dichloroacetic acid has been researched along with trichloroacetic acid in 138 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (7.25) | 18.7374 |
| 1990's | 49 (35.51) | 18.2507 |
| 2000's | 37 (26.81) | 29.6817 |
| 2010's | 35 (25.36) | 24.3611 |
| 2020's | 7 (5.07) | 2.80 |
| Authors | Studies |
|---|---|
| Dunn, WJ; Grigoras, S; Koehler, MG | 1 |
| Caron, G; Ermondi, G | 1 |
| Escudero, AG; González, MP; Pérez-Garrido, A | 1 |
| Ebina, S; Nagai, Y | 1 |
| Bull, RJ; Eyre, RJ; Stevens, DK | 1 |
| Clemens, M; Schöler, HF | 1 |
| Davis, ME | 3 |
| Berndt, WO; Davis, ME | 1 |
| Bull, RJ; Larson, JL | 2 |
| Hatch, KD | 1 |
| Ansari, GA; Bhat, HK; Campbell, GA; Kanz, MF | 1 |
| Bull, RJ; Lansing, AJ; Larson, JL; Nelson, MA; Sanchez, IM | 1 |
| Bull, RJ; Sanchez, IM | 1 |
| Bull, RJ; Nelson, MA; Sanchez, IM; Sylvester, SR | 1 |
| Exon, JH; Koller, LD; Mather, GG | 1 |
| Bull, RJ; Lansing, AJ; Nelson, MA; Sanchez, IM; Springer, DL | 1 |
| Daniel, FB; DeAngelo, AB; McMillan, L; Savage, RE; Wernsing, P | 1 |
| Herren-Freund, SL; Khoury, MD; Olson, G; Pereira, MA | 1 |
| Lynch, PJ | 1 |
| Calabrese, EJ; Leonard, DA | 1 |
| Dierickx, PJ | 1 |
| Hathway, DE | 1 |
| Black, RK; Gearhart, JM; Hoover, DK; Jepson, GW; Mahle, DA; McCafferty, JD | 1 |
| DeAngelo, AB; Ferreira-Gonzalez, A; Garrett, CT; Nasim, S | 1 |
| Austin, EW; Bull, RJ; Larson, JL; Okita, JR; Okita, RT | 1 |
| Bantle, JA; Fort, DJ; Hull, M; Rayburn, JR; Stover, EL | 1 |
| Bull, RJ; Parker, JC; Templin, MV | 1 |
| Bruschi, SA; Bull, RJ | 1 |
| Pereira, MA; Phelps, JB | 1 |
| Bull, RJ; Stevens, DK; Xu, G | 1 |
| Benane, SG; Blackman, CF; House, DE | 1 |
| Paul, CH; Royappa, AT | 1 |
| Langonné, I; Sabaté, JP; Saillenfait, AM | 1 |
| Pereira, MA | 1 |
| Abbas, R; Fisher, JW; Lipscomb, JC; Moghaddam, AP; Stavrou, S | 1 |
| Abbas, RR; Fisher, JW; Kidney, JK; Seckel, CS | 1 |
| Kramer, PM; Li, K; Pereira, MA; Tao, L | 1 |
| Kramer, PM; Li, K; Pereira, MA | 1 |
| Bull, RJ; Stauber, AJ | 1 |
| Abbas, R; Bishop, CT; Brashear, WT | 1 |
| Austin, EW; Bull, RJ | 1 |
| Abbas, R; Fisher, JW | 1 |
| Erb, F; Giller, S; Le Curieux, F; Marzin, D | 1 |
| Doerr, CL; Harrington-Brock, K; Moore, MM | 1 |
| Borrull, F; Calull, M; Colom, A; Farré, J; Martínez, D; Ruana, J | 1 |
| Bull, RJ; Stauber, AJ; Thrall, BD | 1 |
| Ge, R; Kramer, PM; Pereira, MA; Tao, L | 1 |
| Frazier, JM; Toxopeus, C | 1 |
| Bull, RJ; Gonzalez-Leon, A; Merdink, JL; Schultz, IR | 2 |
| Dekant, W; Friedewald, M; Lederer, E; Pähler, A; Parker, J; Völkel, W | 1 |
| Borrull, F; Calull, M; Martínez, D | 1 |
| Burton, GA; Fisher, JW; Greenberg, MS | 1 |
| Haltmeier, P; Kim, H; Klotz, JB; Weisel, CP | 1 |
| Boorman, GA | 1 |
| Bull, RJ; Merdink, JL; Parker, JC; Stenner, RD; Stevens, DK | 1 |
| Galceran, MT; Santos, FJ; Sarrión, MN | 1 |
| Henderson, GN; James, MO; Stacpoole, PW; Yan, Z | 1 |
| Kramer, PM; Pereira, MA; Tao, L; Xie, M; Yang, S | 2 |
| Bull, RJ | 1 |
| Chen, CW | 1 |
| Bull, RJ; Merdink, JL; Schultz, IR | 1 |
| Ellis, DA; Fineberg, NA; Hanson, ML; Mabury, SA; Muir, DC; Shahid, T; Sibley, PK; Solomon, KR | 1 |
| Kurtz, DT; McMillan, JM; Walgren, JE | 1 |
| Abbt-Braun, G; Chiang, PC; Frimmel, FH; Gremm, TJ; Ko, YW | 1 |
| Ge, R; Kramer, PM; Pereira, MA; Tao, L; Yang, S | 1 |
| Conran, PB; Kramer, PM; Pereira, MA; Tao, L | 1 |
| Bull, RJ; Cheng, RS; Lingohr, MK; Orner, GA; Sasser, LB; Stauber, AJ; Stillwell, L; Thrall, BD | 1 |
| Ding, MY; Haddad, PR; Hasebe, K; Helaleh, MI; Hu, W; Mori, M; Tanaka, K; Taoda, H; Xu, Q | 1 |
| Hassoun, EA; Ray, S | 1 |
| Krishnan, K; St-Pierre, A; Tardif, R | 1 |
| Kramer, PM; Li, Y; Pereira, MA; Tao, L; Wang, W | 1 |
| Bull, RJ; Lei, XC; Sasser, LB | 1 |
| Cattley, RC; Corton, JC; Dunn, CS; Howroyd, P; Laughter, AR; Swanson, CL | 1 |
| Bartlett, MG; Bruckner, JV; Delinsky, AD | 1 |
| Wang, YH; Wong, PK | 1 |
| Kurtz, DT; McMillan, JM; Walgren, JL | 1 |
| Kramer, PK; Li, L; Pereira, MA; Tao, L; Wang, W | 1 |
| Deng, RS; Qi, R; Wang, KP; Yang, M; Zhang, Y | 1 |
| Barra, R; Bootsma, HA; Johnston, AE; Jones, KC; Martin, JW; Muir, DC; Scott, BF; Spencer, C | 1 |
| Chiu, WA; Clewell, HJ; Hack, CE; Jay Zhao, Q | 1 |
| Caldwell, JC; Keshava, N | 1 |
| Heng, ZC; Yang, Y | 1 |
| Bull, RJ; Hu, M; Merdink, JL; Parker, JC; Robison, LM; Stevens, DK | 1 |
| Dey, S; Hassoun, EA | 1 |
| Corton, JC | 1 |
| Kim, J | 1 |
| Chang, SN; Chen, CY; Wang, GS | 1 |
| Collins, LB; Kim, D; Kim, S; Pollack, GM; Rusyn, I | 1 |
| Ball, LM; Boysen, G; Bradford, BU; Collins, LB; Gold, A; Kim, S; Rusyn, I; Swenberg, JA | 1 |
| Cearfoss, J; Hassoun, EA; Spildener, J | 1 |
| Carleer, R; Dupae, J; Newman, L; Taghavi, S; Truyens, S; van der Lelie, D; Vangronsveld, J; Weyens, N | 1 |
| Dringen, R; Rohwedder, A; Schmidt, MM | 1 |
| Sanghvi, YS; Tram, K; Yan, H | 1 |
| Cardador, MJ; Gallego, M | 2 |
| Chow, CW; Liu, W; Wang, D; Zhao, Y | 1 |
| Al-Dieri, A; Hassoun, EA | 1 |
| Tang, S; Wang, XM; Xie, YF; Yang, HW | 1 |
| Gan, W; Guo, W; He, Y; Liang, Y; Liu, W; Liu, Y; Mo, J; Yang, X | 1 |
| Al-Hassan, N; Cearfoss, J; Hassoun, EA; Krispinsky, S; Liu, MC; Musser, B | 1 |
