dichlorphenamide and acetazolamide

dichlorphenamide has been researched along with acetazolamide in 180 studies

Research

Studies (180)

TimeframeStudies, this research(%)All Research%
pre-199053 (29.44)18.7374
1990's1 (0.56)18.2507
2000's77 (42.78)29.6817
2010's48 (26.67)24.3611
2020's1 (0.56)2.80

Authors

AuthorsStudies
Anderson, PS; Baldwin, JJ; Best, DB; Christy, ME; Freedman, MB; Gautheron, P; Graham, SL; Habecker, CN; Hoffman, JM; Shepard, KL1
Bicking, JB; Brown, SL; deSolms, SJ; Fishman, DR; Gautheron, PD; Graham, SL; Hoffman, JM; Larson, RD; Schwam, H; Woltersdorf, OW1
Briganti, F; Menabuoni, L; Mincione, F; Mincione, G; Scozzafava, A; Supuran, CT1
Casini, A; Ilies, MA; Menabuoni, L; Mincione, F; Scozzafava, A; Supuran, CT1
Menabuoni, L; Mincione, F; Scozzafava, A; Supuran, CT1
Scozzafava, A; Supuran, CT2
Grüneberg, S; Klebe, G; Stubbs, MT1
Casini, A; Montero, JL; Scozzafava, A; Supuran, CT; Winum, JY1
Abbate, F; Antel, J; Casini, A; David, S; Schäfer, S; Scozzafava, A; Supuran, CT; Waldeck, H1
Franchi, M; Gallori, E; Pastorek, J; Pastorekova, S; Scozzafava, A; Supuran, CT; Vullo, D1
Caproiu, MT; Ilies, M; Ilies, MA; Pastorek, J; Pastorekova, S; Scozzafava, A; Supuran, CT; Vullo, D1
Casini, A; Mincione, F; Montero, JL; Scozzafava, A; Starnotti, M; Supuran, CT; Winum, JY1
Abbate, F; Casini, A; Ciattini, S; Coetzee, A; Scozzafava, A; Supuran, CT1
Casini, A; Heine, A; Klebe, G; Kuhn, D; Scozzafava, A; Supuran, CT; Weber, A1
Antel, J; Franchi, M; Gallori, E; Scozzafava, A; Supuran, CT; Vullo, D1
Casini, A; Pastorek, J; Pastorekova, S; Scozzafava, A; Supuran, CT; Vullo, D1
Pastorek, J; Pastorekova, S; Scozzafava, A; Supuran, CT; Vullo, D1
Casey, JR; Mastrolorenzo, A; Morgan, PE; Scozzafava, A; Supuran, CT; Vullo, D1
Casini, A; de Leval, X; Dogné, JM; Ilies, M; Masini, E; Mincione, F; Scozzafava, A; Starnotti, M; Supuran, CT1
Jaiswal, M; Khadikar, PV; Scozzafava, A; Supuran, CT1
Casini, A; Lehtonen, JM; Parkkila, S; Scozzafava, A; Supuran, CT; Vullo, D1
Fasolis, G; Garaj, V; Innocenti, A; Montero, JL; Puccetti, L; Scozzafava, A; Supuran, CT; Vullo, D; Winum, JY2
Alcaro, MC; Casini, A; Innocenti, A; Papini, AM; Scozzafava, A; Supuran, CT1
Cecchi, A; Innocenti, A; Montero, JL; Scozzafava, A; Supuran, CT; Vullo, D; Winum, JY1
Casini, A; Ferry, JG; Innocenti, A; Scozzafava, A; Supuran, CT; Zimmerman, S1
Durgun, M; Emul, M; Innocenti, A; Scozzafava, A; Supuran, CT; Turkmen, H; Vullo, D; Yilmaztekin, S1
Innocenti, A; Jakubickova, L; Montero, JL; Pastorek, J; Pastorekova, S; Scozzafava, A; Supuran, CT; Vullo, D; Winum, JY1
Innocenti, A; Nishimori, I; Pastorek, J; Pastoreková, S; Scozzafava, A; Supuran, CT; Vullo, D1
Innocenti, A; Kaila, K; Ranki, H; Rivera, C; Scozzafava, A; Supuran, CT; Voipio, J; Vullo, D1
Antel, J; Firnges, MA; Innocenti, A; Scozzafava, A; Supuran, CT; Wurl, M1
Casini, A; de Leval, X; Dogné, JM; Innocenti, A; Montero, JL; Scozzafava, A; Supuran, CT; Vullo, D; Winum, JY1
Cecchi, A; Fasolis, G; Gamberi, A; Montero, JL; Puccetti, L; Scozzafava, A; Supuran, CT; Winum, JY1
Chohan, ZH; Fasolis, G; Puccetti, L; Scozzafava, A; Supuran, CT; Vullo, D1
Cecchi, A; Hulikova, A; Montero, JL; Pastorek, J; Pastoreková, S; Scozzafava, A; Supuran, CT; Winum, JY1
Innocenti, A; Mastrolorenzo, A; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D2
Bacciottini, L; Casini, A; Masini, E; Mincione, F; Scozzafava, A; Scrivanti, C; Starnotti, M; Supuran, CT; Vullo, D1
Gil, MJ; Innocenti, A; Martinez-Merino, V; Scozzafava, A; Supuran, CT; Villar, R; Vullo, D1
D'Ambrosio, K; De Simone, G; Di Fiore, A; Pedone, C; Scozzafava, A; Supuran, CT1
Minakuchi, T; Morimoto, K; Nishimori, I; Onishi, S; Scozzafava, A; Supuran, CT; Vullo, D1
Minakuchi, T; Morimoto, K; Nishimori, I; Onishi, S; Sano, S; Scozzafava, A; Supuran, CT; Takeuchi, H; Vullo, D1
Brzozowski, Z; Innocenti, A; Kornicka, A; Pomarnacka, E; Saczewski, F; Scozzafava, A; Supuran, CT; Sławiński, J1
De Simone, G; Di Fiore, A; Montero, JL; Pedone, C; Scozzafava, A; Supuran, CT; Vitale, RM; Winum, JY1
Bornaghi, LF; Houston, TA; Innocenti, A; Poulsen, SA; Supuran, CT; Wilkinson, BL1
Ciattini, S; El Cheikh, K; Innocenti, A; Montero, JL; Scozzafava, A; Supuran, CT; Temperini, C; Vullo, D; Winum, JY1
Bornaghi, LF; Houston, TA; Innocenti, A; Poulsen, SA; Supuran, CT; Vullo, D; Wilkinson, BL2
Minakuchi, T; Nishimori, I; Onishi, S; Scozzafava, A; Supuran, CT; Vullo, D1
Innocenti, A; Marques, S; Santos, MA; Scozzafava, A; Supuran, CT; Vullo, D1
Innocenti, A; Nencetti, S; Nuti, E; Orlandini, E; Rossello, A; Scozzafava, A; Supuran, CT1
Kohsaki, T; Minakuchi, T; Nishimori, I; Onishi, S; Scozzafava, A; Supuran, CT; Takeuchi, H; Vullo, D1
Alterio, V; De Simone, G; Monti, SM; Scozzafava, A; Supuran, CT1
Montero, JL; Regainia, Z; Scozzafava, A; Smaine, FZ; Supuran, CT; Vullo, D; Winum, JY1
Innocenti, A; Poulsen, SA; Salmon, AJ; Supuran, CT; Vullo, D; Williams, ML1
Cecchi, A; Minakuchi, T; Nishimori, I; Onishi, S; Scozzafava, A; Supuran, CT; Vullo, D1
Brzozowski, Z; Innocenti, A; Kornicka, A; Pomarnacka, E; Saczewski, F; Scozzafava, A; Supuran, CT; Sławiński, J; Temperini, C1
Innocenti, A; Poulsen, SA; Supuran, CT; Vullo, D; Wilkinson, BL1
Antel, J; De Simone, G; Di Fiore, A; Pedone, C; Scozzafava, A; Supuran, CT; Waldeck, H; Witte, A; Wurl, M1
Cecchi, A; Scozzafava, A; Supuran, CT; Temperini, C1
D'Ambrosio, K; De Simone, G; Dogné, JM; Innocenti, A; Masereel, B; Scozzafava, A; Supuran, CT; Vitale, RM1
Cecchi, A; Ciani, L; Montero, JL; Ristori, S; Scozzafava, A; Supuran, CT; Winum, JY1
Badawi, AM; Cecchi, A; Morsy, SM; Scozzafava, A; Supuran, CT1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Arslan, O; Aydin, M; Guler, OO; Innocenti, A; Isik, S; Kockar, F; Scozzafava, A; Supuran, CT1
Hilvo, M; Innocenti, A; Kulomaa, MS; Parkkila, S; Salzano, AM; Scaloni, A; Scozzafava, A; Supuran, CT1
Eroğlu, E; Oltulu, O; Yaşar, MM1
Minakuchi, T; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D2
