diclofenac has been researched along with arachidonic acid in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (25.00) | 18.7374 |
| 1990's | 12 (25.00) | 18.2507 |
| 2000's | 11 (22.92) | 29.6817 |
| 2010's | 11 (22.92) | 24.3611 |
| 2020's | 2 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Bhatti, R; Kaur, M; Sharma, S; Singh, A; Singh, P | 1 |
| Bendele, AM; Benslay, DN; Hom, JT; Lee, SJ; Lindstrom, TD; Naismith, RW; Ruterbories, KJ; Spaethe, SM | 1 |
| Fernandes, G; Flescher, E; Fossum, D; Gray, PJ; Harper, MJ; Talal, N | 1 |
| Ebeling, L; Loschen, G | 1 |
| Lewis, GP; O'Neill, LA | 1 |
| Kothari, HV; Ku, EC; Lee, WH | 1 |
| Kothari, HV; Ku, EC; Lee, W; Scholer, DW | 1 |
| Boettcher, I; Ku, EC; Scholer, DW; Schweizer, A | 2 |
| Barrett, PA; Butler, KD; Shand, RA; Wallis, RB | 1 |
| Fukui, Y; Hirasawa, N; Ohuchi, K; Ozeki, T; Tsurufuji, S; Watanabe, M | 1 |
| Kimble, EF; Kothari, HV; Ku, EC; Lee, W; Liauw, L; Tjan, J | 1 |
| Kimble, EF; Kothari, H; Ku, EC; Lee, W; Liauw, LH | 1 |
| Aldo-Benson, MA; Benson, MD; Brandt, KD; Chan, K; Ku, E; Lee, W; Liauw, HL; Vyas, K; Waiter, SL | 1 |
| Bhattacharya, SK; Das, N | 1 |
| Baumann, J; von Bruchhausen, F; Wurm, G | 1 |
| Boyer, S; Falk-Filipsson, A; Låstbom, L; Moldéus, P; Ryrfeldt, A | 1 |
| Bauersachs, J; Busse, R; Hecker, M | 1 |
| Koay, P | 1 |
| Forn, J; García-Rafanell, J; Merlos, M; Vericat, ML | 1 |
| Hayashi, S; McDonnell, PJ; Phillips, AF; Seitz, B; Wee, WR | 1 |
| Andĕrova, E; Jandera, A; Kuchar, M; Panajotova, V | 1 |
| Låstbom, L; Moldéus, P; Ryrfeldt, A; Skarping, G | 1 |
| Fisher, MB; Haining, RL; Henne, KR; Jones, JP; Koop, DR; Rettie, AE; Trager, WF | 1 |
| Bouchard, JF; Lamontagne, D | 1 |
| Dannhardt, G; Fiebich, B; Kiefer, W; Krämer, G; Maehrlein, S; Nowe, U | 1 |
| Shoyama, Y; Watanabe, S; Yamaguchi, T; Yamamoto, T | 1 |
| Klein, T; Neuhaus, K; Nüsing, RM; Reutter, F | 1 |
| Anikwue, R; Huffman, JW; Martin, ZL; Welch, SP | 1 |
| Kalgutkar, AS; Kiefer, JR; Kozak, KR; Kurumbail, RG; Marnett, LJ; Pawlitz, JL; Prusakiewicz, JJ; Rowlinson, SW; Stallings, WC | 1 |
| Al-Falaki, O; Blaicher, AM; Gruber, D; Hoerauf, K; Landsteiner, HT; Volf, I; Zimpfer, M; Zwerina, J | 1 |
| Anggadiredja, K; Hiranita, T; Nakamichi, M; Shoyama, Y; Tanaka, H; Watanabe, S; Yamamoto, T | 1 |
| Matsumoto, Y; Watanabe, S; Yamaguchi, T; Yamamoto, T | 1 |
| Munsterhjelm, E; Niemi, TT; Rosenberg, PH; Silvanto, M; Ylikorkala, O | 1 |
| Branson, J; Guillaume, M; Jermany, J; Rordorf, C; Schmouder, R | 1 |
| Heenen, M; Mélot, C; Pirard, D; Vereecken, P | 1 |
| Dong, L; Noon, KR; Sharma, NP; Smith, WL; Yuan, C | 1 |
| Ilatovskaya, DV; Levchenko, V; Mattson, DL; Pavlov, TS; Roman, RJ; Staruschenko, A | 1 |
| Mori, T; Shibasaki, M; Shimizu, N; Suzuki, T | 1 |
| Katara, R; Majumdar, DK | 1 |
| Angioni, C; Felden, L; Ferreiros, N; Geisslinger, G; Lötsch, J; Schreiber, Y; von Hentig, N; Walter, C | 1 |
| Chiranthanut, N; Khonsung, P; Kunanusorn, P; Panthong, A; Pingsusaen, P; Rujjanawate, C | 1 |
| Bakhteeva, VT; Fedorova, EV; Fok, EM; Lavrova, EA; Parnova, RG | 1 |
| Katara, R; Majumdar, DK; Sachdeva, S | 1 |
| Ahmed, SA; Al-Lawati, H; Jamali, F | 1 |
| Barceló, D; López-Doval, JC; Rodríguez-Mozaz, S; Sabater, S; Serra-Compte, A | 1 |
| Gorbach, T; Koiro, O; Kudina, O; Shtrygol, S; Tovchiga, O; Yudkevich, T | 1 |
2 review(s) available for diclofenac and arachidonic acid
| Article | Year |
|---|---|
