diclofenac and 6-ketoprostaglandin f1 alpha

diclofenac has been researched along with 6-ketoprostaglandin f1 alpha in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19907 (24.14)18.7374
1990's11 (37.93)18.2507
2000's10 (34.48)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bassenge, E; Busse, R; König, A; Lamontagne, D1
Abe, K; Akiu, N; Saito, T; Sato, M; Takeuchi, K; Yasujima, M; Yoshinaga, K1
Kothari, HV; Ku, EC; Lee, W; Scholer, DW1
Butler, KD; Shand, RA; Wallis, RB1
Korttila, K; Valanne, J; Ylikorkala, O1
Ali, M; Angelo-Khattar, M; Thulesius, O1
Isomäki, H; Laitinen, O; Nissilä, M; Nuotio, P; Nykänen, E; Seppälä, E; Vapaatalo, H1
Arakawa, T; Fukuda, T; Kobayashi, K; Nakamura, H; Satoh, H1
Kimble, EF; Kothari, HV; Ku, EC; Lee, W; Liauw, L; Tjan, J1
Blower, P; Melarange, R; Spangler, R1
Willburger, RE; Wittenberg, RH1
Church, DJ; Lang, U; Vallotton, MB; Van der Bent, V1
Franco-Cereceda, A; Källner, G; Lundberg, JM1
Busse, R; Fleming, I; Popp, R1
Hamilton, LC; Warner, TD1
Janzen, R; Koch, T; Münter, K; Neuhof, H; Schmeck, J1
Andrieu, S; Berdeaux, A; Bévérelli, F; Giudicelli, JF; Lebret, M; Maclouf, J1
Arvola, P; Kähönen, M; Kainulainen, H; Mäkynen, H; Mucha, I; Pörsti, I; Riutta, A; Solakivi, T; Wu, X1
Geisslinger, G; Gühring, H; Neupert, W; Tegeder, I1
Edwards, SR; Grace, RF; Lin, Y; Mather, LE; Power, I1
Giuliano, F; Mitchell, JA; Warner, TD1
Hattori, T; Itoh, T; Kajikuri, J; Katsuya, H1
Cmiel, A; Mejza, F; Szczeklik, A; Tuleja, E1
Abacioglu, N; Altug, S; Demirkay, B; Tunçtan, B; Uludag, O1
Ayoub, SS; Botting, RM; Colville-Nash, PR; Willoughby, DA1
Benyó, Z; Hortobágyi, L; Horváth, B; Hrabák, A; Lenzsér, G; Sándor, P; Schweer, H1
Lindahl, SG; Nyren, S; Rimeika, D; Sanchez-Crespo, A; Wiklund, CU1
Buerkle, MA; Hellwig, N; Klauss, V; Krötz, F; Mannell, H; Pircher, J; Pohl, U; Sohn, HY; Struthmann, L1
Bjerring, PN; Larsen, FS; Pedersen, HR; Rohde, J1

Trials

2 trial(s) available for diclofenac and 6-ketoprostaglandin f1 alpha

ArticleYear
Intravenous diclofenac sodium decreases prostaglandin synthesis and postoperative symptoms after general anaesthesia in outpatients undergoing dental surgery.
    Acta anaesthesiologica Scandinavica, 1987, Volume: 31, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Diclofenac; Double-Blind Method; Epoprostenol; Female; Humans; Injections, Intravenous; Isoflurane; Male; Oral Hemorrhage; Pain, Postoperative; Random Allocation; Thromboxane A2

1987
Effects of cyclooxygenases inhibitors on vasoactive prostanoids and thrombin generation at the site of microvascular injury in healthy men.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Jun-01, Volume: 23, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Endothelium, Vascular; Fibrinolytic Agents; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Naproxen; Prostaglandin-Endoperoxide Synthases; Sulfones; Thrombin; Thromboxane B2

2003

Other Studies

27 other study(ies) available for diclofenac and 6-ketoprostaglandin f1 alpha

ArticleYear
Prostacyclin and nitric oxide contribute to the vasodilator action of acetylcholine and bradykinin in the intact rabbit coronary bed.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Animals; Arginine; Bradykinin; Coronary Circulation; Cyclic AMP; Cyclooxygenase Inhibitors; Diclofenac; Epoprostenol; Female; In Vitro Techniques; Male; Nitric Oxide; Nitroarginine; Rabbits; Vasodilation

1992
Effect of sulindac on prostaglandin synthesis in human and in cultured rat renal and vascular smooth muscle cells.
    The Tohoku journal of experimental medicine, 1992, Volume: 166, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Animals; Arachidonic Acids; Cells, Cultured; Creatinine; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Kidney; Kidney Glomerulus; Male; Middle Aged; Muscle, Smooth, Vascular; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulindac

1992
Effect of diclofenac sodium on the arachidonic acid cascade.
    The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Lipoxygenase Inhibitors; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Naproxen; Phospholipids; Piroxicam; Prostaglandins E; Rats; SRS-A; Thiazines; Triglycerides