Innocenti, A; Minakuchi, T; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D1
Hall, RA; Innocenti, A; Mühlschlegel, FA; Scozzafava, A; Supuran, CT; Winum, JY1
Balaban, AT; Güzel, O; Maresca, A; Salman, A; Scozzafava, A; Supuran, CT1
Hall, RA; Innocenti, A; Mühlschlegel, FA; Schlicker, C; Scozzafava, A; Steegborn, C; Supuran, CT1
Bertucci, A; Innocenti, A; Scozzafava, A; Supuran, CT; Tambutté, S; Zoccola, D2
Carta, F; Maresca, A; Pothen, B; Singh, V; Supuran, CT; Tiwari, M1
Carta, F; Covarrubias, AS; Jones, TA; Maresca, A; Mowbray, SL; Supuran, CT1
Joseph, P; Köhler, S; Minakuchi, T; Montero, JL; Nishimori, I; Ouahrani-Bettache, S; Scozzafava, A; Supuran, CT; Turtaut, F; Vullo, D; Winum, JY1
Brzozowski, Z; Innocenti, A; Saczewski, F; Supuran, CT; Sławiński, J1
Brzozowski, Z; Innocenti, A; Supuran, CT; Sławiński, J1
Carta, F; Innocenti, A; Kaila, K; Scozzafava, A; Supuran, CT; Temperini, C1
Joseph, P; Köhler, S; Minakuchi, T; Montero, JL; Nishimori, I; Ouahrani-Bettache, S; Scozzafava, A; Supuran, CT; Vullo, D; Winum, JY1
Maresca, A; Supuran, CT1
Cincinelli, A; Innocenti, A; Martellini, T; Scozzafava, A; Supuran, CT1
Maresca, A; Montero, JL; Rami, M; Scozzafava, A; Smaine, FZ; Supuran, CT; Winum, JY1
Avvaru, BS; Carta, F; Garaj, V; Maresca, A; McKenna, R; Robbins, AH; Scozzafava, A; Supuran, CT; Wagner, J1
Benedini, F; Biondi, S; Cecchi, A; Formicola, G; Masini, E; Mincione, F; Pacileo, I; Scozzafava, A; Supuran, CT; Temperini, C1
Aggarwal, M; Biswas, S; Güzel, Ö; McKenna, R; Scozzafava, A; Supuran, CT1
Brzozowski, Z; Gdaniec, M; Innocenti, A; Supuran, CT; Sławiński, J1
Innocenti, A; Knaus, EE; Scozzafava, A; Supuran, CT1
Jackson, DJ; Ohradanova, A; Pastorek, J; Pastorekova, S; Supuran, CT; Vullo, D; Wörheide, G1
Hewitson, KS; Mastrolorenzo, A; Scozzafava, A; Supuran, CT; Vullo, D1
Carta, F; D'Ambrosio, K; De Simone, G; Smaine, FZ; Supuran, CT; Winum, JY1
Capasso, C; Carginale, V; Luca, VD; Rossi, M; Scozzafava, A; Supuran, CT; Vullo, D1
Brzozowski, Z; Supuran, CT; Sławiński, J; Vullo, D1
Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Isik, S; Scozzafava, A; Supuran, CT; Vullo, D1
Capaci Rodrigues, G; Capasso, C; Pan, P; Parkkila, S; Scozzafava, A; Supuran, CT; Tolvanen, ME; Vermelho, AB1
Capasso, C; Leewattanapasuk, W; Mastrolorenzo, A; Mühlschlegel, FA; Supuran, CT; Vullo, D1
Capasso, C; Corte-Real, S; Pan, P; Parkkila, S; Rodrigues, Ide A; Salonen, T; Supuran, CT; Syrjänen, L; Vermelho, AB; Vullo, D1
Chimirri, A; Damiano, FM; De Luca, L; Ferro, S; Gitto, R; Supuran, CT; Vullo, D1
Chojnacki, J; Pogorzelska, A; Supuran, CT; Sławiński, J; Vullo, D; Żołnowska, B1
Alothman, Z; Capasso, C; De Luca, V; Del Prete, S; Osman, SM; Scozzafava, A; Supuran, CT; Vullo, D2
Barboiu, M; Cristian, A; Nasr, G; Supuran, CT; Vullo, D; Winum, JY1
Capasso, C; Minakuchi, T; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D1
Brożewicz, K; Pogorzelska, A; Supuran, CT; Sławiński, J; Vullo, D; Żołnowska, B1
Brzozowski, Z; Pogorzelska, A; Supuran, CT; Szafrański, K; Sławiński, J; Vullo, D; Żołnowska, B1
AlOthman, Z; Capasso, C; Osman, SM; Prete, SD; Scozzafava, A; Supuran, CT; Vullo, D1
Andrews, KT; Capasso, C; Del Prete, S; Fisher, GM; Poulsen, SA; Supuran, CT; Vullo, D1
Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Scozzafava, A; Supuran, CT; Vullo, D2
Kuuslahti, M; Parkkila, S; Supuran, CT; Syrjänen, L; Tolvanen, M; Vullo, D1
Ceruso, M; Durgun, M; Supuran, CT; Turkmen, H1
Capasso, C; Dedeoglu, N; DeLuca, V; Isik, S; Kockar, F; Supuran, CT; Yildirim, H1
Alothman, Z; Carta, F; Ceruso, M; Monti, SM; Osman, SM; Supuran, CT1
Bhatt, A; Mahon, BP; McKenna, R; Supuran, CT; Vullo, D1
AlOthman, Z; Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Osman, SM; Scozzafava, A; Supuran, CT; Vullo, D1
AlOthman, Z; Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Ferraroni, M; Osman, SM; Supuran, CT; Vullo, D1
Aşık, A; Beldüz, AO; Çanakçı, S; Çolak, DN; Eminoğlu, A; Supuran, CT; Vullo, D1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
AlOthman, Z; Capasso, C; Carginale, V; De Luca, V; Del Prete, S; Osman, SM; Supuran, CT; Vullo, D2
Cadoni, R; Carcelli, M; Dallocchio, R; Dessì, A; Iaccarino, C; Lomelino, C; Mahon, BP; McKenna, R; Pala, N; Rassu, M; Rogolino, D; Sanna, V; Sechi, M; Supuran, CT; Vullo, D1
Gelatt, KN; Gum, G; Gwin, RM; Williams, LW1
Barnikol, WK; Diether, K1
Beall, OV; Lichter, PR; Newman, LP; Wheeler, NC1
Bleckmann, H1
van Rens, JW1
Baer, JE; Beyer, KH1
Biddle, FG1
Barrett, RJ; Gathright, CE; Nolan, JC; Radvany, CH; Sancilio, LF1
Coulson, RA1
Kold, A1
Bagby, GC; Dreis, MW; Fraunfelder, FT; Meyer, SM1
Lotti, VJ; Stone, CA; Torchiana, ML1
Chignell, CF; Starkweather, DK1
Murao, M; Onodera, S1
Breffeilh, LA1
Maren, TH; Sanders, E2
Leeling, JL; Phillips, BM1
Bietti, GB; Pecori-Giraldi, J; Pivetti-Pezzi, P; Virno, M1
Flenley, DC; Iff, HW1
Evans, PJ1
Leonardi, E; Pecori-Giraldi, J; Pivetti-Pezzi, P; Virno, M1
Burberi, P; Piccinelli, D; Silvestrini, B1
Weekers, R1
De Vincentiis, M; Marmo, F1
Kanski, JJ1
Borgmann, AR; Hodges, JW; Leaders, FE; McDonald, TO1
Pirch, JH; Sullivan, LP1
Shoji, Y1
Coulson, RA; Herbert, JD1
Baird, IM; Cowan, RA; Hartnell, GG; Leak, AM; Lowdell, CP1
FORD, RV; MOYER, JH; ROCHELLE, JB1
BEEBE, JL; COULSON, RA; HERNANDEZ, T1
GONZALES-JIMENEZ, E; LEOPOLD, IH1
BALLAN, JV; LEPLEY, FJ; OTTUM, JA; SCHIMEK, RA1
RICHARDSON, W; THOMPSON, WT; WINGO, CF1
HENRY, MM; LEE, PF1
MOSQUERA, JM1
SADOUL, P1
URRETS ZAVALIA, A1
DEGRAEVE, M; POIRE, R; ROYER, P; RUSTIN, C1
LABADIE, P1
LEREBOULLET, J1
BIETTI, G1
FREZZOTTI, R; GENTILI, MC1
DEGRAFF, AC; LYON, AF1
DOYLE, D; HARRIS, EA; SLAWSON, KB1
HOSHIWARA, I1
TOJO, H; TSUJI, M1
HUTCHEON, DE; MEHTA, D; ROMANO, A1
Luntz, MH1
Links, TP; Meola, G; Panzeri, M; Rose, MR; Sansone, V1
Camerino, DC; Lovaglio, S; Mancinelli, E; Mele, A; Meola, G; Rotondo, G; Tricarico, D1
Ammon, DM; Borazjani, RN; Foster, WJ; Garcia, CA; Hacker, MC; Haesslein, A; Kunzler, JF; Mikos, AG; Salamone, JC; Ueda, H1
Gupta, A; Iyadurai, S; LoRusso, S; Roggenbuck, J1

