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dichlorophenyl-bis-triazolylpropanol and fluconazole

dichlorophenyl-bis-triazolylpropanol has been researched along with fluconazole in 3 studies

*Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS. [MeSH]

*Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS. [MeSH]

Compound Research Comparison

Studies
(dichlorophenyl-bis-triazolylpropanol)
Trials
(dichlorophenyl-bis-triazolylpropanol)
Recent Studies (post-2010)
(dichlorophenyl-bis-triazolylpropanol)
Studies
(fluconazole)
Trials
(fluconazole)
Recent Studies (post-2010) (fluconazole)
5019,3437213,664

Protein Interaction Comparison

ProteinTaxonomydichlorophenyl-bis-triazolylpropanol (IC50)fluconazole (IC50)
Lanosterol 14-alpha demethylaseCandida albicans SC53140.1296
Cytochrome P450 2C9 Homo sapiens (human)9.21
Sterol 14-alpha demethylaseTrypanosoma cruzi strain CL Brener0.88

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tam, KY; Wang, C; Yao, H; Zhang, SL1
Bigot, MC; Debruyne, D; Moulin, M; Ryckelynck, JP1
Ervine, CM; Houston, JB1

Other Studies

3 other study(ies) available for dichlorophenyl-bis-triazolylpropanol and fluconazole

ArticleYear
Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.
    Bioorganic & medicinal chemistry letters, 2014, Nov-01, Volume: 24, Issue:21

    Topics: Antifungal Agents; Binding Sites; Circular Dichroism; Fluconazole; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Protein Binding; Protein Conformation; Serum Albumin; Spectrometry, Fluorescence; Thermodynamics; Triazoles

2014
Determination of fluconazole in biological fluids by capillary column gas chromatography with a nitrogen detector.
    Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:6

    Topics: Antifungal Agents; Chromatography, Gas; Dialysis; Fluconazole; Humans; Nitrogen; Triazoles

1988
Disposition of azole antifungal agents. III. Binding of fluconazole and other azoles in rat liver.
    Pharmaceutical research, 1994, Volume: 11, Issue:7

    Topics: Adrenal Glands; Animals; Antifungal Agents; Azoles; Blood Proteins; Fluconazole; Kidney; Liver; Rats; Rats, Sprague-Dawley; Tissue Distribution; Triazoles

1994