dichlorodiphenyl dichloroethylene and flutamide

dichlorodiphenyl dichloroethylene has been researched along with flutamide in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (28.57)18.2507
2000's14 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Gray, LE; Kelce, WR; Lambright, CR; Roberts, KP1
Sohoni, P; Sumpter, JP1
Archibeque-Engle, S; Casanova, M; Fan, LQ; Heck, HA; Sar, M; You, L1
Archibeque-Engle, S; Bruce, JM; Casanova, M; Chan, SK; Corton, JC; Heck, H; You, L1
Cook, JC; Davis, LG; Frame, SR; O'Connor, JC1
Brenneman, KA; Heck, H; You, L1
Cooke, GM; Schrader, TJ1
Adams, MA; Brien, SE; Heaton, JP; Racz, WJ1
Holst, M; Ritzén, EM; Svechnikov, K1
Ashby, J; Deghenghi, R; Lefevre, PA; Wallis, N1
Baatrup, E; Junge, M1
Baatrup, E; Bayley, M; Junge, M1
Ashby, J; Lefevre, PA; Owens, W1
Frame, SR; Ladics, GS; O'Connor, JC1
Ashby, J; Lefevre, PA; Nellemann, C1
Choi, KS; Dong, MS; Han, SY; Kang, IH; Kil, KS; Kim, HS; Kim, IY; Kim, TS; Moon, HJ; Park, YI; Shin, JH1
Kawamura, S; Okuno, Y; Saito, K; Seki, T; Sukata, T; Sumida, K; Ueda, S; Yabushita, S; Yamada, T1
Veeramachaneni, DN1
Bars, R; Belluco, S; Elies, L; Friry-Santini, C; Pallen, C; Rouquié, D; Tinwell, H1
Han, SY; Kang, IH; Kang, TS; Ki, HY; Kim, SH; Kim, TS; Moon, HJ1
Chen, X; Hirano, M; Ishibashi, H; Kawai, YK; Kubota, A; Lee, JS1

Other Studies

21 other study(ies) available for dichlorodiphenyl dichloroethylene and flutamide

ArticleYear
Vinclozolin and p,p'-DDE alter androgen-dependent gene expression: in vivo confirmation of an androgen receptor-mediated mechanism.
    Toxicology and applied pharmacology, 1997, Volume: 142, Issue:1

    Topics: Androgen Antagonists; Androgen-Binding Protein; Animals; Clusterin; Dichlorodiphenyl Dichloroethylene; Drug Implants; Flutamide; Gene Expression Regulation; Glycoproteins; Male; Molecular Chaperones; Orchiectomy; Organ Size; Oxazoles; Prostate; Prostatein; Rats; Rats, Sprague-Dawley; Receptors, Androgen; RNA, Messenger; Secretoglobins; Seminal Vesicles; Testosterone; Uteroglobin

1997
Several environmental oestrogens are also anti-androgens.
    The Journal of endocrinology, 1998, Volume: 158, Issue:3

    Topics: Androgen Antagonists; Androgens; Benzhydryl Compounds; Biological Assay; DDT; Dichlorodiphenyl Dichloroethylene; Diethylstilbestrol; Environmental Pollution; Estrogen Antagonists; Estrogens; Flutamide; Fungicides, Industrial; Gene Expression; Hormones; Humans; Oxazoles; Pesticides; Phenols; Receptors, Androgen; Receptors, Estrogen; Saccharomyces cerevisiae; Xenobiotics

1998
Impaired male sexual development in perinatal Sprague-Dawley and Long-Evans hooded rats exposed in utero and lactationally to p,p'-DDE.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 45, Issue:2

    Topics: Animals; Animals, Suckling; Brain; Dichlorodiphenyl Dichloroethylene; Female; Flutamide; Genitalia, Male; Insecticides; Liver; Male; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Androgen; Testosterone

1998
Modulation of testosterone-metabolizing hepatic cytochrome P-450 enzymes in developing Sprague-Dawley rats following in utero exposure to p,p'-DDE.
    Toxicology and applied pharmacology, 1999, Jul-15, Volume: 158, Issue:2

    Topics: Age Factors; Androgen Antagonists; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Dichlorodiphenyl Dichloroethylene; Female; Flutamide; Immunoblotting; Liver; Male; Maternal-Fetal Exchange; Microsomes, Liver; Pregnancy; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Time Factors

1999
Detection of the environmental antiandrogen p,p-DDE in CD and long-evans rats using a tier I screening battery and a Hershberger assay.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 51, Issue:1