Reviews

5 review(s) available for dichlorphenamide and acetazolamide

ArticleYear
Carbonic anhydrases as targets for medicinal chemistry.
    Bioorganic & medicinal chemistry, 2007, Jul-01, Volume: 15, Issue:13

    Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Isoenzymes; Models, Molecular; Tissue Distribution

2007
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Treatment of chronic cor pulmonale].
    Naika. Internal medicine, 1967, Volume: 19, Issue:6

    Topics: Acetazolamide; Adrenal Cortex Hormones; Bronchodilator Agents; Dichlorphenamide; Humans; Pulmonary Heart Disease; Salicylates; Tromethamine

1967
Treatment for periodic paralysis.
    The Cochrane database of systematic reviews, 2008, Jan-23, Issue:1

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Humans; Hypokalemic Periodic Paralysis; Paralysis, Hyperkalemic Periodic; Pinacidil; Randomized Controlled Trials as Topic

2008
Marked reduction in paralytic attacks in a patient with Andersen-Tawil syndrome switched from acetazolamide to dichlorphenamide.
    Neuromuscular disorders : NMD, 2021, Volume: 31, Issue:7

    Topics: Acetazolamide; Andersen Syndrome; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Female; Humans; Muscle Weakness; Potassium Channels, Inwardly Rectifying; Young Adult

2021

Trials

4 trial(s) available for dichlorphenamide and acetazolamide

ArticleYear
Patient tolerance to carbonic anhydrase inhibitors.
    American journal of ophthalmology, 1978, Volume: 85, Issue:4

    Topics: Acetazolamide; Anorexia; Carbonic Anhydrase Inhibitors; Confusion; Dichlorphenamide; Drug Evaluation; Ethoxzolamide; Fatigue; Glaucoma; Humans; Intraocular Pressure; Methazolamide

1978
[Dichlorphenamide treatment in acute glaucoma (author's transl)].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1976, Nov-18, Volume: 201, Issue:1

    Topics: Acetazolamide; Acid-Base Equilibrium; Acute Disease; Clinical Trials as Topic; Dichlorphenamide; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Potassium; Sodium

1976
The ventilatory response to CO 2 after administration of frusemide in normal man.
    Clinical science, 1972, Volume: 43, Issue:1

    Topics: Acetazolamide; Administration, Oral; Adult; Alkalosis; Arteries; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Chlorides; Chlorothiazide; Dichlorphenamide; Diuretics; Ethacrynic Acid; Female; Furosemide; Humans; Hydrogen-Ion Concentration; Male; Potassium; Respiration; Sodium; Time Factors

1972
GLAUCOMA TREATED WITH DARANIDE A CLINICAL TRIAL.
    The British journal of ophthalmology, 1961, Volume: 45, Issue:2

    Topics: Acetazolamide; Aged; Carbonic Anhydrase Inhibitors; Chronic Disease; Dichlorphenamide; Drug Therapy, Combination; Female; Glaucoma; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Tonometry, Ocular

1961

Other Studies

171 other study(ies) available for dichlorphenamide and acetazolamide

ArticleYear
Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:12

    Topics: Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Glaucoma; Guinea Pigs; Intraocular Pressure; Ocular Hypertension; Rabbits; Skin; Sulfonamides; Thiophenes

1989
Topically active carbonic anhydrase inhibitors. 1. O-acyl derivatives of 6-hydroxybenzothiazole-2-sulfonamide.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:11

    Topics: Animals; Benzothiazoles; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Cornea; Ethoxzolamide; Guinea Pigs; Humans; Intraocular Pressure; Ophthalmic Solutions; Prodrugs; Rabbits; Thiazoles

1989
Carbonic anhydrase inhibitors: perfluoroalkyl/aryl-substituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure-lowering agents with prolonged duration of action.
    Journal of medicinal chemistry, 2000, Nov-16, Volume: 43, Issue:23

    Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cattle; Glaucoma; Humans; Intraocular Pressure; Isoenzymes; Lung; Rabbits; Solubility; Structure-Activity Relationship; Sulfonamides; Tissue Distribution; Uvea

2000
Carbonic anhydrase inhibitors: water-soluble 4-sulfamoylphenylthioureas as topical intraocular pressure-lowering agents with long-lasting effects.
    Journal of medicinal chemistry, 2000, Dec-14, Volume: 43, Issue:25

    Topics: Animals; Carbonic Anhydrase Inhibitors; Cornea; Eye; Glaucoma; Hydrogen-Ion Concentration; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Solubility; Structure-Activity Relationship; Sulfonamides; Thiourea; Tissue Distribution; Water

2000
Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.
    Journal of medicinal chemistry, 2002, Mar-28, Volume: 45, Issue:7

    Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chelating Agents; Chloroform; Chromatography, High Pressure Liquid; Cornea; DNA, Complementary; Edetic Acid; Enzyme Inhibitors; Escherichia coli; Glaucoma; Humans; Hydrogen-Ion Concentration; Imino Acids; Kinetics; Male; Models, Chemical; Nitrilotriacetic Acid; Pentetic Acid; Pressure; Rabbits; Sulfonamides; Temperature; Time Factors; Ultraviolet Rays; Water

2002
Carbonic anhydrase inhibitors. Preparation of potent sulfonamides inhibitors incorporating bile acid tails.
    Bioorganic & medicinal chemistry letters, 2002, Jun-17, Volume: 12, Issue:12

    Topics: Bile Acids and Salts; Carbonic Anhydrase Inhibitors; Sulfonamides

2002
Successful virtual screening for novel inhibitors of human carbonic anhydrase: strategy and experimental confirmation.
    Journal of medicinal chemistry, 2002, Aug-15, Volume: 45, Issue:17

    Topics: Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Databases, Factual; Humans; Isoenzymes; Ligands; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship

2002
Carbonic anhydrase inhibitors: inhibition of cytosolic isozymes I and II with sulfamide derivatives.
    Bioorganic & medicinal chemistry letters, 2003, Mar-10, Volume: 13, Issue:5

    Topics: Amines; Binding Sites; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Cytosol; Humans; Models, Molecular; Structure-Activity Relationship; Sulfonamides

2003
Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV.
    Bioorganic & medicinal chemistry letters, 2003, Mar-10, Volume: 13, Issue:5

    Topics: Animals; Binding Sites; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Cattle; Crystallography, X-Ray; Fructose; Humans; Hydrogen Bonding; Models, Molecular; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids; Topiramate; Zinc

2003
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.
    Bioorganic & medicinal chemistry letters, 2003, Mar-24, Volume: 13, Issue:6

    Topics: Animals; Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cattle; Heterocyclic Compounds; Humans; Hydrocarbons, Aromatic; Isoenzymes; Kinetics; Neoplasm Proteins; Neoplasms; Structure-Activity Relationship; Sulfonamides

2003
Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives.
    Journal of medicinal chemistry, 2003, May-22, Volume: 46, Issue:11

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Benzene Derivatives; Bromine; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase IV; Carbonic Anhydrase IX; Carbonic Anhydrases; Chlorine; Enzyme Inhibitors; Humans; Iodine; Neoplasm Proteins; Structure-Activity Relationship; Sulfanilamides; Sulfonamides

2003
Carbonic anhydrase inhibitors: N-(p-sulfamoylphenyl)-alpha-D-glycopyranosylamines as topically acting antiglaucoma agents in hypertensive rabbits.
    Bioorganic & medicinal chemistry letters, 2004, Jan-05, Volume: 14, Issue:1

    Topics: Administration, Topical; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Hypertension; Intraocular Pressure; Male; Monosaccharides; Rabbits; Sulfanilamides

2004
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride.
    Bioorganic & medicinal chemistry letters, 2004, Jan-19, Volume: 14, Issue:2

    Topics: Antipsychotic Agents; Binding Sites; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Humans; Isoenzymes; Sulpiride

2004
Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.
    Journal of medicinal chemistry, 2004, Jan-29, Volume: 47, Issue:3

    Topics: Animals; Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Celecoxib; Crystallography, X-Ray; Cyclooxygenase 2; Intraocular Pressure; Isoenzymes; Isoxazoles; Kinetics; Lactones; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rabbits; Structure-Activity Relationship; Sulfonamides; Sulfones

2004
Carbonic anhydrase inhibitors. Inhibition of mitochondrial isozyme V with aromatic and heterocyclic sulfonamides.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Animals; Benzene Derivatives; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase V; Coumarins; Mice; Mitochondria; Structure-Activity Relationship; Sulfonamides; Thiadiazoles

2004
Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX.
    Bioorganic & medicinal chemistry letters, 2004, Feb-23, Volume: 14, Issue:4

    Topics: Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Humans; Isoenzymes; Molecular Structure; Neoplasm Proteins; Sulfonamides

2004
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered.
    Bioorganic & medicinal chemistry letters, 2004, May-03, Volume: 14, Issue:9

    Topics: Carbonic Anhydrase Inhibitors; Fluorine; Isoenzymes; Sulfonamides

2004
Carbonic anhydrase inhibitors. Design of selective, membrane-impermeant inhibitors targeting the human tumor-associated isozyme IX.
    Journal of medicinal chemistry, 2004, Apr-22, Volume: 47, Issue:9

    Topics: Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Erythrocyte Membrane; Humans; In Vitro Techniques; Isoenzymes; Permeability; Pyridinium Compounds; Structure-Activity Relationship; Sulfonamides

2004
Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity.
    Journal of medicinal chemistry, 2004, May-20, Volume: 47, Issue:11

    Topics: Administration, Topical; Animals; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Fluorine; Glaucoma; Heterocyclic Compounds; Intraocular Pressure; Rabbits; Structure-Activity Relationship; Sulfonamides

2004
Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides.
    Bioorganic & medicinal chemistry letters, 2004, Jun-21, Volume: 14, Issue:12

    Topics: Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Isoenzymes; Quantitative Structure-Activity Relationship; Sulfonamides

2004
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.
    Bioorganic & medicinal chemistry letters, 2004, Jul-16, Volume: 14, Issue:14

    Topics: Amino Acid Sequence; Animals; Carbonic Anhydrase Inhibitors; Cytosol; Drug Design; Humans; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Molecular Sequence Data; Neoplasms; Rats; Structure-Activity Relationship; Sulfonamides

2004
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties.
    Bioorganic & medicinal chemistry letters, 2004, Nov-01, Volume: 14, Issue:21

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cytosol; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Sulfonamides; Triazines

2004
Carbonic anhydrase inhibitors: the first on-resin screening of a 4-sulfamoylphenylthiourea library.
    Journal of medicinal chemistry, 2004, Oct-07, Volume: 47, Issue:21

    Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Combinatorial Chemistry Techniques; Databases, Factual; Humans; Structure-Activity Relationship; Sulfonamides; Thiourea

2004
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.
    Bioorganic & medicinal chemistry letters, 2004, Dec-06, Volume: 14, Issue:23

