Page last updated: 2024-08-17

dichloroacetic acid and oxalates

dichloroacetic acid has been researched along with oxalates in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199010 (58.82)18.7374
1990's6 (35.29)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crabb, DW; Harris, RA1
Cepanec, C; Demaugre, F; Leroux, JP1
Chu, PI; Curry, SH; Limacher, M; Lorenz, A; Stacpoole, PW1
Cameron, DF; Cornwell, PE; Curry, SH; Harwood, HJ; Samuelson, DA; Sauberlich, HE; Stacpoole, PW1
London, RE; Perlman, ME; Selinsky, BS1
Baumgartner, TG; Chu, PI; Curry, SH; Stacpoole, PW1
Harwood, HJ; Stacpoole, PW; Varnado, CE1
Harris, RA; Yount, EA1
Buc, HA; Cepanec, C; Demaugre, F; Leroux, JP; Moncion, A1
Buc, HA; Demaugre, F; Leroux, JP; Moncion, A1
Evans, OB; Stacpoole, PW1
Bantle, JA; Fort, DJ; Hull, M; Rayburn, JR; Stover, EL1
Schwille, PO; Sharma, V1
Bull, RJ; Gonzalez-Leon, A; Schultz, IR; Xu, G1
Elfarra, AA; Krause, RJ; Lash, LH; Last, AR; Parker, JC1
Mode, DF; Nogueira, RF; Trovó, AG1

Trials

1 trial(s) available for dichloroacetic acid and oxalates

ArticleYear
Disposition and pharmacodynamics of dichloroacetate (DCA) and oxalate following oral DCA doses.
    Biopharmaceutics & drug disposition, 1991, Volume: 12, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Biotransformation; Blood Pressure Monitors; Dichloroacetic Acid; Echocardiography; Female; Half-Life; Heart Rate; Humans; Male; Middle Aged; Oxalates; Sex Factors

1991

Other Studies

16 other study(ies) available for dichloroacetic acid and oxalates

ArticleYear
Mechanism responsible for the hypoglycemic actions of dichloroacetate and 2-chloropropionate.
    Archives of biochemistry and biophysics, 1979, Volume: 198, Issue:1

    Topics: Acetates; Animals; Blood Glucose; Dichloroacetic Acid; Dihydroxyacetone; Fasting; Gluconeogenesis; Glyoxylates; Hydrocarbons, Chlorinated; In Vitro Techniques; Ketone Bodies; Lactates; Liver; Male; Oxalates; Propionates; Pyruvates; Rats

1979
Metabolic effects of dichloroacetate.
    The New England journal of medicine, 1978, Aug-03, Volume: 299, Issue:5

    Topics: Acetates; Animals; Dichloroacetic Acid; Fatty Acids; Gluconeogenesis; Leucine; Oxalates; Rats

1978
Characterization of oxalate as a catabolite of dichloroacetate responsible for the inhibition of gluconeogenesis and pyruvate carboxylation in rat liver cells.
    Biochemical and biophysical research communications, 1978, Dec-14, Volume: 85, Issue:3

    Topics: Acetates; Animals; Dichloroacetic Acid; Fasting; Gluconeogenesis; In Vitro Techniques; Kinetics; Liver; Mitochondria, Liver; Oxalates; Pyruvate Carboxylase; Pyruvates; Rats

1978
Chronic toxicity of dichloroacetate: possible relation to thiamine deficiency in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1990, Volume: 14, Issue:2

    Topics: Acetates; Animals; Body Weight; Dichloroacetic Acid; Erythrocytes; Male; Oxalates; Rats; Rats, Inbred Strains; Thiamine Deficiency; Time Factors; Transketolase

1990
In vivo nuclear magnetic resonance studies of hepatic methoxyflurane metabolism. II. A reevaluation of hepatic metabolic pathways.
    Molecular pharmacology, 1988, Volume: 33, Issue:5

    Topics: Animals; Dichloroacetic Acid; Fluorides; Liver; Magnetic Resonance Spectroscopy; Methoxyflurane; Oxalates; Rats

1988
Plasma concentrations and metabolic effects of intravenous sodium dichloroacetate.
    Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:1

    Topics: Acetates; Adult; Animals; Dichloroacetic Acid; Dose-Response Relationship, Drug; Female; Humans; Infusions, Parenteral; Kinetics; Lactates; Lactic Acid; Male; Middle Aged; Oxalates; Oxalic Acid; Rats

1985
Regulation of rat liver hydroxymethylglutaryl coenzyme A reductase by a new class of noncompetitive inhibitors. Effects of dichloroacetate and related carboxylic acids on enzyme activity.
    The Journal of clinical investigation, 1983, Volume: 72, Issue:5