    Topics: Animals; Body Weight; Dichlorodiphenyl Dichloroethylene; Disease Models, Animal; Flutamide; Gonadal Steroid Hormones; Insecticides; Liver; Male; Orchiectomy; Organ Size; Prostate; Rats; Rats, Long-Evans; Saccharomyces cerevisiae; Seminal Vesicles; Testis; Toxicity Tests; Transcriptional Activation

1999
In utero exposure to antiandrogens alters the responsiveness of the prostate to p,p'-DDE in adult rats and may induce prostatic inflammation.
    Toxicology and applied pharmacology, 1999, Dec-15, Volume: 161, Issue:3

    Topics: Adipose Tissue; Administration, Oral; Androgen Antagonists; Animals; Blotting, Northern; Clusterin; Dichlorodiphenyl Dichloroethylene; Female; Flutamide; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycoproteins; Liver; Luteinizing Hormone; Male; Molecular Chaperones; Organ Size; Peptide Fragments; Pregnancy; Prenatal Exposure Delayed Effects; Prostate; Prostatitis; Rats; Rats, Long-Evans; RNA, Messenger; Testosterone

1999
Examination of selected food additives and organochlorine food contaminants for androgenic activity in vitro.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 53, Issue:2

    Topics: Adenocarcinoma; Androgens; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Survival; Chlordecone; Dichlorodiphenyl Dichloroethylene; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Food Additives; Food Contamination; Hexachlorocyclohexane; Hormone Antagonists; Humans; Insecticides; Luciferases; Male; Pesticide Residues; Polychlorinated Dibenzodioxins; Prostatic Neoplasms; Receptors, Androgen; Toxaphene; Transfection; Tumor Cells, Cultured

2000
Effects of an environmental anti-androgen on erectile function in an animal penile erection model.
    The Journal of urology, 2000, Volume: 163, Issue:4

    Topics: Androgen Antagonists; Animals; Castration; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Environmental Pollutants; Erectile Dysfunction; Flutamide; Insecticides; Male; Penile Erection; Rats; Rats, Wistar; Testosterone; Time Factors

2000
Androgen and estrogen stimulation of ornithine decarboxylase activity in mouse kidney.
    The Journal of steroid biochemistry and molecular biology, 2000, Dec-31, Volume: 75, Issue:4-5

    Topics: Androgen Antagonists; Animals; Cyproterone Acetate; Dichlorodiphenyl Dichloroethylene; Dihydrotestosterone; Estradiol; Female; Flutamide; Kidney; Mice; Mice, Inbred CBA; Ornithine Decarboxylase; Oxazoles; Spironolactone; Testosterone

2000
Replacement of surgical castration by GnRH-inhibition or Leydig cell ablation in the male rat Hershberger antiandrogen assay.
    Regulatory toxicology and pharmacology : RTP, 2001, Volume: 34, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Animals; Body Weight; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Enzyme Inhibitors; Finasteride; Flutamide; Gonadotropin-Releasing Hormone; Hormone Antagonists; Hormone Replacement Therapy; Insecticides; Leydig Cells; Male; Mesylates; Oligopeptides; Orchiectomy; Organ Size; Rats; Rats, Inbred Strains

2001
Antiandrogenic pesticides disrupt sexual characteristics in the adult male guppy Poecilia reticulata.
    Environmental health perspectives, 2001, Volume: 109, Issue:10

    Topics: Animals; Dichlorodiphenyl Dichloroethylene; Flutamide; Insecticides; Male; Pigmentation; Poecilia; Reproduction; Sex Characteristics; Sexual Behavior, Animal; Sperm Count

2001
Exposure of juvenile guppies to three antiandrogens causes demasculinization and a reduced sperm count in adult males.
    Aquatic toxicology (Amsterdam, Netherlands), 2002, Volume: 56, Issue:4

    Topics: Androgen Antagonists; Animals; Dichlorodiphenyl Dichloroethylene; Female; Flutamide; Fungicides, Industrial; Insecticides; Male; Oxazoles; Poecilia; Reproduction; Sex Characteristics; Sex Ratio; Sexual Behavior, Animal; Sexual Maturation; Sperm Count; Spermatogenesis

2002
Concept evaluation: androgen-stimulated immature intact male rats as an assay for antiandrogens.
    Regulatory toxicology and pharmacology : RTP, 2002, Volume: 35, Issue:2 Pt 1

    Topics: Administration, Oral; Androgen Antagonists; Androgens; Animals; Clinical Protocols; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Drug Therapy, Combination; Flutamide; Genitalia, Male; Male; Methyltestosterone; Rats; Rats, Inbred Strains; Sexual Maturation