| Fang, ZZ; Gonzalez, FJ; Idle, JR; Krausz, KW; Li, F; Qu, A; Tanaka, N | 1 |
| Abdullah, AM; Hussona, Sel-D | 1 |
| Her, GR; Hung, SH | 1 |
| Liu, B; Reckhow, DA | 1 |
| Arnold, WA; Zeng, T | 1 |
| Al-Hassan, N; Brown, M; Cearfoss, J; Hassoun, E; Heimberger, K; Liu, MC; Mamada, S | 1 |
| Lu, Y; Sun, L; Sun, X; Wang, K; Zhang, J | 1 |
| An, W; Li, H; Pan, S; Su, M; Yang, M; Zhang, J | 1 |
| He, MJ; Huang, X; Huang, YH; Lu, WQ; Lu, ZW; Wang, L; Wang, P; Wang, YX; Zeng, Q | 1 |
| Ball, LM; Bodnar, WM; Bradford, BU; Collins, LB; Gold, A; Kosyk, O; Rusyn, I; Shymonyak, S; Uehara, T; Yoo, HS | 2 |
| Mao, YQ; Tang, S; Wang, XM; Xie, YF; Yang, HW; Zhao, Y | 1 |
| Hassoun, E; Mettling, C | 1 |
| Chen, L; Luo, X; Zhao, Y | 1 |
| Hao, W; Pan, Y; Wei, X | 1 |
| Tang, HL; Xie, YF | 1 |
| Hu, C; Liu, H; Qu, J; Zhang, D; Zhao, H | 1 |
| Faria, MA; Ferreira, IMPLVO; Mansilha, C; Melo, A; Pinto, E | 1 |
| Evans, A; Kaufman, JA; Meyer, A; Narotsky, MG; Rivera-Núñez, Z; Wright, JM | 1 |
| Dubé, J; Leduc, S; Legay, C; Levallois, P; Rodriguez, MJ | 1 |
| Ai, SH; Chen, C; Chen, YJ; Duan, P; Huang, LL; Huang, Z; Li, J; Liu, C; Lu, WQ; Meng, TQ; Pan, A; Sun, L; Sun, Y; Wan, ZZ; Wang, L; Wang, Q; Wang, YX | 1 |
| da Silva Faria, MC; Franco, ES; Maia, LFO; Mourão, AO; Pádua, VL; Rodrigues, JL; Rodriguez, M; Silva, DF; Torres, TS | 1 |
| Hao, W; Hou, X; Meng, Q; Pan, Y; Shang, L; Wei, X; Yang, X | 1 |
| Chen, Z; Chu, W; Kang, J; Shen, J; Wang, B; Zhang, X; Zhao, S; Zhou, Y | 1 |
| Guo, AJ; Niu, YJ; Wei, N; Zhang, R; Zhang, SH | 1 |
| Chen, PP; Cui, FP; Deng, YL; Li, YF; Liu, C; Lu, TT; Lu, WQ; Luo, Q; Miao, Y; Shi, T; Yao, W; Yuan, XQ; Zeng, JY; Zeng, Q; Zhang, M | 1 |
| Fang, L; Jiang, R; Liao, P; Wu, G; Zhang, T | 1 |
| Deng, YL; Li, CR; Li, YJ; Liu, AX; Liu, C; Liu, XY; Miao, Y; Wu, Y; Zeng, JY; Zeng, Q; Zhang, M; Zhu, JQ | 1 |
| Bado-Nilles, A; Ciccia, T; Ciffroy, P; Lafay, L; Pandard, P; Urien, N | 1 |
| Liu, J; Shi, Y; Wan, Y; Wang, D; Xia, W; Yang, Z; Zhao, X | 1 |
6 review(s) available for dichloroacetic acid and trichloroacetic acid
| Article | Year |
|---|---|
Condylomata acuminata (anogenital warts).
Topics: Adolescent; Adult; Age Factors; Anus Neoplasms; Child; Condylomata Acuminata; Cryosurgery; Dichloroacetic Acid; Electrosurgery; Female; Genital Neoplasms, Female; Humans; Infant, Newborn; Male; Podophyllin; Pregnancy; Pregnancy Complications, Neoplastic; Recurrence; Sex Factors; Sexually Transmitted Diseases; Trichloroacetic Acid | 1985 |
Drinking water disinfection byproducts: review and approach to toxicity evaluation.
Topics: Acetates; Animals; Chloroform; Dichloroacetic Acid; Disinfection; DNA Damage; Fishes; Humans; Hydrocarbons, Brominated; Mice; Ozone; Trichloroacetic Acid; Trihalomethanes; Water Supply | 1999 |
Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate.
Topics: Animals; Carcinogens, Environmental; Dichloroacetic Acid; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mutagens; Risk Assessment; Trichloroacetic Acid; Trichloroethylene | 2000 |
A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid.
Topics: Animals; Chloral Hydrate; Chromatography, Gas; Chromatography, Liquid; Dichloroacetic Acid; Humans; Mass Spectrometry; Trichloroacetic Acid; Trichloroethylene | 2005 |
Key issues in the modes of action and effects of trichloroethylene metabolites for liver and kidney tumorigenesis.
Topics: Animals; Carcinogenicity Tests; Chloral Hydrate; Cysteine; Dichloroacetic Acid; Environmental Pollutants; History, 21st Century; Humans; Kidney Neoplasms; Liver Neoplasms; Risk Assessment; Risk Factors; Signal Transduction; Trichloroacetic Acid; Trichloroethylene; United States | 2006 |
Evaluation of the role of peroxisome proliferator-activated receptor alpha (PPARalpha) in mouse liver tumor induction by trichloroethylene and metabolites.
Topics: Animals; Dichloroacetic Acid; Environmental Pollutants; Liver Neoplasms; Mice; Peroxisome Proliferator-Activated Receptors; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethylene | 2008 |
132 other study(ies) available for dichloroacetic acid and trichloroacetic acid
| Article | Year |
|---|---|
The role of solvent-accessible surface area in determining partition coefficients.
Topics: Diffusion; Solubility; Solvents; Structure-Activity Relationship | 1987 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.
Topics: Acetates; Chloroacetates; Computer Simulation; Data Collection; Hydrocarbons, Brominated; Models, Chemical; Models, Molecular; Mutagenicity Tests; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sensitivity and Specificity; Structure-Activity Relationship; Trichloroacetic Acid | 2008 |
Re-evaluation of turbidimetry of proteins by use of aromatic sulfonic acids and chloroacetic acids.
Topics: Albumins; Arylsulfonates; Dichloroacetic Acid; Hydrogen Bonding; Lactoglobulins; Nephelometry and Turbidimetry; Oxidation-Reduction; Photometry; Proteins; Salicylates; Trichloroacetic Acid | 1979 |
Adduction of hemoglobin and albumin in vivo by metabolites of trichloroethylene, trichloroacetate, and dichloroacetate in rats and mice.