    Topics: Benzolamide; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cytosol; Humans; Neoplasms; Nerve Tissue Proteins; Sulfonamides

2004
Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.
    Bioorganic & medicinal chemistry letters, 2004, Dec-20, Volume: 14, Issue:24

    Topics: Archaea; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Isoenzymes; Molecular Structure; Structure-Activity Relationship; Sulfonamides

2004
Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.
    Bioorganic & medicinal chemistry letters, 2005, Jan-17, Volume: 15, Issue:2

    Topics: Acetazolamide; Amines; Biomarkers, Tumor; Carbonic Anhydrase Inhibitors; Catalysis; Cytosol; Heterocyclic Compounds; Humans; Isoenzymes; Morpholines; Piperazine; Piperazines; Piperidines; Structure-Activity Relationship; Sulfanilamide; Sulfanilamides

2005
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with bis-sulfamates.
    Bioorganic & medicinal chemistry letters, 2005, Feb-01, Volume: 15, Issue:3

    Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cytosol; Humans; Isoenzymes; Neoplasm Proteins; Structure-Activity Relationship; Sulfonic Acids

2005
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?
    Bioorganic & medicinal chemistry letters, 2005, Feb-15, Volume: 15, Issue:4

    Topics: Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Drug Design; Glaucoma; Humans; Isoenzymes; Structure-Activity Relationship; Sulfonamides

2005
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.
    Bioorganic & medicinal chemistry letters, 2005, Feb-15, Volume: 15, Issue:4

    Topics: Anticonvulsants; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Heterocyclic Compounds; Humans; Hydrocarbons, Aromatic; Isoenzymes; Protein Subunits; Structure-Activity Relationship; Sulfonamides

2005
Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides.
    Bioorganic & medicinal chemistry letters, 2005, Feb-15, Volume: 15, Issue:4

    Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IV; Cattle; Dose-Response Relationship, Drug; Humans; Isoenzymes; Kinetics; Membrane Proteins; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids

2005
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/membrane-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating hydrazino moieties.
    Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Membrane; Cytosol; Hydrazines; Isocyanates; Isoenzymes; Structure-Activity Relationship; Sulfonamides

2005
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.
    Bioorganic & medicinal chemistry letters, 2005, May-02, Volume: 15, Issue:9

    Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Catalytic Domain; Cytosol; Humans; Kinetics; Neoplasms; Structure-Activity Relationship; Sulfonamides; Urea

2005
Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.
    Bioorganic & medicinal chemistry letters, 2005, Jun-15, Volume: 15, Issue:12

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Membrane; Cytosol; Humans; Isoenzymes; Molecular Structure; Structure-Activity Relationship; Sulfonamides; Triazines

2005
Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes.
    Bioorganic & medicinal chemistry letters, 2005, Jun-15, Volume: 15, Issue:12

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Membrane; Chromones; Cytosol; Humans; Isoenzymes; Molecular Structure; Nerve Tissue Proteins; Schiff Bases; Structure-Activity Relationship; Sulfonamides; Zinc Compounds

2005
Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.
    Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15

    Topics: Animals; Antigens, Neoplasm; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Catalytic Domain; Cell Hypoxia; Cell Line; Cell Membrane Permeability; Dogs; Erythrocyte Membrane; Extracellular Fluid; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Isoenzymes; Mutation; Sequence Deletion; Sulfonamides

2005
Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.
    Bioorganic & medicinal chemistry letters, 2005, Sep-01, Volume: 15, Issue:17

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Fructose; Humans; Kinetics; Membrane Proteins; Protein Binding; Structure-Activity Relationship; Sulfonamides; Topiramate

2005
Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma.
    Bioorganic & medicinal chemistry letters, 2005, Sep-01, Volume: 15, Issue:17

    Topics: Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Disease Models, Animal; Drug Design; Glaucoma; Intraocular Pressure; Rabbits; Structure-Activity Relationship; Sulfonamides

2005
Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides.
    Bioorganic & medicinal chemistry letters, 2005, Nov-01, Volume: 15, Issue:21

    Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cytosol; Humans; Neoplasm Proteins; Structure-Activity Relationship

2005
Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib.
    Bioorganic & medicinal chemistry letters, 2006, Jan-15, Volume: 16, Issue:2

    Topics: Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Celecoxib; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Humans; Isoenzymes; Isoxazoles; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrazoles; Structure-Activity Relationship; Sulfonamides; Topoisomerase II Inhibitors

2006
Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors.
    Journal of medicinal chemistry, 2005, Dec-01, Volume: 48, Issue:24

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase V; Catalysis; Cloning, Molecular; Humans; Isoenzymes; Kinetics; Mitochondria; Molecular Sequence Data; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids

2005
Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.
    Bioorganic & medicinal chemistry letters, 2006, Apr-15, Volume: 16, Issue:8

    Topics: Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Structure-Activity Relationship; Sulfonamides

2006
Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.
    Journal of medicinal chemistry, 2006, Mar-23, Volume: 49, Issue:6

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; DNA, Bacterial; Gastric Mucosa; Gastritis; Helicobacter pylori; Humans; Molecular Sequence Data; Polymorphism, Genetic; Stomach Neoplasms; Stomach Ulcer; Sulfonamides; Sulfonic Acids

2006
Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors.
    Bioorganic & medicinal chemistry letters, 2006, Sep-15, Volume: 16, Issue:18

    Topics: Carbonic Anhydrase Inhibitors; Cell Hypoxia; Cell Membrane; Cytosol; Humans; Isoenzymes; Molecular Structure; Neoplasms; Sulfonamides; Water

2006
Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX.
    Journal of medicinal chemistry, 2006, Sep-07, Volume: 49, Issue:18

    Topics: Antigens, Neoplasm; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Crystallography, X-Ray; Disulfides; Enzyme Activation; Humans; Hydrogen Bonding; Hypoxia; Isoenzymes; Models, Molecular; Molecular Structure; Neoplasms; Prodrugs; Protein Binding; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfonamides

2006
A novel class of carbonic anhydrase inhibitors: glycoconjugate benzene sulfonamides prepared by "click-tailing".
    Journal of medicinal chemistry, 2006, Nov-02, Volume: 49, Issue:22

    Topics: Benzene Derivatives; Carbohydrate Sequence; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Glycosylation; Indicators and Reagents; Isoenzymes; Molecular Sequence Data; Sulfonamides

2006
Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue.
    Journal of medicinal chemistry, 2006, Nov-30, Volume: 49, Issue:24

    Topics: Alanine; Anticonvulsants; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Drug Design; Fructose; Hydrogen Bonding; Isoenzymes; Models, Molecular; Molecular Structure; Protein Binding; Structure-Activity Relationship; Sulfonamides; Topiramate

2006
Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides.
    Bioorganic & medicinal chemistry letters, 2007, Feb-15, Volume: 17, Issue:4

    Topics: Carbonic Anhydrase Inhibitors; Cyclization; Glycoconjugates; Humans; Isoenzymes; Membranes; Phenolsulfonphthalein; Recombinant Proteins; Sulfonamides

2007
Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.
    Journal of medicinal chemistry, 2007, Jan-25, Volume: 50, Issue:2

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalysis; Cloning, Molecular; DNA; Humans; Isoenzymes; Molecular Sequence Data; Protein Subunits; Sequence Homology, Amino Acid; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids

2007
Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated isoforms I, II, and IX with iminodiacetic carboxylates/hydroxamates also incorporating benzenesulfonamide moieties.
    Bioorganic & medicinal chemistry letters, 2007, Mar-15, Volume: 17, Issue:6

    Topics: Carbonic Anhydrase Inhibitors; Cell Membrane; Cytosol; Humans; Hydroxamic Acids; Indicators and Reagents; Isoenzymes; Neoplasms; Structure-Activity Relationship; Sulfonamides

2007
Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates.
    Bioorganic & medicinal chemistry, 2007, Mar-15, Volume: 15, Issue:6

    Topics: Animals; Carbonic Anhydrase I; Carbonic Anhydrase II; Cytosol; Enzyme Inhibitors; Humans; Hydroxamic Acids; Isoenzymes; Matrix Metalloproteinase Inhibitors; Mice; Molecular Structure; Multiple Myeloma; Structure-Activity Relationship; Sulfonic Acids; Tumor Cells, Cultured

2007
Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides.
    Journal of medicinal chemistry, 2007, Apr-05, Volume: 50, Issue:7

    Topics: Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase III; Carbonic Anhydrase Inhibitors; Galactosides; Glycosides; Isoenzymes; Structure-Activity Relationship; Sulfonamides; Triazoles

2007
Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors.
    Bioorganic & medicinal chemistry letters, 2007, Jul-01, Volume: 17, Issue:13

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chemistry, Pharmaceutical; Cloning, Molecular; Drug Design; Enzyme Inhibitors; Helicobacter pylori; Humans; Molecular Sequence Data; Recombinant Proteins; Sequence Homology, Amino Acid; Stomach Neoplasms; Stomach Ulcer; Sulfonamides

2007
Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studies.
    Bioorganic & medicinal chemistry letters, 2007, Aug-01, Volume: 17, Issue:15

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Crystallography, X-Ray; Hydrogen Bonding; Isoenzymes; Models, Molecular; Sulfonamides

2007
Carbonic anhydrase inhibitors: Selective inhibition of the extracellular, tumor-associated isoforms IX and XII over isozymes I and II with glycosyl-thioureido-sulfonamides.
    Bioorganic & medicinal chemistry letters, 2007, Sep-15, Volume: 17, Issue:18