2002
Evaluation of a 15-day screening assay using intact male rats for identifying antiandrogens.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 69, Issue:1

    Topics: Androgen Antagonists; Androgens; Animals; Body Weight; Cyproterone Acetate; Dichlorodiphenyl Dichloroethylene; Diethylhexyl Phthalate; Drug Evaluation, Preclinical; Flutamide; Immune System; Linuron; Male; Organ Size; Oxazoles; Rats; Rats, Sprague-Dawley; Thyroid Gland

2002
Comparison of prostate gene expression and tissue weight changes as monitors of antiandrogen activity in GNRH-inhibited rats.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2003, Volume: 68, Issue:4

    Topics: Androgen Antagonists; Androgen-Binding Protein; Animals; Biomarkers; Body Weight; Clusterin; Dichlorodiphenyl Dichloroethylene; Flutamide; Gene Expression; Glycoproteins; Gonadotropin-Releasing Hormone; Male; Molecular Chaperones; Oligopeptides; Orchiectomy; Organ Size; Ornithine Decarboxylase; Prostate; Prostatein; Rats; Rats, Sprague-Dawley; Secretoglobins; Testosterone Propionate; Uteroglobin

2003
Comparison of anti-androgenic activity of flutamide, vinclozolin, procymidone, linuron, and p, p'-DDE in rodent 10-day Hershberger assay.
    Toxicology, 2004, Jul-01, Volume: 199, Issue:2-3

    Topics: Administration, Oral; Androgen Antagonists; Animals; Bridged Bicyclo Compounds; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Drug Interactions; Flutamide; Genitalia, Male; Injections, Subcutaneous; Linuron; Luteinizing Hormone; Male; Orchiectomy; Organ Size; Oxazoles; Rats; Rats, Sprague-Dawley; Testosterone

2004
Functional genomics may allow accurate categorization of the benzimidazole fungicide benomyl: lack of ability to act via steroid-receptor-mediated mechanisms.
    Toxicology and applied pharmacology, 2005, May-15, Volume: 205, Issue:1

    Topics: Administration, Oral; Animals; Benomyl; Benzimidazoles; Biological Assay; Carbamates; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Down-Regulation; Estrogen Receptor alpha; Ethinyl Estradiol; Female; Flutamide; Fungicides, Industrial; Gene Expression; Gene Expression Profiling; Genes, Reporter; Genomics; HeLa Cells; Humans; Luciferases; Male; Microtubules; Orchiectomy; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Testosterone Propionate; Uterus

2005
Germ cell atypia in undescended testes hinges on the aetiology of cryptorchidism but not the abdominal location per se.
    International journal of andrology, 2006, Volume: 29, Issue:1

    Topics: Abdomen; Androgen Antagonists; Animals; Carcinoma in Situ; Cryptorchidism; Dichlorodiphenyl Dichloroethylene; Estradiol; Female; Flutamide; Germ Cells; Male; Phenols; Pregnancy; Rabbits; Testicular Neoplasms; Testis

2006
Evaluation of the antiandrogenic effects of flutamide, DDE, and linuron in the weanling rat assay using organ weight, histopathological, and proteomic approaches.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 100, Issue:1

    Topics: Adrenal Glands; Androgen Antagonists; Animals; Biomarkers, Pharmacological; Body Weight; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Endocrine Disruptors; Epididymis; Flutamide; Genitalia, Male; Kidney; L-Amino Acid Oxidase; Linuron; Liver; Male; Organ Size; Prostate; Proteomics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Seminal Vesicles; Testis; Testosterone Propionate; Time Factors; Toxicity Tests; Weaning

2007
OECD validation of phase 3 Hershberger assay in Korea using surgically castrated male rats with coded chemicals.
    Journal of applied toxicology : JAT, 2009, Volume: 29, Issue:4

    Topics: Anabolic Agents; Androgen Antagonists; Androgens; Animals; Biological Assay; Body Weight; Dichlorodiphenyl Dichloroethylene; Endocrine Disruptors; Female; Flutamide; Follow-Up Studies; Insecticides; Korea; Linuron; Male; Orchiectomy; Organ Size; Pregnancy; Rats; Rats, Sprague-Dawley; Reproduction; Testosterone; Trenbolone Acetate

2009
Efficient in vivo and in silico assessments of antiandrogenic potential in zebrafish.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2023, Volume: 264

    Topics: Animals; Dichlorodiphenyl Dichloroethylene; Fenitrothion; Flutamide; Linuron; Zebrafish

2023