Topics: Albumins; Amino Acids; Animals; Chromatography, Ion Exchange; Dichloroacetic Acid; Half-Life; Hemoglobins; Liver; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Trichloroacetic Acid; Trichloroethylene | 1992 |
[Halogenated organic compounds in swimming pool water].
Topics: Acetonitriles; Chloral Hydrate; Chloroform; Dichloroacetic Acid; Germany; Hydrocarbons, Halogenated; Swimming Pools; Trichloroacetic Acid; Trihalomethanes; Water Pollution | 1992 |
Dichloroacetic acid and trichloroacetic acid increase chloroform toxicity.
Topics: Alanine Transaminase; Animals; Blood Urea Nitrogen; Chloroform; Dichloroacetic Acid; Drinking; Drug Synergism; Eating; Female; Kidney; Liver; Male; Rats; Rats, Inbred Strains; Sex Characteristics; Trichloroacetic Acid | 1992 |
Sex differences in monochloroacetate pretreatment effects on chloroform toxicity in rats.
Topics: Acetates; Animals; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Chloroform; Dichloroacetic Acid; Female; Kidney Diseases; Kidney Function Tests; Liver Function Tests; Male; Potassium; Rats; Rats, Inbred Strains; Sex Characteristics; Sodium; Trichloroacetic Acid | 1992 |
Metabolism and lipoperoxidative activity of trichloroacetate and dichloroacetate in rats and mice.
Topics: Administration, Oral; Algorithms; Animals; Carbon Radioisotopes; Dichloroacetic Acid; Lipid Peroxidation; Lipid Peroxides; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred F344; Trichloroacetic Acid | 1992 |
Species differences in the metabolism of trichloroethylene to the carcinogenic metabolites trichloroacetate and dichloroacetate.
Topics: Administration, Oral; Algorithms; Animals; Dichloroacetic Acid; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains; Species Specificity; Trichloroacetic Acid; Trichloroethylene | 1992 |
Vulvovaginal human papillomavirus infections: clinical implications and management.
Topics: Adult; Condylomata Acuminata; Dichloroacetic Acid; Female; Humans; Interferon-alpha; Laser Therapy; Neoplasm Recurrence, Local; Papillomaviridae; Trichloroacetic Acid; Tumor Virus Infections; Vulvar Neoplasms | 1991 |
Ninety day toxicity study of chloroacetic acids in rats.
Topics: Acetates; Animals; Body Weight; Brain; Dichloroacetic Acid; Lethal Dose 50; Liver; Lung; Male; Rats; Rats, Inbred Strains; Testis; Trichloroacetic Acid | 1991 |
Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate.
Topics: Animals; Dichloroacetic Acid; Dose-Response Relationship, Drug; Hypertrophy; Lipofuscin; Liver Glycogen; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Mice, Inbred Strains; Organ Size; Precancerous Conditions; Trichloroacetic Acid | 1990 |
Early induction of reparative hyperplasia in the liver of B6C3F1 mice treated with dichloroacetate and trichloroacetate.
Topics: Analysis of Variance; Animals; Body Weight; Dichloroacetic Acid; Dose-Response Relationship, Drug; Female; Hyperplasia; Liver; Male; Mice; Organ Size; Random Allocation; Trichloroacetic Acid | 1990 |
Increased expression of c-myc and c-Ha-ras in dichloroacetate and trichloroacetate-induced liver tumors in B6C3F1 mice.
Topics: Animals; Dichloroacetic Acid; Gene Expression Regulation, Neoplastic; Genes, myc; Genes, ras; Liver Neoplasms, Experimental; Mice; Nucleic Acid Hybridization; Proto-Oncogenes; RNA, Messenger; RNA, Neoplasm; Trichloroacetic Acid | 1990 |
Subchronic 90 day toxicity of dichloroacetic and trichloroacetic acid in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Blood Proteins; Body Weight; Dichloroacetic Acid; Dose-Response Relationship, Drug; Drinking; Kidney; Liver; Male; Organ Size; Rats; Rats, Inbred Strains; Trichloroacetic Acid | 1990 |
Subacute toxicity of trichloroacetic acid in male and female rats.
Topics: Animals; Body Weight; Dichloroacetic Acid; Drinking; Eating; Female; Male; Osmolar Concentration; Rats; Rats, Inbred Strains; Sex Characteristics; Trichloroacetic Acid; Urine | 1990 |
Dichloroacetic acid and trichloroacetic acid-induced DNA strand breaks are independent of peroxisome proliferation.
Topics: Acetates; Animals; Dichloroacetic Acid; DNA; DNA Damage; Kinetics; Liver; Male; Mice; Microbodies; Microscopy, Electron; Organ Size; Oxidation-Reduction; Palmitoyl Coenzyme A; Trichloroacetic Acid | 1989 |
Species and strain sensitivity to the induction of peroxisome proliferation by chloroacetic acids.
Topics: Acetates; Animals; Body Weight; Carcinogens; Carnitine O-Acetyltransferase; Corn Oil; Dichloroacetic Acid; Electrophoresis, Polyacrylamide Gel; Liver; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microbodies; Organ Size; Pharmaceutical Vehicles; Rats; Rats, Inbred F344; Species Specificity; Trichloroacetic Acid; Water | 1989 |
The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver.
Topics: Acetates; Adenoma; Animals; Body Weight; Dichloroacetic Acid; Drug Synergism; Ethylnitrosourea; Liver Neoplasms, Experimental; Male; Mice; Organ Size; Phenobarbital; Trichloroacetic Acid; Trichloroethylene | 1987 |
Effect of chloroacetic acids on the kidneys.
Topics: Acetates; Acidosis; Animals; Dichloroacetic Acid; Disinfectants; Female; Glucose; Kidney; Lactates; Lactic Acid; Male; Rats; Rats, Inbred Strains; Trichloroacetic Acid; Water Supply | 1986 |
The effects of di- and trichloroacetic acid on sheep erythrocytes: an animal model with a glucose-6-phosphate dehydrogenase deficiency.
Topics: Acetates; Animals; Dichloroacetic Acid; Disease Models, Animal; Erythrocytes; Female; Glucosephosphate Dehydrogenase Deficiency; In Vitro Techniques; Methemoglobinemia; Sheep; Trichloroacetic Acid | 1984 |
In vitro binding of acetic acid and its chlorinated derivatives by the soluble glutathione S-transferases from rat liver.
Topics: Acetates; Acetic Acid; Animals; Dichloroacetic Acid; Glutathione Transferase; In Vitro Techniques; Isoenzymes; Liver; Protein Binding; Rats; Trichloroacetic Acid | 1984 |
Consideration of the evidence for mechanisms of 1,1,2-trichloroethylene metabolism, including new identification of its dichloroacetic acid and trichloroacetic acid metabolites in mice.
Topics: Acetates; Animals; Biotransformation; Dichloroacetic Acid; Male; Mice; Trichloroacetic Acid; Trichloroethylene | 1980 |
A partition coefficient determination method for nonvolatile chemicals in biological tissues.
Topics: Animals; Chemistry, Physical; Dichloroacetic Acid; Hexachlorocyclohexane; Male; Models, Chemical; Paraoxon; Parathion; Rats; Rats, Inbred F344; Solubility; Tetrachloroethylene; Trichloroacetic Acid | 1994 |
Ras oncogene activation during hepatocarcinogenesis in B6C3F1 male mice by dichloroacetic and trichloroacetic acids.