    Topics: Carbonic Anhydrase Inhibitors; Isoenzymes; Sulfonamides

2007
Inhibition of carbonic anhydrase isozymes I, II and IX with benzenesulfonamides containing an organometallic moiety.
    Bioorganic & medicinal chemistry letters, 2007, Sep-15, Volume: 17, Issue:18

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Isoenzymes; Magnetic Resonance Spectroscopy; Organometallic Compounds; Substrate Specificity; Sulfonamides

2007
Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.
    Bioorganic & medicinal chemistry, 2007, Dec-01, Volume: 15, Issue:23

    Topics: Amino Acid Sequence; Carbonic Anhydrase III; Carbonic Anhydrase Inhibitors; Cloning, Molecular; Cytosol; Enzyme Activation; Humans; Isoenzymes; Kinetics; Molecular Sequence Data; Recombinant Proteins; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids

2007
Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.
    Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7

    Topics: Benzenesulfonamides; Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cytosol; Humans; Hydrocarbons, Chlorinated; Isoenzymes; Methylation; Models, Molecular; Molecular Sequence Data; Molecular Structure; Neoplasms; Protein Folding; Sequence Alignment; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfonamides

2008
Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Antigens, Neoplasm; Benzene Derivatives; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Glycosides; Humans; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Triazoles

2008
Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors.
    Bioorganic & medicinal chemistry letters, 2008, Apr-15, Volume: 18, Issue:8

    Topics: Animals; Binding Sites; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Catalysis; Crystallography, X-Ray; Ethoxzolamide; Glutamine; Humans; Isoenzymes; Mice; Models, Molecular; Molecular Structure; Protein Binding; Threonine

2008
Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct.
    Bioorganic & medicinal chemistry letters, 2008, Apr-15, Volume: 18, Issue:8

    Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Computer Simulation; Crystallography, X-Ray; Humans; Indapamide; Isoenzymes; Mice; Models, Molecular; Molecular Structure

2008
Carbonic anhydrase inhibitors: bioreductive nitro-containing sulfonamides with selectivity for targeting the tumor associated isoforms IX and XII.
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Amino Acid Sequence; Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Conserved Sequence; Crystallography, X-Ray; Humans; Isoenzymes; Models, Molecular; Molecular Sequence Data; Neoplasms; Nitro Compounds; Structure-Activity Relationship; Sulfonamides

2008
Carbonic anhydrase inhibitors: design of spin-labeled sulfonamides incorporating TEMPO moieties as probes for cytosolic or transmembrane isozymes.
    Bioorganic & medicinal chemistry letters, 2008, Jun-15, Volume: 18, Issue:12

    Topics: Antigens, Neoplasm; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Membrane; Cyclic N-Oxides; Cytosol; Drug Design; Drug Evaluation, Preclinical; Free Radicals; Humans; Isoenzymes; Molecular Structure; Recombinant Proteins; Spin Labels; Stereoisomerism; Structure-Activity Relationship; Sulfonamides

2008
Carbonic anhydrase inhibitors. Biphenylsulfonamides with inhibitory action towards the transmembrane, tumor-associated isozymes IX possess cytotoxic activity against human colon, lung and breast cancer cell lines.
    Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; HCT116 Cells; Humans; Isoenzymes; Lung Neoplasms; Sulfonamides

2009
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates.
    Bioorganic & medicinal chemistry, 2009, Feb-01, Volume: 17, Issue:3

    Topics: Amino Acid Sequence; Antifungal Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Kinetics; Molecular Sequence Data; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sulfonamides; Sulfonic Acids

2009
Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV.
    Journal of medicinal chemistry, 2009, Feb-12, Volume: 52, Issue:3

    Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Isoenzymes; Kidney; Mice; Protein Processing, Post-Translational

2009
A QSAR study on relationship between structure of sulfonamides and their carbonic anhydrase inhibitory activity using the eigenvalue (EVA) method.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:9

    Topics: Artificial Intelligence; Carbonic Anhydrase II; Computer Simulation; Isoenzymes; Models, Chemical; Quantitative Structure-Activity Relationship; Sulfonamides

2009
Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate.
    Journal of medicinal chemistry, 2009, Apr-23, Volume: 52, Issue:8

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalysis; Cloning, Molecular; Drug Resistance, Multiple, Bacterial; Humans; Molecular Sequence Data; Mycobacterium tuberculosis; Recombinant Proteins; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids

2009
Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis.
    Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9

    Topics: Amino Acid Sequence; Biocatalysis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis; Sulfonamides; Sulfonic Acids

2009
Carbonic anhydrase inhibitors. Inhibition of the fungal beta-carbonic anhydrases from Candida albicans and Cryptococcus neoformans with boronic acids.
    Bioorganic & medicinal chemistry letters, 2009, May-15, Volume: 19, Issue:10

    Topics: Boronic Acids; Candida albicans; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cryptococcus neoformans; Humans; Structure-Activity Relationship

2009
Carbonic anhydrase inhibitors. Synthesis of 2,4,6-trimethylpyridinium derivatives of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides acting as potent inhibitors of the tumor-associated isoform IX and XII.
    Bioorganic & medicinal chemistry letters, 2009, Jun-01, Volume: 19, Issue:11

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Humans; Pyridinium Compounds; Sulfonamides

2009
Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides.
    Bioorganic & medicinal chemistry, 2009, Jul-01, Volume: 17, Issue:13

    Topics: Amino Acid Sequence; Antifungal Agents; Bacterial Proteins; Candida albicans; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cryptococcus neoformans; Helicobacter pylori; Humans; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Sequence Alignment; Structure-Activity Relationship; Sulfonamides

2009
Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides.
    Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14

    Topics: Amino Acid Sequence; Animals; Anthozoa; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Molecular Sequence Data; Molecular Structure; Recombinant Proteins; Sequence Alignment; Sulfonamides

2009
Carbonic anhydrase inhibitors: inhibition of cytosolic carbonic anhydrase isozymes II and VII with simple aromatic sulfonamides and some azo dyes.
    Chemical biology & drug design, 2009, Volume: 74, Issue:2

    Topics: Azo Compounds; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Coloring Agents; Humans; Sulfanilamide; Sulfanilamides

2009
Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c.
    Bioorganic & medicinal chemistry letters, 2009, Dec-01, Volume: 19, Issue:23

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalytic Domain; Drug Design; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship

2009
Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis.
    Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brucella suis; Brucellosis; Carbonic Anhydrases; Cloning, Molecular; DNA, Bacterial; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Polymerase Chain Reaction; Sequence Alignment; Sequence Analysis, DNA; Structure-Activity Relationship; Sulfonamides

2010
Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cytosol; Humans; Isoenzymes; Sulfonamides

2010
Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:9

    Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Membrane; Cytosol; Humans; Isoenzymes; Neoplasms; Stereoisomerism; Substrate Specificity; Sulfonamides

2010
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.
    Journal of medicinal chemistry, 2010, Aug-12, Volume: 53, Issue:15

    Topics: Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Humans; Isoenzymes; Models, Molecular; Polyamines; Spermine; Structure-Activity Relationship; Water; Zinc

2010
Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.
    Bioorganic & medicinal chemistry letters, 2011, Jan-15, Volume: 21, Issue:2

    Topics: Animals; Anions; Anthozoa; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Structure-Activity Relationship; Sulfonamides

2011
A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth.
    Bioorganic & medicinal chemistry, 2011, Feb-01, Volume: 19, Issue:3

    Topics: Anti-Bacterial Agents; Brucella suis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Drug Design; Drug Discovery; Inhibitory Concentration 50; Kinetics; Sulfonamides; Sulfonic Acids

2011
(R)-/(S)-10-camphorsulfonyl-substituted aromatic/heterocyclic sulfonamides selectively inhibit mitochondrial over cytosolic carbonic anhydrases.
    Bioorganic & medicinal chemistry letters, 2011, Mar-01, Volume: 21, Issue:5

    Topics: Animals; Camphor; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cytosol; Enzyme Assays; Heterocyclic Compounds; Humans; Mitochondria; Molecular Structure; Stereoisomerism; Sulfonamides

2011
Purification and inhibition studies with anions and sulfonamides of an α-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii.
    Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6

    Topics: Animals; Anions; Antarctic Regions; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Protein Isoforms; Seals, Earless; Sulfonamides

2011
Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII.
    Bioorganic & medicinal chemistry letters, 2011, May-15, Volume: 21, Issue:10

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Boron Compounds; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Enzyme Activation; Humans; Molecular Structure; Neoplasm Proteins; Oxazolidinones; Protein Isoforms; Structure-Activity Relationship; Sulfonamides

2011
Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.
    Bioorganic & medicinal chemistry, 2011, May-15, Volume: 19, Issue:10

    Topics: Antifungal Agents; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Cytosol; Fungi; Humans; Isoenzymes; Models, Molecular; Structure-Activity Relationship; Sulfonamides; Triazines

2011
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action.
    Bioorganic & medicinal chemistry letters, 2011, Jun-01, Volume: 21, Issue:11

    Topics: Animals; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Disease Models, Animal; Glaucoma; Humans; Models, Molecular; Molecular Structure; Nitric Oxide; Ocular Hypertension; Protein Isoforms; Rabbits; Sulfonamides; Thiophenes

2011
Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms.
    Bioorganic & medicinal chemistry, 2011, Jun-15, Volume: 19, Issue:12

    Topics: Acetamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalytic Domain; Crystallography, X-Ray; Cytosol; Enzyme Activation; Humans; Isoenzymes; Models, Molecular; Molecular Structure; Protein Binding; Structure-Activity Relationship; Sulfonamides

2011
Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates.
    Bioorganic & medicinal chemistry, 2011, Aug-15, Volume: 19, Issue:16

    Topics: Anti-Bacterial Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Salmonella Infections; Salmonella typhimurium; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids

2011
Carbonic anhydrase inhibitors. Synthesis, molecular structures, and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with novel 3-pyridinesulfonamide derivatives.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Carbonic Anhydrase Inhibitors; Cytosol; Humans; Isoenzymes; Magnetic Resonance Spectroscopy; Models, Molecular; Sulfonamides

2011
Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.
    Bioorganic & medicinal chemistry letters, 2011, Oct-01, Volume: 21, Issue:19

    Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cytosol; Drug Screening Assays, Antitumor; Humans; Isoenzymes; Molecular Targeted Therapy; Neoplasms; Stereoisomerism; Structure-Activity Relationship; Sulfonamides

2011
Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.
    Bioorganic & medicinal chemistry, 2012, Feb-15, Volume: 20, Issue:4

    Topics: Amino Acid Sequence; Animals; Carbonic Anhydrases; Cloning, Molecular; Fossils; Humans; Molecular Sequence Data; Porifera; Protein Binding; Sequence Alignment; Sulfonamides; Sulfonic Acids

2012
Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target.
    Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7

    Topics: Amino Acid Sequence; Animals; Antifungal Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Dermatomycoses; Fungal Proteins; Humans; Isoenzymes; Malassezia; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Recombinant Fusion Proteins; Scalp Dermatoses; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids

2012
Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups.
    Journal of medicinal chemistry, 2012, Aug-09, Volume: 55, Issue:15

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Crystallography, X-Ray; Enzyme Assays; Humans; Isoenzymes; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Sulfonamides

2012
The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides.
    Bioorganic & medicinal chemistry, 2013, Mar-15, Volume: 21, Issue:6

    Topics: Amino Acid Sequence; Bacteria; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Protein Binding; Recombinant Proteins; Sequence Alignment; Sulfonamides

2013
Carbonic anhydrase inhibitors. Regioselective synthesis of novel series 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.
    European journal of medicinal chemistry, 2012, Volume: 56

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Isoenzymes; Molecular Structure; Pyridines; Stereoisomerism; Structure-Activity Relationship; Sulfonamides

2012
DNA cloning, characterization, and inhibition studies of an α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.
    Journal of medicinal chemistry, 2012, Dec-13, Volume: 55, Issue:23

    Topics: Amino Acid Sequence; Biocatalysis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; DNA; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Vibrio cholerae

2012
Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease.
    Journal of medicinal chemistry, 2013, Feb-28, Volume: 56, Issue:4

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chagas Disease; Cloning, Molecular; Humans; Molecular Sequence Data; Phylogeny; Protozoan Proteins; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfonamides; Thiadiazoles; Trypanocidal Agents; Trypanosoma cruzi

2013
Carbonic anhydrase inhibitors: inhibition of the β-class enzyme from the pathogenic yeast Candida glabrata with sulfonamides, sulfamates and sulfamides.
    Bioorganic & medicinal chemistry letters, 2013, May-01, Volume: 23, Issue:9

    Topics: Acetazolamide; Amino Acid Sequence; Antifungal Agents; Candida glabrata; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Protein Binding; Sequence Alignment; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids

2013
Cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Leishmania donovani chagasi, the protozoan parasite responsible for leishmaniasis.
    Journal of medicinal chemistry, 2013, Sep-26, Volume: 56, Issue:18

    Topics: Amino Acid Sequence; Antiprotozoal Agents; Biocatalysis; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Leishmania infantum; Leishmaniasis; Molecular Sequence Data

2013
Structure-based screening for the discovery of new carbonic anhydrase VII inhibitors.
    European journal of medicinal chemistry, 2014, Volume: 71

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Drug Design; Humans; Molecular Docking Simulation; Structure-Activity Relationship

2014
Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associat
    European journal of medicinal chemistry, 2014, Volume: 71

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Line, Tumor; Cytosol; Guanidines; Humans; Isoenzymes; Models, Molecular; Neoplasms; Structure-Activity Relationship

2014
Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii.
    Bioorganic & medicinal chemistry letters, 2014, Jan-01, Volume: 24, Issue:1

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Diatoms; Dose-Response Relationship, Drug; Molecular Structure; Structure-Activity Relationship; Sulfonamides

2014
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis.
    Bioorganic & medicinal chemistry letters, 2014, Jan-01, Volume: 24, Issue:1

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Porphyromonas gingivalis; Structure-Activity Relationship; Sulfonamides

2014
Carbonic anhydrase inhibitors. Inhibition of human cytosolic isoforms I and II with (reduced) Schiff's bases incorporating sulfonamide, carboxylate and carboxymethyl moieties.
    Bioorganic & medicinal chemistry, 2014, May-15, Volume: 22, Issue:10

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Carboxylic Acids; Dose-Response Relationship, Drug; Humans; Isoenzymes; Molecular Structure; Schiff Bases; Structure-Activity Relationship; Sulfonamides

2014
Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila.
    Bioorganic & medicinal chemistry, 2014, Jun-01, Volume: 22, Issue:11

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Legionella pneumophila; Molecular Sequence Data; Molecular Structure; Sequence Alignment; Structure-Activity Relationship; Sulfonamides

2014
Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Membrane; Dose-Response Relationship, Drug; Humans; Isoenzymes; Molecular Structure; Neoplasms; Structure-Activity Relationship; Sulfonamides

2014
Synthesis of a new series of N⁴-substituted 4-(2-aminoethyl)benzenesulfonamides and their inhibitory effect on human carbonic anhydrase cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII.
    European journal of medicinal chemistry, 2014, Sep-12, Volume: 84

    Topics: Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Isoenzymes; Molecular Structure; Structure-Activity Relationship; Sulfonamides

2014
Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the β-class (PgiCAb) versus the γ-class (PgiCA) enzymes.
    Bioorganic & medicinal chemistry, 2014, Sep-01, Volume: 22, Issue:17

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Sequence Data; Molecular Structure; Phylogeny; Porphyromonas gingivalis; Structure-Activity Relationship; Sulfonamides

2014
Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum.
    Bioorganic & medicinal chemistry, 2015, Feb-01, Volume: 23, Issue:3

    Topics: Antimalarials; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Plasmodium falciparum; Structure-Activity Relationship; Sulfonamides

2015
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune.
    Bioorganic & medicinal chemistry, 2015, Apr-15, Volume: 23, Issue:8

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Molecular Sequence Data; Nostoc commune; Sequence Alignment; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiazines; Thiophenes

2015
The β-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides.
    Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10

    Topics: Amino Acid Sequence; Animals; Anopheles; Baculoviridae; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Gene Expression; High-Throughput Screening Assays; Insect Proteins; Insecticides; Kinetics; Molecular Sequence Data; Phylogeny; Protons; Recombinant Proteins; Sequence Alignment; Sf9 Cells; Spodoptera; Sulfanilamides

2015
Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII.
    Bioorganic & medicinal chemistry letters, 2015, Jun-01, Volume: 25, Issue:11

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Imines; Isoenzymes; Molecular Structure; Sulfonamides

2015
Sulfonamide inhibition study of the β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans.
    Bioorganic & medicinal chemistry letters, 2015, Jun-01, Volume: 25, Issue:11

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Molecular Structure; Phylogeny; Streptococcus mutans; Sulfonamides

2015
Inhibition studies of bacterial, fungal and protozoan β-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties.
    Bioorganic & medicinal chemistry, 2015, Aug-01, Volume: 23, Issue:15

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antiprotozoal Agents; Bacterial Proteins; Brucella suis; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cryptococcus neoformans; Drug Evaluation, Preclinical; Fungal Proteins; Humans; Leishmania infantum; Protozoan Proteins; Schiff Bases; Sulfanilamide; Sulfanilamides

2015
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.
    Bioorganic & medicinal chemistry letters, 2015, Sep-01, Volume: 25, Issue:17

    Topics: Acclimatization; Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cold Temperature; Humans; Molecular Sequence Data; Phylogeny; Pseudoalteromonas; Sequence Alignment; Sulfonamides

2015
Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA.
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: Anti-Bacterial Agents; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Gammaproteobacteria; Molecular Docking Simulation; Sulfonamides

2016
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea.
    Bioorganic & medicinal chemistry letters, 2016, Feb-15, Volume: 26, Issue:4

    Topics: Alteromonadaceae; Anti-Bacterial Agents; Bacterial Proteins; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Kinetics; Phylogeny; Protein Binding; Sulfanilamide; Sulfanilamides

2016
Sulfonamide inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.
    Bioorganic & medicinal chemistry, 2016, Mar-01, Volume: 24, Issue:5

    Topics: Amino Acid Sequence; Base Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cholera; Crystallography, X-Ray; Humans; Models, Molecular; Molecular Sequence Data; Sulfonamides; Vibrio cholerae

2016
Sulfonamide inhibition studies of the β-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13.
    Bioorganic & medicinal chemistry letters, 2016, Apr-01, Volume: 26, Issue:7

    Topics: Acetazolamide; Benzenesulfonamides; Carbonic Anhydrase I; Carbonic Anhydrase Inhibitors; Enterobacter; Enterobacteriaceae Infections; Humans; Methazolamide; Structure-Activity Relationship; Sulfonamides

2016
Comparison of the sulfonamide inhibition profiles of the α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae.
    Bioorganic & medicinal chemistry letters, 2016, Apr-15, Volume: 26, Issue:8

    Topics: Amino Acid Sequence; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship; Sulfonamides; Vibrio cholerae

2016
Cloning, expression, purification and sulfonamide inhibition profile of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum.
    Bioorganic & medicinal chemistry letters, 2016, 09-01, Volume: 26, Issue:17

    Topics: Amino Acid Sequence; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cloning, Molecular; Humans; Kinetics; Molecular Sequence Data; Plasmodium falciparum; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Structure-Activity Relationship; Sulfonamides