    Topics: Acetates; Animals; Cholesterol; Dichloroacetic Acid; Dose-Response Relationship, Drug; Glyoxylates; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Male; Microsomes, Liver; Oxalates; Oxalic Acid; Rats; Rats, Inbred Strains

1983
Studies on the inhibition of gluconeogenesis by oxalate.
    Biochimica et biophysica acta, 1980, Nov-17, Volume: 633, Issue:1

    Topics: Angiotensins; Animals; Blood Glucose; Calcium; Cells, Cultured; Dichloroacetic Acid; Edetic Acid; Egtazic Acid; Epinephrine; Female; Gluconeogenesis; Liver; Liver Glycogen; Oxalates; Rats; Vasopressins

1980
Comparison of the effects of 2-chloropropionate and dichloroacetate on ketogenesis and lipogenesis in isolated rat hepatocytes.
    Biochemical pharmacology, 1983, Jun-15, Volume: 32, Issue:12

    Topics: Acetates; Animals; Dichloroacetic Acid; Drug Interactions; Hydrocarbons, Chlorinated; In Vitro Techniques; Ketone Bodies; Ketones; Lipids; Liver; Male; Oxalates; Propionates; Pyruvates; Rats; Rats, Inbred Strains

1983
Effects of oxalate and dichloroacetate on lipogenesis and ketogenesis in rat hepatocytes.
    Biochemical and biophysical research communications, 1982, Feb-11, Volume: 104, Issue:3

    Topics: Acetates; Acetyl Coenzyme A; Animals; Dichloroacetic Acid; Female; Ketone Bodies; Lipid Metabolism; Liver; Oxalates; Oxalic Acid; Pyruvate Decarboxylase; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains

1982
Prolonged hypolactatemia and increased total pyruvate dehydrogenase activity by dichloroacetate.
    Biochemical pharmacology, 1982, Apr-01, Volume: 31, Issue:7

    Topics: Acetates; Animals; Blood Glucose; Dichloroacetic Acid; Glyoxylates; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oxalates; Oxalic Acid; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors

1982
Evaluation of the developmental toxicity of trichloroethylene and detoxification metabolites using Xenopus.
    Teratogenesis, carcinogenesis, and mutagenesis, 1993, Volume: 13, Issue:1

    Topics: Animals; Carbon Monoxide; Cyclohexanes; Cyclohexenes; Dichloroacetic Acid; Epoxide Hydrolases; Ethylene Chlorohydrin; In Vitro Techniques; Inactivation, Metabolic; Male; Mixed Function Oxygenases; Oxalates; Oxalic Acid; Rats; Rats, Sprague-Dawley; Teratogens; Trichloroacetic Acid; Trichloroethylene; Xenopus laevis

1993
Sulfite inhibits oxalate production from glycolate and glyoxylate in vitro and from dichloroacetate infused i.v. into male rats.
    Biochemical medicine and metabolic biology, 1993, Volume: 49, Issue:2

    Topics: Alcohol Oxidoreductases; Animals; Dichloroacetic Acid; Glycolates; Glyoxylates; L-Lactate Dehydrogenase; Liver; Male; Muscles; Oxalates; Oxalic Acid; Rabbits; Rats; Rats, Sprague-Dawley; Sulfites

1993
Pharmacokinetics and metabolism of dichloroacetate in the F344 rat after prior administration in drinking water.
    Toxicology and applied pharmacology, 1997, Volume: 146, Issue:2

    Topics: Administration, Oral; Animals; Carbon Dioxide; Carbon Radioisotopes; Chromatography, Gas; Cytosol; Dichloroacetic Acid; Dose-Response Relationship, Drug; Drinking; Fresh Water; Glycolates; Glyoxylates; In Vitro Techniques; Injections, Intravenous; Liver; Male; Oxalates; Rats; Rats, Inbred F344

1997
Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:8

    Topics: Acetates; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Female; Glyoxylates; Humans; Kinetics; Male; Mice; Microsomes, Liver; NADP; Oxalates; Oxalic Acid; Rats; Rats, Inbred F344; Sex Factors; Solvents; Species Specificity; Trichloroethylene

1998
Solar photodegradation of dichloroacetic acid and 2,4-dichlorophenol using an enhanced photo-Fenton process.
    Chemosphere, 2002, Volume: 48, Issue:4

    Topics: Anthelmintics; Chlorophenols; Dichloroacetic Acid; Oxalates; Photochemistry; Seasons; Sunlight

2002