Topics: Animals; Base Sequence; Carcinogens; Dichloroacetic Acid; DNA Primers; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms, Experimental; Male; Mice; Molecular Sequence Data; Point Mutation; Trichloroacetic Acid | 1995 |
Modification of lipoperoxidative effects of dichloroacetate and trichloroacetate is associated with peroxisome proliferation.
Topics: Animals; Catalase; Cell Division; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dichloroacetic Acid; Lipid Peroxidation; Male; Mice; Microbodies; Mixed Function Oxygenases; Oxidoreductases; Trichloroacetic Acid | 1995 |
Evaluation of the developmental toxicity of trichloroethylene and detoxification metabolites using Xenopus.
Topics: Animals; Carbon Monoxide; Cyclohexanes; Cyclohexenes; Dichloroacetic Acid; Epoxide Hydrolases; Ethylene Chlorohydrin; In Vitro Techniques; Inactivation, Metabolic; Male; Mixed Function Oxygenases; Oxalates; Oxalic Acid; Rats; Rats, Sprague-Dawley; Teratogens; Trichloroacetic Acid; Trichloroethylene; Xenopus laevis | 1993 |
Relative formation of dichloroacetate and trichloroacetate from trichloroethylene in male B6C3F1 mice.
Topics: Animals; Biotransformation; Blood Proteins; Dichloroacetic Acid; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Protein Binding; Trichloroacetic Acid; Trichloroethylene | 1993 |
In vitro cytotoxicity of mono-, di-, and trichloroacetate and its modulation by hepatic peroxisome proliferation.
Topics: Acetates; Animals; Cells, Cultured; Clofibric Acid; Dichloroacetic Acid; Dose-Response Relationship, Drug; Glycolates; L-Lactate Dehydrogenase; Liver; Male; Mice; Microbodies; Oxidoreductases; Rats; Rats, Sprague-Dawley; Trichloroacetic Acid | 1993 |
Promotion by dichloroacetic acid and trichloroacetic acid of N-methyl-N-nitrosourea-initiated cancer in the liver of female B6C3F1 mice.
Topics: Animals; Body Weight; Carcinogens; Cocarcinogenesis; Dichloroacetic Acid; Drug Synergism; Eosine Yellowish-(YS); Female; Hematoxylin; Liver Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Staining and Labeling; Trichloroacetic Acid | 1996 |
Metabolism of bromodichloroacetate in B6C3F1 mice.
Topics: Acetates; Animals; Biotransformation; Dichloroacetic Acid; Feces; Male; Mice; Mice, Inbred Strains; Tissue Distribution; Trichloroacetic Acid | 1995 |
Effect of perchloroethylene and its metabolites on intercellular communication in clone 9 rat liver cells.
Topics: Analysis of Variance; Animals; Chloral Hydrate; Clone Cells; Dichloroacetic Acid; Ethylene Chlorohydrin; Gap Junctions; Liver; Male; Rats; Rats, Sprague-Dawley; Tetrachloroethylene; Trichloroacetic Acid; Water Pollutants | 1996 |
Acid binding and detritylation during oligonucleotide synthesis.
Topics: Acetates; Acetonitriles; Base Sequence; Dichloroacetic Acid; Kinetics; Methylene Chloride; Molecular Sequence Data; Oligodeoxyribonucleotides; Spectrum Analysis; Trichloroacetic Acid; Trityl Compounds | 1996 |
Developmental toxicity of trichloroethylene, tetrachloroethylene and four of their metabolites in rat whole embryo culture.
Topics: Animals; Chloral Hydrate; Chloroacetates; Culture Techniques; Dichloroacetic Acid; Embryo, Mammalian; Embryonic and Fetal Development; Liver; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethylene | 1995 |
Carcinogenic activity of dichloroacetic acid and trichloroacetic acid in the liver of female B6C3F1 mice.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Dichloroacetic Acid; Dose-Response Relationship, Drug; Female; Liver; Liver Neoplasms; Mice; Time Factors; Trichloroacetic Acid | 1996 |
Formation of dichloroacetic acid by rat and mouse gut microflora, an in vitro study.
Topics: Aerobiosis; Anaerobiosis; Analysis of Variance; Animals; Bacteria; Cecum; Dichloroacetic Acid; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred F344; Trichloroacetic Acid | 1996 |
Pharmacokinetic analysis of chloral hydrate and its metabolism in B6C3F1 mice.
Topics: Animals; Area Under Curve; Biotransformation; Chloral Hydrate; Dichloroacetic Acid; Glucuronates; Half-Life; Hypnotics and Sedatives; Injections, Intravenous; Liver; Male; Mice; Mice, Inbred Strains; Trichloroacetic Acid | 1996 |
Loss of heterozygosity on chromosome 6 in dichloroacetic acid and trichloroacetic acid-induced liver tumors in female B6C3F1 mice.
Topics: Animals; Chromosome Deletion; Dichloroacetic Acid; Female; Humans; Liver Neoplasms, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Trichloroacetic Acid | 1996 |
Promotion by mixtures of dichloroacetic acid and trichloroacetic acid of N-methyl-N-nitrosourea-initiated cancer in the liver of female B6C3F1 mice.
Topics: Animals; Body Weight; Carcinogens; Cocarcinogenesis; Dichloroacetic Acid; Drug Combinations; Female; Glutathione Transferase; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Methylnitrosourea; Mice; Organ Size; Time Factors; Trichloroacetic Acid; Water Pollutants, Chemical | 1997 |
Differences in phenotype and cell replicative behavior of hepatic tumors induced by dichloroacetate (DCA) and trichloroacetate (TCA).
Topics: Administration, Oral; Animals; Cell Count; Cell Division; Dichloroacetic Acid; Drinking; Immunohistochemistry; Liver; Liver Neoplasms; Male; Mice; Phenotype; Precancerous Conditions; Trichloroacetic Acid | 1997 |
Electrospray analysis of biological samples for trace amounts of trichloroacetic acid, dichloroacetic acid, and monochloroacetic acid.
Topics: Acetates; Administration, Inhalation; Dichloroacetic Acid; Humans; Mass Spectrometry; Reference Standards; Sensitivity and Specificity; Trichloroacetic Acid | 1997 |
Effect of pretreatment with dichloroacetate or trichloroacetate on the metabolism of bromodichloroacetate.
Topics: Acetates; Animals; Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Cytosol; Dichloroacetic Acid; Drug Interactions; Liver; Male; Mice; Microsomes, Liver; Trichloroacetic Acid; Water Supply | 1997 |
A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.
Topics: Administration, Oral; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Feces; Glucuronates; Liver; Male; Mice; Mice, Inbred Strains; Models, Biological; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1997 |
Comparative genotoxicity of halogenated acetic acids found in drinking water.
Topics: Acetates; Animals; Chloroacetates; Dichloroacetic Acid; DNA Damage; Escherichia coli; Hydrocarbons, Brominated; Micronucleus Tests; Mutagenicity Tests; Mutagens; Salamandridae; Salmonella typhimurium; SOS Response, Genetics; Trichloroacetic Acid; Water Supply | 1997 |
Mutagenicity of three disinfection by-products: di- and trichloroacetic acid and chloral hydrate in L5178Y/TK +/- (-)3.7.2C mouse lymphoma cells.
Topics: Animals; Chloral Hydrate; Chromosome Aberrations; Dichloroacetic Acid; Disinfectants; Leukemia L5178; Mice; Mutagenicity Tests; Mutagens; Thymidine Kinase; Trichloroacetic Acid; Tumor Cells, Cultured; Water Purification | 1998 |
Capillary zone electrophoresis with indirect UV detection of haloacetic acids in water.