The emerging roles of topical non-steroidal anti-inflammatory agents in ophthalmology.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Conjunctivitis, Allergic; Diclofenac; Drug Therapy; Edema; Eye Diseases; Humans; Indomethacin; Pain, Postoperative; Postoperative Complications; Pyrazoles | 1996 |
Three percent diclofenac in 2.5% hyaluronan gel in the treatment of actinic keratoses: a meta-analysis of the recent studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Gels; Humans; Hyaluronic Acid; Keratosis | 2005 |
3 trial(s) available for diclofenac and arachidonic acid
| Article | Year |
|---|---|
Acetylsalicylic acid, diclofenac, and lornoxicam, but not rofecoxib, affect platelet CD 62 expression.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Flow Cytometry; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Piroxicam; Platelet Function Tests; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Selectins; Sulfones | 2004 |
Lumiracoxib does not affect the ex vivo antiplatelet aggregation activity of low-dose aspirin in healthy subjects.
Topics: Adolescent; Adult; Arachidonic Acid; Aspirin; Collagen; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Epoprostenol; Female; Humans; Male; Middle Aged; Organic Chemicals; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2 | 2005 |
Similar maximum systemic but not local cyclooxygenase-2 inhibition by 50 mg lumiracoxib and 90 mg etoricoxib: a randomized controlled trial in healthy subjects.
Topics: Adult; Arachidonic Acid; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Humans; Male; Prostaglandins; Pyridines; Sulfones; Young Adult | 2014 |
43 other study(ies) available for diclofenac and arachidonic acid
| Article | Year |
|---|---|
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Rational design, synthesis and evaluation of chromone-indole and chromone-pyrazole based conjugates: identification of a lead for anti-inflammatory drug.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chromones; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Indoles; Mice; Models, Molecular; Molecular Structure; Pain; Pain Measurement; Pyrazoles; Structure-Activity Relationship | 2014 |
Anti-inflammatory activity of BF389, a Di-T-butylphenol, in animal models of arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis, Experimental; Collagen; Diamines; Diclofenac; Dinoprostone; Disease Models, Animal; Female; Interleukin-1; Leukotriene B4; Male; Naproxen; Oxazines; Phenols; Piroxicam; Rats; Rats, Inbred Lew; Thromboxane B2 | 1992 |
Aspirin-like drugs prime human T cells. Modulation of intracellular calcium concentrations.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Differentiation, T-Lymphocyte; Arachidonic Acid; Arachidonic Acids; Calcium; CD8 Antigens; Cell Division; Chromatography, High Pressure Liquid; Diclofenac; Dinoprostone; Drug Synergism; Female; Flow Cytometry; Flurbiprofen; Humans; Indomethacin; Interleukin-2; Lymphocyte Activation; Male; Middle Aged; Phytohemagglutinins; Radioimmunoassay; T-Lymphocytes | 1991 |
[Inhibition of arachidonic acid cascade by extract of rye pollen].
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Diclofenac; Lipoxygenase Inhibitors; Microsomes; Plant Extracts; Pollen; Rats; Secale | 1991 |
Inhibitory effects of diclofenac and indomethacin on interleukin-1-induced changes in PGE2 release. A novel effect on free arachidonic acid levels in human synovial cells.