2016
Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors.
    ACS medicinal chemistry letters, 2017, Sep-14, Volume: 8, Issue:9

    Topics:

2017
Ocular hypotensive effects of carbonic anhydrase inhibitors in normotensive and glaucomatous Beagles.
    American journal of veterinary research, 1979, Volume: 40, Issue:3

    Topics: Acetazolamide; Administration, Oral; Animals; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Dog Diseases; Dogs; Ethoxzolamide; Glaucoma; Intraocular Pressure; Methazolamide; Time Factors

1979
[The broncholytic effect of carboanhydrase inhibitors in subjects with healthy lungs (author's transl)].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:10

    Topics: Acetazolamide; Adult; Bronchi; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Humans; Lung Volume Measurements; Male; Methazolamide; Time Factors

1979
[Glaucoma simplex in general practice (a cause for blindness which usually can be prevented)].
    Nederlands tijdschrift voor geneeskunde, 1977, Mar-26, Volume: 121, Issue:13

    Topics: Acetazolamide; Blindness; Dichlorphenamide; Glaucoma; Humans; Tonometry, Ocular

1977
The site and mode of action of some sulfonamide-derived diuretics.
    The Medical clinics of North America, 1975, Volume: 59, Issue:3

    Topics: Acetazolamide; Aminohippuric Acids; Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Chlorides; Chlorothiazide; Chlorthalidone; Cyclopenthiazide; Depression, Chemical; Dichlorphenamide; Diffusion; Diuretics; Hydrochlorothiazide; Kidney Cortex; Kidney Medulla; Natriuresis; Probenecid; Rabbits; Sodium; Trichlormethiazide

1975
Teratogenesis of acetazolamide in the CBA/J and SWV strains of mice. I. Teratology.
    Teratology, 1975, Volume: 11, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Dichlorphenamide; Dose-Response Relationship, Drug; Female; Hybridization, Genetic; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Pregnancy; Time Factors; Toes

1975
Carbonic anhydrase inhibitors are antiarthritic in the rat.
    Pharmacological research, 1991, Volume: 24, Issue:4

    Topics: Acetazolamide; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carbonic Anhydrase Inhibitors; Carrageenan; Dichlorphenamide; Edema; Ethoxzolamide; Female; Indomethacin; Methazolamide; Rats

1991
Delayed protein digestion in the alligator following carbonic anhydrase inhibition.
    Comparative biochemistry and physiology. A, Comparative physiology, 1985, Volume: 82, Issue:1

    Topics: Acetazolamide; Alligators and Crocodiles; Animals; Bicarbonates; Cattle; Chlorides; Dichlorphenamide; Dietary Proteins; Digestion; Fasting; Gastric Acidity Determination; Intestinal Mucosa; Kinetics; Meat; Reptiles

1985
[Treatment of familial hypokalemic paralysis with carbon dioxide anhydrase inhibitors].
    Ugeskrift for laeger, 1986, Jul-07, Volume: 148, Issue:28

    Topics: Acetazolamide; Adult; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Humans; Hypokalemia; Male; Middle Aged; Paralyses, Familial Periodic

1986
Hematologic reactions to carbonic anhydrase inhibitors.
    American journal of ophthalmology, 1985, Jul-15, Volume: 100, Issue:1

    Topics: Acetazolamide; Agranulocytosis; Anemia, Aplastic; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Glaucoma; Humans; Leukopenia; Methazolamide; Pancytopenia; Thrombocytopenia

1985
The anticonvulsant effect of carbonic anhydrase inhibitors in mice--a noradrenergic mechanism of action.
    European journal of pharmacology, 1973, Volume: 21, Issue:3

    Topics: Acetazolamide; Amino Acids; Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Carboxy-Lyases; Dichlorphenamide; Dihydroxyphenylalanine; Disulfiram; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Electroshock; Female; Hydrazines; Methazolamide; Methyldopa; Mice; Monoamine Oxidase Inhibitors; Picolinic Acids; Reserpine

1973
A novel assay for erythrocyte carbonic anhydrase and certain sulfonamide drugs employing spin-labels.
    Pharmacology, 1972, Volume: 8, Issue:4

    Topics: Acetazolamide; Animals; Carbonic Anhydrases; Cattle; Chemical Phenomena; Chemistry; Dichlorphenamide; Electron Spin Resonance Spectroscopy; Erythrocytes; Humans; In Vitro Techniques; Methods; Spectrophotometry; Sulfonamides

1972
Reformation of the anterior chamber of the eye.
    Southern medical journal, 1968, Volume: 61, Issue:8

    Topics: Acetazolamide; Anterior Chamber; Anxiety; Aqueous Humor; Cataract Extraction; Corneal Injuries; Dichlorphenamide; Glaucoma; Glycerol; Humans; Hypnotics and Sedatives; Intraocular Pressure; Suture Techniques; Tranquilizing Agents; Urea; Wound Healing

1968
Inhibition of carbonic anhydrase in Neisseria: effects on enzyme activity and growth.
    Molecular pharmacology, 1967, Volume: 3, Issue:2

    Topics: Acetazolamide; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chlorothiazide; Dichlorphenamide; Erythrocytes; Methazolamide; Neisseria; Sulfadiazine; Sulfanilamides

1967
Simple assay for determination of carbonic anhydrase activity.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:7

    Topics: Acetazolamide; Animals; Brain; Carbon Dioxide; Carbon Isotopes; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dichlorphenamide; Dogs; Erythrocytes; Kidney; Methods; Rats

1969
[Blood acidosis and intraocular hypotension].
    Klinische Monatsblatter fur Augenheilkunde, 1972, Volume: 160, Issue:1

    Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Animals; Aqueous Humor; Ascorbic Acid; Bicarbonates; Calcium Chloride; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Glaucoma; Humans; Hydrogen-Ion Concentration; Intraocular Pressure; Rabbits; Time Factors

1972
Modern problems in glaucoma.
    Transactions of the ophthalmological societies of the United Kingdom, 1971, Volume: 91

    Topics: Acetazolamide; Acute Disease; Aged; Bicarbonates; Chronic Disease; Ciliary Body; Dichlorphenamide; Echothiophate Iodide; Glaucoma; Humans; Physostigmine; Pilocarpine; Sympathomimetics

1971
[Ocular hypotonic effect of hematic acidifying agents: carbonic anhydrase inhibitors].
    Bollettino d'oculistica, 1970, Volume: 49, Issue:9

    Topics: Acetazolamide; Animals; Aqueous Humor; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Glaucoma; Humans; Hydrogen-Ion Concentration; Intraocular Pressure; Rabbits

1970
Effects of systemically administered drugs on intraocular pressure in rabbits.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Acetazolamide; Amphetamine; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Carotid Arteries; Chlordiazepoxide; Chlorothiazide; Chlorpromazine; Depression, Chemical; Dichlorphenamide; Female; Glycerol; Guanethidine; Hexamethonium Compounds; Imipramine; Intraocular Pressure; Iproniazid; Male; Mannitol; Phenoxybenzamine; Phenylbutazone; Pilocarpine; Pyridines; Rabbits; Stimulation, Chemical; Urea

1970
[Treatment of open angle glaucoma (synonym: chronic simple glaucoma)].
    Annales d'oculistique, 1968, Volume: 201, Issue:1

    Topics: Acetazolamide; Acetylcholine; Carbonic Anhydrase Inhibitors; Chronic Disease; Dichlorphenamide; Echothiophate Iodide; Epinephrine; Glaucoma; Humans; Isoflurophate; Miotics; Physostigmine; Pilocarpine

1968
Inhibition of the morphogenesis of the otoliths in the chick embryo in the presence of carbonic anhydrase inhibitors.
    Experientia, 1968, Aug-15, Volume: 24, Issue:8

    Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Calcium Carbonate; Calcium Isotopes; Carbonic Anhydrase Inhibitors; Chick Embryo; Depression, Chemical; Dichlorphenamide; Ear, Inner; Morphogenesis; Sensory Receptor Cells; Sulfonamides

1968
Carbonic anhydrase inhibitors and osmotic agents in glaucoma. Carbonic anhydrase inhibitors.
    The British journal of ophthalmology, 1968, Volume: 52, Issue:8

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Glaucoma; Humans; Intraocular Pressure; Methazolamide

1968
The water-loading test in rabbits. A method to detect potential ocular hypotensive drugs.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1969, Volume: 82, Issue:3

    Topics: Acetazolamide; Animals; Atropine; Carbachol; Dichlorphenamide; Epinephrine; Glaucoma; Hexamethonium Compounds; Intraocular Pressure; Isoproterenol; Methods; Phenoxybenzamine; Physostigmine; Pilocarpine; Propranolol; Rabbits; Time Factors; Tonometry, Ocular

1969
Oral drugs for glaucoma.
    Drug and therapeutics bulletin, 1965, Dec-10, Volume: 3, Issue:25

    Topics: Acetazolamide; Dichlorphenamide; Glaucoma; Humans

1965
Effect of bendroflumethiazide on distal nephron transport of sodium, potassium and chloride.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 151, Issue:2

    Topics: Absorption; Acetazolamide; Animals; Bendroflumethiazide; Biological Transport; Blood; Carbonic Anhydrase Inhibitors; Chlorides; Creatine; Dichlorphenamide; Dogs; In Vitro Techniques; Kidney Tubules; Mannitol; Natriuresis; Potassium; Sodium; Sulfates; Urine

1966
[Side effects of opthalmic drugs].
    Ganka. Ophthalmology, 1966, Volume: 8, Issue:11