1986
The effects of modulation of prostanoid metabolism on the thoracic platelet accumulation induced by intravenous administration of collagen in the guinea-pig.
    Thrombosis and haemostasis, 1986, Dec-15, Volume: 56, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Chromium Radioisotopes; Collagen; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Injections, Intravenous; Platelet Aggregation; Platelet Count; Prostaglandins; Pyridines; Thorax; Thromboxane B2; Thromboxanes

1986
The effect of prostaglandin synthesis inhibition on motility of the sheep ureter.
    Acta physiologica Scandinavica, 1987, Volume: 131, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Diclofenac; Dinoprost; Humans; Indomethacin; Muscle Contraction; Muscle, Smooth; Prostaglandins F; Sheep; Thromboxane B2; Ureter

1987
Comparison of the effects of different anti-inflammatory drugs on synovial fluid prostanoid concentrations in patients with rheumatoid arthritis.
    Clinical rheumatology, 1985, Volume: 4, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Dinoprostone; Guanidines; Humans; Indomethacin; Naproxen; ortho-Aminobenzoates; Prednisolone; Prostaglandins; Prostaglandins E; Quinazolines; Synovial Fluid; Thromboxane B2

1985
Effect of indomethacin, tiaprofenic acid and dicrofenac on rat gastric mucosal damage and content of prostacyclin and prostaglandin E2.
    Prostaglandins, 1985, Volume: 30, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Gastric Fundus; Gastric Mucosa; Indomethacin; Male; Propionates; Prostaglandins E; Radioimmunoassay; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1985
The effects of diclofenac sodium on arachidonic acid metabolism.
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2 Suppl 1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Leukocytes; Lipoxygenase; Naproxen; Phospholipases A; Phospholipases A2; Phospholipids; Piroxicam; Prostaglandins E; SRS-A; Thiazines; Triglycerides

1985
Comparison of the anti-inflammatory activity and gastrointestinal irritancy of nabumetone, ibuprofen, and diclofenac in rats following chronic administration.
    European journal of rheumatology and inflammation, 1994, Volume: 14, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Carrageenan; Cecum; Diclofenac; Digestive System; Drug Administration Schedule; Gastric Mucosa; Gastrointestinal Diseases; Haptoglobins; Hemoglobins; Ibuprofen; Ileum; Male; Nabumetone; Rats; Rats, Wistar

1994
Prostaglandin release from lumbar disc and facet joint tissue.
    Spine, 1994, Sep-15, Volume: 19, Issue:18

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Cartilage, Articular; Diclofenac; Dinoprostone; Humans; In Vitro Techniques; Indomethacin; Intervertebral Disc; Leukotriene C4; Lumbar Vertebrae; Radioimmunoassay

1994
Role of prostaglandin-mediated cyclic AMP formation in protein kinase C-dependent secretion of atrial natriuretic peptide in rat cardiomyocytes.
    The Biochemical journal, 1994, Oct-01, Volume: 303 ( Pt 1)

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Atrial Natriuretic Factor; Bucladesine; Cells, Cultured; Cyclic AMP; Diclofenac; Dinoprost; Dinoprostone; Epoprostenol; Heart; Heart Ventricles; Indomethacin; Kinetics; Myocardial Contraction; Myocardium; Nifedipine; Prostaglandins; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thionucleotides

1994
Cyclo-oxygenase products released by low pH have capsaicin-like actions on sensory nerves in the isolated guinea pig heart.
    Cardiovascular research, 1994, Volume: 28, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Diclofenac; Epoprostenol; Guinea Pigs; Heart; Hydrogen-Ion Concentration; Indomethacin; Lactates; Lactic Acid; Neurons, Afferent; Perfusion; Receptors, Drug

1994
Pulsatile stretch in coronary arteries elicits release of endothelium-derived hyperpolarizing factor: a modulator of arterial compliance.
    Circulation research, 1998, Apr-06, Volume: 82, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Apamin; Biological Factors; Cells, Cultured; Coronary Vessels; Diclofenac; Electric Stimulation; Endothelium, Vascular; Fatty Acids, Unsaturated; In Vitro Techniques; Muscle, Smooth, Vascular; Nitroarginine; Oscillometry; Patch-Clamp Techniques; Peptides; Rats; Stress, Mechanical; Swine; Vasodilation

1998
Interactions between inducible isoforms of nitric oxide synthase and cyclo-oxygenase in vivo: investigations using the selective inhibitors, 1400W and celecoxib.
    British journal of pharmacology, 1998, Volume: 125, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Amidines; Analysis of Variance; Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylamines; Celecoxib; Crotonates; Cyclooxygenase 2; Dexamethasone; Diclofenac; Enzyme Inhibitors; Hydroxybutyrates; Isoenzymes; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitriles; Nitrites; Nitrogen Dioxide; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Toluidines

1998
Endothelin-1 and thromboxane A2 increase pulmonary vascular resistance in granulocyte-mediated lung injury.
    Critical care medicine, 1998, Volume: 26, Issue:11

    Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Female; Granulocytes; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Perfusion; Phenylpropionates; Prospective Studies; Pulmonary Artery; Pyrimidines; Rabbits; Random Allocation; Respiratory Distress Syndrome; Thromboxane A2; Thromboxane B2; Vascular Resistance

1998
Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bradykinin; Coronary Disease; Coronary Vessels; Cyclooxygenase Inhibitors; Diclofenac; Dogs; Dose-Response Relationship, Drug; Hyperemia; Male; Myocardium; Nitric Oxide Synthase; Nitroarginine; Salicylic Acid; Thromboxane B2; Time Factors

1999
Exercise enhances vasorelaxation in experimental obesity associated hypertension.
    Cardiovascular research, 1999, Volume: 43, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Analysis of Variance; Animals; Blood Glucose; Carotid Arteries; Cholesterol; Cyclooxygenase Inhibitors; Diclofenac; Endothelium, Vascular; Hypertension; In Vitro Techniques; Insulin; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Obesity; Physical Exertion; Rats; Rats, Zucker; Thromboxane B2; Triglycerides; Vasodilation; Vasodilator Agents

1999
Effects of selective and unselective cyclooxygenase inhibitors on prostanoid release from various rat organs.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dose-Response Relationship, Drug; Ketorolac; Kidney; Lung; Male; Meloxicam; Nitrobenzenes; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiazines; Thiazoles; Thromboxane B2

2000
Effects of diclofenac in the rat tail ischaemia--reperfusion injury model of acute hyperalgesia.
    Pain, 2001, Volume: 89, Issue:2-3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Brain Chemistry; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Hyperalgesia; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury; Tail; Thromboxane B2

2001
Sodium salicylate inhibits prostaglandin formation without affecting the induction of cyclooxygenase-2 by bacterial lipopolysaccharide in vivo.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blotting, Western; Cardiovascular System; Cholinesterase Inhibitors; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Enzyme Induction; Isoenzymes; Isoflurophate; Lipopolysaccharides; Male; Nitrates; Nitrites; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Sodium Salicylate

2001
Effects of H2O2 on membrane potential of smooth muscle cells in rabbit mesenteric resistance artery.
    European journal of pharmacology, 2003, Mar-19, Volume: 464, Issue:2-3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzoquinones; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Hydrogen Peroxide; In Vitro Techniques; Leukotriene C4; Leukotriene D4; Lipoxygenase Inhibitors; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channel Blockers; Rabbits; Vasodilator Agents

2003
Effects of cyclooxygenase inhibitors on nitric oxide production and survival in a mice model of sepsis.
    Pharmacological research, 2003, Volume: 48, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Female; Furans; Lipopolysaccharides; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Quinazolines; Sepsis; Sulfonamides

2003
The involvement of a cyclooxygenase 1 gene-derived protein in the antinociceptive action of paracetamol in mice.
    European journal of pharmacology, 2006, May-24, Volume: 538, Issue:1-3

    Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Aminopyrine; Analgesics, Non-Narcotic; Animals; Antipyrine; Behavior, Animal; Blotting, Western; Brain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Spinal Cord

2006
Carbon monoxide-prostaglandin E2 interaction in the hypothalamic circulation.
    Neuroreport, 2008, Oct-29, Volume: 19, Issue:16

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Gas Analysis; Blood Pressure; Carbon Monoxide; Cyclooxygenase Inhibitors; Deuteroporphyrins; Diclofenac; Dinoprost; Dinoprostone; Enzyme Inhibitors; Heart Rate; Heme Oxygenase (Decyclizing); Hypothalamus; Injections, Intraperitoneal; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar

2008
Iloprost inhalation redistributes pulmonary perfusion and decreases arterial oxygenation in healthy volunteers.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:9

    Topics: 6-Ketoprostaglandin F1 alpha; Administration, Inhalation; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Iloprost; Image Processing, Computer-Assisted; Lung; Male; Oxygen; Oxygen Consumption; Posture; Pulmonary Circulation; Pulmonary Gas Exchange; Respiratory Mechanics; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

2009
Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo.
    Journal of thrombosis and haemostasis : JTH, 2009, Volume: 7, Issue:10

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Cells, Cultured; Chlorides; Cricetinae; Cyclooxygenase Inhibitors; Diclofenac; Endothelium, Vascular; Ferric Compounds; Humans; Mesocricetus; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Platelet Activation; Platelet Adhesiveness; Skin Window Technique; Thromboplastin; Thrombosis; Thromboxane B2; Tumor Necrosis Factor-alpha

2009
Effects of dexamethasone and cox inhibitors on intracranial pressure and cerebral perfusion in the lipopolysaccharide treated rats with hyperammonemia.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Ammonium Compounds; Animals; Blood Gas Analysis; Blood Pressure; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Dexamethasone; Diclofenac; Hemodynamics; Hyperammonemia; Indomethacin; Intracranial Pressure; Lipopolysaccharides; Male; Rats; Regional Blood Flow; Time Factors; Tumor Necrosis Factor-alpha

2015