Topics: Acute-Phase Reaction; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Diclofenac; Dinoprostone; Humans; Indomethacin; Interleukin-1; Synovial Membrane | 1989 |
An alternate mechanism for regulation of leukotriene production in leukocytes: studies with an anti-inflammatory drug, sodium diclofenac.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Biological Availability; Calcimycin; Cell-Free System; Cyclooxygenase Inhibitors; Diclofenac; Guinea Pigs; In Vitro Techniques; Leukocytes; Leukotriene B4; Male; Oleic Acid; Oleic Acids; Rats; Rats, Inbred Strains; SRS-A; Triglycerides | 1987 |
Effect of diclofenac sodium on the arachidonic acid cascade.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Lipoxygenase Inhibitors; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Naproxen; Phospholipids; Piroxicam; Prostaglandins E; Rats; SRS-A; Thiazines; Triglycerides | 1986 |
Pharmacology of diclofenac sodium.
Topics: Analgesics; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Fever; Humans; Inflammation; Lethal Dose 50; Leukocytes; Mice; Pain; Rats | 1986 |
Intrathoracic platelet accumulation in the guinea-pig induced by intravenous administration of arachidonic acid--effect of cyclooxygenase and thromboxane synthetase inhibitors.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Chromium Radioisotopes; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Fibrinogen; Guinea Pigs; Injections, Intravenous; Iodine Radioisotopes; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Pulmonary Circulation; Thorax; Thromboxane B2; Thromboxane-A Synthase | 1986 |
The effect of diphenylamine derivatives on arachidonic acid metabolism in rat peritoneal macrophages.
Topics: Aniline Compounds; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Diclofenac; Dinoprostone; Diphenylamine; Macrophages; Male; Mefenamic Acid; ortho-Aminobenzoates; Peritoneal Cavity; Prostaglandins E; Radioimmunoassay; Rats; Rats, Inbred Strains | 1987 |
The effects of diclofenac sodium on arachidonic acid metabolism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Leukocytes; Lipoxygenase; Naproxen; Phospholipases A; Phospholipases A2; Phospholipids; Piroxicam; Prostaglandins E; SRS-A; Thiazines; Triglycerides | 1985 |
Pharmacology of diclofenac sodium (Voltaren).
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arthritis, Experimental; Cyclooxygenase Inhibitors; Diclofenac; Digestive System; Drug Tolerance; Fever; Humans; Mice; Nociceptors; Rats | 1985 |
Effects of diclofenac sodium on arachidonic acid metabolism.
Topics: Arachidonic Acid; Arachidonic Acids; Diclofenac; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Monocytes; Naproxen; Neutrophils; Piroxicam; SRS-A; Thiazines | 1985 |
Effects of Voltaren on arachidonic acid metabolism in arthritis patients.
Topics: Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Metabolic Clearance Rate; Osteoarthritis; Prostaglandins E; Synovial Fluid; Thromboxane B2 | 1985 |
Effect of central prostaglandins on carrageenan-induced pedal oedema in rats.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Carrageenan; Diclofenac; Dinoprost; Dinoprostone; Edema; Female; Injections, Intraventricular; Male; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats | 1984 |
Decreasing inhibitory potency of prostaglandin synthetase inhibitors during their cooxidative metabolism. Studies on aminophenols, pyrazolon derivatives and 1,3-diphenylisobenzofuran.
Topics: Acetaminophen; Aminophenols; Aminopyrine; Animals; Arachidonic Acid; Arachidonic Acids; Benzofurans; Cyclooxygenase Inhibitors; Diclofenac; Indomethacin; Kidney Medulla; Lipoxygenase Inhibitors; Male; Peroxides; Phenacetin; Phenylbutazone; Rats; Rats, Inbred Strains | 1983 |
Mechanisms of 3-carene-induced bronchoconstriction in the isolated guinea pig lung.
Topics: Animals; Arachidonic Acid; Bicyclic Monoterpenes; Bronchoconstriction; Carbazoles; Cattle; Cells, Cultured; Diclofenac; Dose-Response Relationship, Drug; Endothelium; Guinea Pigs; In Vitro Techniques; Lung; Male; Monoterpenes; Prostaglandin Antagonists; Pulmonary Artery; Respiratory Mechanics; Terpenes; Thromboxane B2; Time Factors | 1995 |
Display of the characteristics of endothelium-derived hyperpolarizing factor by a cytochrome P450-derived arachidonic acid metabolite in the coronary microcirculation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arginine; Biological Factors; Bradykinin; Calcium Channel Blockers; Capillaries; Coronary Vessels; Cytochrome P-450 Enzyme System; Diclofenac; Epoprostenol; Female; In Vitro Techniques; Male; Nitric Oxide; Nitroarginine; Nitroprusside; Prostaglandin Endoperoxides, Synthetic; Quinacrine; Rats; Rats, Wistar; Thromboxane A2; Vasoconstrictor Agents; Vasodilation | 1994 |
Topical anti-inflammatory properties of flutrimazole, a new imidazole antifungal agent.