Topics: Acetates; Cetrimonium; Cetrimonium Compounds; Chlorine; Dichloroacetic Acid; Disinfection; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Quaternary Ammonium Compounds; Surface-Active Agents; Trichloroacetic Acid; Trimethyl Ammonium Compounds; Water | 1998 |
Dichloroacetate and trichloroacetate promote clonal expansion of anchorage-independent hepatocytes in vivo and in vitro.
Topics: Administration, Oral; Animals; Cell Count; Cell Separation; Cells, Cultured; Dichloroacetic Acid; Dose-Response Relationship, Drug; Genes, fos; Genes, jun; Liver; Liver Neoplasms, Experimental; Male; Mice; Neoplastic Stem Cells; Phenotype; Trichloroacetic Acid | 1998 |
Effect of dichloroacetic acid and trichloroacetic acid on DNA methylation in liver and tumors of female B6C3F1 mice.
Topics: 5-Methylcytosine; Adenoma; Animals; Carcinogens; Cytosine; Dichloroacetic Acid; DNA Methylation; Female; Liver; Liver Neoplasms, Experimental; Mice; Trichloroacetic Acid | 1998 |
Kinetics of trichloroacetic acid and dichloroacetic acid in the isolated perfused rat liver.
Topics: Animals; Bile; Body Fluids; Dichloroacetic Acid; Environmental Pollutants; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Perfusion; Rats; Rats, Inbred F344; Trichloroacetic Acid | 1998 |
The extent of dichloroacetate formation from trichloroethylene, chloral hydrate, trichloroacetate, and trichloroethanol in B6C3F1 mice.
Topics: Animals; Biological Availability; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Half-Life; Male; Metabolic Clearance Rate; Mice; Models, Biological; Trichloroacetic Acid; Trichloroethylene | 1998 |
Biotransformation of perchloroethene: dose-dependent excretion of trichloroacetic acid, dichloroacetic acid, and N-acetyl-S-(trichlorovinyl)-L-cysteine in rats and humans after inhalation.
Topics: Acetylcysteine; Adult; Aged; Animals; Biotransformation; Carcinogens; Dichloroacetic Acid; Environmental Pollutants; Female; Half-Life; Humans; Inhalation Exposure; Male; Middle Aged; Rats; Rats, Wistar; Solvents; Tetrachloroethylene; Trichloroacetic Acid | 1998 |
Comparative study of a solid-phase extraction system coupled to capillary electrophoresis in the determination of haloacetic compounds in tap water.
Topics: Dichloroacetic Acid; Electrophoresis, Capillary; Reproducibility of Results; Trichloroacetic Acid; Water Pollutants, Chemical; Water Supply | 1998 |
Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice.
Topics: Adipose Tissue; Administration, Inhalation; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Kidney; Liver; Lung; Male; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Models, Biological; Oxidation-Reduction; Sensitivity and Specificity; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1999 |
Evaluation of biomarkers of environmental exposures: urinary haloacetic acids associated with ingestion of chlorinated drinking water.
Topics: Adolescent; Adult; Biomarkers; Chlorine; Dichloroacetic Acid; Environmental Exposure; Female; Half-Life; Humans; Middle Aged; Sensitivity and Specificity; Surveys and Questionnaires; Trichloroacetic Acid; Water Supply | 1999 |
Effect of enterohepatic circulation on the pharmacokinetics of chloral hydrate and its metabolites in F344 rats.
Topics: Animals; Area Under Curve; Bile; Chloral Hydrate; Dichloroacetic Acid; Disinfectants; Hypnotics and Sedatives; Intestine, Small; Liver; Male; Random Allocation; Rats; Rats, Inbred F344; Trichloroacetic Acid | 1999 |
Solid-phase microextraction coupled with gas chromatography-ion trap mass spectrometry for the analysis of haloacetic acids in water.
Topics: Acetates; Dichloroacetic Acid; Gas Chromatography-Mass Spectrometry; Trichloroacetic Acid; Water | 1999 |
Effect of pre-treatment with dichloroacetic or trichloroacetic acid in drinking water on the pharmacokinetics of a subsequent challenge dose in B6C3F1 mice.
Topics: Animals; Carbon Radioisotopes; Chromatography, Gas; Dichloroacetic Acid; Male; Mice; Rats; Trichloroacetic Acid; Water Supply | 1999 |
Determination of chloral hydrate metabolites in human plasma by gas chromatography-mass spectrometry.
Topics: Acetals; Acetates; Acidosis, Lactic; Administration, Oral; Child; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry; Glucuronates; Glucuronides; Humans; Hydroxamic Acids; Reproducibility of Results; Sensitivity and Specificity; Trichloroacetic Acid | 1999 |
Effect of trichloroethylene and its metabolites, dichloroacetic acid and trichloroacetic acid, on the methylation and expression of c-Jun and c-Myc protooncogenes in mouse liver: prevention by methionine.
Topics: Animals; Dichloroacetic Acid; DNA Methylation; DNA Primers; Female; Gene Expression; Liver; Methionine; Mice; Mice, Inbred Strains; Organ Size; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; RNA, Messenger; Trichloroacetic Acid; Trichloroethylene | 2000 |
Biologically based dose-response model for liver tumors induced by trichloroethylene.
Topics: Animals; Carcinogens, Environmental; Dichloroacetic Acid; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Models, Biological; Risk Assessment; Trichloroacetic Acid; Trichloroethylene | 2000 |
Hypomethylation and overexpression of c-jun and c-myc protooncogenes and increased DNA methyltransferase activity in dichloroacetic and trichloroacetic acid-promoted mouse liver tumors.
Topics: Alkylating Agents; Animals; Blotting, Northern; Blotting, Southern; Blotting, Western; Dichloroacetic Acid; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Liver Neoplasms, Experimental; Methylnitrosourea; Methyltransferases; Mice; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; RNA, Messenger; Trichloroacetic Acid | 2000 |
Trapping and identification of the dichloroacetate radical from the reductive dehalogenation of trichloroacetate by mouse and rat liver microsomes.
Topics: Animals; Dichloroacetic Acid; Free Radicals; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Models, Chemical; Oxidation-Reduction; Rats; Rats, Inbred F344; Trichloroacetic Acid | 2000 |
The fate and persistence of trifluoroacetic and chloroacetic acids in pond waters.
Topics: Acetates; Biodegradation, Environmental; Dichloroacetic Acid; Fresh Water; Trichloroacetic Acid; Trifluoroacetic Acid; Water Pollutants | 2001 |
The effect of the trichloroethylene metabolites trichloroacetate and dichloroacetate on peroxisome proliferation and DNA synthesis in cultured human hepatocytes.
Topics: Animals; Cell Division; Cells, Cultured; Dichloroacetic Acid; DNA; Hepatocytes; Humans; Liver; Mice; Palmitoyl Coenzyme A; Peroxisome Proliferators; Peroxisomes; Pyrimidines; Trichloroacetic Acid; Trichloroethylene | 2000 |
Determination of dichloroacetic acid and trichloroacetic acid by liquid-liquid extraction and ion chromatography.
Topics: Chlorine; Chromatography, Ion Exchange; Dichloroacetic Acid; Disinfectants; Trichloroacetic Acid | 2000 |
The effect of dichloroacetic acid and trichloroacetic acid on DNA methylation and cell proliferation in B6C3F1 mice.
Topics: Animals; Blotting, Southern; Carcinogens; Cell Division; Dichloroacetic Acid; DNA Methylation; DNA Replication; Female; Genes, myc; Kidney; Liver; Mice; Mice, Inbred Strains; Mitotic Index; Organ Size; Proliferating Cell Nuclear Antigen; Promoter Regions, Genetic; Time Factors; Trichloroacetic Acid; Urinary Bladder | 2001 |
Effect of chloroform on dichloroacetic acid and trichloroacetic acid-induced hypomethylation and expression of the c-myc gene and on their promotion of liver and kidney tumors in mice.
