenac in topical niosomal formulations.
Topics: Administration, Cutaneous; Animals; Ascorbic Acid; Chemical Phenomena; Chemistry, Pharmaceutical; Diclofenac; Drug Stability; Gels; Liposomes; Microscopy, Electron, Transmission; Particle Size; Photolysis; Rabbits; Skin Absorption | 2015 |
A novel thermo-mechanical system enhanced transdermal delivery of hydrophilic active agents by fractional ablation.
Topics: Animals; Ascorbic Acid; Diclofenac; Drug Delivery Systems; Hot Temperature; Humans; Injections, Intradermal; Phenolsulfonphthalein; Skin; Skin Absorption; Swine; Verapamil | 2016 |
Pharmacological effects of Vitamin C & E on Diclofenac Sodium intoxicated Rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Cytoprotection; Diclofenac; Disease Models, Animal; Kidney; Male; Oxidative Stress; Rats, Wistar; Uremia; Vitamin E | 2016 |
Effects of N-acetyl cysteine on oxidative stress and TNF-α gene expression in diclofenac-induced hepatotoxicity in rats.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Catalase; Chemical and Drug Induced Liver Injury; Diclofenac; Gene Expression; Lipids; Liver; Liver Function Tests; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Silymarin; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2017 |
Evaluation of the Anti-Inflammatory Activities of Diclofenac Sodium, Prednisolone and Atorvastatin in Combination with Ascorbic Acid.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Atorvastatin; Diclofenac; Disease Models, Animal; Drug Combinations; Drug Dosage Calculations; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Prednisolone; Rats; Treatment Outcome | 2020 |
ANALGESIC EFFECT OF INTRAVENOUS ASCORBIC ACID VERSUS ACELCOFENAC POST-TRANSALVEOLAR EXTRACTION: A CASE-CONTROL STUDY.
Topics: Administration, Intravenous; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Diclofenac; Double-Blind Method; Edema; Humans; Molar, Third; Pain, Postoperative; Tooth Extraction; Tooth, Impacted | 2019 |