Topics: Administration, Topical; Animals; Anthralin; Anti-Inflammatory Agents; Antifungal Agents; Arachidonic Acid; Carrageenan; Clotrimazole; Cyclooxygenase Inhibitors; Diclofenac; Edema; Granulocytes; Humans; Ketoconazole; Leukotriene B4; Male; Mice; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
Effect of diclofenac, ketorolac, and fluorometholone on arachidonic acid metabolites following excimer laser corneal surgery.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Chemotaxis, Leukocyte; Cornea; Diclofenac; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Fluorometholone; Ketorolac; Lasers, Excimer; Leukotriene B4; Neutrophils; Ophthalmic Solutions; Photorefractive Keratectomy; Rabbits; Tolmetin | 1996 |
Pharmacological profile of the novel potent antirheumatic 4-(2',4'-difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic acid.
Topics: Abdominal Pain; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis, Experimental; Butyrates; Carrageenan; Diclofenac; Dinoprostone; Edema; Female; Graft vs Host Reaction; Leukotriene B4; Male; Mice; Mice, Inbred C57BL; Phagocytosis; Phenylbutyrates; Pleurisy; Rats; Rats, Inbred Lew; Stomach Ulcer | 1997 |
Hexamethylene diisocyanate (HDI)-induced lung impairment: studies in isolated perfused and ventilated guinea pig lungs.
Topics: Animals; Arachidonic Acid; Bronchoconstriction; Cyanates; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Isocyanates; Lung; Lung Compliance; Male; Perfusion; Pulmonary Circulation; Pulmonary Ventilation; Thromboxanes | 1997 |
Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding.
Topics: Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Binding Sites; Blotting, Western; Catalysis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Kinetics; Lauric Acids; Leucine; Mutagenesis, Site-Directed; Phenylalanine; Protein Structure, Secondary; Static Electricity; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Sulfaphenazole; Warfarin | 1999 |
Mechanisms of protection afforded by cyclooxygenase inhibitors to endothelial function against ischemic injury in rat isolated hearts.
Topics: Animals; Arachidonic Acid; Cardiotonic Agents; Coronary Circulation; Coronary Vessels; Cyclooxygenase Inhibitors; Diclofenac; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Indomethacin; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Random Allocation; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1999 |
The pyrrole moiety as a template for COX-1/COX-2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Humans; Indomethacin; Isoenzymes; Leukocytes, Mononuclear; Membrane Proteins; Molecular Structure; Monocytes; Neutrophils; Prostaglandin-Endoperoxide Synthases; Pyrroles; Sulfones; Thiophenes | 2000 |
Behavioral suppression induced by cannabinoids is due to activation of the arachidonic acid cascade in rats.
Topics: Animals; Arachidonic Acid; Behavior, Animal; Cannabinoids; Conditioning, Operant; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Dronabinol; Hallucinogens; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Second Messenger Systems | 2001 |
Generation of 8-epi-prostaglandin F(2alpha) in isolated rat kidney glomeruli by a radical-independent mechanism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arachidonic Acid; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Diclofenac; Dinoprost; Dose-Response Relationship, Drug; Epoprostenol; Esters; F2-Isoprostanes; Female; Free Radicals; In Vitro Techniques; Isoenzymes; Kidney Glomerulus; Male; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Sulfonamides; Thromboxane-A Synthase | 2001 |
Decrease in efficacy and potency of nonsteroidal anti-inflammatory drugs by chronic delta(9)-tetrahydrocannabinol administration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Camphanes; Diclofenac; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Ethanolamines; Indomethacin; Kinetics; Male; Mice; Mice, Inbred ICR; Pain; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug | 2002 |
A novel mechanism of cyclooxygenase-2 inhibition involving interactions with Ser-530 and Tyr-385.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arginine; Binding, Competitive; Cell Line; Crystallography, X-Ray; Cyclooxygenase 2; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Insecta; Isoenzymes; Mice; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Piroxicam; Prostaglandin-Endoperoxide Synthases; Protein Binding; Serine; Sulfonamides; Time Factors; Tyrosine | 2003 |
Endocannabinoid system modulates relapse to methamphetamine seeking: possible mediation by the arachidonic acid cascade.
Topics: Amphetamine-Related Disorders; Animals; Arachidonic Acid; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Central Nervous System Stimulants; Cues; Cyclooxygenase Inhibitors; Diclofenac; Dronabinol; Endocannabinoids; Extinction, Psychological; Male; Methamphetamine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Rimonabant; Secondary Prevention; Self Administration | 2004 |
Involvement of arachidonic acid cascade in working memory impairment induced by interleukin-1 beta.