Topics: Animals; Carcinogens; Chloroform; Dichloroacetic Acid; DNA Methylation; Dose-Response Relationship, Drug; Drug Interactions; Female; Gene Expression; Genes, myc; Hepatocytes; Kidney Neoplasms; Liver Neoplasms; Mice; RNA, Messenger; Trichloroacetic Acid | 2001 |
Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene.
Topics: Animals; Blotting, Western; Dichloroacetic Acid; DNA, Neoplasm; Drug Interactions; Genes, jun; Genes, ras; Liver Neoplasms; Male; Mice; Mutation; Polymerase Chain Reaction; Random Allocation; Sequence Analysis, DNA; Solvents; Trichloroacetic Acid; Trichloroethylene | 2002 |
Vacancy ion-exclusion chromatography of haloacetic acids on a weakly acidic cation-exchange resin.
Topics: Acetates; Acetic Acid; Cation Exchange Resins; Chromatography, Ion Exchange; Dichloroacetic Acid; Electric Conductivity; Hydrogen-Ion Concentration; Reproducibility of Results; Sensitivity and Specificity; Solvents; Sulfuric Acids; Trichloroacetic Acid; Water | 2003 |
The induction of oxidative stress and cellular death by the drinking water disinfection by-products, dichloroacetate and trichloroacetate in J774.A1 cells.
Topics: Animals; Cell Death; Cell Line; Dichloroacetic Acid; Disinfection; Dose-Response Relationship, Drug; Oxidative Stress; Trichloroacetic Acid; Water Supply | 2003 |
Evaluation of the influence of chloroacetic acids on the pharmacokinetics of trihalomethanes in the rat.
Topics: Acetates; Animals; Area Under Curve; Dichloroacetic Acid; Disinfection; Drug Interactions; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Trichloroacetic Acid; Trihalomethanes; Water Purification | 2003 |
Hypomethylation of DNA and the insulin-like growth factor-II gene in dichloroacetic and trichloroacetic acid-promoted mouse liver tumors.
Topics: 5-Methylcytosine; Animals; Carcinogens; CpG Islands; Dichloroacetic Acid; DNA; DNA Methylation; Female; Immunohistochemistry; Insulin-Like Growth Factor II; Liver Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trichloroacetic Acid | 2004 |
Interactions in the tumor-promoting activity of carbon tetrachloride, trichloroacetate, and dichloroacetate in the liver of male B6C3F1 mice.
Topics: Administration, Oral; Animals; Carbon Tetrachloride; Carcinogens; Dichloroacetic Acid; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Trichloroacetic Acid; Urethane; Water Supply | 2004 |
Role of the peroxisome proliferator-activated receptor alpha (PPARalpha) in responses to trichloroethylene and metabolites, trichloroacetate and dichloroacetate in mouse liver.
Topics: Animals; Body Weight; Cell Division; Dichloroacetic Acid; Gene Expression Regulation; Hepatocytes; Liver; Mice; Organ Size; Oxidoreductases; PPAR alpha; Protein Array Analysis; Trichloroacetic Acid; Trichloroethylene | 2004 |
Some drinking-water disinfectants and contaminants, including arsenic.
Topics: Animals; Arsenic; Carcinogens, Environmental; Chloral Hydrate; Chloramines; Dichloroacetic Acid; Disinfectants; Furans; Humans; Trichloroacetic Acid; Water Pollutants, Chemical; Water Supply | 2004 |
Some drinking-water disinfectants and contaminants, including arsenic. Monographs on chloramine, chloral and chloral hydrate, dichloroacetic acid, trichloroacetic acid and 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone.
Topics: Animals; Carcinogens; Chloral Hydrate; Chloramines; Dichloroacetic Acid; Furans; Humans; Trichloroacetic Acid; Water Supply | 2004 |
Determination of dichloroacetic acid and trichloroacetic acid in drinking water by acidic methanol esterification and headspace gas chromatography.
Topics: Chromatography, Gas; Dichloroacetic Acid; Environmental Monitoring; Esterification; Methanol; Trichloroacetic Acid; Water Pollutants, Chemical; Water Supply | 2005 |
Lack of direct mitogenic activity of dichloroacetate and trichloroacetate in cultured rat hepatocytes.
Topics: Animals; Apoptosis; Carcinogens, Environmental; Cell Count; Cell Proliferation; Dexamethasone; Dichloroacetic Acid; Epidermal Growth Factor; Glucocorticoids; Hepatocytes; Liver Neoplasms, Experimental; Male; Mitogens; Rats; Rats, Long-Evans; Thymidine; Trichloroacetic Acid | 2005 |
DNA hypomethylation induced by drinking water disinfection by-products in mouse and rat kidney.
Topics: Acetates; Animals; Dichloroacetic Acid; Disinfectants; DNA Methylation; Female; Genes, myc; Kidney; Male; Methionine; Mice; Rats; Risk Assessment; Trichloroacetic Acid; Water Supply | 2005 |
[Adsorption performance of haloacetic acids onto 5 GACs from water].
Topics: Adsorption; Charcoal; Dichloroacetic Acid; Disinfectants; Temperature; Trichloroacetic Acid; Water Pollutants, Chemical; Water Purification; Water Supply | 2005 |
Comparison of haloacetic acids in the environment of the Northern and Southern Hemispheres.
Topics: Acetates; Canada; Chemical Precipitation; Chile; Dichloroacetic Acid; Environment; Industry; Malawi; Pinus; Plant Leaves; Soil; Soil Pollutants; Trichloroacetic Acid; United Kingdom | 2005 |
Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.
Topics: Animals; Bayes Theorem; Chloral Hydrate; Dichloroacetic Acid; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Humans; Kinetics; Markov Chains; Mice; Models, Biological; Monte Carlo Method; Rats; Sulfhydryl Compounds; Trichloroacetic Acid; Trichloroethylene | 2006 |
[Study on rat's DNA damage of p53 induced by chlorinated acetic acids of drinking water disinfection by-products].
Topics: Animals; Dichloroacetic Acid; DNA; DNA Damage; Exons; Genes, p53; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Trichloroacetic Acid | 2006 |
Kinetics of chloral hydrate and its metabolites in male human volunteers.
Topics: Adult; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Glucuronates; Humans; Liver; Male; Middle Aged; Time Factors; Trichloroacetic Acid | 2008 |
Dichloroacetate- and trichloroacetate-induced phagocytic activation and production of oxidative stress in the hepatic tissues of mice after acute exposure.
Topics: Animals; Cytochromes c; Dichloroacetic Acid; DNA Breaks, Single-Stranded; Lipid Peroxidation; Liver; Male; Mice; Oxidation-Reduction; Oxidative Stress; Peritoneal Lavage; Phagocytosis; Superoxides; Thiobarbituric Acid Reactive Substances; Trichloroacetic Acid | 2008 |
Fate of THMs and HAAs in low TOC surface water.
Topics: Acetates; Adsorption; Carbon; Chlorine; Dichloroacetic Acid; Disinfection; Filtration; Halogens; Korea; Seasons; Trichloroacetic Acid; Trihalomethanes; Water Pollutants, Chemical; Water Purification | 2009 |
Determination of ten haloacetic acids in drinking water using high-performance and ultra-performance liquid chromatography-tandem mass spectrometry.
Topics: Acetates; Chromatography, High Pressure Liquid; Dichloroacetic Acid; Halogens; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Trichloroacetic Acid; Water | 2009 |
Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine.