    Topics: Acetazolamide; Adolescent; Adult; Aged; Cortisone; Dichlorphenamide; Epinephrine; Eye Diseases; Female; Glaucoma; Humans; Male; Sulfanilamides

1966
Diuretics found effective against meningococci?
    JAMA, 1967, Feb-13, Volume: 199, Issue:7

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Chlorothiazide; Dichlorphenamide; Humans; Hydrochlorothiazide; Methazolamide; Neisseria; Sulfadiazine; Sulfanilamides; Sulfonamides

1967
A role for carbonic anhydrase in de novo fatty acid synthesis in liver.
    Annals of the New York Academy of Sciences, 1984, Volume: 429

    Topics: Acetates; Acetazolamide; Acetic Acid; Animals; Carbonic Anhydrases; Dichlorphenamide; Fatty Acids; Liver; Lizards

1984
Metabolic acidosis induced by carbonic anhydrase inhibitors and salicylates in patients with normal renal function.
    British medical journal (Clinical research ed.), 1984, Aug-11, Volume: 289, Issue:6441

    Topics: Acetazolamide; Acidosis; Adult; Arthritis; Aspirin; Carbonic Anhydrase Inhibitors; Child; Dichlorphenamide; Drug Interactions; Drug Therapy, Combination; Female; Glaucoma; Humans; Male; Salicylates

1984
Dichlorphenamide as a diuretic agent.
    The American journal of the medical sciences, 1958, Volume: 235, Issue:2

    Topics: Acetazolamide; Dichlorphenamide; Diuretics; Heart Failure

1958
Effects of acetazolamide, chlorothiazide, and dichlorphenamide on electrolyte excretion in the alligator.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1957, Volume: 96, Issue:3

    Topics: Acetazolamide; Alligators and Crocodiles; Animals; Biological Transport; Body Fluids; Chlorothiazide; Dichlorphenamide; Electrolytes; Humans

1957
Effect of dichlorphenamide on the intraocular pressure of humans.
    A.M.A. archives of ophthalmology, 1958, Volume: 60, Issue:3

    Topics: Acetazolamide; Dichlorphenamide; Eye Diseases; Glaucoma; Intraocular Pressure; Tonometry, Ocular

1958
Evaluation of dichlorphenamide as an ocular hypotensive agent.
    A.M.A. archives of ophthalmology, 1958, Volume: 60, Issue:6

    Topics: Acetazolamide; Antihypertensive Agents; Dichlorphenamide; Eye; Glaucoma; Humans; Intraocular Pressure; Tonometry, Ocular

1958
The treatment of respiratory acidosis with a potent carbonic anhydrase inhibitor (dichlorphenamide).
    The American journal of the medical sciences, 1958, Volume: 236, Issue:5

    Topics: Acetazolamide; Acidosis; Acidosis, Respiratory; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Humans

1958
Clinical comparison of dichlorphenamide, chlorothiazide and sulocarbilate with acetazolamide in control of glaucoma.
    American journal of ophthalmology, 1959, Volume: 47, Issue:2

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Chlorothiazide; Dichlorphenamide; Glaucoma; Humans

1959
[Pharmacology and administration of antiglaucoma medication].
    Archivos de oftalmologia de Buenos Aires, 1963, Volume: 38

    Topics: Acetazolamide; Dichlorphenamide; Epinephrine; Glaucoma; Humans; Miotics; Parasympathomimetics

1963
[The diuretic inhibitors of carbonic anhydrase].
    Acta cardiologica, 1962, Volume: 17

    Topics: Acetazolamide; Acidosis; Carbonic Anhydrases; Dichlorphenamide; Diuretics; Humans

1962
FIXED, DILATED PUPIL, IRIS ATROPHY AND SECONDARY GLAUCOMA.
    American journal of ophthalmology, 1963, Volume: 56

    Topics: Acetazolamide; Atrophy; Atropine; Corneal Transplantation; Dichlorphenamide; Glaucoma; Humans; Iris; Iris Diseases; Keratoconus; Mydriasis; Mydriatics; Postoperative Complications; Pupil; Toxicology

1963
[EXPERIMENTAL DETERMINATION OF ANTICONVULSANT PROPERTIES OF DICHLORPHENAMIDE BY ELECTROENCEPHALOGRAPHIC STUDY UNDER INTERMITTENT PHOTIC STIMULATION].
    Annales medicales de Nancy, 1963, Volume: 2

    Topics: Acetazolamide; Adolescent; Alcoholism; Anticonvulsants; Anxiety; Bemegride; Dichlorphenamide; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Humans; Intellectual Disability; Photic Stimulation; Photosensitivity Disorders; Radiotherapy; Seizures

1963
[RENAL CARBONIC ANHYDRASE: ITS PHYSIOLOGICAL ACTION; ITS INHIBITORS].
    La Revue du praticien, 1963, Dec-01, Volume: 13

    Topics: Acetazolamide; Acidosis; Ammonia; Carbonic Anhydrases; Chlorothiazide; Chlorthalidone; Dichlorphenamide; Diuretics; Edema; Enzyme Inhibitors; Hydrochlorothiazide; Hypokalemia; Kidney; Physiology; Pulmonary Heart Disease; Respiratory Insufficiency

1963
[THE NEW ANTIEPILEPTIC AGENTS].
    La Revue du praticien, 1963, Dec-09, Volume: 13

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Amitriptyline; Anticonvulsants; Chlordiazepoxide; Dichlorphenamide; Epilepsy; Hydantoins; Stilbenes; Sulfones

1963
[THE TASK OF THE GENERAL PRACTITIONER IN EMERGENCY OPHTHALMOLOGIC WORK].
    Rassegna clinico-scientifica, 1964, Volume: 40

    Topics: Acetazolamide; Anti-Bacterial Agents; Benzimidazoles; Chloramphenicol; Dichlorphenamide; Epinephrine; Eye Burns; Eye Injuries; Family Practice; General Practice; General Practitioners; Idoxuridine; Leucomycins; Niacin; Nicotinic Acids; Novobiocin; Ointments; Ophthalmology; Penicillins; Phenylephrine; Scopolamine; Streptomycin; Tetracycline

1964
MEDICAL THERAPY ATTEMPTS IN MALIGNANT GLAUCOMA, REPORT OF THREE CASES.
    American journal of ophthalmology, 1964, Volume: 57

    Topics: Acetazolamide; Atropine; Chlorothiazide; Dichlorphenamide; Geriatrics; Glaucoma; Humans; Phenylephrine; Physostigmine; Pilocarpine; Scopolamine; Surgical Procedures, Operative; Urea

1964
DIURETIC THERAPY. I.
    American heart journal, 1964, Volume: 67

    Topics: Acetazolamide; Aminophylline; Ammonium Chloride; Dichlorphenamide; Diuretics; Heart Failure; Humans; Imidazoles; Lysine; Mannitol; Methazolamide; Pharmacology; Theobromine; Toxicology; Urea

1964
THE RESPIRATORY ACTION OF DICHLORPHENAMIDE.
    British journal of pharmacology and chemotherapy, 1964, Volume: 22

    Topics: Acetazolamide; Acidosis; Biomedical Research; Blood Gas Analysis; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Cell Respiration; Dichlorphenamide; Humans; Pharmacology; Respiration; Respiratory Insufficiency; Toxicology

1964
BILATERAL MALIGNANT GLAUCOMA. CASE REPORT OF SIMULTANEOUS MALIGNANT GLAUCOMA OCCURRING THREE YEARS AFTER GLAUCOMA SURGERY.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1964, Volume: 72

    Topics: Acetazolamide; Anterior Chamber; Aqueous Humor; Atropine; Dichlorphenamide; Echothiophate Iodide; Epinephrine; Eye; Geriatrics; Glaucoma; Humans; Mydriatics; Pilocarpine; Postoperative Complications; Sclera; Surgical Procedures, Operative

1964
[A CASE OF GLAUCOMA WITH LARGE DIURNAL VARIATION OF INTRAOCULAR PRESSURE].
    Nihon ganka kiyo, 1964, Volume: 15

    Topics: Acetazolamide; Circadian Rhythm; Dichlorphenamide; Drug Therapy; Eye Diseases; Glaucoma; Humans; Intraocular Pressure; Physiology; Tonometry, Ocular; Toxicology

1964
DIURETIC ACTION OF FUROSEMIDE.
    Archives of internal medicine, 1965, Volume: 115

    Topics: Acetazolamide; Bicarbonates; Biomedical Research; Blood Chemical Analysis; Carbonic Anhydrase Inhibitors; Chlorides; Chlorothiazide; Dichlorphenamide; Diuretics; Furosemide; Heart Failure; Hydrogen-Ion Concentration; Pharmacology; Polythiazide; Potassium; Sodium; Sodium, Dietary; Toxicology; Urine

1965
Acetazolamide prevents vacuolar myopathy in skeletal muscle of K(+) -depleted rats.
    British journal of pharmacology, 2008, Volume: 154, Issue:1

    Topics: Acetazolamide; Animals; Bendroflumethiazide; Carbonic Anhydrase Inhibitors; Cell Count; Dichlorphenamide; Diuretics; Electrolytes; Lactic Acid; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Diseases; Potassium Deficiency; Rats; Rats, Wistar; Vacuoles

2008
Biodegradable fumarate-based drug-delivery systems for ophthalmic applications.
    Journal of biomedical materials research. Part A, 2009, Mar-15, Volume: 88, Issue:4

    Topics: Acetazolamide; Animals; Antihypertensive Agents; Biocompatible Materials; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Dichlorphenamide; Diuretics; Drug Carriers; Drug Delivery Systems; Eye; Fumarates; Implants, Experimental; Molecular Structure; Polypropylenes; Rabbits; Timolol

2009