Topics: Animals; Arachidonic Acid; Diclofenac; Hippocampus; Interleukin-1; Male; Memory Disorders; Rats; Rats, Wistar; Signal Transduction | 2004 |
Characterization of inhibition of platelet function by paracetamol and its interaction with diclofenac in vitro.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandin-Endoperoxide Synthases; Thromboxane B2 | 2005 |
Asymmetric acetylation of the cyclooxygenase-2 homodimer by aspirin and its effects on the oxygenation of arachidonic, eicosapentaenoic, and docosahexaenoic acids.
Topics: Acetylation; Arachidonic Acid; Aspirin; Base Sequence; Chromatography, Liquid; Chromatography, Thin Layer; Cyclooxygenase 2; Diclofenac; Dimerization; DNA Primers; Docosahexaenoic Acids; Eicosapentaenoic Acid; Humans; Mutagenesis; Oxygen; Tandem Mass Spectrometry | 2010 |
Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC).
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Cell Line; CHO Cells; Cricetinae; Cricetulus; Cytochrome P-450 Enzyme System; Diclofenac; Epithelial Sodium Channels; Female; Ibuprofen; Kidney Tubules, Collecting; Mice; Models, Animal; Ovary; Patch-Clamp Techniques; Transfection | 2011 |
Involvement of the arachidonic acid cascade in the hypersusceptibility to pentylenetetrazole-induced seizure during diazepam withdrawal.
Topics: Animals; Arachidonic Acid; Convulsants; Cyclooxygenase Inhibitors; Diazepam; Diclofenac; Enzyme Inhibitors; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Mice; Mice, Inbred Strains; Pentylenetetrazole; Phospholipase A2 Inhibitors; Prostaglandin-Endoperoxide Synthases; Psychotropic Drugs; Quinacrine; Seizures; Substance Withdrawal Syndrome | 2012 |
Eudragit RL 100-based nanoparticulate system of aceclofenac for ocular delivery.
Topics: Acrylic Resins; Administration, Ophthalmic; Animals; Arachidonic Acid; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cornea; Diclofenac; Drug Delivery Systems; Drug Stability; Eye; Goats; Inflammation; Nanoparticles; Particle Size; Permeability; Polymers; Rabbits; Solutions; Spectroscopy, Fourier Transform Infrared; Static Electricity; Surface Properties; Suspensions; X-Ray Diffraction | 2013 |
Investigation of anti-inflammatory, antinociceptive and antipyretic activities of Stahlianthus involucratus rhizome ethanol extract.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Arachidonic Acid; Carrageenan; Diclofenac; Edema; Ethanol; Granuloma; Male; Mice; Phenylpropionates; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Zingiberaceae | 2015 |
[Deposition of exogenous and endogenously generated unsaturated fatty acids in lipid droplets triacylglycerol as a mechanism of its sequestration in epithelial cells].
Topics: Animals; Arachidonic Acid; Biological Transport; Carnitine O-Palmitoyltransferase; Cholesterol Esters; Cyclooxygenase 1; Cyclooxygenase 2; Diclofenac; Dinoprostone; Enzyme Inhibitors; Epithelial Cells; Epoxy Compounds; Lipid Droplets; Lipid Metabolism; Oleic Acid; Primary Cell Culture; Rana temporaria; Triglycerides; Tritium; Urinary Bladder; Urothelium | 2014 |
Enhancement of ocular efficacy of aceclofenac using biodegradable PLGA nanoparticles: formulation and characterization.
Topics: Administration, Ophthalmic; Animals; Arachidonic Acid; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Diclofenac; Disease Models, Animal; Drug Liberation; Eye Diseases; Lactic Acid; Nanoparticles; Particle Size; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; X-Ray Diffraction | 2017 |
Dose-dependency of the cardiovascular risks of non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis, Experimental; Cardiovascular Diseases; Diclofenac; Hydroxyeicosatetraenoic Acids; Male; Rats; Rats, Sprague-Dawley; Risk Factors | 2019 |
Diet quality and NSAIDs promote changes in formation of prostaglandins by an aquatic invertebrate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Diclofenac; Diet; Ibuprofen; Invertebrates; Ketoprofen; Lipid Metabolism; Naproxen; Prostaglandins | 2020 |
The effect of non-steroidal anti-inflammatory drugs with different mechanisms of action on the body temperature and cyclooxygenase pathway of the arachidonic acid cascade on the model of acute general cooling (air hypothermia) in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Body Temperature; Cyclooxygenase 2; Diclofenac; Dinoprost; Dinoprostone; Etoricoxib; Hypothermia; Rats | 2022 |