Topics: Administration, Oral; Animals; Biological Availability; Carcinogens; Cysteine; Dichloroacetic Acid; Glutathione; Half-Life; Male; Mice; Models, Biological; Oxidation-Reduction; Risk Assessment; Time Factors; Trichloroacetic Acid; Trichloroethylene | 2009 |
Liquid chromatography electrospray ionization tandem mass spectrometry analysis method for simultaneous detection of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine.
Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Dichloroacetic Acid; Glutathione; Male; Mice; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Trichloroacetic Acid; Trichloroethylene | 2009 |
Dichloroacetate- and trichloroacetate-induced oxidative stress in the hepatic tissues of mice after long-term exposure.
Topics: Administration, Oral; Animals; Carcinogens; Dichloroacetic Acid; DNA; DNA Breaks, Single-Stranded; Hepatomegaly; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred Strains; Organ Size; Oxidative Stress; Superoxides; Trichloroacetic Acid | 2010 |
Potential of the TCE-degrading endophyte Pseudomonas putida W619-TCE to improve plant growth and reduce TCE phytotoxicity and evapotranspiration in poplar cuttings.
Topics: Biodegradation, Environmental; Dichloroacetic Acid; Plant Transpiration; Populus; Pseudomonas putida; Soil Pollutants; Symbiosis; Trichloroacetic Acid; Trichloroethanes; Xylem | 2010 |
Effects of chlorinated acetates on the glutathione metabolism and on glycolysis of cultured astrocytes.
Topics: Acetates; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Dichloroacetic Acid; Glutathione; Glycolysis; Rats; Rats, Wistar; Trichloroacetic Acid | 2011 |
Further optimization of detritylation in solid-phase oligodeoxyribonucleotide synthesis.
Topics: Acids; Dichloroacetic Acid; Hydrogen-Ion Concentration; Indicators and Reagents; Oligodeoxyribonucleotides; Trichloroacetic Acid; Trityl Compounds | 2011 |
Haloacetic acids in swimming pools: swimmer and worker exposure.
Topics: Acetates; Adult; Child; Dichloroacetic Acid; Female; Humans; Male; Occupational Exposure; Swimming; Swimming Pools; Trichloroacetic Acid; Water | 2011 |
Formation of disinfection byproducts in typical Chinese drinking water.
Topics: China; Chlorine; Chloroform; Dichloroacetic Acid; Disinfectants; Disinfection; Drinking Water; Humans; Seasons; Trichloroacetic Acid; Trihalomethanes; Water Pollutants; Water Purification | 2011 |
Vitamin E restriction in the diet enhances phagocytic activation by dichloroacetate and trichloroacetate in mice.
Topics: Animals; Dichloroacetic Acid; Diet; Enzymes; Macrophage Activation; Male; Mice; Phagocytes; Trichloroacetic Acid; Vitamin E | 2012 |
Haloacetic acid removal by sequential zero-valent iron reduction and biologically active carbon degradation.
Topics: Adsorption; Charcoal; Chloroacetates; Dichloroacetic Acid; Iron; Kinetics; Trichloroacetic Acid; Water Pollutants, Chemical; Water Purification | 2013 |
The occurrence of disinfection by-products in municipal drinking water in China's Pearl River Delta and a multipathway cancer risk assessment.
Topics: China; Chloroform; Cities; Dichloroacetic Acid; Disinfectants; Disinfection; Drinking Water; Humans; Neoplasms; Public Health; Risk Assessment; Rivers; Seasons; Trichloroacetic Acid; Trihalomethanes; Water Pollutants, Chemical | 2013 |
The induction of phagocytic activation by mixtures of the water chlorination by-products, dichloroacetate- and trichloroacetate, in mice after subchronic exposure.
Topics: Animals; Dichloroacetic Acid; Environmental Exposure; Halogenation; Male; Mice; Peritoneal Lavage; Peroxidase; Phagocytosis; Superoxides; Trichloroacetic Acid; Tumor Necrosis Factor-alpha; Water | 2013 |
Metabolomics reveals trichloroacetate as a major contributor to trichloroethylene-induced metabolic alterations in mouse urine and serum.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Dichloroacetic Acid; Fatty Acids; Hepatomegaly; Homeostasis; Male; Metabolism; Metabolomics; Mice; Mice, Inbred C57BL; Multivariate Analysis; Phospholipids; Polymerase Chain Reaction; Spectrometry, Mass, Electrospray Ionization; Trichloroacetic Acid; Trichloroethylene | 2013 |
Predictive model for disinfection by-product in Alexandria drinking water, northern west of Egypt.
Topics: Chlorine; Dichloroacetic Acid; Disinfectants; Disinfection; Drinking Water; Egypt; Environmental Monitoring; Humans; Models, Chemical; Trichloroacetic Acid; Trihalomethanes; Water Pollutants, Chemical; Water Purification | 2013 |
A convenient and sensitive method for haloacetic acid analysis in tap water by on-line field-amplified sample-stacking CE-ESI-MS.
Topics: Acetates; Dichloroacetic Acid; Electrophoresis, Capillary; Spectrometry, Mass, Electrospray Ionization; Trichloroacetic Acid; Water Supply | 2013 |
DBP formation in hot and cold water across a simulated distribution system: effect of incubation time, heating time, pH, chlorine dose, and incubation temperature.
Topics: Acetates; Acetonitriles; Chlorine; Dichloroacetic Acid; Disinfection; Drinking Water; Halogenation; Hydrogen-Ion Concentration; Propane; Temperature; Time Factors; Trichloroacetic Acid; Water; Water Supply | 2013 |
Clustering chlorine reactivity of haloacetic acid precursors in inland lakes.
Topics: Chlorine; Cluster Analysis; Dichloroacetic Acid; Disinfection; Environment; Halogenation; Kinetics; Lakes; Midwestern United States; Models, Chemical; Trichloroacetic Acid; Water Pollutants, Chemical; Water Supply | 2014 |
The effects of mixtures of dichloroacetate and trichloroacetate on induction of oxidative stress in livers of mice after subchronic exposure.
Topics: Animals; Biomarkers; Dichloroacetic Acid; DNA Breaks, Single-Stranded; Dose-Response Relationship, Drug; Halogenation; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred Strains; Oxidative Stress; Regression Analysis; Superoxides; Trichloroacetic Acid; Water Pollutants, Chemical | 2014 |
Influencing factors of disinfection byproducts formation during chloramination of Cyclops metabolite solutions.
Topics: Animals; Chloramines; Chloroform; Copepoda; Culture Media; Dichloroacetic Acid; Disinfection; Trichloroacetic Acid | 2014 |
Cancer risk assessment on trihalomethanes and haloacetic acids in drinking water of China using disability-adjusted life years.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; China; Dichloroacetic Acid; Humans; Infant; Middle Aged; Neoplasms; Risk Assessment; Trichloroacetic Acid; Trihalomethanes; Uncertainty; Water Pollutants, Chemical; Young Adult | 2014 |
Temporal variability in urinary levels of drinking water disinfection byproducts dichloroacetic acid and trichloroacetic acid among men.
Topics: Adult; Biomarkers; China; Chromatography, Gas; Dichloroacetic Acid; Disinfectants; Drinking Water; Environmental Exposure; Environmental Monitoring; Humans; Male; Sensitivity and Specificity; Time Factors; Trichloroacetic Acid | 2014 |
Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects.
Topics: Administration, Oral; Animals; Carcinogens; Cell Proliferation; Cysteine; Cytochrome P-450 Enzyme System; Dichloroacetic Acid; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Gene Expression; Glutathione; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction; Oxidative Stress; Real-Time Polymerase Chain Reaction; Solvents; Trichloroacetic Acid; Trichloroethylene | 2015 |
Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.
Topics: Animals; Carcinogens; Cell Proliferation; Cysteine; Cytochrome P-450 Enzyme System; Dichloroacetic Acid; Ethylene Chlorohydrin; Glutathione; Hepatitis A Virus Cellular Receptor 1; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction; PPAR alpha; Trichloroacetic Acid; Trichloroethylene | 2015 |
Haloacetic acids content of fruit juices and soft drinks.
Topics: Beverages; Carbonated Beverages; Dichloroacetic Acid; Disinfection; Fruit; Gas Chromatography-Mass Spectrometry; Trichloroacetic Acid; Water Purification | 2015 |
Effect of dissolved oxygen concentration on iron efficiency: Removal of three chloroacetic acids.
Topics: Acetates; Dichloroacetic Acid; Iron; Oxygen; Trichloroacetic Acid; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2015 |
Dichloroacetate and Trichloroacetate Toxicity in AML12 Cells: Role of Oxidative Stress.
Topics: Animals; Cell Line; Dichloroacetic Acid; Hepatocytes; Lipid Peroxidation; Mice; Superoxide Dismutase; Trichloroacetic Acid | 2015 |
Simultaneous determination of three chloroacetic acids, three herbicides, and 12 anions in water by ion chromatography.
Topics: Acetates; Anions; Benzothiadiazines; Chlorine; Chloroacetates; Chromatography, Ion Exchange; Dichloroacetic Acid; Glycine; Glyphosate; Herbicides; Ions; Limit of Detection; Picloram; Reproducibility of Results; Trichloroacetic Acid; Water | 2015 |
TRICHLOROETHYLENE, TETRACHLOROETHYLENE, AND SOME OTHER CHLORINATED AGENTS.
Topics: Animals; Carcinogenicity Tests; Carcinogens, Environmental; Chloral Hydrate; Dichloroacetic Acid; Ethane; Humans; Hydrocarbons, Chlorinated; Neoplasms; Risk Assessment; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethylene | 2014 |
Trichloroethylene and Its Oxidative Metabolites Enhance the Activated State and Th1 Cytokine Gene Expression in Jurkat Cells.
Topics: Cell Differentiation; Cytokines; Dichloroacetic Acid; Environmental Pollutants; Gene Expression Regulation; Humans; Jurkat Cells; RNA, Messenger; Th1 Cells; Trichloroacetic Acid; Trichloroethylene | 2015 |
Biologically active carbon filtration for haloacetic acid removal from swimming pool water.
Topics: Charcoal; Chloroacetates; Dichloroacetic Acid; Disinfection; Filtration; Swimming Pools; Trichloroacetic Acid; Water Pollutants, Chemical; Water Purification | 2016 |
Probing Coagulation Behavior of Individual Aluminum Species for Removing Corresponding Disinfection Byproduct Precursors: The Role of Specific Ultraviolet Absorbance.
Topics: Aluminum Chloride; Aluminum Compounds; Aluminum Hydroxide; Chlorides; Chloroform; Dichloroacetic Acid; Disinfectants; Flocculation; Freeze Drying; Humans; Humic Substances; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Principal Component Analysis; Trichloroacetic Acid; Trihalomethanes; Ultraviolet Rays; Water Pollutants, Chemical; Water Purification | 2016 |
In vitro bioacessibility and transport across Caco-2 monolayers of haloacetic acids in drinking water.
Topics: Acetates; Caco-2 Cells; Cell Membrane Permeability; Dichloroacetic Acid; Disinfection; Drinking Water; Humans; Tandem Mass Spectrometry; Trichloroacetic Acid; Water Pollutants, Chemical; Water Purification; Water Supply | 2016 |
Associations Between Disinfection By-Product Exposures and Craniofacial Birth Defects.
Topics: Abnormalities, Multiple; Acetates; Adult; Case-Control Studies; Chloroform; Cleft Lip; Cleft Palate; Craniofacial Abnormalities; Dichloroacetic Acid; Dietary Exposure; Disinfectants; Drinking Water; Ear; Eye Abnormalities; Female; Humans; Infant, Newborn; Male; Pregnancy; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects; Trichloroacetic Acid; Trihalomethanes; Water Purification; Young Adult | 2018 |
Chlorination by-product levels in hot tap water: Significance and variability.
Topics: Dichloroacetic Acid; Disinfectants; Drinking Water; Environmental Monitoring; Halogenation; Heating; Quebec; Trichloroacetic Acid; Trihalomethanes; Water Pollutants, Chemical | 2019 |
Profiles, variability and predictors of concentrations of blood trihalomethanes and urinary haloacetic acids along pregnancy among 1760 Chinese women.
Topics: Biomarkers; China; Dichloroacetic Acid; Environmental Exposure; Female; Humans; Pregnancy; Trichloroacetic Acid; Trihalomethanes; Water Pollutants, Chemical | 2019 |
Degradation of haloacetic acids with the Fenton-like and analysis by GC-MS: use of bioassays for monitoring of genotoxic, mutagenic and cytotoxic effects.
Topics: Acetates; Acetic Acid; Biological Assay; Chloroacetates; Dichloroacetic Acid; DNA Damage; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Hydrocarbons, Brominated; Mutagens; Toxicity Tests; Trichloroacetic Acid; Water; Water Supply | 2019 |
The critical role for TAK1 in trichloroethylene-induced contact hypersensitivity in vivo and in CD4
Topics: Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cytokines; Dermatitis, Contact; Dichloroacetic Acid; Female; JNK Mitogen-Activated Protein Kinases; Local Lymph Node Assay; MAP Kinase Kinase Kinases; Mice, Inbred C57BL; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Trichloroacetic Acid; Trichloroethylene | 2019 |
Formation and interdependence of disinfection byproducts during chlorination of natural organic matter in a conventional drinking water treatment plant.
Topics: Acetonitriles; Chloroform; Dichloroacetic Acid; Disinfectants; Disinfection; Drinking Water; Halogenation; Humic Substances; Trichloroacetic Acid; Ultrafiltration; Water Pollutants, Chemical; Water Purification | 2020 |
Associations of urinary dichloroacetic acid and trichloroacetic acid exposure with platelet indices: Exploring the mediating role of blood pressure in the general population.
Topics: Adult; Blood Pressure; China; Cross-Sectional Studies; Dichloroacetic Acid; Humans; Trichloroacetic Acid | 2021 |
Exposure to disinfection by-products and reproductive hormones among women: Results from the Tongji Reproductive and Environmental (TREE) study.
Topics: Biomarkers; Dichloroacetic Acid; Disinfection; Female; Hormones; Humans; Trichloroacetic Acid | 2022 |
Chlorine decay and disinfection by-products transformation under booster chlorination conditions: A pilot-scale study.
Topics: Chlorides; Chlorine; Dichloroacetic Acid; Disinfectants; Disinfection; Halogenation; Iron; Steel; Trichloroacetic Acid; Trihalomethanes; Water; Water Pollutants, Chemical; Water Purification | 2022 |
Associations between urinary biomarkers of exposure to disinfection byproducts and semen parameters: A repeated measures analysis.
Topics: Adult; Biomarkers; Dichloroacetic Acid; Disinfection; Humans; Male; Semen; Semen Analysis; Sperm Motility; Trichloroacetic Acid | 2024 |
Sub-lethal toxicity of five disinfection by-products on microalgae determined by flow cytometry - Lines of evidence for adverse outcome pathways.
Topics: Adverse Outcome Pathways; Dichloroacetic Acid; Disinfection; Flow Cytometry; Microalgae; Reactive Oxygen Species; Trichloroacetic Acid | 2023 |
Measurement of haloacetic acids in human urine samples from six megacities of China using a refined detection method.
Topics: Adult; China; Cities; Dichloroacetic Acid; Disinfection; Humans; Trichloroacetic Acid; Water; Water Supply | 2024 |